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SODIUM L-ASCORBATE

 

 

Sodium L-ascorbate is used as antimicrobial and antioxidant in foodstuffs.
Sodium L-ascorbate is used as an antioxidant, an acidity regulator and an antimicrobial in food stuffs.
Sodium L-ascorbate acts as a coenzyme for many hydroxylation reactions.


CAS Number: 134-03-2 
EC Number: 205-126-1
MDL Number:MFCD00082340
E number: E301 (antioxidants, ...)
Chemical formula: C6H7NaO6
Molecular Formula: C6H7O6.Na / C6H7O6Na 
Molar mass: 198.106 g•mol−1

SYNONYMS:
L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt, L-Ascorbic acid sodium salt, Sodium ascorbate, Natrii ascorbas, (+)-Sodium L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, sodium ascorbate, l-ascorbic acid sodium salt, sodium l-ascorbate, vitamin c sodium, ascorbicin, sodascorbate, cebitate, aminofenitrooxon, natrii ascorbas, monosodium l-ascorbate, SODIUM L-ASCORBATE, L-ASCORBIC ACID SODIUM SALT, SodiuM ascorbat, Sodium Ascorbate Powder, cebitate, VITAMIN C SODIUM, VITAMINE C SODIUM SALT, L-ASCORBIC ACID SODIUM, SODIUM ASCORBATE 97% GRANULATION, Sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Vitamin C sodium salt, Ascorbate sodium salt, Sodium ascorbate, L-Xyloascorbic acid, 3-Oxo-L-gulofuranolactone (enol form), L-3-Ketothreohexuronic acid lactone, Antiscorbutic vitamin, Cevitamic acid, Sodascorbate, Monosodium Ascorbate, Ascorbicin, L(+)-Ascorbic acid sodium salt, (+)-Sodium L-ascorbate, vitamin C sodium, Sodium ascorbate, Vitamine C sodium salt, L-ASCORBIC ACID NA-SALT, ASCORBIC ACID SODIUM SALT, SODIUMASCORBATE,POWDER,USP, L-ASCORBIC ACID SODIUM SALT, L-Ascorbic Acid Sodium Salt, SODIUMASCORBATE,GRANULAR,FCC, SODIUMASCORBATE,GRANULAR,USP, L(+)-ASCORBIC ACID SODIUM SALT, SODIUM ASCORBATE (VC-NA) AND ITS DIRECTLY-COMPRESSION GRANULE, sodium 2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate (non-preferred name), sodium 5-(1,2-dihydroxyethyl)-3-hydroxy-4-oxo-4,5-dihydrofuran-2-olate (non-preferred name), sodium 5-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-oxo-4,5-dihydrofuran-2-olate (non-preferred name), Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate, Sodascorbate; Monosodium ascorbate, E301, (+)-Sodium L-ascorbate, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt, SODIUM ASCORBATE, 134-03-2, Sodium L-ascorbate, L-Ascorbic acid sodium salt, Vitamin C sodium, Monosodium L-ascorbate, Ascorbicin, Ascorbic acid sodium salt, Natrii ascorbas, Vitamin C Sodium Salt, Iskia-C, Natri-C, Ascorbate de sodium, Sodascorbate, (+)-Sodium L-ascorbate, L-Ascorbic acid, monosodium salt, Vitamin C, sodium salt, ascorbate, Ascorbin, Cevalin, L-Ascorbic acid sodium, 3-Oxo-L-gulofuranolactone sodium, MFCD00082340, INS NO.301, L(+)-Ascorbic acid sodium salt, INS-301, S033EH8359, L-Ascorbic acid (sodium salt), DTXSID0020105, E-301, CHEBI:113451, l-Ascorbate, sodium, Sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Cebitate, Aminofenitrooxon, sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate, sodium (L)-ascorbate, sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, SODIUM ASCORBATE (II), SODIUM ASCORBATE [II], SODIUM ASCORBATE (MART.), SODIUM ASCORBATE [MART.], sodiumascorbate, SODIUM ASCORBATE (USP-RS), SODIUM ASCORBATE [USP-RS], Ascorbato sodico, Ascorbato sodico [DCIT], SODIUM ASCORBATE (EP MONOGRAPH), SODIUM ASCORBATE [EP MONOGRAPH], SODIUM ASCORBATE (USP MONOGRAPH), SODIUM ASCORBATE [USP MONOGRAPH], Monosodium Ascorbate, Ascorbic acid sodium derivative, CCRIS 3291, HSDB 694, HBL 508, EINECS 205-126-1, Tianafacacid, Sodium ascorbate [USP:INN], UNII-S033EH8359, Sodium derivative of 3-oxo-L-gulofuranolactone, Ascorbate, Sodium, sodium (2R)-2-((1S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Sodium ascorbate, Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, (+)-Sodium L-ascorbate ,Vitamin C sodium salt;Sodium L-ascorbate, E301, sodium L-ascorbate salt, VITA-JEC C, EC 205-126-1, SCHEMBL3745, ASK-P 10KR, DTXCID60105, L(+)Ascorbic acid sodium salt, HY-B0166A, PPASLZSBLFJQEF-RXSVEWSESA-M, SODIUM ASCORBATE [WHO-DD], L-Ascorbic Acid Sodium Salt,(S), Tox21_300556, AKOS015895058, L-Ascorbic acid, sodium salt (1:1), SODIUM ASCORBATE [ORANGE BOOK], ASCORBIC ACID SODIUM SALT [MI], CS-6063, DB14482, 3-Keto-L-gulofuranlactone sodium enolate, NCGC00254355-01, BP-30077, CAS-134-03-2, A0539, E80761, EN300-221566, A806721, Q424551, J-006471, 2,3-Didehydro-L-theo-hexono-1,4-lactone sodium enolate, Z1255486556, sodium (2R)-2-[(1S)-1,2-bis(oxidanyl)ethyl]-4-oxidanyl-5-oxidanylidene-2H-furan-3-olate, Sodium(R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, sodium;(2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate, (+)-Sodium L-ascorbate, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt, Vitamin C Sodium, Ascorbic Acid Sodium Salt, Monosodium L-Ascorbate, SODIUM L-ASCORBATE,L-ASCORBIC ACID SODIUM SALT,SodiuM ascorbat,Sodium Ascorbate Powder,cebitate,VITAMIN C SODIUM,VITAMINE C SODIUM SALT,L-ASCORBIC ACID SODIUM,SODIUM ASCORBATE 97% GRANULATION,Sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, L-Ascorbic Acid sodium salt, 134-03-2, Vitamin C, Sodium Salt, Na-L-Ascorbate, Mono Na-L Ascorbate, Tablet Grade Ascorbate, E301, Sodium L-ascorbate, Vitamin C sodium salt, L(+)-Ascorbic acid sodium salt, Monosodium ascorbate, Ascorbic acid sodium salt, (+)-Sodium L-ascorbate, L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt, Ascorbic acid sodium salt, Ascorbicin, Ascorbin, Cebitate, Cenolate, Iskia C, L-Ascorbic acid monosodium salt, Monosodium L-ascorbate, (+)-Sodium L-ascorbate, L-Ascorbic acid sodium salt, Monosodium ascorbate, Sodium ascorbate, Vitamin C sodium salt, Ascorbic acid sodium salt, L-Ascorbic acid monosodium salt, Natrii ascorbas, Sodascorbate, Sodium L-ascorbate, Natrium ascorbat, Ascorbate de sodium, Ascorbato de sodio, Natrascorb, Cebitate, Cenolate, Iskia-C, Xitix, Ascorbicin, Ascorbin, Sodiumascorbate, Vitamin C sodium, VITAMIN C SODIUM, Vitamin- C sodium salt, sodium ascorbate, Sodium L-ascorbate, L-Ascorbic acid sodium salt, Vitamin C sodium salt, Monosodium ascorbate, Sodium 5-(1,2-dihydroxyethyl)-3-hydroxy-4-oxo-furan-2-olate, Ascorbic acid Na salt, Vitamin C Na salt

Sodium L-ascorbate is a more bioavailable form of vitamin C that is an antioxidant agent.
Sodium L-ascorbate, an electron donor, is an endogenous antioxidant.
Sodium L-ascorbate selectively inhibits Cav3.2 channels with an IC50 of 6.5 μ.


Sodium L-ascorbate also promotes collagen deposition and inhibits elasticity production.
Sodium L-ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C), which is approved for use as a food additive in many countries.
Sodium L-ascorbate occurs as a white or slightly yellow-colored, practically odorless, crystalline powder with a pleasant saline taste.


Sodium L-ascorbate is an antioxidant that is the sodium form of ascorbic acid.
Sodium L-ascorbate is soluble in water and provides a nonacidic taste.
Sodium L-ascorbate is a 10% aqueous solution has a pH of 7.3–7.6.


In water, Sodium L-ascorbate readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant.
One part Sodium L-ascorbate is equivalent to 1.09 parts of sodium erythorbate.
Sodium L-ascorbate is a minute crystals or white powder.


pH of aqueous solutions of Sodium L-ascorbate is 5.6 to 7.0 or even higher (a 10% solution, made from a commercial grade, may have a pH of 7.4 to 7.7).
Sodium L-ascorbate is an organic sodium salt resulting from the replacement of the proton from the 3-hydroxy group of ascorbic acid by a sodium ion.


Sodium L-ascorbate has a role as a food antioxidant, a flour treatment agent, a coenzyme, a plant metabolite, a human metabolite, a Daphnia magna metabolite and a reducing agent.
Sodium L-ascorbate is an organic sodium salt and a vitamin C.


Sodium L-ascorbate contains a L-ascorbate.
Sodium L-ascorbate, an electron donor, is an endogenous antioxidant agent.
Sodium L-ascorbate selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM.


Sodium L-ascorbate is also a collagen deposition enhancer and an elastogenesis inhibitor.
Sodium L-ascorbate is a highly effective and versatile compound, widely recognized for its role as a stable form of vitamin C.
Sodium L-ascorbate is a white to slightly yellow crystalline powder, soluble in water.


Sodium L-ascorbate is derived from ascorbic acid by replacing a hydrogen atom with a sodium ion.
Sodium L-ascorbate is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress.


Sodium L-ascorbate is a salt form of ascorbic acid, known as vitamin C.
Chemically, Sodium L-ascorbate is known for its strong antioxidant properties and its ability to participate in redox reactions. 
Sodium L-ascorbate converts readily between reduced and oxidized forms, making it effective in biochemical pathways that require electron donation. 


While Sodium L-ascorbate contains sodium, the amount contributed in typical supplement doses is generally small; however, individuals on sodium-restricted diets may need to monitor intake. 
Sodium L-ascorbate (C6H7NaO6) is the sodium salt form of vitamin C that is more easily absorbed than ascorbic acid.


Sodium L-ascorbate can be given as an injection.
Sodium L-ascorbate is also found in osmotic laxatives indicated for cleansing of the colon as a preparation for colonoscopy.
Sodium L-ascorbate may also be found as an ingredient in other pharmaceutical products.


Sodium L-ascorbate can also be used as a food additive and is listed on the FDA list of generally recognized as safe (GRAS) substances.
Sodium L-ascorbate, an electron donor, is an endogenous antioxidant agent.
Sodium L-ascorbate selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM.


Sodium L-ascorbate is also a collagen deposition enhancer and an elastogenesis inhibitor.
Sodium L-ascorbate is a sodium salt of ascorbic acid.
Sodium L-ascorbate is the sodium salt of ascorbic acid, a buffered and less acidic form of vitamin C that is widely used in medicine, food technology, and nutritional supplements. 


Because Sodium L-ascorbate is pH-neutral or slightly basic, it is much gentler on the stomach than pure ascorbic acid and is often chosen by people who experience digestive irritation with regular vitamin C. 
Sodium L-ascorbate dissolves quickly in water and forms a clear, stable solution that maintains strong antioxidant activity. 


In its solid form, Sodium L-ascorbate typically appears as a white to pale yellow crystalline powder that decomposes slowly when exposed to light, heat, or moisture.
Sodium L-ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).


The molecular formula of Sodium L-ascorbate is C6H7NaO6.
As the sodium salt of ascorbic acid, Sodium L-ascorbate is known as a mineral ascorbate.
Sodium L-ascorbate has not been demonstrated to be more bioavailable than any other form of vitamin C supplement.


Sodium L-ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of Sodium L-ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).
Sodium L-ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand.


pH of aqueous solutions of Sodium L-ascorbate is 5.6 to 7.0 or even higher (a 10% solution, made from a commercial grade, may have a pH of 7.4 to 7.7).
Sodium L-ascorbate is an organic sodium salt resulting from the replacement of the proton from the 3-hydroxy group of ascorbic acid by a sodium ion.


Sodium L-ascorbate has a role as a food antioxidant, a flour treatment agent, a coenzyme, a plant metabolite, a human metabolite, a Daphnia magna metabolite and a reducing agent.
Sodium L-ascorbate is an organic sodium salt and a vitamin C.


Sodium L-ascorbate contains a L-ascorbate.
Sodium L-ascorbate is a small molecule drug with a maximum clinical trial phase of IV (across all indications).

USES and APPLICATIONS of SODIUM L-ASCORBATE:
Sodium L-ascorbate is consisted of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry.
In this mixture, sodium acts as a buffer, creating a less acidic supplement than those made entirely from vitamin C.


Sodium L-ascorbate can be easier to tolerate if the digestive system is sensitive to acid.
As a vitamin C supplement, Sodium L-ascorbate provides both sodium and vitamin C for human body, which is effective to prevent or treat vitamin C deficiency.


Besides, studies have shown that taking Sodium L-ascorbate is helpful with cancer prevention and treatment.
Sodium L-ascorbate is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress.


Sodium L-ascorbate is used as antimicrobial and antioxidant in foodstuffs.
Sodium L-ascorbate is suitable for battery materials development.
Sodium L-ascorbate is used as an antioxidant, an acidity regulator and an antimicrobial in food stuffs.


As a reductant, Sodium L-ascorbate is involved in the isolation of chloroplasts.
Sodium L-ascorbate acts as a coenzyme for many hydroxylation reactions.
Sodium L-ascorbate plays a vital role to eliminate chronic and acute infections.


Sodium L-ascorbate finds applications as an additive in curing meat products such as ham and sausage meat.
Sodium L-ascorbate is widely used as a nutritional supplement in agriculture and animal feed to promote the growth of young animals and prevent scurvy.


Sodium L-ascorbate is also used as an intermediate in the manufacture of various organic chemicals.
Sodium L-ascorbate retains the antioxidant properties of ascorbic acid while being more soluble in water, thanks to the presence of sodium.
This increased solubility makes Sodium L-ascorbate especially useful in various applications where vitamin C′s water solubility is a limiting factor.


Sodium L-ascorbate acts as a potent antioxidant, scavenging free radicals and thus protecting cells from oxidative damage.
This activity is in many biological processes, including the synthesis of collagen, the absorption of iron, and the maintenance of the immune system.


Sodium L-ascorbate is utilized extensively in the food and pharmaceutical industries due to its antioxidant properties, which help in preserving the quality and extending the shelf life of products.
Its ability to scavenge free radicals makes Sodium L-ascorbate an essential ingredient in dietary supplements, functional foods, and cosmetics, where it contributes to skin health and overall wellness.


In addition to its preservative qualities, Sodium L-ascorbate is also employed in various biochemical applications, including cell culture and laboratory research, where it serves as a reducing agent and a co-factor in enzymatic reactions.
Its unique solubility in water enhances its bioavailability, making Sodium L-ascorbate an ideal choice for formulations aimed at improving nutrient absorption.


Researchers and industry professionals appreciate its safety profile and effectiveness, making Sodium L-ascorbate a preferred option over other antioxidants in many applications.
Sodium L-ascorbate has been used as a molecular tool for various biochemical applications.


Sodium L-ascorbate has also been used in a wide array of other chemical and immunological applications.
Applications of Sodium L-ascorbate: a molecular tool for various biochemical applications
In cosmetics and pharmaceutical formulations, Sodium L-ascorbate is valued for its stability and its ability to deliver vitamin C benefits—such as improved skin brightness, reduced oxidative stress, and enhanced collagen production—without the low pH that can irritate the skin.


In the human body, Sodium L-ascorbate provides vitamin C in a form that is readily absorbed and utilized. 
Like other forms of vitamin C, Sodium L-ascorbate plays essential roles in collagen synthesis, immune system support, neurotransmitter production, and protection against oxidative damage. 


Sodium L-ascorbate functions as a powerful reducing agent, neutralizing free radicals and regenerating other antioxidants such as vitamin E. 
Because of its neutral pH, Sodium L-ascorbate is frequently used in medical applications like intravenous vitamin C therapy, where high doses are required without increasing acidity in the bloodstream.


Beyond nutritional uses, Sodium L-ascorbate is widely employed as an additive in the food industry. 
Sodium L-ascorbate helps preserve color, flavor, and freshness in processed meats, beverages, and fruit products by preventing oxidation.
In meat processing, Sodium L-ascorbate  accelerates curing reactions and helps maintain the bright pink color of cured meats while reducing the formation of harmful nitrosamines. 


Sodium L-ascorbate also stabilizes food formulations by protecting sensitive ingredients from degradation caused by oxygen exposure.
Dietary supplement / Vitamin C source: Sodium L-ascorbate provides vitamin C in a buffered, less acidic form — useful for individuals or formulations where acidity may be a concern (e.g., stomach sensitivity).


Pharmaceutical / nutraceuticals: Sodium L-ascorbate is used in the manufacture of vitamin supplements, effervescent or chewable tablets, and formulations requiring vitamin C but with lower acidity / higher pH.
Biochemistry / laboratory reagent: Sodium L-ascorbate is used as a water-soluble vitamin C source / reducing agent / antioxidant in cell culture media, biochemical assays, research applications.


Because it dissolves well and yields neutral-to-mild pH solutions, Sodium L-ascorbate is often preferred over pure ascorbic acid for formulations where pH, solubility, or stability matter.
Sodium L-ascorbate is widely used across industries.
As a food additive, Sodium L-ascorbate has the E number E301 and is used as an antioxidant and an acidity regulator.


-Food additive / antioxidant / acidity regulator use of Sodium L-ascorbate:
As a sodium salt of vitamin C, Sodium L-ascorbate is used to prevent oxidation in foodstuffs, preserve color and flavor, delay spoilage.
In food-additive classification Sodium L-ascorbate is known as E301.


-Pharmaceutical Applications of Sodium L-ascorbate:
Sodium L-ascorbate is used as an antioxidant in pharmaceutical formulations, and also in food products where it increases the effectiveness of sodium nitrite against growth of Listeria monocytogenes in cooked meats.

Sodium L-ascorbate improves gel cohesiveness and sensory firmness of fiberized products regardless of vacuum treatment.
Sodium L-ascorbate is also used therapeutically as a source of vitamin C in tablets and parenteral preparations.

SOLUBILITY of SODIUM L-ASCORBATE:
Sodium L-ascorbate is soluble in water.
Sodium L-ascorbate is slightly soluble in alcohol.
Sodium L-ascorbate is insoluble in chloroform and ether.

NOTES of SODIUM L-ASCORBATE:
Sodium L-ascorbate is light sensitive.
Sodium L-ascorbate is incompatible with strong oxidizing agents and strong bases.

AIR & WATER REACTIONS of SODIUM L-ASCORBATE:
Sodium L-ascorbate is water soluble.
Aqueous solutions of Sodium L-ascorbate are subject to quick air oxidation at pH greater than 6.0.

REACTIVITY PROFILE of SODIUM L-ASCORBATE:
Sodium L-ascorbate is a weak base.
Materials in this group are generally soluble in water.
The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0.
They react as bases to neutralize acids.

These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

PRODUCTION METHODS of SODIUM L-ASCORBATE:
An equivalent amount of sodium bicarbonate is added to a solution of ascorbic acid in water.
Following the cessation of effervescence, the addition of propan-2-ol precipitates Sodium L-ascorbate.

BENEFITS & CHARACTERISTICS (COMPARED TO ASCORBIC ACID) of SODIUM L-ASCORBATE:
As a salt form, Sodium L-ascorbate is less acidic than ascorbic acid, which can make it gentler on the stomach when taken as a supplement.
Sodium L-ascorbate delivers vitamin C effectively, since upon dissolution it supplies the ascorbate anion (active form) to the body.

The improved water solubility and neutrality (pH) make Sodium L-ascorbate suitable for food fortification, beverages, tablets/capsules, and other formulations where acidity must be minimized.
As an antioxidant and reducing agent, Sodium L-ascorbate can help prevent oxidation in food products and in lab/industrial contexts — protecting vitamins, preventing discoloration or spoilage.

PRODUCTION of SODIUM L-ASCORBATE:
Sodium L-ascorbate is produced by dissolving ascorbic acid in water and adding an equimolar amount of sodium hydroxide or sodium bicarbonate in water.
After cessation of effervescence, the Sodium L-ascorbate is precipitated by the addition of isopropanol.

PHYSICAL and CHEMICAL PROPERTIES of SODIUM L-ASCORBATE:
molecular formula / molecular weight: c6h7nao6 = 198.11
physical state (20 deg.c): solid
storage temperature: room temperature (recommended in a cool and dark place, <15°c)
store under inert gas: store under inert gas
condition to avoid: air sensitive,hygroscopic
cas rn: 134-03-2
reaxys registry number: 5465157
pubchem substance id: 87562139
mdl number: mfcd00082340

name: sodium l-ascorbate (also simply “sodium ascorbate” when referring to the l-form)
iupac / systematic name: sodium (r)-2-((s)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
molecular formula: c₆h₇nao₆
molecular weight: ≈ 198.11 g/mol
cas number: 134-03-2
ec / einecs number: 205-126-1
form / appearance: white to slightly yellow crystalline powder or minute crystals.
optical activity (for l-form): [α]²⁰_d ≈ +103° to +106° (typical for “(+)-sodium l-ascorbate”)

cas: 134-03-2
iupac name: sodium 5-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-2,4-dioxooxolan-3-ide
molecular formula: c6h7nao6
inchi key: ifvcrspjfhgfcg-hxpaklqesa-n
smiles: [na+].occ@h
c1oc(=o)c-
c1=o
molecular weight (g/mol): 198.11

synonym: sodium ascorbate
appearance (color): white to pale cream or yellow
form: crystals or powder or crystalline powder
identification (ftir): conforms
optical rotation: +103° to +108° (c=5, water, 20°c)
solution test: 5% in water: clear colorless to pale yellow
assay from supplier's cofa: ≥98.5 to ≤101.5% (iodometric titration)
empirical formula (hill notation): c6h7nao6
cas number: 134-03-2
molecular weight: 198.11

beilstein: 3767246
ec number: 205-126-1
mdl number: mfcd00082340
unspsc code: 12352205
ecl@ss: 34058010
pubchem substance id: 24891261
nacres: na.79
cas: 134-03-2
molecular formula: c6h7nao6
molecular weight (g/mol): 198.11

mdl number: mfcd00082340
inchi key: ifvcrspjfhgfcg-hxpaklqesa-n
mdl number: mfcd00082340
inchi key: ifvcrspjfhgfcg-hxpaklqesa-n
iupac name: sodium 5-[(1s)-1,2-dihydroxyethyl]-3-hydroxy-2,4-dioxooxolan-3-ide
pubchem cid: 131674100
percent purity: ≥98.0% (t)
color: white
physical form: crystalline powder
molecular formula: c6h7nao6

smiles: [na+].occ@h
c1oc(=o)c-
c1=o
molecular weight (g/mol): 198.11
formula weight: 198.11
chemical name or material: sodium l-ascorbate
physical state: crystalline
color: light yellow
odor: odourless
melting point/freezing point: melting point/ range: 220 °c
initial boiling point and boiling range: no data available

flammability (solid, gas): may form combustible dust concentrations in air.
upper/lower flammability or explosive limits: no data available
flash point: no data available
autoignition temperature: no data available
decomposition temperature: 232 °c
ph: 7 - 8 at 100 g/l at 20 °c
viscosity: viscosity, kinematic: no data available
viscosity, dynamic: no data available
water solubility: 642,6 g/l at 20 °c - oecd test guideline 105- completely soluble

partition coefficient: n-octanol/water: log pow: < -4,2 at 22 °c - bioaccumulation is not expected.
vapor pressure: no data available
density: 1,88 g/cm3 at 19,7 °c - oecd test guideline 109
relative density: 1,88 at 19,7 °c - oecd test guideline 109
relative vapour density: no data available
particle characteristics: no data available
explosive properties: not classified as explosive.
oxidizing properties: none

other safety information: surface tension: 74 mn/m at 20,3 °c
melting point: 220 °c (dec.)(lit.)
alpha: 104 º (c=1, h2o 25 ºc)
boiling point: 235 °c
density: 1.66
vapor pressure: 0pa at 25℃
refractive index: 105.5 ° (c=10, h2o)
storage temp.: 2-8°c
solubility: h2o: 50 mg/ml

form: powder
color: white to slightly yellow
odor: odorless
ph: 7.48(1 mm solution);7.71(10 mm solution);7.64(100 mm solution);7.62(1000 mm solution)
biological source: synthetic (organic)
optical activity: [α]20/d +105±2°, c = 5% in h2o
water solubility: 620 g/l (20 ºc)
merck: 14,830
brn: 3767246

stability: stable. incompatible with strong oxidizing agents.
logp: -4.2 at 21.9℃
cas database reference: 134-03-2(cas database reference)
fda 21 cfr: 182.3731; 582.3731
substances added to food (formerly eafus): sodium ascorbate
scogs (select committee on gras substances): sodium l-ascorbate
ewg's food scores: 1
fda unii: s033eh8359
nci drug dictionary: cenolate
epa substance registry system: sodium ascorbate (134-03-2)

unspsc code: 85151701
nacres: na.79
molecular formula: c6h7nao6
molar mass: 198.11
density: 1.66
melting point: 220°c (dec.)(lit.)
boling point: 235 °c
specific rotation(α): 104 º (c=1, h2o 25 ºc)
flash point: 238.2°c
water solubility: 620 g/l (20 ºc)
solubility: soluble in water
vapor presure: 0pa at 25℃
appearance: white to yellow crystalline powder

color: white to slightly yellow
odor: odorless
merck: 14,830
brn: 3767246
ph: 7.48(1 mm solution);7.71(10 mm solution);7.64(100 mm solution);7.62(1000 mm solution)
storage condition: 2-8°c
stability: stable. incompatible with strong oxidizing agents.
sensitive: sensitive to light and humidity
refractive index: 105.5 ° (c=10, h2o)
mdl: mfcd00082340
physical and chemical properties: melting point 219-221°c
specific optical rotation: 104 ° (c = 1, h2o 25°c)
water-soluble: 620g/l (20°c)

Chemical formula: C6H7NaO6
Molar mass: 198.106 g•mol−1
Appearance: minute white to yellow crystals
Odor: odorless
Density: 1.66 g/cm3
Melting point: 218 °C (424 °F; 491 K) (decomposes)
Solubility in water: 62 g/100 mL (25 °C)
78 g/100 mL (75 °C)

Solubility: very slightly soluble in alcohol
insoluble in chloroform, ether
Physical state: crystalline
Color: light yellow
Odor: odorless
Melting point/freezing point:
Melting point/range: 220 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): May form combustible dust concentrations in air.

Viscosity 
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 642,6 g/l at 20 °C completely soluble
Partition coefficient: n-octanol/water:
log Pow: < -4,2 at 22 °C - Bioaccumulation is not expected.
Vapor pressure: No data available
Density: 1,88 g/cm3 at 19,7 °C

Relative density: 1,88 at 19,7 °C -
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 74 mN/m at 20,3 °C
Molecular Weight: 198.11 g/mol
Hydrogen Bond Donor Count: 3
Upper/lower flammability or explosive limits: No data available

Flash point: No data available 
Autoignition temperature: No data available
Decomposition temperature: 232 °C
pH: 7 - 8 at 100 g/l at 20 °C
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 2
Exact Mass: 198.01403222 g/mol
Monoisotopic Mass: 198.01403222 g/mol
Topological Polar Surface Area: 110Ų
Heavy Atom Count: 13
Formal Charge: 0

Complexity: 237
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Empirical Formula (Hill Notation): C 6 H 7 NaO 6
CAS Number: 134-03-2

Molecular Weight: 198.11
Beilstein: 3767246
EC Number: 205-126-1
MDL number: MFCD00082340
PubChem Substance ID: 329823275
CBNumber:CB8155737
Molecular Formula:C6H7NaO6
Molecular Weight:198.11
MDL Number:MFCD00082340
MOL File:134-03-2.mol

Melting point: 220 °C (dec.)(lit.)
alpha: 104 º (c=1, H2O 25 ºC)
Boiling point: 235 °C
Density: 1.66
vapor pressure: 0 Pa at 25℃
refractive index: 105.5 ° (C=10, H2O)
storage temp.: 2-8°C
solubility: H2O: 50 mg/mL
form: powder

color: white to slightly yellow
Odor: odorless
PH: 7.48(1 mM solution);7.71(10 mM solution);
7.64(100 mM solution);7.62(1000 mM solution)
optical activity: [α]20/D +105±2°, c = 5% in H2O
Water Solubility: 620 g/L (20 ºC)
Merck: 14,830
BRN: 3767246
Stability: Stable. 
Incompatible with strong oxidizing agents.

LogP: -4.2 at 21.9℃
CAS DataBase Reference: 134-03-2(CAS DataBase Reference)
FDA 21 CFR: 182.3731; 582.3731
Substances Added to Food (formerly EAFUS): SODIUM L-ASCORBATE
SCOGS (Select Committee on GRAS Substances): Sodium L-ascorbate
EWG's Food Scores: 1
FDA UNII: S033EH8359
EPA Substance Registry System: Sodium L-ascorbate (134-03-2)
Physical Appearance: A solid

Storage: Store at -20°C
M.Wt: 198.11
Cas No.: 134-03-2
Formula: C6H7NaO6
Solubility: ≥44.2 mg/mL in DMSO; 
≥2.82 mg/mL in EtOH with ultrasonic; 
insoluble in H2O
Chemical Name: sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
Canonical SMILES: O=C1C(O)=C([O-])[C@@H]([C@@H](O)CO)O1.[Na+]

Appearance: White to slightly yellow crystalline powder
Odor: Odorless
Melting Point: Approximately 220 °C (decomposes)
Solubility: Highly soluble in water (around 620 g/L at 20 °C); 
very slightly soluble in alcohol; insoluble in chloroform and ether.
pH: A 10% aqueous solution has a pH of 7.3-7.6, making it a neutral salt.
Molecular Formula: C₆H₇NaO₆
Molecular Weight: 198.11 g/mol

Stability: Stable under recommended storage conditions 
but incompatible with strong oxidizing agents, strong acids, and bases. 
Density: 1.66 - 1.88 g/cm³ (values vary slightly across sources)
Optical Activity: [α]²⁰/D +105±2° (c=5% in H₂O)
EC Number: 205-126-1
CAS Number: 134-03-2
Empirical Formula (Hill Notation): C6H7NaO6
CAS Number: 134-03-2

Molecular Weight: 198.11
Beilstein: 3767246
EC Number: 205-126-1
MDL number: MFCD00082340
UNSPSC Code: 85151701
PubChem Substance ID: 329748045
NACRES: NA.24
Physical state crystalline
Color: white

Odor: odorless
Melting point/freezing point:
Melting point: ca.232 °C - OECD Test Guideline 102
Initial boiling point and boiling range: No data available
Flammability (solid, gas): May form combustible dust concentrations in air.
Upper/lower flammability or explosive limits: No data available
Flash point No data available 
Autoignition temperature: No data available
Decomposition temperature: 232 °C
pH: 7 - 8 at 100 g/l at 20 °C

Viscosity 
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility 642,6 g/l at 20 °C - completely soluble
Partition coefficient: n-octanol/water
log Pow: < -4,2 at 22 °C - Bioaccumulation is not expected.
Vapor pressure No data available
Density 1,88 g/cm3 at 19,7 °C
Relative density: 1,88 at 19,7 °C

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 74 mN/m at 20,3 °C
Appearance: White to slightly yellow crystalline powder
Identification: Positive
Specific Optical Rotation: +103°-+106°
Clarity Of Solution: Clear

PH(10%,W/V): 7.0-8.0
Loss On Drying: ≤0.25%
Molecular Formula (Sodium L-ascorbate): C4H7NaO 6
Molecular Weight: 198.11 g/mol
Chemical Name: Sodium L-ascorbate
CAS Number: 134-03-2
Form: Solid
Color: white or almost white

Odor: odorless
pH value: 7.0 ~ 8.0
Characteristics: White or very faintly yellow crystals or crystalline powder
Identification: IR: Complied
Identification: Positive
Identification: NA: Positive
Assay: 99.0% ~ 101.0%
Loss on drying: ≤ 0.25%

Appearance of solution: Clear and ≤Y6 , BY6
Specific Rotation: +103º ~ +106º
Alkalinity (pH): 7.0 ~ 8.0
Oxalic Acid (Impurity E): ≤ 0.3%
Related substances: Imputiry C, D: ≤ 0.15%
Related substances: Unspecified Impurities: ≤ 0.10%
Related substances: Total Impurities other than C, D: ≤ 0.2%

Residual Solvents: Methanol ≤ 3000 ppm
Lead: ≤ 2 ppm
Arsenic: ≤ 3 ppm
Mercury: ≤ 1 ppm
Sulphates: ≤ 0.0150%
Copper: ≤ 5 ppm
Iron: ≤ 2 ppm
Nickel: ≤ 1 ppm
Heavy metals: ≤ 0.0010%

IUPAC Name: Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate
Molecular Formula: C₆H₇NaO₆
Molecular Weight: 198.11 g/mol
CAS Number: 134-03-2
EC Number (EINECS): 205-126-1
PubChem CID: 23667548
ChemSpider ID: 16736174
Chemical Name: Sodium L-ascorbate

IUPAC Name: Sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-oxo-2H-furan-5-olate
CAS Number: 134-03-2
EC Number: 205-126-1
Molecular Formula: C₆H₇NaO₆
Molecular Weight: 198.11 g/mol
Structure: A white to off-white crystalline powder
Appearance: White to off-white crystalline powder
Solubility in Water: Highly soluble (620 g/L at 20 °C)

LogP (Partition Coefficient): −4.2 at 21.9 °C
Stability: Stable under recommended storage conditions; 
incompatible with strong oxidizing agents
Melting Point: Decomposes before melting
pH (10% solution): Approximately 7.0–8.0
Density: Approximately 1.66 g/cm³
Appearance: White to light yellow crystalline powder
Odor: Odorless

pH (10% solution): 7.0–8.0
Melting Point: Approximately 218–220 °C (decomposes)
Boiling Point: Approximately 552.7 °C at 760 mmHg
Density: 1.66–1.88 g/cm³
Water Solubility: 620–642.6 g/L at 20–25 °C
Solubility in Alcohol: Very slightly soluble
Solubility in Chloroform and Ether: Insoluble
Partition Coefficient (log P): < –4.2 at 22 °C (indicates low potential for bioaccumulation)

Name: Sodium L-ascorbate — the sodium salt of Ascorbic acid (Vitamin C). 
IUPAC / systematic name: sodium (R)-2-((S)-1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate 
Molecular formula: C₆H₇NaO₆ 
Molecular weight: ~ 198.11 g/mol 
CAS number: 134-03-2 
EC / EINECS number: 205-126-1 
Form / Appearance: usually a white to slightly yellow crystalline powder. 
Solubility: Highly soluble in water. According to ChemicalBook: ~ 620 g/L at 20 °C. 
pH in solution: A 10% aqueous solution typically has pH ~ 7.4–7.7; more generally pH tends to be around neutral to slightly alkaline in solution.

Melting / Decomposition point: decomposes around 220 °C (some sources list 219–221 °C). 
Boiling point / thermal behavior: reported “boiling point” around 235 °C (though in practice decomposition often precedes true boiling) according to some supplier data. 
Density / Relative density: reported around 1.66 g/cm³ (bulk/powder) in some sources. 
Optical activity / Chirality: Sodium L-ascorbate retains chirality; for example, specific rotation is reported around +103° to +106° (for L-form). 
Stability / Reactivity: Sodium L-ascorbate is water-soluble, stable under typical storage conditions (dry, cool, sealed), but aqueous solutions — especially at pH > ~6 — are subject to oxidation by atmospheric oxygen or oxidizing agents. 
Reactivity: As the sodium salt of ascorbic acid, it acts as a reducing agent / antioxidant under appropriate conditions.

FIRST AID MEASURES of SODIUM L-ASCORBATE:
-Description of first-aid measures:
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Make victim drink water (two glasses at most). 
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of SODIUM L-ASCORBATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of SODIUM L-ASCORBATE:
-Extinguishing media:
*Suitable extinguishing media:
Water 
Foam 
Carbon dioxide (CO2) 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet. 
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM L-ASCORBATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection:
Recommended Filter type: Filter type P1
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SODIUM L-ASCORBATE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing. 
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.
Light sensitive.

STABILITY and REACTIVITY of SODIUM L-ASCORBATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
no information available
-Incompatible materials:
No data available


 

 
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