PRODUCTS

TGIC TRIGLYCIDYL ISOCYANURATE

TGIC Triglycidyl isocyanurate is a heterocyclic polyepoxide compound with the molecular formula C12H15N3O6.
TGIC Triglycidyl isocyanurate has a white crystalline appearance and features such as corrosion resistance, high temperature resistance, chemical resistance, and light resistance.
TGIC Triglycidyl isocyanurate is widely used in powder coating formulations for exterior-grade applications because it enables durable, corrosion-resistant, and high-performance surface finishes without the release of volatile by-products.

CAS Number: 2451-62-9
EC Number: 219-514-3
Molecular Formula: C12H15N3O6
Molecular weight: 297 g/mol

Synonyms: Triglycidyl isocyanurate, 2451-62-9, 1,3,5-Triglycidyl isocyanurate, TGIC, Glycidyl isocyanurate, Tris(epoxypropyl) isocyanurate, Tri(epoxypropyl)isocyanurate, Tris(2,3-epoxypropyl)isocyanurate, XB 2615, Tris(2-epoxypropyl) isocyanurate, Tris(epoxypropyl)isocyanurate, N,N',N''-Triglycidyl isocyanurate, DTXSID4026262, 1,3,5-Triglycidyl-s-triazinetrione, NSC 296934, s-Triazine-2,4,6(1H,3H,5H)-trione, tris(2,3-epoxypropyl)-, s-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(2,3-epoxypropyl)-, DTXCID606262, 58P91Z020D, Tepic, 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(2-oxiranylmethyl)-, NSC-269934, RefChem:899627, ARALDITE PT810, 219-514-3, 1,3,5-tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione, Triglycidylisocyanurate, Tris(2,3-epoxypropyl) isocyanurate, 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(oxiranylmethyl)-, 1,3,5-Triglycidylisocyanuric acid, MFCD00080670, Isocyanuric Acid Triglycidyl Ester, 28825-96-9, TGT, MLS002703049, Triglycidyl Isocyanurate (Teroxirone), NCGC00091182-01, 1,3,5-Triglycidyl isocyanurate(Columns or Chunks or pellets), Isocyanuric Acid Tris(2,3-epoxypropyl) Ester, NSC 296964, BRN 0765833, 1,5-Triglycidyl isocyanurate, 1,5-Triglycidylisocyanuric acid, Araldite PT 810, 3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris[(2R)-oxiranylmethyl]-, rel-1, SMR001223822, CAS-2451-62-9, CCRIS 6112, HSDB 7188, EINECS 219-514-3, 1,3,5-TRIGLYCIDYLISOCYANURATE, .alpha.-triglycidyl isocyanurate, s-Triazine-2,6(1H,3H,5H)-trione, 1,3,5-tris(2,3-epoxypropyl)-, 1,3,5-tris(oxiran-2-ylmethyl)-1,3,5-triazaperhydroine-2,4,6-trione, 1,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(oxiranylmethyl)-, TGIC,Teroxirone, UNII-58P91Z020D, NSC-296964, 1,3,5-Tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, EC 219-514-3, Isocyanuric Acid (S,S,S)-Tris(2,3-epoxypropyl) Ester, SCHEMBL4932, MLS006011655, CHEMBL453863, orb1305919, orb3024983, BDBM442751, Tox21_111097, Tox21_201660, Tox21_300119, NSC296964, s2427, SBB041125, TRIS[(OXIRAN-2-YL)METHYL]-1,3,5-TRIAZINANE-2,4,6-TRIONE, Triglycidyl isocyanurate .alpha.-form, AKOS000269627, AKOS016039416, CS-W012150, FT33347, HY-W011434, NCGC00091182-02, NCGC00091182-03, NCGC00091182-04, NCGC00091182-05, NCGC00091182-06, NCGC00091182-07, NCGC00254066-01, NCGC00259209-01, AC-18356, AS-12208, NCI60_002484, ST033847, SY052501, DB-046472, I0428, NS00001196, F20307, Tris(2,3-epoxypropyl) Isocyanurate Isocyanurate, A817349, Q2453240, BRD-A39935389-001-05-9, F0777-0193, 1,3,5-Tris(2-oxiranylmethyl)-1,3,5-triazinane-2,4,6-trione #, 1,3,5-Tris[(oxiran-2-yl)methyl]-1,3,5-triazinane-2,4,6-trione, 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione,1,3,5-tris(2-oxiranylmethyl)-,homopolymer, 1,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(oxiranylmethyl)-, (.alpha.)-, 1,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(oxiranylmethyl)-, (.beta.)-

TGIC Triglycidyl isocyanurate is a trifunctional epoxy compound containing an isocyanurate ring core and three reactive glycidyl (epoxy) groups.
Due to its high functionality, TGIC Triglycidyl isocyanurate acts as an efficient crosslinking agent, particularly in carboxyl-functional polyester resin systems.

During curing, TGIC Triglycidyl isocyanurate forms a highly crosslinked three-dimensional network structure that provides excellent mechanical strength, chemical resistance, and outstanding weatherability.
TGIC Triglycidyl isocyanurate is widely used in powder coating formulations for exterior-grade applications because it enables durable, corrosion-resistant, and high-performance surface finishes without the release of volatile by-products.

TGIC Triglycidyl isocyanurate is a triazene triepoxide with antiangiogenic and antineoplastic activities.
TGIC Triglycidyl isocyanurate inhibits the growth of non-small-cell-lung cancer cells via p53 activation.

TGIC Triglycidyl isocyanurate induces cell apoptosis.
TGIC Triglycidyl isocyanurate can be used for cancer research.

TGIC Triglycidyl isocyanurate can be used as a curing agent, plastic stabilizer, and adhesive and is widely used in fields such as coatings, engineering plastics, and electronics.
Depending on the application, TGIC Triglycidyl isocyanurate can be divided into two types: industrial-grade TGIC Triglycidyl isocyanurate and electronic-grade TGIC Triglycidyl isocyanurate.

TGIC Triglycidyl isocyanurate is a coating material used in many industrial applications.
TGIC Triglycidyl isocyanurate is widely used, especially in powder coating systems.

TGIC Triglycidyl isocyanurate is a polymer with thermoset properties.
TGIC Triglycidyl isocyanurate provides high performance when used as a coating material.

TGIC Triglycidyl isocyanurate provides an excellent adhesion and provides resistance to abrasion, scratches and chemical effects.
TGIC Triglycidyl isocyanurate is also resistant to UV rays in outdoor applications, so it is preferred on surfaces that will be exposed to outdoor conditions.

TGIC Triglycidyl isocyanurate is particularly suitable for powder coating.
Powder coating is the process of spraying electrostatically charged powder particles onto a surface and then curing with heat.

TGIC Triglycidyl isocyanurate allows the powder particles to harden and form a durable coating during this process.
TGIC Triglycidyl isocyanurate acts as a curing agent.

TGIC Triglycidyl isocyanurate reacts with liquid resins during the film forming process to give hard, insoluble films.
TGIC Triglycidyl isocyanurate is used as a raw material for powder paints and coatings.

Market Demand of TGIC Triglycidyl Isocyanurate:
According to a report by the New Frontier Industry Research Center, the demand for TGIC Triglycidyl isocyanurate in China is expected to further increase in the coming years due to its wide range of applications in areas such as coatings, engineering plastics, and electronics.
In the coatings industry, TGIC Triglycidyl isocyanurate is commonly used as a curing agent for pure polyester powder coatings due to its good thermal stability and weather resistance.
In the engineering plastics industry, TGIC Triglycidyl isocyanurate can be used as a plastic stabilizer, and in the electronics industry, it can be used to produce electrical insulation materials and printed circuit boards.

The demand for TGIC Triglycidyl isocyanurate in the coatings industry is particularly high, and it is the most commonly used curing agent for powder coatings.
In recent years, the production process of TGIC Triglycidyl isocyanurate curing agents in China has been continuously optimized to reduce its irritability, and this has driven the market share of low-irritant TGIC Triglycidyl isocyanurate curing agents to increase.
With the improvement of the industry’s prosperity, the market space for TGIC Triglycidyl isocyanurate in China is expected to further expand.

Uses of TGIC Triglycidyl Isocyanurate:
TGIC Triglycidyl isocyanurate is primarily used as a highly efficient crosslinking agent in carboxyl-functional polyester powder coating systems, especially for exterior-grade applications.
TGIC Triglycidyl isocyanurate enables the formation of durable, weather-resistant, and chemically stable coatings that maintain gloss and color stability under prolonged UV exposure.
TGIC Triglycidyl isocyanurate-based formulations are widely applied in architectural aluminum profiles, automotive metal components, household appliances, industrial equipment, and protective metal structures where long-term corrosion resistance and mechanical performance are essential.

Powder Coatings:
TGIC Triglycidyl isocyanurate is used as a crosslinking agent in carboxyl-functional polyester powder coatings for exterior applications.

Architectural Coatings:
TGIC Triglycidyl isocyanurate is applied in aluminum profiles, window frames, and façade systems requiring high weather resistance.

Automotive Components:
TGIC Triglycidyl isocyanurate is used in coating of metal automotive parts exposed to outdoor conditions.

Appliance Coatings:
TGIC Triglycidyl isocyanurate provides durable and glossy finishes for white goods and household appliances.

Industrial Metal Protection:
TGIC Triglycidyl isocyanurate is applied on machinery, fences, pipelines, and steel structures for corrosion resistance.

High-Performance Protective Coatings:
TGIC Triglycidyl isocyanurate is suitable for applications requiring chemical resistance, UV stability, and long-term durability.

Industry Uses:
Not Known or Reasonably Ascertainable
Adhesion/cohesion promoter
Paint additives and coating additives not described by other categories
Monomers
Hardener
Processing aids, specific to petroleum production
Processing aids not otherwise specified

Consumer Uses:
Not Known or Reasonably Ascertainable
Paint additives and coating additives not described by other categories
Monomers
Hardener

Production and Use of TGIC Triglycidyl Isocyanurate:
TGIC Triglycidyl isocyanurate is produced from epichlorohydrin and isocyanuric acid using sodium hydrate and methanol.
No production of TGIC Triglycidyl isocyanurate occurs in Denmark.

TGIC Triglycidyl isocyanurate has been used as a curing agent for polyester resins in weather-resistant powder coatings in Europe for about 20 years.
In Denmark TGIC Triglycidyl isocyanurate has an extended use in powder coatings.

A powder coating contains up to 10 % TGIC Triglycidyl isocyanurate.
TGIC Triglycidyl isocyanurate is sprayed directly onto metal objects by an electrostatic process.

Powder coated objects include office and garden steel furniture, car parts, metal fencing, window and door frames, shelving, electrical equipment, and domestic appliances such as refrigerators, washing machines and ovens.
TGIC Triglycidyl isocyanurate is also used in electrical insulation materials, resin moulding systems, laminated sheetings, printed circuits, tools, inks, adhesives, lining materials, stabilisers for plastics and amine captures.

The alpha isomer of TGIC Triglycidyl isocyanurate was used as an experimental anti-tumour agent under the names of Teroxirone, alpha-TGT, and Henkels compound.
Clinical use of the alpha isomer was not pursued.

Applications of TGIC Triglycidyl Isocyanurate:
Triglycidal Isocyanurate is widely used as a cross-linking agent or curing agent in powder coating industry.
TGIC Triglycidyl isocyanurate is used also in the printed circuit board industry, electrical insulation and as a stabilizer in plastic industry.

Production Process of TGIC Triglycidyl Isocyanurate:
The main synthesis methods for TGIC Triglycidyl isocyanurate include epoxidation, one-step method, two-step method, and SaPSeP method.
Epoxidation mainly uses isocyanuric acid tripropyl ester as the main raw material, but its production cost is high and it has gradually been phased out by the market.

The one-step method has low product yield and high raw material consumption, making it unsuitable for large-scale production.
The two-step method involves first converting the raw material cyanuric acid into isocyanuric acid, and then using a cyclization reaction to produce the final product.
This method is the mainstream synthesis method for TGIC Triglycidyl isocyanurate and is widely used in industrial production.

TGIC Triglycidyl isocyanurate, also known as TGIC Triglycidyl isocyanurate, is produced using epichlorohydrin, cyanuric acid, and caustic soda as raw materials to synthesize (triglycidyl) isocyanurate through a two-step process.
In the first step, epichlorohydrin and cyanuric acid undergo an opening reaction under the action of a catalyst, and caustic soda is added during the reaction to promote the cyclization reaction, resulting in the formation of (triglycidyl) isocyanurate.

In the second step, the product is subjected to filtration, distillation, purification, and granulation to obtain TGIC Triglycidyl isocyanurate as the final product.
Overall, the production process of TGIC Triglycidyl isocyanurate involves opening and cyclization reactions, and it is important to carefully control the reaction conditions and purification steps to ensure the high quality and purity of the final product.

Stability and Reactivity of TGIC Triglycidyl Isocyanurate:

Chemical stability:
Stable under recommended storage conditions in dry, sealed containers.

Reactivity:
Reacts exothermically with carboxyl curing agents.
Amine curing agents.
Other nucleophilic curing agents during thermal curing.

Conditions to avoid:
Excessive heat.
Moisture.
Uncontrolled mixing with reactive hardeners.
Dust formation.

Incompatible materials:
Strong acids.
Strong bases.

Strong oxidizing agents.
Reactive amines under uncontrolled conditions.

Hazardous decomposition products:
Thermal decomposition or combustion may produce carbon oxides (CO, CO₂).
Nitrogen oxides (NOx).

Handling and Storage of TGIC Triglycidyl Isocyanurate:

Handling:
Avoid generation and inhalation of dust.
Prevent skin and eye contact.

Use adequate ventilation.
Follow good industrial hygiene practices.

Storage:
Store in a cool, dry, well-ventilated area away from moisture and direct sunlight.
Keep containers tightly closed when not in use.

Storage conditions:
Protect from humidity.
Protect from elevated temperatures to prevent caking or premature reaction.

First Aid Measures of TGIC Triglycidyl Isocyanurate:

Inhalation:
Move the affected person to fresh air.
Seek medical attention if irritation or respiratory symptoms persist.

Skin contact:
Wash thoroughly with soap and water.
Remove contaminated clothing.

Eye contact:
Rinse cautiously with water for at least 15 minutes.
Seek medical advice if irritation continues.

Ingestion:
Rinse mouth.
Do not induce vomiting.
Obtain medical attention if necessary.

Firefighting Measures of TGIC Triglycidyl Isocyanurate:

Suitable extinguishing media:
Water spray.
Foam.

Dry chemical powder.
Carbon dioxide (CO₂).

Specific hazards:
Burning may release toxic and irritating fumes including carbon oxides.
Nitrogen oxides.

Protective equipment:
Firefighters should wear self-contained breathing apparatus.
Protective clothing.

Accidental Release Measures of TGIC Triglycidyl Isocyanurate:

Personal precautions:
Avoid dust formation.
Use appropriate personal protective equipment.
Ensure adequate ventilation.

Environmental precautions:
Prevent material from entering drains or waterways.

Methods for cleaning up:
Collect mechanically using non-sparking tools.
Place in suitable containers for disposal.
Avoid generating airborne dust.

Exposure Controls / Personal Protection of TGIC Triglycidyl Isocyanurate:

Respiratory protection:
Use approved dust respirator (P2 or P3) if ventilation is insufficient.

Hand protection:
Wear chemical-resistant gloves.

Eye protection:
Safety goggles or face shield recommended.

Skin protection:
Wear protective clothing to minimize skin exposure.

Identifiers of TGIC Triglycidyl Isocyanurate:
Molecular Formula: C12H15N3O6
Molecular weight: 297
CAS Number: 2451-62-9
EINECS Number: 219-514-3
UN Number: 2811

Empirical Formula (Hill Notation): C12H15N3O6
CAS Number: 2451-62-9
Molecular Weight: 297.26
NACRES: NA.23
PubChem Substance ID: 24863665
UNSPSC Code: 12162002
EC Number: 219-514-3
MDL number: MFCD00080670

CAS Number: 2451-62-9
Purity: 98.0
Molecular Formula: C12H15N3O6
Molecular Weight: 297.26

InChI key: OUPZKGBUJRBPGC-UHFFFAOYSA-N
InChI: 1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2
SMILES string: O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4
form: powder
Quality Level: 200

Properties of TGIC Triglycidyl Isocyanurate:
Appearance: White powder or granules
Boiling Point, °C: >240 (decomposes)
Density, g/cm3: 1.42
Flash Point, °C: 170
Melting point, °C: 95
Molecular weight, g/mol: 297.26
Odor: Odorless
Purity, %: 99
Refractive index, n20/D: 1.5290

Molecular Weight: 297.26 g/mol
XLogP3-AA: -1.5
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 6
Exact Mass: 297.09608521 Da
Monoisotopic Mass: 297.09608521 Da
Topological Polar Surface Area: 98.5 Å²
Heavy Atom Count: 21
Complexity: 416
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 3
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of TGIC Triglycidyl Isocyanurate:
Appearance: White granule
Epoxy equivalent: < 105
Viscosity (at 120℃): < 100CP
Epichlorohydrin: < 100ppm
Volatile Matter: < 1.0%
Chlorine: < 0.55%
Melting range: 95～115℃