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E1518, also known as triacetin, is an organic chemical compound used in the food, pharmaceutical, cosmetic, and chemical industries.
E1518 Glyceryl Triacetate is a colorless, oily liquid primarily used as a flavor carrier, solvent, plasticizer, and humectant.
E1518 Glyceryl Triacetate helps improve the texture of food products and reduce moisture loss.
CAS Number: 102-76-1
CBNumber: CB7441695
Chemical Formula: C9H14O6
Molecular Weight: 218.2 g/mol
MDL Number: MFCD00008716
MOL File: 102-76-1.mol
E Number: E1518
MAIN CHEMICAL SYNONYMS
Glyceryl Triacetate,
Glyceryl Triacetate,
Triacetin, Triacetate,
FEMA 2007,
Glycerin Triacetate,
Glyceryl Triacetate (Triacetin),
Vanay,
Enzactin,
Fungacetin
GENERAL INFORMATION
Triacetin is the triester of glycerol and acetic acid, also represented by the structural formula C3H5(OCOCH3)3.
Its chemical names include 1,2,3-propanetriol triacetate and 1,2,3-triacetoxypropane.
E1518 Glyceryl Triacetate is a triacylglycerol derivative produced by acetylating the three hydroxyl groups of glycerol.
In the food industry, E1518 Glyceryl Triacetate is identified by the code E1518 and is used as a flavor carrier, solvent, and softening agent.
E1518 Glyceryl Triacetate is a colorless liquid with low to moderate viscosity and an oily character.
The pure product is generally described as odorless or having a mild characteristic, fruity odor.
At low concentrations, E1518 Glyceryl Triacetate may have a mildly sweet taste, while higher concentrations may produce a bitter taste.
CHEMICAL STRUCTURE AND PRODUCTION
E1518 Glyceryl Triacetate is produced by esterifying glycerol with acetic acid or acetylating agents such as acetic anhydride.
Production methods include the reaction of glycerol with acetic anhydride and esterification processes using suitable catalysts.
Alternative production routes may use allyl acetate, acetic acid, oxygen, and appropriate catalysts.
The manufacturing process may involve reaction, purification, and distillation steps.
Product purity and physical properties depend on the manufacturing method and final purification conditions.
CHEMICAL AND PHYSICAL PROPERTIES
Triacetin is an organic compound with a high boiling point and a low melting point.
E1518 Glyceryl Triacetate has limited but measurable solubility in water and is miscible with ethanol and many other organic solvents.
Its solvent, plasticizing, and moisture-retaining properties make it useful in various industrial formulations.
E1518 Glyceryl Triacetate may also be used as a stationary-phase component or solvent in certain chromatographic applications.
APPLICATIONS
FOOD AND BEVERAGE INDUSTRY
E1518 Glyceryl Triacetate is used in the food industry as a flavor carrier and solvent.
Glyceryl Triacetate (Triacetin) can help carry and distribute aromatic compounds in alcoholic and non-alcoholic beverages.
In bakery products, confectionery, and certain desserts, it may help retain moisture and improve texture.
Glyceryl Triacetate (Triacetin) can be used as a softening agent and plasticizer in chewing gum.
The permitted concentration in food depends on the product category and applicable regulations.
COSMETIC INDUSTRY
Triacetin may be used in cosmetic formulations as a solvent, plasticizer, and component of certain antimicrobial systems.
Glyceryl Triacetate (Triacetin) helps carry fragrance ingredients and adjust formulation properties in perfumes, lotions, and other personal care products.
Its concentration in cosmetic products varies according to product type and formulation requirements.
The safety of the finished product should be assessed for potential skin and eye irritation.
PHARMACEUTICAL INDUSTRY
E1518 Glyceryl Triacetate is used as a plasticizer in polymer coatings for tablets, capsules, beads, and granules.
Glyceryl Triacetate (Triacetin) helps improve coating flexibility and integrity.
E1518 Glyceryl Triacetate may serve as an excipient or solvent in certain pharmaceutical formulations.
Glyceryl Triacetate (Triacetin) has also been investigated in controlled-release drug delivery systems and biodegradable gel formulations.
TOBACCO INDUSTRY
Triacetin is used as a plasticizer in the manufacture of cellulose acetate cigarette filter rods.
E1518 Glyceryl Triacetate helps bind filter fibers together and adjust the physical properties of the filter structure.
INDUSTRIAL APPLICATIONS
E1518 Glyceryl Triacetate may be used as a solvent in paint, ink, and coating formulations.
E1518 Glyceryl Triacetate can serve as a fixative or carrier component in fragrance and flavor formulations.
In some analytical applications, particularly chromatography, it may be used as a solvent or stationary-phase component.
Its potential use as an anti-knock agent in fuel formulations and as an additive to improve the low-temperature properties of biodiesel has also been investigated.
POTENTIAL APPLICATIONS
Triacetin has been studied in drug delivery systems and biodegradable formulations designed for controlled drug release.
In some experimental studies, E1518 Glyceryl Triacetate has been incorporated into gel systems intended to provide controlled delivery of drugs such as paclitaxel to targeted tissues.
E1518 Glyceryl Triacetate has also been considered as a potential energy source for closed-loop food systems designed for long-duration space missions.
These applications are experimental or specialized and require separate safety and performance assessments.
CHEMICAL PROPERTIES
Chemical Name: Glyceryl Triacetate
Other Name: Triacetin
Chemical Class: Glycerol triester
Molecular Formula: C9H14O6
Molecular Weight: 218.2 g/mol
Appearance: Clear, colorless liquid
Odor: Odorless or mildly characteristic, fruity odor
Taste: Mildly sweet or bitter
Solubility: Limited solubility in water; miscible with ethanol and various organic solvents
Flammability: May be combustible and requires appropriate safety precautions.
PHYSICAL PROPERTIES OF TRIACETIN
Melting Point: Approximately 3 °C
Boiling Point: Approximately 258-260 °C
Density: Approximately 1.16 g/mL at 25 °C
Vapor Density: Approximately 7.52 relative to air
Vapor Pressure: Depends on the temperature specified in the source
Refractive Index: Approximately n25/D 1.429-1.431
Flash Point: May vary according to the source and test method
Storage Conditions: In a suitable closed container under manufacturer-recommended conditions
Form: Liquid
Color: Clear and colorless
pH: Depends on the measurement conditions in the aqueous system
Biological Source: Generally synthetic
Odor Type: Fruity
JECFA Number: 920
FEMA Number: 2007
Merck Index: 14,9589
BRN: 1792353
MANUFACTURING METHODS
Triacetin can be prepared by esterifying glycerol with acetic acid or acetic anhydride.
Some methods use acid catalysts or suitable resin catalysts.
After production, the crude product may undergo purification steps such as neutralization, drying, and distillation.
Industrial production conditions vary according to the required purity and manufacturing technology.
ANALYTICAL DETERMINATION
Triacetin content can be determined using appropriate analytical methods.
One example involves hydrolyzing the sample with potassium hydroxide and titrating the excess alkali with standard sulfuric acid.
This procedure should be performed using an appropriate blank test and a validated analytical method.
Temperature, reaction time, reagent concentration, and sample quantity must be controlled during analysis.
SAFETY AND REGULATORY STATUS
Triacetin is an additive used in certain food applications.
In the United States, Triacetin is associated with GRAS status under specified conditions of use.
However, permitted applications and quantities may differ by country and product category.
Current food, pharmaceutical, and cosmetic regulations should be checked before use.
Some experimental studies have reported skin or eye irritation.
Safety assessments should consider concentration, route of exposure, and intended use.
SAFETY PROFILE
Harmful effects may occur if the substance is swallowed or used improperly.
Eye contact may cause irritation.
Keep away from heat, open flames, and strong oxidizing agents.
Heating or decomposition may release irritating fumes.
In the event of a fire, use an appropriate extinguishing agent and personal protective equipment.
Store the product in accordance with the manufacturer's safety data sheet and storage instructions.
STORAGE
Triacetin should be stored in a suitable, tightly closed container under the temperature and environmental conditions specified by the manufacturer.
Keep E1518 Glyceryl Triacetate away from direct heat sources, flames, and strong oxidizing agents.
For product purity and stability, follow the storage conditions stated in the technical data sheet.
NOTE
Physical properties, solubility values, flash point, and safety classifications may vary depending on the source, measurement method, and product purity.
The latest manufacturer technical data sheet and safety data sheet should be used as the primary references for product specifications.
CONTACT ATAMAN KIMYA
For further information, technical specifications, product quality details, and supply inquiries regarding E1518 Glyceryl Triacetate (Triacetin), please contact Ataman Kimya.
