E1518 Triacetin, chemically known as 1,2,3-triacetoxypropane, is an artificial organic compound used widely across the food, pharmaceutical, and chemical industries.
E1518 Triacetin is a triglyceride obtained by the acetylation of the three hydroxy groups of glycerol, typically deriving from an acetic acid or other acetylating agents (like acetic anhydride).
CAS No.102-76-1
Chemical Name:Triacetin
CBNumber:CB7441695
Molecular Formula:C9H14O6
Molecular Weight:218.2
MOL File:102-76-1.mol
Synonyms: GLYCEROL TRIACETATE,GLYCERYL TRIACETATE,Triacetine,triacetate,FEMA 2007,GLYCERIN TRIACETATE,Glyceryl Triacetate (Triacetin),Vanay,Enzactin,Fungacetin
E1518 Triacetin is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.
E1518 Triacetin is a colorless, viscous and odorless liquid at standard temperature and pressure (STP) with a high boiling point and a low melting point.
E1518 Triacetin has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
E1518 Triacetin is one of the glycerine acetate compounds.
E1518 Triacetin is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
E1518 Triacetin has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.
E1518 Triacetin has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.
E1518 Triacetin derives from an acetic acid.
E1518 Triacetate is a triester of glycerin and acetic acid that occurs naturally in papaya.
E1518 Triacetate is mainly used as a synthetic flavoring agent in ice-creams, nonalcoholic beverages and baked goods.
E1518 Triacetate, also known as triacetin and numbered E1518, is an organic chemical compound used as a food additive.
E1518 Triacetate is a colorless, oily liquid with a faint, characteristic odor, used mainly as a flavor carrier and softening agent in the food industry.
E1518 Triacetate is obtained by acetylation of glycerol and is valued for its ability to improve the texture and extend the shelf life of food products.
E1518 Triacetate, also known as 1,2,3-propanetriol triacetate or glyceryl triacetate, is the triester of glycerin and acetic acid.
E1518 Triacetate can be prepared by heating glycerin with acetic anhydride alone or in the presence of finely divided potassium hydrogen sulfate.
E1518 Triacetate can also be prepared by the reaction of oxygen with a liquid-phase mixture of allyl acetate and acetic acid using a bromide salt as a catalyst.
E1518 Triacetin, chemically known as Triacetin or glyceryl triacetate, is a synthetic food additive produced by the esterification of glycerol with acetic acid.
E1518 Triacetin belongs to the group of humectants and solvents and is approved in the European Union under the E-number 1518.
E1518 Triacetin is a colorless, slightly oily liquid with a mild, faintly fatty and acetic odor.
Chemical Profile & Nomenclature
The triglyceride 1,2,3-triacetoxypropane is more generally known in the chemical industry as triacetin, glycerin triacetate, or 1,2,3-triacetylglycerol.
Chemical Nature: E1518 Triacetin is one of the glycerine acetate compounds, specifically the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.
E1518 Triacetin is chemically obtained by the acetylation of the three hydroxy groups of glycerol and derives from an acetic acid.
Physical State: E1518 Triacetin is a colorless, viscous, and odorless liquid at standard temperature and pressure (STP) featuring a high boiling point and a low melting point.
Organoleptic Properties: E1518 Triacetin exhibits a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
Uses
E1518 Triacetin is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.
E1518 Triacetin is used as an excipient in pharmaceutical products, where E1518 Triacetin is used as a humectant, a plasticizer, and as a solvent.
The plasticizing capabilities of triacetin have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel.
In the study, triacetin was combined with PTX, ethanol, a phospholipid and a medium chain triglyceride to form a gel-drug complex.
This complex was then injected directly into the cancer cells of glioma-bearing mice.
The gel slowly degraded and facilitated sustained release of PTX into the targeted glioma cells.
Uses
As a plasticizer and fragrance fixative, ink solvent, also used in medicine and dye synthesis.
As a chromatographic fixative, solvent, toughener and fragrance fixative.
Humectants; carrier solvents; plasticizers;E1518 Glycerol Triacetate can absorb carbon dioxide from the natural gas.
In the production of cosmetics, pharmaceuticals and dyes, plasticizers for cigarette filter rods, and so on.
Applied in cosmetics, casting, medicine, dyes and other industries.
This product is non-toxic, non-irritating.
As the substrate for the determination of lipase, perfume fixative, solvent, gas chromatographic fixative (maximum temperature of 85 ℃, solvent: methanol, chloroform), separation of gas and aldehyde analysis.
Uses
E1518 Triacetate is a colorless, oily liquid of slight fatty odor and bitter taste.
E1518 Triacetate is soluble with water and is miscible with alcohol and ether.
E1518 Triacetate functions in foods as a humectant and solvent.
As fixative in perfumery; solvent in manufacture of celluloid, photographic films.
Technical triacetin (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing.
E1518 Triacetate, a component of cigarette filters, induced a contact dermatitis in a worker at a cigarette manufacturers.
Uses
As a plasticizer and fragrance fixative, ink solvent, also used in medicine and dye synthesis.
As a chromatographic fixative, solvent, toughener and fragrance fixative.
Humectants; carrier solvents; plasticizers; E1518 Triacetin can absorb carbon dioxide from the natural gas.
In the production of cosmetics, pharmaceuticals and dyes, plasticizers for cigarette filter rods, and so on.
Applied in cosmetics, casting, medicine, dyes and other industries. This product is non-toxic, non-irritating.
As the substrate for the determination of lipase, perfume fixative, solvent, gas chromatographic fixative (maximum temperature of 85 ℃, solvent: methanol, chloroform), separation of gas and aldehyde analysis.
Use in Food
In the food industry, E1518 is primarily used as a solvent for flavorings.
E1518 Triacetate improves the solubility and stability of flavor compounds in food products and ensures their even distribution.
Typical applications include:
Chewing gum: As a plasticizer in the gum base
Flavorings and flavoring preparations: As a carrier and solvent
Baked goods and confectionery: To improve texture and shelf life
Non-alcoholic beverages: As a solvent for flavorings
Production
E1518 Triacetin can be derived from the esterification of glycerol and acetic acid.
After preheating glycerol to 50-60 ° C, add acetic acid, benzene and sulfuric acid.
Heat and stir for refluxing dehydration, and recycle the benzene.
Then add acetic anhydride for heating of 4h.
After cooling, the mixture was neutralized with 5% sodium carbonate to pH 7, and the crude layer was dried and the crude oil was dried with calcium chloride.
Distill under reduced pressure, collect the 128-131 ° C (0.93 kPa) fraction, namely glycerol triacetate.
Physical and Chemical Properties
Appearance and Odor: E1518 Triacetin is a colorless, viscous, and odorless liquid at standard temperature and pressure (STP).
Thermal Attributes: E1518 Triacetin features a high boiling point and a low melting point, making E1518 Triacetin exceptionally stable across a wide temperature range.
Taste Profile: In low concentrations (under 500 ppm),E1518 Triacetin has a mild, sweet taste, but E1518 Triacetin can become bitter at higher concentrations.
E1518 Triacetin Properties
Melting point: 3 °C(lit.)
Boiling point: 258-260 °C(lit.)
Density: 1.16 g/mL at 25 °C(lit.)
vapor density: 7.52 (vs air)
vapor pressure: 0.00248 mm Hg @ 250C
refractive index: n25/D 1.429-1.431(lit.)
FEMA: 2007 | (TRI-)ACETIN
Flash point: 300 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Soluble in water, miscible with ethanol (96 per cent) and toluene.
form: Liquid
color: Clear colorless
PH: 5.0-6.0 (20°C, 50g/L in H2O)
Odor: Characteristic odour
explosive limit: 1.05%, 189°F
biological source: synthetic
Odor Type: fruity
Water Solubility: 64.0 g/L (20 ºC)
Specific Heat Capacity: Cp(liquid): 1.76 J/(g·K), at 25℃
JECFA Number: 920
Merck: 14,9589
BRN: 1792353
Safety
The US Food and Drug Administration has approved E1518 Glycerol Triacetate as generally recognized as safe food additive and included E1518 Glycerol Triacetate in the database according to the opinion from the Select Committee On GRAS Substances (SCOGS).
E1518 Glycerol Triacetate is included in the SCOGS database since 1975.
E1518 Glycerol Triacetate was not toxic to animals in studies of exposure through repeated inhalation over a relatively short period.