BUTYLHYDROXYANISOLE (BHA)

Butylhydroxyanisole
Butylhydroxyanisole (E320)
Butylated hydroxyanisole

name    mixture of 2- tert - butyl-4- hydroxyanisole and 3- tert - butyl-4- hydroxyanisole
Abbreviations: BHA
Chem. formula: C11 H16 O2
Physical properties
condition: wax-like solid
Molar mass: 180.24 g / mol
Density:1.0587 g / cm³
Thermal properties
Temperature
 •  melting: 48-55 ° C
 •  boiling: 264-270 ° C
Chemical properties
Solubility
 • in water: 0 g / 100 ml
Optical properties
Refractive index: 1.5303
Classification
Reg. CAS number: 25013-16-5
PubChem    24667
Reg. EINECS number: 246-563-8
Codex Alimentarius    E320
ChEBI    76359
Data are based on standard conditions (25 ° C, 100 kPa) unless otherwise noted.
Butylhydroxyanisole (E320) - solid wax-like substance is a mixture of isomers - 2- tert -butyl-4-hydroxyanisole and 3- tert -butyl-4-hydroxyanisole. It is synthesized from 
4-methoxyphenol and isobutylene . It is used as an antioxidant and preservative in food products, animal feed, cosmetics, rubber, oil products

Butylhydroxyanisole
Name:    Butylhydroxyanisole
A type:    Food supplement
Category:    Antioxidants
Group description:    Antioxidants - additives with an index (E-300 - E-399) protect food from oxidation, rancidity and discoloration. They are both natural compounds (ascorbic acid, vitamin E), and chemically synthesized, non-naturally occurring compounds. They are added to fat and oil emulsions (for example, mayonnaise).
Food additive laws and documents:
Permitted use - 4
Mentions about the supplement - 5
Application of the additive by country:
Russia - allowed
Ukraine - allowed
Belarus - allowed
European Union - allowed
USA - allowed
Canada - Allowed
View documents
Description of food additive
E-320 Butylhydroxyanisole - food additive, antioxidant, antioxidant.
Characteristic:
Butylhydroxyanisole E-320 is a food additive used as an antioxidant (protects food from oxidation), and also helps to preserve their color, odor and taste (does not allow them to taste bitter). The chemical name of the additive is butylhydroxyanisole , molecular formula: C11H16O2. The abbreviation BHA (from English butylated hydroxyanisole ) is often used . Additive E-320- consists of several organic compounds that are isomers in relation to each other: 2 - tert-butyl-4-hydroxyanisole and 3 - tert-butyl-4-hydroxyanisole. This additive is made from isobutylene and 4-methoxyphenol. By its physical properties, the food additive has a solid, waxy aggregate state, does not dissolve in water, but dissolves in organic weakly polar and non-polar solvents: methanol, ethanol , oils and fats. Externally, the E-320 additive can have a white, pinkish or white-yellowish color, it also has a weak characteristic odor.

Application:
By adding Butylhydroxyanisole to food, you can significantly increase their shelf life. Regardless of the amount of the additive, its properties do not change. Therefore, a sufficient dose of E-320 for the protection of rendered and culinary fats, as well as fats of animal origin, during their heat treatment is 0.01-0.02%. If you need to enhance its synergistic properties, add other antioxidantssuch as citric acid or phosphoric acid. The food additive can be a constituent in beef, lamb, fish, poultry oils and oils that are used in high temperature cooking. It is also added to dried meat, dry mixes, dry cereal breakfasts, broth and soup concentrates, spices, sauces, nuts, confectionery and chewing gums. E-320 is widely used as an antioxidant and preservative:

in food products;
in the impregnation of packages with products that contain fats;
in animal feed;
as an antioxidant for pharmaceuticals;
in cosmetics;
in rubber and petroleum products;
to stabilize industrial oils, waxes and fats.
Effects on the human body:
The maximum permissible daily dose per day is 0.5 mg / kg of human weight. Having studied the chemical composition and properties of the food antioxidant E-320 , scientists came to the 
conclusion that the food additive is “conditionally safe” for human life and health. Since, basically, a person does not exceed daily doses in his consumption that can adversely affect
health. But medicine is of the opinion that E-320, interacting with nitrates, is a carcinogen and exhibits mutagenic properties, changing DNA cells. However, research is currently
 underway on the supplement to ensure that it does help slow the growth of cancerous tumors and prevent HIV disease and the development of the herpes virus. Antioxidant E-320 is 
included in the list of approved food additives in the European Union, Ukraine and the Russian Federation.

2-tert-Butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol (mixture)
Other names
2-tert-Butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole (mixture)
BOA
BHA
tert-Butyl-4-hydroxyanisole
(1,1-Dimethylethyl)-4-methoxyphenol
tert-Butyl-4-methoxyphenol
Antioxyne B[1]
Butylated hydroxyanisole
25013-16-5 
8003-24-5 
9009-68-1 
121-00-6 
88-32-4 
Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. It is prepared from 4-methoxyphenol and isobutylene. It is a waxy solid used as a food additive with the E number E320. The primary use for BHA is as an antioxidant and preservative in food, food packaging, animal feed, cosmetics, rubber, and petroleum products.[3] BHA also is commonly used in medicines, such as isotretinoin, lovastatin, and simvastatin, among others.