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Sodium linoleate is the sodium salt of linoleic acid, a polyunsaturated fatty acid.
Sodium linoleate is characterized by its amphiphilic nature, possessing both hydrophilic (water-attracting) and hydrophobic (water-repelling) properties, which makes it an effective surfactant and emulsifier.
Sodium linoleate typically appears as a white to off-white powder or flakes and is soluble in water, forming a stable solution.
CAS: 822-17-3
MF: C18H33NaO2
MW: 304.45
EINECS: 212-491-0
Synonyms
12-octadecadienoicacid(z,z)-sodiumsalt;CIS-9,CIS-12-OCTADECADIENOIC ACID SODIUM SALT;LINOLEIC ACID SODIUM SALT;linoleic acid sodium;sodium (9Z,12Z)-octadeca-9,12-dienoate;(9Z,12Z)-9,12-Octadecadienoic acid sodium salt;Linoleic acid sodium salt,cis-9,cis-12-Octadecadienoic acid sodium salt;(Z,Z)-9,12-Octadecadienoic acid sodium salt
Sodium linoleate is commonly used in various applications, including cosmetics, food products, and pharmaceuticals, due to its ability to stabilize emulsions and enhance texture.
Additionally, Sodium linoleate has potential health benefits, as linoleic acid is an essential fatty acid that plays a crucial role in human nutrition.
Sodium linoleate is also known for its antioxidant properties, which can help protect cells from oxidative stress.
However, like many substances, Sodium linoleate should be handled with care, as it may cause irritation in some individuals.
Overall, sodium linoleate is valued for its functional properties in both industrial and health-related applications.
Sodium linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart.
Sodium linoleate reduces the induction of fatty acid synthetase activity in rat liver.
Sodium linoleate levels in the serum of mice with antigen-induced antibodies and allergic reactions.
Sodium linoleate attenuates gastric mucosal damage induced by ethanol, ischemia/reperfusion, and water immersion stress in a rat experimental gastric ulcer model.
Sodium linoleate significantly increases the median survival of mice inoculated with EAT cells from 18 days to 48 days, and completely inhibited tumor growth in more than 40% of mice.
Sodium linoleate makes ICR mice more sensitive to pentobarbital, as manifested by a shorter onset of anesthetic effect and a longer duration of anesthetic.
Sodium linoleate can reduce urine protein levels, plasma urea nitrogen levels, glomerular crescent formation, and fibrinoid necrosis in rats with crescent-type anti-glomerular basement membrane nephritis, while increasing the proportion of arachidonic acid (20:4n-6) in glomerular phospholipids.
Sodium linoleate is a versatile compound recognized for its significant role in various industrial and research applications.
Sodium linoleate is commonly utilized in the formulation of emulsifiers, surfactants, and stabilizers, making it invaluable in the food, cosmetic, and pharmaceutical industries.
Sodium linoleate's unique properties allow it to enhance the texture and stability of products, providing a smooth and consistent feel in creams and lotions.
Additionally, Sodium linoleate is known for its skin-conditioning benefits, making it a popular ingredient in personal care formulations aimed at moisturizing and nourishing the skin.
In research settings, sodium linoleate serves as a model compound for studying fatty acid metabolism and its effects on cell signaling pathways.
Sodium linoleate's application extends to the production of biodegradable surfactants, aligning with the growing demand for sustainable and eco-friendly alternatives in various sectors.
With its multifunctional properties and broad applicability, sodium linoleate stands out as a key ingredient for professionals seeking effective solutions in formulation and research.
Sodium linoleate Chemical Properties
Melting point: 192 °C
storage temp.: -20°C
solubility: soluble in Ethanol
form: powder to crystal
color: White to Orange to Green
biological source: plant oil (safflower)
Major Application: general analytical
life science and biopharma
Cosmetics Ingredients Functions VISCOSITY CONTROLLING
SURFACTANT - CLEANSING
SURFACTANT - EMULSIFYING
CLEANSING
InChI: 1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
InChIKey: WYPBVHPKMJYUEO-NBTZWHCOSA-M
EPA Substance Registry System:Sodium linoleate (822-17-3)
Uses
Sodium linoleate can be used for cell culture materials, fluidic device module, drug testing, and fluidic device.
Biological Activity
Sodium linoleate, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin.
The deficiency of Sodium linoleate may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants.
Sodium linoleate is used in cosmetic and personal care products.
Sodium linoleate is mainly used as emollients or moisturizers for skin, nails, and hair.
