CYCLOHEXANONE

Cyclohexanone is a colorless to pale yellow liquid organic compound with a distinct, acetone-like odor, widely used as a solvent and chemical intermediate in industrial applications.
Cyclohexanone can also be used as a solvent in a variety of products, including paints, lacquers, and resins. 
Cyclohexanone has not been found to occur in natural processes.

CAS Number: 108-94-1
Molecular Formula: C6H10O
Molecular Weight: 98.14
EINECS Number: 203-631-1

Synonyms: CYCLOHEXANONE, 108-94-1, Ketohexamethylene, Pimelic ketone, Sextone, Nadone, Anone, Anon, Cyclohexanon, Hexanon, Hytrol O, ketocyclohexane, oxocyclohexane, Pimelin ketone, Cicloesanone, Cykloheksanon, Hytrolo, Cyclic ketone, NCI-C55005, Cyclohexanon [Dutch], RCRA waste number U057, Caswell No. 270, Cicloesanone [Italian], Cykloheksanon [Polish], NSC 5711, CCRIS 5897, UNII-5QOR3YM052, MFCD00001625, HSDB 186, EINECS 203-631-1, UN1915, EPA Pesticide Chemical Code 025902, 5QOR3YM052, DTXSID6020359, CHEBI:17854, AI3-00041, NSC-5711, CYCLOHEXANONE [MI], CYCLOHEXANONE [FHFI], CYCLOHEXANONE [HSDB], CYCLOHEXANONE [IARC], CHEMBL18850, DTXCID00359, EC 203-631-1, UN 1915, CYCLOHEXANON (DUTCH), CYCLOHEXANONE (IARC), CYH, CICLOESANONE (ITALIAN), CYKLOHEKSANON (POLISH), CAS-108-94-1, RCRA waste no. U057, cylcohexanone, cylohexanone, cyclo-hexanone, 2-cyclohexanone, 4-cyclohexanone, Cyclohexanone,(S), Cyclohexanon(dutch), Caswell no 270, Cyclohexanone ACS grade, BDBM6, Cyclohexanone, 99.8%, WLN: L6VTJ, bmse000405, CYCLOHEXANONE [INCI], Cyclohexanone (ACGIH:OSHA), MLS002152896, BIDD:ER0292, Cyclohexanone, LR, >=99%, Cyclohexanone, p.a., 99.0%, Cyclohexanone, AR, >=99.5%, NSC5711, Cyclohexanone, analytical standard, HMS3039C04, Tox21_202121, Tox21_302750, s6236, STL183287, AKOS000119815, DB02060, FC02353, Cyclohexanone, ACS reagent, >=99.0%, Cyclohexanone, ReagentPlus(R), 99.8%, NCGC00091786-01, NCGC00091786-02, NCGC00256489-01, NCGC00259670-01, 9075-99-4, SMR001224507, Anoncaswellno270, Cicloesanone, Cykloheksanon, Cyclohexanone Manufacturer, CYCLOHEXANONE, REAGENT (ACS)CYCLOHEXANONE, REAGENT (ACS)CYCLOHEXANONE, REAGENT (ACS), AKOS BBS-00004296, PIMELIC KETONE

Cyclohexanone is a colorless, clear liquid with soil smell,  its impure product appears as light yellow color. 
Cyclohexanone is miscible with several other solvents. easily soluble in ethanol and ether. 
The lower exposure limit is 1.1% and the upper exposure limit is 9.4%. 

Cyclohexanone may be incompatible with oxidizers and nitric acid.
Cyclohexanone is a primarily used in industry, up to 96%, as a chemical intermediate in the production of nylons 6 and 66.
Oxidation or conversion of cyclohexanone yields adipic acid and caprolactam, two of the immediate precursors to the respective nylons.  

Cyclohexanone has the molecular formula C₆H₁₀O and belongs to the class of cyclic ketones, meaning it contains a six-membered carbon ring with a single ketone functional group.
Cyclohexanone is naturally flammable and volatile, requiring careful handling due to its potential health and environmental hazards.
Cyclohexanone is commonly produced by the oxidation of cyclohexane or the hydrogenation of phenol, both of which are large-scale industrial processes. 

One of its most important uses is as a precursor in the production of nylon, specifically in the synthesis of adipic acid and caprolactam, which are key building blocks of nylon-6 and nylon-6,6 polymers. 
Due to its solvent properties, cyclohexanone is also used in the formulation of paints, coatings, adhesives, and inks, as well as in the extraction of essential oils and pharmaceuticals.
Cyclohexanone is the organic compound with the formula (CH2)5CO. 

The molecule consists of six-carbon cyclic molecule with a ketone functional group. 
This colorless oily liquid has a sweet odor reminiscent of benzaldehyde. 
Over time, samples of cyclohexanone assume a pale yellow color.

Cyclohexanone is slightly soluble in water and miscible with common organic solvents. 
Millions of tonnes are produced annually, mainly as a precursor to nylon.
Cyclohexanone derived resin used in paints and varnishes caused contact dermatitis in painters.

A colorless liquid alkane that is commonly used as a solvent and in the production of hexanedioic acid (adipic acid) for the manufacture of nylon.
Cyclohexanone, itself, is manufactured by the reformation of longer chain hydrocarbons present in crude-oil fractions.
Cyclohexanone is also interesting from a structural point of view, existing as a ‘puckered’ six-membered ring, having all bonds between carbon atoms at 109.9° (the tetrahedral angle).

The molecule undergoes rapid interconversion between two ‘chair-like’ conformation, which are energetically equivalent, passing through a ‘boat-like’ structure of higher energy. 
Cyclohexanone is commonly represented by a hexagon.
Cyclohexanone is fractionated from crude oil and may be released wherever petroleum products are rened, stored, and used.

Cyclohexanone is prepared synthetically from benzene, by hydrocracking of cyclopentane, or from toluene by simultaneous dealkylation and double bond hydrogenation.
The compound was discovered by Edmund Drechsel [de] in 1888 among the products of AC electrolysis of slightly acidified water solutions of phenol. 
He named it hydrophenoketone and correctly suggested that phenol was first hydrogenated by electrolytic hydrogen to cyclohexanol, which he wasn't able to isolate, and then oxidized by electrolytic oxygen.

Cyclohexanone can be prepared from cyclohexanol by oxidation with chromium trioxide (Jones oxidation). 
An alternative method utilizes the safer and more readily available oxidant sodium hypochlorite.
Cyclohexanone is a primary aliphatic amine consisting of Cyclohexanone carrying an amino substituent.

Cyclohexanone has a role as a human xenobiotic metabolite and a mouse metabolite.
Cyclohexanone is a conjugate base of a cyclohexylammonium.
On distillation with water, Cyclohexanone forms azeotropic mixt, boiling @ 96.4 °C @ 760 mm Hg,  reacts with excess ammonia and zinc chloride @ 350 °C to produce alpha-picoline

Cyclohexanone is produced by the oxidation of cyclohexane in air, typically using cobalt catalysts: C6H12 + O2 → (CH2)5CO + H2O
This process forms cyclohexanol as a by-product, and this mixture, called "KA Oil" for ketone-alcohol oil, is the main feedstock for the production of adipic acid. 
The oxidation involves radicals and the hydroperoxide C6H11O2H as an intermediate. 

In some cases, purified cyclohexanol, obtained by hydration of cyclohexene, is the precursor. 
Alternatively, cyclohexanone can be produced by the partial hydrogenation of phenol: C6H5OH + 2 H2 → (CH2)5CO
This process can also be adjusted to favor the formation of cyclohexanol.

ExxonMobil developed a process in which benzene is hydroalkylated to cyclohexylbenzene. 
This latter product is oxidized to a hydroperoxide and then cleaved into phenol and cyclohexanone.
Therefore, this newer process without producing the acetone by-product appears attractive and is similar to the cumene process as a hydroperoxide is formed and then decomposed to yield two key products.

Cyclohexanone appears as a clear colorless liquid with a petroleum-like odor.
Cyclohexanone is used in making nylon, as a solvent, as a paint remover and in making other chemicals.
Flash point -4°F. Density 6.5 lb/gal (less than water) and insoluble in water.

Vapors heavier than air.
Cyclohexanone is a cycloalkane with the molecular formula C6H12. Cyclohexanone is non-polar.
Cyclohexanone is a colorless, ammable liquid with a distinctive detergent-like odor reminiscent of (sometimes used in) cleaning products.

Cyclohexanone is mainly used for the industrial production of adipic acid and caprolactam, the precursors of nylon.
Cyclohexanone (also known as CYX, hexamethylene, hexahydrobenzene, hexanaphthene, and benzenehexahydride) is a colorless, volatile and ammable liquid with the formula C6H12.
Cyclohexanone has a slight odor and is insoluble in water, but soluble in alcohol, ether, acetone, benzene, and ligroin.

Cyclohexanone occurs naturally in crude oil, volcanic gases, and cigarette smoke.
Cyclohexanone is an organic compound, belonging to the aliphatic amine class.
Cyclohexanone is a colorless liquid, although, like many amines, samples are often colored due to contaminants.

Cyclohexanone has a shy odor and is miscible with water.
Like other amines, Cyclohexanone is a weak base, compared to strong bases such as NaOH, but it is a stronger base than its aromatic analog, aniline.
Cyclohexanone is a useful intermediate in the production of many other organic compounds.

Cyclohexanone is used as an intermediate in synthesis of other organic compounds.
Cyclohexanone is the precursor to sulfenamide-based reagents used as accelerators for vulcanization.
Cyclohexanone is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators).

The amine itself is an eective corrosion inhibitor. Some sweeteners are derived from this amine, notably cyclamate.
The herbicide hexazinone and the anesthetic hexylcaine are derived from Cyclohexanone.
Cyclohexanone is corrosive.

Melting point: -47 °C (lit.)
Boiling point: 155 °C (lit.)
Density: 0.947 g/mL at 25 °C (lit.)
Vapor density: 3.4 (vs air)
Vapor pressure: 3.4 mm Hg (20 °C)
Refractive index: n20/D 1.450 (lit.)
FEMA: 3909 | CYCLOHEXANONE
Flash point: 116 °F
Storage temp.: Store at +5°C to +30°C.
Solubility: 90 g/L
pKa: 17 (at 25℃)
Form: Liquid
Color: APHA: ≤10
Relative polarity: 0.281
pH: 7 (70 g/L, H₂O, 20℃)
Odor: Like peppermint and acetone.
Odor Type: Minty
Biological source: Synthetic
Explosive limit: 1.1%, 100°F
Water Solubility: 150 g/L (10 ºC)
Merck: 14,2726
JECFA Number: 1100
BRN: 385735
Henry's Law Constant: 1.2 x 10⁻⁵ atm·m³/mol at 25 °C (Hawthorne et al., 1985), 6.92 x 10⁻⁵ atm·m³/mol at 60.00 °C, 10.7 at 70.00 °C, 16.4 at 80.00 °C (headspace-GC, Hovorka et al., 2002)
Exposure limits: TLV-TWA 100 mg/m³ (25 ppm) (ACGIH), IDLH 5000 ppm (NIOSH).
Dielectric constant: 18.2 (20℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 0.86 at 25℃
Surface tension: 33.74 mN/m at 298.15K

Cyclohexanone, a colorless liquid is a cyclic ketone. 
Cyclohexanone is an important building block for the synthesis of a variety of organic compounds. 
Majority of the cyclohexanone synthesized is utilized as an intermediate in the synthesis of nylon.

Used as a polyvinyl chloride (PVC) solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. 
Cyclohexanone probably does not cross react with cyclohexanone resin. 
Cyclohexanone is a water-white to slightly yellow liquid with a peppermint-like or acetone-like odor.

Clear, colorless to pale yellow, oily liquid with a peppermint-like odor.
Cyclohexanone also known as OxoCyclohexanone, pimelic ketone, cyclohexyl ketone, and CYC is a clear oily liquid that has a colourless to light yellow tinge, a pungent odour and has the molecular formula C6H10O, CAS:108-94-1.
Cyclohexanone has a specic gravity of 0.945 and a ash point of 46 °C.

Cyclohexanone is slightly soluble in water and is completely miscible with common solvents.
Cyclohexanone occurs naturally in crude oils and is also produced synthetically, in large quantities, as it is a key intermediate in the production of nylon.
Cyclohexanone is mostly captively consumed, either isolated or as a mixture, in the production of nylon intermediates (adipic acid and Caprolactam).

Around 4% is consumed in markets other than nylon, such as solvents for paints, dyes and pesticides.
Cyclohexanone is also used in the manufacture of pharmaceuticals, lms, soaps and coatings.
Cyclohexanone is produced from either phenol or Cyclohexanone.

Fibrant masters technologies that use any of these feedstocks
Cyclohexanone has developed a unique technology portfolio to secure a reliable and high quality raw material supply to its Caprolactam units.
Cyclohexanone (also known as oxoCyclohexanone, pimelic ketone, cyclohexyl ketone, and CYC) is a clear oily liquid that has a colourless to light yellow tinge and a pungent odour.

Cyclohexanone is a sixcarbon cyclic molecule belonging to the class of cyclic ketones (organic compounds) with the formula C6H10O.
Cyclohexanone is slightly soluble in water, completely miscible with common solvents and reacts with oxidants such as nitric acid.
Cyclohexanone occurs naturally in crude oils and is also produced synthetically, in large quantities, as it is a key intermediate in the production of nylon.

Cyclohexanone is an alicyclic hydrocarbon containing a ring of six carbon atoms,  The cyclic form of hexane, used as a raw material in the production of nylon.
Cyclohexanone has a role as a non-polar solvent.
Cyclohexanone is a cycloalkane and a volatile organic compound

A cyclic ketone that consists of cyclohexane bearing a single oxo substituent.
A colorless to pale yellow liquid with a pleasant odor. Less dense than water. 
Cyclohexanone is used to make nylon, as a chemical reaction medium, and as a solvent.

Cyclohexanone forms an explosive peroxide with H2O2, and reacts vigorously with oxidizing materials (nitric acid).
If Cyclohexanone gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least 15 min, occasionally lifting upper and lower lids.
If Cyclohexanone contacts theskin, remove contaminated clothing and wash immediately with soap and water. 

If Cyclohexanone has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. 
Transfer promptly to a medical facility. 

When this chemical has been swallowed, get medical attention. 
Give large quantities of water and inducevomiting. 
Cyclohexanone has a role as a human xenobiotic metabolite.

Cyclohexanone (also known as oxoCyclohexanone, pimelic ketone, ketohexamethylene, cyclohexyl ketone or ketoCyclohexanone) is a six-carbon cyclic molecule with a ketone functional group.
Cyclohexanone is a colorless, oily liquid with an acetone-like smell.
Cyclohexanone is the organic compound with the formula (CH2)5CO.

The molecule consists of six-carbon cyclic molecule with a ketone functional group.
This colorless oil has an odor reminiscent of that of acetone. Over time, samples of cyclohexanone assume a yellow color.
Cyclohexanone is slightly soluble in water and miscible with common organic solvents.

Billions of kilograms are produced annually, mainly as a precursor to nylon.
Cyclohexanone, a colorless liquid is a cyclic ketone.
In laboratory and industrial settings, cyclohexanone is recognized as a moderately hazardous chemical, capable of causing irritation to the skin, eyes, and respiratory system if inhaled or exposed in significant quantities. 

Its vapors can form explosive mixtures with air, making it crucial to store and handle it in well-ventilated areas with proper safety precautions.
Beyond its industrial applications, cyclohexanone can also be found in trace amounts in certain natural substances, though its primary significance remains in synthetic chemistry and manufacturing. 
Its unique combination of reactivity and solvency makes it an essential component in various chemical processes across multiple industries.

Production method Of Cyclohexanone:
In the 1940s, the industrial production of cyclohexanone mainly applied hydrogenation of phenol to generate cyclohexanol, followed by dehydrogenation to give cyclohexanone. 
In the 1960s, with the development of petrochemical industry, the cyclohexane oxidation production method gradually dominated. 
In 1967, the one step method of phenol hydrogenation, developed by the Netherlands National Mining Company (DSM) was industrialized. 

This method has short production process, good product quality and high yield, but the raw materials of phenol and catalyst are expensive, so the majority of the industry still adopts the cyclohexane oxidation method.
Phenol method takes nickel as a catalyst, first apply hydrogenation of phenol to give cyclohexanol, followed by dehydrogenation to give cyclohexanone using zinc as the catalyst for zinc.
Cyclohexane oxidation method uses cyclohexane as the raw material, first apply non-catalyst condition, use oxygen-rich air for oxidation to give cyclohexyl hydroperoxide, followed by decomposition into the mixture of cyclohexanol, cyclohexanone, alcohol and ketone in the presence of tert-butyl chromate catalyst, further apply a series of distillation refinement to get qualified products. 

Benzene hydrogenation oxidation method,  benzene subjects to hydrogenation (with hydrogen) at 120-180 ℃ in the presence of nickel catalyst to generate cyclohexane,  cyclohexane has oxidation reaction with air at 150-160 ℃, 0.908MPa to obtain the mixture of cyclohexanol and cyclohexanone, separate them to obtain the cyclohexanone product.
Cyclohexanol is dehydrogenated at 350-400 ° C in the presence of a zinc-calcium catalyst to produce cyclohexanone.

Uses Of Cyclohexanone:
Cyclohexanone is an important chemical raw material, being the major intermediates of making nylon, caprolactam and adipic acid. 
Cyclohexanone is also an important industrial solvent, for example, for paints, especially for those containing nitrocellulose, vinyl chloride polymers and their copolymers or methacrylate polymer paints. 
Used as an excellent solvent for pesticides such as organophosphate insecticide. 

Cyclohexanone is used as a solvent for dyes, viscous solvents for piston aviation lubricants, solvents for greases, waxes and rubbers. 
Also used as leveling agent for dyeing and fading silk,  degreasing agents for polishing metal,  wood coloring paint,  also used for cyclohexanone stripping, decontamination and spot removal. 
Cyclohexanone and cyanoacetic acid can have condensation reaction to generate cyclohexylidene acetic acid, and then followed by elimination and decarboxylation to get cyclohexene acetonitrile, and finally giving cyclohexene ethylamine by hydrogenation. 

Cyclohexene ethylamine is a intermediate for some drugs.
Industrial solvent for cellulose acetate resins, vinyl resins, rubber, and waxes, solventsealer for polyvinyl chloride, in printing industry,  coating solvent in audio and videotape production
Cyclohexanone is registered under the REACH Regulation and is manufactured in and/or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

Cyclohexanone is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Cyclohexanone is used in the following products: coating products, inks and toners, adhesives and sealants, biocides (e.g. disinfectants, pest control products), plant protection products and polymers.
Other release to the environment of Cyclohexanone is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Release to the environment of Cyclohexanone can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Other release to the environment of Cyclohexanone is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

Cyclohexanone can be found in complex articles, with no release intended: vehicles.
Cyclohexanone can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), wood (e.g. floors, furniture, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Cyclohexanone is used in the following products: coating products, adhesives and sealants, laboratory chemicals, inks and toners, plant protection products, biocides (e.g. disinfectants, pest control products) and fillers, putties, plasters, modelling clay.

Cyclohexanone is used in the following areas: building & construction work, printing and recorded media reproduction and agriculture, forestry and fishing.
Cyclohexanone is used for the manufacture of: machinery and vehicles and furniture.
Other release to the environment of Cyclohexanone is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Cyclohexanone is used in the following products: coating products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), plant protection products, inks and toners and fillers, putties, plasters, modelling clay.
Release to the environment of Cyclohexanone can occur from industrial use: formulation of mixtures and formulation in materials.
Cyclohexanone is used in the following products: coating products, adhesives and sealants, inks and toners, laboratory chemicals, fillers, putties, plasters, modelling clay, plant protection products and biocides (e.g. disinfectants, pest control products).

Cyclohexanone has an industrial use resulting in manufacture of another substance (use of intermediates).
Cyclohexanone is used in the following areas: printing and recorded media reproduction, building & construction work and agriculture, forestry and fishing.
Cyclohexanone is used for the manufacture of: chemicals, machinery and vehicles and furniture.

Release to the environment of Cyclohexanone can occur from industrial use: in processing aids at industrial sites, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).
Other release to the environment of Cyclohexanone is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Cyclohexanone is used as an industrial solvent and paint remover. 
It acts as a precursor to nylon 6,6 and nylon 6 and cyclohexanone oxime, which gives caprolactam on rearrangement. 
Further, Cyclohexanone is used as a chemical reaction medium, adhesives, sealants and agricultural products.

Cyclohexanone is used in the productionof adipic acid for making nylon, in thepreparation of cyclohexanone resins, and asa solvent for nitrocellulose, cellulose acetate,resins, fats, waxes, shellac, rubber, and DDT.
Used as a polyvinyl chloride solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. 
Cyclohexanone probably does not cross-react with cyclohexanone resin. 

A cyclohexanone-derived resin used in paints and varnishes caused contact dermatitis in painters
The great majority of cyclohexanone is consumed in the production of precursors to Nylon 6,6 and Nylon 6. 
About half of the world's supply is converted to adipic acid, one of two precursors for nylon 6,6. 

For this application, the KA oil (see above) is oxidized with nitric acid. 
The other half of the cyclohexanone supply is converted to cyclohexanone oxime. 
In the presence of sulfuric acid catalyst, the oxime rearranges to caprolactam, a precursor to nylon 6.

Cyclohexanone has been used in the illicit production of phencyclidine and its analogs and is often subject to purchase restrictions, such as being listed on the Special Surveillance List in the US.
Cyclohexanone is also an important industrial solvent, for example, for paints, especially for those containing nitrocellulose, vinyl chloride polymers and their copolymers or methacrylate polymer paints. Used as an excellent solvent for pesticides such as organophosphate insecticide.
Cyclohexanone is used as a solvent for dyes, viscous solvents for piston aviation lubricants, solvents for greases, waxes and rubbers.

Also used as leveling agent for dyeing and fading silk,  degreasing agents for polishing metal,  wood coloring paint,  also used for cyclohexanone stripping, decontamination and spot removal.
Cyclohexanone and cyanoacetic acid can have condensation reaction to generate cyclohexylidene acetic acid, and then followed by elimination and decarboxylation to get cyclohexene acetonitrile, and nally giving cyclohexene ethylamine by hydrogenation.
Cyclohexene ethylamine is a intermediate for some drugs.

The solvents for bers, resins, rubbers, parans, shellac and DDT,  for organic synthesis,  it can dissolve many of the complexes formed by the elements and organic reagents,  bismuth determination,  extract rare metal such as uranium, thorium, cobalt and titanium.
Cyclohexanone is used as an additive in agricultural pesticides.
Cyclohexanone is used in the plastic industry.

Cyclohexanone is used in the adhesive industry.
Cyclohexanone is used in the paint and varnish industry.
Cyclohexanone is mostly captively consumed, either isolated or as a mixture, in the production of nylon intermediates (adipic acid and Caprolactam). 

Around 4% is consumed in markets other than nylon, such as solvents for paints, dyes and pesticides. 
Cyclohexanone is also used in the manufacture of pharmaceuticals, films, soaps and coatings.
Fibrant is one of the largest producers of Cyclohexanone, a raw material used in the production of Caprolactam.

In addition to the large scale reactions conducted in service of the polymer industry, many reactions have been developed for cyclohexanone.
In the presence of light, it undergoes alpha-chlorination to give 2-chlorocyclohexanone.
Cyclohexanone forms a trimethylsilylenol ether upon treatment with trimethylsilylchloride in the presence of base.

It forms an enamine with pyrrolidine.
Treatment with nitrosyl chloride and ethanol in sulfur dioxide gives the oximinecarboxylic ester.
Cyclohexanone is used as a solvent for lacquers, paints, resins, degreasers, spot removers, polymers, copolymers, waxes, crude rubber, cellulose acetate, the manufacturing of herbicides and anihistamines.

Cyclohexanone is used predominantly in the nylon industry, where about 90% is consumed in the industrial production of adipic acid and caprolactam, which are themselves used to produce nylon6 and nylon.
The remaining 10% is used both as a solvent and plasticizer for paints, resins, varnish and oil.
Cyclohexanone is also used as an intermediate in the manufacture of other industrial chemicals such as Cyclohexanone, cyclohexanone, and nitrocyclohexanone.

Cyclohexanone is a water-white to slightly yellow liquid with a peppermint-like or acetone-like odor.
Industrial solvent for cellulose acetate resins, vinyl resins, rubber, and waxes,  solventsealer for polyvinyl chloride,  in printing industry,  coating solvent in audio and videotape production Cyclohexanone is a petroleum product obtainedby distilling C4- 400°F boiling rangenaphthas, followed by fractionation andsuperfractionation,  also formed by catalytichydrogenation of benzene.
Cyclohexanone is usedextensively as a solvent for lacquers andresins, as a paint and varnish remover, andin the manufacture of adipic acid, benzene,cyclohexanol, and cyclohexanone.

Storage Of Cyclohexanone:
Color Code—Red: Flammability Hazard: Store ina flammable liquid storage area or approved cabinet awayfrom ignition sources and corrosive and reactive materials.
Prior to working with Cyclohexanone you should be trainedon its proper handling and storage. 
Before entering confinedspace where this chemical may be present, check to make sure that an explosive concentration does not exist.

Cyclohexanone must be stored to avoid contact with oxidizers (such as perchlorates, peroxides, chlorates, nitrates, andpermanganates), since violent reactions occur. 
Store intightly closed containers in a cool well-ventilated area awayfrom heat, sparks, and flames. Metal containers involvingthe transfer of this chemical should be grounded andbonded. 
Where possible, automatically pump liquid fromdrums or other storage containers to process containers.

Drums must be equipped with self-closing valves, pressurevacuum bungs, and flame arresters. 
Use only nonsparkingtools and equipment, especially when opening and closingcontainers of this chemical. 
Sources of ignition, such assmoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could createa potential fire or explosion hazard. 

Wherever this chemicalis used, handled, manufactured, or stored, use explosionproof electrical equipment and fittings.
Cyclohexanone requires a “FLAMMABLELIQUID” label. 
Cyclohexanone falls in Hazard Class 3 and PackingGroup II.

Health Hazard Of Cyclohexanone:
The toxicity of cyclohexanone in test specieswas found to be low to moderate. 
Exposureto its vapors can produce irritation in the eyesand throat. 
Splashing into the eyes can damagethe cornea. 

Throat irritation in humansmay occur from 3–5 minute exposure to a50-ppm concentration in air. 
The symptomsof chronic toxicity in animals from its inhalationwere liver and kidney damage, as wellas weight loss. 

However, its acute toxicitywas low below 3000 ppm. 
The symptomsin guinea pigs were lacrimation, salivation,lowering of heart rate, and narcosis. 
Exposureto 4000 ppm for 4–6 hours was lethalto rats and guinea pigs.

Fire Hazard Of Cyclohexanone:
Will be easily ignited by heat, sparks or flames. 
Vapors may form explosive mixtures with air vapors may travel to source of ignition and flash back. 
Most vapors are heavier than air. 

They will spread along ground and collect in low or confined areas (sewers, basements, tanks). 
Vapor explosion hazard indoors, outdoors or in sewers. 

Runoff to sewer may create fire or explosion hazard. 
Containers may explode when heated. 
Many liquids are lighter than water.

Safety Profile Of Cyclohexanone:
Suspected carcinogen moderately toxic by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. 
A skin and severe eye irritant. 
Human systemic effects by inhalation: changes in the sense of smell, conjunctiva irritation, and unspecified respiratory system changes. 

Human irritant by inhalation mdd narcotic properties have also been ascribed to it. 
Human mutation data reported experimental reproductive effects. 

Flammable liquid when exposed to heat or flame,  can react vigorously with oxidizing materials. 
Slight explosion hazard in its vapor form, when exposed to flame reaction with hydrogen peroxide + nitric acid forms an explosive peroxide. 
To fight fire, use alcohol foam, dry chemical, or COa when heated to decomposition it emits acrid smoke and irritating fumes.