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Calcium acetate, also known as acetate of lime or vinegar salts, is the calcium salt of acetic acid.
Calcium acetate is an odorless powder.
Calcium acetate has an important role in the nutrition of humans and animals.
CAS: 62-54-4
MF: C4H6CaO4
MW: 158.17
EINECS: 200-540-9
Synonyms
acetatedecalcium;Aceticacid,calciunsalt;teltozan;vinegarsalts;CALCIUM ACETATE EXTRA PURE, FCC, E 263;CALCIUM ACETATE HYDRATE PURE;CALCIUM ACETATE HYDRATE, 99.99%;CALCIUM ACETATE SIGMAULTRA
Hormonal mechanisms control absorption of dietary calcium (including added calcium salts) allowing adaptation to a range of calcium intakes while maintaining a relatively constant blood calcium concentration of about 10 mg/100 mL.
Major functions of calcium inside the body include the formation and maintenance of bones and teeth, the physiology of muscle contraction, the cell membrane integrity, the activity of several enzymes that have specific requirement for it, the coagulation of blood, and the regulation of acid-base balance.
Calcium acetate is a chemical compound which is calcium salt of acetic acid.
Calcium acetate has the formula Ca(C2H3O2)2.
Calcium acetate's standard name is calcium acetate, while calcium ethanoate is the systematic name.
An older name is acetate of lime.
The anhydrous form is very hygroscopic; therefore the monohydrate (Ca(CH3COO)2H2O) is the common form.
The Calcium acetate of acetic acid.
Calcium acetate is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces.
Calcium Acetate belongs to the group of calcium salts, widely used as phosphorus binders in patients with chronic renal failure.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
The anhydrous form is very hygroscopic; therefore the monohydrate (Ca(CH3COO)2·H2O) is the common form.
Calcium acetate, with the CAS number 62-54-4, is a chemical compound composed of calcium and acetic acid.
Calcium acetate appears as a white, odorless powder or crystalline solid and is highly soluble in water, making it useful in various applications.
Calcium acetate is often utilized in the food industry as a food preservative and flavoring agent, as well as in the pharmaceutical sector for its role in calcium supplementation.
Calcium acetate serves as a buffering agent in biochemical applications and is also employed in wastewater treatment processes to precipitate heavy metals.
Calcium acetate's chemical formula is C4H6CaO4, indicating that it contains two acetate ions for each calcium ion.
In terms of safety, calcium acetate is generally recognized as safe when used appropriately, but Calcium acetate should be handled with care to avoid ingestion in large quantities or exposure to dust.
Overall, calcium acetate is a versatile compound with significant industrial and health-related applications.
Calcium acetate Chemical Properties
Melting point: 160°C (dec.)
density: 1,5 g/cm3
refractive index: 1.5500
FEMA: 2228 | CALCIUM ACETATE
Fp: 160°C
storage temp.: Hygroscopic, Room Temperature, under inert atmosphere
solubility: H2O: 1 M at 20 °C, clear, colorless
form: Powder
color: white
Specific Gravity: 1.50
PH: 8(1 mM solution);8.43(10 mM solution);8.77(100 mM solution);9.13(1000 mM solution)
Odor: mild acetic
Odor Type: acetic
Water Solubility: soluble
Decomposition: 160 ºC
Stability: Stable. Non-flammable. Incompatible with strong oxidizing agents.
Major Application: pharmaceutical (small molecule)
Cosmetics Ingredients Functions VISCOSITY CONTROLLING
FRAGRANCE
Cosmetic Ingredient Review (CIR): Calcium acetate (62-54-4)
InChI: 1S/2C2H4O2.Ca/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
InChIKey: VSGNNIFQASZAOI-UHFFFAOYSA-L
LogP: -0.29
CAS DataBase Reference: 62-54-4(CAS DataBase Reference)
EPA Substance Registry System: Calcium acetate (62-54-4)
Calcium acetate occurs as a white or almost white, odorless or almost odorless, hygroscopic powder.
Uses
Calcium acetate is used as a food additive and a mordant to fix dyes in the textile industry.
Calcium acetate is used as an alkali (base) in the manufacture of soaps, to improve some lubricants, and as an antimold to preserve baked goods for a longer shelf life.
Calcium Acetate is the calcium salt of acetic acid which functions as a sequestrant and mold control agent.
Calcium acetate contains approximately 25% calcium. it is a white odorless powder which is readily soluble in water with a solubility of approximately 37 g in 100 g water at 0°c.
Calcium acetate's solubility decreases with increasing temperature, with a sol- ubility of approximately 29 g in 100 g of water at 100°c.
Calcium acetate is the salt of acetic acid which is used as a preservative and sequestrant.
Calcium Acetate is a salt of acetic acid (A167640), a common chemical reagent used in a multitude of organic reactions.
Calcium acetate is the primary constituent of vinegar, contributing to its distinct taste and odor.
Calcium acetate is used in the synthesis of dye-sensitized solar cells.
In kidney disease, blood levels of phosphate may rise (called hyperphosphatemia) leading to bone problems.
Calcium acetate binds phosphate in the diet to lower blood phosphate levels.
Calcium acetate is used as a food additive, as a stabilizer, buffer and sequestrant, mainly in candy products under the number E263.
Tofu is traditionally obtained by coagulating soy milk with calcium sulfate.
Calcium acetate has been found to be a better alternative; being soluble, it requires less skill and a smaller amount.
Because Calcium acetate is inexpensive, calcium acetate was once a common starting material for the synthesis of acetone before the development of the cumene process:
Ca(CH3COO)2 → CaCO3(s) + (CH3)2CO
A saturated solution of calcium acetate in alcohol forms a semisolid, flammable gel that is much like "canned heat" products such as Sterno.
Chemistry teachers often prepare "California Snowballs", a mixture of calcium acetate solution and ethanol.
The resulting gel is whitish in color, resembling a snowball and can be lit on fire; it will burn for around 20 minutes.
Pharmaceutical Applications
Calcium acetate is used as a preservative in oral and topical formulations.
Therapeutically, parenteral calcium acetate acts as a source of calcium ions for hypocalcemia or electrolyte balance.
Oral calcium acetate is used as a complexing agent for hyperphosphatemia in dialysis patients.
Calcium acetate is also used in the food industry as a stabilizer, buffer and sequestrant.
Production method
Calcium acetate is obtained by the reaction between calcium carbonate and acetic acid.
Preparation method of anhydrous calcium acetate: the refined powder of calcium carbonate is added to the water, stirred into a suspension; added separately of a small amount of glacial acetic acid.
After completion of the reaction, the filtrate was concentrated in a water bath and a white solid, anhydrous calcium acetate, was precipitated from the viscous filtrate.
Calcium acetate is obtained by the neutralization between coke acid (wood acetic acid) and calcium hydroxide, followed by the evaporation of the filtrate and recrystallization.
Calcium acetate is obtained by the reaction between the reaction between acetic acid and calcium hydroxide or calcium carbonate.
Filter, concentrate and cool to obtain the dihydrate (colorless crystal), heated to 84 °C in a water salt (colorless crystal), heated to 100 °C to obtain the anhydrous salt.
Shellfish can be taken as raw materials, washed, crushed and dried for 1 h, subjecting to barbecue for 2 hour at 900~l000 ℃, then being added water to make a 1.3~1.5mol/L lime milk.
And then neutralized with acetic acid to clarify, filter with the filtrate concentrated, and finally dried at 120~140 °C to get the final product with a yield of 91.28%.
To a 20% acetic acid solution, add calcium carbonate powder to until there is no longer any CO2 gas escaping, then add a small amount of calcium carbonate, heated 80 ° C for reaction of 2-3h.
The filtrate was heated and concentrated with water bath while adding a small amount of 80% acetic acid at the same time to precipitate the calcium acetate monohydrate (what precipitated after the cooling of the solution is dihydrate), and finally dried at 60~70 ℃to derive the products.
Production Methods
Calcium acetate can be prepared by soaking calcium carbonate (found in eggshells, or in common carbonate rocks such as lime stone or marble) in vinegar:
CaCO3 + 2CH3COOH → Ca(CH3COO)2 + H2O + CO2
Since both reagents would have been available pre-historically, the chemical would have been observable as crystals then.
