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Polysorbate 80 is often used as a stabilizer, emulsifier, and thickener.
Polysorbate 80 used in cosmetics is considered safe and has been approved by regulatory agencies such as the US Food and Drug Administration (FDA) and the European Union (EU).
Polysorbate 80 is used in the pharmaceutical industry as a solubilizing agent in medications and injectable drugs.
CAS Number: 9005-65-6
EC Number： 500-019-9
Chemical formula: C64H124O26
Molecular Weight (g/mol): 604.82
SYNONYMS:
Polyoxyethylene (20) sorbitan monooleate, Kolliphor PS 80, Montanox 80, Alkest TW 80, Tween 80, PS 80, Kotilen-80, Polyoxyethylene 20 sorbitane molooleate, Peg 3 Sorbitane Oleate, Inhibited Ethylene Glycol, Inhibited ethylene glycol, antifreeze, Polysorbate 80, E 433, Polyethoxylated Sorbitan Monooleate, Polyoxyethylene sorbitan monooleate (polysorbate 80), polyoxyethylene sorbitan monoleate, Sorbitan,mono-(9Z)-9-octadecenoate,poly(oxy-1,2-ethanediyl) derivs., Sorbitan,monooleate,polyoxyethylene derivs., Sorbitan,mono-9-octadecenoate,poly(oxy-1,2-ethanediyl) derivs.,(Z)-, Glycols,polyethylene,ether with sorbitan monooleate, Olothorb, Polyoxyethylene sorbitan monooleate, Polysorban 80, Sorlate, Tween 80A, Tween 81, Crillet 4, Hodag SVO 9, Polyethylene glycol sorbitan monooleate, Hexaethylene glycol sorbitan monooleate, Tris(polyoxyethylene)sorbitan monooleate, Polyoxyethylenesorbitan oleate, Ethoxylated sorbitan monooleate, Sorbimacrogol oleate, Polyoxyethylene monosorbitan monooleate, Polyoxyethylated sorbitan monooleate, Ethylene oxide-sorbitan monooleate polymer, Sorbital O 20, Crill 10, Crill 11, Crill S 10, Polysorbate 81, Emsorb 6900, Glycosperse O 20, Sorbon T 80, Durfax 80, SVO 9, Nikkol TO 10, Atlox 1087, Sorbitan monooleate polyethylene glycol ether, Romulgin O, Polyethylene glycol sorbitan ether monooleate, Atlox 8916TF, MO 55F, Polyethoxylated sorbitan monooleate, Setrolene O, Emulson 10OM, Nikkol TO 10M, Tween 18:1c, Nikkol TO 106, Sorbitan monooleate polyoxyethylene ether, Crillet 41, Rheodol TW-O 120, Ionet T 80, Value TN 80, Sorgen TW 80, Rheodol TW-O 106, Ionet T 80C, Sorbitan oleate-ethylene oxide adduct, Flo Mo SMO 20, Eumulgin SMO 20, Disponil SMO 120, PEG-20 Sorbitan Monooleate, Polysorbate 80, E433, PS80, Polyethylene sorbitan monooleate, Ethoxylated sorbitan monooleate, Polyoxyethylene sorbitan monooctadecenoate, Polysorban, Polyethylene glycol, sorbitan monooleate, CAS 9005-65-6, Tween 80, Polyoxyethylene [80] Sorbitan Monooleate, Glycosperse O 5, Alkamuls PSMO 20, Cemesol TW 1020, Nissan Nonion OT 221, TO 10M, Sorbitan monooleate ethylene oxide adduct, Witconol 2722, Rheodol Super TW-O 120, Cemerol T 80, Nonion OT 221, Crillet 4 Super, Silvan T 80, Radiasurf 7157, Myvatex MSPS, Polisorbac 60, T-MAZ 80, T-MAZ 80K, T 80C, Sorbimacrogol oleate 100, Sorbimacrogol oleate 300, Emasol O 105R, Rheodol TQ-O 106, Capmul POE-O, Sorbax PMO 20, Alkamuls T 80, T-MAZ 81, Ecoteric T 80, Montanox 81VG, TW-O 120, Montanox DF 80, Lamesorb SMO 20, POE sorbitan monooleate, Soporol 120, Nonio-light 0-30, Nonio-light SPO 1, Rheodol TW-O 120V, E 433, E 433 (polyglycol), PEO(20) sorbitan monooleate, Rheodol TW-O 106V, Ethylan GE 08, Canarcel TW 80, Ionet-T 80PA, Nikkol TO 10V, PEG sorbitan monooleat, PEG-20 Sorbitan Monooleate, Polysorbate 80, E433, PS80, Polyethylene sorbitan monooleate, Ethoxylated sorbitan monooleate, Polyoxyethylene sorbitan monooctadecenoate, Polysorban, Polyethylene glycol, sorbitan monooleate, Polyoxyethylene (80) sorbitan monooleate, Kolliphor PS 80, Montanox 80, Alkest TW 80, Tween 80, PS 80, Kotilen-80, Polysorbate 80, 6OZP39ZG8H, Monitan, Sorbimacrogol oleate 300, Armotan PMO-20, Atlox 1087, Capmul POE-O, Crillet 4, Drewmulse poe-smo, Durfax 80, Emsorb 6900, Ethoxylated sorbitan monooleate, MO 55F, Montanox 80, NCI-C60286, Polyethylene glycol 300 sorbitan monooleate, Polyethylene oxide sorbitan mono-oleate, Polyoxyethylene (5) sorbitan monooleate, Polyoxyethylene 20 sorbitan monooleate, Polyoxyethylene sorbitan oleate, Polysorban 80, Protasorb O-20, Romulgin O, SVO 9, Sorbon T 80, Sorlate, Atlox 8916TF, Avitears, CHEBI:53426, Cemerol T 80, Cemesol TW 1020, Crill 10, Crill 11, Crill S 10, Crillet 4 Super, Crillet 41, Disponil SMO 120, Eumulgin SMO 20, FEMA No. 2917, Flo Mo SMO 20, Glycol (Polysorbate 80), Glycols, polyethylene, ether with sorbitan monooleate, Glycosperse O 20, Glycosperse O 5, Glycosperse O-20, Glycosperse O-20 VEG, Glycosperse O-20X, Hodag SVO 9, IV Solution Stabilizer, Myvatex MSPS, Nikkol TO, Nikkol TO 10, Nikkol TO 10M, Nissan Nonion OT 221, Nonion OT 221, Olothorb, PEG-3 Sorbitan oleate, Peg-20 sorbitan oleate, Polisorbac 60, Polyethylene glycol (3) sorbitan monooleate, Polyoxyethylene (20) sorbitan monooleate, Polyoxyethylene (3) sorbitan monooleate, Polysorbate 80 B.P.C., Polysorbate 80 BPC, Polysorbate 80, USP, Sorbimacrogol oleate, Sorbitan, monooleate polyoxyethylene deriv., Sorbitan, monooleate, polyoxyethylene derives, T-Maz 80, TO 10, Tween 80, Polyoxyethylene [80] Sorbitan Monooleate, (X)-SORBITAN MONO-9-OCTADECENOATE POLY(OXY-1,2-ETHANEDIYL) DERIVS, (Z)-sorbitan mono-9-octadecenoate poly(oxy 1,2-ethanediyl) derivatives, 80s, Polysorbate, ALKAMULS PSMO 20, Akamuls PSMO 20, Alkamuls T 80, Atlas E, Atolox 8916TF, CCRIS 700, Cremophor PS 80, Crillet 50, DTXSID0021175, Drewpone 80K, E-433, EC 500-019-9, EMULSON 10OM, ETHYLENE OXIDE-SORBITAN MONOOLEATE POLYMER, Ecoteric T 80, Emasol O 105R, Emrite 6120, Emulson 100M, Eumulgin SMO, GLYCOSPERSE 0-20, GLYCOSPERSE 0-20 VEG, GLYCOSPERSE 0-20X, HEXAETHYLENE GLYCOL SORBITAN MONOOLEATE, HSDB 4359, Hodag PSMO-20, INS NO.433, INS-433, IONET T 80, IONET T 80C, IV STABILIZER, LIPOSORB 0-20, Liposorb O-20, MF59 COMPONENT TWEEN 80, NIKKOL TO 106, POLYETHOXYLATED SORBITAN MONOOLEATE, POLYETHYLENE GLYCOL SORBITAN ETHER MONOOLEATE, POLYETHYLENE GLYCOL SORBITAN MONOOLEATE, POLYOXYETHYLATED SORBITAN MONOOLEATE, POLYOXYETHYLENE MONOSORBITAN MONOOLEATE, POLYOXYETHYLENE(20)SORBITAN MONO-OLEATE, POLYOXYETHYLENE(20)SORBITAN MONOOLEATE, POLYOXYETHYLENESORBITAN OLEATE, POLYSORBATA 80, POLYSORBATE 80 (EP MONOGRAPH), POLYSORBATE 80 (II), POLYSORBATE 80 (MART.), POLYSORBATE 80 (USP-RS), POLYSORBATE 80,U.S.P., Peg sorbitan oleate, Poly(20)oxyethylene sorbitan monooleate, Polyethylene sorbitan monooleate, Polyoxyethylene 20 oleate, Polyoxyethylene(20) sorbitan monooleate, Polysorbate 80, U.S.P., Polysorbate 80s, Polysorbatum 80, RADIASURF 7157, RHEODOL SUPER TW-O 120, RHEODOL TW-O 106, RHEODOL TW-O 120, Ritabate 80, SETROLENE O, SILVAN T 80, SORBAX PMO-20, SORBIMACROGOL OLEATE 100, SORBITAL O 20, SORBITAN MONO-OLEATE POLYOXYETHYLENE, SORBITAN MONOLEATE, SORBITAN MONOOLEATE ETHYLENE OXIDE ADDUCT, SORBITAN MONOOLEATE POLYETHYLENE GLYCOL ETHER, SORBITAN MONOOLEATE POLYOXYETHYLENE ETHER, SORBITAN OLEATE-ETHYLENE OXIDE ADDUCT, SORBITAN, MONO-9-OCTADECENOATE, POLY(OXY-1,2-ETHANEDIYL) DERIVS., (Z)-, SORBITAN, MONOOLEATE, POLYOXYETHYLENE DERIVS., SORETHYTAN (20) MONO-OLEATE, SORGEN TW 80, Sorbital 0 20, Sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl) derivatives, Sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., Sorethytan (20) monooleate, Sorethytan oleate, T 80C, T-MAZ 80K, TO 10M, TRIS(POLYOXYETHYLENE)SORBITAN MONOOLEATE, TWEEN 18:1C, TWEEN 80A, TWEEN-80, Tego SMO 80, Tego SMO 80V, Tween 80 A, UNII-2MSF640LWM, UNII-58O7V09UCI, UNII-6OZP39ZG8H, VALUE TN 80, WITCONOL 2722, polyoxyethylene-sorbitan-20 mono-oleate, sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs, (Z)-, Montanox 80, Alkest TW 80, Tween 80, PS 80, E433, Polyoxyethylene Sorbitan Monooleate, Polyoxyethylene (20) Sorbitan Monooleate, Polyethylene Oxide Sorbitan Mono-Oleate Polysorbate 80, alkamuls PSML-80/100, crodalan AWS, emasol O-120V, glycosperse O-20, glycosperse O-20 KFG, 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl (E)-octadec-9-enoate, kaopan TW-O-120, liposorb O-20, lonzest SMO-20, monebatt - 80, mulsifan SMO-20, nikkol TO-10MV, nikkol TO-10V, norfox sorbo T-80, poe-20 sorbitan monooleate, polyoxyethylene (20) sorbitan monooleate, polysorbate 81, rheodol TW-O120V, toximul see-341, tween 80, Coco glucosides, CG, alkyl polyglycosides, alkyl C12-C14 polyglycosides, coconut glycosides, coco glucoside, palm kernel/Coco Glucoside, Glycol (polysorbate 80), PEG-3 Sorbitan oleate, PEG-6 Sorbitan oleate, Polyethylene glycol (3) sorbitan monooleate, Polyethylene glycol 300 sorbitan monooleate, Polyoxyethylene (20) sorbitan monooleate, Polyoxyethylene (3) sorbitan monooleate, Polyoxyethylene (5) sorbitan monooleate, Akamuls PSMO 20, Alkamuls T 80, Armotan PMO-20, Atlox 1087, Atlox 8916TF, Capmul POE-O, Cemerol T 80, Cemesol TW 1020, Crill 10, Crill 11, Crill S 10, Crillet 4, Crillet 4 Super, Crillet 41, Disponil SMO 120, Drewmulse POE-SMO, Durfax 80, Ecoteric T 80, Emasol O 105R, Emsorb 6900, Emulson 100M, Ethoxylated sorbitan monooleate, Eumulgin SMO 20, Flo Mo SMO 20, Glycols, polyethylene, ether with sorbitan monooleate, Glycosperse O 20, Glycosperse O 5, Glycosperse O-20, Glycosperse O-20 VEG, Glycosperse O-20X, Hodag SVO 9, MO 55F, Monitan, Montanox 80, Myvatex MSPS, Nikkol TO, Nikkol TO 10, Nikkol TO 10M, Nissan Nonion OT 221, Nonion OT 221, Olothorb, PEG sorbitan oleate, PEG-20 sorbitan oleate, Polisorbac 60, Polyethylene oxide sorbitan mono-oleate, Polyoxyethylene 20 sorbitan monooleate, Polyoxyethylene sorbitan monooleate, Polyoxyethylene sorbitan oleate, Polyoxyethylene(20) sorbitan monooleate, Polysorban 80, Polysorbate 80 B.P.C., Polysorbate 80 BPC, Polysorbate 80, U.S.P., Polysorbate 80, USP, Polysorbate 81, Protasorb O-20, Romulgin O, SVO 9, Sorbimacrogol oleate, Sorbimacrogol oleate 300, Sorbital 0 20, Sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl) derivatives, Sorbitan, monooleate, polyoxyethylene derivs, Sorbon T 80, Sorethytan (20) monooleate, Sorethytan oleate, Sorlate, TO 10, Tween 80, Tween 80 A, Tween 81, POLYSORBATE 80, PEG-20 SORBITAN OLEATE, POLYOXYETHYLENE SORBITAN MONOOLEATE, SORBITAN, MONO-9-OCTADECENOATE, POLY(OXY-1,2-ETHANEDIYL) DERIVS. (Z)-, PEG SORBITAN OLEATE, SORBITAN, MONOOLEATE, POLYOXYETHYLENE DERIVS., GLYCOLS, POLYETHYLENE, ETHER WITH SORBITAN MONOOLEATE, POLYOXYETHYLENE (20) SORBITAN MONOOLEATE, Tween 80, Polyoxyethylene 20 sorbitane molooleate, PEG 3 Sorbitane Oleate, Inhibited Ethylene Glycol, Inhibited ethylene glycol, antifreeze, Polysorbate 80, E 433, Tween 80, Polyoxyethylene (20) sorbitan monooleate, Polyoxyethylene sorbitan monooleate, Sorbitan monooleate ethoxylate, Polyoxyethylene sorbitan oleate, PEG sorbitan monooleate, Polyoxyethylene 20 sorbitan monooleate, E433, INS 433, PS 80, Alkest TW 80, Montanox 80, Kolliphor PS 80, Sorbax PMO-20, Polysorbata 80, Tween® 80
Polysorbate 80 is a surfactant and emulsifier used in cleaners and personal care products.
Polysorbate 80 is a nonionic surfactant and emulsifier often used in pharmaceuticals, foods, and cosmetics.
This synthetic compound, Polysorbate 80, is a viscous, water-soluble yellow liquid.
Polysorbate 80 is a synthetic compound with unique properties that make it valuable in various industries.
Polysorbate 80's CAS number is 9005-65-6, and its chemical formula is C64H124O26.
Polysorbate 80 is a nonionic surfactant belonging to the polysorbate class.
Polysorbate 80 is derived from the reaction of sorbitol with ethylene oxide, resulting in a polyoxyethylene chain attached to the sorbitol molecule.
The "80" in Polysorbate 80 represents the average number of moles of ethylene oxide used in the reaction.
Polysorbate 80 is a polyoxyethylene derivative of sorbitan and olive oil in the form of oleic acid.
Polysorbate 80 is a solubiliser and emuslifier.
Polysorbate 80 can solubilise carrier oils as well as essential oils and fragrances.
Polysorbate 80 is stable and non-toxic used in many household, cosmetic and pharmaceutical products.
Polysorbate 80 is a yellow in colour, with little scent.
Polysorbate 80 is the chemical name of a chemical known as Polysorbate 80 in INCI terminology.
Polysorbate 80's CAS number is 9005-65-6 .
Polysorbate 80 is used in industry primarily for its emulsifying properties.
Polysorbate 80 is formed by the ethoxylation of sorbitan.
Polysorbate 80 contains 80 sorbitan particles.
Ethylene oxide with a group of oleic acid attached to Polysorbate 80's hydrophobic tail.
Polysorbate 80 is yellow, Colored, water-soluble, viscous liquid.
Polysorbate 80 can be layered on top of each other.
Polysorbate 80 also ensures an even distribution of the product.
Polysorbate 80, also known as Tween 80, is a non-ionic detergent used for selective protein extraction and nuclear isolation from mammalian cell lines.
Polysorbate 80 is a key emulsifier that plays a crucial role in enhancing the texture, stability, and shelf life of food products.
Polysorbate 80 is a solubiliser, used to emulsify water-immiscible substances, such as fragrances, in water.
Mix this emulsifier with the fragrances or active ingredients to be emulsified in a ratio of approximately 4-6 parts of emulsifier to 1 part of substance to be emulsified.
This mixture is then miscible with water in any proportion.
Exactly how much emulsifier is needed differs per substance to be emulsified and must be found by trial and error, in some cases it can also be more than 6 parts.
For use in cosmetics do not use over 4 % Polysorbate 80 in stay on products (like cream and skin gels), for rinse off products je can go to 8%.
If you need more Polysorbate 80 is better to use Polysorbate 20.
For technical products like roomspray there is no maximum dosage, use as much as needed.
Polysorbates are a group of molecules commonly added to foods, pharmaceuticals, and cosmetics to improve consistency.
They are also commonly known under various brand names, such as Tween, Kolliphor, Scattics, Alkest, Canarcel, and Kotilen.
Overall, these molecules share the same basic structure of a hydrophilic group and a long hydrophobic tail (a fatty acid chain), making them amphiphilic.
Because of this, polysorbates are able to function as emulsifiers and surfactants in a variety of applications.
Polysorbate 80 exists as a viscous yellow liquid.
Polysorbate 80 is a synthetic compound.
Polysorbate 80 is a chemical substance with excipient properties.
Polysorbate 80 has nonionic surfactant properties.
Polysorbate 80 also has emulsifying properties.
Polysorbate 80 is a chemical substance belonging to the polyether class.
Polysorbate 80 is a polymer of ethylene oxide.
In polysorbate naming, Polysorbate 80 is indicated by the numerical designation following "polysorbate".
Polysorbate 80 is an emulsifier for use in cosmetics.
Polysorbate 80 is a versatile non-ionic surfactant and solubilising agent commonly used in cosmetic and personal care formulations to help disperse oils, fragrances, and essential oils into water-based products.
Polysorbate 80 is a nonionic emulsifier and surfactant and used in cosmetics and foods.
Polysorbate 80belongs to the class of non-ionic surfactant emulsifiers.
In the food industry, Polysorbate 80 functions as a stabilizer, emulsifier, and solvent for flavorings and colorants — particularly effective in oil-in-water mixtures.
Polysorbate 80 does not occur naturally — it is a fully synthetic compound, a mixture of partial sorbitan esters, its dianhydrides, and oleic acid.
Polysorbate 80 was developed in the first half of the 20th century as a derivative of polyethoxylated sorbitan esterified with food-grade oleic acid.
The industrial production of additive Polysorbate 80 is based on the ethoxylation of sorbitan followed by esterification.
Strict purity standards and controlled ethoxyl group content are maintained to minimize residual harmful impurities in the final product.
Physically, Polysorbate 80 is a viscous amber-yellow liquid, fully soluble in water and alcohols.
Polysorbate 80 is a surfactant which can also reduce bacterial attachment and inhibit biofilm formation.
Polysorbate 80 is an amber-colored viscous liquid.
Polysorbate 80 is a non-ionic surfactant and emulsifier often used in food and cosmetics.
The name "polyoxyethylene sorbitan monooleate" describes the structure of the molecule:
"Polyoxyethylene" refers to the presence of multiple (poly) units of oxyethylene in the molecule.
Oxyethylene is a chemical compound containing two hydrogen atoms and two oxygen atoms.
Polysorbate 80 is often used in the creation of surfactants, compounds that reduce the surface tension between two liquids or between a liquid and a solid.
"Sorbitan" is derived from sorbitol, a sugar alcohol that is often used as a sweetener and humectant (a substance that promotes moisture retention).
In the context of Polysorbate 80, sorbitan refers to dehydrated sorbitol which is used as the base molecule in the compound.
"Monooleate" indicates that there is an oleate (mono) group in the molecule.
An oleate is a salt or ester of oleic acid, a fatty acid that is naturally found in various animal and vegetable fats and oils.
Thus, Polysorbate 80 is a compound that consists of a dehydrated sorbitol (sorbitan) base with multiple oxyethylene units and a single oleate group.
Polysorbate 80 is a nonionic surfactant and emulsifier commonly used in food (with the European food additive number E433) and cosmetics mainly due to its ability to mix water-based and oil-based ingredients well (with a high approximate HLB value 15).
Polysorbate 80 is an emulsifier.
This non-toxic, FDA-approved surfactant, Polysorbate 80, is derived from sorbitol and oleic acid and is known for its ability to mix oil and water.
Polysorbate 80 liquid is a versatile, water-soluble emulsifier with a wide range of applications in the food, petroleum, chemical, plastics, machinery, paint, leather, cosmetics, and other industries.
Polysorbate 80 is an amber viscous liquid that is easily soluble in water, methanol, and ethanol, but insoluble in mineral oil.
The hydroxyl value of Polysorbate 80 is between 65 and 82, the saponification value is between 43 and 55, the acid value is less than or equal to 2, the moisture is less than or equal to 3, and the hydrophilic-lipophilic balance value is 15.
Polysorbate 80 is the most popular product in the polysorbate series.
Polysorbate 80 can be applied to various industries such as medicine, cosmetics, food, paint and pigment, textiles, and pesticides.
Polysorbate 80 is regarded as an emulsifier, dispersant, wetting agent, solubilizer and stabilizer.
Polysorbate 80 is present in some vaccines as either a stabilizer or as a residual manufacturing byproduct.
For example, polysorbate 80 can be found in lotions, makeup, shampoos and conditioners, medications (both oral and intravenous versions), vitamins and supplements, and foods.
Some common foods include salad dressings, canned foods, prepared foods and ice cream.
In ice cream, polysorbate 80 is used as an emulsifier to make the ice cream smooth and to slow its melting.
A typical serving of ice cream (1/2 cup) may contain about 170,000 micrograms* of polysorbate 80.
Raw material source of Polysorbate 80: sorbitol, vegetable oils
Production: Polysorbate 80 is obtained by esterifying sorbitol with one or three fatty acid molecules, including stearic, lauric, oleic, and palmitic acids.
Polysorbate 80 is an emulsifying agent consisting of sorbitol, ethylene oxide & oleic acid (polyoxyethylene-80 sorbitan monooleate), oleic acid is derived from vegetable oil.
Saponification value of Polysorbate 80 is 45-55.
HLB value of Polysorbate 80 is 15 (gives oil-in-water emulsions).
Polysorbate 80 is a non-ionic, multi-purpose emulsifier (enables water and oil to mix).
Emulsifying efficacy is increased when combined with cetyl alcohol or sorbitan stearate.
Polysorbate 80 acts as dispersing agent and anti-static thickener.
Polysorbate 80 is very useful as solubilizer and stabilizer of essential oils.
Polysorbate 80 may be useful as hair growth supplement.
USES and APPLICATIONS of POLYSORBATE 80:
In the food industry, polysorbate 80 is used in a variety of products such as ice cream, salad dressings, and baked goods.
Due to its ability to stabilize emulsions and increase the shelf life of products, Polysorbate 80 is an essential ingredient in many processed foods.
In cosmetic products, Polysorbate 80 is often used as a stabilizer, emulsifier, and thickener.
Polysorbate 80 can be found in products such as shampoo, body wash, and lotions.
Polysorbate 80 used in cosmetics is considered safe and has been approved by regulatory agencies such as the US Food and Drug Administration (FDA) and the European Union (EU).
Polysorbate 80 is used in the pharmaceutical industry as a solubilizing agent in medications and injectable drugs.
Polysorbate 80 improves the solubility of certain substances, making them more easily dispersed in liquid formulations.
Polysorbate 80, or tween 80, is the abbreviation of “polyoxyethylene sorbitan monooleate”, is a synthetic compound derived from the esterification of sorbitan with ethylene oxide.
Polysorbate 80 belongs to the polysorbate family of surfactants, which are widely used as emulsifiers, solubilizers, and stabilizers in various industries, including food, pharmaceuticals, cosmetics, and personal care products.
Polysorbate 80 used as emulsifier, stabiliser in a large range of foods including chewing gum, ice cream, soft drinks.
Polysorbate 80 is also used in a wide range of detergents, pharmaceuticals and beauty and skin products.
Polysorbate 80 is widely used as an emulsifier, stabilizer, and solubilizer due to its ability to form stable oil-in-water emulsions and increase the solubility of various substances.
Polysorbate 80 is often used in the formulation of pharmaceuticals, cosmetics, and personal care products, including creams, lotions, ointments, and oral solutions.
In the food industry, Polysorbate 80 is used as an emulsifier and dispersant in products such as dressings, sauces, baked goods, and ice cream.
Polysorbate 80 helps improve texture, prevent separation, and enhance flavor dispersion.
Polysorbate 80 is also regarded as a detergent.
Polysorbate 80 is an emulsifier derived from animal fatty acids, and natural oils and used as synthetic flavourings, surfactants, de foaming agents and dough conditioners.
Polysorbate 80 may increase the absorption of fat-soluble substances.
Polysorbate 80 is used as an emulsifier in food and some other products.
Areas of use of Polysorbate 80 as an emulsifier include: chocolates, breads, cake mixes, salad dressings, and the production of solid fats.
Surfactant properties are utilized in soap production and the cosmetics industry.
Polysorbate 80 is used as a lubricant in the manufacture of eye drops.
Polysorbate 80 is an emulsifier used in the production of vaccines and injection solutions to ensure a homogeneous distribution of the components within them.
Polysorbate is a chemical used as an excipient to stabilize aqueous drug formulations.
Polysorbate 80 is used as an adjuvant in influenza vaccines.
Estrogen has regulatory properties.
In some production processes, Polysorbate 80 helps compounds mix together.
Polysorbate 80 is a substance that prevents separation.
Polysorbate is used as a fixture to enhance fragrance longevity.
Polysorbate 80 is used to increase the solubility of the fragrance.
Polysorbate 80 is used in the manufacture of fever-reducing syrups along with the active ingredient.
Polysorbate 80's purpose here is to emulsify the substance.
Polysorbate 80 is used as an emulsifier in these types of shampoos.
Polysorbate 80 is used as an emulsifier in the manufacture of some pesticides.
In the cosmetics industry, Polysorbate 80 can help prevent bacterial and fungal growth in water-based cosmetic products.
This allows the resulting product to be safer for health.
Polysorbate 80 is used to help mix ice cream, chocolate sauces, and other sauces.
Polysorbate 80 is used in scabies cream formulations containing Benzyl Benzoate .
Polysorbate 80 can be used as an emulsifying agent in scabies cream manufacturing to ensure very good mixing of the water and oil phases.
In addition to cosmetic use, Polysorbate 80 is an excipient used to stabilize aqueous forms of medicinal products for parenteral administration or vaccination.
Polysorbate 80 helps prevent surface damage to a particle exposed to mechanical stress during transport and handling.
Polysorbate 80 is also one of the most commonly used surfactants in the formulation of protein-based biopharmaceuticals.
Polysorbate 80 is used as an emulsifier for pesticide formulations, primarily including EC, SL, EW, ME, WP, and WG formulations.
Polysorbate 80 is used as an emulsifier in emulsion explosives.
The textile industry uses Polysorbate 80 to soften fibers and improve the efficiency and productivity of the dyeing process.
Polysorbate 80 is also used in bath bombs and bath oils to help the oils disperse into the water.
Polysorbate 80 is used in formulations with a high amount of oils.
Additionally, Polysorbate 80 acts as a wetting agent or formulation stabilizer.
Polysorbate 80 is mainly used in the cosmetics, textile, and mining industries.
Polysorbate 80 is widely used in food, textiles, pharmaceuticals, and cosmetic products.
Polysorbate 80 is used as a surfactant, emulsifier, and solvent.
In cosmetic products, surfactants reduce surface tension between two surfaces.
Polysorbate 80's components are like two liquids or a liquid and a solid.
Polysorbate 80 has a special place.
The structure of a molecule that can hold both water-loving and oil-loving components.
Together, Polysorbate 80 attracts dirt, oil, and other foreign matter that accumulates on the surface.
Polysorbate 80 mixes with the skin and can be easily washed off with water.
Polysorbate 80 is mostly a combination of water-based and oil-based components.
Since emulsifiers can move widely, they are necessary to stabilize the formulation.
Polysorbate 80 helps to stabilize and act as a medium for both oil-loving and water-loving ingredients.
Polysorbate 80 is also used as a wetting agent and a dispersing agent.
Polysorbate 80 is used in the formulations of cleansers, creams, and lotions.
Polysorbate 80 is also used as a stabilizer and emulsifier.
The fatty acids in this detergent are of plant origin.
Polysorbate 80 is used in the food industry, pharmaceutical industry, and cosmetics manufacturing.
Polysorbate 80 is widely incorporated into sprays, cleansers, bath products, creams, and emulsified formulations to improve stability and product performance.
Uses of Polysorbate 80: Room & Body Sprays: 1–20%, Bath Oils: 1–20%, Cleansers & Face Washes: 0.5–5%, Creams & Lotions: 1–5%, Hair Care Products: 0.5–5%, Essential Oil Blends: As required, Bath Bombs & Bath Products: 0.5–5%.
Polysorbate 80 can be used as an emulsifier in creams, lotions and the like, but this is not common.
Polysorbate 80 is used as an emulsifier in various products, including food and cosmetics, to help mix oil and water components.
Polysorbate 80 is a compound that consists of a dehydrated sorbitol (sorbitan) base with multiple oxyethylene units and a single oleate group.
Polysorbate 80's used as an emulsifier in a variety of products, including food and cosmetics, to help mix oil and water components.
Common applications of Polysorbate 80: Chewing gum, refreshments, ice creams, pastry, pâtés, soups, alcoholic drinks
Polysorbate 80 is a hydrophilic and lipophilic nonionic surfactant made by ethoxylating sorbitan and oleic acid.
Polysorbate 80 is an amber-colored viscous liquid with a hydrophilic-lipophilic balance value of 15.
In addition, Polysorbate 80 is soluble in water, methanol, and ethanol, and insoluble in mineral oil.
Polysorbate 80 e433 is commonly used in various industries, including food, cosmetics, and pharmaceuticals, for its emulsifying, solubilizing, and stabilizing properties.
Polysorbate 80 is a yellowish liquid commonly used as an emulsifier, stabilizer, and dispersant in foods, including baked goods, dairy products, and confectionery.
In skincare, polysorbate 80 is a common ingredient in shampoos, conditioners, and other personal care products.
Polysorbate 80 helps products become smoother and less sticky, reduces the appearance of skin irritation, and enhances the effectiveness of some active ingredients.
One of the most popular uses of Polysorbate 80 liquid is in the production of baked goods.
This emulsifier, Polysorbate 80, is used to help improve the texture and consistency of products such as cake batters , bread doughs, and other baked goods.
Polysorbate 80 helps to mix ingredients more effectively, resulting in a smoother, more homogeneous dough .
Polysorbate 80, also commonly sold, is used in ice cream and other frozen desserts .
Polysorbate 80 helps prevent the formation of ice crystals, which can lead to a grainy or lumpy texture in the product.
Polysorbate 80 also helps improve the overall creaminess and mouthfeel of the ice cream, giving it a smoother, more luxurious texture.
Another common use of Polysorbate 80 in food is in the production of salad dressings and other sauces .
The polysorbate emulsifier, Polysorbate 80, helps prevent the separation of fat and water in these products, giving them a more stable and consistent texture.
Polysorbate 80 emulsifier also helps improve the overall mouthfeel of the sauce, making it more enjoyable to eat.
Polysorbate 80 helps bind oil and water together.
Polysorbate 80 belongs to the class of non-ionic emulsifiers.
Polysorbate 80 is also used in combination with an auxiliary emulsifier such as lecithin.
Due to its versatile and diverse properties, Polysorbate 80 is preferred in many sectors besides cosmetics.
In addition to its emulsifying properties, Polysorbate 80 is also used as a solvent.
Polysorbate 80's common applications include shampoos, body washes, lotions, creams, and bath bombs.
Polysorbate 80 is preferred in the production of bath bombs.
Polysorbate 80 prevents oils and paint from sticking to the bathtub.
Polysorbate 80 is also preferred in hair care products to increase spreadability.
In addition, Polysorbate 80 finds application in products such as eyeshadow and lipstick as it helps in the even distribution of pigments.
Furthermore, Polysorbate 80 is an excellent solvent for essential oils, wetting agents, viscosity modifiers, stabilizers, and dispersing agents individually.
Polysorbate 80 is a commonly used emulsifier and solvent in skincare and cosmetic products.
Applications of Polysorbate 80: Body washes, hair shampoos, hair loss treatments, lotions, creams, bath oils, solvents.
Applications of Polysorbate 80: Body washes, hair shampoos, hair loss treatments, lotions, creams, bath oils, solubilizates.
-Polysorbate 80 In Cosmetic:
Polysorbate 80 or Tween 80, is a versatile ingredient widely used in cosmetic and personal care products for its emulsifying, solubilizing, and stabilizing properties.
As an emulsifier, Polysorbate 80 facilitates the blending of oil and water-based ingredients, ensuring stable and uniform formulations in products like creams, lotions, and serums.
Additionally, Polysorbate 80 serves as a solubilizing agent, enabling the incorporation of hydrophobic substances into aqueous solutions, thus enhancing the overall solubility and efficacy of cosmetic products.
Polysorbate 80's role in texture enhancement contributes to the luxurious consistency of formulations, providing consumers with a smooth and pleasant sensory experience.
Furthermore, Polysorbate 80 plays a crucial role in stabilizing cosmetic formulations, preventing ingredient separation and maintaining product integrity over time, thereby extending shelf life and ensuring efficacy.
Commonly found in various skin care and hair care products, Polysorbate 80 enhances the performance of these formulations, contributing to their effectiveness and consumer satisfaction.
-Pharmaceutical Industry uses of Polysorbate 80:
Polysorbate 80 is widely used as an excipient in pharmaceutical formulations.
Polysorbate 80 stabilizes proteins and biologics, prevents precipitation, and improves drug solubility.
Polysorbate 80 is frequently used in injectable medications, vaccines, ophthalmic products, creams, ointments, capsules, and emulsions.
In biotechnology and vaccine formulations, Polysorbate 80 helps stabilize sensitive proteins during manufacturing, transportation, and storage.
-Food use of Polysorbate 80:
Polysorbate 80 is used as an emulsifier in foods.
For example, in ice cream, Polysorbate 80 is added up to 0.5 % (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing its resistance to melting.
Adding Polysorbate 80 prevents milk proteins from completely coating the fat droplets.
This allows them to join together in chains and nets, which hold air in the mixture, and provide a firmer texture that holds Polysorbate 80's shape as the ice cream melts.
-Health and beauty uses of Polysorbate 80:
Polysorbate 80 is also used as a surfactant in soaps and cosmetics (including eyedrops), or a solubilizer, such as in a mouthwash.
The cosmetic grade of Polysorbate 80 may have more impurities than the food grade.
-Medical uses of Polysorbate 80:
Polysorbate 80 is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products.
Polysorbate 80 is also an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone.
Polysorbate 80 is also used as an excipient in some European and Canadian influenza vaccines.
Influenza vaccines contain 2.5 μg of Polysorbate 80 per dose.
Polysorbate 80 is found in many vaccines used in the United States, including the Janssen COVID-19 vaccine.
Polysorbate 80 is used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth.
Polysorbate 80 is also used as an emulsifier in the estrogen-regulating drug Estrasorb.
Polysorbate 80 is also used in granulation for stabilization of drugs and excipients when IPA binding.
-Polysorbate 80 In Pharmaceutical:
Polysorbate 80 is a key ingredient in the pharmaceutical industry due to its versatile properties.
Acting as a solubilizing agent, Polysorbate 80 enhances the solubility of poorly water-soluble drugs, improving their bioavailability and efficacy.
Additionally, Polysorbate 80 serves as an emulsifier, ensuring the uniform dispersion of oil and water-based ingredients in formulations like suspensions and ointments.
Polysorbate 80's stabilizing effects prevent particle aggregation and maintain formulation integrity, extending shelf life.
Furthermore, Polysorbate 80 plays a vital role in drug delivery systems, facilitating drug penetration and absorption.
Its versatility and compatibility make Polysorbate 80 an essential excipient in various dosage forms, from oral medications to topical creams, contributing to the effectiveness and reliability of pharmaceutical products.
-Laboratory uses of Polysorbate 80:
Some mycobacteria contain a type of lipase (enzyme that breaks up lipid molecules).
When these species are added to a mixture of polysorbate 80 and phenol red, they break down polysorbate 80 and cause the solution to change color, so this is used as a test to identify the phenotype of a strain or isolate.
On RODAC agar plates used in microbiological control, polysorbate 80 counteracts disinfectants often found on sampled surfaces, thereby allowing the microbes found on these surfaces to grow
Sorbitol is an emulsifying agent composed of ethylene oxide and oleic acid (polyoxyethylene-80 sorbitan monooleate); oleic acid is obtained from vegetable oil.
-In The Foam Industry uses of Polysorbate 80:
Polysorbate 80 is a nonionic surfactant widely used in foam production.
E433 polysorbate 80 is used as a stabilizer and co-foaming agent in the production of polyurethane foam.
Polysorbate 80 emulsifier has significant electrolyte resistance and can effectively reduce foam surface tension and improve foam stability, thereby enhancing foam performance and quality.
WHAT POLYSORBATE 80 IS USED FOR AND WHERE?
Cosmetics
Polysorbate 80 is used as a surfactant, stabilizer and emulsifier in the composition of cosmetics and has these INCI functions:
Denaturant.
The ionic or polar molecules of Polysorbate 80 included in formulations that interact with protein groups, modulate the properties of the solution to suit specific needs.
Surfactant - Cleansing agent.
Cosmetic products used to cleanse the skin utilise the surface-active action that produces a lowering of the surface tension of the stratum corneum, facilitating the removal of dirt and impurities.
Surfactant - Emulsifying agent.
Emulsions are thermodynamically unstable and are used to soothe or soften the skin and emulsify, so they need a specific, stabilising ingredient.
Polysorbate 80 forms a film, lowers the surface tension and makes two immiscible liquids miscible.
A very important factor affecting the stability of the emulsion is the amount of the emulsifying agent.
Emulsifiers have the property of reducing the oil/water or water/oil interfacial tension, improving the stability of the emulsion and also directly influencing the stability, sensory properties and surface tension of sunscreens by modulating the filmometric performance.
Food
Ingredient included in the list of European food additives such as E433 with emulsifier function and with name
FUNCTION AND APPLICATION of POLYSORBATE 80:
Polysorbate 80 is soluble in water, methanol, ethanol, insoluble in mineral oil, used as emulsifier, dispersant, wetting agent, solvent, stabilizer, used in medicine, cosmetics, food and other industries.
Polysorbate 80 is used as stabilizer and foaming aid in the production of polyurethane foam;It can be used as antistatic agent in synthetic fiber and intermediate of chemical fiber oil agent.
Polysorbate 80 is used as wetting agent and dispersant in film making of photosensitive materials;In the process of fabric waterproofing to emulsify silicone oil, has a good effect, also used in nylon and viscose cord as oil agent and water-soluble emulsifier, often mixed with s-80.
Polysorbate 80 is used as oil field emulsifier, wax-preventing agent, heavy oil wetting agent, drag reducing agent, and near-well zone treatment agent;Used as precision machine tool to modulate lubrication coolant, etc.
WHAT ARE POLYSORBATE 80 USES?
Polysorbate 80 is a versatile compound product with numerous uses across various industries.
Commonly used in food, cosmetic and pharmaceutical.
Polysorbate 80 in Food
Dairy Products:
Ice cream and frozen desserts:
Polysorbate 80 is often used as an emulsifier to improve the texture and prevent ice crystallization in ice cream and frozen desserts.
Processed cheeses:
Polysorbate 80 may be added to processed cheese products to enhance their meltability and texture.
Baked Goods:
Bread and baked goods:
Polysorbate 80 can be found in certain types of bread and baked goods to improve their texture and shelf life.
Cake mixes and frosting:
Polysorbate 80 may be added to cake mixes and frosting to improve their consistency and stability.
Sauces and Dressings:
Salad dressings: Polysorbate 80 is commonly used as an emulsifier in salad dressings to prevent separation and achieve a smooth texture.
Sauces and gravies:
Polysorbate 80 may be added to sauces and gravies to improve their texture and stability.
Confectionery:
Chocolate and candy coatings:
Polysorbate 80 is sometimes used in chocolate and candy coatings to improve their flow properties and prevent blooming.
Chewing gum:
Polysorbate 80may be added to chewing gum to enhance its texture and consistency.
Processed Meats:
Processed meats:
Polysorbate 80 can be found in certain processed meat products, such as sausages and luncheon meats, to improve their texture and moisture retention.
Other Processed Foods:
Instant noodles:
Polysorbate 80 may be added to instant noodle products to prevent the noodles from sticking together and improve their texture.
Margarine and spreads:
Polysorbate 80 may be used in margarine and spreads to achieve a smooth and spreadable consistency.
FEATURES of POLYSORBATE 80:
Emulsifying agent:
Polysorbate 80 liquid is used to mix oils and water-based components into a homogeneous mixture.
This is a crucial function in food production as Polysorbate 80 helps improve the texture, appearance, and flavor of specific products.
Stabilizer:
Polysorbate 80 emulsifier is also used as a stabilizer to prevent the separation or precipitation of components in food products.
This is especially important in products with high fat content, as Polysorbate 80 helps the fat to be distributed evenly throughout the product.
Foaming agent:
Polysorbate 80 can also be used as a foaming agent in some food products such as whipped cream or meringue.
Polysorbate 80 helps create stable foam with a long-lasting and smooth texture.
Texturizing Agent:
Polysorbate 80 in foods can be used as a texturizing agent to give food a smooth and creamy texture.
This is especially important in products like ice cream or pudding where texture is a significant factor in consumer satisfaction.
BENEFITS of POLYSORBATE 80:
Polysorbate 80 is non-ionic, multi-purpose emulsifier (allows water and oil to mix)
When combined with cetyl alcohol or sorbitan stearate, Polysorbate 80's emulsifying activity increases.
Polysorbate 80 acts as a dispersing agent and an anti-static thickener.
Polysorbate 80 is very useful as a solubilizer and stabilizer for essential oils.
Polysorbate 80 can be useful as a hair growth supplement.
FEATURES of POLYSORBATE 80:
Polysorbate 80 is important to note that while Tween 80 is generally considered safe for consumption and topical use, it is recommended to follow the guidelines and regulations set by the relevant authorities and adhere to the specified usage levels for each use.
PHYSICAL CHARACTERISTICS of POLYSORBATE 80:
Appearance: Yellow to amber color, semi-solid.
Taste: Warm and slightly bitter.
Density: 1.08 g/mL
Boiling Point: >100 °C
Solubility: Soluble in water, ethanol, ethyl acetate, and toluene; insoluble in fats.
Stability: Incompatible with strong alkaline and oxidizing chemicals.
The CAS number for Polysorbate 80 (E433) is 9005-65-6.
FUNCTIONS of POLYSORBATE 80:
In cosmetics and personal care products, polysorbate 80 functions as a surfactant, emulsifier, and solubilizer.
Polysorbate 80 is a nonionic surfactant, which means it has a neutral charge.
Polysorbate 80 is a surfactant, or surface active agent, works by lowering the surface tension between two substances, such as two liquids or a liquid and a solid.
Polysorbate 80 is a surfactant molecule contains one end that is hydrophilic (attracted to water) and one end that is lipophilic (attracted to oil).
This allows surfactants to attract and suspends oils, dirt, and other impurities that have accumulated on the skin and wash them away.
Due to these properties, polysorbate 80 can be found in many different cleansers and body washes.
Polysorbate 80 is also an emulsifier with an HLB value of 15.
HLB (Hydrophile-Lipophile Balance) is an empirical expression for the relationship of the hydrophilic and lipophilic groups of a surfactant.
An HLB of greater than 10 means that the substance is soluble in water.
As an emulsifier, polysorbate 80 is often used in formulations that contain both water and oil components.
Mixing water and oil together creates a dispersion of oil droplets in water (and vice versa).
However, these two phases can separate if the product is left to settle.
To address this problem, an emulsifier like polysorbate 80 can be added to the system to help the droplets remain dispersed.
Emulsifiers improve the consistency of a product, which enables an even distribution of topical skin care benefits.
Polysorbate 80 also functions as a solubilizer with a wide range of hydrophilic characteristics.
Polysorbate 80 can be used individually, or in combination with a variety of other hydrophobic emulsifiers, to produce many different types of oil-in-water, and water-in-oil emulsion systems.
When used alone, polysorbate 80 is an excellent solubilizer for essential oils and has good function as a wetting agent, viscosity modifier, anti-static agent, stabilizer, and dispersing agent.
Polysorbate 80 can also improve the rinse off of anhydrous scrubs and cleansing oils.
HOW IS POLYSORBATE 80 PRODUCED?
High-purity polysorbate is obtained through the esterification reaction of sorbitol and ethylene oxide.
Another acid used in its production is oleic acid.
Oleic acid is both an animal and plant fatty acid.
However, commercially available oleic acid is not a pure fatty acid; Polysorbate 80 is a mixture of different fatty acids.
The production reaction for Polysorbate 80 is as follows.
Commercial production techniques typically consist of three stages.
These are:
Sorbil Alcohol (Sorbitol) dehydration
Esterification of Oleic Acid
Etherification of Oxytetane
WHAT IS POLYSORBATE 80 PHYSICAL AND CHEMICAL PROPERTIES?
Polysorbate 80 has a color between yellow and amber.
Polysorbate 80 has a warm and bitter taste.
Polysorbate 80's density is 1.08 g/mL.
Polysorbate 80's boiling point is above 100 °C.
Polysorbate 80's melting point is -6 °C.
Polysorbate 80 is incompatible with strong alkaline chemicals and oxidizing agents in terms of stability.
Polysorbate 80 is soluble in water and alcohol.
Polysorbate 80 is insoluble in oil.
GENERAL CHARACTERISTICS of POLYSORBATE 80:
Ethoxylated sorbitan monooleate is a hydrophilic, non-ionic surfactant.
Polysorbate 80 is a thick yellow liquid characterized by high viscosity.
Polysorbate 80 is very soluble in water, soluble in low aliphatic alcohols and benzene, and poorly soluble in fats.
Polysorbate 80 is biodegradable in the natural environment.
Polysorbate 80 is produced by the ethoxylation of a molecule called sorbitan.
Sorbitan is the dehydrated form of sorbitol, a sugar alcohol that occurs naturally in some fruits.
Ethoxylation is a chemical reaction that adds ethylene oxide to a substrate, in this case sorbitan.
Sorbitan reacts with 80 units of ethylene oxide, hence the name "80".
Polysorbate 80 can be of plant or animal origin.
The fatty acids directly involved in Polysorbate 80's production are obtained, for example, from olive oil or animal products.
PROPERTIES OF POLYSORBATE 80 IN COSMETIC PRODUCTS
Polysorbate 80 is a skin care ingredient used in cosmetics and personal care products to improve their texture.
Polysorbate 80 gives cosmetics a smooth consistency.
While the texture of the product is primarily sensory, Polysorbate 80 is also important that it spreads easily.
Polysorbate 80 effectively supports the stability of creams, lotions, and gels, especially cold-processed ones, promoting the easy binding of oils and water.
Polysorbate 80 is used as a surfactant, emulsifier, and solvent, helping to create a smooth, easy-to-apply finish in skin and body care products.
As an emulsifier, Polysorbate 80 helps to mix components and prevents their separation.
Polysorbate 80's solubility properties are used in cosmetic preparations.
As a surfactant, Polysorbate 80 increases the solubility of one substance in another.
A substance that would not normally dissolve in a given solution may dissolve in the presence of Polysorbate 80.
This makes Polysorbate 80 effective, for example, for washing away dirt from the skin surface with facial cleansing gels containing ethoxylated sorbitan monooleate.
THE FUNCTIONS OF POLYSORBATE 80 IN COSMETIC PRODUCTS
*emulsifier,
*solvent,
*distributor,
*stabilizing factor.
Products containing Polysorbate 80 include: shampoos, shower gels, moisturizing creams, facial cleansers, after-sun creams, body lotions, foot creams, cleansing milks, liquid soaps, face creams, etc.
SYNTHESIS PROCESS of POLYSORBATE 80:
The synthesis process takes place in several stages.
Step 1:
Preparation of raw materials: sorbitol, ethylene oxide and oleic acid.
Step 2: Ethoxylation.
Sorbitol reacts with ethylene oxide in a process that involves the addition of ethylene oxide to the sorbitol molecule, creating a series of repeated ethylene oxide units.
Step 3: Esterification.
Sorbitol ethoxylate is reacted with oleic acid and involves the formation of an ester bond between sorbitol ethoxylate and oleic acid, creating the final molecule Polysorbate 80.
WHAT IS POLYSORBATE 80 AND WHAT IS IT USED FOR?
Polysorbate 80 is an emulsifier used in pharmaceuticals and food preparation.
Polysorbate 80 is particularly widely used in the cosmetics industry.
One of Polysorbate 80's most important functions is to create a bond between water-based and oil-based components, allowing them to mix and combine.
Polysorbate 80 is preferred in creams, lotions, serums, and makeup formulas to ensure proper distribution of components.
However, polysorbate 80 is also used in cosmetics to convert essential and fixed oils into water-based products.
Polysorbate 80 is also a safe, non-ionic emulsifier.
USAGE of POLYSORBATE 80:
Polysorbate 80 can be added to formulas as is.
Typical usage level of Polysorbate 80 is 1-10%.
Polysorbate 80 is used for external use only.
BENEFITS of POLYSORBATE 80:
Polysorbate 80 is not a natural component of the human body and does not provide any direct health benefits.
In pharmaceuticals, Polysorbate 80 is used as a solvent and stabilizer, enhancing the bioavailability of active ingredients.
Polysorbate 80 is a nonionic emulsifier and surfactant and used in cosmetics and foods.
CHARACTERISTICS of POLYSORBATE 80:
Polysorbate 80 has excellent emulsifying and dispersing capabilities.
Because Polysorbate 80 contains both hydrophilic and lipophilic groups, it can stabilize mixtures containing oils, waxes, fragrances, vitamins, and active pharmaceutical ingredients.
Polysorbate 80 is highly valued for its mildness, relatively low toxicity, and broad compatibility with cosmetic and pharmaceutical ingredients.
Polysorbate 80 also improves texture, consistency, and shelf stability in many products.
One important characteristic is Polysorbate 80's ability to solubilize hydrophobic compounds in aqueous systems.
This makes Polysorbate 80 useful in injectable drugs, vaccines, creams, lotions, beverages, and biotechnology formulations.
Polysorbate 80 also reduces interfacial tension, improves wetting properties, and prevents aggregation of proteins in biopharmaceutical products.
PROPERTIES of POLYSORBATE 80:
Polysorbate 80 is a colourless to light yellow viscous liquid at room temperature, the substance has a fairly long shelf life.
Polysorbate 80 can make certain preservatives, such as parabens, less effective, we indicate this as well as possible in the description of our preservatives.
Occasionally, a black powdery or stringy precipitate forms at the bottom of a package.
This is normal and no problem, possibly stir well before use.
SUSTAINABILITY of POLYSORBATE 80:
Polysorbate 80 is largely made from renewable plant materials and partly from fossil fuels.
Polysorbate 80 is degradable in the environment.
Polysorbate 80 is a nonionic surfactant and emulsifying agent widely used in the pharmaceutical, cosmetic, food, biotechnology, and chemical industries.
Polysorbate 80 is produced by the ethoxylation of sorbitan monooleate, which is derived from sorbitol and oleic acid.
Because of its amphiphilic structure, Polysorbate 80 can interact with both water and oil phases, allowing stable emulsions and dispersions to form.
Polysorbate 80 is commonly used as a stabilizer, wetting agent, dispersing agent, solubilizer, lubricant, and emulsifier.
Polysorbate 80 is especially important in formulations where oil and water ingredients must remain uniformly mixed over long storage periods.
Polysorbate 80 is generally recognized as safe for approved uses in foods, cosmetics, and pharmaceutical preparations when used within regulatory limits.
KEY PROPERTIES AND STRUCTURAL CHARACTERISTICS of POLYSORBATE 80:
Here are some of its key properties and structural characteristics:
Hydrophilic-Lipophilic Balance (HLB) :
Polysorbate 80 has a moderate HLB value, typically ranging from 15 to 16.
This balance of hydrophilicity and lipophilicity allows Polysorbate 80 to act as an effective emulsifier, facilitating the formation of stable oil-in-water emulsions.
Emulsifying Properties:
As an emulsifier, Polysorbate 80 lowers the interfacial tension between oil and water phases, allowing them to mix more easily and form stable emulsions.
Polysorbate 80 accomplishes this by adsorbing to the interface between the two phases, with its hydrophilic head facing the water phase and its lipophilic tail facing the oil phase.
Solubilizing Ability:
Polysorbate 80 exhibits solubilizing properties, enabling it to dissolve hydrophobic (water-insoluble) substances in aqueous solutions.
This makes Polysorbate 80 useful in pharmaceutical formulations for improving the solubility and bioavailability of poorly water-soluble drugs.
Stabilizing Effect:
In addition to its emulsifying and solubilizing properties, Polysorbate 80 acts as a stabilizer in formulations, preventing the aggregation or precipitation of particles and enhancing the stability of suspensions and emulsions over time.
Compatibility:
Polysorbate 80 is compatible with a wide range of other ingredients, including oils, surfactants, and hydrophilic and hydrophobic substances.
This compatibility makes Polysorbate 80 versatile and allows for its incorporation into diverse formulations across multiple industries.
PROPERTIES of POLYSORBATE 80:
Effective solubilising and dispersing agent
Polysorbate 80 helps blend oils into water-based formulations
Supports stable emulsions and mixtures
Polysorbate 80 improves formulation clarity and consistency
Mild and versatile ingredient
Compatible with a wide range of cosmetic ingredients
Easy to incorporate into formulations
WHAT IS POLYSORBATE 80 AND WHAT IS IT USED FOR?
Polysorbate 80 is an emulsifying agent.
Polysorbate 80 is a surfactant.
Polysorbate 80 can be used in conjunction with a co-emulsifier such as lecithin to coat oil-in-water and oil-in-water emulsion systems .
Polysorbate 80 is an excellent solvent for viscosity modifiers, stabilizers, and dispersants.
Polysorbate 80 is both a thickener and a viscosity regulator.
WHAT IS THE PERCENTAGE OF SORBITAN MONOOLEATE IN POLYSORBATE 80?
Polysorbate 80 consists of Sorbitan Monooleate (Span 80) and Polyoxyethylene (PEG).
Sorbitan typically makes up 60–80% of the composition, with the remainder being polyethylene glycol (PEG).
This combination provides Polysorbate 80's emulsifying properties.
WHAT ARE THE TEMPERATURE AND PRESSURE CONDITIONS FOR USING POLYSORBATE 80?
The optimal temperature for dissolving Polysorbate 80 is typically between 40°C and 70°C to ensure even dissolution and effective emulsification.
For most food applications, normal pressure is sufficient unless a specific production process requires higher pressure.
High-pressure conditions are not necessary for typical food formulations.
WHAT IS THE DENSITY OF POLYSORBATE 80?
The density of Polysorbate 80 is approximately 1.06 g/cm³.
This value may vary slightly depending on temperature, but generally remains within this range.
Polysorbate 80 (Span 80), the primary component of Tween 80, also has a similar density of approximately 1.04–1.06 g/cm³.
WHAT IS THE VISCOSITY OF POLYSORBATE 80?
Polysorbate 80 typically has a viscosity of 300–800 at room temperature (20°C), meaning it is quite viscous in its concentrated form.
Viscosity will decrease with increasing temperature.
When heated to approximately 60°C or higher, the viscosity of Polysorbate 80 decreases significantly, making it more fluid.
Polysorbate 80 has a similar viscosity.
WHAT IS THE PRODUCTION METHOD FOR POLYSORBATE 80?
The production method for Polysorbate 80 consists of two main steps:
Synthesis of Sorbitan Esters:
Sorbitol reacts with fatty acids such as oleic acid (from castor oil) to form Sorbitan Monooleate (SPAN 80) .
Polyoxyethylenetion:
SPAN 80 is then reacted with ethylene oxide (EO) to produce Polyoxyethylene Sorbitan Monooleate, forming Polysorbate 80.
Purification:
Polysorbate 80 undergoes filtration, refining, and drying processes to remove impurities and ensure food-grade quality.
WHAT IS THE HLB VALUE OF POLYSORBATE 80?
Polysorbate 80 has an HLB (Hydrophilic-Lipophilic Balance) value of approximately 15, indicating that it is a highly hydrophilic (water-loving) emulsifier.
This makes Polysorbate 80 suitable for the formation of oil-in-water (O/W) emulsions where water is the continuous phase.
Emulsifying agent consisting of sorbitol, ethylene oxide & oleic acid (polyoxyethylene-80 sorbitan monooleate), oleic acid is derived from vegetable oil.
Saponification value 45-55.
HLB value 15 (gives oil-in-water emulsions).
BENEFITS of POLYSORBATE 80:
Non-ionic, multi-purpose emulsifier (enables water and oil to mix)
Emulsifying efficacy is increased when combined with cetyl alcohol or sorbitan stearate
Polysorbate 80 acts as dispersing agent and anti-static thickener
Very useful as solubilizer and stabilizer of essential oils
Polysorbate 80 may be useful as hair growth supplement
WHAT IS THE COMPOSITION OF POLYSORBATE 80?
The main components of Polysorbate 80 are:
Sorbitan Monooleate (SPAN 80): Approximately 60-80%.
Polyoxyethylene (20) Sorbitan Monooleate: Approximately 20-40%.
This composition allows Polysorbate 80 to act effectively as an emulsifier and stabilizer, providing smooth textures and preventing phase separation in food products.
DOES POLYSORBATE 80 CONTAIN GLUTEN AS A RAW MATERIAL?
No, Polysorbate 80 is gluten-free.
The gluten potential of Tween 80 depends on the source of the oleic acid used in its production.
If the oleic acid is derived from rice oil, there may be a small risk of gluten contamination.
USAGE RATES OF POLYSORBATE 80:
Polysorbate 80 may vary depending on the product type.
Facial serums and toners: 1% – 3%
Lotions and creams: 2% – 5%
In makeup removers and oil-based products: 3% - 10%
In hair care products: 1% - 5%
In bath and shower products: 1% - 10%
These concentrations can be adjusted according to the formulation and desired texture.
Lower doses are recommended for sensitive skin.
WHAT ARE 80 (AFTER POLYSORBATE) AND 20 (FOLLOWING POLYOXYETHYLENE) STANDS FOR?
80 refers to the type of fatty acid attached to the polyoxyethylene sorbitan part of the molecule, here it is monooleate or oleic acid.
20 means the total number of oxyethylene –(CH2CH2O)–groups in the molecule.
HOW IS POLYSORBATE 80 MADE?
Polysorbates (20,40, 60, 65, 80) are the ethoxylated sorbitan esters which are manufactured by the reaction among sorbitol, a specific fatty acid, and ethylene oxide (an average of 20 polymerized ethylene oxide per molecule of polysorbate 80).
The fatty acid used for the production of polysorbate 80 is oleic acid.
Let’s see its two raw materials.
Sorbitol
It is a sugar alcohol produced by the reduction reaction (or hydrogenation) of glucose which is obtained from maize or tapioca starch.
Oleic Acid
Oleic acid is a monounsaturated fatty acid naturally found in animal fats & oils and vegetable oils.
Commercial food grade oleic acid is not pure and is a mixture of several fatty acids.
Like other fatty acids, oleic acid also present in nature commonly in the form of triglycerides.
The following are the vegetable oils high with oleic acid:
Olive oil
Pecan oil
Canola oil
Peanut oil
Macadamia oil
Sunflower oil
Grape seed oil
Sea buckthorn oil
Sesame oil
Poppyseed oil
Manufacturing process
According to the FDA, there are generally two steps in the manufacturing process of polysorbate 80:
Esterification between oleic acid and sorbitol to obtain sorbitan esters.
Condensation sorbitan esters with ethylene oxide.
Polysorbate 80 can also be produced by reacting sorbitol and ethylene oxide first then esterified with oleic acid, the following are the brief flow chart:
Obtaining the mixture of sorbitol and sorbitan by partially dehydrating sorbitol.
Adding ethylene oxide to the mixture to obtain sorbitan polyethylene ether.
Reacting it with oleic acid.
PROPERTIES of POLYSORBATE 80:
Appearance
Polysorbate 80 is a viscous, lemon to amber-colored oily liquid at 25°C.
Hydrophilic
Lipophilic Balance (HLB) 15, gives oil-in-water emulsions, O/W
Viscosity
Polysorbate 80 is also a viscosity agent with the viscosity 300–500 centistokes (@25°C).
Solubility
In Water
Polysorbate 80 is soluble in water due to the long polyoxyethylene chains.
In Organic Solvents
Polysorbate 80 is soluble in most solvents, such as ethanol, methanol, ethyl acetate and toluene.
Synthetic food additive with emulsifying and flavoring role.
Polysorbate 80 is also used as a solvent for other food additives.
Polysorbate 80 is used in fine bakery products, sauces, desserts, confectioneries, fat emulsions for pastry, instant soups, ice, dietetic foods for body weight control.
Polysorbate 80 is not recommended for vegetarians, because it can come from animal fats.
HOW IS POLYSORBATE 80 MADE?
Polysorbate 80 is synthesized through a chemical reaction involving sorbitan monostearate and ethylene oxide.
Here's an overview of the process:
Starting Materials
The primary starting material for the synthesis of Polysorbate 80 is sorbitan monostearate, which is derived from sorbitol, a sugar alcohol.
Sorbitan monostearate is a fatty acid ester with a hydrophilic (water-attracting) sorbitan head and a lipophilic (oil-attracting) stearate tail.
Ethoxylation
Sorbitan monostearate undergoes a process called ethoxylation, which involves the addition of ethylene oxide molecules to the molecule.
Ethylene oxide is a reactive compound that reacts readily with the hydroxyl groups present in sorbitan monostearate.
Polymerization
As ethylene oxide molecules react with sorbitan monostearate, they form chains of repeating ethylene oxide units, leading to the formation of a polyethylene glycol (PEG) chain.
This polymerization process results in the formation of Polysorbate 80, which is a mixture of sorbitan monoester ethoxylates with varying degrees of ethoxylation.
Purification
After the synthesis, the crude Polysorbate 80 product undergoes purification steps to remove impurities and by-products.
This may involve processes such as filtration, distillation, or chromatography to ensure the final product meets quality standards and regulatory requirements.
Packaging and Distribution
Once purified, the Polysorbate 80 is typically packaged into containers suitable for transportation and distribution to manufacturers in various industries, including food, pharmaceuticals, cosmetics, and personal care products.
In short, the synthesis of Polysorbate 80 involves the ethoxylation of sorbitan monostearate, resulting in the formation of a polyethylene glycol chain attached to the sorbitan molecule.
This process yields a versatile emulsifier with a wide range of applications across different sectors.
WHAT IS POLYSORBATE 80 USED FOR?
Polysorbate 80 is widely used in various industries, including cosmetics, due to its versatile properties and benefits.
Polysorbate 80 serves as an effective emulsifier and solubilizer, allowing for the blending of water and oil-based ingredients in cosmetic formulations.
This makes Polysorbate 80 valuable in creating stable emulsions, such as creams, lotions, and serums, ensuring proper dispersion of active ingredients.
Polysorbate 80 is also utilized in haircare products to enhance the spreadability and distribution of conditioning agents.
In addition, Polysorbate 80 finds applications in cosmetic products like foundations, eyeshadows, and lipsticks, where it aids in the uniform dispersion of pigments, resulting in smooth and consistent application.
ORIGIN OF POLYSORBATE 80:
Polysorbate 80 is produced through the ethoxylation process, where sorbitol, a sugar alcohol derived from natural sources, is reacted with ethylene oxide.
This reaction creates a polyethylene glycol chain attached to the sorbitol molecule, resulting in the formation of Polysorbate 80.
WHAT DOES POLYSORBATE 80 DO IN A FORMULATION?
*Emulsifying
*Surfactant
SAFETY PROFILE OF POLYSORBATE 80:
Polysorbate 80 is generally considered safe for use in cosmetics.
Polysorbate 80 is not considered toxic when used in recommended concentrations.
However, some individuals with sensitive skin may experience mild skin irritation, therefore, a patch test is necessary.
Further, Polysorbate 80 is generally considered vegan as it is derived from natural sources and does not contain animal-derived ingredients.
ALTERNATIVES OF POLYSORBATE 80:
*POLYSORBATE 20,
*CETEARETH20,
*GLYCERYL STEARATE
CLASS OF POLYSORBATE 80:
*Emulsifiers,
*Stabilisers,
*Thickeners,
*Gelling Agents,
CHEMISTRY OF POLYSORBATE 80:
Polysorbate 80 is derived from polyethoxylated sorbitan and oleic acid.
The hydrophilic groups in Polysorbate 80 are polyethers also known as polyoxyethylene groups, which are polymers of ethylene oxide.
In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case, the oleic acid (see polysorbate for more detail).
The full chemical names for Polysorbate 80 are:
Polyoxyethylene (80) sorbitan monooleate
(x)-sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl)
The critical micelle concentration of Polysorbate 80 in pure water is reported as 0.012 mM.
IS POLYSORBATE 80 SAFE TO EAT?
Yes, Polysorbate 80 has been approved as a safe ingredient by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).
FDA
Polysorbate 80 is a multifunctional ingredient that may be safely used in food as an emulsifier, defoamer, solubilizing and dispersing agent, surfactant, wetting agent and adjuvant.
The following food may contain it and with the maximum use levels:
*Ice cream 0.1%
*Yeast defoamer 4ppm
*Pickles and pickled products 500 ppm
*Vitamin preparations, the maximum intake of polysorbate 80 per day 175-475 milligrams
*Shortenings and edible oils 1% (with polysorbate 60 or not) cottage cheese 0.008%
*Whipped edible oil topping 0.4% with/not sorbitan monostearate/polysorbate 60/polysorbate 65
*Gelatin desserts and mixes 0.082%
*Barbecue sauce 0.005%
EFSA
Polysorbate 80 is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized in “Additives other than colours and sweeteners”.
Approved uses of Polysorbate 80:
Polysorbate 80's application is listed together with other polysorbates: polysorbate 20 (E432), 40(E434), 60(E435), 65(E436), with the maximum usages 500-1000mg/kg.
Polysorbate 80's usage is “quantum satis” in power or liquid food supplements (not for infants and young children).
The following food may contain Polysorbate 80:
*Flavoured fermented milk products
*Milk and cream analogues
*Fat emulsions for baking
*Sugar confectionery
*Chewing gum
*Decorations, coatings and fillings
*Fine bakery wares
*Soups, sauces
*Desserts
PHYSICAL and CHEMICAL PROPERTIES of POLYSORBATE 80:
Vapor Pressure： <1 mm Hg ( 20 °C)
PH： pH of 5% aqueous solution between 6 and 8
Appearance Form: liquid
Color: yellow
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: > 113 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 1,33 hPa at 20 °C
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties No data available
Oxidizing properties: No data available
Other safety information: No data available
Acid value: ≤2.0(mg KOH/g)
Saponification value: 45-55(mg KOH/g)
Hydroxyl value: 65~80(mg KOH/g)
Moisture: ≤3.0(w/%)
Residue on ignition: ≤0.25(w/%)
Oxyethylen: 65~69.5(w/%)
Color: Yellow to Amber
Content And Storage: Indoors +20°C
Density: 1.0800 g/mL
Molecular Formula: (C2H4O)x(C2H4O)z(C2H4O)y(C2H4O)wC24H44O6
MDL Number: MFCD00082107
InChI Key: HDTIFOGXOGLRCB-KTKRTIGZNA-N
SMILES: CCCCCCCCC=C/CCCCCCCC(=O)OCCOCC(OCCO)C1OCC(OCCO)C1OCCO
IUPAC Name: 2-{2-[3,5-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy}ethyl (9E)-octadec-9-enoate
Molecular Weight (g/mol): 604.82
Solubility: Solubility in water: 100g/L.
Other solubilities: 100g/L isopropyl alcohol, 10g/L xylene,
insoluble in propylene glycol and mineral oil
Form: Viscous Liquid
Molecular Weight: 604.8
Molecular Formula: C32H60O10
Melting Point: -21°C
Flash Point: >110°C
Purity: 99%+
Density: 1.064
Appearance: Clear Colourless Oil
Storage: Room Temperature
Assay: 0.99
Refractive Index: 1.471-1.473
Stability: Stable under normal temperatures and pressures.
Viscosity: 300–500 centistokes (@25°C)
Formula: C64H124O26
Molar Mass: 1310 g/mol
Appearance: Powder
Monoglyceride Content: Minimum 40%
Water Content: Maximum 1.0%
Acid Value (mg KOH/g): Maximum 10.0
Saponification Value (mg/g): Range of 130-160
Molar mass: 1310 g/mol
Appearance: Amber colored liquid, Amber viscous grease
Density: 1.102 g/mL, oily liquid
Boiling point: > 100°C
Solubility in water: 100 mL/L
Solubility in other solvents:
soluble in ethanol
cottonseed oi, corn oil
ethyl acetate, methanol, toluene
Viscosity: 300–500 centistokes (@25°C)
Hydroxyl value: 65~82
Saponification number: 43~55
Acid value: ≤2
PSA： 133.14000
XLogP3： 4.46260
Appearance：: Polysorbate 80 is an amber-colored viscous liquid.
pH: (5% aqueous solution) 5-7.
Faint odor and bitter taste. (NTP, 1992)
Density： 1.06-1.10 g/cm3
Melting Point： -21ºC
Boiling Point： > 100ºC
Flash Point： >110ºC
Refractive Index： 1.471-1.473
Water Solubility： H2O: 5-10 g/100 mL at 23 ºC
Storage Conditions： Store at RT.
Chemical Formula: C64H124O26
Molar Mass: 1310 g/mol
Appearance: Amber-colored oil
Density: 1.102 g/mL
Boiling Point: > 100°C
Solubility in Water: 100 mL/L
Solubility in Other Solvents: It is soluble in ethanol,
cottonseed oil, corn oil, ethyl acetate, methanol, and toluene.
Appearance: pale yellow to orange oily liquid (est)
Assay: 96.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.06400 @ 25.00 °C.
Refractive Index: 1.47200 @ 20.00 °C.
Boiling Point: 695.00 to 696.00 °C. @ 760.00 mm Hg (est)
Acid Value: 80.00 max. KOH/g
Flash Point: 235.00 °F. TCC (112.78 °C.)
logP (o/w): 4.392 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in: alcohol, oils, water, ethyl acetate, methanol, toluene, water, 0.01999 mg/L @ 25 °C (est)
Insoluble in: mineral oil, petroleum ether
pH: 11.0
Solubility: Soluble in water
Viscosity: High
INCI: Coco-Glucoside
CAS Number: 141464-42-8
Potential Applications: Shampoo, hand wash, body wash, face wash, bubble bath, solid bars
Usage: Up to 25%
Solubility: Water Soluble
Palm Free: Yes
Vegan: Yes
IUPAC Name: D-Glucopyranose, oligomeric, C10-16-alkyl glycosides
INCI Name: Coco Glucoside
CAS Numbers: 110615-47-9, 68515-73-1
Molar Mass: Not specified (a mixture)
Density: 1.15 g/mL at 20°C
Solubility: Miscible with water and most polar solvents
Texture: Slippery, detergenty
Scent: Characteristically detergenty
Active Surfactant Matter: 55%
pH: 11.5–12.5
Charge: Non-ionic
Solubility: Water
Molecular Weight: 604.81300
Exact Mass: 604.41900
EC Number: 500-019-9
DSSTox ID: DTXSID0021175
Color/Form: Yellow to orange colored, oily liquid
Lemon- to amber-colored, oily liquid
HScode: 2932999099
PSA: 133.14000
XLogP3: 4.46260
Appearance: Polysorbate 80 is an amber-colored viscous liquid.
pH (5% aqueous solution) 5-7.
Faint odor and bitter taste.
Density: 1.06-1.10 g/cm3
Melting Point: -21ºC
Boiling Point: > 100ºC
Flash Point: >110ºC
Refractive Index: 1.471-1.473
Water Solubility: H2O: 5-10 g/100 mL at 23 ºC
Storage Conditions: Store at RT.
Vapor Pressure: <1 mm Hg (20 °C)
PH: pH of 5% aqueous solution between 6 and 8
Experimental Properties: Hydroxyl radical reaction rate constant = 3.35X10-10 cu cm/molec-sec at 25 °C (est)
Air and Water Reactions: Water soluble.
Reactive Group: Ethers
Reactivity Profile: POLYSORBATE 80 is incompatible with strong alkalis and oxidizers.
FIRST AID MEASURES of POLYSORBATE 80:
-Description of first-aid measures
*If inhaled
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of POLYSORBATE 80:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
FIRE FIGHTING MEASURES of POLYSORBATE 80:
-Extinguishing media:
--Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
--Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYSORBATE 80:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection
Use safety glasses.
*Skin protection
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 30 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of POLYSORBATE 80:
-Conditions for safe storage, including any incompatibilities:
Storage conditions
Tightly closed.
Store at room temperature.
STABILITY and REACTIVITY of POLYSORBATE 80:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available
