PRODUCTS

TIHOUREA

DESCRIPTION:

Thiourea is highly reactive and can be used to prepare various compounds.
Thiourea can react with a variety of oxidants to form organic compounds, and can also react with inorganic compounds to make soluble addition compounds.
Thiourea is an organosulfur compound with the formula SC(NH2)2 and the structure H2N−C(=S)−NH2.

CAS NUMBER: 62-56-6

EC NUMBER: 200-543-5

MOLECULAR FORMULA: CH4N2S

MOLECULAR WEIGHT: 76.12

Thiourea is structurally similar to urea (H2N−C(=O)−NH2), except that the oxygen atom is replaced by a sulfur atom (as implied by the thio- prefix); however, the properties of urea and thiourea differ significantly.
Thiourea is the simplest member of the thiourea class, which consists of urea in which the oxygen atom has been replaced by sulfur.
Thiourea has a chromophore and antioxidant function.
Thiourea is a member of ureas, a member of thioureas and a one-carbon compound.

Thiourea is derived from a carbonothioic O, O-acid and a urea.
Thiourea is a reagent in organic synthesis.
Thiourea refers to a broad class of compounds with the general structure R2N−C(=S)−NR2.
Thioureas are related to thioamides, e.g. RC(S)NR2, where R is methyl, ethyl, etc.

Thiourea is a white crystalline solid, both naturally occurring and synthetic, that is soluble in water, ammonium thiocyanate solution and ethanol.
In the past, Thiourea was used as a photographic toning agent, a component of hair preparations and a dry cleaning agent.
Currently, Thiourea is only used in animal glue liquefiers and silver tarnish removers.
When heated to decomposition, thiourea emits toxic fumes of nitrogen oxides and sulfur oxides.
Long-term exposure of humans to thiourea may cause bone marrow damage, resulting in reduced levels of red blood cells, white blood cells and/or platelets.

Thiourea is reasonably anticipated to be a human carcinogen.
Thiourea appears as white or off-white crystals or powder.
Thiourea is an organic compound of carbon, nitrogen, sulfur and hydrogen, with the formula CSN2H4 or (NH2)2CS.
Thiourea is similar to urea, except that the oxygen atom is replaced by a sulfur atom.
The properties of urea and thiourea differ significantly because of the relative electronegativities of sulfur and oxygen.

Thiourea is a versatile reagent in organic synthesis.
Thioureas are related to thioamides, e.g. RC(S)NR2, where R is methyl, ethyl, etc.
Thiourea is prohibited from use in food.
Industrial uses of thiourea include production of flame retardant resins, and vulcanization accelerators.

Thiourea is used as an auxiliary agent in diazo paper (light-sensitive photocopy paper) and almost all other types of copy paper.
Thiourea is also used to tone silver-gelatin photographic prints.
The liquid silver cleaning product TarnX is essentially a solution of thiourea.
A leaching agent for gold leaching and silver leaching can be created by selectively oxidizing thiourea, bypassing the steps of cyanide use and smelting. Another common application for use of thiourea is a common sulfur source for making semiconductor cadmium sulfide nanoparticle.

Thiourea is a planar molecule.
The C=S bond distance is 1.60±0.1 for a wide range of derivatives.
This narrow range indicates that the C=S bond is insensitive to the nature of the substitutent.
Thus, the thioamide, which is similar to an amide group, is difficult to perturb.
Thiourea reduces peroxides to the corresponding diols.

The intermediate of the reaction is an unstable epidioxide which can only be identified at -100 °C.
Epidioxide is similar to epoxide except with two oxygen atoms.
This intermediate reduces to diol by thiourea.
Thiourea has been shown to exhibit anti-viral, anti-fungal and radical scavenger functions.
Thiourea is an analogue of urea containing sulphur.

Thiourea appears as white or off-white crystals or powder.
Thiourea sinks and mixes with water.
Thiourea is odorless and has a bitter taste.
Thiourea is used for its synthetic equivalence to hydrogen sulphide.
Thiourea plays an important role in the construction of heterocycles.

Thiourea appears as white crystals, which are combustible and, in contact with fire give off irritating or toxic fumes.
Thiourea acts as a precursor to sulphide to produce metal sulphides like mercury sulphide.
Thiourea reacts with alkyl halides and gives isothiouronium salt on further hydrolysis reaction of this salt results in the formation of thiol and urea.
Thiourea is used in industries for the production of flame retardant resins and vulcanisation accelerators.
Thiourea is used as a chemical intermediate or catalyst in metal processing and plating and in photo processing.

Thiourea is used as a contaminant in the ethylene bisdithiocarbanate fungicides and can also be formed when food containing the fungicides is cooked.
Its chemical formula is SC(NH2)2. As the name and its composition suggest, thiourea is very much similar to urea.
In thiourea, the oxygen atom of urea is displaced by the sulfur atom.
Thiourea, also known as thiocarbamide, is an organic molecule that is similar to urea (q.v.) but includes sulphur rather than oxygen; its chemical formula is CS(NH2)2, whereas ureas are CO(NH2)2.

Thiourea is made by inducing a chemically similar substance to undergo rearrangement, such as heating ammonium thiocyanate (NH4SCN).
The addition of hydrogen sulphide to cyanamide is a more regularly utilised technique of production.
Thiourea contains a lot of the same chemical features as urea, although it's not as widely used.
The little amount of thiourea consumed is mostly used in photography as a fixing agent, in the production of thermosetting resin, as an insecticide, in the treatment of textiles, and as a starting ingredient for some colours and pharmaceuticals.
At 182° C (360° F), thiourea crystallises as colourless crystals.

Thiourea is poisonous, albeit the lethal dose has not been determined.
Thiourea is a bitter-tasting white water-soluble crystalline chemical that forms additional compounds with metal ions and is utilised in photographic fixing, rubber vulcanization, and synthetic resin production.
The sulphur analogue of urea is thiourea.
Thiourea is employed because of its chemical resemblance to hydrogen sulphide.

Thiourea plays a crucial function in the creation of heterocycles.
Thiourea looks like white crystals that are flammable and emit unpleasant or poisonous odours when exposed to fire.
Thiourea serves as a precursor to sulphide, allowing metal sulphides such as mercury sulphide to form.
Exposure to thiourea has negative health consequences and can lead to poisoning.
Thiourea enters the body by inhalation of its aerosol and ingestion.

Thiourea is known to produce skin sensitization and a variety of thyroid health problems when exposed to it repeatedly or for an extended period of time.
Thiourea is used in the manufacturing of flame retardant resins and vulcanization accelerators, among other things.
Thiourea is utilised as an auxiliary agent in the diazo paper and nearly all other types of copy paper.
Thiourea is also used to colour silver-gelatin photography prints.
Thiourea dioxide is a thiourea oxidising chemical that is stable in solid form and cold aqueous solution.
Thiourea exhibits a moderate acidic reaction and only achieves maximal reduction capacity in an aqueous solution when heated to around 100 ° C.

Thiourea is an organic compound of carbon, nitrogen, sulfur and hydrogen, with the formula CSN2H4 or (NH2)2CS.
Thiourea is similar to urea, except that the oxygen atom is replaced by a sulfur atom.
The properties of urea and thiourea differ significantly because of the relative electronegativities of sulfur and oxygen.
Thioureas are related to thioamides, e.g. RC(S)NR2, where R is methyl, ethyl, etc.

Thiourea is prohibited from use in food.
Industrial uses of thiourea include production of flame retardant resins, and vulcanization accelerators.
Thiourea is used as an auxiliary agent in diazo paper and almost all other types of copy paper.
Thiourea is also used to tone silver-gelatin photographic prints.
The liquid silver cleaning product TarnX is essentially a solution of thiourea.

Thiourea is a derivative of the biological compound, urea.
Thiourea can be used as a denaturant in lysis buffers and similar sample buffers that require solubilization of proteins.
Thiourea can act as an antioxidant and chromophore.
Thiourea can be used in the study of cellular redox, autophagy, and aging.
Thiourea is an organosulfur compound with the formula SC(NH2)2.

Thiourea is structurally similar to urea, except that the oxygen atom is replaced by a sulfur atom, thus the properties of urea and thiourea differ significantly.
Thiourea is a colorless white solid, soluble in water.
Thiourea is odorless and has a taste, often described as bitter.
Thiourea sublimes under vacuum between 150-160 °C.
Thiourea appears as white crystal/powder, is combustible, and on contact with fire, gives off irritating or toxic fumes/gases.

Thiourea is a reducing agent used primarily in the production of bleached recycled pulp.
In addition, Thiourea is also effective in the bleaching of stone groundwood, pressurised groundwood.
Thiourea undergoes decomposition on heating and produces toxic fumes of nitrogen oxides and sulphur oxides.
Thiourea reacts violently with acrolein, strong acids, and strong oxidants.
The main application of thiourea is in textile processing and also is commonly employed as a source of sulphide.

Thiourea is a precursor to sulphide to produce metal sulphides, for example, mercury sulphide, upon reaction with the metal salt in aqueous solution.
The industrial uses of thiourea include production of flame-retardant resins and vulcanisation accelerators.
Thiourea is used as an auxiliary agent in diazo paper, light-sensitive photocopy paper, and almost all other types of copy paper.
Thiourea is used in many industrial applications, including as a chemical intermediate or catalyst, in metal processing and plating, and in photoprocessing.

USES:

The most common uses for thiourea have been for the production of thiourea dioxide (30%), in leaching of gold and silver ores (25%), in diazo papers (15%), and as a catalyst in the synthesis of fumaric acid.
Thiourea has also been used in the production and modification of synthetic resins.
Other uses of thiourea are as a photographic toning agent, in hair preparations, as a drycleaning agent, in the synthesis of pharmaceuticals and pesticides, in boiler-water treatment, and as a reagent for bismuth and selenite ions.

Thiourea has also been used in textile and dyeing auxiliaries, in the production of industrial cleaning agents, for engraving metal surfaces, as an isomerization catalyst in the conversion of maleic to fumaric acid, in copper-refining electrolysis, in electroplating, and as an antioxidant. Other uses have included as a vulcanization accelerator, an additive for slurry explosives,as a viscosity stabilizer for polymer solutions, and as a mobility buffer in petroleum extraction.
Thiourea is also used as an ingredient of consumer silver polishes, and has been used in the removal of mercury from wastewater by chlorine-alkali electrolysis

Thiourea is a sulphur analogue of urea.
Thiourea is a crystalline and colorless solid which is relatively insoluble in water.
Thiourea, capable of breaking the dormancy of seeds, is used to stimulate seed germination.

APPLICATION:

-Thiourea is the raw material for the synthesis of drugs,such as sulfathiazole, methionine and pig slices.
-Thiourea is used as raw materials for dyes and dyeing auxiliaries, resins and press-plastic powder.
-Thiourea can also be used as a vulcanization accelerator for rubber, a flotation agent for metal minerals, a catalyst for making phthalic anhydride and fumaric acid, as a metal corrosion inhibitor.
-Thiourea in photographic materials,itcan be used as developer and toner.
-Thiourea can also be used in electroplating industry.
-Thiourea is also used in diazo photosensitive paper, synthetic resin coating, anion exchange resin, germination accelerator, fungicides and many other aspects.
-Thiourea is also used as a fertilizer.
-Thiourea is used in the manufacture of drugs, dyes, resins, press-plastic powder, rubber vulcanization accelerator, metal mineral flotation agent and other raw materials.

APPLICATION AREAS:

-Thiourea is used in the following products: laboratory chemicals and water softeners.
-Thiourea is used in the following areas: scientific research and development.
-Thiourea of this substance into the environment are likely to occur: indoor use as a reagent and outdoor use as a reagent.

USAGE AREAS:

-optics
-electronics
-new energy materials

APPLICATION:

-Thiox precursor:

Thiourea per se has few applications.
Thiourea is mainly consumed as a precursor to thiourea dioxide, which is a common reducing agent in textile processing.

-Fertilizers:

Recently thiourea has been investigated for its multiple desirable properties as a fertilizer especially under conditions of environmental stress.
Thiourea may be applied in various capacities, such as a seed pretreatment (for priming), foliar spray or medium supplementation.

-Other uses:

Other industrial uses of thiourea include production of flame retardant resins, and vulcanization accelerators.
Thiourea is used as an auxiliary agent in diazo paper, light-sensitive photocopy paper and almost all other types of copy paper.
Thiourea is also used to tone silver-gelatin photographic prints.
Thiourea is used in the Clifton-Phillips and Beaver bright and semi-bright electroplating processes.
Thiourea is also used in a solution with tin(II) chloride as an electroless tin plating solution for copper printed circuit boards.

USAGE AREAS:

Thiourea has been used:

-as a component of lysis buffer for liver tissue homogenization
-in 2-D sample buffer for two-dimensional in-gel protein tyrosine phosphatases (PTP) assay
-in rehydration buffer for protein extraction

PROPERTIES:

-Molecular weight: 76.12
-Melting point: 171 °C
-Boiling point: 263.89 °C(estimate)
-Density: 1.41g/cm3
-appearance: White crystal powder.

PHYSICAL AND CHEMICAL ACTIONS:

Thiourea is a free radical scavenger of the peroxide radical.
Thiourea is also known to be used in the treatment of hyperthyroidism.

STRUCTURE AND BONDING:

Thiourea is a planar molecule. The C=S bond distance is 1.71 Å.
The C-N distances average 1.33 Å.
The weakening of the C-S bond by C-N pi-bonding is indicated by the short C=S bond in thiobenzophenone, which is 1.63 Å.
Thiourea occurs in two tautomeric forms, of which the thione form predominates in aqueous solutions.
The equilibrium constant has been calculated as Keq is 1.04×10−3.
The thiol form, which is also known as an isothiourea, can be encountered in substituted compounds such as isothiouronium salts.

PRODUCTION:

The global annual production of thiourea is around 10,000 tonnes.
About 40% is produced in Germany, another 40% in China, and 20% in Japan.
Thiourea can be produced from ammonium thiocyanate, but more commonly it is produced by the reaction of hydrogen sulfide with calcium cyanamide in the presence of carbon dioxide.

PRODUCT INFORMATION:

-CAS number: 62-56-6
-EC index number: 612-082-00-0
-EC number: 200-543-5
-Hill Formula: CH₄N₂S
-Chemical formula: H₂NCSNH₂
-Molar Mass: 76.12 g/mol
-HS Code: 2930 90 98

PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 1.405 g/cm3 (20 °C)
-Ignition temperature: 440 °C Dust
-Melting Point: 176 - 178 °C
-pH value: 5.0 - 7 (50 g/l, H₂O, 20 °C)
-Bulk density: 640 kg/m3
-Solubility: 137 g/l

SPECIFICATION:

-Assay: ≥ 99.0 %
-Appearance of solution (50 g/l; water): Clear to almost clear and colorless.
-Melting point: 174 - 178 °C
-Fe (Iron): ≤ 0.0005 %
-Sulfated ash (600 °C): ≤ 0.1 %
-Loss on Drying (105°C): ≤ 0.5 %

PROPERTIES:

-Molecular Weight: 76.12
-XLogP3-AA: -0.8
-Hydrogen Bond Donor Count: 2
-Hydrogen Bond Acceptor Count: 1
-Rotatable Bond Count: 0
-Exact Mass: 76.00951931
-Monoisotopic Mass: 76.00951931
-Topological Polar Surface Area: 84.1 Å²
-Heavy Atom Count: 4
-Complexity: 29
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes

SPECIFICATION:

-Assay: ≥99.0%
-ign. residue: ≤0.1% (as SO4)
-loss: ≤0.5% loss on drying, 105°C, 2h
-mp: 170-176 °C (lit.), 174-177 °C
-solubility: H2O: passes test

CHEMICAL INFORMATION:

-CH4N2S: Thiourea
-Density: 1.4 g/cm³
-Molecular Weight/ Molar Mass: 76.12 g/mol
-Boiling Point: 150 – 160oC
-Melting Point: 176 – 178oC
-Chemical Formula: CS(NH2)2

PHYSICAL INFORMATION:

-Odour: odourless
-Appearance: White solid
-pH: > 3
-Surface tension: 1.0404 X 10-2 N/m
-Solubility: soluble in water (137 g/litre at 20 °C)

STORAGE:

Store at +15°C to +25°C.
Warehouse should be ventilated, low temperature, dry.
Store separately from oxidants, acids and bases.

SYNONYM:

Thiocarbamide
62-56-6
2-Thiourea
Isothiourea
Pseudothiourea
Sulfourea
Sulourea
Thiuronium
2-Thiopseudourea
Thiocarbonic acid diamide
Carbamimidothioic acid
Urea, thio-
beta-Thiopseudourea
Thiomocovina
Urea, 2-thio-
Tsizp 3
Pseudourea, 2-thio-
Thiocarbamid
Thioharnstoff
Thiokarbamid
Sulfouren
USAF EK-497
RCRA waste number U219
carbonothioic diamide
thio-urea
NSC 5033
17356-08-0
.beta.-Thiopseudourea
GYV9AM2QAG
MFCD00008067
H2NC(S)NH2
(NH2)2CS
CHEMBL260876
DTXSID9021348
CHEBI:36946
NSC-5033
TOU
DTXCID101348
Thiomocovina
Caswell No. 855
sulfocarbamide
RCRA waste no. U219
CAS-62-56-6
53754-90-8
CCRIS 588
S C (N H2)2
HSDB 1401
THIOUREA, ACS
UNII-GYV9AM2QAG
EINECS 200-543-5
EPA Pesticide Chemical Code 080201
aminothioamide
thiopseudourea
AI3-03582
aminothiocarboxamide
2-Thio-PseudoureaThiocarbonic diamide
2-Thio-Ure
beta -thiopseudourea
THIOUREA
THIOUREA
THIOUREA
WLN: ZYZUS
THIOUREA
THIOUREA
Urea, thio-
THIOUREA [WHO-DD
EC 200-543-5
Thiourea ACS Reagent Grade
Thiourea, LR, >=98%
MLS002454451
BIDD:ER0582
NSC5033
HMS2234E12
HMS3369M21
AMY40190
BCP27948
STR00054
ZINC8437745
Thiocarbamide,Isothiourea,2-Thiourea
Tox21_201873
Tox21_302767
BDBM50229993
STL194300
Thiourea, ACS reagent, >=99.0%
AKOS000269032
AKOS028109302
CCG-207963
UN 2877
Thiourea, ReagentPlus(R), >=99.0%
NCGC00091199-01
NCGC00091199-02
NCGC00091199-03
NCGC00256530-01
NCGC00259422-01
Thiourea, >=99.999%
BP-31025
SMR000857187
Thiourea, JIS special grade, >=98.0%
Thiourea, p.a., ACS reagent, 99.0%
FT-0675198
T0445
T2475
T2835EN300-19634
T-3650
PROPYLTHIOURACIL IMPURITY A
10.14272/UMGDCJDMYOKAJW-UHFFFAOYSA-N.
A833853
Q528995
Thiourea, puriss. p.a., ACS reagent, >=99.0%
doi:10.14272/UMGDCJDMYOKAJW-UHFFFAOYSA-N.1
J-524966
F0001-1650

IUPAC NAME:

Thiocarbamide
thiocarbamide
Thioharnstoff
THIOUREA
hiourea
thiourea
Thiourea
thiourea
thiourea; thiocarbamide
Tiourea
Urea, 2-thio-

TRADE NAME:

Thiocarbamide
Thioharnstoff
Thioreum
Thiourea
Urea, 2-thio-