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CAS NO:866-84-2
EC NO:212-755-5
E number:E332
E332 (Potassium citrate) (also known as tripotassium citrate) is a potassium salt of citric acid with the molecular formula K3C6H5O7.
E332 (Potassium citrate) is a white, hygroscopic crystalline powder.
E332 (Potassium citrate) is odorless with a saline taste.
E332 (Potassium citrate) contains 38.28% potassium by mass. In the monohydrate form, it is highly hygroscopic and deliquescent.
As a food additive, potassium citrate is used to regulate acidity, and is known as E number E332. Medicinally, it may be used to control kidney stones derived from uric acid or cystine.
Synthesis
E332 (Potassium citrate) can be synthesized by the neutralization of Citric acid which is achieved by the addition of Potassium bicarbonate, Potassium carbonate or Potassium hydroxide to it. The solution can then be filtered and the solvent can be evaporated till granulation.
Uses
E332 (Potassium citrate) is rapidly absorbed when given by mouth, and is excreted in the urine. Since it is an alkaline salt, it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine.
It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.
E332 (Potassium citrate) is an effective way to treat/manage gout and arrhythmia, if the patient is hypokalemic.
E332 (Potassium citrate) is widely used to treat urinary calculi (kidney stones), and is often used by patients with cystinuria.
E332 (Potassium citrate) is also used as an alkalizing agent in the treatment of mild urinary tract infections, such as cystitis.
E332 (Potassium citrate) is also used in many soft drinks as a buffering agent.
Frequently used in an aqueous solution with other potassium salts, it is a wet chemical fire suppressant that is particularly useful against kitchen fires.
E332 (Potassium citrate)s alkaline pH encourages saponification to insulate the fuel from oxidizing air, and the endothermic dehydration reaction absorbs heat energy to reduce temperatures.
Properties
Chemical formula K3C6H5O7
Molar mass 306.395 g/mol
Appearance white powder
hygroscopic
Odor odorless
Density 1.98 g/cm3
Melting point 180 °C (356 °F; 453 K)
Boiling point 230 °C (446 °F; 503 K)
Solubility in water soluble
Solubility soluble in glycerin
insoluble in ethanol (95%)
Acidity (pKa) 8.5
Uses
E332 (Potassium citrate) is used to make the urine less acidic. This effect helps the kidneys get rid of uric acid, thereby helping to prevent gout and kidney stones. E332 (Potassium citrate) can also prevent and treat certain metabolic problems (acidosis) caused by kidney disease.
Citric acid and citrate salts (which contain potassium and sodium) belong to a class of drugs known as urinary alkalinizers.
E332 (Potassium citrate) (also known as tripotassium citrate) is a potassium salt of citric acid.
E332 (Potassium citrate) is a white, hygroscopic crystalline powder.
E332 (Potassium citrate) is odorless with a saline taste.
E332 (Potassium citrate) contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent.
E332 (Potassium citrate) is used to treat a kidney stone condition called renal tubular acidosis.
Potassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis.
E332 (Potassium citrate) (anhydrous) is the anhydrous form of the tripotassium salt of citric acid.
E332 (Potassium citrate) has a role as a diuretic.
E332 (Potassium citrate) contains a citrate(3-).
E332 (Potassium citrate) anhydrous is a Metabolic Alkalinizer. The mechanism of action of potassium citrate anhydrous is as an Alkalinizing Activity.
Industry Uses
Surface active agents
Consumer Uses
Cleaning and furnishing care products
E332 (Potassium citrate) is used in foods, beverages, and technical applications as a buffering, sequestering or emulsifying agent.
E332 (Potassium citrate) usually replaces sodium citrate when low sodium content is desired.
E332 (Potassium citrate) can be used in a variety of beverage and pharmaceutical products.
E332 (Potassium citrate) is an important supplement for human health.
E332 (Potassium citrate) is a common treatment for the prevention of kidney stones.
The applications of potassium citrate (or tripotassium citrate) mainly derive from its alkaline properties.
E332 (Potassium citrate) is used to treat kidney stones composed of uric acid and cysteine, as well as other renal failures caused by excess acidity, including in veterinary applications. As an additive to soft drinks and other edibles, it also functions as an acid buffer, less bitter than other potassium salts, and with less sodium than trisodium citrate.
An additional use of potassium citrate is to supplement potassium in patients with hypokalemia, preventing and treating gout and arrhythmia.
Chemical properties
Colorless crystals or white crystalline powder, odorless, cool and salty, slight deliquescence, soluble in water and glycerin, insoluble in ethanol. Tests show that the product had no significant harm to the human body, ADI doesn’t need special provision.
Uses
As a preservative, stabilizing and pH buffering agents and others. China provides for various types of food, according to production needs to use appropriately.
Used in the food, pharmaceutical and other industries, as buffering agents, chelating agents, flavoring agents, stabilizers, antioxidants, emulsifying salts.
Production methods
Citric acid and potassium hydroxide or potassium bicarbonate derived products.
C6H8O7 + 3KHCO3 → CaH5K3O7 · H2O + 3CO2 ↑ + 2H2O
Description
E332 (Potassium citrate) is a potassium salt of citric acid with the molecular formula C6H5K3O7.
E332 (Potassium citrate) is a white, slightly hygroscopic crystalline powder.
E332 (Potassium citrate) is odorless with a saline taste.
As a food additive, potassium citrate is used to regulate acidity and is known as E number E332. Medicinally, it may be used to control kidney stones derived from either uric acid or cystine.
Chemical Properties
Colorless or white crystals or powder; cooling, saline taste; odorless; deliquescent. Soluble in water and glycerol; almost insoluble in alcohol.
Uses
E332 (Potassium citrate) is it acts as a buffer, maintaining product pH constant, a pH adjuster and a product stabilizer. This is a potassium salt.
Uses
For use as an electrolyte replenisher and in the treatment of hypokalemia.
Uses
E332 (Potassium citrate) is rapidly absorbed when given by mouth and is excreted in the urine. Since it is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine .
E332 (Potassium citrate) is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.
E332 (Potassium citrate) is an effective way to treat/manage gout and arrhythmia, if the patient is hypokalemic.
E332 (Potassium citrate) is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria .
Production Methods
E332 (Potassium citrate) is produced by adding potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases, filtering the solution and evaporating to granulation.
Definition
ChEBI: The anhydrous form of the tripotassium salt of citric acid.
Industrial uses
E332 (Potassium citrate) is used in the United Kingdom as an over-the-counter drug for the relief from discomfort experienced in mild urinary-tract infections by increasing the urinary pH.
E332 (Potassium citrate) should be not given to men if they experience pain in the kidney area (risk of kidney stones) or if blood or pus is present in the urine. Also, patients with raised blood pressure or diabetes should avoid taking potassium citrate without consultation with their general practitioner (GP). Caution is generally advised to patients with renal impairment, cardiac problems and the elderly.
E332 (Potassium citrate) tribasic solution is provided as a 1M solution in water. Used in the laboratory as a buffering agent and chelator.
E332 (Potassium citrate) is a white, slightly hygroscopic crystalline powder.
Properties: Odorless, taste of normal salt water, soluble in water, slowly soluble in glycerol, insoluble
Potassium Citrate can be used as stabilizer and pH buffer.
E332 (Potassium citrate) can be used in all kinds of food according to production needs. Medically, it can be used to control.
E332 (Potassium citrate) can be used to prevent hypokalemia and alkalize the urine.
Solubility of Potassium Citrate:
E332 (Potassium citrate) is soluble in water or glycerin, almost insoluble in ethanol.
Application:
E332 (Potassium citrate) can be used as a preservative, stabilizer and pH buffer.
E332 (Potassium citrate) can be used for all kinds of food, according to China's regulations, the production needs of the appropriate use.
A white, slightly hygroscopic crystalline powder, odorless with a saline taste.
Applications: treating gout, kidney stones, diuretic for animals
Molecular FormulaC6H5K3O7
Molecular Weight306.39
Purity≥98%
AppearanceWhite to off-white powder
Appearance: colorless crystal or white crystalline powder
Assay: 99%
Melting Point: 230°C
Boiling Point: 309.6°C at 760 mmHg
Flash Point: 155.2°C
Density: 1.87
Vapour Pressure: 5.73E-05mmHg at 25°C
E332 (Potassium citrate) is white or yellowish crystal or crystalline powder.
E332 (Potassium citrate) tastes salty and has slightly deliquescence.
E332 (Potassium citrate) is readily soluble in water or glycerine, and almost insoluble in ethanol (Relative density 1.98, it will melt and decompose when heated to 230°C) .
E332 (Potassium citrate) is also referred to by its IUPAC name as tripotassium citrate. E332 (Potassium citrate) is a salt resulting from citric acid and potassium.
E332 (Potassium citrate)s production is accomplished when either potassium carbonate or bicarbonate is added to a solution made of citric acid.
Potassium Citrate enjoys wide application in industries. In food industry, Potassium Citrate is used as buffering agent, chelating agent, stabilizer, emulsifier, flavouring agent, etc. Besides, it also can be applied to milk and dairy products, jellies, jam, meat, snacks. In the pharmaceutical industry, Potassium Citrate is used to treat hypokalemia and potassium deficiency and alkalize urine.
E332 (Potassium citrate) is colorless or white crystal or crystalline powder, odorless, taste salty, easy deliquescence, readily soluble in water or glycerin, almost insoluble in ethanol.
E332 (Potassium citrate) will melt and decompose when heated to 230°C.
E332 (Potassium citrate) having light hygroscopic property and ease to dissolve in water, slowly in glycerine, but not in alcohol. E332 (Potassium citrate) has a salty cool taste.
About this substance
Helpful information
Potassium Citrate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Potassium Citrate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
Potassium Citrate is used in the following products: fertilisers, biocides (e.g. disinfectants, pest control products), laboratory chemicals, adhesives and sealants, adsorbents, air care products, coating products, fillers, putties, plasters, modelling clay, inks and toners, pH regulators and water treatment products, perfumes and fragrances, photo-chemicals, polishes and waxes, textile treatment products and dyes, washing & cleaning products, water softeners, water treatment chemicals and cosmetics and personal care products.
Other release to the environment of Potassium Citrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Article service life
Release to the environment of Potassium Citrate can occur from industrial use: in the production of articles.
Other release to the environment of Potassium Citrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Potassium Citrate can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), wood (e.g. floors, furniture, toys), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and leather (e.g. gloves, shoes, purses, furniture).
Potassium Citrate is intended to be released from scented: paper products.
Widespread uses by professional workers
Potassium Citrate is used in the following products: laboratory chemicals, fertilisers, biocides (e.g. disinfectants, pest control products), adsorbents, air care products, coating products, fillers, putties, plasters, modelling clay, inks and toners, perfumes and fragrances, photo-chemicals, polishes and waxes, textile treatment products and dyes, washing & cleaning products, water softeners, water treatment chemicals and cosmetics and personal care products.
Potassium Citrate is used in the following areas: health services, building & construction work, agriculture, forestry and fishing, formulation of mixtures and/or re-packaging and mining.
Potassium Citrate is used for the manufacture of: machinery and vehicles and furniture.
Release to the environment of Potassium Citrate can occur from industrial use: formulation of mixtures, in processing aids at industrial sites and in the production of articles.
Other release to the environment of Potassium Citrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Formulation or re-packing
Potassium Citrate is used in the following products: fertilisers, air care products, polishes and waxes, washing & cleaning products, biocides (e.g. disinfectants, pest control products), laboratory chemicals, perfumes and fragrances, water softeners and water treatment chemicals.
Release to the environment of Potassium Citrate can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, manufacturing of the substance and formulation in materials.
Other release to the environment of Potassium Citrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Uses at industrial sites
Potassium Citrate is used in the following products: pH regulators and water treatment products, polishes and waxes, washing & cleaning products and water treatment chemicals.
Potassium Citrate is used in the following areas: mining, health services, building & construction work and formulation of mixtures and/or re-packaging.
Potassium Citrate is used for the manufacture of: machinery and vehicles, chemicals, electrical, electronic and optical equipment, metals, fabricated metal products and textile, leather or fur.
Release to the environment of Potassium Citrate can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, as processing aid and formulation of mixtures.
Other release to the environment of Potassium Citrate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Manufacture
Release to the environment of Potassium Citrate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials and in processing aids at industrial sites.
IUPAC names
potassium 2-hydroxypropane-1,2,3-tricarboxylate
E332 (Potassium citrate)
potassium citrates
tri potassium citrate
Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate
Tripotassium 3-hydroxy-3-carboxylate-1,5-pentanedicarboxylate
Tripotassium citrate
tripotassium citrate
Tripotassium Citrate
Tripotassium citrate
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
Trisodium citrate
SYNONYMS:
E332 (Potassium citrate) [Wiki]
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) [ACD/Index Name]
212-755-5 [EINECS]
2-hydroxypropane-1,2,3-tricarboxylate de tripotassium [French]
866-84-2 [RN]
86R1NVR0HW
Citrate de tripotassium [French] [ACD/IUPAC Name]
citric acid, potassium salt
Citric acid, tripotassium salt
Trikalium-2-hydroxypropan-1,2,3-tricarboxylat [German]
Trikaliumcitrat [German] [ACD/IUPAC Name]
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate
Tripotassium citrate [ACD/IUPAC Name]
UNII-86R1NVR0HW
[7778-49-6]
[866-84-2]
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt
6100-05-6 [RN]
citric acid potassium salt
Citric acid tripotassium salt
EINECS 212-755-5
EINECS 231-905-0
