Quick Search

PRODUCTS

E 129

CAS Number: 25956-17-6 
EC Number: 247-368-0
Chemical Formula: C18H14N2Na2O8S2
Molar Mass: 496.42 g·mol−1

E 129 is an azo dye that widely used in drinks, juices, bakery, meat, and sweets products. 
High consumption of E 129 has claimed an adverse effects of human health including allergies, food intolerance, cancer, multiple sclerosis, attention deficit hyperactivity disorder, brain damage, nausea, cardiac disease and asthma due to the reaction of aromatic azo compounds (R = R 0 = aromatic). 

Several countries have banned and strictly controlled the uses of E 129 in food and beverage products. 
This review paper is critically summarized on the available analytical and advanced methods for determination of E 129 and also concisely discussed on the acceptable daily intake, toxicology and extraction methods.

E 129 is a red azo dye that goes by several names, including FD&C Red 40.
E 129 is used as a food dye and has the E number E129.

E 129, a food colourant, is dark red and water-soluble powder or granules used in various applications, such as in drinks, syrups, sweets and cereals. 
E 129 has the ability to quench the intrinsic fluorescence of HSA through static quenching.

E 129 is a food azo dye. 
E 129 is a dark red powder or granules, that is soluble in water and insoluble in ethanol.

Uses of E 129:
E 129 is used as color additive in foods, drugs and cosmetics. 
E 129 is used as a food dye and has the E number E129. 

E 129 is a colorant.
E 129 has good stability to ph changes from ph 3 to 8, showing no appreciable change. 

E 129 has excellent solubility in water with a solubility of 22 g/100 ml at 25°c. 
E 129 has very good stability to light, fair to poor stability to oxidation, good stability to heat, and shows no appreciable change in stability in 10% sugar systems. 

E 129 has a yellowish-red hue and has a very good tinctorial strength. 
E 129 has very good compatibility with food components and is used in beverages, desserts, candy, confections, cereals, and ice cream. 
The common name of E 129 is allura red ac.

Common Uses of E 129:
E 129 can be used for coloring food, drugs, and cosmetics, including beverages, frozen treats, powder mixes, gelatin products, candies, icings, jellies, spices, dressings, sauces, baked goods and dairy products.

Cosmetic Uses of E 129:
E 129 is a red dye that goes by many different names, including Red 40, E 129 AC and food, drugs and cosmetics (FD&C) red no. 40. 
The types of products this dye may be used in are food, drugs and cosmetics, which of course makes up FD&C. 

As a cosmetic dye, E 129 is used to enhance the color of many makeup, hair care and oral healthcare products. 
This dye is also used in some red tattoo inks and has been known to cause irritation when inserted under the skin.

While there are several red dyes used in makeup products, E 129 is one of the most common. 
E 129 is frequently used to enhance the color of foundation, eye shadow, lipstick and other types of makeup. 

E 129 has been deemed safe to use around the eyes and is sometimes also used in eye liner and mascara. 
Since this dye is typically derived from petroleum, E 129 is not usually included in natural products or those designed for sensitive skin. 
Non-comedogenic makeup, however, can contain this ingredient as E 129 has not been found to clog pores.

E 129 is also used in various skin care, hair care and oral healthcare products. 
Consumers can find this dye in many of their lotions, shampoos, toothpastes, mouthwashes and other products. 

E 129 is not used to enhance the effectiveness of these products. 
Instead, this dye is used to alter the color of the product and make E 129 more attractive to consumers. 
Since cosmetics do not necessarily have to be red to contain this dye, E 129 is important to consult a product’s ingredients list to determine whether E 129 contains this substance.

While E 129 is generally believed to be safe for cosmetic use, E 129 has been known to cause irritation when applied to the skin. 
People who are sensitive to petroleum should exercise caution when using makeup or other products that contain E 129. 
If a user does experience a reaction, he or she should discontinue using E 129 and avoid cosmetics that contain E 129 in the future.

In addition to being used in makeup and other cosmetics, E 129 is also used in some tattoo inks. 
Most commonly, this dye appears in red, pink and other similarly colored ink. 

E 129 is not considered hypoallergenic, and some individuals might experience a negative reaction to the dye. 
Those who are sensitive to synthetic dyes should discuss this with the tattoo artist before applying a tattoo.

Applications of E 129:

E 129 has been used:
For the determination of fecal neutral sterols (FNS) in mice,
To evaluate E 129 developmental toxicity,
As a coloring reagent for observing the experimental performance of liquid-handling robot.

E 129 is usually supplied as its red sodium salt, but can also be used as the calcium and potassium salts. 
These E 129 salts are soluble in water. 

In solution, E 129s maximum absorbance lies at about 504 nm.: 921 
E 129, FD&C Red No. 40 is manufactured by coupling diazotized 5-amino-4-methoxy-2-toluenesulfonic acid with 6-hydroxy-2-naphthalene sulfonic acid.

E 129 is used as a consumable coloring agent.
E 129 is a popular dye used worldwide. 
Annual production in 1980 was greater than 2.3 million kilograms.

The European Union approves E 129 as a food colorant, but EU countries' local laws banning food colorants are preserved.
In the United States, E 129 is approved by the FDA for use in cosmetics, drugs, and food. 

When prepared as a lake E 129 is disclosed as Red 40 Lake or Red 40 Aluminum Lake. 
E 129 is used in some tattoo inks and is used in many products, such as cotton candy, soft drinks, cherry flavored products, children's medications, and dairy products. 

E 129 is occasionally used to dye medicinal pills, such as the antihistamine fexofenadine, for purely aesthetic reasons.
E 129 is by far the most commonly used red dye in the United States, completely replacing amaranth and also replacing erythrosine in most applications due to the negative health effects of those two dyes.

Physical Description of E 129:
E 129 occurs as a red-brown powder or granule. 
E 129 is a monoazo dye, consisting mainly of disodium 6-hydroxy-5-(2-methoxy-5-methyl-4-sulfonato-phenylazo)-2-naphthalene-sulfonate and subsidiary coloring matter together with sodium chloride and/or sodium sulfate as the principal uncolored components and may be converted to the corresponding aluminum lake.

Identifiers of E 129:
PubChem CID: 6093299
UNII: WZB9127XOA 
CompTox Dashboard (EPA): DTXSID4024436
ChEMBL: ChEMBL174821 
ChemSpider: 11588224
ECHA InfoCard: 100.043.047 
Appearance: Red powder
Melting point: > 300 °C (572 °F; 573 K)

Product Number: A0943
Molecular Formula / Molecular Weight: C18H14N2Na2O8S2 = 496.42  
Physical State (20 deg.C): Solid
CAS RN: 25956-17-6
Reaxys Registry Number: 11336170
PubChem Substance ID: 87562448
Merck Index (14): 284
MDL Number: MFCD00059526

Empirical Formula (Hill Notation): C18H14N2Na2O8S2
CAS Number: 25956-17-6
Molecular Weight: 496.42
Colour Index Number: 16035
EC Number: 247-368-0
MDL number: MFCD00059526
PubChem Substance ID: 24869338
NACRES: NA.47

Properties of E 129:
Molecular Weight: 496.4     
Hydrogen Bond Donor Count: 1     
Hydrogen Bond Acceptor Count: 10     
Rotatable Bond Count: 3     
Exact Mass: 495.99869632     
Monoisotopic Mass: 495.99869632     
Topological Polar Surface Area: 185 Ų 
Heavy Atom Count: 32      
Complexity: 809 
Isotope Atom Count: 0     
Defined Atom Stereocenter Count: 0 
Undefined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0     
Undefined Bond Stereocenter Count: 0     
Covalently-Bonded Unit Count: 3     
Compound Is Canonicalized: Yes     

SMILES string: [Na+].[Na+].COc1cc(c(C)cc1N=Nc2c(O)ccc3cc(ccc23)S([O-])(=O)=O)S([O-])(=O)=O
InChI: 1S/C18H16N2O8S2.2Na/c1-10-7-14(16(28-2)9-17(10)30(25,26)27)19-20-18-13-5-4-12(29(22,23)24)8-11(13)3-6-15(18)21;;/h3-9,21H,1-2H3,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2/b20-19+;;
InChI key: CEZCCHQBSQPRMU-LLIZZRELSA-L

Names of E 129:

Preferred IUPAC name of E 129:
Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate

Other names of E 129:
Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonate
Allura Red
Food Red 17
C.I. 16035
FD&C Red 40
E129
2-Naphthalenesulfonic acid, 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-, disodium salt
Allura Red AC
25956-17-6
Allura Red
Allura red AC dye
C.I. Food Red 17
Food red 17
Food Red No. 40
FD&C Red No. 40
Curry red
ALLURA RED C.I.16035
UNII-WZB9127XOA
CI 16035
Red No. 40
FD and C Red No. 40
FD & C Red no. 40
WZB9127XOA
E129
MFCD00059526
2-Naphthalenesulfonic acid, 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-, disodium salt
CI 16035; Food Red 17; Fancy Red;
Fancy Red
Disodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalenesulfonate
Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate
Allura Red 40
FDC Red 40
CHEMBL174821
Japan Food Red No. 40
Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonate
2-Naphthalenesulfonic acid, 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt
sodium (E)-6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate
C.I.16035
ALLURAREDAC
Japan Red 40
CCRIS 3493
HSDB 7260
EINECS 247-368-0
Red 40
E 129
al-lura red ac
C. I. 16035
2-Naphthalenesulfonic acid, 6-hydroxy-5-(2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl)-, sodium salt (1:2)
2-Naphthalenesulfonic acid, 6-hydroxy-5-[2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-, sodium salt (1:2)
disodium 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
disodium;6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
DSSTox_CID_4436
FD and C Red No.40
Disodium 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-2-naphthalenesulfonate
EC 247-368-0
2-Naphthalenesulfonic acid, 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-, disodium salt
DSSTox_RID_77395
DSSTox_GSID_24436
SCHEMBL324089
SCHEMBL340786
C18H14N2Na2O8S2
CHEMBL3188816
DTXSID4024436
CHEBI:172687
Allura Red AC, analytical standard
Allura Red AC, Dye content 80 %
Tox21_300393
AKOS015903081
AKOS025310826
Disodium 6-hydroxy-5-((2-methoxy-4-sulphonato-m-tolyl)azo)naphthalene-2-sulphonate
Disodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalene- sulfonate
Allura Red AC 100 microg/mL in Water
NCGC00254423-01
6-Hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalene- sulfonic acid, disodium salt
BP-31017
T592
CAS-25956-17-6
A0943
F0325
FT-0661496
D70160
Q419895
J-016192
disodium;6-hydroxy-5-[(2-methoxy-5-methyl-4-sulonatophenyl)diazenyl]naphthalene-2-sulonate
disodium;(5Z)-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)hydrazinylidene]-6-oxonaphthalene-2-sulfonate
disodium;6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
1-[(6-Methoxy-4-sulfo-m-tolyl)azo]-2-naphthol-6-sulfonic Acid Disodium Salt
2-Naphthalenesulfonic acid, 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt
2-naphthalenesulfonic acid, 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt
2-Naphthalenesulfonic acid, 6-hydroxy-5-[(E)-2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-, sodium salt (1:2) [ACD/Index Name]
6-Hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonic Acid Disodium Salt
6-Hydroxy-5-[(6-methoxy-4-sulfo-m-tolyl)azo]-2-naphthalenesulfonic Acid Disodium Salt
6-Hydroxy-5-[(E)-(2-méthoxy-5-méthyl-4-sulfonatophényl)diazényl]-2-naphtalènesulfonate de disodium [French] [ACD/IUPAC Name]
Allura Red AC
C.I. Food Red 17
Dinatrium-6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]-2-naphthalinsulfonat [German] [ACD/IUPAC Name]
Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonate
Disodium 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]-2-naphthalenesulfonate [ACD/IUPAC Name]
Disodium 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
FD & C Red no. 40
FD&C Red No. 40
MFCD00059526
2-Naphthalenesulfonic acid, 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-, disodium salt
2-Naphthalenesulfonic acid, 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-, disodium salt
Allura Red
al-lura red ac
Allura Red AC (C.I. 16035)
Allura Red AC (E 129)
Allura Red AC (E129)
Allura Red AC 100 µg/mL in Water
Allura Red AC Dye
ALLURA RED C.I.16035
ALLURAREDAC
Colour Index, Food Red 17
disodium 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonato-phenyl)azo]naphthalene-2-sulfonate
FD & C Red No 40
FD and C Red No. 40
Food Red 17
Food Red No. 40
QK2260000
sodium (E)-6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate
Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate

Synonyms of E 129:
2-naphthalene sulfonic acids and derivatives 
Naphthols and derivatives 
Benzenesulfonic acids and derivatives 
1-sulfo,2-unsubstituted aromatic compounds 
Benzenesulfonyl compounds 
Methoxyanilines 
Anisoles 
Phenoxy compounds 
Methoxybenzenes 
Toluenes 
1-hydroxy-2-unsubstituted benzenoids 
Alkyl aryl ethers 
Organosulfonic acids 
Sulfonyls 
Azo compounds 
Propargyl-type 1,3-dipolar organic compounds 
Hydrocarbon derivatives 
Organopnictogen compounds 
Organic oxides 
2-naphthalene sulfonic acid or derivatives
2-naphthalene sulfonate
2-naphthol
Benzenesulfonate
Arylsulfonic acid or derivatives
Benzenesulfonyl group
1-sulfo,2-unsubstituted aromatic compound
Methoxyaniline
Anisole
Phenoxy compound
Phenol ether
Methoxybenzene
Alkyl aryl ether
1-hydroxy-2-unsubstituted benzenoid
Toluene
Monocyclic benzene moiety
Organic sulfonic acid or derivatives
Sulfonyl
Organosulfonic acid
Organosulfonic acid or derivatives
Azo compound
Ether
Propargyl-type 1,3-dipolar organic compound
Organic 1,3-dipolar compound
Organopnictogen compound
Organosulfur compound
Organooxygen compound
Organonitrogen compound
Organic oxygen compound
Organic oxide
Organic nitrogen compound
Hydrocarbon derivative
Aromatic homopolycyclic compound
 

  • Share !
E-NEWSLETTER