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Uncaria rhynchophylla extract is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities).
Uncaria rhynchophylla extract value can be found on the certificate.
Uncaria rhynchophylla extract is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
CAS: 906-33-2
MF: C16H18O9
MW: 354.31
EINECS: 212-997-1
Synonyms
;[1R-(1alpha,3alpha,4alpha,5beta)]-3-[[3-(3,4-dihydroxyphenyl)-1-oxoallyl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid;Neochlorogenic acid;5-O-CAFFEOYLQUINICACID;;(1R,3R,4S,5R)-5-[(E)-3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy-1,3,4-trihydroxycyclohexane-1-carboxylic acid;5-Caffeoylquinic acid;trans-5-O-Caffeoyl-D-quinate;Neochlorogenic acid，5-;Caffeoylquinic acid，trans-5-O-Caffeoyl-D-quinate;(1R)-3β-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-;propenyl]oxy]-1β,4β,5α-trihydroxycyclohexane-1α-carboxylic acid;Neochlorogenic acid;906-33-2;Neochlorogenate;(E)-Neochlorogenic Acid;5-Caffeylquinic acid;UNII-O4601UER1Z;O4601UER1Z
;(1R,3R,4S,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid;5-Caffeoylquinic acid;CHEBI:16384;5-O-Caffeoylquinic acid;trans-Neochlorogenic acid;EINECS 212-997-1;MFCD10566639;5-O-(trans-3,4-Dihydroxycinnamoyl)-D-quinic acid;3-CQA;CHEMBL249450;trans-5-O-caffeoyl-D-quinic acid;trans-5-O-Caffeoylquinic acid;3-O-(E)-CAFFEOYLQUINIC ACID;Cyclohexanecarboxylic acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)-1,4,5-trihydroxy-, (1R-(1alpha,3alpha,4alpha,5beta))-
trans-5-O-caffeoyl-D-quinate;(1R,3R,4S,5R)-3-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexanecarboxylic acid;1D-[1(OH),3,4/5]-3-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,4,5-trihydroxycyclohexanecarboxylic acid;342811-68-1;CYCLOHEXANECARBOXYLIC ACID, 3-(((2E)-3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPEN-1-YL)OXY)-1,4,5-TRIHYDROXY-, (1R,3R,4S,5R)-;Cyclohexanecarboxylic acid,3-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,(1R,3R,4S,5R)-;5-O-caffeoyl quinic acid;Nochlorogenic acid;neochlorogenic_acid;Neochlorogenic-acid;Quinic acid, 5-caffeoyl-, E-;SCHEMBL13567302;SCHEMBL18317299;ACon1_000392;CWVRJTMFETXNAD-NXLLHMKUSA-N;DTXSID301347903;HMS3886H18;HY-N0722;BDBM50163308;s9136;AKOS015901853;AC-6061;CCG-268077;CS-3770;Neochlorogenic acid, analytical standard;NCGC00169121-01;NCGC00169121-02;(1R,3R,4S,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexanecarboxylic acid;AS-75008;DA-66022;N1155;NS00097276;C17147;Q-100887;Q6992128;656B3E48-4F1F-4FC8-A3B2-B0FADAB84AF5;NEOCHLOROGENIC ACID (CONSTITUENT OF ST. JOHN'S WORT);Neochlorogenic acid, from Lonicera japonica, >=98.0% (HPLC);NEOCHLOROGENIC ACID (CONSTITUENT OF ST. JOHN'S WORT) [DSC];(1R,3R,4S,5R)-3-((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4,5-trihydroxycyclohexane-1-carboxylic acid;(1R,3R,4S,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid;(1R-(1.ALPHA.,3.ALPHA.,4.ALPHA.,5.BETA.))-3-((3-(3,4-DIHYDROXYPHENYL)-1-OXOALLYL)OXY)-1,4,5-TRIHYDROXYCYCLOHEXANECARBOXYLIC ACID;(1R-(1alpha,3alpha,4alpha,5beta))-3-((3-(3,4-Dihydroxyphenyl)-1-oxoallyl)oxy)-1,4,5-trihydroxycyclohexanecarboxylic acid;[1R - (1alpha,3alpha,4alpha,5beta )] - 3 - [[3 - (3,4 - dihydroxyphenyl) - 1 - oxoallyl]oxy] - 1,4,5 - trihydroxycyclohexanecarboxylic acid;CYCLOHEXANECARBOXYLIC ACID, 3-((3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY)-1,4,5-TRIHYDROXY-, (1R-(1.ALPHA.,3.ALPHA.(E),4.ALPHA.,5.BETA.))-;CYCLOHEXANECARBOXYLIC ACID, 3-((3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY)-1,4,5-TRIHYDROXY-, (1R-(1.ALPHA.,3.ALPHA.,4.ALPHA.,5.BETA.))-;CYCLOHEXANECARBOXYLIC ACID, 3-((3-(3,4-DIHYDROXYPHENYL)-1-OXO-2-PROPENYL)OXY)-1,4,5-TRIHYDROXY-, (1R-(1alpha,3alpha(E),4alpha,5beta))-
A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 5-hydroxy group of quinic acid.
Uncaria rhynchophylla extract is a polyphenol that may be found in plants.
Uncaria rhynchophylla extract has been shown to inhibit the proliferation of cancer cells and human gastrointestinal cells, inhibit the expression of proinflammatory mediators, and reduce oxidative stress.
Uncaria rhynchophylla extract also has anti-inflammatory activities and can be used for the treatment of brain disease.
Uncaria rhynchophylla extract binds to DNA and inhibits transcription by binding to response elements on DNA.
This polyphenol also inhibits x-ray diffraction, which is an experimental method for studying crystal structures of materials.
Uncaria rhynchophylla extract is a cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 5-hydroxy group of quinic acid.
Uncaria rhynchophylla extract has a role as a plant metabolite.
Uncaria rhynchophylla extract is a cyclitol carboxylic acid and a cinnamate ester.
Uncaria rhynchophylla extract is functionally related to a (-)-quinic acid and a trans-caffeic acid.
Uncaria rhynchophylla extract is a conjugate acid of a trans-5-O-caffeoyl-D-quinate.
Uncaria rhynchophylla extract Chemical Properties
Melting point: 204-206 °C (decomp)
Boiling point: 665.0±55.0 °C(Predicted)
Density: 1.65±0.1 g/cm3(Predicted)
Storage temp.: 2-8°C
Solubility: DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated)
Form: Solid
pka: 3.90±0.50(Predicted)
Color: White to Off-White
Stability: Hygroscopic
InChIKey: CWVRJTMFETXNAD-NXLLHMKUSA-N
LogP: 0.370 (est)
CAS DataBase Reference: 906-33-2
Biochem/physiol Actions
Uncaria rhynchophylla extract has been found to have an inhibitory effect on the biosynthesis of melanin.
Therefore Uncaria rhynchophylla extract can be used on harvested fruits to prevent brown rot infection caused by?Monilinia laxa.
Uncaria rhynchophylla extract also shows impressive antioxidant, antibacterial, antiviral and antipyretic characteristics.
Uncaria rhynchophylla extract has the potential to be used in the management of acute and chronic inflammatory diseases due to its anti-inflammatory activity.
Uncaria rhynchophylla extract may function as chemopreventive compounds due to growth inhibition seen in breast cancer cell line MDA-MB-435.
