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E 160E

CAS Number : 1107-26-2 
EC  Number : 214-171-6
ECHA InfoCard    : 100.012.883 
PubChem CID    : 5478003
ChemSpider    : 4585625
Chemical formula :     C30H40O
Molar mass     :      416.649 g·mol−1

IUPAC name : 
-8′-Apo-β-caroten-8′-al

Preferred IUPAC name : 
-(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-Tetramethyl-17-(2,6,6-trimethylcyclohex-1-en-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal

Other names : 
-trans-beta-apo-8'-carotenal
-C.I. Food Orange 6
-E number 160E

E 160e, or trans-β-apo-8'-carotenal, is a carotenoid found in spinach and citrus fruits. 
Like other carotenoids, E 160e plays a role as a precursor of vitamin A, even though it has 50% less pro-vitamin A activity than β-carotene. 
The empirical chemical formula for E 160e is C30H40O.

E 160e has an orange to orange-red colour and is used in foods, pharmaceuticals and cosmetic products. 
Depending on the product forms, E 160e is used in fat based food (margarine, sauces, salad dressing), beverages, dairy products and sweets. 
Its E number is E160e and it is approved for usage as a food additive in the US, EU and Australia and New Zealand.

Possible carcinogenicity of E 160e
Epidemiological studies have shown that people with high E 160e intake and high plasma levels of E 160e have a significantly reduced risk of lung cancer . 
However, studies of supplementation with large doses of E 160e in smokers have shown an increase in cancer risk, possibly because excessive E 160e results in breakdown products that reduce plasma vitamin A and worsen the lung cell proliferation induced by smoke . 
The chief E 160e breakdown product suspected of this behavior is trans-beta-apo-8'-carotenal , which has been found in one study to be mutagenic and genotoxic in cell cultures which do not respond to E 160e itself.

E 160e is a natural product found in Dracaena draco, Palisota barteri, and other organisms with data available.
E 160e is an apo carotenoid triterpenoid compound arising from oxidative degradation of the beta,beta-carotene skeleton at the 8'-position. 
E 160e is an enal and an apo carotenoid triterpenoid.

E160e is a food additive approved by the European Union (EU). 
E160e is used as a synthetic colouring agent in food and drink products.

The common name for E160e is beta-apo-8'-carotenal (C30).
E160e is an orange / red colouring and although synthetic when used as a food additive, also occurs naturally in tangerines and oranges. 
E160e is soluble in oil.
Frequent high doses of E160e may discolour the skin.

Examples of food and drink products that sometimes include E160e:
-processed cheese
-citrus fruits

E160e is a carotenoid found in spinach and citrus fruits. 
Ours is a nature identical colorant that gives a light orange to orange-red hue. 
E160e can be used in dairy products, confectionery, ice cream, bakery, salty, sauces and beverages. 
Excellent heat and light stability.

E160e (or trans-β-apo-8'-carotenal) is an orange-red colored pigment found in citrus fruits and green vegetables. 
E160e ’s ideal for use in foods like processed cheese and beverages – and compared to certain natural pigments, offers you ease-of-use and superior color stability.
As the company responsible for the world’s first commercial synthesis of E160e  (and the global leader in carotenoid production), we have the experience and capabilities to help make your products healthier, more attractive - and more profitable.
Our vast assortment of color choices can be formulated into your applications (singly or mixed). 
They are tailor-made to meet your exact product specifications and address common challenges of supply, cost, quality, application and regulatory requirements. 
And they are available in liquid and powder form - depending on your target application.

E160e, or trans-beta-apo-8'-carotenal, is a carotenoid found in spinach and citrus fruits. 
Like other carotenoids, E160e plays a role as a precursor of vitamin A, even though it has 50% less pro-vitamin A activity than beta-carotene. 
The empirical chemical formula for E160e is C30H40O.

E160e has an orange to orange-red colour and is used in foods, pharmaceuticals and cosmetic products. 
Depending on the product forms, E160e is used in fat based food (margarine, sauces, salad dressing), beverages, dairy products and sweets. 
Its E number is 160E.

E160e, or trans-β-apo-8'-carotenal, is a carotenoid found in spinach and citrus fruits. 
Like other carotenoids, E160e plays a role as a precursor of vitamin A, even though it has 50% less pro-vitamin A activity than β-carotene. 
The empirical chemical formula for E160e is C30H40O.

E160e is a tetraterpenoid pigment that belongs to the group of carotenoids. 
Along with E160e, it is regarded as a precursor to vitamin A and is responsible for the orange-red color of fruits and vegetables. 
E160e is also known to show anti-oxidant and anti-carcinogenic properties.

Application of E160e 
-The analytical standards can also be used as follows:
-Simultaneous quantification of five carotenoids and two chlorophylls from soybean flour samples by reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with UV-Vis detector
-Profiling of carotenoids and their isomers in different plant tissue samples by high-performance liquid chromatography (HPLC) using a C30 column and photodiode array (PDA) detection
-Development and validation of a high-performance liquid chromatography-UV/Vis detection method for the determination of four carotenoids— α-carotene, β-carotene, α-cryptoxanthin, and β-cryptoxanthin, in oil obtained from P. conoideus
-Multi-residue determination of carotenoids in two algal species, isolated from saline water by HPLC coupled with a photodiode array detector
-Ultra-high performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS) method-based quantitative analysis of carotenoids in microalgae and rosehip extract samples

E160e  is a carotenoid available in citrus fruits and some vegetables such as spinach. 
Like beta-carotene, in the human body it transforms into Vitamin A. 
While beta-carotene contributes yellow to orange hues, apocarotenal contributes orange to red hues. 
Nature-identical apocarotenal coloring is relatively heat stable but degrades with light exposure.

E160e  is a carotenoid found in spinach and citrus fruits. 
E160e  is a nature-indentical colorant that gives a light orange to orange-red hue to a large range of food and beverage products. 
E160e  can be used in dairy, confectionery, ice cream, bakery, savory, sauces and beverages. 
E160e  is excellent stability to the light and heat.

Substance identity

EC / List no.: 214-171-6
CAS no.: 1107-26-2
Mol. formula: C30H40O

Hazard classification & labelling of E 160e
According to the majority of notifications provided by companies to ECHA in CLP notifications no hazards have been classified.

E 160e predicted as likely to meet criteria for category 1A or 1B carcinogenicity, mutagenicity, or reproductive toxicity, or with dispersive or diffuse use(s) where predicted likely to meet any classification criterion for health or environmental hazards, or where there is a nanoform soluble in biological and environmental media.
E 160e indicated, in 2009, as being intended to be registered by at least one company in the EEA.

E 160e for which classification and labeling data have been submitted to ECHA in a registration under REACH or notified by manufacturers or importers under CLP. 
Such notifications are required for hazardous substances, as such or in mixtures, as well as for all substances subject to registration, regardless of their hazard.
E 160e listed in the EINECS, ELINCS, or NLP inventories.


Synonyms:
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6E,8E,10E,12E,14E,16E)-
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
8'-Apo-beta-caroten-8'-al
8'-Apo-beta-carotenal
8'-Apo-beta-carotenal, all-trans-
8'-apo-ß-caroten-8'-al
8'-apo-β-caroten-8'-al
8'-apo-β-caroten-8'-al
8'Apo-beta,psi-carotenal
all-trans-beta-Apo-8'-carotenal
Apocarotenal
beta-Apo-8'-carotenal (C30)
beta-apo-Carotenal
C Orange 16
C.I. Food Orange 6
CI 40820
CI Food Orange 5
E160E
Food orange 6
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexenyl)heptadeca-2,4,6,8,10,12,14,16-octaenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohexen-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal
2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohex-1-en-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal
8'-apo-.beta.-Caroten-8'-al
8'-apo-beta-caroten-8'-al
8'-apo-β-caroten-8'-al
1107-26-2
2756-57-2
4172-46-7
Apocarotenal
1107-26-2
8'-Apo-beta-carotenal
beta-apo-8'-carotenal
C.I. Food Orange 6
8'-Apo-beta-caroten-8'-al
beta-apo-Carotenal
C Orange 16
beta-Apocarotenal
Food orange 6
8'Apo-beta,psi-carotenal
trans-beta-Apo-8'-carotenal
beta-Apo-8'-carotenal (C30)
all-trans-beta-Apo-8'-carotenal
BETA-APO-8'-CAROTENAL (TRANS)
all-trans-8'-apo-beta-carotenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohexen-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal
.beta.-apo-8'-Carotenal
CI 40820
Beta-apo-8'-carotenal(trans)
8'-apo-beta,psi-caroten-8'-al
V22N3E2U32
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6E,8E,10E,12E,14E,16E)-
8'-Apo-beta,psi-carotenal
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
CCRIS 7933
E160E
E 160 e
8'-Apo-beta-carotenal, all-trans-
EINECS 214-171-6
BRN 2064131
UNII-V22N3E2U32
C.I. 40820
8'-Apoaldehyde
8'-APO-.BETA.,.PSI.-CAROTENAL
trans-b-apo-8'-carotenal
trans-?-Apo-8?-carotenal
APOCAROTENAL [MART.]
4-07-00-01782 (Beilstein Handbook Reference)
APOCAROTENAL [USP-RS]
INS NO.160E
SCHEMBL341809
INS-160E
SCHEMBL2768511
trans- beta -Apo-8'-carotenal
CHEBI:53154
8'-apo-.beta.-Caroten-8'-al
DTXSID20883251
8'-APO-.BETA.-CAROTENAL
CAROTENAL, BETA-APO-8'-
CI 40820 [INCI]
HY-N6677
ZINC4521156
BETA-APO-8-CAROTENAL(TRANS)
E-160E
NSC374897
AKOS024386366
BETA-APO-8'-CAROTENAL [FCC]
NSC-374897
NCGC00187588-01
LS-15286
XA167402
CI(1975)NO.40820
CS-0099621
S5846
C19728
trans-beta-Apo-8'-carotenal, >=96.0% (UV)
Q274972
J-002468
beta-Apo-8-carotenal, 20 Percent Suspension in Corn Oil
Apocarotenal, United States Pharmacopeia (USP) Reference Standard
trans-beta-Apo-8'-carotenal, ~20% apocarotenal basis (UV-vis), suspension (oily)
(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-Tetramethyl-17-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8,10,12,14,16-heptadecaoctaenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohex-1-enyl)heptadeca-2,4,6,8,10,12,14,16-octaenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-Tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8,10,12,14,16-heptadecaoctaenal [ACD/IUPAC Name]
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-Tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8,10,12,14,16-heptadecaoctaenal [German] [ACD/IUPAC Name]
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-Tétraméthyl-17-(2,6,6-triméthyl-1-cyclohexén-1-yl)-2,4,6,8,10,12,14,16-heptadécaoctaénal [French] [ACD/IUPAC Name]
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-Tetramethyl-17-(2,6,6-trimethylcyclohex-1-en-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal
1107-26-2 [RN]
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (2E,4E,6E,8E,10E,12E,14E,16E)- [ACD/Index Name]
214-171-6 [EINECS]
8'-Apo-β-carotenal
all-trans-8'-apo-β-carotenal
all-trans-β-Apo-8'-carotenal
Apocarotenal [Wiki]
C.I. Food Orange 6
Colour Index, Food Orange 6
MFCD00042626
trans-β-Apo-8′-carotenal
trans-β-Apo-8'-carotenal
V22N3E2U32
β-apo-Carotenal
β-Apocarotenal
&β;-<i>apo</i>-8'-carotenal
<i>all-trans&lt;/i>-8'-apo-&amp;β;-carotenal
<i>all-trans&lt;/i>-8'-apo-&amp;β;-carotenal|&amp;β;-<i>apo&lt;/i>-8'-carotenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexenyl)heptadeca-2,4,6,8,10,12,14,16-octaenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohex-1-enyl)heptadeca-2,4,6,8,10,12,14,16-octaenal
(2E,4E,6E,8E,10E,12E,14E,16E)-2,6,11,15-tetramethyl-17-(2,6,6-trimethylcyclohexen-1-yl)heptadeca-2,4,6,8,10,12,14,16-octaenal
?????????-??-??????????????????
??-apo-8'-carotenal
2,4,6,8,10,12,14,16-Heptadecaoctaenal, 2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
2,4,6,8,10,12,14,16-Heptadecaoctaenal,2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,(2E,4E,6E,8E,10E,12E,14E,16E)-
2,6,11,15-tetramethyl-17-(2,6,6-trimethyl-1-cyclohexenyl)heptadeca-2,4,6,8,10,12,14,16-octaenal
2756-57-2 [RN]
4-07-00-01782 [Beilstein]
4-07-00-01782 (Beilstein Handbook Reference) [Beilstein]
4172-46-7 [RN]
8'-apo-&β;-carotenal
8'-apo-??-caroten-8'-al
8'-Apoaldehyde
8'-Apoaldehyde (Apocarotenal)
8'-apo-β-caroten-8'-al
8'-apo-β,ψ-caroten-8'-al
8'Apo-β,ψ-carotenal
8'-Apo-β,ψ-carotenal
8'-APO-β,ψ-CAROTENAL
8'-apo-β-caroten-8'-al
8'-Apo-β-caroten-8'-al
8'-Apo-β-carotenal, all-trans-
C Orange 16
C004984
-carotenal
E 160 e
E160E
EINECS 214-171-6
Food orange 6
trans-??-apo-8???-carotenal
trans-??-apo-8-carotenal
trans-8'-apo-β-Caroten-8'-al
trans-β-Apo-8'-carotenal
trans-β-Apo-8&#8242
trans-β-apo-8′-carotenal
UNII:V22N3E2U32
UNII-V22N3E2U32
β-Apo-8??-Carotenal
β-apo-8'-Carotenal
β-Apo-8'-carotenal
β-Apo-8'-carotenal (C30)
β-APO-8-CAROTENAL(TRANS)


 

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