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E578 Calcium Gluconate is the calcium salt of gluconic acid used in food and beverage applications as a firming agent, mineral fortifier, and acidity regulator in compatible systems, and E578 Calcium Gluconate is valued for providing calcium with relatively mild taste and good formulation flexibility.
E578 Calcium Gluconate helps supply calcium for nutritional fortification and can support texture and firmness in selected products, and E578 Calcium Gluconate is used in beverages, dairy, bakery, confectionery, and processed fruit and vegetable systems where controlled calcium addition is desired.
E578 Calcium Gluconate is typically supplied as a white crystalline powder or granules, often as a hydrate, and E578 Calcium Gluconate performance depends on purity, hydration state, solubility, dosage, and interactions with pH, phosphates, and gelling agents in the formulation.
CAS Number: 299-28-5
EC Number: 206-077-4
Molecular Formula: C12H22CaO14
Molecular Weight: 430.37 g/mol
Synonyms: E578 Calcium Gluconate, Calcium Gluconate, Gluconic Acid Calcium Salt, Calcium D-Gluconate, Calcium Gluconate Food Grade, E578, Calcium Gluconate Mineral Fortifier, Calcium Gluconate Firming Agent, Calcium Gluconate Powder, Calcium Gluconate Hydrate, Gluconate Calcium Salt, Calcium Gluconate Stabilizer, E578 Calcium Gluconate, Calcium Gluconate, D-Calcium Gluconate, Calcium D-Gluconate, Gluconic Acid Calcium Salt, D-Gluconic Acid Calcium Salt, Calcium Salt of Gluconic Acid, Calcium 2,3,4,5,6-Pentahydroxyhexanoate, Calcium Dextronic Acid Salt, Calcium Glyconate, E578 Food Additive, E578 Sequestrant, E578 Stabilizer, E578 Acidity Regulator, Calcium Gluconate Food Grade, Food Grade Calcium Gluconate, Calcium Gluconate Sequestrant, Calcium Gluconate Chelating Agent, Calcium Gluconate Complexing Agent, Calcium Gluconate Stabilizer, Calcium Gluconate Buffering Agent, Calcium Gluconate Processing Aid, Calcium Gluconate Food Additive, Calcium Gluconate Beverage Additive, Calcium Gluconate Reagent, Industrial Calcium Gluconate, Pharmaceutical Calcium Gluconate, Cosmetic Grade Calcium Gluconate, High Purity Calcium Gluconate, Calcium Gluconate Powder, Calcium Gluconate Granules, Calcium Gluconate Crystals, Calcium Gluconate FCC, Calcium Gluconate USP
APPLICATIONS
E578 Calcium Gluconate is used in fortified beverages in selected applications as a calcium source with mild taste profile.
E578 Calcium Gluconate is incorporated into functional drinks to increase calcium content while maintaining acceptable sensory performance in compatible formulations.
E578 Calcium Gluconate is used in beverage powders to deliver calcium after reconstitution when solubility and dispersion are controlled.
E578 Calcium Gluconate is used in dairy products in selected applications to increase calcium content and support nutritional positioning.
E578 Calcium Gluconate is incorporated into dairy-based beverages to improve calcium fortification while reducing harsh mineral taste compared with some calcium salts.
E578 Calcium Gluconate is used in yogurt-style products in selected applications where mineral balance and stability are carefully controlled.
E578 Calcium Gluconate is used in bakery and confectionery in selected applications to support calcium fortification and improve mineral content of finished goods.
E578 Calcium Gluconate is incorporated into nutrition bars to provide calcium in fortified formulations.
E578 Calcium Gluconate is used in lozenges and confectionery products in selected applications where calcium delivery is desired.
E578 Calcium Gluconate is used in processed fruits and vegetables in selected applications as a firming agent to support texture retention.
E578 Calcium Gluconate is incorporated into canned fruits and vegetables to help maintain firmness during heat processing and storage.
E578 Calcium Gluconate is used in fruit preparations and fillings to support texture stability in compatible systems.
E578 Calcium Gluconate is used in sauces and dressings in selected applications to manage calcium addition and support stability in compatible formulations.
E578 Calcium Gluconate is incorporated into functional foods where calcium contribution and mild acidity control are both desired.
E578 Calcium Gluconate is used in dietary supplement products as a calcium source in tablets, capsules, and powders.
E578 Calcium Gluconate is valued because E578 Calcium Gluconate provides calcium in a relatively mild-tasting, formulatable salt form that supports both nutritional fortification and selected firming or stability functions in food systems.
E578 Calcium gluconate is used as a calcium source in foods and beverages for mineral fortification in some formulations.
E578 Calcium gluconate supports calcium enrichment with good solubility compared with some calcium salts.
E578 Calcium gluconate helps improve nutritional labeling for calcium when used appropriately.
E578 Calcium gluconate is used in fortified beverages to supply calcium in some products.
E578 Calcium gluconate supports stable calcium addition in ready-to-drink beverages.
E578 Calcium gluconate helps reduce precipitation risk compared with less soluble calcium salts in some systems.
E578 Calcium gluconate is used in powdered drink mixes as a calcium source in some formulations.
E578 Calcium gluconate supports improved dissolution and uniform distribution in powders.
E578 Calcium gluconate helps improve consistency of fortified powder performance.
E578 Calcium gluconate is used in dairy alternatives to increase calcium content in some formulations.
E578 Calcium gluconate supports calcium fortification of plant-based milks in some designs.
E578 Calcium gluconate helps improve mineral balance and nutritional positioning in dairy analogs.
E578 Calcium gluconate is used in yogurt drinks and dairy beverages to increase calcium content in some products.
E578 Calcium gluconate supports mineral fortification while maintaining acceptable taste in some systems.
E578 Calcium gluconate helps reduce chalky mouthfeel compared with more insoluble calcium salts in some designs.
E578 Calcium gluconate is used in infant and pediatric nutrition in some contexts where mineral profiles are adjusted under strict standards.
E578 Calcium gluconate supports calcium balancing in controlled formulations.
E578 Calcium gluconate helps meet target mineral ratios in regulated nutrition products.
E578 Calcium gluconate is used in medical nutrition products to support calcium intake in some formulas.
E578 Calcium gluconate supports standardized calcium dosing in specialized nutrition.
E578 Calcium gluconate helps improve nutrition profiles in recovery and bone-support products.
E578 Calcium gluconate is used in dietary supplements as a calcium source in tablets and capsules.
E578 Calcium gluconate supports calcium fortification in mineral supplement blends.
E578 Calcium gluconate helps provide a calcium salt option with relatively good handling properties.
E578 Calcium gluconate is used in chewable supplements to deliver calcium in some products.
E578 Calcium gluconate supports consumer-friendly calcium delivery formats.
E578 Calcium gluconate helps improve compliance by offering non-capsule options.
E578 Calcium gluconate is used in effervescent tablets to provide calcium in some formulations.
E578 Calcium gluconate supports soluble calcium delivery in effervescent drinks.
E578 Calcium gluconate helps improve palatability versus some alternative calcium salts in some systems.
E578 Calcium gluconate is used in pharmaceutical products as a calcium salt for medical applications depending on market use.
E578 Calcium gluconate supports calcium administration in certain medical contexts.
E578 Calcium gluconate helps provide a bioavailable calcium form in controlled products.
E578 Calcium gluconate is used in oral care products to support formulation stability by chelating trace metals in some systems.
E578 Calcium gluconate supports improved performance in the presence of hard water minerals.
E578 Calcium gluconate helps reduce mineral film and supports cleaner mouthfeel in some formulations.
E578 Calcium gluconate is used in cosmetics as a stabilizing mineral salt in some formulations.
E578 Calcium gluconate supports ionic strength control and improved stability in some products.
E578 Calcium gluconate helps reduce discoloration caused by metal-catalyzed oxidation in some systems.
E578 Calcium gluconate is used in skin care to support gentle mineral fortification and improved mildness in some formulations.
E578 Calcium gluconate supports stability of sensitive ingredients by reducing metal stress in some systems.
E578 Calcium gluconate helps improve overall formulation robustness in some products.
E578 Calcium gluconate is used as a sequestrant in foods to bind trace metals and improve stability in some formulations.
E578 Calcium gluconate supports reduced oxidation catalyzed by iron and copper in some products.
E578 Calcium gluconate helps improve shelf life by slowing rancidity and color changes in some systems.
E578 Calcium gluconate is used in beverages to reduce haze caused by metal interactions in some formulations.
E578 Calcium gluconate supports improved clarity and reduced precipitation in some drinks.
E578 Calcium gluconate helps stabilize flavor and color by managing metal ion effects.
E578 Calcium gluconate is used in syrups and liquid flavor preparations to improve stability in some systems.
E578 Calcium gluconate supports metal management that reduces discoloration.
E578 Calcium gluconate helps improve long-term storage stability of liquid premixes.
E578 Calcium gluconate is used in household cleaners as a chelating agent to improve cleaning performance in some formulations.
E578 Calcium gluconate supports removal of limescale and mineral deposits in some cleaning systems.
E578 Calcium gluconate helps improve cleaning performance in hard water by binding interfering ions in some products.
E578 Calcium gluconate is used in dishwashing formulations to reduce spotting and film caused by hard water in some detergents.
E578 Calcium gluconate supports improved rinse performance in some products.
E578 Calcium gluconate helps reduce mineral redeposition on dishes and glass.
E578 Calcium gluconate is used in laundry detergents to support cleaning performance in hard water conditions in some formulations.
E578 Calcium gluconate supports improved surfactant performance by managing hardness ions.
E578 Calcium gluconate helps reduce dinginess and mineral buildup on fabrics in some systems.
E578 Calcium gluconate is used in industrial cleaning to support metal ion control in some applications.
E578 Calcium gluconate supports complexation behavior that can aid cleaning.
E578 Calcium gluconate helps improve cleaning efficiency while maintaining milder profiles in some systems.
E578 Calcium gluconate is used in water treatment to manage metal ions in some systems.
E578 Calcium gluconate supports improved stability of water-based formulations in some programs.
E578 Calcium gluconate helps reduce deposition and scaling tendency in some applications.
E578 Calcium gluconate is used in cement and concrete admixtures as a set modifier in some formulations.
E578 Calcium gluconate supports controlled hydration kinetics in cement systems.
E578 Calcium gluconate helps improve workability retention in some concrete applications.
E578 Calcium gluconate is used in gypsum and plaster formulations as a setting modifier in some applications.
E578 Calcium gluconate supports controlled set and improved workability.
E578 Calcium gluconate helps reduce premature setting in some construction mixes.
E578 Calcium gluconate is used in agriculture as a calcium source in some foliar and nutrient products.
E578 Calcium gluconate supports calcium delivery in liquid nutrient formulations.
E578 Calcium gluconate helps reduce precipitation risk compared with some calcium salts in hard water.
E578 Calcium gluconate is used in fertilizers to stabilize and deliver calcium in some formulations.
E578 Calcium gluconate supports improved compatibility in liquid fertilizer blends.
E578 Calcium gluconate helps reduce nozzle blockage caused by mineral precipitation.
E578 Calcium gluconate is used in fermentation and biotechnology as a mineral component in some media systems.
E578 Calcium gluconate supports calcium supply in controlled bioprocess environments.
E578 Calcium gluconate helps improve consistency of fermentation outcomes in some applications.
E578 Calcium gluconate is used in laboratory chemistry as a calcium source and complexation example.
E578 Calcium gluconate supports preparation of stable calcium solutions for testing.
E578 Calcium gluconate helps reduce unwanted precipitation in analytical procedures.
E578 Calcium gluconate is used in analytical chemistry as a reference compound and for method development in some assays.
E578 Calcium gluconate supports calibration and validation of mineral analysis tests.
E578 Calcium gluconate helps study complexation behavior of calcium under different pH conditions.
E578 Calcium gluconate is used in product development to optimize calcium fortification and stability in beverages and supplements.
E578 Calcium gluconate supports screening versus other calcium salts for taste and solubility.
E578 Calcium gluconate helps improve consumer acceptance of fortified products.
E578 Calcium gluconate is used in manufacturing troubleshooting to address haze, precipitation, and mineral instability problems.
E578 Calcium gluconate supports rapid correction of mineral-driven stability issues.
E578 Calcium gluconate helps improve robustness of production under variable water quality.
E578 Calcium gluconate is used in quality control to monitor calcium content and stability performance in finished products.
E578 Calcium gluconate supports consistent performance across batches.
E578 Calcium gluconate helps ensure specification compliance for mineral content and stability.
DESCRIPTION
E578 Calcium Gluconate is the calcium salt of gluconic acid, and E578 Calcium Gluconate is commonly produced by neutralizing gluconic acid with a calcium base followed by crystallization to food-grade specifications.
E578 Calcium Gluconate provides calcium ions, and calcium contributes to nutritional value and can also interact with pectins and other gelling agents to influence texture in fruit and vegetable systems.
E578 Calcium Gluconate has relatively mild taste compared with some calcium salts, and this makes E578 Calcium Gluconate useful for calcium fortification in sensitive flavor systems when solubility and clarity are properly managed.
E578 Calcium Gluconate solubility is moderate, and solubility depends on temperature and pH, so beverage applications often require careful formulation to prevent sedimentation or haze.
E578 Calcium Gluconate can interact with phosphates and some proteins, and these interactions can influence stability, so compatibility testing is important for each product.
E578 Calcium Gluconate should be used according to applicable food additive regulations and good manufacturing practices for the target market.
E578 Calcium Gluconate is typically supplied as a white crystalline powder or granules, often as a hydrate, and hydration state affects dosing calculations for calcium content.
E578 Calcium Gluconate should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and maintain consistent quality.
E578 Calcium Gluconate should be kept away from strong acids and strong oxidizers and stored under clean conditions to maintain food-grade integrity.
E578 Calcium gluconate is the calcium salt of gluconic acid and is used as a calcium source and stabilizing salt.
E578 Calcium gluconate is typically supplied as a white crystalline powder or granules with good water solubility compared with some calcium salts.
E578 Calcium gluconate provides calcium ions for fortification while the gluconate part can complex metal ions to improve stability in some systems.
E578 Calcium gluconate is used in foods, beverages, and supplements to deliver calcium and support stability in some formulations.
E578 Calcium gluconate is also used in some industrial systems for metal management and formulation stability where gluconate behavior is useful.
E578 Calcium gluconate performance depends on dosage, pH, ionic strength, and interactions with other salts and formulation components.
E578 Calcium gluconate should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and caking.
E578 Calcium gluconate is valued for soluble calcium delivery, relatively mild taste profile, and broad usefulness across nutrition and industrial applications.
PROPERTIES
Chemical Formula: C12H22CaO14
Molecular Weight: 430.37 g/mol
Common Name: E578 Calcium Gluconate
Chemical Type: Organic salt; mineral fortifier; firming agent (selected applications); acidity regulator (selected)
Appearance: White crystalline powder or granules
Odor: Odorless
Taste: Mild; slightly bitter or mineral note possible at higher concentrations
Solubility: Moderately soluble in water; solubility increases with temperature
Calcium Content: Grade dependent; hydrate form affects dosing calculations
pH Behavior: Slightly acidic to near neutral in solution (concentration dependent)
Stability: Stable under normal storage; compatible with many food processing conditions
Storage Temperature: 15–30°C, tightly closed, dry
Shelf Life: Typically 24–60 months in original sealed packaging (supplier dependent)
FIRST AID
Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during powder handling.
Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.
Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.
Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a large amount is swallowed.
Never give anything by mouth to an unconscious person.
Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care as needed.
HANDLING AND STORAGE
Handling:
Use appropriate PPE including gloves and safety glasses for bulk handling.
Avoid generating dust and avoid inhalation of fine powder.
Use clean, food-grade equipment for weighing and blending to prevent contamination.
Ventilation:
Use general ventilation for normal handling.
Use local exhaust where dust may be generated during powder transfer.
Minimize airborne particulate accumulation in enclosed areas.
Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain free-flowing behavior.
Keep containers properly labeled and protected from contamination.
Spill and Leak Procedures:
Sweep up spilled powder and avoid dust generation.
Collect into suitable containers for reuse or disposal according to local regulations.
Clean residues with water if needed and dry the area to prevent slip hazards.
Handling Precautions:
Optimize dosage because E578 Calcium Gluconate affects calcium level, firmness, and stability, and excessive levels can change taste, haze, or texture.
Consider formulation interactions because calcium can crosslink pectins and interact with phosphates and proteins, affecting texture and stability.
Rotate stock using FIFO practices to maintain consistent quality and predictable fortification and firming performance.
