GLUCITOL

Glucitol, also known as Sorbitol, is a sugar alcohol derived from glucose and widely used as a low-calorie sweetener, humectant, and stabilizer in food, pharmaceutical, cosmetic, and industrial applications.
Glucitol occurs naturally in many fruits and is produced commercially by the hydrogenation of glucose.
Glucitol is valued for its non-cariogenic properties, low glycemic index, and moisturizing capabilities.

CAS Number: 50-70-4
EC Number: 200-061-5
Molecular Formula: C6H14O6
Molecular Weight: 182.17 g/mol

Synonyms: Sorbitol, D-Sorbitol, D-Glucitol, Sorbo, Sorbitol Solution, Sorbitol Powder, Sorbitol Syrup, Hydrogenated Glucose, Hexanehexol, Glucitol Sweetener, Glucitol, D‑Glucitol, L‑Glucitol, Sorbitol, D‑Sorbitol, L‑Sorbitol, Hexane‑1,2,3,4,5,6‑hexol, Sugar alcohol, Polyhydric alcohol, Hexitol, D‑Hexitol, Glucose alditol, Polyol C6H14O6, Sorbogem, Sorbo, Neosorb, D‑Glucit, D‑Sorbit, D‑Hexanhexol, α‑Glucitol, β‑Glucitol, D‑Glucitol (GMP grade), L‑Glucitol (Pharma grade), Food‑grade glucitol, Technical‑grade glucitol, Crystal sorbitol, Syrup sorbitol, Liquid sorbitol, Sorbitol syrup, Sorbitol 70 % soln, Sorbitol 99 % USP, Sorbitol powder, Sorbitol crystals, E 420, USP sorbitol, BP sorbitol, PhEur sorbitol, FCC sorbitol, Grade‑A sorbitol, Neosorb 70, Multitol, Dulcitol (typo), Sweenol, Glucour, Glucoket, Glucitor, Sorbitol‑6‑phosphate, Mannitol isomer, Mannitol analog, Reduction product of glucose, Hydrogenated sugar, Polyol sweetener, Low‑calorie sweetener, Dental‑friendly sweetener, Bulking agent, Humectant‑grade sorbitol, Emollient‑grade glucitol, Pharmaceutical sorbitol, Laxative‑grade sorbitol, Cathartic sorbitol, Diuretic sorbitol, Sorbitol USP solution, Sorbitol buffer, Osmotic laxative, Cosmetic humectant, Oral care sorbitol, Tablet diluent, Plasticizer sorbitol, Stabilizer sorbitol, Alkyd plasticizer glucitol, Vinyl resin stabilizer, Rigid foam additive, Cryo‑protectant sorbitol, Polyol feedstock, Ascorbic acid precursor sorbitol, Propylene glycol feedstock, Research reagent sorbitol, 

APPLICATIONS

Glucitol is widely used in sugar-free and reduced-calorie food products as a sweetener.
Glucitol is added to sugar-free candies, chewing gums, and baked goods to provide sweetness without raising blood sugar levels.
Glucitol contributes to texture, moisture retention, and shelf-life extension in food items.

Glucitol is included in pharmaceutical formulations as a sweetening agent and excipient.
Glucitol is used in syrups, lozenges, chewable tablets, and vitamin formulations.
Glucitol acts as a plasticizer and stabilizer in drug delivery systems.

Glucitol is used in oral care products, such as toothpaste and mouthwash, for its non-cariogenic and humectant properties.
Glucitol helps retain moisture and prevents drying in gels and pastes.
Glucitol reduces plaque formation and supports oral hygiene.

Glucitol is incorporated into cosmetics and personal care products as a humectant and skin-conditioning agent.
Glucitol is found in moisturizers, shampoos, creams, and lotions to improve hydration and texture.
Glucitol provides a smooth feel and enhances the sensory profile of formulations.

Glucitol is employed in industrial fermentation as a carbon source for microbial cultures.
Glucitol supports the growth of certain bacteria and yeast in biotechnology applications.
Glucitol is used in research for osmotic stress studies and biochemical assays.

Glucitol is used in the production of polyurethane foams and resins.
Glucitol improves plasticity, stability, and moisture resistance in polymers.
Glucitol is added to adhesives and sealants for improved flexibility.

Glucitol is applied in agricultural formulations as a carrier for active ingredients.
Glucitol enhances solubility and stability of foliar sprays and crop treatments.
Glucitol supports plant hydration and nutrient transport.

Glucitol is utilized in dietary fiber and prebiotic formulations to promote gut health.
Glucitol ferments slowly in the colon, contributing to mild laxative effects and microbiome balance.
Glucitol is used in combination with other polyols in digestive wellness products.

Glucitol is used in medical nutrition products for patients with diabetes or metabolic disorders.
Glucitol is included in enteral nutrition and meal replacement shakes as a carbohydrate alternative.
Glucitol provides energy with minimal glycemic impact.

Glucitol is added to tobacco and e-cigarette products as a humectant and flavor enhancer.
Glucitol retains moisture in tobacco leaves and vaping liquids.
Glucitol improves the smoothness and consistency of the product.

Glucitol is used as a sugar substitute in sugar-free chewing gums.
Glucitol is included in diabetic-friendly candies to provide sweetness without raising blood sugar.
Glucitol is used in oral care products like toothpaste and mouthwash to prevent tooth decay.
Glucitol is applied in pharmaceutical syrups as a non-cariogenic sweetening agent.

Glucitol is incorporated into sugar-free lozenges and cough drops.
Glucitol is used in liquid medications to improve palatability.

Glucitol is added to baked goods for diabetic diets.
Glucitol is used in the formulation of sugar-free chocolates and confectionery.

Glucitol is used in protein bars as a low-glycemic index sweetener.
Glucitol is applied in functional beverages targeting weight-conscious consumers.
Glucitol is used in gelatin-based desserts for calorie reduction.

Glucitol is added to processed meats to retain moisture and texture.
Glucitol is included in the production of soft drinks with low calorie content.

Glucitol is used in dietary supplements to enhance taste.
Glucitol is used in laxative formulations due to its osmotic properties.
Glucitol is included in enteral nutrition formulas for patients with special dietary needs.

Glucitol is used in cosmetics as a humectant to retain skin moisture.
Glucitol is added to lotions and creams to improve skin hydration.

Glucitol is incorporated into facial masks for moisturizing effects.
Glucitol is used in makeup products to maintain texture and moisture.

Glucitol is used in hair care products to prevent dryness and frizz.
Glucitol is added to sunscreens to provide moisture without greasiness.
Glucitol is used in aftershave balms to soothe skin.

Glucitol is used in oral rehydration solutions.
Glucitol is used in chewable tablets for improved mouthfeel.

Glucitol is used in liquid nutritional supplements.
Glucitol is used in syrups for pediatric medicines.
Glucitol is incorporated into shaving creams for enhanced glide and hydration.

Glucitol is used in wound care products to maintain a moist environment.
Glucitol is used in deodorants to balance moisture levels.

Glucitol is added to bath products like gels and bombs for skin-softening effects.
Glucitol is used in pet foods for moisture retention.

Glucitol is used in veterinary medicines as a sweetener.
Glucitol is used in biotechnological fermentation processes as a carbon source.

Glucitol is used in oral sprays for throat soothing effects.
Glucitol is used in effervescent tablets for balanced taste and solubility.
Glucitol is added to energy drinks for sustained release of sweetness.

Glucitol is used in herbal cough syrups for taste masking.
Glucitol is used in freeze-dried fruit products to enhance texture.

Glucitol is used in baby formulas to mimic lactose functionality.
Glucitol is used in toothpaste for children to provide a sweet, safe flavor.
Glucitol is used in color cosmetics to prevent cracking or caking.

Glucitol is used in bakery glazes to retain gloss and softness.
Glucitol is added to chewing gum bases to improve chewiness.

Glucitol is used in snack coatings for a non-sticky, pleasant mouthfeel.
Glucitol is used in cold creams to maintain emollient properties.

Glucitol is added to topical gels to deliver active ingredients smoothly.
Glucitol is used in tablet coatings to improve swallowing ease.

Glucitol is used in syrups for oral vaccines to enhance palatability.
Glucitol is used in slow-release capsules for sustained sweetening effect.

DESCRIPTION

Glucitol is a white, crystalline powder or a clear, colorless syrup depending on its physical form.
Glucitol has a mild sweetness approximately 60% that of sucrose.
Glucitol is odorless and non-volatile under normal conditions.

Glucitol is derived from the catalytic hydrogenation of glucose.
Glucitol occurs naturally in apples, pears, plums, and other stone fruits.
Glucitol is stable under heat and acidic conditions, making it suitable for various formulations.

Glucitol has a low glycemic index and is poorly absorbed in the small intestine.
Glucitol provides fewer calories than sugar—approximately 2.6 kcal/g.
Glucitol is non-cariogenic and does not contribute to tooth decay.

Glucitol has hygroscopic properties and is effective in moisture retention.
Glucitol’s cooling effect when dissolved in the mouth enhances its use in confections.
Glucitol may cause gastrointestinal discomfort in large quantities due to fermentation in the colon.

Glucitol is considered safe by food and drug authorities worldwide and is approved for use in foods, cosmetics, and pharmaceuticals.
Glucitol is generally recognized as safe (GRAS) by the U.S. FDA and permitted in the EU as E420.
Glucitol may be labeled as a polyol or sugar alcohol on nutritional panels.
Glucitol, also known as sorbitol, is a sugar alcohol derived from glucose.

Glucitol is commonly used as a low-calorie sweetener in food and pharmaceutical applications.
Glucitol has a low glycemic index, making it suitable for diabetic diets.
Glucitol exhibits humectant properties, helping retain moisture in products.

Glucitol is non-cariogenic and does not contribute to tooth decay.
Glucitol is a white, crystalline powder or clear viscous liquid depending on form.

Glucitol is slowly absorbed in the human intestine, reducing its impact on blood sugar.
Glucitol is classified as GRAS (Generally Recognized As Safe) by regulatory authorities.

Glucitol may have a mild laxative effect when consumed in excess.
Glucitol is used across a wide range of industries including food, cosmetics, and pharmaceuticals.

PROPERTIES

Chemical Name: D-Glucitol
Molecular Formula: C6H14O6
Molecular Weight: 182.17 g/mol
Appearance: White crystalline powder or clear colorless viscous liquid
Odor: Odorless
Taste: Mildly sweet, cooling effect
Solubility: Highly soluble in water and glycerol
Melting Point: 95–100°C (anhydrous)
Boiling Point: Decomposes before boiling
Density: ~1.29 g/cm³ (syrup)
pH (50% solution): 5.0–7.0
Stability: Stable under normal storage; hygroscopic
Storage: Store in sealed containers in a cool, dry place
Shelf Life: Up to 24 months
Regulatory Status: GRAS (FDA), E420 (EU); allowed in food, pharma, cosmetics

FIRST AID

Inhalation:
Not likely hazardous in solid or syrup form.
Move to fresh air if dust or vapor causes discomfort.
Seek medical attention if symptoms persist.

Skin Contact:
Rinse with water.
No significant irritation expected.
Use protective gloves if handling large quantities.

Eye Contact:
Rinse thoroughly with water for at least 15 minutes.
Remove contact lenses if applicable.
Seek medical attention if irritation continues.

Ingestion:
Non-toxic in moderate amounts.
May cause bloating or diarrhea if consumed in excess.
Provide water and monitor symptoms; seek medical help if needed.

Note to Physicians:
Symptomatic treatment only.
Large ingestion may lead to osmotic diarrhea.

HANDLING AND STORAGE

Handling:
Use standard hygiene precautions.
Avoid creating dust when handling powder form.
Wash hands after use.

Ventilation:
Use in well-ventilated areas.
No special ventilation required under normal conditions.

Storage:
Keep containers tightly sealed to prevent moisture uptake.
Store in a cool, dry, clean environment away from incompatible substances.
Protect from excessive heat and direct sunlight.

Spill Procedures:
Wipe or scoop up spills and rinse with water.
Avoid slipping hazard on wet floors.

Disposal:
Dispose in accordance with local environmental regulations.
May be safely flushed with water in small quantities.