Sodium Lactate 60 % (CAS 72-17-3 for DL-racemic or unspecified stereochemistry and CAS 867-56-1 for natural L-(+)-stereoisomer, EC 200-772-0 / 212-762-3), globally recognized across food, cosmetic, and pharmacopeial standards as Lactic Acid Sodium Salt Solution, Sodium 2-Hydroxypropanoate 60%, Food Additive E325, and Natrii Lactatis Solutio, is a crystal-clear, concentrated 60% w/w aqueous solution of the monosodium salt of alpha-hydroxypropionic acid. Also traded across international chemical procurement channels as Monosodium Lactate 60% Liquid, Sodium Alpha-Hydroxypropionate Solution, Sodium L-Lactate 60%, INS 325, and Sodyum Laktat %60, this odorless, non-toxic, hygroscopic liquid raw material is supplied by Ataman Kimya in Food Grade (FCC / E325), Cosmetic Grade (INCI: SODIUM LACTATE), Pharmaceutical Grade (USP / EP / BP), and Technical Grade specifications.
Across the global food and meat-processing industries, E325 Sodium Lactate 60% is extensively utilized in cooked sausages, frankfurters, salami, sucuk, hams, smoked meats, poultry, seafood, bakery doughs, and ready-to-eat meals to depress water activity (aw), extend refrigerated shelf life, suppress pathogenic Listeria monocytogenes and Clostridium botulinum growth, enhance cooking yield and sliceability, and impart a mild savory flavor profile. In personal care, dermatological, pharmaceutical, and industrial sectors, INCI-grade Sodium Lactate 60 % functions as a biomimetic Natural Moisturizing Factor (NMF) humectant that increases stratum corneum hydration by up to 84%, a pH-buffering alpha-hydroxy acid co-active, a bar-hardening and mold-release additive in cold-process and hot-process soap making, a metabolic bicarbonate precursor in USP/EP intravenous Hartmann's/Ringer's lactate and peritoneal dialysis solutions, and a biodegradable humectant and pH control agent in leather tanning, textile finishing, fermentation bioprocessing, and eco-friendly deicing fluids.
From a chemical and molecular perspective, the active solute in Sodium Lactate 60 % Solution possesses the empirical molecular formula C3H5NaO3 and the condensed structural formula CH3-CH(OH)-COONa (anhydrous molecular weight 112.06 g/mol, formulated at 60.0% w/w active salt dissolved in 40.0% w/w purified water H2O), consisting of a three-carbon propanoate backbone bearing a chiral secondary hydroxyl group (-OH) at the alpha (C-2) carbon and a resonance-stabilized carboxylate anion (-COO-) ionically coordinated with a sodium cation (Na+). This compact alpha-hydroxy carboxylate architecture features one hydrogen-bond donor (-OH), three hydrogen-bond acceptors, and a densely hydrated Na+ counterion that collectively bind water molecules via strong ion-dipole and hydrogen-bonding networks, imparting a high liquid density of 1.310 to 1.340 g/cm3 at 20 °C, a pumpable Newtonian viscosity of 60 to 110 mPa.s, a neutral aqueous pH of 6.5 to 7.5 (conjugate lactic acid pKa = 3.86), and an equilibrium water activity (aw) of 0.78 to 0.81.
Formulators and plant engineers overwhelmingly prefer liquid Sodium Lactate 60 % over anhydrous crystalline sodium lactate powder (96%–98% solid) because dry Monosodium Lactate is fiercely deliquescent—absorbing atmospheric moisture within minutes of bag opening to form sticky, unpumpable cakes—whereas the 60% w/w aqueous solution is a pre-dissolved, non-dusting, meterable liquid that blends instantaneously into cold meat brines, cosmetic emulsions, and soap lye solutions without exothermic dissolution heat. Compared to traditional polyols and preservatives such as glycerin, propylene glycol, sodium chloride, and sodium benzoate, Lactic Acid Sodium Salt 60% delivers nearly twice the moisture-binding capacity of glycerin in stratum corneum keratin without tacky skin drag, lowers water activity and inhibits Listeria monocytogenes in neutral-pH meat matrices (pH 5.8 to 6.6) where benzoates and sorbates are inactive, avoids the corrosive acidity (pH < 2.0) and protein-denaturing shock of unneutralized 80%–88% lactic acid, and costs significantly less than potassium lactate while providing clean savory flavor enhancement.
CAS Number: 72-17-3 (Sodium Lactate / Sodium DL-Lactate, Unspecified or Racemic Stereochemistry); 867-56-1 (Sodium L-(+)-Lactate / Sodium (S)-2-Hydroxypropanoate, Natural Bio-Fermentation Isomer); 312-85-6 (Sodium D-(-)-Lactate)
EC Number: 200-772-0 (CAS 72-17-3); 212-762-3 (CAS 867-56-1); 206-231-5 (CAS 312-85-6)
Molecular Formula: C3H5NaO3 (Condensed Structural Formula: CH3-CH(OH)-COONa or NaC3H5O3; supplied commercially as a 60.0% w/w aqueous solution in 40.0% w/w purified water H2O)
Molecular Weight: 112.06 g/mol (112.060 g/mol for anhydrous C3H5NaO3; effective stoichiometric solution equivalent weight for 60.0% w/w active liquid is 186.77 g of solution per 1.000 mole of Sodium Lactate)
INCI Name: SODIUM LACTATE (or SODIUM LACTATE (and) AQUA / WATER for the 60% w/w solution)
E Number: E325 (INS 325 / Food Additive E 325)
Melting Point: -15 °C to +17 °C crystallization / solidification onset for the 60% w/w aqueous syrup solution depending on stereochemical purity and subcooling (60% w/w DL-racemic solution remains a supercooled viscous liquid down to -12 °C to -20 °C, whereas 60% w/w stereochemically pure L-(+)-solution exhibits a thermodynamic saturation/crystallization point near +10 °C to +17 °C; pure anhydrous crystalline C3H5NaO3 melts at 161 °C to 165 °C and decomposes above 220 °C)
Boiling Point: 112 °C to 115 °C at 101.3 kPa (113 °C / 235 °F standard boiling point for 60% w/w aqueous syrup solution at 760 mmHg; 109 °C for 50% w/w solution; anhydrous ionic solid decomposes thermally above 200 °C to 240 °C without a reversible boiling transition)
Viscosity: 60 to 110 mPa.s (cP) at 20 °C to 25 °C for commercial 60.0% w/w aqueous solution (typically 75 to 98 mPa.s at 20 °C and 55 to 75 mPa.s at 25 °C; decreases to 20 to 30 mPa.s at 50 °C and rises to 180 to 320 mPa.s at 5 °C; 50% w/w solution viscosity is 18 to 28 mPa.s at 25 °C)
Density: 1.310 to 1.340 g/cm3 (1,310 to 1,340 kg/m3) at 20 °C for commercial 60.0% w/w aqueous solution (compendial specification range: 1.31 to 1.33 g/mL at 20 °C, corresponding to 34.5 to 36.8 degrees Baume; 50.0% w/w solution density is 1.255 to 1.275 g/cm3 at 20 °C; true crystal density of anhydrous solid C3H5NaO3 is 1.33 to 1.38 g/cm3)
Most Frequently Encountered Synonyms:
Sodium Lactate 60 %
Sodium Lactate 60%
Sodium Lactate 60% Solution
Sodium Lactate 60% w/w Aqueous Solution
Sodium Lactate 60% Liquid
Sodium Lactate Solution (60%)
Sodium L-Lactate 60% Solution
Sodium L-(+)-Lactate 60%
Sodium (S)-Lactate 60% Solution
Sodium DL-Lactate 60% Solution
Sodium (2S)-2-Hydroxypropanoate 60% Solution
Sodium (2RS)-2-Hydroxypropanoate 60% Solution
PRODUCT IDENTIFICATION, CHEMICAL NOMENCLATURE AND STEREOCHEMICAL ARCHITECTURE
Sodium Lactate 60 % (CAS 72-17-3 for the racemic or unspecified stereochemistry registry and CAS 867-56-1 for the stereochemically pure L-(+)-isomer; EC / EINECS 200-772-0 and 212-762-3) is the standardized 60.0% w/w concentrated aqueous liquid solution of the monosodium salt of lactic acid (2-hydroxypropanoic acid), representing one of the most technically versatile bio-based humectants, water-activity depressants, bacteriostatic shelf-life extenders, pH buffers, and physiological electrolyte raw materials in global chemical commerce. In international chemical inventories, food additive legislation, and pharmacopeial compendia, this product is systematically indexed under the IUPAC names Sodium 2-hydroxypropanoate (or Sodium (2S)-2-hydroxypropanoate for the natural L-isomer) and the Chemical Abstracts Service name Propanoic acid, 2-hydroxy-, monosodium salt. Across commercial procurement catalogs, meat-processing plants, cosmetic formulation laboratories, and soap-making operations, buyers routinely specify the material under its established synonyms: Lactic Acid Sodium Salt 60%, Monosodium Lactate Solution, Sodium Alpha-Hydroxypropionate 60%, E325 Sodium Lactate, Humectant E325, INS 325, Natrii Lactatis Solutio, and in Turkish chemical trade, Sodyum Laktat %60, Sıvı Sodyum Laktat, or Laktik Asit Sodyum Tuzu.
To understand the exceptional water-binding power, bacteriostatic mechanism, and phase behavior of Sodium Lactate 60 %, formulators and quality-control engineers must examine its molecular structure, stereochemistry, and stoichiometric solution architecture:
Molecular Architecture of the Alpha-Hydroxy Carboxylate Core (C3H5NaO3, MW 112.06 g/mol):
Each formula unit of active Sodium Lactate consists of a compact three-carbon propanoate skeleton (CH3-CH(OH)-COONa) containing three distinct functional regions: (a) a terminal hydrophobic methyl group (-CH3 at C-3); (b) a central sp3-hybridized chiral alpha-carbon (C-2) bearing a polar secondary hydroxyl group (-OH) that acts simultaneously as a hydrogen-bond donor and acceptor; and (c) a terminal sp2-hybridized carboxylate anion (-COO- at C-1) balanced electrostatically by a sodium cation (Na+). With a topological polar surface area of 60.4 Square Angstroms, 1 hydrogen-bond donor, and 3 hydrogen-bond acceptors packed into a low molecular weight of just 112.06 g/mol, Monosodium Lactate possesses one of the highest charge-to-mass and hydrogen-bonding-to-mass densities of any organic salt. When dissolved at 60.0% w/w in 40.0% w/w purified water (corresponding to 1.50 grams of dry Sodium Lactate per 1.00 gram of water, or a molar ratio of approximately 1.00 mole of C3H5NaO3 to 4.15 moles of H2O), virtually every water molecule in the solution is coordinated within the primary or secondary hydration shells of the Na+ cations, -COO- oxygens, and alpha-OH groups!
Stereochemical Distinction: Natural L-(+)-Sodium Lactate (CAS 867-56-1) vs. Racemic DL-Sodium Lactate (CAS 72-17-3):
Because the alpha-carbon (C-2) of lactic acid is bonded to four different substituents (-H, -OH, -CH3, and -COO-), Sodium Lactate is a chiral molecule that exists in two enantiomeric configurations:
- Sodium L-(+)-Lactate (also designated Sodium (S)-(+)-2-hydroxypropanoate, CAS 867-56-1, EC 212-762-3): This is the physiological, biologically natural stereoisomer produced by selective microbial fermentation of plant sugars (corn dextrose, beet sucrose, cane molasses, or tapioca starch) and formed endogenously in human muscle, blood, and skin stratum corneum. Note on Optical Rotation Inversion: While free L-(+)-lactic acid in water is dextrorotatory (+), converting L-(+)-lactic acid into its ionized sodium salt (Sodium L-Lactate) inverts the sign of plane-polarized light rotation to levorotatory: compendial Sodium (S)-Lactate Solution exhibits a specific optical rotation ([alpha]D20) of -11.5 to -14.5 degrees (calculated on the dry substance)! In human parenteral medicine (USP / Ph. Eur. Natrii S-lactatis solutio), infant nutrition, and premium clean-label meat and cosmetic applications, stereochemically pure L-(+)-Sodium Lactate (>= 95% to 98% L-enantiomer) is preferred because human hepatic L-lactate dehydrogenase (L-LDH) metabolizes L-lactate rapidly and completely into pyruvate and bicarbonate.
- Sodium DL-Lactate (also designated Sodium (2RS)-2-hydroxypropanoate, CAS 72-17-3, EC 200-772-0): This is the optically inactive ([alpha]D20 = -0.5 to +0.5 degrees) 50:50 racemic mixture of L-(+)- and D-(-)-isomers, or the general umbrella CAS registry number used across chemical inventories when stereochemistry is unspecified. Both L- and DL-grades of E325 Sodium Lactate 60% exhibit identical chemical humectancy, water-activity depression, soap-hardening performance, and pH buffering.
Exact Stoichiometric Conversion Factors for Formulators (60% w/w Solution vs. Anhydrous Salt vs. Free Lactic Acid):
In commercial formulation calculations, buyers must convert accurately between 60.0% w/w Sodium Lactate Solution (density ~1.325 g/cm3 at 20 °C), 100% Anhydrous Sodium Lactate (C3H5NaO3, MW = 112.06 g/mol), and 100% Free Lactic Acid (C3H6O3, MW = 90.08 g/mol) or commercial 80% / 88% w/w Lactic Acid:
- 1.000 kg of Sodium Lactate 60 % Solution contains 0.600 kg (600 g) of anhydrous Sodium Lactate (C3H5NaO3) and 0.400 kg (400 g) of purified water, and is stoichiometrically equivalent to 0.4823 kg (482.3 g) of 100% pure Lactic Acid (since 90.08 / 112.06 x 0.600 = 0.4823), or 0.6029 kg of commercial 80% w/w Lactic Acid (or 0.5481 kg of 88% w/w Lactic Acid).
- Conversely, to deliver 1.000 kg of anhydrous Sodium Lactate active into a meat brine, cosmetic batch, or soap recipe, a formulator must weigh 1.6667 kg (or measure 1.258 Liters at 1.325 kg/L density) of Sodium Lactate 60 % Solution while subtracting 0.6667 kg of water from the batch water charge.
- On a volumetric basis at 20 °C (specific gravity 1.325 g/mL): 1.000 Liter of Sodium Lactate 60 % Solution weighs 1,325 grams and delivers 795.0 grams of anhydrous Sodium Lactate (equivalent to 639.0 grams of 100% Lactic Acid) and 530.0 grams of water.
Clarification on Dairy-Free / Lactose-Free Origin:
Despite the phonetic similarity between the words "lactate" and "lactose" (milk sugar, C12H22O11), Sodium Lactate 60 % is a simple 3-carbon organic acid salt manufactured by fermenting plant-derived carbohydrate sugars (corn, sugar beet, sugar cane, or tapioca) and contains 0.00% lactose, 0.00% casein or whey milk proteins, and zero dairy allergens. It is 100% safe for lactose-intolerant consumers, milk-allergic individuals, and certified Vegan, Halal, and Kosher Parve formulations.
PHYSICAL AND CHEMICAL PROPERTIES (NUMERICAL DATA AND ANALYTICAL SPECIFICATIONS)
To support precision quality control, meat-brine water-activity modeling, cosmetic NMF formulation, and pharmacopeial verification, the following quantitative physical, chemical, thermodynamic, rheological, and purity parameters define commercial Sodium Lactate 60 % (CAS 72-17-3 / CAS 867-56-1, EC 200-772-0 / 212-762-3, E325) supplied by Ataman Kimya:
1. Molecular, Structural, and Stoichiometric Constants:
Chemical Name: Sodium Lactate 60 % Aqueous Solution / Sodium 2-Hydroxypropanoate 60% Solution / Lactic Acid Monosodium Salt 60% Solution
CAS Registry Numbers: 72-17-3 (DL- / Unspecified Stereochemistry); 867-56-1 (L-(+)-Stereoisomer); 312-85-6 (D-(-)-Stereoisomer)
EC / EINECS Numbers: 200-772-0 (CAS 72-17-3); 212-762-3 (CAS 867-56-1); 206-231-5 (CAS 312-85-6)
E Number / INS Number: E325 / INS 325
INCI Monograph Name: SODIUM LACTATE (and) AQUA / WATER
FDA UNII Codes: TU7HW0W0QT (Sodium DL-Lactate); Y592956Z2P (Sodium L-Lactate)
Empirical Formula of Active Solute: C3H5NaO3 (NaC3H5O3)
Condensed Structural Formula: CH3-CH(OH)-COONa
SMILES Notation: Na+ . C C(O) C(=O) O-
InChIKey: JGSARLDLIJGVTE-UHFFFAOYSA-M (Racemic / Unspecified); JGSARLDLIJGVTE-REOHCLBHSA-M (L-Isomer)
Molecular Weight of Anhydrous Solute: 112.060 g/mol (standard specification value: 112.06 g/mol; Monoisotopic Exact Mass: 112.01364 g/mol)
Effective Stoichiometric Equivalent Weight of 60.0% w/w Solution: 186.77 g of 60% solution per 1.000 mol of C3H5NaO3
Theoretical Elemental Composition of Anhydrous C3H5NaO3: Carbon (C) 32.15% w/w; Hydrogen (H) 4.50% w/w; Oxygen (O) 42.83% w/w; Sodium (Na) 20.52% w/w
Theoretical Elemental Composition of 60.0% w/w Aqueous Solution (60% C3H5NaO3 + 40% H2O): Carbon (C) 19.29% w/w; Hydrogen (H) 7.17% w/w; Oxygen (O) 61.23% w/w; Sodium (Na) 12.31% w/w (delivering 123.1 g of elemental Na+ per kg of 60% solution, compared to 393.4 g Na+ per kg of NaCl table salt)
Lactic Acid Equivalence Factor: 1.0000 g anhydrous Sodium Lactate = 0.80385 g pure Lactic Acid (C3H6O3, MW 90.08 g/mol); 1.0000 g of Sodium Lactate 60 % Solution = 0.4823 g pure Lactic Acid
Physical State, Color, Odor, and Organoleptic Profile:
Appearance at 20 °C and 101.3 kPa: Clear, colorless to very faintly straw-tinted, syrupy, slightly viscous hygroscopic liquid completely free of suspended particulates or turbidity
Color Index (APHA / Hazen Pt-Co Scale per ISO 6271 / ASTM D1209): Maximum 30 to 50 APHA for Food / FCC / E325 Grade; Maximum 15 to 25 APHA (water-white) for Cosmetic (INCI) and Pharmaceutical (USP / Ph. Eur.) Grades; up to 50 to 100 APHA for Technical Grade
Odor Profile: Practically odorless, or possessing an extremely faint, clean, mild characteristic note (100% free of acrid volatile acetic, butyric, or propionic off-odors)
Taste Profile (in dilute aqueous food matrices): Mildly saline, clean, rounded savory umami-like taste (possessing approximately 45% to 50% of the perceived saltiness of sodium chloride NaCl while containing 68.7% less elemental sodium per gram than NaCl on a 60% solution basis!)
Thermal Transitions, Crystallization Point, Melting Point, and Boiling Point:
Melting Point of Anhydrous Solid C3H5NaO3: 161 °C to 165 °C (322 °F to 329 °F; decomposes thermally above 200 °C to 240 °C without boiling)
Crystallization / Solidification Point of 60.0% w/w Aqueous Solution:
- For 60% w/w Sodium L-(+)-Lactate (High Enantiomeric Purity): Thermodynamic saturation/crystallization temperature is approximately +10 °C to +17 °C; due to high viscosity and strong hydration-shell supercooling, the liquid typically remains clear down to 0 °C to +5 °C before slowly nucleating white needle-like crystals of hydrated/anhydrous Sodium L-Lactate (which redissolve completely upon gentle warming to 25 °C to 35 °C)
- For 60% w/w Sodium DL-Lactate (Racemic Mixture): Eutectic suppression between D- and L-enantiomers depresses the freezing/glass-transition point down to -12 °C to -25 °C
Boiling Point at 101.3 kPa (760 mmHg):
- 50.0% w/w Aqueous Solution: 108.5 °C to 109.5 °C
- 60.0% w/w Commercial Solution: 112.0 °C to 115.0 °C (standard reference value: 113.0 °C / 235.4 °F / 386.15 K)
- 70.0% w/w Concentrated Syrup: 118.0 °C to 121.0 °C
Flash Point (Closed Cup / Open Cup): Not Applicable for aqueous 60% solution (non-flammable water-based electrolyte solution; does not flash prior to water evaporation at 113 °C; anhydrous dry residue chars/flashes only above 180 °C to 220 °C)
Vapor Pressure at 20 °C: Approximately 18.0 to 19.2 hPa (mbar) for the 60% w/w aqueous solution (governed exclusively by the equilibrium water vapor pressure above a 0.78–0.80 aw solution; the ionic C3H5NaO3 solute itself has zero vapor pressure, < 10^-7 Pa)
Density, Specific Gravity, Refractive Index, and Concentration Table (at 20 °C):
True Crystal Density of Anhydrous Solid C3H5NaO3: 1.330 to 1.380 g/cm3 at 20 °C
Density / Specific Gravity of Aqueous Sodium Lactate Solutions at 20 °C (d20/4) and Refractive Index (nD20):
- 10.0% w/w Aqueous Solution: Density = 1.052 g/cm3; Refractive Index nD20 = 1.3475
- 20.0% w/w Aqueous Solution: Density = 1.106 g/cm3; Refractive Index nD20 = 1.3625
- 30.0% w/w Aqueous Solution: Density = 1.161 g/cm3; Refractive Index nD20 = 1.3778
- 40.0% w/w Aqueous Solution: Density = 1.216 g/cm3; Refractive Index nD20 = 1.3932
- 50.0% w/w Commercial Solution: Density = 1.265 to 1.272 g/cm3 (30.5 to 31.2 Baume); Refractive Index nD20 = 1.4085 to 1.4110
- 60.0% w/w Standard Commercial Solution: Density = 1.310 to 1.340 g/cm3 (typical batch value: 1.320 to 1.332 g/cm3, or 35.2 to 36.2 degrees Baume); Refractive Index nD20 = 1.4220 to 1.4260 (typical: 1.4235 at 20 °C)
Rheology, Dynamic Viscosity, Water Activity (aw), and Osmolality:
Dynamic Viscosity of Sodium Lactate 60 % Solution as a Function of Temperature (Brookfield LV / Capillary Viscometry):
- At 5 °C: 180 to 310 mPa.s (cP)
- At 15 °C: 95 to 140 mPa.s (cP)
- At 20 °C: 75 to 110 mPa.s (cP)
- At 25 °C: 55 to 80 mPa.s (cP)
- At 40 °C: 28 to 42 mPa.s (cP)
- At 60 °C: 14 to 22 mPa.s (cP)
(By comparison, 50% w/w Sodium Lactate solution exhibits a viscosity of only 18 to 28 mPa.s at 25 °C, whereas 70% w/w supersaturated syrup exceeds 350 to 500 mPa.s)
Equilibrium Water Activity (aw) of Neat 60.0% w/w Solution at 25 °C: aw = 0.78 to 0.81 (corresponding to an Equilibrium Relative Humidity ERH of 78% to 81%—meaning Sodium Lactate 60% is intrinsically self-preserving against bacteria and absorbs moisture from air above 80% RH while retaining bound water below 75% RH!)
Water Activity (aw) Depression in Aqueous / Meat Matrices at 25 °C:
- 1.0% w/w Anhydrous Sodium Lactate (1.67% w/w of 60% solution): lowers water activity aw from 1.000 to ~0.9945
- 2.0% w/w Anhydrous Sodium Lactate (3.33% w/w of 60% solution): lowers water activity aw to ~0.9885
- 3.0% w/w Anhydrous Sodium Lactate (5.00% w/w of 60% solution): lowers water activity aw to ~0.9820
- 4.8% w/w Anhydrous Sodium Lactate (8.00% w/w of 60% solution): lowers water activity aw to ~0.9700
Molarity and Osmolarity of 60.0% w/w Solution (at Density 1.325 g/mL):
- Molar Concentration: 7.094 mol/L (7,094 mmol/L of C3H5NaO3)
- Theoretical Osmolarity: 14.19 Osmol/L (14,188 mOsmol/L; 1.0 mL of 60% solution contains 7.09 mmol of Na+ and 7.09 mmol of Lactate-)
Solubility, pH, Buffering Capacity, and Partitioning:
Solubility of Anhydrous Sodium Lactate in Water at 20 °C to 25 °C: > 1,500 g/L (> 1.5 g per mL of water, corresponding to > 60% w/w miscibility)
Solubility in Ethanol (95% v/v at 20 °C): Freely soluble / miscible (dissolves up to 100 to 300 g/L in 95% ethanol, unlike most inorganic sodium salts which precipitate in alcohol)
Solubility in Glycerin and Propylene Glycol: Completely miscible in all proportions
Solubility in Nonpolar Organic Solvents (Diethyl Ether, Acetone, Chloroform, Hexane, Vegetable Oils, Mineral Oils): Practically insoluble (< 0.1 g/L)
Acid Dissociation Constant (pKa of Conjugate Lactic Acid at 25 °C): pKa = 3.86 (Ka = 1.38 x 10^-4 mol/L), providing maximum Henderson-Hasselbalch buffering capacity across pH 2.86 to 4.86 and stable neutral pH control at pH 5.5 to 7.5
pH of Commercial 60.0% w/w Solution (Direct or Diluted 1:5 / 10%–20% w/w in CO2-Free Water at 20 °C to 25 °C):
- Food / FCC / E325 / Cosmetic Grade Specification: pH 6.5 to 7.5 (broad compendial range: 5.0 to 9.0 or 6.0 to 8.5 depending on monograph; Ataman Kimya neutral grades are tightly buffered at pH 6.5 to 7.5)
Octanol-Water Partition Coefficient (log Pow at 20 °C): -3.06 to -3.60 (extremely hydrophilic, zero bioaccumulation)
Compendial Assay, Stereochemical Purity, and Trace Impurity Limits (FCC / E325 EU Reg. 231/2012 / USP-NF / Ph. Eur. Monographs 2115 & 2116):
Assay (Active Sodium Lactate Content by Non-Aqueous Perchloric Acid / Cation-Exchange Titration or HPLC):
- Standard Commercial 60% Grade: 58.8% to 61.2% w/w C3H5NaO3 (59.0% to 61.0% w/w; nominal 60.0% w/w, equivalent to 98.0% to 102.0% of labeled concentration per FCC/USP)
- Ph. Eur. Monograph (Natrii lactatis solutio / Natrii S-lactatis solutio): >= 50.0% w/w C3H5NaO3 (and 96.0% to 104.0% of the nominal labeled concentration, standardly supplied at 60.0% w/w)
Enantiomeric Purity (Chiral HPLC or Enzymatic L-LDH Assay for L-(+)-Grade): >= 95.0% to 98.5% L-(+)-isomer (<= 2.0% to 5.0% D-isomer)
Specific Optical Rotation ([alpha]D20, calculated on anhydrous basis for L-(+)-Grade): -11.5 to -14.5 degrees
Acidity or Alkalinity (USP / Ph. Eur. / FCC Titration against Phenolphthalein): Not more than 0.5 mL of 0.1 M HCl or 0.1 M NaOH required per 10 g of solution to neutralize free acid or free alkali
Chloride (Cl-): Maximum 0.005% to 0.05% w/w (50 ppm max for Ph. Eur./USP Pharma Grade; 500 ppm max for Technical/Food Grade; typical < 20 ppm)
Sulfate (SO4^2-): Maximum 0.005% to 0.02% w/w (50 to 200 ppm; typical < 20 ppm)
Citrate, Oxalate, Phosphate, or Tartrate (FCC / EU E325 / USP Limit Test): Passes test (No turbidity with calcium chloride or silver nitrate)
Reducing Sugars / Residual Carbohydrates (Fehling's / Benedict's Copper Reduction Test): Passes test (No red cuprous oxide precipitate; < 0.05% residual unfermented sugars, preventing Maillard browning during meat cooking or cosmetic heating!)
Methanol and Methyl Esters (GC Headspace per FCC / EU E325): Maximum 50 to 250 mg/kg (typical Not Detected < 10 ppm)
Volatile Fatty Acids (Acetic, Propionic, Butyric Acids): Passes compendial odor test upon acidification with H2SO4 at 50 °C (Zero volatile fatty acid off-odor)
Cyanide (CN-): Maximum 0.5 to 1.0 mg/kg (confirming 100% fermentation origin rather than petrochemical lactonitrile synthesis)
Iron (Fe): Maximum 5.0 to 10.0 mg/kg (ppm; typical < 1.0 ppm)
Calcium (Ca2+) and Magnesium (Mg2+): Maximum 10 to 20 mg/kg (ppm)
Heavy Metals (Total as Pb): Maximum 5.0 to 10.0 mg/kg (ppm)
Lead (Pb, ICP-MS / AAS per EU Reg. 231/2012 & FCC): Maximum 2.0 mg/kg (2.0 ppm; typical < 0.1 ppm)
Arsenic (As, ICP-MS): Maximum 1.0 to 3.0 mg/kg (ppm; typical < 0.1 ppm)
Mercury (Hg, Cold-Vapor AAS): Maximum 1.0 mg/kg (1.0 ppm; typical < 0.02 ppm)
INDUSTRIAL MANUFACTURING PROCESS: CARBOHYDRATE BIO-FERMENTATION AND PRECISION NEUTRALIZATION
Commercial Food Grade (E325 / FCC), Cosmetic Grade (INCI: SODIUM LACTATE), and Pharmaceutical Grade (USP / Ph. Eur.) Sodium Lactate 60 % is manufactured globally via a clean, dairy-free, non-GMO biotechnological fermentation and neutralization process starting from renewable plant carbohydrates:
Stage 1: Homofermentative Lactic Acid Bio-Fermentation of Plant Sugars:
Refined plant-derived D-glucose (dextrose hydrolyzed from corn or tapioca starch) or sucrose (from sugar beet or sugar cane) is dissolved in demineralized water (120 to 180 g/L sugar) with trace yeast extract and mineral nutrients, heat-sterilized, and fed into closed 100-to-250 m3 316L stainless-steel anaerobic/microaerophilic bioreactors. The medium is inoculated with pure, non-pathogenic homofermentative lactic acid bacteria (such as Lactobacillus delbrueckii, Lacticaseibacillus paracasei, Lactiplantibacillus plantarum, or Bacillus coagulans) or engineered non-mycotoxigenic Rhizopus oryzae strains operating at 38 °C to 52 °C for 36 to 60 hours.
Through the Embden-Meyerhof-Parnas (EMP) glycolytic pathway, each 1 mole of six-carbon D-glucose (C6H12O6) is cleaved into 2 moles of pyruvate, which stereoselective NAD+-dependent L-lactate dehydrogenase reduces quantitatively into 2 moles of L-(+)-Lactic Acid (C3H6O3) at a carbon yield exceeding 95% to 98% and an enantiomeric excess (ee) of > 98.0% L-(+)-isomer:
C6H12O6 (Plant Glucose) -> 2 CH3-CH(OH)-COOH (L-(+)-Lactic Acid)
Stage 2: Downstream Purification of Lactic Acid (Membrane Filtration, Acidulation, and Vacuum Distillation / Ester Hydrolysis):
In traditional gypsum-based fermentation (where CaCO3 or Ca(OH)2 is added to maintain fermenter pH at 5.5 to 6.2), the resulting calcium lactate broth is microfiltered to remove 100% of bacterial cells and proteins, acidified with sulfuric acid to precipitate calcium sulfate dihydrate (gypsum), filtered, decolorized over activated carbon, and passed through strong-acid cation and weak-base anion exchange resin columns. In advanced gypsum-free membrane processes (or direct NaOH-buffered fermentation), ultrafiltration, nanofiltration, bipolar membrane electrodialysis, or short-path molecular vacuum distillation (at 115 °C to 135 °C under 1 to 5 mbar absolute pressure) isolates ultra-pure, water-white monomer L-(+)-Lactic Acid completely free of residual reducing sugars, proteins, amino acids, or colored Maillard precursors.
Stage 3: Stoichiometric Neutralization and Lactoyl-Lactate Dimer Saponification with Membrane-Grade Sodium Hydroxide:
Concentrated lactic acid always contains 5% to 15% of intermolecular ester oligomers—specifically lactoyl-lactic acid linear dimers (CH3CH(OH)CO-OCH(CH3)COOH) and cyclic lactide. If lactic acid were simply mixed with cold sodium hydroxide at room temperature, only the free monomer acid would neutralize immediately, while the lactoyl-lactate dimers would slowly hydrolyze over weeks in storage, causing the solution pH to drift downward from 7.0 to 4.5!
To eliminate pH drift completely, purified L-lactic acid (or DL-lactic acid) is reacted in a jacketed 316L stainless-steel reactor at 75 °C to 95 °C with a slight stoichiometric excess of high-purity membrane-cell Sodium Hydroxide (NaOH, 32% to 50% w/w) for 1 to 2 hours. This hot alkaline digestion saponifies 100% of all lactoyl-lactic acid dimers and cyclic lactide into monomeric Sodium Lactate:
CH3-CH(OH)-COOH + NaOH -> CH3-CH(OH)-COONa + H2O (Enthalpy of Neutralization: Delta H = -56.2 kJ/mol)
Inline pH electrodes then trim the reactor with a trace of pure lactic acid to lock the final equilibrium pH at 6.8 to 7.2.
Stage 4: Activated-Carbon Polishing, Vacuum Concentration to 60.0% w/w, and 0.2-Micron Sterile Filtration:
The neutralized Sodium Lactate liquor is polished through steam-activated microporous coconut-shell carbon beds and chelating ion-exchange columns (stripping Fe, Cu, and Pb below 0.1 ppm), concentrated in falling-film vacuum evaporators at 55 °C to 65 °C to an exact refractive index (nD20 = 1.4235) and density (1.325 g/cm3) corresponding to 60.0% +/- 0.5% w/w C3H5NaO3, and passed through 0.22-micron pharmaceutical-grade PVDF membrane filters into clean HDPE drums, IBC totes, or ISO tankers.
MECHANISM OF ACTION: WATER ACTIVITY DEPRESSION, LISTERIA BACTERIOSTASIS, AND NMF SKIN HYDRATION
Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, E325) delivers its multi-industry functionality through four distinct, quantitatively established physicochemical and biological mechanisms:
Dual-Mechanism Bacteriostasis Against Listeria monocytogenes and Clostridium botulinum in Meat, Poultry, and Seafood:
When E325 Sodium Lactate 60% is incorporated into cooked sausages, frankfurters, deli hams, roast beef, smoked fish, or fresh pork/poultry sausages at 2.0% to 4.8% w/w (delivering 1.2% to 2.88% w/w anhydrous Sodium Lactate in the finished meat), it extends refrigerated shelf life by 50% to 150% and arrests the outgrowth of psychrotrophic Listeria monocytogenes, Clostridium botulinum, Salmonella enterica, Escherichia coli O157:H7, and lactic acid spoilage bacteria through two simultaneous hurdles—even at neutral meat pH (pH 5.8 to 6.5) where traditional weak-acid preservatives like sodium benzoate (pKa 4.20) failed:
- Mechanism A — Thermodynamic Water Activity (aw) Depression via Ion-Dipole Hydration: Because Sodium Lactate has a low molecular weight (112.06 g/mol) and dissociates completely into strongly hydrated Na+ and CH3CH(OH)COO- ions, adding 3.0% w/w of Sodium Lactate 60% (1.8% anhydrous salt) depresses the internal water activity (aw) of a cooked meat emulsion from ~0.985 down to ~0.968–0.972. This osmotic shock forces bacteria to expend metabolic ATP synthesizing compatible solutes (betaine, proline) simply to prevent plasmolysis, extending the microbial lag phase by 10 to 30 days at 4 °C!
- Mechanism B — Lactate-Specific Intracellular Feedback Inhibition and Proton-Shuttle Uncoupling: At pH 5.8 to 6.2 in meat (with conjugate lactic acid pKa = 3.86), approximately 0.5% to 1.8% of the total dissolved lactate exists as lipophilic, uncharged undissociated lactic acid (CH3CH(OH)COOH). This uncharged lactic acid diffuses passively across the cytoplasmic lipid bilayer of Listeria monocytogenes and dissociates inside the neutral bacterial cytoplasm (pHi ~7.0), releasing protons (H+) that collapse the transmembrane proton-motive force and exhaust membrane H+-ATPase pumps. Simultaneously, the high extracellular concentration of lactate anions (150 to 270 mM) reverses or stalls the bacterial fermentative enzyme Lactate Dehydrogenase (LDH) via Le Chatelier mass-action feedback inhibition, preventing anaerobic bacteria (including fermentative lactic spoilage flora and proteolytic/non-proteolytic Clostridium botulinum) from regenerating NAD+ from NADH during glycolysis!
- Synergy with Sodium Diacetate (E262): When 2.5% to 3.0% w/w of Sodium Lactate 60% is co-formulated with 0.15% to 0.25% w/w of Sodium Diacetate (a 9:1 to 14:1 blend), the lower-pKa lactate depresses aw and blocks LDH glycolysis while the higher-pKa acetate (pKa 4.76, having 6 times more undissociated acid at pH 6.0) floods the bacterial cytoplasm with protons—providing USDA-FSIS "Alternative 1 / Alternative 2" bactericidal control that completely prevents Listeria monocytogenes growth across 90 to 120 days of refrigerated deli storage!
Myofibrillar Protein Ionic-Strength Hydration and Cooking-Loss Reduction in Meat Matrices:
In whole-muscle injected hams, bacon, poultry breasts, and comminuted sausages (sucuk, salami, frankfurters, meatballs), Sodium Lactate 60 % increases ionic strength without harsh NaCl astringency. The lactate anions bind to positively charged amino acid side chains on myofibrillar actomyosin filaments, shifting the protein net charge away from its isoelectric point (pI ~5.2) and creating electrostatic repulsion between actin and myosin fibers. This expands the inter-filament space to immobilize free water, cutting thermal purge / cooking weight loss by 3% to 8%, eliminating syneresis ("weeping") in vacuum-packed sliced deli meats, and improving sliceability and bite juiciness.
Biomimetic Stratum Corneum Hydration (Natural Moisturizing Factor — NMF) and Keratin Plasticization in Cosmetics:
In healthy human epidermis, the stratum corneum maintains its suppleness and barrier integrity through an intracellular cocktail of hygroscopic small molecules known as the Natural Moisturizing Factor (NMF), which constitutes 20% to 30% of the dry weight of corneocytes. Quantitative dermatological analysis shows that physiological L-Lactate (primarily as Sodium Lactate) accounts for 12% of the entire human NMF pool (second only to free amino acids and pyrrolidone carboxylic acid PCA)!
When INCI-grade Sodium Lactate 60 % is applied topically in creams, lotions, serums, shampoos, or body washes at 1.0% to 5.0% w/w:
- Superior Water-Holding Capacity Over Glycerin: Because the alpha-hydroxyl and carboxylate oxygens of Sodium Lactate form a bridged bidentate hydration complex with water and corneocyte keratin chains, Sodium Lactate exhibits nearly twice the equilibrium moisture-retention capacity of glycerin at 50% relative humidity and increases stratum corneum skin hydration by up to 84% in clinical corneometry studies—while leaving a silky, non-tacky skin feel!
- Corneocyte Keratin Plasticization and Ceramide Synthesis Stimulation: Even when relative humidity drops below 40% (where simple humectants can draw water out of the dermis), Sodium Lactate acts as an intrinsic molecular plasticizer that intercalates between keratin filaments inside corneocytes to maintain skin elasticity and prevent winter flaking/cracking, while biologically stimulating epidermal keratinocyte synthesis of barrier ceramides and filaggrin.
- Post-Bleaching and Post-Dyeing Hair Cuticle pH Buffering and Cortex Hydration: In professional hair care, alkaline bleaching and permanent hair dyeing (pH 9.0 to 11.0) strip natural NMF from the hair shaft and swell cuticle scales. Incorporating 1.0% to 3.0% w/w of Sodium Lactate 60 % into post-color shampoos, conditioners, and hair masks buffers the hair back to its physiological acidic range (pH 4.5 to 5.5), flattens and closes cuticle scales for high optical gloss, binds moisture inside the hair cortex to restore tensile elasticity, and reduces scalp chemical irritation.
Mechanism of Cold-Process and Hot-Process Soap Bar Hardening and Fluidity:
In artisanal and industrial saponified bar soaps (especially high-olive-oil Castile soaps or palm-free vegetable soaps), dosing 1.5% to 3.0% w/w of Sodium Lactate 60 % into the cooled sodium hydroxide (NaOH) lye solution before mixing with oils increases the sodium ion concentration (common-ion effect) while simultaneously binding free water in the curing soap matrix. In Cold Process (CP) soap, this reduces soft soap curds, allows clean unmolding in 12 to 24 hours instead of 3 to 5 days, prevents bar cracking, and yields a harder, longer-lasting bar that resists mushiness in the shower dish. In Hot Process (HP) soap, Sodium Lactate keeps the cooked soap batter fluid and pourable at 80 °C, eliminating crumbly "mashed-potato" batter texture and imparting a smooth, translucent, glossy finish.
COMPREHENSIVE APPLICATIONS ACROSS GLOBAL INDUSTRIES
Meat, Poultry, Charcuterie, and Seafood Processing (Food Additive E325 / USDA-FSIS / EU Reg. 1333/2008):
The processed meat, poultry, and charcuterie sector accounts for the largest global volume of Food Grade E325 Sodium Lactate 60%:
- Cooked, Emulsified, and Fermented Sausages (Frankfurters, Hot Dogs, Bologna, Mortadella, Salami, Sucuk, Pepperoni, Bratwurst, Cooked Minced Meat, and Meatballs/Köfte): Added directly to the bowl chopper or mixer at 2.0% to 4.0% w/w of the 60% liquid solution (delivering 1.2% to 2.4% w/w anhydrous Sodium Lactate; authorized up to 4.8% anhydrous salt / 8.0% of 60% solution under USDA-FSIS 9 CFR 424.21, and at "quantum satis" in pre-packed minced meat and meat preparations under EU Regulation 1333/2008). E325 Sodium Lactate 60% suppresses Listeria monocytogenes, Salmonella, and souring lactic acid bacteria, extends vacuum-packed and MAP refrigerated shelf life from 30 days to 60–90+ days, reduces smokehouse and cooking weight loss, improves cohesive firmness and high-speed slicing performance, and rounds out spice and salt flavor profiles.
- Injected, Pumped, and Tumbler-Cured Whole-Muscle Meats (Cooked Ham, Smoked Turkey Breast, Roast Beef, Bacon, Pastrami, and Marinated Chicken/Beef Cuts): Dissolved directly into chilled injection pickle brines (at 10% to 25% w/w in the brine for a 15% to 30% pump rate, delivering 2.5% to 4.0% of 60% solution in the finished meat). Unlike dry powders that require prolonged agitation, liquid Sodium Lactate 60 % disperses in seconds into cold (0 °C to 4 °C) phosphate-nitrite-erythorbate curing brines without altering brine pH or causing protein precipitation, protecting cold-chain quality continuity and retaining natural muscle juiciness.
- Fresh and Smoked Seafood, Fish Fillets, Surimi, and Shrimp: Applied at 1.5% to 3.5% w/w in marinades, injection brines, or dipping solutions for cold-smoked salmon, trout, whitefish fillets, and cooked shrimp to inhibit psychrotrophic Listeria monocytogenes and Clostridium botulinum Type E without imparting a fishy or acidic taste.
Bakery, Confectionery, Sauces, Ready-to-Eat Meals, and Low-Sodium Foods (E325 / FCC):
- Bakery Products, Breads, Tortillas, Cakes, and Pastries: Dosed at 0.5% to 2.0% w/w on flour weight in sandwich breads, buns, tortillas, sponge cakes, and bakery fillings. As a non-volatile food humectant (aw = 0.78–0.81), Sodium Lactate 60 % binds free moisture in the starch-gluten crumb network, retarding amylopectin retrogradation (staling), keeping baked goods soft and flexible over extended shelf life, and suppressing rope-forming Bacillus subtilis and surface molds.
- Ready-to-Eat (RTE) Meals, Deli Salads, Pasta Sauces, Dressings, and Soups: Incorporated at 1.0% to 3.0% w/w into chilled ready meals, potato/chicken/seafood deli salads, emulsified sauces, and gravies to stabilize water binding during freeze-thaw and microwave reheating cycles, regulate pH, and inhibit spore-forming and pathogenic bacteria.
- Sodium-Reduction Synergist in Savory Foods: Because anhydrous Sodium Lactate contains only 20.52% sodium (and 60% solution contains only 12.31% sodium—less than one-third the sodium content of NaCl table salt at 39.34% Na!) while stimulating salty and umami taste receptors, replacing 25% to 40% of NaCl with E325 Sodium Lactate reduces total product sodium content by 20% to 30% without sacrificing savory saltiness or microbial water-activity protection.
- Confectionery, Hard Candies, Gummies, Dairy Products, and Functional Beverages: Used as an inversion-controlling pH buffer in boiled sweets and pectin gummies (preventing premature pectin pre-gelation and sticky sucrose inversion), as an emulsifying/buffering salt in processed cheese spreads and ice cream mixes, and as an electrolyte and pH-stabilizing buffer in sports drinks, energy drinks, functional hydration beverages, and specialized medical nutrition solutions.
Cosmetics, Dermatology, Hair Care, and Soap Manufacturing (INCI: SODIUM LACTATE):
- Leave-On Facial Moisturizers, Anti-Aging Serums, Body Lotions, and Barrier Creams: Dosed at 1.0% to 5.0% w/w (up to 10% w/w at formulation pH >= 3.5 per Cosmetic Ingredient Review CIR safety guidelines) as a physiological NMF humectant, often paired 2:1 or 1:1 with Sodium PCA, glycerin, urea, or hyaluronic acid. It increases skin hydration by up to 84%, relieves xerosis (dry, flaky skin), improves emulsion spreadability and freeze-thaw stability, and acts as a mild skin-brightening and keratolytic co-active.
- AHA Chemical Peels and Exfoliating Toners (Buffered Lactic Acid Systems): Blended with free Lactic Acid (CAS 79-33-4) to create a true Henderson-Hasselbalch buffer (pH 3.5 to 4.5). Buffering an AHA peel with INCI Sodium Lactate prevents sudden pH spikes or drops on the skin, delivers a controlled reservoir of gentle keratolytic renewal, and drastically reduces neurosensory stinging, burning, and erythema.
- Shampoos, Liquid Body Washes, Intimate Washes, and Post-Color Hair Repair Masks: Incorporated at 0.5% to 3.0% w/w to hydrate the scalp and hair cortex, buffer post-bleaching/post-perm hair back to pH 4.5–5.5 (closing cuticle scales for enhanced shine and tensile strength), and boost surfactant viscosity and lather creaminess.
- Cold-Process (CP), Hot-Process (HP), and Liquid Soap Manufacturing: Added at 1.5% to 3.0% w/w of total soap oils (1 teaspoon / ~5 mL per pound of oils) directly into the cooled lye water. Hardens CP soap bars 2 to 3 times faster for clean, dent-free unmolding within 12 to 24 hours, prevents soda ash and cracking, and keeps HP soap batter fluid and pourable for intricate swirl designs and glossy bar surfaces.
Pharmaceutical, Parenteral, Dialysis, and Veterinary Formulations (USP / Ph. Eur. / BP):
- Intravenous Balanced Crystalloid Solutions (Ringer's Lactate / Hartmann's Solution / Compound Sodium Lactate Injection): Included on the World Health Organization (WHO) Model List of Essential Medicines, Pharmaceutical Grade Sodium (S)-Lactate Solution (USP / Ph. Eur. Monograph 2116) is the active alkalinizing electrolyte component (typically at 28 to 29 mmol/L, ~3.1 to 3.2 g/L anhydrous equivalent) in Compound Sodium Lactate Injection for trauma resuscitation, burn fluid therapy, surgical fluid replacement, and treatment of mild-to-moderate metabolic acidosis (where hepatic oxidation via the Cori cycle and tricarboxylic acid cycle converts 1 mole of L-lactate into 1 mole of plasma bicarbonate HCO3- over 1 to 2 hours without the gas-generating risk of direct sodium bicarbonate infusion). Also utilized clinically in managing cardiac arrhythmias caused by Class I antiarrhythmic or tricyclic antidepressant overdose.
- Peritoneal Dialysis and Hemofiltration Solutions: Serves as the physiological pH-buffering base (at 35 to 40 mmol/L) in sterile peritoneal dialysis fluids where sodium bicarbonate would precipitate calcium and magnesium ions during heat sterilization in PVC/polyolefin bags.
- Veterinary Topical, Hygiene, and Parenteral Preparations: Used in veterinary intravenous rehydration fluids, udder hygiene teat dips, and dermatological ear/skin washes for moisture management and physiological pH control.
Industrial, Leather, Textile, Fermentation Bioprocessing, and Eco-Deicing Applications:
- Leather Tanning, Deliming, and Fatliquoring: Used in leather wet-end processing as a mild, non-swelling pH buffer and humectant that promotes uniform chrome/vegetable tannin penetration and keeps finished leather supple without cracking in dry air.
- Textile Printing, Dyeing, and Finishing: Functions as a non-volatile, non-corrosive hygroscopic humectant in vat and reactive textile printing pastes (absorbing steam moisture during aging to accelerate dye fixation) and as an antistatic fiber conditioning agent.
- Industrial Biotechnology & Fermentation pH/Carbon Control: Utilized as a buffered carbon source, osmoprotectant, and pH stabilizer in specialty microbial and cell-culture fermentations.
- Eco-Friendly Industrial Surface Cleaners, Kitchen Hygiene, and CIP Systems: Utilized in green water-based industrial surface cleaners, food-plant equipment cleaners, CIP (Clean-In-Place) systems, glass cleaners, and metal/non-metal surface treatment baths to stabilize formulation pH, prevent surfactant phase separation, and complex trace water hardness with zero toxicity and complete biodegradability.
- Environmentally Benign Runway/Road Deicers, Antifreeze Brines, and Paper/Tobacco Humectants: Used as a chloride-free, non-corrosive, readily biodegradable freezing-point depressant and secondary heat-transfer coolant, as well as a plasticizer/humectant in specialty papers, cellulose films, semiconductor/optical component cleaning, and tobacco conditioning.
FORMULATION AND PROCESS ENGINEERING GUIDELINES
To achieve optimal microbial shelf-life extension, meat cooking yield, cosmetic emulsion stability, and soap-molding performance when formulating with Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, E325), process engineers and R&D chemists should implement the following quantitative engineering guidelines:
Meat, Poultry, and Charcuterie Dosing & Brine Engineering Protocol:
- Standard Dosage Calculation (Converting 60% Solution to Anhydrous Basis):
* For 30-to-45-day refrigerated shelf-life extension and 4%–6% cooking yield improvement in cooked sausages (frankfurters, salami, sucuk, bologna): dose 2.5% to 3.3% w/w of Sodium Lactate 60 % Solution based on total meat batter weight (delivering 1.5% to 2.0% w/w anhydrous Sodium Lactate).
* For maximum 60-to-120-day Listeria monocytogenes zero-growth control in RTE sliced deli meats (ham, turkey breast, roast beef): dose 3.0% to 4.8% w/w of Sodium Lactate 60 % Solution (delivering 1.8% to 2.88% w/w anhydrous Sodium Lactate) co-formulated with 0.15% to 0.25% w/w of Sodium Diacetate (E262).
- Whole-Muscle Injection Pickle Brine Formula by Pump Rate:
Brine % of Sodium Lactate 60% = [Target Finished Meat % of Sodium Lactate 60% x (100 + % Pump)] / % Pump
* At 15% Injection Pump (to deliver 3.0% of Sodium Lactate 60% in finished meat): include 23.0% w/w of Sodium Lactate 60 % Solution in the pickle brine.
* At 20% Injection Pump (to deliver 3.0% of Sodium Lactate 60% in finished meat): include 18.0% w/w of Sodium Lactate 60 % Solution in the pickle brine.
* At 30% Injection Pump (to deliver 3.0% of Sodium Lactate 60% in finished meat): include 13.0% w/w of Sodium Lactate 60 % Solution in the pickle brine.
- Brine Mixing Sequence & NaCl Adjustment: In injection brines, dissolve alkaline polyphosphates (STPP) in chilled water (0 °C to 4 °C) first, then add Sodium Chloride, followed by liquid Sodium Lactate 60 % (which mixes instantly), and finally Sodium Erythorbate and Sodium Nitrite. Because 3.0% w/w of Sodium Lactate 60% contributes mild savory saltiness equivalent to ~0.4%–0.5% NaCl, formulators typically reduce added NaCl by 0.25% to 0.50% w/w to maintain an ideal, balanced flavor profile without excessive saltiness.
Cosmetic Emulsion, Serum, and Buffered AHA Peel Formulation Protocol:
- Electrolyte-Sensitive Rheology Considerations: Because Sodium Lactate 60 % is an ionic organic salt (containing 5.35 moles of Na+ per kg of 60% solution), adding 2.0% to 5.0% w/w of INCI Sodium Lactate to an O/W cream or gel substantially increases aqueous ionic strength. Standard non-crosslinked carbomers (Carbomer 940 / 980) collapse in viscosity when exposed to > 0.5% electrolytes! Therefore, when formulating creams or serums with 2.0% to 5.0% Sodium Lactate 60 %, always select electrolyte-tolerant rheology modifiers—such as Xanthan Gum, Sclerotium Gum, Hydroxyethylcellulose (HEC), Polyacrylate Crosspolymer-6, or Ammonium Polyacryloyldimethyl Taurate—coupled with nonionic or liquid-crystal emulsifiers (e.g., Cetearyl Alcohol + Cetearyl Glucoside or Glyceryl Stearate + PEG-100 Stearate).
- Order of Addition in Emulsions: Add Sodium Lactate 60 % either to the heated aqueous phase (Phase A, as it is thermally stable past 100 °C) or during the cool-down phase below 45 °C.
- Calculating Henderson-Hasselbalch Buffered AHA Peels (pKa = 3.86):
pH = 3.86 + log10([Moles Sodium Lactate] / [Moles Free Lactic Acid])
* For a pH 3.86 Buffered 10% Total Lactic Equivalent Peel: combine 1.00 molar equivalent of Lactic Acid (e.g., 5.56% w/w of 90% Lactic Acid) with 1.00 molar equivalent of Sodium Lactate (e.g., 10.37% w/w of Sodium Lactate 60 % Solution).
* For a milder pH 4.16 Buffered Peel: use a 2.0 : 1.0 molar ratio of Sodium Lactate to Free Lactic Acid.
Cold-Process and Hot-Process Bar Soap Engineering Protocol:
- Dosage: Use 1.5% to 3.0% w/w of Sodium Lactate 60 % based on total oil weight (standard benchmark: 2.0% w/w, or 20 grams of Sodium Lactate 60 % per 1,000 grams of soap oils). Do not exceed 3.5% to 4.0% w/w in Cold Process soap, as overdosing causes brittle, chalky, or crumbly bars if cut too late.
- Addition Step: Stir the weighed Sodium Lactate 60 % directly into the cooled aqueous NaOH lye solution (at 35 °C to 50 °C) just before pouring the lye into the melted oils (or stir into the hot water before adding to cooked Hot Process soap paste). Note that Sodium Lactate 60 % is already a neutral salt and does NOT consume any NaOH lye (zero saponification value adjustment required!).
COMPARATIVE ADVANTAGES: WHY SODIUM LACTATE 60 % IS PREFERRED OVER COMPETING CHEMICALS
Formulators, meat technologists, cosmetic chemists, and procurement specialists consistently choose liquid Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, E325) over dry lactate powders, competing organic salts, polyols, and synthetic preservatives due to six decisive technical and economic advantages:
Liquid Sodium Lactate 60 % vs. Anhydrous Crystalline Sodium Lactate Powder (96%–98% Solid):
Anhydrous solid Sodium Lactate powder is one of the most intensely hygroscopic and deliquescent powders in industrial chemistry: the moment a bag or drum of dry Sodium Lactate powder is opened in a normal factory environment (> 30%–40% relative humidity), the powder rapidly absorbs moisture from the air, liquefied at particle edges, and fuses into a rock-hard or sticky, un-scoopable mass, while costing 2.5 to 4 times more per kilogram of active salt due to energy-intensive vacuum spray/drum drying! By contrast, Sodium Lactate 60 % is supplied in its natural, thermodynamically stable aqueous liquid state (aw ~0.79): it never cakes, generates zero airborne dust, can be pumped directly from IBC totes or drums via automated metering pumps, dissolves instantaneously in cold water (0 °C to 25 °C) without exothermic heat of hydration, and delivers the lowest cost per kilogram of active C3H5NaO3.
Sodium Lactate 60 % (E325) vs. Potassium Lactate 60 % (CAS 996-31-6 / E326):
While Potassium Lactate 60% is used in specialized zero-sodium products, the potassium cation (K+) imparts a characteristic metallic, slightly bitter, acrid aftertaste when dosed above 2.0% to 2.5% w/w in delicate poultry, pork, or bakery items, and Potassium Lactate has a higher molecular weight (128.17 g/mol vs. 112.06 g/mol for Sodium Lactate, meaning 1.0 kg of Sodium Lactate 60% delivers 14.4% more molar water-activity-depressing lactate ions than 1.0 kg of Potassium Lactate 60%!) and a higher raw-material price due to KOH cost. Furthermore, in Cold-Process bar soap making, Potassium Lactate softens the soap bar (since potassium soaps are liquid/soft soaps), whereas Sodium Lactate 60 % supplies Na+ ions that harden the soap bar rapidly!
Sodium Lactate 60 % vs. Unneutralized Lactic Acid 80% / 88% (CAS 50-21-5 / 79-33-4 / E270):
Concentrated 80%–88% Lactic Acid is strongly acidic (pH < 1.8) and corrosive. Adding free Lactic Acid directly to a meat emulsion, milk protein beverage, or O/W cosmetic cream above 0.3%–0.5% drops the pH below the isoelectric point of myofibrillar actomyosin or casein (pH 4.6–5.2), causing immediate protein curdling, denaturing purge/water loss, nitrite NO2 gas evolution in cured meat brines, and severe skin stinging in cosmetics. Because Sodium Lactate 60 % is pre-neutralized to pH 6.5 to 7.5, it can be dosed at 2.0% to 5.0% w/w into neutral meat batters, curing brines, and delicate skin creams without shifting formulation pH or denaturing proteins!
Sodium Lactate 60 % vs. Sodium Benzoate (E211), Potassium Sorbate (E202), and Calcium Propionate (E282):
Benzoates (pKa 4.20) and sorbates (pKa 4.76) require an acidic matrix (pH <= 4.5 to 5.0) to function and are either ineffective or legally restricted in fresh and cooked meat, poultry, and seafood products (whose natural pH is 5.8 to 6.5), while propionates impart a pungent, cheesy off-odor. E325 Sodium Lactate 60% operates effectively across neutral pH 5.5 to 7.0 via combined water-activity depression and lactate-dehydrogenase feedback inhibition, is universally authorized in meat and poultry products, and imparts zero off-odor.
Sodium Lactate 60 % vs. Glycerin (Glycerol, E422) and Propylene Glycol (E1520) in Cosmetics and Humectancy:
In leave-on skin care and hair care, dosing high levels (> 5%) of glycerin creates a heavy, tacky, sticky drag on the skin, and at low ambient humidity (< 30% RH) uncomplexed glycerin can feel drying, whereas petrochemical propylene glycol can cause dermal irritation and lacks natural NMF identity. As a physiological ionic NMF constituent, INCI Sodium Lactate 60 % binds nearly twice as much water per gram as glycerin at 50% RH, plasticizes corneocyte keratin directly, leaves a lightweight, powdery-smooth, non-sticky finish, and simultaneously buffers formulation pH.
Sodium Lactate 60 % vs. Sodium Chloride (NaCl) in Meat Brines and Soap Hardening:
Adding extra NaCl (> 2.2%–2.5%) to meat products to lower water activity makes the food unpalatably salty and raises dietary sodium to unhealthy levels (39.34% Na in NaCl). Sodium Lactate 60 % contains less than one-third the elemental sodium of NaCl (12.31% Na in 60% solution), allowing meat processors to depress water activity and boost protein water-binding yield while maintaining a mild, pleasant savory taste. In cold-process soap making, adding NaCl brine above 1% "salts out" fatty acid soaps and kills lather completely, whereas 2% to 3% Sodium Lactate 60 % hardens the bar and accelerates unmolding while preserving rich, creamy lather!
PACKAGING, STORAGE AND HANDLING GUIDELINES
Although Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, E325) is a chemically stable, non-volatile, non-flammable, and non-corrosive aqueous solution, proper warehouse temperature management and sanitary liquid-handling practices are essential to preserve its water-white APHA color, microbiological purity, and crystal-free pumpability:
Standard Commercial Packaging Formats Supplied by Ataman Kimya:
- 25 kg and 30 kg Net High-Density Polyethylene (HDPE) Jerrycans / Carboys: Equipped with tamper-evident screw caps and inner seals for cosmetic laboratories, artisanal/industrial soap makers, bakeries, and medium-scale charcuterie plants (standard palletization: 24 to 36 jerrycans = 600 kg to 1,080 kg net on shrink-wrapped ISPM-15 pallets).
- 240 kg, 250 kg, and 260 kg Net Tight-Head Food/Pharma-Grade HDPE Plastic Drums: Standard industrial drum format (4 drums = 960 kg to 1,040 kg net per pallet) taking advantage of the high 1.325 g/cm3 specific gravity of Sodyum Laktat %60.
- 1,250 kg and 1,300 kg Net Composite Intermediate Bulk Containers (IBC Totes): Food-grade UV-stabilized HDPE inner bottle inside a galvanized tubular steel cage with a bottom DN50 butterfly discharge valve and top vent cap for automated meat-brine, bakery, and detergent/cosmetic dosing lines.
- 24,000 kg to 26,000 kg Net Insulated 316L Stainless-Steel Bulk Road Tankers and ISO Tank Containers: Available for high-volume industrial meat-processing and personal-care plants.
Warehouse Storage Conditions for Sodium Lactate 60 %:
- Optimal Storage Temperature and Frost Protection (Preventing Reversible Cold Crystallization): Store Sodium Lactate 60 % Solution in a clean, dry, well-ventilated indoor warehouse maintained at ambient temperatures between 10 °C and 30 °C (ideally 15 °C to 25 °C), protected from direct sunlight, high-temperature steam radiators, and sub-zero winter freezing. Because stereochemically pure 60% w/w Sodium L-(+)-Lactate Solution is near its thermodynamic saturation threshold at low temperatures, prolonged winter exposure below +5 °C to +10 °C (or below -10 °C for racemic DL-grades) can induce slow, reversible nucleation of white needle-like Sodium Lactate crystals at the bottom of drums or IBC totes. Note that cold crystallization does NOT degrade the chemical or microbiological quality of Lactic Acid Sodium Salt 60% in any way: if crystals appear after winter transit, simply move the closed drum or IBC tote into a warm room (25 °C to 40 °C) or apply a thermostatically controlled drum/IBC heating blanket (< 50 °C) with gentle circulation or rolling until the crystals redissolve completely into a crystal-clear, homogeneous 60% solution before pumping.
- Protection Against Prolonged High Heat (> 40 °C): Avoid storing E325 Sodium Lactate 60% above 40 °C to 45 °C for extended months, as prolonged thermal exposure can gradually increase the APHA color index from water-white (< 20 APHA) toward pale yellow and alter its neutral odor profile.
- Container Resealing and Hygroscopic Moisture Equilibrium: Always reseal drum bungs, jerrycan caps, and IBC lids tightly immediately after dispensing. If containers of Monosodium Lactate 60% are left open in very humid environments (> 80% RH), the hygroscopic solution absorbs atmospheric moisture and dilutes below 60% w/w; conversely, if left open in dry heated air (< 50% RH), surface water evaporation forms a supersaturated crystalline crust around the cap threads and pump nozzles.
- Chemical Segregation: Store Sodium 2-Hydroxypropanoate 60% segregated from strong oxidizing agents (such as concentrated nitric acid, hydrogen peroxide > 30%, perchlorates, chlorates, chromic acid, and permanganates) and strong mineral acids.
- Shelf Life and Retest Period: When stored unopened in original food/cosmetic-grade HDPE containers at 15 °C to 25 °C, Sodium Lactate 60 % maintains full compendial specification compliance for 24 to 36 months (2 to 3 years) from the date of manufacture. Rotate inventory using First-In, First-Out (FIFO) / First-Expired, First-Out (FEFO) discipline.
Safe Industrial Handling, Transfer Lines, and Compatible Materials:
- Compatible Equipment Materials: At neutral pH (6.5 to 7.5), Sodium Lactate 60 % is completely non-corrosive and compatible with 304 and 316L stainless steel, high-density polyethylene (HDPE), polypropylene (PP), PVC, PTFE, glass, and Viton/EPDM/nitrile elastomers. Avoid unlined carbon steel, cast iron, copper, brass, and zinc/galvanized surfaces in direct contact with the liquid to prevent trace metal leaching (Fe or Cu > 5 ppm) and discoloration.
- Sanitary Transfer Lines and Slip-Hazard Prevention: Maintain closed, sanitary transfer lines and flush dosing pumps periodically with warm potable water to prevent dried crystal buildup on pump seals. Because spilled 60% syrupy solutions of Sodyum Laktat create an extremely slick, slippery film on smooth factory floors, contain and wash down any drips or spills immediately.
FIRST AID MEASURES AND SAFETY INFORMATION
Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, EC 200-772-0 / 212-762-3, E325) is an exceptionally safe, non-toxic, physiological organic salt solution: L-lactate is a natural intermediary metabolite of human carbohydrate metabolism and human skin NMF, exhibits very low acute toxicity (oral LD50 in rats > 2,000 to 5,000+ mg/kg body weight; dermal LD50 > 2,000 mg/kg), is non-mutagenic and non-sensitizing, and is NOT classified as a hazardous substance or mixture under European Union CLP Regulation (EC) No 1272/2008 or UN GHS criteria. Nevertheless, because Sodium Lactate 60 % is a hypertonic, concentrated electrolyte syrup (~14.2 Osmol/L), direct splashes into the eyes or prolonged contact with abraded skin can cause transient osmotic stinging or mild mechanical irritation. Ensure that the following first aid and industrial hygiene procedures are followed wherever Lactic Acid Sodium Salt 60% is handled:
First Aid Measures by Route of Exposure:
- Eye Contact with Sodium Lactate 60 %: If liquid splashes or aerosols of Sodium Lactate 60 % (E325 Sodium Lactate / Monosodium Lactate Solution) enter the eyes, immediately flush the eyes with plenty of lukewarm, gently flowing potable water or sterile isotonic saline eyewash solution for at least 15 minutes, holding the upper and lower eyelids wide open to irrigate the entire conjunctival surface. Remove contact lenses after the first 5 minutes if present and easy to do, then continue rinsing. Because hypertonic 60% w/w Sodium 2-Hydroxypropanoate draws water osmotically from the tear film and causes immediate transient stinging, redness, or watering, consult a physician or ophthalmologist if ocular irritation persists after rinsing.
- Skin Contact with Sodium Lactate 60 %: Remove any syrup-soaked work clothing or shoes and wash the affected skin thoroughly with mild soap and running water. At pH 6.5 to 7.5, INCI Sodium Lactate 60 % is non-corrosive, non-sensitizing, and actively beneficial as a skin humectant at cosmetic dilutions (1% to 10%); however, prolonged occluded contact with undiluted 60% hypertonic syrup on chapped or broken skin may cause mild osmotic tingling or redness. Launder contaminated work clothes before reuse, and seek medical advice if skin irritation develops.
- Inhalation of Sodium Lactate 60 % Mist or Aerosols: Because Sodium Lactate 60 % is a non-volatile ionic salt solution, no hazardous vapors are emitted at ambient temperatures. However, if a worker inhales airborne mists or aerosols generated during high-pressure spraying or heated handling of Sodyum Laktat %60 in an enclosed space, move the exposed person immediately into fresh air and keep them comfortable and at rest. Have the individual rinse their nose, mouth, and throat with clean water. If breathing is difficult or coughing persists, administer oxygen if trained and consult a physician.
- Accidental Ingestion of Bulk Sodium Lactate 60 %: Food Grade E325 Sodium Lactate is a safe, GRAS food additive at normal dietary levels. If a large industrial volume (> 50 to 100 mL) of concentrated 60% Lactic Acid Sodium Salt is accidentally swallowed at once, rinse the mouth thoroughly with water and have the conscious, alert person drink 200 to 300 mL (1 to 2 glasses) of water to dilute the hypertonic sodium load in the stomach. Do NOT induce vomiting, and never give anything by mouth to an unconscious person. Swallowing massive bulk doses of concentrated Sodium Lactate 60 % can cause acute osmotic gastrointestinal distress, nausea, abdominal cramping, osmotic diarrhea, hypernatremia (elevated blood sodium), or metabolic alkalosis; seek medical attention if a large quantity is ingested.
Personal Protective Equipment (PPE) and Workplace Hygiene:
- Eye and Face Protection: Wear standard side-shield safety glasses or tightly fitting chemical splash goggles conforming to EN 166 (EU) or ANSI Z87.1 (US) whenever pumping, pouring, or diluting drums and IBC totes of Sodium Lactate 60 % (and add an 8-inch face shield if handling pressurized transfer lines).
- Hand and Body Protection: Wear standard impervious chemical-resistant gloves made of nitrile rubber (minimum layer thickness >= 0.11 mm to 0.30 mm, breakthrough time > 480 minutes Class 6 per EN ISO 374-1), butyl rubber, latex, or neoprene, along with standard protective workwear and non-slip safety boots.
- Respiratory Protection: No respiratory protection is required during normal ambient liquid handling under general room ventilation; if high-pressure spraying or heated agitation generates concentrated airborne mists in poorly ventilated spaces, wear a NIOSH-approved N95/P95 or CEN EN 14387 Type A-P2 / ABEK-P2 combination mist respirator.
Firefighting and Accidental Spill Response:
- Suitable Extinguishing Media: Aqueous Sodium Lactate 60 % is non-flammable and will not burn until its 40% water content has completely boiled away above 113 °C. For fires involving surrounding packaging or dried residues, extinguish with water spray, water fog, alcohol-resistant foam, dry chemical powder (ABC powder), or carbon dioxide (CO2).
- Thermal Decomposition Products: If water is evaporated in a severe fire and the anhydrous residue is heated above 200 °C to 240 °C, Sodium Lactate chars and decomposes to emit acrid smoke containing carbon monoxide (CO), carbon dioxide (CO2), organic aldehydes/lactide fumes, and sodium carbonate/oxide ash. Firefighters should wear positive-pressure Self-Contained Breathing Apparatus (SCBA).
- Spill Containment and Cleanup: Stop the leak if safe to do so and dike the spill perimeter to prevent bulk concentrated syrup from entering storm drains or surface watercourses. Because spilled Sodium Lactate 60 % creates an acute slip hazard on smooth floors, absorb the liquid with inert absorbent material (sand, vermiculite, diatomaceous earth, or spill pads), scoop into labeled salvage containers for disposal, and scrub the floor thoroughly with warm water and detergent until all slickness is removed. In the environment, Sodium Lactate 60 % is Readily Biodegradable (> 85% to 98% ultimate mineralization to CO2 and water within 5 to 14 days under OECD 301D), non-bioaccumulative (log Pow = -3.06), and practically non-toxic to fish and aquatic invertebrates (96-hour LC50 and 48-hour EC50 > 1,000 mg/L).
REGULATORY, COMPENDIAL AND ENVIRONMENTAL STATUS
Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1, EC 200-772-0 / 212-762-3, E325) holds universal regulatory, food-safety, cosmetic, and pharmacopeial approvals across major international jurisdictions:
- United States FDA (21 CFR 184.1768) & USDA-FSIS (9 CFR 424.21): Affirmed by the US FDA as Generally Recognized As Safe (GRAS) under 21 CFR 184.1768 as a direct human food ingredient (emulsifier, flavor enhancer, flavoring agent or adjuvant, humectant, and pH control agent) with no limitation other than current Good Manufacturing Practice (cGMP). Explicitly authorized by the USDA Food Safety and Inspection Service (9 CFR 424.21) as an antimicrobial agent and flavor enhancer in meat and poultry products up to 4.8% by weight of total formulation on an anhydrous sodium lactate basis (equivalent to 8.0% w/w of a 60% solution). Fully compliant with the official Food Chemicals Codex (FCC) monograph for Sodium Lactate Solution.
- European Union Food Additive Legislation (E325): Authorized across the European Union and UK under Regulation (EC) No 1333/2008 (Annex II, Group I — permitted at "quantum satis" across processed foods, bakery products, sauces, and pre-packed meat preparations) as Food Additive E 325 (Sodium lactate), with mandatory purity criteria codified in Commission Regulation (EU) No 231/2012.
- JECFA & Codex Alimentarius (INS 325): Evaluated by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) with an Acceptable Daily Intake (ADI) of "Not Limited / Not Specified" (reflecting its status as a normal human metabolic intermediate).
- Cosmetics & Personal Care Regulations (INCI: SODIUM LACTATE): Approved globally without restriction under EU Cosmetics Regulation (EC) No 1223/2009 and assessed as safe by the US Cosmetic Ingredient Review (CIR) Expert Panel (up to 10% in leave-on consumer products at formulation pH >= 3.5, and up to 30% in professional salon peels at pH >= 3.0). Approved by Ecocert, COSMOS, NaTrue, and Nordic Swan standards as a 100% bio-based, plant-fermented natural humectant and buffer.
- International Pharmacopeias (USP-NF / Ph. Eur. / BP / JP): Official monographs in the United States Pharmacopeia (USP: Sodium Lactate Solution), European Pharmacopoeia (Ph. Eur. Monograph 2115: Natrii lactatis solutio and Monograph 2116: Natrii S-lactatis solutio), British Pharmacopoeia (BP), and Japanese Pharmacopoeia (JP). Listed on the US EPA Safer Chemical Ingredients List (SCIL) with a Full Green Circle.
- Transport Classification (ADR / RID / IMDG / IATA): Not regulated as a dangerous good for road, rail, sea, or air transport (Non-Hazardous Cargo; UN Number: Not Applicable).
- Halal, Kosher, Vegan, Non-GMO, Lactose-Free, and Allergen-Free Status: Produced 100% by bacterial fermentation of plant sugars (corn, beet, cane, or tapioca) and mineral sodium alkali; completely free of milk, lactose, casein, whey, gluten, soy, nuts, and animal derivatives. Fully certified for Halal, Kosher Parve (including Passover), Vegan, Non-GMO, and Allergen-Free declarations.
FREQUENTLY ASKED QUESTIONS (FAQ)
What is Sodium Lactate 60 % (CAS 72-17-3 / 867-56-1) and why is it supplied as a 60% liquid solution instead of a dry powder?
Sodium Lactate 60 % (C3H5NaO3, anhydrous molecular weight 112.06 g/mol) is a concentrated aqueous solution containing 60.0% w/w of the monosodium salt of lactic acid dissolved in 40.0% w/w purified water (density ~1.325 g/cm3 at 20 °C, pH 6.5 to 7.5). It is supplied globally as a 60% liquid because anhydrous crystalline Sodium Lactate powder (96%–98%) is intensely deliquescent—absorbing atmospheric humidity within minutes of opening to cake into a sticky, unpumpable block and costing 3 to 4 times more to dry—whereas the 60% liquid is stable, dust-free, pumpable, and mixes instantaneously into cold meat brines, cosmetics, and soap lye.
How does E325 Sodium Lactate 60 % extend the shelf life of sausages, hams, salami, sucuk, and poultry, and how does it stop Listeria monocytogenes?
When dosed at 2.0% to 4.8% w/w in cooked or cured meat and poultry products, E325 Sodium Lactate 60 % works through two simultaneous mechanisms at neutral meat pH (pH 5.8 to 6.5): first, its hydrated Na+ and lactate ions depress internal water activity (aw) from ~0.985 down to ~0.968–0.972; second, trace undissociated lactic acid crosses bacterial cell membranes while extracellular lactate ions inhibit the bacterial enzyme lactate dehydrogenase (LDH) via mass-action feedback. When paired with 0.15% to 0.25% Sodium Diacetate (E262), it arrests Listeria monocytogenes outgrowth for 60 to 120 days of refrigerated storage while cutting cooking weight loss by 3% to 8%.
Does Sodium Lactate 60 % contain milk, dairy proteins, or lactose, and is it Vegan?
No. Despite the phonetic similarity between "lactate" and "lactose" (milk sugar), commercial Sodium Lactate 60 % is manufactured 100% by fermenting plant-derived sugars (corn starch dextrose, sugar beet, sugar cane, or tapioca) and neutralizing with mineral sodium hydroxide. It contains zero lactose, zero dairy or milk proteins, and zero animal ingredients, making it 100% Dairy-Free, Lactose-Free, Vegan, Halal, and Kosher Parve.
Why is INCI Sodium Lactate 60 % considered superior to Glycerin as a skin humectant in cosmetics?
Sodium Lactate is a core component (12% by weight) of the human skin's own Natural Moisturizing Factor (NMF) in the stratum corneum. Clinical and gravimetric studies show that Sodium Lactate binds nearly twice as much moisture as glycerin at 50% relative humidity and can increase skin moisture content by up to 84% without the sticky, tacky skin drag associated with high glycerin levels. In addition, it plasticizes corneocyte keratin directly, stimulates epidermal ceramide synthesis, and buffers AHA skin peels (at pH 3.5 to 4.5) to minimize stinging.
How is Sodium Lactate 60 % used in Cold-Process (CP) and Hot-Process (HP) bar soap making?
In Cold-Process soap making, adding 1.5% to 3.0% w/w of Sodium Lactate 60 % (typically 2% of total oil weight, or 1 teaspoon per pound of oils) into the cooled NaOH lye water hardens the saponified soap bars 2 to 3 times faster, allowing clean, dent-free unmolding in 12 to 24 hours instead of 3 to 5 days and preventing bar mushiness in the shower. In Hot-Process soap making, it keeps the cooked soap paste fluid and pourable for smooth molding and imparts a glossy, translucent finish.
How do I convert between Sodium Lactate 60 % Solution, Anhydrous Sodium Lactate, and Lactic Acid in recipes?
1.000 kg of Sodium Lactate 60 % Solution contains 600 g of anhydrous Sodium Lactate (MW 112.06 g/mol) and 400 g of water, and equals 482.3 g of 100% pure Lactic Acid (MW 90.08 g/mol) or 548.1 g of 88% Lactic Acid. Conversely, to replace 1.000 kg of dry anhydrous Sodium Lactate powder in a formula, use 1.667 kg (or 1.258 Liters at 1.325 kg/L density) of Sodium Lactate 60 % Solution and reduce the batch water by 0.667 kg.
Why did white crystals form at the bottom of my drum of Sodium Lactate 60 % during cold winter storage, and is the product spoiled?
No, the product is completely unspoiled. Stereochemically pure 60% w/w Sodium L-(+)-Lactate is a concentrated solution near its cold saturation limit; if exposed to cold winter temperatures below +5 °C to +10 °C during transit, pure Sodium Lactate crystals can slowly nucleate out of solution. Simply place the sealed drum or IBC in a warm room (25 °C to 35 °C) or use a drum warming blanket (< 50 °C) and mix gently until the crystals redissolve into a crystal-clear 60% liquid.
TECHNICAL SUMMARY AND ATAMAN KIMYA SUPPLY CAPABILITIES
Sodium Lactate 60 % (CAS 72-17-3 / CAS 867-56-1, EC 200-772-0 / 212-762-3, E325, C3H5NaO3, anhydrous MW 112.06 g/mol) stands as one of the global food, cosmetic, pharmaceutical, and chemical industries' most indispensable bio-based functional liquids—combining high active solute density (60.0% w/w active, specific gravity 1.31 to 1.34 g/cm3 at 20 °C), a neutral, protein-compatible pH (6.5 to 7.5), low water activity (aw 0.78 to 0.81), potent Listeria monocytogenes and Clostridium botulinum bacteriostasis, improved meat cooking yield and sliceability, biomimetic NMF skin hydration (+84% moisture retention), rapid cold/hot-process soap bar hardening, and USP/Ph. Eur. physiological electrolyte safety with > 95% ready biodegradability. Whether specified by meat and bakery technologists as Food Additive E325 or Lactic Acid Sodium Salt 60%, by personal care formulators and soap makers as INCI SODIUM LACTATE, or by pharmaceutical QA directors as Natrii Lactatis Solutio / Natrii S-Lactatis Solutio, consistent batch performance depends on sourcing a water-white (< 20–30 APHA), sugar-free, high-purity 60.0% w/w solution.
Ataman Kimya is a leading international supplier and distributor of Food Grade (FCC / E325 / EU 231/2012), Cosmetic Grade (INCI: SODIUM LACTATE), Pharmaceutical Grade (USP / EP / BP), and Technical Grade Sodium Lactate 60 % (Sodyum Laktat %60 / Sıvı Sodyum Laktat / Laktik Asit Sodyum Tuzu), maintaining ready stock availability in 25–30 kg HDPE jerrycans, 240–250 kg HDPE plastic drums, 1,250–1,300 kg IBC totes, and bulk road tankers. For technical specifications, batch-specific Certificate of Analysis (COA), Material Safety Data Sheet (MSDS/SDS), Halal/Kosher/Vegan/Non-GMO/Allergen-Free regulatory declarations, or competitive bulk commercial quotations on Sodium Lactate 60 % (CAS 72-17-3 / CAS 867-56-1 / E325), please contact the Ataman Kimya technical sales and international supply team directly.
Ataman Chemicals
Phone: +90 216 577 10 10
Email: info@atamankimya.com