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RADIAMULS SORB 2157K is a high HLB emulsifier used in a wide variety of food applications, from bread to ice cream formulations.
RADIAMULS SORB 2157K, commonly known as polysorbate 80, is a synthetic compound that is widely applied in a variety of fields, including foods, medicines, and cosmetics.
In food production, RADIAMULS SORB 2157K is commonly used as a defoamer for the fermenting process of some wines and as a emulsifier in ice-cream or “puddings” to keep the creamy texture without separating.
CAS: 9005-65-6
MF: C24H44O6
MW: 428.600006103516
EINECS: 500-019-9
Synonyms
CHROMOGENIC SELECTIVE E.COLI 55MM;TRYPTONE SOY BROTH 120X15ML;TRYPTONE SOY BROTH 20X15ML;TWEEN(R) 80 Vetec(TM) reagent grade;CCA COLIFORMS CHROMOGENIC A. (ISO) 55MM;armotanpmo-20;atlox1087;atlox8916tf
RADIAMULS SORB 2157K is also extensively applied in pharmaceutical industry, where it can be found in some vaccines, vitamins and supplements.
RADIAMULS SORB 2157K is an effective excipient to stabilize aqueous formulations of medications for parenteral administration and to improve the consistency of gel capsules, thus to make pills disperse in the stomach.
Besides, RADIAMULS SORB 2157K commonly serve as a surfactant and solubilizer in the production of soaps and cosmetics, which is effective to help dissolve ingredients and make products look creamier and more attractive.
In laboratory, RADIAMULS SORB 2157K is occasionally used for a test to identify the phenotype of a strain or isolate, such as mycobacteria.
A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by an oleoyl group.
RADIAMULS SORB 2157K Chemical Properties
Melting point: -25 °C
Boiling point: >100°C
Density: 1.08 g/mL at 20 °C
Vapor pressure: <1 mm Hg ( 20 °C)
Refractive index: n20/D 1.473
FEMA: 2917 | POLYSORBATE 80
Fp: >230 °F
Storage temp.: -20°C
Solubility: DMSO (Soluble), Methanol (Slightly)
Form: viscous liquid
Color: Amber
Specific Gravity: 1.080 (25/4℃)
PH Range: 6
Odor: mild alcoholic
PH: 5-7 (50g/l, H2O, 20℃)
Odor Type: alcoholic
Biological source: synthetic
Water Solubility: 5-10 g/100 mL at 23 ºC
Merck: 14,7582
Hydrophilic-Lipophilic Balance (HLB) 10
LogP 4.392 (est)
EPA Substance Registry System Polysorbate 80 (9005-65-6)
RADIAMULS SORB 2157K is a polyethylene sorbitol ester, with a calculated molecular weight of 1,310 daltons, assuming 20 ethylene oxide units, sorbitol, and 1 oleic acid as the primary fatty acid.
RADIAMULS SORB 2157K are a series of nonionic surfactants derived from sorbitan esters.
They are soluble or dispersible in water but differ widely in organic and oil solubilities.
RADIAMULS SORB 2157K has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture,5 growing of tubercule bacilli,6 and emulsifying and dispersing substances in medicinal and food products.
RADIAMULS SORB 2157K has little or no activity as an anti-bacterial agent1 except it has been shown to have an adverse effect on the antibacterial effect of methyl paraben and related compounds.
Polysorbates have been reported to be incompatible with alkalis, heavy metal salts, phenols, and tannic acid.
They may reduce the activity of many preservatives.
RADIAMULS SORB 2157K has a faint, characteristic odor and a warm, somewhat bitter taste.
RADIAMULS SORB 2157K is a mixture of oleate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides.
Characteristics
RADIAMULS SORB 2157K, commercially known as Polysorbate-80, is a viscous, water-soluble Yellow to amber liquid derived from polyethoxylated sorbitan and oleic acid.
RADIAMULS SORB 2157K is structurally similar to the (polyethylene) glycols and used both in injections (0.8-8.0%) and in oral suspension (0.375% w/v).
A number of anticancer drugs can be formulated by Tween 80.
Typical examples include etoposide and minor groove-binding cyclopropylpyrroloindole analogues like carzelesin.
Uses
RADIAMULS SORB 2157K is a general purpose mid-range HLB, ethoxylated, nonionic surfactant suggested for use in textile chemicals (emulsifier, lubricant), household products and cosmetic formulations (o/w emulsifier, viscosity modifier).
RADIAMULS SORB 2157K is used as an antistat for PVC and as an antifog for PP, PE, PVC, PS.
RADIAMULS SORB 2157K is used as an emulsifier (ice cream, whipped topping) and as a solubilizing and dispersing agent in pickles and special vitamin-mineral preparations.
RADIAMULS SORB 2157K is the trade name of a detergent that can be useful in identifying mycobacteria that possess a lipase that splits the compound into oleic acid and polyoxyethylated sorbitol.
RADIAMULS SORB 2157K is used as an additive for cell culture media.
