PRODUCTS

SODIUM DEHYDROACETATE

Sodium Dehydroacetate is used in the food industry in some countries.
Sodium Dehydroacetate is used Conservative in the formulas containing an aqueous phase.
Sodium Dehydroacetate is used any product containing an aqueous phase and whose pH is between 2.0 and 6.5.

CAS Number: 4418-26-2
EC Number: 224-580-1
MDL Number: MFCD00040583
Chem/IUPAC Name: Sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolate
Molar mass: 190.130 g·mol−1
Molecular Formula: C8H7O4.Na / C8H7NaO4

SYNONYMS:
Harven, Prevan, DHA-sodium, Caswell No. 278A, New Side S 01, Dehydroacetic acid, sodium salt, DHA-S, CCRIS 1895, HSDB 4236, dehydroacetic acid sodium, EINECS 224-580-1, EPA Pesticide Chemical Code 027802, Sodium dehydroacetate (NF), Sodium dehydroacetate [NF], Dehydroacetic acid (sodium), Sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolate, Kyselina dehydroacetova sodna sul [Czech], Sodium 3-acetyl-6-methyl-2,4-pyrandione, UNII-8W46YN971G, Kyselina dehydroacetova sodna sul, 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, ion(1-), sodium, 8W46YN971G, Sodium 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione, 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium salt, 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, sodium salt, 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, monosodium salt, 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, ion(1-), sodium salt, 3-(1-Hydroxyethylidene)-6-methyl-2H-pyran-2,4(3H)-dione, sodium salt, 4-Hexenoic acid, 2-acetyl-5-hydroxy-3-oxo, delta-lactone, sodium derivative, 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium, DHAsodium, SCHEMBL41961, SCHEMBL1532492, YIOCQGHBBNGBND-UHFFFAOYSA-N, Sodium 3acetyl6methyl2,4pyrandione, SODIUM DEHYDROACETATE [INCI], 3-(1-hydroxyethylidene)-6-methyl-2H-pyran-2,4(3H)-dione sodium salt, AKOS024462917, Dehydroacetic acid (sodium) (Standard), HY-128467R, DEHYDROACETIC ACID, SODIUM DERIV., 3Acetyl6methyl2Hpyran2,4(3H)dione sodium, Sodium 3acetyl6methyl2Hpyran2,4(3H)dione, HY-128467, CS-0099505, 3Acetyl6methyl2Hpyran2,4(3H)dione sodium salt, D05856, F71232, sodium 3-acetyl-6-methyl-4-oxo-4H-pyran-2-olate, 2HPyran2,4(3H)dione, 3acetyl6methyl, sodium salt, 2HPyran2,4(3H)dione, 3acetyl6methyl, ion(1), sodium, 2HPyran2,4(3H)dione, 3acetyl6methyl, ion(1), sodium salt, 3(1Hydroxyethylidene)6methyl2Hpyran2,4(3H)dione, sodium salt, 4Hexenoic acid, 2acetyl5hydroxy3oxo, deltalactone, sodium derivative, 2H-PYRAN-2,4(3H)-DIONE, 3-ACETYL-6-METHYL-, ION(1-) SODIUM, 2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, ion(1-), sodium (1:1), 4-HEXENOIC ACID, 2-ACETYL-5-HYDROXY-3-OXO-, DELTA-LACTONE, SODIUM DERIV., dehydroacetic, dhn, DEHYDROACETIC ACID SODIUM SALT, Sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolate, NaDHA, harven, prevan, SODIUMDHA, dha-sodium, New Side S 01, 2-acetyl-5-hydroxy-3-oxo-4-henenoic acid delta-lactone sodium, 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium, dehydroacetic acid sodium salt, fenexol (Vevy), harven, 2H-pyran-2,4(3H)-dione, 3-(1-hydroxyethylidene)-6-methyl-, sodium salt (1:1), sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolate, sodium 1-(6-methyl-2,4-dioxo-2H-pyran-3(4H)-ylidene)ethanolate, sodium 3-acetyl-6-methyl-2,4-pyrandione, sodium 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione, sodium 3-acetyl-6-methylpyran-3-ide-2,4-dione, sodium dehydroacetic acid,

Sodium dehydroacetate is a compound with the formula Na(CH3C5HO(O2)(CH3)CO).
Sodium Dehydroacetate is the sodium salt of dehydroacetic acid.
Sodium Dehydroacetate is used as a preservative in food, cosmetics and personal care products such as shower gels, which is highly effective against a broad range of bacteria even at low concentrations such as 0.075 g/kg in meat.

Sodium dehydroacetate is the sodium salt of dehydroacetate.
Sodium Dehydroacetate is mainly used as a new generation food preservative and food additive, being used extensively in sauce, fruit, bread, cake, moon cake, margarine and beverage.

Sodium Dehydroacetate is a white-to-yellowish powder
Sodium Dehydroacetate is a white powder.
Sodium Dehydroacetate has E number E266.

Sodium dehydroacetate is a white powder.
The sodium salt of dehydroacetate is sodium dehydroacetate.
Sodium Dehydroacetate is a tasteless, odorless, white powder that is soluble in water.

Sodium Dehydroacetate is the sodium salt of Dehydroacetic acid.
Sodium Dehydroacetate is a paraben and formaldehyde-free preservative used in cosmetics and personal care products due to its antimicrobial and antifungal properties.

Sodium Dehydroacetate functions primarily by prohibiting the growth of bacteria and fungus, although it may not necessarily kill already developed microbes.
Thus, careful attention should be paid to good production hygiene, as well as the use of raw materials with low microorganism levels, as these are vital prerequisites for the production of well preserved products.

In the USA, Sodium Dehydroacetate has been reviewed by the Cosmetic Ingredient Review (CIR) Expert Panel and is considered safe as a cosmetic ingredient in its present practices of use and concentration.
Sodium dehydroacetate is the sodium salt of dehydroacetic acid, a fungicide and bactericide that is commonly used as a food preservative.

Sodium dehydroacetate is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.
Dehydroacetic Acid and Sodium Dehydroacetate are tasteless, odorless white powders.

Sodium Dehydroacetate is water-soluble for cosmetics and toiletries (leave-on and rinse-off products).
Sodium dehydroacetate is a white powdery substance with antimicrobial action.
Sodium Dehydroacetate is particularly effective against yeast and mould.

Sodium Dehydroacetate is highly soluble in water.
Sodium Dehydroacetate is approved for use in the USA and Japan.
According to EU Regulation 1223/2009 and CU TR 009/2011, the maximum permissible concentration of sodium dehydroacetate in cosmetics is 0.6% in terms of free acid.

Sodium Dehydroacetate's use in aerosols is prohibited.
Sodium Dehydroacetate is a white or off-white crystalline powder, with a solubility of (25℃,g/100g): ethanol 1; propanediol 48; glycerin 15; water 33; acetone 0.2. It is soluble in water and has a pH value of 1% aqueous solution is 8.

Sodium Dehydroacetate has a broad-spectrum antibiotic action, strong bacteriostatic capability.
Sodium Dehydroacetate has wide range for bacteriostasis and is not affected by pH values.
Whatever under acidic, neutral and alkaline condition, Sodium Dehydroacetate has a good effect and strong inhibition capacity especially for mold, yeast and bacteria, and the concentration of effective working is low.

Sodium Dehydroacetate has heat resistance and its light resistance is good.
Sodium Dehydroacetate will not be decomposed and evaporated with steam during food production.
The testing proved that Sodium Dehydroacetate is almost nontoxic and safe, with no abnormal flavor produced from the process of using in food, so it can prevent from rancidness, and extend the storage time.

Sodium Dehydroacetate is a helper ingredient that helps to make the products stay nice longer, aka preservative.
Sodium Dehydroacetate works mainly against fungi and has only milder effect against bacteria.
Sodium Dehydroacetate is Ecocert and Cosmos approved, and is popular in natural products.

Sodium dehydroacetate, a white crystalline powder with a slight odor, is the sodium salt of dehydroacetic acid obtained by a synthetic process.
Sodium Dehydroacetate has antimicrobial and anti-mould activity and acts against both Gram negative and Gram positive bacteria.
Sodium dehydroacetate is a preservative.

Sodium Dehydroacetate is sodium salt of dehydroacetic acid suitable for cosmetic applications.
Sodium dehydroacetate is an organic salt used in low amounts as a preservative to prevent formulary spoilage.

USES and APPLICATIONS of SODIUM DEHYDROACETATE:
Preservative: Sodium Dehydroacetate is widely used in cosmetics, personal care products, and food to inhibit microbial growth.
Antimicrobial Agent: Sodium Dehydroacetate is effective against bacteria, fungi, and yeast.
Food Additive (E266): Sodium Dehydroacetate is approved as a preservative for certain food products.

Cosmetic Ingredient: Sodium Dehydroacetate extends shelf life by preventing microbial contamination.
Pharmaceutical Applications: Sodium Dehydroacetate is used as a stabilizer in certain drug formulations.
Use in Cosmetic and Personal Care Products: Sodium dehydroacetate is also used in the formulations of makeup, skin, and hair care products.

Sodium dehydroacetate is used in the food industry as a preservative for fruits, vegetables, fruit juice, honey, beer, milk, protein and fat products.
Sodium Dehydroacetate's antimicrobial properties play a vital role in personal care products such as skin care, suntan, sunscreen, shaving, tooth paste, hair and nail care products, and eye and facial makeup.

Sodium Dehydroacetate is used as a plasticizer.
Sodium Dehydroacetate is used in the food industry as preservative for fruits, vegetables, fruit juice, honey, beer, milk, protein and fat products; in human and veterinary medicine as bactericide and fungicide.

Sodium Dehydroacetate preservative is based on dehydroacetic acid (DHA), the sodium salt form (NaDHA) and therefore are recognized by major cosmetic, toiletry and fragrance regulatory authorities worldwide for use in cosmetic and personal care products.
Sodium Dehydroacetate is a preservative against bacteria and fungi that is used at concentration levels of 1.0 percent or less.

Sodium Dehydroacetate is useful in combination with parabens.
Sodium dehydroacetate is the sodium salt of dehydroacetate.
Sodium dehydroacetate is an antimicrobial ingredient used as preservative.

Sodium Dehydroacetate is mainly used as a new generation food preservative and food additive, being used extensively in sauce, fruit, bread, cake, moon cake, margarine and beverage.
Sodium Dehydroacetate is used as a fungicide, plasticizer, toothpaste, preservative in food.

Sodium dehydroacetate (DHA-S) has a wide spectrum of antimicrobial activity that accounts for its use in cosmetic products as a preservative and antimicrobial agent.
Sodium Dehydroacetate is effective in the treatment of both bacteria and fungi.

Sodium Dehydroacetate is also a kind of anticoagulant agent through depleting the blood level of vitamin K.
Its use is regulated in China, Japan and the USA, thus Sodium Dehydroacetate can only be used in certain foods such as picked vegetables, fermented soy, compound seasonings and pickled mushrooms in China, and only peeled pumpkins in the US at 65 parts per million.

Sodium Dehydroacetate is not approved for use in the EU.
Sodium Dehydroacetate adds an acetic odor to food which can be mitigated using flavorings.
Sodium Dehydroacetate can also be used in bread and pastries.

Sodium Dehydroacetate is highly effective when applied to oranges.
Sodium Dehydroacetate is a preservative used in cosmetics and personal care products because of its antimicrobial properties.
Sodium Dehydroacetate is considered to be an effective antimicrobial and preservative even at very low concentrations, prohibiting the growth of bacterial and fungal microbes.

Sodium Dehydroacetate is used as a fungicide, plasticizer, toothpaste, preservative in food.
In cosmetics and personal care products, Dehydroacetic Acid and Sodium Dehydroacetate are used in the formulation of a wide variety of products, including bath, skin care, suntan, sunscreen, fragrance, shaving, hair and nail care products, as well as eye and facial makeup.

Sodium Dehydroacetate is used as a preservative in cosmetic products.
Sodium Dehydroacetate is used in toothpastes, including anti-plaque, shampoos, hygiene lotions, etc.
Sodium Dehydroacetate is approved for use in the EU, USA and Japan.

Its effectiveness depends a lot on the pH which must be between 5 and 6.5 and in cosmetics Sodium Dehydroacetate is used as a preservative in most cosmetic preparations, except for spray products.
Sodium Dehydroacetate is used with a maximum concentration of 0.6%.

Sodium dehydroacetate is a preservative used in cosmetics for its antimicrobial properties.
Sodium dehydroacetate, is a preservative active ingredient widely used in cosmetic and toiletries formulations.
Sodium Dehydroacetate is highly effective against fungi and yeasts and offers stronger efficacy compared to many other conventional preservatives.

The efficacy of Sodium Dehydroacetate depends on the pH value of the cosmetic formulations (pH max. 6).
The efficiency is increased by lowering the pH value.
Only the free organic acid form has a preservative effect.

Sodium Dehydroacetate is often used for faster incorporation due to its better solubility in aqueous formulations.
Sodium Dehydroacetate can be found in a variety of products including bath, skin care, suntan, sunscreen, wet wipes, facial masks, fragrance, shaving, hair and nail care products, and eye and facial makeup.

USES & BENEFITS OF SODIUM DEHYDROACETATE:
*Food Preservative and Additive:
Sodium dehydroacetate is primarily used as a new generation food preservative and food additive.
Sodium Dehydroacetate is widely employed in sauces, fruits, breads, cakes, mooncakes, margarine, and beverages.

*Antimicrobial Agent:
Sodium dehydroacetate (DHA-S) has a broad spectrum of antibacterial activity, which accounts for its application as a preservative and antimicrobial agent in cosmetic products.
Sodium Dehydroacetate is efficient against bacteria as well as fungi.

*Anticoagulant Agent:
Sodium dehydroacetate also acts as an anticoagulant agent by lowering vitamin K levels in the blood.

*Extensive Use in Food and Beverages:
Sodium dehydroacetate is extensively used as a preservative in food and beverages.
As a preservative, Sodium Dehydroacetate inhibits the growth of molds, fungi, or bacteria in the product.

Sodium Dehydroacetate increases the shelf life of the product so that aroma, taste, and the cosmetics themselves can be stored for a longer period of time.
Sodium Dehydroacetate protects the product from deteriorating over time.

PROPERTIES OF SODIUM DEHYDROACETATE:
*Antifungal,
*antibacterial.

BENEFITS OF SODIUM DEHYDROACETATE:
*Paraben Free
*Antimicrobial Properties
*Ease of formulating due to low required use level and water solubility.

PROPERTIES OF SODIUM DEHYDROACETATE:
*Broad-Spectrum Antimicrobial:
Effective against a wide range of microorganisms.

*Water Solubility:
Allows easy incorporation into aqueous systems.

*Mild Nature:
Non-irritating and non-sensitizing to skin under recommended concentrations.

*Thermal Stability:
Remains effective under a range of temperatures.

*Low Toxicity:
Safe for use in regulated concentrations.

BENEFITS OF SODIUM DEHYDROACETATE:
*Sodium Dehydroacetate enhances product shelf life by preventing microbial contamination.
*Sodium Dehydroacetate reduces the need for additional preservatives in formulations.
*Compatible with a wide range of cosmetic and food formulations.
*Sodium Dehydroacetate provides a safer alternative to other synthetic preservatives.
*Approved by regulatory authorities like the FDA and EU for specific uses.

WHAT DOES SODIUM DEHYDROACETATE DO IN A FORMULATION?
*Preservative

SOLUBILITY OF SODIUM DEHYDROACETATE:
Sodium Dehydroacetate is soluble in water, propylene glycol and methanol.
Sodium Dehydroacetate is insoluble in acetone and benzene.

NOTES OF SODIUM DEHYDROACETATE:
Sodium Dehydroacetate is incompatible strong oxidizing agents and acids.

REACTIVITY PROFILE OF SODIUM DEHYDROACETATE:
Reactivity Profile
Sodium dehydroacetate reacts with acids.
Sodium Dehydroacetate may react viogrously with strong oxidizing acids.

WHY IS SODIUM DEHYDROACETATE USED?
Sodium Dehydroacetate and Dehydroacetic Acid kill microorganisms and prevent their growth and reproduction, thus protecting cosmetics and personal care products from spoilage.

SCIENTIFIC FACTS OF SODIUM DEHYDROACETATE:
The antimicrobial properties of Dehydroacetic Acid and Sodium Dehydroacetate have led to their widespread use in cosmetics and personal care products.
These ingredients are also used as preservatives in glue and cleaning solutions.

PHYSICAL and CHEMICAL PROPERTIES of SODIUM DEHYDROACETATE:
SMILES: CC(C-C(C=C1C)=O)=O.[Na+]
Physical state: powder
Color: beige
Odor: No data available
Melting point/freezing point:
Melting point: > 280 °C at ca.1.013 hPa
Decomposes before melting.
Initial boiling point and boiling range: 269.9 °C
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available

Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity: Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 231 g/l at 20 °C
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available

Relative density: 1.49 at 20 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 109.00 to 111.00 °C. @ 760.00 mm Hg
Flash Point: 32.00 °F. TCC (0.00 °C.) (est)
Soluble in: water, 9.134e+004 mg/L @ 25 °C (est)

INCI Nomenclature: Sodium Dehydroacetate
Appearance: Powder
Color: White to slightly yellow
Solubility: Water Soluble
Suggested Use Levels: 0.03-0.5%
Suggested Applications: Rinse off products, skincare, and body care.
Storage: Store away from heat and strong oxidizing agents in tightly closed storage.
Chemical Name: Sodium 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione
Appearance: White to slightly yellow crystalline powder.
Molecular Formula: C8H7NaO4

Molecular Weight: 190.13 g/mol
Melting Point: Decomposes before melting.
Solubility: Highly soluble in water, slightly soluble in ethanol.
pH: 6.0–9.0 (1% aqueous solution).
Stability: Stable under normal storage conditions, sensitive to strong acids and bases.
CBNumber: CB4390163
Molecular Formula: C8H7NaO4
Molecular Weight: 190.13
MDL Number: MFCD00040583
MOL File: 4418-26-2.mol

Melting point: ~295 °C (dec.)
Density: 1.499[at 20℃]
Vapor pressure: 0Pa at 25℃
Storage temp.: Store below +30°C.
Solubility: 330g/l
pKa: 5.36[at 20 ℃]
Form: Powder
Color: White to yellow
pH: 8.8-9.3 (100g/l, H2O, 20℃)

Water Solubility: Soluble in water, propylene glycol and methanol.
Insoluble in acetone and benzene.
BRN: 4893653
Stability: Stable.
Incompatible with strong oxidizing agents.
InChIKey: ZPNRBQVNNIDJHX-UHFFFAOYSA-M
LogP: -4.38 at 20℃
Substances Added to Food (formerly EAFUS): SODIUM DEHYDROACETATE
FDA 21 CFR: 175.105
CAS DataBase Reference: 4418-26-2(CAS DataBase Reference)

EWG's Food Scores: 1
FDA UNII: 8W46YN971G
EPA Substance Registry System: 3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium (4418-26-2)
IUPAC Name: sodium 3-acetyl-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
Molecular Formula: C8H7NaO4
InChI Key: YIOCQGHBBNGBND-UHFFFAOYSA-N
SMILES: [Na+].CC(=O)[C-]1C(=O)OC(C)=CC1=O
Molecular Weight (g/mol): 190.13
Synonym: sodium dehydroacetate
CAS: 4418-26-2

Appearance (Color): White to pale cream
Form: Powder
Assay (Non-aqueous acid-base Titration): ≥96.0 to ≤104.0%
Molecular Weight: 190.13
Formula: C8H7NaO4
CAS No.: 4418-26-2
Appearance: Solid
Color: Off-white to yellow
CAS Number: 4418-26-2
Interactive image
ECHA InfoCard: 100.022.347

E number: E266 (preservatives)
Chemical formula: C8H7NaO4
Molar mass: 190.130 g·mol−1
Molecular Weight: 190.13 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 1
Exact Mass: 190.02420298 Da
Monoisotopic Mass: 190.02420298 Da
Topological Polar Surface Area: 60.4 Å²

Heavy Atom Count: 13
Formal Charge: 0
Complexity: 293
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

FIRST AID MEASURES of SODIUM DEHYDROACETATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Remove contact lenses.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of SODIUM DEHYDROACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.

FIRE FIGHTING MEASURES of SODIUM DEHYDROACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available

EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM DEHYDROACETATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SODIUM DEHYDROACETATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

STABILITY and REACTIVITY of SODIUM DEHYDROACETATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available