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Delta-Gluconolactone (GDL) is a lactone of the D-gluconate.
Delta-Gluconolactone (GDL) is a natural constituent of many foods.
Delta-Gluconolactone (GDL) can be found in honey, fruit juices, wine and many-fermented products1-3.
CAS No.:90-80-2.
Chemical Name:Glucono-Delta-Lactone(Gdl)
CBNumber:CB31027445
Molecular Weight:178.14
MOL File:90-80-2.mol
Molecular Formula:C6H10O6
Synonyms: GLUCONOLACTONE, GLUCONO-DELTA-LACTONE, GDL, D-GLUCONO-1,5-LACTONE, (3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-one, DELTA-GLUCONOLACTONE, Glucosactone, Glucono-δ-Lactone, Glucono, Glucolactone
Gluconolactone is a non-toxic component of the skin.
It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties.
It acts as aβ-glucosidase inhibitor.
Gluconolactone stimulates cellulase gene expression.
Delta-Gluconolactone (GDL) is used as a food additive with the E number E575 used as a sequestrant, an acidifier (Delta-Gluconolactone (GDL) lower the pH and also help preserve the food from deterioration by enzymes and organisms), or a curing, pickling, or leavening agent.
GDL has been marketed for use in feta cheese.
GDL is neutral, but hydrolyses in water to gluconic acid that is acidic, adding a tangy taste to foods, though Delta-Gluconolactone (GDL) has roughly a third of the sourness of citric acid.
Delta-Gluconolactone (GDL) can be used as nutritional supplement in beverage such as in Instant Drinks, Syrups, RTD Tea and Coffee, Sports and Energy Drinks, Waters.
Glucono delta-lactone (C6H10O6), molecular weight 178.14, is an inner ester of gluconic acid.
Commonly named gluconolactone, other synonyms include D-gluconic acid delta-lactone, D-glucono- 1, 5-lactone, and D-delta-gluconolactone.
Some of its earliest uses as a food ingredient were as a flavoring (e.g., sherbets) and to reduce fat absorption in doughnuts and cones.
Glucono deltalactone tastes sweet initially and has a slightly acid-aftertaste.
Physicochemical properties
Appearance : White crystals or crystalline powder, odorless, with a sweet taste followed by a sour taste.
Melting point : 153℃.
Solubility : Easily soluble in water, with solubility in water increasing with increasing temperature; slightly soluble in ethanol; insoluble in ether.
Stability : Stable under dry conditions, but slowly hydrolyzes in aqueous solution to form gluconic acid.
Heating accelerates the hydrolysis reaction.
Properties Melting point: 160 °C (dec.)(lit.)
Alpha: 65 º (c=1,H2O)
Boiling point: 230.35°C (rough estimate)
Density: 0.6
Bulk density: 750 kg/m3
Refractive index: 63.5 ° (C=10, H2O)
Storage temperature: Sealed in dry, room temperature
Solubility: 590 g/L (hydrolysis)
Form: Crystalline powder
pKa: 12.06±0.60 (Predicted)
Color: White to off-white
Odor: White crystalline powder, practically odorless
pH: 3.6 (10 g/L, H2O, 20°C)
Biological source: Microbial
Water solubility: 500 g/L (20°C)
Merck: 14,4457
BRN: 83286
Major application: Pharmaceutical (small molecule)
Cosmetic ingredient functions: Skin conditioning
InChI: 1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1
InChIKey: PHOQVHQSTUBQQK-SQOUGZDYSA-N
Preparation
Glucono delta-lactone is prepared commercially by the oxidation of glucose with bromine water.
Definition
Glucono-Delta-Lactone(Gdl) has a role as an animal metabolite and a mouse metabolite.
Glucono-Delta-Lactone(Gdl) is a gluconolactone and an aldono-1,5-lactone.
Glucono-Delta-Lactone(Gdl) is functionally related to a D-gluconic acid.
Production methods
Glucose is typically used as a raw material, and under the action of a catalyst, Glucono-Delta-Lactone is oxidized by air or oxygen to produce gluconic acid.
Then, gluconic acid is lactone-formed under certain conditions to obtain gluconolactone.
Commonly used catalysts include sodium bromide and sodium nitrite.
Uses
Geogard(R)Ultra is a synergistic blend of gluconolactone and sodium benzoate.
This blend provides broad spectrum protection against product spoilage in a variety of personal care formulations.
Product Data Sheet
A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.
a product of the oxidation of glucose by glucose oxidase
gluconolactone is used in cosmetics for its anti-acne properties.
Delta-Gluconolactone (GDL) can also help improve skin hydration given its water-binding ability.
In addition, formulators may select gluconolactone for its action as a product stabilizer (chelating agent).
Some studies indicate potential free-radical scavenging capacities as well.
These properties would make it particularly relevant for use in making anti-aging, moisturizing, and possibly sun care products.
(GDL) An acidulant.
Delta-Gluconolactone (GDL) hydrolyzes to form gluconic acid in water solution and thereby creates the desired pH.
The rate of acid formation is affected by temperature, concentration, and the pH of the solution.
Delta-Gluconolactone (GDL) has low acid release at room temperature and accelerated conversion into gluconic acid at high temperatures.
Delta-Gluconolactone (GDL) is readily soluble with a solubility of 59 g in 100 ml of water at 20°C.
Delta-Gluconolactone (GDL) functions as a leavening agent, acidulant, curing and pickling agent, and pH control agent.
Delta-Gluconolactone (GDL) is comparatively less tart/sour than other food acids.
Delta-Gluconolactone (GDL) is used in baked goods, fish products, desserts, and dressings.
D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to achieve a curing, pickling or leavening effect.
Component of many cleaning cmpds because of the sequestering ability of the gluconate radical which remains active in alk solutions; in the dairy industry to prevent milkstone; in breweries to prevent beerstone; as latent acid catalyst for acid colloid resins, particularly in textile printing; as a coagulant for tofu.
Use
Food Industry : Glucono-Delta-Lactone is a multifunctional food additive.
As a coagulant, Glucono-Delta-Lactone is used in the production of tofu, making the tofu delicate, smooth and delicious, and with a high yield; as an acidulant, Glucono-Delta-Lactone can be used in fruit juices, fruit wines, etc., to adjust the pH value of the products and improve the flavor; Glucono-Delta-Lactone can also be used as a preservative to extend the shelf life of food, playing a role in pickled products, preserved vegetables, etc.
In the pharmaceutical field : Glucono-Delta-Lactone can be used as a pharmaceutical intermediate in the synthesis of various drugs.
Simultaneously, Glucono-Delta-Lactone also possesses certain detoxification and hepatoprotective properties, capable of binding with toxic substances entering the body to form non-toxic compounds that are excreted. Glucono-Delta-Lactone is commonly used to treat acute and chronic hepatitis, cirrhosis, and other diseases.
In the cosmetics industry : when added to cosmetics, Glucono-Delta-Lactone can act as a pH adjuster and moisturizer, helping to maintain the skin's acid-base balance, retain skin moisture, and make the skin soft and smooth.
Other applications : In the textile industry, Glucono-Delta-Lactone can be used as a fiber treatment agent to improve fiber performance; in the electroplating industry, Glucono-Delta-Lactone can be used as an additive to enhance electroplating results.
Security
Gluconolactone is a safe food additive widely used in the food industry. When used within the scope and limits stipulated by national standards, Glucono-Delta-Lactone is harmless to human health. The oral LD50 in rats is 7630 mg/kg, classifying it as a low-toxicity substance.
Packaging and Storage
Generally packaged in woven plastic bags or cardboard drums lined with food-grade plastic bags, each bag (drum) weighs 25kg net, or packaged according to customer requirements.
