PRODUCTS

ERYTHROSINE

Erythrosine is used as a food dye, in printing inks, as a biological stain, a dental plaque disclosing agent and a radiopaque medium.
Erythrosine is commonly used in sweets and foods marketed to children such as candies, popsicles, cake frosting, and cake-decorating gel.
Erythrosine is commonly used in candies, ice pops, cake-decorating gels, canned cherries, and some dairy products.

CAS Number: 16423-68-0
EC Number: 240-474-8
Molecular Formula: C₂₀H₆I₄Na₂O₅
Molecular Weight: 879.86 g/mol

SYNONYMS:
Eosin J,Pyrosin B,Iodeosin B,C.I. 45430,Erythrosine,ERYTHROSINE,Acid Red 51,ERYTHROSIN B,Erythrosin B,Erythrosine B,Food Red No.3,ERYTHROSINE B,C.I. Acid Red 51,C.I. Food Red 14,ERYTHROSIN BLUISH,ERYTHROSINE B STAIN,Erythrosine B disodium,ERYTHROSIN EXTRA BLUISH,Erythrosin extra bluish,ERYTHROSIN, DISODIUM SALT,ERYTHROSIN B, POLYMER BOUND,Tetraiodifluorescein, disodium salt,Erythrosine sodium (close form) [USAN],Erythrosin B, high purity biological stain,2',4',5',7'-Tetraiodofluorescein, disodium salt,disodium 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate,disodium 2',4',5',7'-tetraiodo-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate,2,4,5,7-Tetraiodo-3,6-dihydroxyxanthene-9-spiro-1'-3H-isobenzofuran-3'-one disodium salt,2',4',5',7'-Tetraiodo-3',6'-dihydroxy-spiro[3H-isobenzofuran-1,9'-xanthen]-3-one disodium salt,Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-, disodium salt,2-(6-Hydroxy-2,4,5,7-tetraiodo-3-oxo-xanthen-9-yl)benzoic acid,ERYTHROSINE,E127,3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one,FD & C red no. 3,3',6'-dihydroxy-2',4',5',7'-tetraiodospiro(2-benzofuran-3,9'-xanthene)-1-one,FDC Red No. 3,RefChem:591122,Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-, disodium salt,16423-68-0,Erythrosine, sodium anhydrous,NSC-36685,Erythrosin B,Tetraiodofluorescein,15905-32-5,Solvent Red 140,Iodeosin,Erythrosine acid,Erythrosine, phenolic,2',4',5',7'-Tetraiodofluorescein,2,4,5,7-Erythrosin,C20H8I4O5,Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-,Erythrosine B (free acid),C.I. Solvent Red 140,1A878FZQ9B,DTXSID7044843,MFCD00005044,NSC-328781,NCGC00166249-02,3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one,Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-2',4',5',7'-tetraiodo-,C.I. Food Red 14,DTXCID1024207,FD and C Red No. 3,SMR000857151,CAS-15905-32-5,EINECS 240-046-0,NSC 328781,BRN 0062817,UNII-1A878FZQ9B,Fluoresceins,Iodoeosine,Felumin,Ceplac,Trace,Dianthine B,Iodeosine B,Pyrosine B,Tetrajodfluorescein,12,15-dihydroxy-11,13,14,16-tetraiodospiro[3-hydroisobenzofuran-3,9'-xanthene] -1-one,3',6'-DIHYDROXY-2',4',5',7'-TETRAIODO-3H-SPIRO(2-BENZOFURAN-1,9'-XANTHEN)-3-ONE,Spiro[isobenzofuran-1(3H),9'-[9h]xanthen]-3-one,3',6'-dihydroxy-2',4',5',7'-tetraiodo-,E127 Erythrosine,Tetraiodofluoresceuin,Erythrosin Free Acid,2,5,7-Erythrosin,tetra-iodo-fluorescein,ERYTHROSINE J, Erythrosine B free acid,Cogilor orange 211.10,Cogilor orange 312.42,Fluorescein, 2',4',5',7'-tetraiodo- (VAN),2,5,7-Tetraiodofluorescein,SCHEMBL25042,4-19-00-02923 (Beilstein Handbook Reference),MLS001332405,MLS001332406,Red 1427,Solvent red 140; Iodoeosine,orb1310477,CHEMBL1332616,SCHEMBL29353687,SCHEMBL29356181,2',5',7'-Tetraiodofluorescein,2, 4,5,7-Tetraiodofluorescein,Fluorescein,4',5',7'-tetraiodo-,Tox21_113464,Tox21_301634,BDBM50542241,Erythrosin B, Dye content >=95 %,HB0759,NSC328781,SBB057757,STL453505,AKOS015903873,Tox21_113464_1,FE47102,3',6'-Dihydroxy-2',4',5',7'-tetraiodospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one,SMP2_000049,NCGC00166249-01,NCGC00166249-03,NCGC00256240-01,AS-74205,SY051638,HY-107864,CI 45430:2,CS-0030748,NS00005678,ST51006960,T0578,C.I. 45430:2,D92303,Q420101,Solvent Red 140; Tetraiodofluoresceuin; Erythrosine,Spiro[isobenzofuran-1(3H), 3',6'-dihydroxy-2',4',5',7'-tetraiodo-,3',6'-Dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[[2]benzofuran-1,9'-xanthen]-3-one,3',6'-Dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one,3',6'-dihydroxy-2',4',5',7'-tetraiodo-spiro[isobenzofuran-3,9'-xanthene]-1-one,3 inverted exclamation mark ,6 inverted exclamation mark -Dihydroxy-2 inverted exclamation mark ,4 inverted exclamation mark ,5 inverted exclamation mark ,7 inverted exclamation mark -tetraiodo-3H-spiro[isobenzofuran-1,9 inverted exclamation mark -xanthen]-3-one,3',6'-Dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'(9H)-xanthen]-3-one, 9CI,Erythrosine, FD&C Red No. 3, Red No. 3, Food Red 14, CI 45430, Acid Red 51, E127, Tetraiodofluorescein, Disodium 2',4',5',7'-tetraiodofluorescein

Erythrosine (Tetraiodofluorescein) is a cherry-pink coal-based fluorone food dye.
Erythrosine's maximum absorbance is at 530 nm in an aqueous solution, and it is subject to photodegradation.
Erythrosine (Powder), European permitted synthetic food color, is a free-flowing blendable water soluble dye powder, free from lumps or visible impurities.

Erythrosine has a pure dye content no lower than 87% and the C.I.
Erythrosine consists essentially of disodium 2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl) benzoate monohydrate and subsidiary colouring matters together with water, sodium chloride and/or sodium sulfate as the principal uncoloured components.

Erythrosine is described as the sodium salt.
The color index number of Erythrosine is 15430.
The chemical formula of Erythrosine is C20H6I4Na2O5.H2O and the molecular weight is 897,88.

Erythrosine, also known as E127 and Red No. 3, is an organoiodine compound, specifically a derivative of fluorone.
Erythrosine is a red-pink dye used for food coloring, cosmetics, hair coloring, pet products, and diverse industrial colorings.
Erythrosine is the disodium salt of 2,4,5,7-tetraiodofluorescein.

Erythrosine is a synthetic organoiodine dye belonging to the xanthene class of dyes.
Erythrosine produces a bright pink to cherry-red coloration and is especially notable for its high iodine content and strong fluorescence.
Erythrosine (FD&C Red No. 3 or E127) is a synthetic, cherry-pink organoiodine dye used for decades to color foods like maraschino cherries, candies, and icings.

Erythrosine is a tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of DENTAL PLAQUE, and as a stain of some cell types.
Erythrosine has structural similarity to THYROXINE.

Erythrosine occurs as a brown powder or granules.
Erythrosine is a xanthene dye, consisting of the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate monohydrate and subsidiary coloring matters.

Erythrosine gives a red colour to foods and beverages.
Erythrosine is known as F&DC Red No. 3, in the US and is approved by the Food and Drug Administration for use as a food colouring according to the US Food and Drug Administration (US-FDA)-1995.
Erythrosine, in the UK, is known as E127 and is restricted to only certain cocktails and syrup, according to the European Food Safety Authority (EFSA).

Erythrosine is a brown powder or granules of xanthene dye consisting of the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo xanthen-9 yl) benzoate monohydrate and subsidiary colouring elements.
Erythrosine is an artificial red organic agent containing iodine and sodium that is known to give a watermelon red to various food products, including medicines.
Erythrosine is a brown powder that forms a cherry red synthetic dye solution with water.

First discovered in 1876 by Kussamaul, erythrosine is an iodinate derivative of fluorescein.
Early use of erythrosine was as a direct dye on wool and silk.
Erythrosine was also used in inks, lacquers, cosmetics, and as a lake pigment.

However, because erythrosine was not colorfast in sunlight, its use as a textile dye was discontinued by the 1920s.
Erythrosine was approved as a food dye in 1906, and was popularly used in cherries, candies and cake decorating gels.
erythrosine B, also known as tetraiodofluorescein B, is a red or reddish brown particle or powder, odorless, soluble in water, soluble in ethanol, propylene glycol and glycerin, insoluble in oil.

Erythrosine has good staining, especially for protein staining.
Red Dye No. 3, also known by its chemical name Erythrosine or E127, is a synthetic dye derived from petroleum.
Erythrosine belongs to the xanthene dye family, which produces a bright cherry-red colour commonly used to enhance the visual appeal of food, drinks, and cosmetics.

Its vivid hue and stability under light have made Erythrosine a go-to additive in various products for decades.
Erythrosine is a tetraiodinated derivative of fluorescein.
Due to the presence of iodine atoms, Erythrosine exhibits strong coloration and fluorescence properties.

USES and APPLICATIONS of ERYTHROSINE:
Erythrosine (E 127) is used in the food industry to color foods and beverages.
Additionally, Erythrosine is used in the printing industry for ink manufacturing.
Erythrosine is used as a food dye, in printing inks, as a biological stain, a dental plaque disclosing agent and a radiopaque medium.

Erythrosine is commonly used in sweets and foods marketed to children such as candies, popsicles, cake frosting, and cake-decorating gel.
Erythrosine is commonly used in candies, ice pops, cake-decorating gels, canned cherries, and some dairy products.
Erythrosine was historically used to dye pistachio shells and is also used in dental plaque-disclosing agents.

Erythrosine is widely used in the food industry as a coloring agent, particularly in products such as candies, cake decorations, icings, gel-based desserts, and processed fruits like candied cherries.
Erythrosine is often chosen when a bright pink or red hue is desired.
In pharmaceuticals, Erythrosine is used to color tablets, capsules, and syrups, helping with product identification and aesthetic appeal.

In dentistry, erythrosine has a specialized application as a plaque disclosing agent, where it stains dental plaque to make it visible for diagnostic and educational purposes.
Erythrosine is also used in cosmetics, although its use may be restricted depending on regional regulations.
Additionally, erythrosine is utilized in certain analytical chemistry and biological staining procedures due to its fluorescence and staining capabilities.

From a functional standpoint, erythrosine enhances visual attractiveness, improves consumer perception, and ensures consistent coloration across batches.
Its strong tinting strength and water solubility make Erythrosine effective in low concentrations.
Erythrosine is widely used as a food colorant, pharmaceutical excipient, and cosmetic pigment.

Erythrosine provides a watermelon-red color and can be used in foods and pharmaceuticals, including baked goods, breakfast cereals, confectionery products, dairy products, decorations for baking, dressings and sauces, dried fruit, frostings and icings, frozen breakfast foods, frozen treats, hot beverages, juice drinks and processed fish, meat and egg products.
Erythrosine is used as a food coloring, printing ink, biological stain, dental plaque disclosing agent, radiopaque medium, sensitizer for orthochromatic photographic films, and visible light photoredox catalyst.

Erythrosine is commonly used in sweets, such as some candies, ice pops and cherries, and in cake-decorating gels.
Erythrosine was also used to color pistachio shells.
As a food additive, Erythrosine has the E number E127

Use of Erythrosine: Coloring for food, pharmaceuticals and cosmetics
Main applications of Erythrosine: color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy

Erythrosine is mainly used as plastic lubricant, suitable for thermoplastic and thermosetting plastics such as polyethylene, polypropylene, polystyrene, ABS resin, polyvinyl chloride, etc.
Erythrosine is used for coloring food, medicine and cosmetics.
Erythrosine is edible red pigment.

Erythrosine can be used for starch, baked goods, shrimp, ham, sausage, cherry, etc.
Erythrosine is often used with other pigments.
The dosage of Erythrosine is 5~100mg/kg.

As a food colorant, Erythrosine can be used in red and green silk and canned dyed cherries (for decoration), with a maximum usage of 0.10 g/kg.
Erythrosine is used in seasoning sauce, various beverages, prepared wine, candy, pastry coloring and green plum, the maximum usage is 0.05 g/kg.
Erythrosine is used as a red pigment.

Erythrosine is widely used in non-acidic foods such as fermented foods, baked foods, ice cream, fish cakes, pickled products, etc., and can also be used in conjunction with other food coloring.
Erythrosine is not for drinks and hard candy.
The usage amount of Erythrosine is 5~100mg/kg.

Erythrosine is used as an adsorption indicator for precipitation titration.
Erythrosine is used as an acid-base titration fluorescence indicator, pH greater than 2.5, no fluorescence, pH not less than 4.0, light green fluorescence.
Erythrosine is used as a photometric reagent.

Erythrosine is used as a biological stain.
Erythrosine is widely used in the food industry as a coloring agent, particularly in products like cherries, candies, baked goods, and snack foods.
Erythrosine provides a bright red hue that is visually appealing and consistent.

In pharmaceuticals, erythrosine is used to color tablets and capsules, improving product identification and consumer appeal.
Erythrosine is also used in dental disclosing tablets to highlight plaque on teeth, helping in oral hygiene education.
In cosmetics, Erythrosine is used in products such as lipsticks and blushes due to its vibrant color.

Additionally, erythrosine is used in biological staining and diagnostic applications because of its ability to bind to certain tissues.
Erythrosine is commonly used as a food dye, especially in products like candies, cake decorations, and processed foods.
Erythrosine is also utilized in pharmaceuticals for coating tablets and in diagnostic staining.

-Biological applications of Erythrosine:
Detecting gene expression, phosphoproteins, protease, stress biomarkers.
treating age-related macular degeneration, arteriosclerosis, bone metabolic diseases, burns, cancer, diabetes, human immunodeficiency virus infection, obesity

-Application of Erythrosine:
compared with other synthetic red pigments of the same type, its heat resistance, alkali resistance, oxidation-reduction resistance and tinting strength are better, so Erythrosine can be widely used in non-acidic foods such as fermented foods, baked foods, ice cream, fish cakes, pickled products, etc.

CHARACTERISTICS AND PROPERTIES of ERYTHROSINE:
Erythrosine is distinguished by its tetraiodinated structure, which significantly enhances its molecular weight and contributes to its intense coloration and fluorescence.
The presence of iodine atoms also affects its photophysical properties, making Erythrosine highly visible even at low concentrations.
Erythrosine exhibits strong light absorption and emission characteristics, which is why it is sometimes used in analytical and diagnostic applications.

Erythrosine has excellent water solubility due to its ionic nature, allowing it to disperse uniformly in aqueous systems.
However, Erythrosine is more sensitive to light compared to many other synthetic dyes, which can lead to gradual fading under prolonged exposure.
Its compatibility with a range of pH conditions makes Erythrosine suitable for various formulations.

BENEFITS of ERYTHROSINE:
Erythrosine offers high color intensity, excellent visibility, and strong fluorescence properties.
Erythrosine is effective at low dosages, making it cost-efficient in formulations.
Erythrosine's ability to produce a distinct and stable pink/red color is valuable in both food and pharmaceutical industries.
Erythrosine also provides functional benefits in dental and laboratory applications.

PHYSICAL AND CHEMICAL PROPERTIES of ERYTHROSINE:
Erythrosine appears as a reddish-pink crystalline powder or granules.
Erythrosine is highly soluble in water, forming a bright red solution, but only slightly soluble in alcohol and practically insoluble in organic solvents like ether.
Erythrosine has strong light absorption properties, particularly in the visible region, which gives it its vivid coloration.

Chemically, erythrosine is stable under normal conditions but may degrade when exposed to excessive light or heat.
Erythrosine contains multiple iodine atoms, making it relatively dense and contributing to its high molecular weight.
Erythrosine is typically used as its disodium salt form, which enhances water solubility.

Erythrosine has a melting point that is not sharply defined due to decomposition upon heating.
Erythrosine's pH in aqueous solution is typically neutral to slightly acidic.
Erythrosine also exhibits fluorescence, which is useful in analytical and diagnostic applications.

CHARACTERISTICS of ERYTHROSINE:
Erythrosine is notable for its intense color strength and stability in aqueous environments.
Erythrosine binds well to proteins and surfaces, making it useful for staining and coating applications.
Its iodine content also makes Erythrosine detectable in certain analytical techniques.
Another important characteristic is Erythrosine's sensitivity to light, which can lead to fading or degradation over time if not properly stored.
Erythrosine is often stabilized with appropriate packaging and storage conditions.

BENEFITS of ERYTHROSINE:
The main benefit of erythrosine is its strong coloring ability at low concentrations, making it cost-effective and efficient.
Erythrosine provides consistent and reproducible coloration, which is important in industrial applications.
Erythrosine's water solubility allows for easy incorporation into aqueous systems, and its compatibility with various formulations makes it versatile across industries.

PRODUCTION METHOD of ERYTHROSINE:
crude fluorescein obtained by heating and melting resorcinol, phthalic anhydride and anhydrous zinc chloride is refined and iodized, salted out with sodium chloride, and then refined.
Preparation of erythrosine Resorcinol is heated and melted, added with phthalic anhydride, stirred and melted, heated to 185 ℃ for half an hour to form dark yellow resorcinolphthalide, which is in a liquid state.
Add powdered anhydrous zinc chloride under stirring, stir until it is completely dissolved, and gradually raise the temperature to 210~215 ℃, heat until the reactants are completely solidified, then cool and pulverize to obtain a crude melt.

The crude melt is heated with dilute hydrochloric acid In azeotrope, zinc chloride and residual resorcinol are leached, filtered, washed, and dried, and then ethanol is used to extract unreacted phenorcinolphthalide, and the extracted product is dried to obtain fluorescein.
Dissolve fluorescein in sodium hydroxide solution, add iodine to react, add hydrochloric acid to the reactants, precipitate crystals, and then convert it into sodium salt solution, and concentrate to obtain the product.

Preparation of erythrosine red aluminum lake Aluminum hydroxide is prepared from aluminum salts such as aluminum chloride, aluminum sulfate, etc. and bases such as sodium carbonate, and then added to erythrosine aqueous solution to precipitate the product.
Erythrosine formed by the condensation of benzaldehyde -4-sulfonic acid and diethylm-aminophenol is dehydrated by concentrated sulfuric acid and oxidized with potassium dichromate, permanganate or ferric chloride to make sodium salt.

WHICH FOODS CONTAIN ERYTHROSINE?
The watermelon red or the cherry red erythrosine is used in a variety of food products, including candied cherries, cocktail cherries, bigarreaux cherries in syrup, cocktails, and popsicles, cake decorating gels, sports drinks, cream biscuits, gems, candies, and other condiments.
Apart from foods and beverages, certain medications, such as ibuprofen, are coated with erythrosine.
The red colour dye in the tablets is a source of iodine in the diet.

PRODUCTION of ERYTHROSINE:
Erythrosine is synthesized from resorcinol and phthalic anhydride, which are processed into fluorescein.
Fluorescein then undergoes iodination, producing the bright red dye.

PREPARATION METHOD of ERYTHROSINE:
Dissolve fluorescein with sodium hydroxide solution to prepare fluorescein disodium salt, and then add 4 equivalents of iodine to it for iodine Subgeneration reaction to obtain erythrosine B.
The operation of this synthetic route is relatively simple, and the current industrial preparation of tetraiodofluorescein B basically adopts this route.

HISTORY of ERYTHROSINE:
Erythrosine was discovered by the Swiss chemist Karl Kussmaul at the University of Basel in 1876 and soon commercialized by the local Bindschedler & Busch company for dyeing wool and silk.
Erythrosine's use as a textile dye was soon superseded due to its propensity to fade in sunlight.
Erythrosine's use as a food dye was legalized in the US by the Pure Food and Drug Act of 1906.
By early 1920s, Erythrosine was produced mainly for the food industry, with 2,170 pounds (0.98 t) made in America in 1924, rising to 9,468 pounds (4.29 t) in 1938 and approximately 50 tons in 1967.

WHERE DO YOU FIND ERYTHROSINE?
Erythrosine has been widely used in a range of consumer goods to enhance their visual appeal.
Some common applications include:
Food:
Candies, baked goods, maraschino cherries, glacé fruits, and certain processed snacks often contain Erythrosine to achieve their vibrant red colour.

Beverages:
Soft drinks, flavoured syrups, and powdered drink mixes are frequently dyed with Erythrosine to make them more visually enticing.

Medicines:
Liquid medications and chewable tablets often use synthetic dyes like Erythrosine for colour-coding and branding purposes.

Cosmetics:
Products such as lipsticks, blushes, and nail polishes have traditionally relied on Erythrosine for its long-lasting and vivid pigment.

Other Products:
Erythrosine can also be found in pet foods and decorative items like cake icings, where aesthetics play a significant role.

PHYSICAL AND CHEMICAL PROPERTIES of ERYTHROSINE:
Erythrosine is a hard and brittle white high melting point wax.
At or above the melting point, soluble in mixed xylene, terpenes, butanol, methyl cellosolve and other high boiling point solvents and hot chlorinated hydrocarbons and aromatic solvents, but insoluble in water, ethanol, benzene, carbon tetrachloride, glycerol and other solvents.

PHYSICAL and CHEMICAL PROPERTIES of ERYTHROSINE:
CAS: 16423-68-0
EINECS: 240-474-8
InChI: InChI=1/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
InChIKey: RAGZEDHHTPQLAI-UHFFFAOYSA-L
Molecular Formula: C20H6I4Na2O5
Molar Mass: 879.86
Density: 0.98
Melting Point: 142~144℃
Boling Point: 628.3°C at 760 mmHg
Flash Point: 285℃

Water Solubility: Soluble in water
Solubility: 100g/l
Vapor Presure: 0Pa at 25℃
Appearance: Fine Powder
Color: Deep red to brown
Maximum wavelength(λmax): ['525nm']
Merck: 14,3693
BRN: 1443945

pKa: 4.1(at 25℃)
PH: 6-7 (10g/l, H2O, 20℃)
Storage Condition: room temp
Stability: Stable. Incompatible with strong oxidizing agents.
Molecular Formula / Molecular Weight: C20H6I4Na2O5 = 879.86
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Hygroscopic

CAS RN: 16423-68-0
Reaxys Registry Number: 3583865
PubChem Substance ID: 87576473
Merck Index (14): 3693
Colour Index: 45430
MDL Number: MFCD00144257
Chemical formula: C20H6I4Na2O5
Molar mass: 879.86 g/mol
Melting point: 142 to 144 °C (288 to 291 °F; 415 to 417 K)

Empirical Formula (Hill Notation): C20H6I4Na2O5
CAS Number: 16423-68-0
Molecular Weight: 879.86
UNSPSC Code: 41116130
NACRES: NA.21
MDL number: MFCD00144257
Physical state: solid
Form: powder
Color: red brown

Odor: No data available
Melting point/range: 315 °C (978,5 hPa)
Method: OECD Test Guideline 102
Boiling point: No data available
Flammability: No data available
Upper explosion limit / Upper flammability limit: No data available
Lower explosion limit / Lower flammability limit: No data available
Flash point: 182 °C (977,7 hPa)
Method: ISO 2719, closed cup

Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 6,4 (30,3 °C)
Viscosity, dynamic: No data available
Viscosity, kinematic: No data available
Flow time: No data available
Solubility(ies) Water solubility: 79,787 g/l (30 °C)
Partition coefficient: n-octanol/water: log Pow: -1,163 (25 °C)

Method: OECD Test Guideline 107
Bioaccumulation is not expected.
Vapor pressure: No data available
Relative density: No data available
Density: 0,625 - 0,731 g/cm3 (30,1 °C)
Method: OECD Test Guideline 109
Relative vapour density: No data available
Explosives: Not classified as explosive.
Oxidizing properties: none

Burning rate: No data available
Evaporation rate: No data available
Molecular weight: 879,87 g/mol
Molecular Weight: 835.9 g/mol
XLogP3-AA: 6
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 0
Exact Mass: 835.6551 Da
Monoisotopic Mass: 835.6551 Da

Topological Polar Surface Area: 76 Å²
Heavy Atom Count: 29
Formal Charge: 0
Complexity: 645
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

FIRST AID MEASURES of ERYTHROSINE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of ERYTHROSINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of ERYTHROSINE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ERYTHROSINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ERYTHROSINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of ERYTHROSINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available