Sodium benzenecarboxylate works by disrupting the metabolic processes of microorganisms, thus preventing their growth and spoilage of food products.
Sodium benzenecarboxylate is particularly effective in acidic conditions, which makes it suitable for use in acidic foods and beverages such as soft drinks, fruit juices, pickles, and condiments.
Sodium benzenecarboxylate is considered safe for consumption when used within the approved limits set by regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).
CAS Number: 532-32-1
EC Number: 208-534-8
Molecular Formula: C7H5NaO2
Molecular Weight: 144.10317
Synonyms: Sodium benzenecarboxylate, 532-32-1, Sobenate, Antimol, Benzoic acid, sodium salt, Benzoic acid sodium salt, Benzoate sodium, Benzoate of soda, Benzoate, sodium, sodium;benzoate, Sodiumbenzoate, Natrium benzoicum, FEMA No. 3025, Fuminaru, Benzoan sodny, Caswell No. 746, Microcare sb, PUROX S, FEMA Number 3025, Benzoan sodny [Czech], CCRIS 3921, HSDB 696, Benzoesaeure (na-salz), UNII-OJ245FE5EU, EINECS 208-534-8, OJ245FE5EU, benzoic acid sodium, EPA Pesticide Chemical Code 009103, INS NO.211, DTXSID1020140, E211, AI3-07835, Benzoesaeure (na-salz) [German], INS-211, DTXCID90140, Sodium benzenecarboxylate [USAN:JAN], E-211, CHEBI:113455, Sodium benzenecarboxylate [USAN:JAN:NF], EC 208-534-8, AMMONUL COMPONENT Sodium benzenecarboxylate, UCEPHAN COMPONENT Sodium benzenecarboxylate, Sodium benzenecarboxylate COMPONENT OF AMMONUL, Sodium benzenecarboxylate COMPONENT OF UCEPHAN, Sodium benzoic acid, Sodium benzenecarboxylate (II), Sodium benzenecarboxylate [II], Sodium benzenecarboxylate (MART.), Sodium benzenecarboxylate [MART.], Sodium benzenecarboxylate (EP MONOGRAPH), Sodium benzenecarboxylate [EP MONOGRAPH], C7H5NaO2, MFCD00012463, BzONa, monoSodium benzenecarboxylate, Sodium benzenecarboxylate USP, Sodium benzenecarboxylate,(S), Sodium benzenecarboxylate (TN), SCHEMBL823, CHEMBL1356, Sodium benzenecarboxylate [MI], Sodium benzenecarboxylate (JP17/NF), Sodium benzenecarboxylate [FCC], Sodium benzenecarboxylate [JAN], C7-H6-O2.Na, Sodium benzenecarboxylate [FHFI], Sodium benzenecarboxylate [HSDB], Sodium benzenecarboxylate [INCI], Sodium benzenecarboxylate [USAN], Sodium benzenecarboxylate [VANDF], Sodium benzenecarboxylate [USP-RS], Sodium benzenecarboxylate [WHO-DD], Sodium benzenecarboxylate (Fragrance Grade), Benzoic acid, sodium salt (1:1), HY-Y1316, Tox21_300125, Sodium benzenecarboxylate [ORANGE BOOK], AKOS003053000, AKOS015890021, CCG-266169, LS-2390, NCGC00254072-01, CAS-532-32-1, CS-0017788, E 211, FT-0645126, S0593, D02277, A829462, Q423971, J-519752.
Sodium benzenecarboxylate determination in fruit juices, sodas, soy sauce, ketchup, peanut butter, cream cheese and other foods by HPLC method has been proposed.
Sodium benzenecarboxylate is a Food and Drug Administration-approved nontoxic drug.
Sodium benzenecarboxylate is used as a preservative in both cosmetics and food products, where it prevents both bacterial and fungal growth, though it is more active against the latter.
Sodium benzenecarboxylate is also used as a preservative in food and drink.
Sodium benzenecarboxylate is a popular ingredient in cosmetics, not because of some amazing skin care property but because it works as a preservative.
Sodium benzenecarboxylate an active ingredient in a skin care product like a nutrient or vitamin is used to nourish your skin cells, chances are the same nutrients also make good food for microbes in the air which can colonise your product and turn it mouldy.
By including Sodium benzenecarboxylate alongside the active ingredient, you can extend the life span of the product and fight off the growth of mould.
Sodium benzenecarboxylate can be obtained via acid-base reaction between benzoic acid and sodium bicarbonate/sodium hydroxide solution.
Sodium benzenecarboxylate is the salt of benzoic acid, an acid that is found naturally in foods like cranberries, apricots, mushrooms, and honey.
The U.S. Food and Drug Administration (FDA) has designated it a “generally recognised as safe” ingredient.
Sodium benzenecarboxylate is a food additive used as preservative in acidic food and drinks – mostly those with a pH of less than 5.
Added as an anti-fungal, Sodium benzenecarboxylate is used to balance the pH inside individual cells, raising the overall acidity of the product and creating an environment in which it is more difficult for fungi to grow.
These fungi can invade food and cause Sodium benzenecarboxylate to spoil, dramatically reducing its shelf life.
Sodium benzenecarboxylate is a common food preservative and additive that is widely used in the food and beverage industry.
Sodium benzenecarboxylate is the sodium salt of benzoic acid and has the chemical formula C7H5NaO2.
Sodium benzenecarboxylate is a white, odorless, and crystalline powder that is highly soluble in water.
One of the primary reasons for using Sodium benzenecarboxylate as a preservative is its ability to inhibit the growth of bacteria, yeast, and fungi.
Sodium benzenecarboxylate is particularly effective in acidic conditions, which makes it suitable for use in acidic foods and beverages such as soft drinks, fruit juices, pickles, and condiments.
Sodium benzenecarboxylate works by disrupting the metabolic processes of microorganisms, thus preventing their growth and spoilage of food products.
Sodium benzenecarboxylate is important to note that Sodium benzenecarboxylate is considered safe for consumption when used within the approved limits set by regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).
Some individuals may be sensitive or allergic to Sodium benzenecarboxylate, and in rare cases, Sodium benzenecarboxylate can cause adverse reactions or exacerbate certain health conditions.
Sodium benzenecarboxylate is always recommended to read food labels and consult with healthcare professionals if you have any concerns.
Sodium benzenecarboxylate is the sodium salt form of benzoic acid, and is synthesized by reacting benzoic acid with sodium hydroxide.
While Sodium benzenecarboxylate must be manufactured, benzoic acid is found naturally in certain foods such as apples, prunes, plums, greengages, cloves and certain berries.
The independent Cosmetic Ingredient Review panel has ruled Sodium benzenecarboxylate safe as used in cosmetics, where maximum usage levels range from 0.5–1%.
In its raw form, Sodium benzenecarboxylate is a white, crystalline solid that dissolves in water.
Sodium benzenecarboxylate is the sodium salt of benzoic acid, widely used as a food preservative (with an E number of E211) and a pickling agent.
Sodium benzenecarboxylate appears as a white crystalline chemical with the formula C6H5COONa.
Glyceryl monostearate is not considered highly flammable.
Sodium benzenecarboxylate has a relatively high flash point and is not expected to contribute significantly to fire hazards.
However, like any organic compound, Sodium benzenecarboxylate can burn under certain conditions.
Sodium benzenecarboxylate is important to handle and store glyceryl monostearate away from open flames and ignition sources.
Sodium benzenecarboxylate is generally stable under normal conditions.
Sodium benzenecarboxylate can undergo decomposition at high temperatures, which may release potentially hazardous by-products.
Sodium benzenecarboxylate is important to avoid excessive heat or prolonged exposure to high temperatures.
While Sodium benzenecarboxylate is considered safe for consumption and use in regulated concentrations, individuals with specific health conditions or allergies may experience adverse effects.
If have a known sensitivity or allergy to glyceryl monostearate or related substances, Sodium benzenecarboxylate is advisable to avoid products containing it and consult with a healthcare professional.
Sodium benzenecarboxylate is subject to regulations and restrictions set by different regulatory bodies depending on the country or region.
These regulations typically define the permitted concentrations, uses, and labeling requirements.
Sodium benzenecarboxylate is important for manufacturers and formulators to comply with these regulations to ensure the safe use of Sodium benzenecarboxylate in consumer products.
Sodium benzenecarboxylate is a sodium salt of benzoic acid, that is freely soluble in water compared to benzoic acid.
Sodium benzenecarboxylate is generally used as an antimicrobial preservative in cosmetics, food, and pharmaceuticals.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Sodium benzenecarboxylate, also known as benzoic acid sodium, is commonly used as food preservatives in food industry, odorless or with slight smell of benzoin, and tastes sweet astringency.
Stable in air, can absorb moisture in open air.
Sodium benzenecarboxylate’s naturally found in blueberry, apple, plum, cranberry, prunes, cinnamon and cloves, with weaker antiseptic performance than benzoic acid.
Antiseptic performance of 1.180g Sodium benzenecarboxylate is equivalent of about 1g benzoic acid.
In acidic environment, Sodium benzenecarboxylate have obvious inhibitory effect on a variety of microorganisms: when pH is at 3.5, 0.05% solution can completely inhibit the growth of yeast; while when pH is above 5.5, Sodium benzenecarboxylate has poor effect on a lot of mold and yeast; hardly has any effect in alkaline solution.
After Sodium benzenecarboxylate enters into the body, in the process of biotransformation, it would combine with glycine to be uric acid, or combine with glucuronic acid to be glucosiduronic acid, and all to be eliminated from the body in urine, not to accumulate in the body.
As long as Sodium benzenecarboxylate is within the scope of the normal dosage, Sodium benzenecarboxylate would be harmless to the human body, and it is a safe preservatives.
Sodium benzenecarboxylate also can be used for carbonated beverages, concentrated juice, margarine, chewing gum base, jam, jelly, soy sauce, etc. Human acceptable daily intake (ADI) < 5 mg/kg body weight (take benzoic acid as calculation basis).
Sodium benzenecarboxylate has big lipophilicity, and it is easy to penetrate cell membrane into the cells, interfere in permeability of cell membrane, and inhibit cell membrane’s absorption of amino acids; cause Ionization acidification of alkaline storage in the cell when entering into, inhibit activity of respiratory enzymes, and stop condensation reaction of acetyl coenzyme A, and thereby achieve the purpose of food antiseptic.
Sodium benzenecarboxylate is commonly produced by the neutralization of sodium hydroxide (NaOH) with benzoic acid (C6H5COOH), which is itself produced commercially by partial oxidation of toluene with oxygen.
Sodium benzenecarboxylate is a widely used food preservative, with an E number of E211.
Sodium benzenecarboxylate is the sodium salt of benzoic acid and exists in this form when dissolved in water.
Sodium benzenecarboxylate can be produced by reacting sodium hydroxide with benzoic acid.
Sodium benzenecarboxylate is a salt made of sodium and benzoic acid.
Sodium benzenecarboxylate can be found naturally in fruit and spices like apples, cranberries and cinnamon.
Despite being naturally occurring, Sodium benzenecarboxylate is usually synthesised in a lab when needed in large quantities for cosmetics.
Sodium benzenecarboxylate is a synthetic chemical produced when benzoic acid, which is found naturally in some fruits and spices, is combined with sodium hydroxide.
Sodium benzenecarboxylate is a preservative that can be found in acidic foods such as salad dressings, carbonated drinks, jams, juices, and condiments.
Sodium benzenecarboxylate is also found in mouthwashes, silver polishes, cough syrups, soaps, and shampoos.
Sodium benzenecarboxylate does not occur naturally, but benzoic acid is found in many plants, including cinnamon, cloves, tomatoes, berries, plums, apples, and cranberries (2Trusted Source).
Sodium benzenecarboxylate is synthesised or artificially prepared from the substances benzoic acid and sodium hydroxide.
Additionally, certain bacteria produce benzoic acid when fermenting dairy products like yogurt (1, 3Trusted Source).
Sodium benzenecarboxylate is used as an antifungal preservative in cosmetics and in food under the name E211.
Sodium benzenecarboxylate is therefore very effective against fungi, yeasts and bacteria.
Sodium benzenecarboxylate is made quite easily with soda, water and benzoic acid.
Sodium benzenecarboxylate is found naturally in some fruits such as plums, prunes or apples.
Sodium benzenecarboxylate is an organic alcohol found in many fruits and teas.
Sodium benzenecarboxylate has a hydroxyl group (-OH), while the related compound, Benzoic Acid has a carboxyl group (-COOH).
Sodium benzenecarboxylate, Calcium Benzoate and Potassium Benzoate are salts of Benzoic Acid.
Sodium benzenecarboxylate is an ester of Benzyl Alcohol and Benzoic Acid.
Sodium benzenecarboxylate, also known as Benzoic acid sodium salt , can be made by chemically by reacting sodium hydroxide with Benzoic acid.
Sodium benzenecarboxylate is odorless or with a slight smell of Benzoin, and tastes sweet astringency.
Stable in air Sodium benzenecarboxylate can absorb moisture in open air as a preservative Sodium benzenecarboxylate is bacteriostatic and fungistatic under acidic conditions.
Sodium benzenecarboxylate as a food additive, Sodium benzenecarboxylate has the E number E211.
Since Sodium benzenecarboxylate contains a natural ingredient, Sodium benzenecarboxylate is probably safe, right? After all, the US Food and Drug Administration (FDA) and the Canadian Health Protection Branch have pronounced this chemical preservative to be acceptable when consumed in low amounts.
Sodium benzenecarboxylate is a preservative added to some sodas, packaged foods, and personal care products to prolong shelf life.
Sodium benzenecarboxylate is best known as a preservative used in processed foods and beverages to extend shelf life, though it has several other uses.
Sodium benzenecarboxylate is a common food preservative and a mold inhibitor.
Sodium benzenecarboxylate is most effective in low acid foods and beverages and baked goods such as breads, cakes, pies, tortillas and many others.
Sodium benzenecarboxylate’s an odorless, crystalline powder made by combining benzoic acid and sodium hydroxide.
Sodium benzenecarboxylate is a good preservative on its own, and combining it with sodium hydroxide helps it dissolve in products.
When Sodium benzenecarboxylate is combined with ascorbic acid (vitamin C) in acidic conditions, such as in certain beverages, it can form Sodium benzenecarboxylate.
Sodium benzenecarboxylate is a known carcinogen and may pose health risks if consumed in excessive amounts.
There have been claims that Sodium benzenecarboxylate, along with certain food colorings, may contribute to hyperactivity or attention deficit hyperactivity disorder (ADHD) symptoms in some susceptible individuals, particularly in children.
Sodium benzenecarboxylate, the scientific evidence regarding this link is limited and inconclusive.
While the risk is low when used within regulatory limits, under certain conditions (such as exposure to heat, light, or acidic conditions), Sodium benzenecarboxylate can react with other ingredients to form benzene.
Sodium benzenecarboxylate is a potent carcinogen and should be minimized in food and beverage products.
Regulatory authorities monitor and set limits on the amount of benzene allowed in consumer products.
Uses of Sodium benzenecarboxylate:
Sodium benzenecarboxylate is most widely used in acidic foods such as salad dressings (for example acetic acid in vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (acetic acid), condiments, and frozen yogurt toppings.
Sodium benzenecarboxylate helps maintain the freshness and quality of these beverages by preventing microbial spoilage.
Sodium benzenecarboxylate can be found in certain dairy products like yogurt, cheese, and ice cream.
Sodium benzenecarboxylate helps prevent the growth of spoilage-causing microorganisms and extends the shelf life of these perishable products.
Many condiments and sauces, including ketchup, mayonnaise, mustard, and soy sauce, may contain Sodium benzenecarboxylate as a preservative.
Sodium benzenecarboxylate helps prevent bacterial growth and maintains the flavor and quality of these products.
Sodium benzenecarboxylate is sometimes used as a preservative in pet food and animal feed to ensure its safety and extend its shelf life.
Sodium benzenecarboxylate helps protect against the growth of bacteria and molds that can lead to spoilage and contamination.
In water treatment applications, Sodium benzenecarboxylate can be used as a corrosion inhibitor and to control microbial growth in cooling towers and industrial water systems.
Sodium benzenecarboxylate helps prevent the formation of scale and biofilm, which can negatively impact system efficiency.
Sodium benzenecarboxylate has been studied for its potential use as a plant growth regulator and for disease control in agriculture and horticulture.
Sodium benzenecarboxylate may have fungicidal properties and can be used to inhibit the growth of certain plant pathogens.
Sodium benzenecarboxylate is sometimes used in fireworks compositions to produce green-colored flames when ignited.
Sodium benzenecarboxylate acts as a colorant and helps generate the desired visual effects.
Sodium benzenecarboxylate is used in a variety of personal care products, including hair care products (shampoos, conditioners, styling products), skin care products (lotions, creams, cleansers), and oral care products (toothpaste, mouthwash).
Sodium benzenecarboxylate serves as a preservative to maintain the product's stability and prevent the growth of bacteria and fungi.
Sodium benzenecarboxylate can be found in certain cleaning products, such as liquid soaps, detergents, and disinfectants.
Sodium benzenecarboxylate helps inhibit the growth of microorganisms and extends the shelf life of these products.
Sodium benzenecarboxylate is utilized as a preservative in adhesives and sealants.
Sodium benzenecarboxylate helps prevent microbial growth, ensuring the integrity and stability of the product.
In the oil and gas sector, Sodium benzenecarboxylate is sometimes used as a corrosion inhibitor in drilling fluids, production fluids, and pipeline systems.
Sodium benzenecarboxylate helps protect metal surfaces from corrosion caused by water, acids, and bacteria.
Sodium benzenecarboxylate has been used in the photographic industry as a developing agent in certain photographic processes.
with the advent of digital photography, its use in this industry has significantly declined.
Sodium benzenecarboxylate can be used as a dye auxiliary in textile printing and dyeing processes.
Sodium benzenecarboxylate is also used as a preservative in medicines and cosmetics.
Sodium benzenecarboxylate Under these conditions it is converted into benzoic acid (E210), which is bacteriostatic and fungistatic.
Sodium benzenecarboxylate is generally not used directly due to its poor water solubility.
Concentration as a food preservative is limited by the FDA in the U.S. to 0.1% by weight.
Sodium benzenecarboxylate is also allowed as an animal food additive at up to 0.1%, per the Association of American Feed Control Officials.
Sodium benzenecarboxylate has been replaced by potassium sorbate in the majority of soft drinks in the United Kingdom.
Sodium benzenecarboxylate is a preservative used in skincare products to prevent the overgrowth of microorganisms, Sodium benzenecarboxylate is a mold inhibitor that helps to reduce the growth of mold and bacteria.
Sodium benzenecarboxylate is widely used as a preservative in food, medicine, cosmetics and animal feeds.
Sodium benzenecarboxylate is used in the treatment of hyperammonemia and urea cycle disorders.
Sodium benzenecarboxylate is used in the fireworks as a fuel in whistle mix.
Sodium benzenecarboxylate is also used in the preparation of toothpaste and mouthwashes.
Sodium benzenecarboxylate finds application in most of the acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments.
Sodium benzenecarboxylate is produced by the neutralization of benzoic acid with sodium hydroxide.
Sodium benzenecarboxylate also has applications beyond the food industry.
Sodium benzenecarboxylate is used in various personal care products, such as cosmetics, shampoos, and lotions, to inhibit the growth of bacteria and fungi.
Sodium benzenecarboxylate is employed as a corrosion inhibitor in automotive antifreeze and as a medication in certain pharmaceutical formulations.
Sodium benzenecarboxylate is a also the preservative found in many foods and soft drinks.
Many soft drinks contain Sodium benzenecarboxylate as both a preservative, and to enhance the flavour effect of their high-fructose corn syrup.
Sodium benzenecarboxylate is most commonly added to acidic foods like cider vinegars, pickles, condiments, jams and conserves, and soy sauce to control mold, bacteria, yeasts, and other microbes.
Sodium benzenecarboxylate interferes with their ability to make energy.
Sodium benzenecarboxylate only converts to benzoic acid in acidic environments, Sodium benzenecarboxylate is not used for its anti-microbial action unless the pH is below about 3.6.
Sodium benzenecarboxylate is commonly used as a preservative in non-alcoholic beverages such as soft drinks, energy drinks, sports drinks, and flavored water.
Sodium benzenecarboxylate is primarily used as a preservative in various food and beverage products.
Sodium benzenecarboxylate helps to prevent the growth of microorganisms, extending the shelf life of these products.
Sodium benzenecarboxylate is commonly found in carbonated drinks, fruit juices, jams, jellies, salad dressings, condiments, and processed foods.
Sodium benzenecarboxylate is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited.
Sodium benzenecarboxylate is also an important preservative of acid type food.
Sodium benzenecarboxylate transforms into effective form of benzoic acid during application.
Sodium benzenecarboxylate agent is a very important preservative of acid type fodder.
Sodium benzenecarboxylate transforms into effective form of benzoic acid during application.
Sodium benzenecarboxylate for application range and dosage.
In addition, Sodium benzenecarboxylate also can be used as food preservative.
Sodium benzenecarboxylate used in the research of pharmaceutical industry and plant genetic, also used as dye intermediates, fungicide and preservatives.
Sodium benzenecarboxylate is used as food additive (preservative), fungicide in pharmaceutical industry, dye mordant, plasticizer in plastic industrial, and also used as organic synthetic intermediate of spices and others.
Sodium benzenecarboxylate is a preservative.
Sodium benzenecarboxylate is bacteriostatic and fungistatic under acidic conditions.
Sodium benzenecarboxylate is most widely used in acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments.
Sodium benzenecarboxylate is also used as a preservative in medicines and cosmetics.
As a food additive, Sodium benzenecarboxylate has the E number E211.
Sodium benzenecarboxylate is much better than benzoic acid at dissolving in water.
Sodium benzenecarboxylate is one of its most characteristic physical properties.
Although the excipient Sodium benzenecarboxylate conserves slightly better than Sodium benzenecarboxylate, you can compensaté for this by either using a little more or lowering the pH by adding an acid to your product.
Sodium benzenecarboxylate is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited.
Sodium benzenecarboxylate is also one of the fastest burning rocket fuels and provides a lot of thrust and smoke.
Sodium benzenecarboxylate does have its downsides: there is a high danger of explosion when the fuel is sharply compressed because of the fuel's sensitivity to impact.
Sodium benzenecarboxylate can act as a food preservative.
Production methods of Sodium benzenecarboxylate:
Neutralized by benzoic acid and sodium bicarbonate.
Put water and sodium bicarbonate into the neutralizing pot, boil Sodium benzenecarboxylate and make it dissolved into sodium bicarbonate solution.
Mix Sodium benzenecarboxylate with benzoic acid until PH value of the reaction solution reaches to 7-7.5.
Heat Sodium benzenecarboxylate to emit over carbon dioxide, and then add active carbon to decolorize it for half an hour.
Do suction filtration, after filtrate gets concentrated, put Sodium benzenecarboxylate into flaker tray, dry it to be sheets in the drum, crush it, and then Sodium benzenecarboxylate is made.
Consumption rate of benzoic acid (99.5%) 1045kg/t and sodium bicarbonate (98%) 610kg/t.
Use 32% soda solution to neutralize benzoic acid in the pot to reach PH value of 7.5, and neutralization temperature is 70℃.
Use 0.3% active carbon to decolorize the neutralized solution, vacuum filter it, concentrate, dry it and then it comes to powdered Sodium benzenecarboxylate.
C6H5COOH+Na2CO3→C6H5COONa
To get it by toluene oxidation made benzoic acid reacting with sodium bicarbonate, sodium carbonate or sodium hydroxide.
Sodium benzenecarboxylate is prepared by adding benzoic acid to a hot concentrated solution of sodium carbonate until effervescence ceases.
The solution is then evaporated, cooled and allowed to crystallize or evaporate to dryness, and then granulated.
Safety Profile of Sodium benzenecarboxylate:
Sodium benzenecarboxylate is generally recognized as safe (GRAS) by regulatory authorities when used in accordance with approved limits.
The FDA and other regulatory agencies have set specific maximum levels for its use in food products.
However, Sodium benzenecarboxylate is worth noting that excessive consumption of foods and drinks containing Sodium benzenecarboxylate, especially in combination with certain other substances, may have potential health effects.
For instance, when Sodium benzenecarboxylate is combined with ascorbic acid (vitamin C) or citric acid, Sodium benzenecarboxylate can form benzene, a known carcinogen.
To minimize the formation of benzene, manufacturers are required to limit the levels of these substances in products containing Sodium benzenecarboxylate.
Ingested Sodium benzenecarboxylate is conjugated with glycine in the liver to yield hippuric acid, which is excreted in the urine.
Symptoms of systemic benzoate toxicity resemble those of salicylates.
Whereas oral administration of the free-acid form may cause severe gastric irritation, benzoate salts are well tolerated in large quantities: e.g. 6 g of Sodium benzenecarboxylate in 200mL of water is administered orally as a liver function test.
Clinical data have indicated that Sodium benzenecarboxylate can produce nonimmunological contact urtcaria and nonimmunological immediate contact reactions.
However, Sodium benzenecarboxylate is also recognized that these reactions are strictly cutaneous, and Sodium benzenecarboxylate can therefore be used safely at concentrations up to 5%.
However, this nonimmunological phenomenon should be considered when designing formulations for infants and children.
Other adverse effects include anaphylaxis and urticarial reactions, although a controlled study has shown that the incidence of urticaria in patients given benzoic acid is no greater than that with a lactose placebo.
Sodium benzenecarboxylate has been recommended that caffeine and Sodium benzenecarboxylate injection should not be used in neonates; however, Sodium benzenecarboxylate has been used by others in the treatment of some neonatal metabolic disorders.
Sodium benzenecarboxylate has been suggested that there is a general adverse effect of benzoate preservatives on the behavior of 3-yearold children, which is detectable by parents, but not by a simple clinical assessment.
In combination with ascorbic acid (vitamin C, E300), Sodium benzenecarboxylate and potassium benzoate form benzene, a known carcinogen.
However, in most beverages that contain both, the benzene levels are below those considered dangerous for consumption.
Heat, light and shelf life can affect the rate at which benzene is formed.
In the United States, Sodium benzenecarboxylate is designated as generally recognized as safe (GRAS) by the Food and Drug Administration.
The International Programme on Chemical Safety found no adverse effects in humans at doses of 647–825 mg/kg of body weight per day.
Cats have a significantly lower tolerance against Sodium benzenecarboxylate and its salts than rats and mice.
The human body rapidly clears Sodium benzenecarboxylate by combining it with glycine to form hippuric acid which is then excreted.
The metabolic pathway for this begins with the conversion of benzoate by butyrate-CoA ligase into an intermediate product, benzoyl-CoA, which is then metabolized by glycine N-acyltransferase into hippuric acid.
Some individuals may be sensitive or allergic to Sodium benzenecarboxylate.
Allergic reactions can manifest as symptoms like skin rashes, itching, hives, swelling, respiratory difficulties, or gastrointestinal discomfort.
Identifiers of Sodium benzenecarboxylate:
CAS Number: 532-32-1
CHEBI:113455
ChEMBL1356
ChemSpider: 10305
ECHA InfoCard: 100.007.760
E number: E211 (preservatives)
PubChem CID: 517055
RTECS number: DH6650000
UNII: OJ245FE5EU
DTXSID1020140
CAS Number: 532-32-1
Molecular Weight: 144.10
EC Number: 208-534-8
CAS number: 532-32-1
EC number: 208-534-8
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code 2916: 31 00
SCAS Number:532-32-1
Molecular Weight:144.10
Beilstein:3572467
EC Number:208-534-8
MDL number:MFCD00012463
eCl@ss:39024301
PubChem Substance ID: 329751625
NACRES: NA.21o
Properties of Sodium benzenecarboxylate:
Chemical formula: C7H5NaO2
Molar mass: 144.105 g·mol−1
Appearance: white or colorless crystalline powder
Odor: odorless
Density: 1.497 g/cm3
Melting point: 410 °C (770 °F; 683 K)
Solubility in water: 62.65 g/100 mL (0 °C)
62.84 g/100 mL (15 °C)
62.87 g/100 mL (30 °C)
74.2 g/100 mL (100 °C)[1]
Solubility: soluble in liquid ammonia, pyridine
Solubility in methanol: 8.22 g/100 g (15 °C)
7.55 g/100 g (66.2 °C)
Solubility in ethanol
2.3 g/100 g (25 °C)
8.3 g/100 g (78 °C)
Solubility in 1,4-Dioxane: 0.818 mg/kg (25 °C
Density: 1.50 g/cm3 (20 °C)
Ignition temperature >500 °C
Melting Point: 436 °C
pH value: 8 (100 g/l, H₂O, 20 °C)
Bulk density: 350 kg/m3
Solubility: 556 g/l
Computed Properties of E 211 (Sodium benzenecarboxylate)
Molecular Weight: 144.10
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 144.01872368
Monoisotopic Mass: 144.01872368
Topological Polar Surface Area: 40.1 Ų
Heavy Atom Count: 10
Complexity: 108
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Specifications of Sodium benzenecarboxylate:
Assay (acidimetric, calc. on anhydrous substance): 99.0 - 100.5 %
Assay (HPLC, calc. on anhydrous substance): 99.0 - 101.0 %
Identity: passes test
Appearance of solution (100 g/l, water) passes test
Acidity or alkalinity: passes test
Chloride (Cl): ≤ 0.02 %
Sulphate (SO₄): ≤ 0.01 %
Total chlorine: ≤ 0.03 %
Heavy metals (as Pb): ≤ 10 ppm
As (Arsenic): ≤ 1 ppm
Cd (Cadmium): ≤ 10 ppm
Cu (Copper): ≤ 10 ppm
Hg (Mercury): ≤ 1 ppm
Pb (Lead): ≤ 2 ppm
Zn (Zinc): ≤ 10 ppm
Benzene: ≤ 2 ppm
Toluene: ≤ 890 ppm
Other residual solvents (ICH Q3C): excluded by production process
Multinuclear acids: passes test
Oxidizable matter: passes test
Water (according to Karl Fischer): ≤ 1.5 %Product Information
CAS number: 532-32-1
EC number: 208-534-8
Grade: Ph Eur,BP,NF,FCC,E 211
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code: 2916 31 00