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Glycerol monopalmitate is a monoacylglycerol that contains palmitic acid at the sn-1 position.
Glycerol monopalmitate is an emulsifying agent and has been used to increase the viscoelasticity of processed cheese.
Glycerol monopalmitate is a 1-monoglyceride that has palmitoyl as the acyl group.
CAS: 542-44-9
MF: C19H38O4
MW: 330.5
EINECS: 208-812-9
Synonyms
(±)-hexadecanoicacid2,3-dihydroxypropylester;1,2,3-Propanetriol 1-hexandecanoyl ester;1-Monopalmitoylglycerol;1-Palmitoylglycerol;2,3-Dihydroxypropyl palmitate;Glycerinfattyacidester;Glycerol 1-monopalmitate;Glycerol 1-palmitate
A natural product found in Neolitsea daibuensis.
Glycerol monopalmitate has a role as a plant metabolite and an algal metabolite.
Glycerol monopalmitate is functionally related to a hexadecanoic acid.
Glycerol monopalmitate is a fatty acid that contains nitrogen atoms.
Glycerol monopalmitate has hypoglycemic effects and is used to treat metabolic disorders.
Glycerol monopalmitate has been shown to have a protective effect on the liver by decreasing the levels of triglycerides in the blood and preventing lipid peroxidation.
Glycerol monopalmitate also improves glucose metabolism and insulin sensitivity.
Glycerol monopalmitate is an important component of biological membranes, where it forms a hydrophobic region that helps maintain membrane structure.
Glycerol monopalmitate also has hemolytic activity, which may be due to its ability to bind with phospholipids or cell membranes, leading to changes in their permeability or stability.
The stability of Glycerol monopalmitate can be tested by adding reagents such as sodium nitrite or potassium permanganate, which will cause a color change from yellow to brown if it reacts
Glycerol monopalmitate, also known as glyceryl monopalmitate, is a glyceride derived from palmitic acid and glycerol.
Glycerol monopalmitate is a white to off-white solid at room temperature and is classified as a monoacylglycerol.
Glycerol monopalmitate is characterized by its hydrophobic tail, which consists of a long-chain fatty acid (palmitic acid), and a hydrophilic head, which is the glycerol moiety.
Glycerol monopalmitate is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water due to its fatty acid component.
Glycerol monopalmitate is commonly used in food, pharmaceutical, and cosmetic formulations as an emulsifier, stabilizer, and thickening agent.
Additionally, Glycerol monopalmitate plays a role in the digestion and absorption of dietary fats.
Glycerol monopalmitate is generally recognized as safe (GRAS) when used in food applications, but its safety and efficacy depend on the concentration and context of use.
Overall, Glycerol monopalmitate is valued for its functional properties in various industrial applications.
Glycerol monopalmitate Chemical Properties
Melting point: 75 °C
Boiling point: 451.3±25.0 °C(Predicted)
Density: 0.969±0.06 g/cm3(Predicted)
Storage temp.: -20°C
Solubility: soluble in Methanol
Form: powder to crystal
pka: 13.16±0.20(Predicted)
Color: White to Almost white
Biological source: plant
Synthetic: (organic)
BRN: 1728235
InChI: InChI=1S/C19H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h18,20-21H,2-17H2,1H3
InChIKey: QHZLMUACJMDIAE-UHFFFAOYSA-N
LogP: 6.067 (est)
EPA Substance Registry System: Glycerol monopalmitate (542-44-9)
Uses
Glycerol monopalmitate is a biomarker of metabolic responses to hepatotoxicants and carcinogens.
A biomarker of metabolic responses to hepatotoxicants and carcinogens.
Biochem/physiol Actions
Glycerol monopalmitate is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides.
Glycerol monopalmitate may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).
