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Delta-Gluconolactone is a water-soluble cyclic ester of D-gluconic acid that gradually hydrolyzes in aqueous systems to produce gluconic acid.
Delta-Gluconolactone functions as a slow-release acidifier, acidity regulator, raising agent, sequestrant, curing aid, pickling agent, coagulant, pH-control agent, and formulation aid.
Delta-Gluconolactone is widely used in bakery products, dairy foods, tofu, processed meats, seafood, beverages, fruit and vegetable processing, pharmaceuticals, cosmetics, detergents, and specialty chemical formulations.
CAS Number: 90-80-2
EC Number: 202-016-5
Molecular Formula: C6H10O6
Molecular Weight: 178.14 g/mol
Synonyms: Delta-Gluconolactone, δ-Gluconolactone, Glucono Delta-Lactone, Glucono-Delta-Lactone, Glucono-d-Lactone, GDL, D-Glucono-1,5-Lactone, D-Gluconic Acid Delta-Lactone, D-Gluconic Acid δ-Lactone, Gluconic Acid Lactone, Gluconolactone, D-Gluconolactone, D-(+)-Glucono-Delta-Lactone, D-(+)-Gluconic Acid δ-Lactone, D-Glucono-d-Lactone, D-Gluconic Acid 1,5-Lactone, Gluconic Acid 1,5-Lactone, Gluconic Delta-Lactone, 1,5-Gluconolactone, Glucono-1,5-Lactone, D-Gluconic Acid Cyclic Ester, Dextronic Acid Delta-Lactone, D-(+)-Dextronic Acid δ-Lactone, 1,2,3,4,5-Pentahydroxycaproic Acid δ-Lactone, E575, E 575, INS 575, Food-Grade Gluconolactone, Pharmaceutical-Grade Gluconolactone, Cosmetic-Grade Gluconolactone, Slow-Release Food Acidulant, Encapsulated-Effect Acidifier, Tofu Coagulant, Dairy Acidifier, Meat-Curing Acidifier, Bakery Leavening Acid, Food Sequestrant, Polyhydroxy Acid, PHA Gluconolactone, Gluconic Acid Precursor
APPLICATIONS
Delta-Gluconolactone is used as a slow-release acidifier in food-processing applications.
Delta-Gluconolactone is used to lower pH gradually after dissolution in water.
Delta-Gluconolactone is used where immediate addition of a strong food acid would cause localized over-acidification.
Delta-Gluconolactone is used to provide controlled and uniform acid development throughout a food product.
Delta-Gluconolactone is used as an acidity regulator.
Delta-Gluconolactone is used to establish the desired final pH in formulated foods.
Delta-Gluconolactone is used to stabilize acidity during processing and storage.
Delta-Gluconolactone is used to modify flavor, texture, preservation, and protein behavior through controlled acidification.
Delta-Gluconolactone is used as food additive E575.
Delta-Gluconolactone is used as food additive INS 575.
Delta-Gluconolactone is used in food products under applicable good-manufacturing-practice conditions.
Delta-Gluconolactone is used only in grades meeting relevant food-purity and regulatory specifications.
Delta-Gluconolactone is used as a raising agent in bakery formulations.
Delta-Gluconolactone is used as a leavening acid with sodium bicarbonate.
Delta-Gluconolactone is used to release carbon dioxide gradually during dough or batter processing.
Delta-Gluconolactone is used to provide controlled leavening in products requiring delayed gas generation.
Delta-Gluconolactone is used in chemically leavened bread products.
Delta-Gluconolactone is used in cakes requiring uniform internal structure.
Delta-Gluconolactone is used in muffins and quick breads.
Delta-Gluconolactone is used in bakery systems where controlled acid release improves process tolerance.
Delta-Gluconolactone is used in biscuits and cookies.
Delta-Gluconolactone is used in crackers and crisp baked products.
Delta-Gluconolactone is used in waffles and pancake mixes.
Delta-Gluconolactone is used in dry baking mixes containing alkaline leavening components.
Delta-Gluconolactone is used in refrigerated and frozen dough systems.
Delta-Gluconolactone is used where premature carbon-dioxide release must be minimized.
Delta-Gluconolactone is used to separate mixing activity from later leavening development.
Delta-Gluconolactone is used to improve consistency between preparation and baking.
Delta-Gluconolactone is used in doughnut and fried-batter formulations.
Delta-Gluconolactone is used in coated and battered foods.
Delta-Gluconolactone is used in tempura-style batter systems.
Delta-Gluconolactone is used to regulate gas formation and batter structure during heating.
Delta-Gluconolactone is used in tortilla and flatbread formulations.
Delta-Gluconolactone is used in bakery products requiring mild acidification.
Delta-Gluconolactone is used to modify dough pH without creating a sharply acidic taste.
Delta-Gluconolactone is used in combination with other leavening acids where a broader reaction profile is required.
Delta-Gluconolactone is used as a coagulant in tofu production.
Delta-Gluconolactone is used to coagulate soy proteins gradually and uniformly.
Delta-Gluconolactone is used in silken tofu formulations.
Delta-Gluconolactone is used to produce smooth, fine-textured soybean curd.
Delta-Gluconolactone is used in soft tofu.
Delta-Gluconolactone is used in packaged tofu coagulated within the final container.
Delta-Gluconolactone is used to reduce coarse curd formation during soy-protein coagulation.
Delta-Gluconolactone is used to produce consistent moisture retention in tofu products.
Delta-Gluconolactone is used in soy-based desserts.
Delta-Gluconolactone is used in soy-protein gels.
Delta-Gluconolactone is used in plant-based pudding and custard systems.
Delta-Gluconolactone is used to create controlled gelation in compatible plant-protein formulations.
Delta-Gluconolactone is used with calcium sulfate in blended tofu-coagulant systems.
Delta-Gluconolactone is used with magnesium salts when a modified curd structure is desired.
Delta-Gluconolactone is used to balance coagulation speed and gel firmness.
Delta-Gluconolactone is used after pilot testing establishes the appropriate coagulant combination.
Delta-Gluconolactone is used in dairy products as a gradual acidifying agent.
Delta-Gluconolactone is used to lower the pH of milk-protein systems.
Delta-Gluconolactone is used to promote controlled casein coagulation.
Delta-Gluconolactone is used to form smooth acid-set dairy gels.
Delta-Gluconolactone is used in fresh-cheese production.
Delta-Gluconolactone is used in soft-cheese formulations.
Delta-Gluconolactone is used in cream-cheese-type products.
Delta-Gluconolactone is used to control acidification without relying entirely on bacterial fermentation.
Delta-Gluconolactone is used in cottage-cheese and curd-type products.
Delta-Gluconolactone is used to support uniform milk-protein precipitation.
Delta-Gluconolactone is used to reduce localized protein damage during acid addition.
Delta-Gluconolactone is used to achieve controlled whey separation.
Delta-Gluconolactone is used in processed-cheese formulations where permitted.
Delta-Gluconolactone is used to regulate pH and protein interactions.
Delta-Gluconolactone is used to assist the development of desired melt and texture properties.
Delta-Gluconolactone is used in combination with emulsifying salts after formulation testing.
Delta-Gluconolactone is used in fermented-milk products.
Delta-Gluconolactone is used in heat-treated fermented-milk formulations where permitted.
Delta-Gluconolactone is used to supplement biological acid production.
Delta-Gluconolactone is used to standardize final acidity when fermentation variation must be controlled.
Delta-Gluconolactone is used in yogurt-style products.
Delta-Gluconolactone is used in dairy desserts requiring acid-set structure.
Delta-Gluconolactone is used in milk-based puddings and gels.
Delta-Gluconolactone is used to adjust acidity while maintaining a relatively mild flavor profile.
Delta-Gluconolactone is used in whey-protein cheese.
Delta-Gluconolactone is used to promote controlled precipitation of whey proteins.
Delta-Gluconolactone is used to adjust pH during thermal protein processing.
Delta-Gluconolactone is used in cheese systems according to applicable product standards.
Delta-Gluconolactone is used in imitation and plant-based cheese products.
Delta-Gluconolactone is used to acidify soy-, pea-, oat-, and nut-based protein systems.
Delta-Gluconolactone is used to promote gelation in selected dairy-alternative formulations.
Delta-Gluconolactone is used to adjust texture and flavor after protein-specific testing.
Delta-Gluconolactone is used in processed meat products.
Delta-Gluconolactone is used as a curing and acidification aid.
Delta-Gluconolactone is used to reduce pH gradually in comminuted meat formulations.
Delta-Gluconolactone is used to improve process consistency in fermented and cured meat systems.
Delta-Gluconolactone is used in dry and semidry sausages.
Delta-Gluconolactone is used in fermented sausage formulations.
Delta-Gluconolactone is used to supplement or partially replace microbial acid development.
Delta-Gluconolactone is used to accelerate attainment of the target product pH.
Delta-Gluconolactone is used in summer sausage.
Delta-Gluconolactone is used in salami-type products.
Delta-Gluconolactone is used in snack sticks and cured meat bars.
Delta-Gluconolactone is used to support predictable texture and tang development.
Delta-Gluconolactone is used in cooked sausage products.
Delta-Gluconolactone is used in emulsified meat systems.
Delta-Gluconolactone is used in meat loaves and formed products.
Delta-Gluconolactone is used to influence protein binding, moisture retention, and finished texture.
Delta-Gluconolactone is used in cured ham and pork products where permitted.
Delta-Gluconolactone is used to regulate brine or meat-system acidity.
Delta-Gluconolactone is used to support consistent curing reactions.
Delta-Gluconolactone is used only after evaluating color, flavor, yield, and microbial stability.
Delta-Gluconolactone is used in poultry products.
Delta-Gluconolactone is used in processed chicken and turkey formulations.
Delta-Gluconolactone is used to adjust the pH of marinades and injection solutions.
Delta-Gluconolactone is used after evaluating protein functionality and water-holding capacity.
Delta-Gluconolactone is used in seafood processing.
Delta-Gluconolactone is used in processed fish products.
Delta-Gluconolactone is used in surimi and formed seafood formulations.
Delta-Gluconolactone is used to regulate pH and gel formation in compatible fish-protein systems.
Delta-Gluconolactone is used in shrimp and shellfish processing where permitted.
Delta-Gluconolactone is used to regulate acidity in seafood preparations.
Delta-Gluconolactone is used to support preservation systems containing salt or other hurdles.
Delta-Gluconolactone is used after sensory and shelf-life testing.
Delta-Gluconolactone is used as a pickling agent.
Delta-Gluconolactone is used to produce gradual acidity in vegetable pickling solutions.
Delta-Gluconolactone is used to regulate the pH of brines.
Delta-Gluconolactone is used where a milder and more controlled acidification profile is desired.
Delta-Gluconolactone is used in pickled cucumbers.
Delta-Gluconolactone is used in pickled onions and mixed vegetables.
Delta-Gluconolactone is used in olives and vegetable antipasti.
Delta-Gluconolactone is used in combination with salt, vinegar, and other approved preservation components.
Delta-Gluconolactone is used in canned vegetables.
Delta-Gluconolactone is used to reduce product pH before or during thermal processing.
Delta-Gluconolactone is used to improve the uniformity of acidity within packed foods.
Delta-Gluconolactone is used only after validation of the complete thermal process.
Delta-Gluconolactone is used in canned tomatoes and tomato preparations.
Delta-Gluconolactone is used in sauces, purees, and vegetable concentrates.
Delta-Gluconolactone is used to adjust acidity while minimizing immediate flavor impact.
Delta-Gluconolactone is used to support preservation and texture-control systems.
Delta-Gluconolactone is used in fruit preparations.
Delta-Gluconolactone is used in jams, jellies, and fruit fillings.
Delta-Gluconolactone is used to adjust pH for pectin gelation.
Delta-Gluconolactone is used to provide gradual acid development during cooking or cooling.
Delta-Gluconolactone is used in fruit preserves.
Delta-Gluconolactone is used in bakery fruit fillings.
Delta-Gluconolactone is used in dessert toppings and fruit sauces.
Delta-Gluconolactone is used to balance sweetness and acidity in formulated products.
Delta-Gluconolactone is used in beverages as an acidity regulator.
Delta-Gluconolactone is used in flavored water and soft-drink formulations.
Delta-Gluconolactone is used in sports and electrolyte beverages where permitted.
Delta-Gluconolactone is used to provide a gradual and relatively mild acidic taste.
Delta-Gluconolactone is used in powdered beverage mixes.
Delta-Gluconolactone is used in instant drink powders.
Delta-Gluconolactone is used where acid development is desired only after water addition.
Delta-Gluconolactone is used with bicarbonates in effervescent beverage systems.
Delta-Gluconolactone is used in fruit beverages.
Delta-Gluconolactone is used in vegetable drinks.
Delta-Gluconolactone is used in dairy-based beverages after protein-stability evaluation.
Delta-Gluconolactone is used to regulate acidity without introducing the flavor profile of stronger organic acids.
Delta-Gluconolactone is used in beer and malt beverages where permitted.
Delta-Gluconolactone is used to adjust processing or finished-product acidity.
Delta-Gluconolactone is used in specialty fermented beverages.
Delta-Gluconolactone is used only after evaluating fermentation, flavor, and regulatory requirements.
Delta-Gluconolactone is used in cider, perry, and fruit-wine-type beverages where permitted.
Delta-Gluconolactone is used to standardize acidity.
Delta-Gluconolactone is used to improve flavor balance.
Delta-Gluconolactone is used after fermentation and storage-stability testing.
Delta-Gluconolactone is used in confectionery products.
Delta-Gluconolactone is used in hard and soft candy formulations.
Delta-Gluconolactone is used in chewing gum and compressed confectionery.
Delta-Gluconolactone is used to provide delayed tartness or gradual acid development.
Delta-Gluconolactone is used in fondants and icings.
Delta-Gluconolactone is used in cream and gel confectionery fillings.
Delta-Gluconolactone is used to regulate pH in sugar-based systems.
Delta-Gluconolactone is used to support flavor and texture development without abrupt acidification.
Delta-Gluconolactone is used in egg products.
Delta-Gluconolactone is used in dried and liquid egg formulations where permitted.
Delta-Gluconolactone is used to regulate acidity before further processing.
Delta-Gluconolactone is used after evaluating protein coagulation and sensory effects.
Delta-Gluconolactone is used in fresh pasta and noodle products where permitted.
Delta-Gluconolactone is used to regulate dough acidity.
Delta-Gluconolactone is used to influence texture and microbial stability.
Delta-Gluconolactone is used according to applicable food-category requirements.
Delta-Gluconolactone is used in ready-to-eat savory foods.
Delta-Gluconolactone is used in sauces, dressings, dips, and spreads.
Delta-Gluconolactone is used to regulate acidity and support preservation.
Delta-Gluconolactone is used after evaluating emulsion stability and flavor.
Delta-Gluconolactone is used in mayonnaise-type emulsions.
Delta-Gluconolactone is used in salad dressings.
Delta-Gluconolactone is used in vegetable and dairy-based dips.
Delta-Gluconolactone is used to provide controlled acidity during mixing and storage.
Delta-Gluconolactone is used in soups and bouillons.
Delta-Gluconolactone is used in dry seasoning preparations.
Delta-Gluconolactone is used in spice blends where permitted.
Delta-Gluconolactone is used to regulate acidity and improve ingredient stability.
Delta-Gluconolactone is used as a sequestrant.
Delta-Gluconolactone is used to generate gluconic acid capable of complexing selected metal ions.
Delta-Gluconolactone is used to reduce undesirable metal-catalyzed reactions.
Delta-Gluconolactone is used to support color, flavor, and oxidation stability.
Delta-Gluconolactone is used to bind calcium, iron, and other polyvalent ions under suitable conditions.
Delta-Gluconolactone is used to reduce the catalytic effect of trace metals.
Delta-Gluconolactone is used to improve stability in formulations sensitive to metal contamination.
Delta-Gluconolactone is used in combination with other chelating agents when greater sequestration is required.
Delta-Gluconolactone is used to inhibit discoloration caused by metal ions.
Delta-Gluconolactone is used to reduce oxidative flavor deterioration.
Delta-Gluconolactone is used in products containing sensitive colors and flavor compounds.
Delta-Gluconolactone is used after verifying its effect at the formulation pH.
Delta-Gluconolactone is used as a formulation aid.
Delta-Gluconolactone is used to control the timing of pH-sensitive reactions.
Delta-Gluconolactone is used where gradual conversion to gluconic acid supports processing.
Delta-Gluconolactone is used to improve uniformity in large-scale mixing operations.
Delta-Gluconolactone is used in protein-isolation processes.
Delta-Gluconolactone is used to precipitate proteins at or near their isoelectric point.
Delta-Gluconolactone is used in plant-protein fractionation.
Delta-Gluconolactone is used to produce protein curds and gels with controlled texture.
Delta-Gluconolactone is used in pea-protein formulations.
Delta-Gluconolactone is used in fava-bean and legume-protein systems.
Delta-Gluconolactone is used in alternative-protein foods.
Delta-Gluconolactone is used after evaluating flavor, texture, and mineral interactions.
Delta-Gluconolactone is used in meat-alternative formulations.
Delta-Gluconolactone is used to acidify plant-protein emulsions.
Delta-Gluconolactone is used to support gelation and textural development.
Delta-Gluconolactone is used in combination with salts, hydrocolloids, and thermal processing.
Delta-Gluconolactone is used in encapsulated and controlled-release food systems.
Delta-Gluconolactone is used where water activation initiates gradual acid generation.
Delta-Gluconolactone is used to separate acid-sensitive ingredients during dry storage.
Delta-Gluconolactone is used in powdered formulations requiring good shelf stability.
Delta-Gluconolactone is used in effervescent tablets.
Delta-Gluconolactone is used as an acid component with bicarbonate or carbonate salts.
Delta-Gluconolactone is used to support controlled carbon-dioxide release after contact with water.
Delta-Gluconolactone is used in food, supplement, and pharmaceutical effervescent systems.
Delta-Gluconolactone is used in pharmaceutical formulations.
Delta-Gluconolactone is used as a pH-adjusting and formulation-support ingredient.
Delta-Gluconolactone is used in oral and topical products when a suitable pharmaceutical grade is selected.
Delta-Gluconolactone is used only after excipient compatibility and stability testing.
Delta-Gluconolactone is used in pharmaceutical tablets and powders.
Delta-Gluconolactone is used in effervescent dosage forms.
Delta-Gluconolactone is used in oral formulations requiring gradual acidification.
Delta-Gluconolactone is used in products manufactured to applicable pharmacopoeial standards.
Delta-Gluconolactone is used in mineral and electrolyte preparations.
Delta-Gluconolactone is used as a precursor for gluconate salts.
Delta-Gluconolactone is used in reactions producing calcium, magnesium, iron, zinc, and other gluconates.
Delta-Gluconolactone is used in pharmaceutical and nutritional chemistry after purity control.
Delta-Gluconolactone is used in calcium-gluconate production.
Delta-Gluconolactone is used in sodium-gluconate production.
Delta-Gluconolactone is used in potassium- and magnesium-gluconate production.
Delta-Gluconolactone is used where controlled hydrolysis supplies gluconic acid for neutralization.
Delta-Gluconolactone is used in personal-care formulations under the INCI name Gluconolactone.
Delta-Gluconolactone is used as a polyhydroxy acid in skin-care products.
Delta-Gluconolactone is used as a mild exfoliating and skin-conditioning ingredient.
Delta-Gluconolactone is used in cosmetic products after safety and irritation assessment.
Delta-Gluconolactone is used in facial serums.
Delta-Gluconolactone is used in moisturizers and facial creams.
Delta-Gluconolactone is used in toners and treatment lotions.
Delta-Gluconolactone is used in leave-on products requiring gentle acidification.
Delta-Gluconolactone is used in products for dry or sensitive skin.
Delta-Gluconolactone is used in formulations where stronger alpha-hydroxy acids may be unsuitable.
Delta-Gluconolactone is used to support skin-surface hydration.
Delta-Gluconolactone is used to improve the appearance of rough or uneven skin.
Delta-Gluconolactone is used in anti-aging cosmetic formulations.
Delta-Gluconolactone is used in products intended to improve surface smoothness.
Delta-Gluconolactone is used in formulations targeting dullness and uneven texture.
Delta-Gluconolactone is used at concentrations appropriate to product type and intended contact time.
Delta-Gluconolactone is used in cosmetic peels.
Delta-Gluconolactone is used in rinse-off exfoliating products.
Delta-Gluconolactone is used in masks and treatment pads.
Delta-Gluconolactone is used only after evaluating final pH, free-acid concentration, and skin tolerance.
Delta-Gluconolactone is used in cleansers.
Delta-Gluconolactone is used in facial washes and cleansing gels.
Delta-Gluconolactone is used to regulate pH in surfactant systems.
Delta-Gluconolactone is used to provide mild polyhydroxy-acid functionality in rinse-off products.
Delta-Gluconolactone is used in shampoos and scalp-care products.
Delta-Gluconolactone is used to adjust formulation pH.
Delta-Gluconolactone is used in conditioning and treatment products after compatibility testing.
Delta-Gluconolactone is used to support product stability through controlled metal-ion binding.
Delta-Gluconolactone is used as a chelating ingredient in cosmetic formulations.
Delta-Gluconolactone is used to reduce the effect of trace metal ions on product stability.
Delta-Gluconolactone is used to support preservative and antioxidant systems.
Delta-Gluconolactone is used in combination with sodium benzoate and other approved preservation ingredients.
Delta-Gluconolactone is used in natural and naturally positioned preservation systems.
Delta-Gluconolactone is used to lower pH gradually within aqueous personal-care formulations.
Delta-Gluconolactone is used to improve the performance environment of pH-dependent preservatives.
Delta-Gluconolactone is used only after microbiological challenge testing of the finished formulation.
Delta-Gluconolactone is used in deodorants.
Delta-Gluconolactone is used to regulate pH in water-based deodorant products.
Delta-Gluconolactone is used in roll-on, cream, and spray formulations after compatibility testing.
Delta-Gluconolactone is used to support preservation and odor-control systems.
Delta-Gluconolactone is used in oral-care products.
Delta-Gluconolactone is used as a pH-adjusting or sequestrating component.
Delta-Gluconolactone is used in toothpaste and mouth-rinse formulations after oral-safety evaluation.
Delta-Gluconolactone is used to bind trace metal ions and support formulation stability.
Delta-Gluconolactone is used in soaps and cleansing bars.
Delta-Gluconolactone is used to reduce alkalinity in compatible cleansing formulations.
Delta-Gluconolactone is used in syndet bars and mild cleansing systems.
Delta-Gluconolactone is used to adjust processing and finished-product pH.
Delta-Gluconolactone is used in household cleaning formulations.
Delta-Gluconolactone is used as a biodegradable acidifying and chelating component.
Delta-Gluconolactone is used to reduce mineral deposits in selected aqueous cleaners.
Delta-Gluconolactone is used in formulations requiring controlled acidity.
Delta-Gluconolactone is used in hard-surface cleaners.
Delta-Gluconolactone is used in bathroom and kitchen cleaning products.
Delta-Gluconolactone is used to assist removal of alkaline residues and mineral scale.
Delta-Gluconolactone is used after evaluating material compatibility with stone, metal, grout, and coatings.
Delta-Gluconolactone is used in laundry and dishwashing formulations.
Delta-Gluconolactone is used as a sequestrating and pH-control component.
Delta-Gluconolactone is used to reduce the impact of water-hardness ions.
Delta-Gluconolactone is used in combination with other builders and chelating agents.
Delta-Gluconolactone is used in industrial cleaning products.
Delta-Gluconolactone is used to generate gluconic acid gradually in aqueous systems.
Delta-Gluconolactone is used for controlled removal of selected mineral deposits.
Delta-Gluconolactone is used only after corrosion and substrate-compatibility testing.
Delta-Gluconolactone is used in concrete and construction-chemical research.
Delta-Gluconolactone is used as a set-modifying or chelating component in selected cementitious systems.
Delta-Gluconolactone is used to influence metal-ion availability and hydration behavior.
Delta-Gluconolactone is used only after full-scale evaluation of setting time and strength.
Delta-Gluconolactone is used in textile-processing formulations.
Delta-Gluconolactone is used as a gradual acid donor in selected dyeing and finishing baths.
Delta-Gluconolactone is used to control pH during temperature-dependent textile processes.
Delta-Gluconolactone is used after fiber-, dye-, and bath-specific evaluation.
Delta-Gluconolactone is used in leather-processing formulations.
Delta-Gluconolactone is used to provide gradual acidification during selected process stages.
Delta-Gluconolactone is used to control pH more uniformly than direct strong-acid addition.
Delta-Gluconolactone is used after evaluating hide quality and process compatibility.
Delta-Gluconolactone is used as a laboratory reagent.
Delta-Gluconolactone is used as a source of gluconic acid in aqueous reaction systems.
Delta-Gluconolactone is used in carbohydrate and lactone chemistry.
Delta-Gluconolactone is used in biochemical and analytical research.
Delta-Gluconolactone is used in buffer and pH-control studies.
Delta-Gluconolactone is used in controlled protein-precipitation experiments.
Delta-Gluconolactone is used in studies of gradual acidification and gel formation.
Delta-Gluconolactone is used in laboratory work at a purity appropriate to the analytical method.
Delta-Gluconolactone is used as an intermediate in gluconate chemistry.
Delta-Gluconolactone is used to prepare metal gluconates.
Delta-Gluconolactone is used to prepare gluconic-acid derivatives.
Delta-Gluconolactone is used in specialty synthesis requiring a highly functional carbohydrate-derived lactone.
Delta-Gluconolactone is used in commercial formulations after grade-specific testing.
Delta-Gluconolactone is used according to its intended food, pharmaceutical, cosmetic, or technical grade.
Delta-Gluconolactone is used at concentrations established through product-development and stability studies.
Delta-Gluconolactone is used according to applicable technical, safety, and regulatory documentation.
DESCRIPTION
Delta-Gluconolactone is the cyclic 1,5-intramolecular ester of D-gluconic acid.
Delta-Gluconolactone is chemically identified as D-glucono-1,5-lactone.
Delta-Gluconolactone is an aldonic-acid lactone derived from D-glucose.
Delta-Gluconolactone contains multiple hydroxyl groups and one cyclic ester group.
Delta-Gluconolactone has the molecular formula C6H10O6.
Delta-Gluconolactone has a molecular weight of approximately 178.14 g/mol.
Delta-Gluconolactone has CAS number 90-80-2.
Delta-Gluconolactone has EC number 202-016-5.
Delta-Gluconolactone is generally supplied as white crystals or white crystalline powder.
Delta-Gluconolactone is odorless or nearly odorless.
Delta-Gluconolactone has a mildly sweet initial taste followed by increasing acidity in aqueous systems.
Delta-Gluconolactone is a solid under normal ambient conditions.
Delta-Gluconolactone is freely soluble in water.
Delta-Gluconolactone is sparingly soluble in ethanol.
Delta-Gluconolactone is practically insoluble in many nonpolar organic solvents.
Delta-Gluconolactone dissolves readily when added to properly agitated aqueous formulations.
Delta-Gluconolactone hydrolyzes after contact with water.
Delta-Gluconolactone converts gradually into D-gluconic acid.
Delta-Gluconolactone establishes an equilibrium containing gluconic acid and delta- and gamma-lactone forms.
Delta-Gluconolactone develops acidity progressively rather than instantaneously.
Delta-Gluconolactone hydrolysis rate depends on temperature.
Delta-Gluconolactone hydrolysis rate depends on solution pH.
Delta-Gluconolactone hydrolysis rate depends on concentration and the surrounding formulation.
Delta-Gluconolactone acidification behavior should be evaluated under actual processing conditions.
Delta-Gluconolactone provides an initially mild taste because the dry lactone is not fully converted to gluconic acid.
Delta-Gluconolactone becomes more acidic as hydrolysis proceeds.
Delta-Gluconolactone can therefore delay the perception and technological effects of acidity.
Delta-Gluconolactone is particularly valuable where controlled acid release is required.
Delta-Gluconolactone is produced from gluconic acid.
Delta-Gluconolactone may be prepared by direct crystallization from concentrated aqueous gluconic-acid solution.
Delta-Gluconolactone gluconic-acid feedstock is commonly produced through oxidation or fermentation of D-glucose.
Delta-Gluconolactone commercial production commonly uses carbohydrate-derived renewable feedstocks.
Delta-Gluconolactone food-grade material contains not less than approximately 99.0% active substance on a dried basis.
Delta-Gluconolactone food-grade material commonly has loss on drying of not more than approximately 1.0%.
Delta-Gluconolactone food-grade material commonly has sulfated ash of not more than approximately 0.1%.
Delta-Gluconolactone must satisfy applicable purity limits for reducing substances and trace contaminants.
Delta-Gluconolactone commonly melts with decomposition at approximately 150–160°C.
Delta-Gluconolactone should not be exposed unnecessarily to high processing temperatures while dry.
Delta-Gluconolactone may darken or decompose under severe thermal conditions.
Delta-Gluconolactone does not have a conventional flash point as a nonvolatile crystalline solid.
Delta-Gluconolactone is nonvolatile under normal storage conditions.
Delta-Gluconolactone is not considered readily flammable.
Delta-Gluconolactone can decompose in a fire to produce carbon oxides and irritating fumes.
Delta-Gluconolactone should be kept away from uncontrolled heat and ignition sources.
Delta-Gluconolactone aqueous solutions are acidic.
Delta-Gluconolactone solution pH decreases progressively during hydrolysis.
Delta-Gluconolactone final acidity depends on concentration, temperature, and buffering capacity.
Delta-Gluconolactone dosage should be selected according to the target final pH.
Delta-Gluconolactone can act as a sequestrant through the gluconic acid and gluconate formed during hydrolysis.
Delta-Gluconolactone interacts with calcium, iron, and other metal ions.
Delta-Gluconolactone can reduce the availability of metal ions that catalyze undesirable reactions.
Delta-Gluconolactone sequestration efficiency varies with pH and the competing components in the formulation.
Delta-Gluconolactone promotes protein coagulation by moving the system toward the protein isoelectric region.
Delta-Gluconolactone produces relatively uniform acidification throughout well-mixed protein systems.
Delta-Gluconolactone can create fine and smooth protein-gel structures.
Delta-Gluconolactone gelation performance depends on protein concentration, salts, temperature, and processing time.
Delta-Gluconolactone is recognized internationally as food additive INS 575.
Delta-Gluconolactone has the European food-additive designation E575.
Delta-Gluconolactone is classified by JECFA as an acidifier, raising agent, and sequestrant.
Delta-Gluconolactone has a JECFA group acceptable daily intake designated as not specified.
Delta-Gluconolactone is permitted for food uses only under applicable regional conditions.
Delta-Gluconolactone maximum-use levels or good-manufacturing-practice provisions depend on the food category.
Delta-Gluconolactone pharmaceutical uses require suitable compendial or pharmaceutical-grade material.
Delta-Gluconolactone cosmetic uses require appropriate purity, formulation, and safety evaluation.
Delta-Gluconolactone is available in food, pharmaceutical, cosmetic, laboratory, and technical grades.
Delta-Gluconolactone grades may differ in assay, particle size, bulk density, moisture, and trace impurities.
Delta-Gluconolactone should not be substituted between regulated applications without documentation.
Delta-Gluconolactone should be selected according to the current certificate of analysis and intended use.
PROPERTIES
Chemical Name: D-Glucono-1,5-Lactone
Common Name: Delta-Gluconolactone
Abbreviation: GDL
Food-Additive Number: E575
INS Number: 575
CAS Number: 90-80-2
EC Number: 202-016-5
PubChem CID: 7027
UNII: WQ29KQ9POT
Chemical Family: Sugar-acid lactones and aldonic-acid lactones
Chemical Type: Cyclic 1,5-intramolecular ester of D-gluconic acid
Molecular Formula: C6H10O6
Molecular Weight: 178.14 g/mol
Physical Form: Crystalline solid
Appearance: White crystals or white crystalline powder
Odor: Odorless or nearly odorless
Taste: Initially mildly sweet, becoming acidic after hydration
Water Solubility: Freely soluble
Ethanol Solubility: Sparingly soluble
Nonpolar-Solvent Solubility: Generally very low
Melting Behavior: Approximately 150–160°C with decomposition
Flash Point: Not applicable to the nonvolatile solid
Volatility: Very low
Combustibility: Not readily combustible under normal conditions
Aqueous Behavior: Gradual hydrolysis to D-gluconic acid
Hydrolysis Products: D-Gluconic acid and equilibrium quantities of delta- and gamma-lactones
JECFA Assay: Not less than 99.0% on a dried basis
Loss on Drying: Not more than approximately 1.0% under the JECFA specification
Sulfated Ash: Not more than approximately 0.1% under the JECFA specification
Solution pH: Concentration- and time-dependent because of progressive hydrolysis
Optical Activity: D-isomer and optically active
Primary Functions: Acidifier, acidity regulator, raising agent, sequestrant, curing agent, pickling agent, coagulant, pH-control agent, and formulation aid
FIRST AID
Inhalation:
Move the affected person to fresh air.
Obtain medical advice if dust causes persistent coughing or respiratory irritation.
Skin Contact:
Wash thoroughly with soap and water.
Seek medical advice if irritation persists.
Eye Contact:
Rinse cautiously with clean water for at least 15 minutes.
Remove contact lenses if easy to do and obtain medical attention if discomfort continues.
Ingestion:
Rinse the mouth and drink water if the person is conscious.
Obtain medical advice after significant accidental ingestion or if symptoms develop.
Note to Physicians:
Treat symptomatically and provide supportive care.
Consider the acidic character that develops after dissolution.
HANDLING AND STORAGE
Handling:
Avoid generating or inhaling dust and wear gloves and safety glasses.
Keep utensils and processing equipment clean and dry before use.
Ventilation:
Provide normal general ventilation and local dust extraction at transfer points.
Use particulate respiratory protection when airborne dust cannot be controlled.
Storage:
Store in tightly sealed moisture-resistant packaging in a cool and dry area.
Protect the product from humidity, contamination, excessive heat, and direct sunlight.
Spill and Leak Procedures:
Collect dry material without generating airborne dust.
Avoid washing large quantities directly into drains and clean wet residues promptly.
Handling Precautions:
Close opened packaging immediately because the material can absorb moisture and hydrolyze.
Follow the grade-specific technical data sheet, safety data sheet, and applicable food or pharmaceutical requirements.
