Sodium CarboxyMethyl Cellulose: a kind of cellulose derivate.
Sodium CarboxyMethyl Cellulose is one of the most essential products of cellulose ethers, which are formed by natural cellulose modification as a kind of cellulose derivate with an ether structure.
Because the acid form of Sodium CarboxyMethyl Cellulose has poor water solubility, it is usually preserved as sodium carboxymethylcellulose, widely used in many industries and regarded as monosodium glutamate in industry.
CAS: 9085-26-1
MF: C8H16NaO8
EINECS: 618-378-6
Synonyms
CARBOXYMETHYL CELLULOSE SODIUM;CARBOXYMETHYLCELLULOSE SODIUM SALT;CELLULOSE, CARBOXY METHYL, SODIUM SALT;CELLULOSE GLYCOLIC ACID SODIUM SALT;CMC 7HF;CMC 7LF;CMC 7MF;AQUACIDE I
Sodium CarboxyMethyl Cellulose is a non-toxic and biodegradable water-soluble polymer used as an adhesive and cross-linking agent in the pharmaceutical industry.
Sodium CarboxyMethyl Cellulose could be used as flocculating agent, chelating agent, emulsifier, thickening agent, water-retaining agent, sizing agent, film-forming material, and so on.
Sodium CarboxyMethyl Cellulose is also widely applied in electronics, pesticides, leather, plastics, printing, ceramics, and the daily-use chemical industry.
Moreover, due to Sodium CarboxyMethyl Cellulose's excellent properties, wide application, and developing potential fields, Sodium CarboxyMethyl Cellulose has broad application prospects.
Sodium CarboxyMethyl Cellulose is a type of cellulose that has been reacted with sodium hydroxide to form sodium carboxylate.
Sodium CarboxyMethyl Cellulose is used as an additive in processed food and pharmaceuticals, including tablets, capsules, and suspensions.
Sodium CarboxyMethyl Cellulose provides viscosity to the solution and can be used in analytical methods for measuring particle diameter.
Sodium CarboxyMethyl Cellulose has been shown to have anti-inflammatory properties and can help reduce the severity of autoimmune diseases.
Sodium CarboxyMethyl Cellulose may also have a protective effect against cancer due to its ability to bind carcinogens or reduce the production of reactive oxygen species.
Sodium CarboxyMethyl Cellulose or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Sodium CarboxyMethyl Cellulose is often used in its sodium salt form, sodium carboxymethyl cellulose.
Sodium CarboxyMethyl Cellulose used to be marketed under the name Tylose, a registered trademark of SE Tylose.
The sodium salt is used pharmaceutically as an artificial lubricant for the eye in a 0.25% solution in water under the brand name Theratears.
An injectable form has been investigated for use as a soft tissue filler.
Sodium CarboxyMethyl Cellulose is also used as a wound dressing under multiple brand names.
Sodium CarboxyMethyl Cellulose Chemical Properties
Melting point: 274 °C (dec.)
Stemp.: Room Temperature
Solubility: Aqueous Acid (Heated, Sonicated, Sparingly), Water (Heated, Sonicated, Sparingly)
Form: low viscosity
Color: Off-White to Pale Beige
Physical properties
Sodium CarboxyMethyl Cellulose is an anionic cellulose ether, with white or slightly yellow flocculent fiber powder or white powder appearance, odorless, tasteless, non-toxic; easily soluble in cold water or hot water, forming a certain viscosity clear solution.
The solution is neutral or slightly alkaline, insoluble in ethanol, ether, isopropanol, acetone and other organic solvents, soluble in 60% water-containing ethanol or acetone solution.
Sodium CarboxyMethyl Cellulose is hygroscopic, stable to light and heat, the viscosity decreases with the increase of temperature, the solution is stable at pH 2-10, pH is lower than 2, there is solid precipitation, and the viscosity decreases when pH is higher than 10.
The discoloration temperature is 227℃, the carbonization temperature is 252℃, and the surface tension of 2% aqueous solution is 71mn/n.
Sodium CarboxyMethyl Cellulose is a white or lightly yellow powder with no odor, flavor, or poisonous properties.
Sodium CarboxyMethyl Cellulose is hygroscopic and dissolves well in hot or cold water, forming a viscous solution.
Sodium CarboxyMethyl Cellulose is not soluble in organic solvents like methanol, ethanol, acetone, chloroform, and benzene.
The functional properties of Sodium CarboxyMethyl Cellulose depend on the degree of substitution of the cellulose structure (i.e., how many of the hydroxyl groups have been converted to carboxymethylene groups in the substitution reaction), as well as the chain length of the cellulose backbone structure and the degree of clustering of the carboxymethyl substituents.
Sodium CarboxyMethyl Cellulose is commonly used as a viscosity modifier or thickener and to stabilize emulsions in various products, both food and non-food-related.
Sodium CarboxyMethyl Cellulose is mainly used because it has a high viscosity, is nontoxic, and is generally considered to be hypoallergenic.
Structure
Sodium CarboxyMethyl Cellulose is a derivative of the regenerated cellulose [C6H10O5]n with hydroxy-acetic acid (hydroxyethanoic acid) CH2(OH)COOH or sodium monochloroacetate (Na[ClCH2COO]).
The Sodium CarboxyMethyl Cellulose backbone consists of D-glucose residues linked by -1,4-linkage.
Sodium CarboxyMethyl Cellulose has carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Sodium CarboxyMethyl Cellulose is often used as its sodium salt, sodium carboxymethyl cellulose.
Uses
Sodium CarboxyMethyl Cellulose is readily soluble in water and is insoluble in organic solvents.
The material is used as a soil-suspending agent in detergents, suspending agent in latex paints and as an adhesive; Sodium CarboxyMethyl Cellulose is also used as a stabilizer in food products such as ice cream.
Sodium CarboxyMethyl Cellulose is a non-toxic and odorless white flocculent powder with stable performance and is easily soluble in water.
Sodium CarboxyMethyl Cellulose's aqueous solution is a neutral or alkaline transparent viscous liquid, soluble in other water-soluble glues and resins, and insoluble.
in organic solvents such as ethanol.
Sodium CarboxyMethyl Cellulose can be used as adhesive, thickener, suspending agent, emulsifier, dispersant, stabilizer, sizing agent, etc.
Sodium CarboxyMethyl Cellulose is the product with the largest output, the most widely used and the most convenient use among cellulose ethers, commonly known as "industrial monosodium glutamate".
Sodium CarboxyMethyl Cellulose is used in applications ranging from food production to medical treatments.
Sodium CarboxyMethyl Cellulose is commonly used as a viscosity modifier or thickener and to stabilize emulsions in both food and non-food products.
Sodium CarboxyMethyl Cellulose is used primarily because it has high viscosity, is nontoxic, and is generally considered to be hypoallergenic, as the major source fiber is either softwood pulp or cotton linter.
Sodium CarboxyMethyl Cellulose is also used in non-food products which include products such as toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, reusable heat packs, various paper products, filtration materials, synthetic membranes, wound healing applications, and also in leather crafting to help burnish edges.
Sodium CarboxyMethyl Cellulose, is the carboxymethylated cellulose derivatives, also known as cellulose gum, belongs to the anionic fiberd ether, is one of the main ionic cellulose gum.
Sodium CarboxyMethyl Cellulose is an anionic polymer compound, usually derived from the reaction of natural cellulose with caustic alkali.
The molecular weight of the compound varies from several thousand to millions.
Food
Sodium CarboxyMethyl Cellulose is registered as E466 or E469 (when it is enzymatically hydrolyzed).
Sodium CarboxyMethyl Cellulose is used for a viscosity modifier or thickener and to stabilize emulsions in various products, including ice cream, mayonnaise, and beverages.
Sodium CarboxyMethyl Cellulose is also used extensively in gluten-free and reduced-fat food products.
Sodium CarboxyMethyl Cellulose's variable viscosity (high while cold, and low while hot) makes it useful in the preparation of cold foods and textures in beverages and edible gels.
With a degree of substitution (DS) around 1.0, it can prevent dehydration and shrinkage of gelatin while also contributing to a more airy structure.
In some foods, Sodium CarboxyMethyl Cellulose can be used to control oil and moisture content.
Sodium CarboxyMethyl Cellulose is used to achieve tartrate or cold stability in wine, which can prevent excess energy usage while chilling wine in warm climates.
Sodium CarboxyMethyl Cellulose is more stable than metatartaric acid and is very effective in inhibiting tartrate precipitation.
KHT crystals, in the presence of Sodium CarboxyMethyl Cellulose, grow slower and change their morphology.
Their shape becomes flatter because they lose 2 of the 7 faces, changing their dimensions.
Sodium CarboxyMethyl Cellulose molecules, negatively charged at wine pH, interact with the electropositive surface of the crystals, where potassium ions are accumulated.
The slower growth of the crystals and the modification of their shape are caused by the competition between Sodium CarboxyMethyl Cellulose molecules and bitartrate ions for binding to the KHT crystals.
Sodium CarboxyMethyl Cellulose injections have also been used in food fraud, to fraudulently increase the weight and visual appeal of shrimp and prawns so as to short-weight customers.
Sodium CarboxyMethyl Cellulose powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt–ice mixes.
Sodium CarboxyMethyl Cellulose is used in baking breads and cakes.
The use of Sodium CarboxyMethyl Cellulose gives the loaf an improved quality (e.g., texture) at a reduced cost by reducing the need for fat.
Sodium CarboxyMethyl Cellulose is also used as an emulsifier in sweet biscuits.
Dispersing fat uniformly in the dough improves the release of the dough from the molds and cutters, achieving well-shaped biscuits without any distorted edges.
Sodium CarboxyMethyl Cellulose can also help to reduce the amount of egg yolk or fat used in making the biscuits.
The use of Sodium CarboxyMethyl Cellulose in candy preparation ensures smooth dispersion in flavor oils and improves texture and quality.
Sodium CarboxyMethyl Cellulose is used in chewing gums, margarine, and peanut butter as an emulsifier.
Detergent uses
Sodium CarboxyMethyl Cellulose is a common ingredient in cleaning products because of its thickening and stabilizing properties and nontoxic composition.
In detergent and cleaning products, Sodium CarboxyMethyl Cellulose can be used to enhance texture and assist in the suspension of dirt and grime in the cleaning product.
Sodium CarboxyMethyl Cellulose's adjustable viscosity can be used to standardize the textures of the products, especially when used along with other chemicals.
Sodium CarboxyMethyl Cellulose helps with the removal of grease and aids in the creation of small bubbles in the soap.
This, along with its ability to suspend dirt in mixtures, can make soaps and other cleaning products more efficient.
Textile uses
Sodium CarboxyMethyl Cellulose is used in textiles as a thickening agent in textile printing, constituting about 2-3% of printing pastes.
Sodium CarboxyMethyl Cellulose is also used in fabric finishing to affect the fabric's texture.
Additionally, Sodium CarboxyMethyl Cellulose serves as a binding agent in non-woven fabrics, contributing to the strength and stability of the material.
In sizing applications, about 1-3% of Sodium CarboxyMethyl Cellulose is used to protect yarns during weaving to reduce breakages.
Sodium CarboxyMethyl Cellulose aids in thickening printing pastes, which makes the prints themselves more precise.
Sodium CarboxyMethyl Cellulose is also used to thicken dyes.
Additionally, Sodium CarboxyMethyl Cellulose is an alternative to synthetic thickeners.
Cosmetics uses
Sodium CarboxyMethyl Cellulose is an ingredient used in over 50% of cosmetic products.
As a thickening agent, Sodium CarboxyMethyl Cellulose is used in formulations where viscosity needs to be precisely controlled.
In hair care, about 25% of shampoos and conditioners utilize Sodium CarboxyMethyl Cellulose for its conditioning and detangling effects.
Sodium CarboxyMethyl Cellulose is also used in the makeup and toothpaste industries to control the products' texture.
Due to its ability to retain moisture, Sodium CarboxyMethyl Cellulose is also used in skincare products.
Sodium CarboxyMethyl Cellulose serves as a film-forming agent in approximately 10% of sunscreens.
Sodium CarboxyMethyl Cellulose aids in pigment suspension and dispersion, binding other ingredients for even distribution.
Sodium CarboxyMethyl Cellulose, when combined with Fatty Acid Ethanolamine or 2,2'-Iminodiethanol in a hair product, can form a thin film around the hair.
Preparation
Sodium CarboxyMethyl Cellulose is synthesized by the alkali-catalyzed reaction of cellulose with chloroacetic acid.
The polar (organic acid) carboxyl groups render the cellulose soluble and chemically reactive.
Fabrics made of cellulose – e.g., cotton or viscose (rayon) – may also be converted into Sodium CarboxyMethyl Cellulose.
Following the initial reaction, the resultant mixture produces approximately 60% Sodium CarboxyMethyl Cellulose and 40% salts (sodium chloride and sodium glycolate).
This product, called technical Sodium CarboxyMethyl Cellulose, is used in detergents, where Sodium CarboxyMethyl Cellulose is used as a thickening agent.
An additional purification process is used to remove salts to produce pure Sodium CarboxyMethyl Cellulose, which is used for food and pharmaceutical applications.
An intermediate 'semi-purified' grade is also produced, which is typically used in paper applications such as the restoration of archival documents.