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Glycerol Tristearate occurs naturally in many animal fats and some vegetable oils, particularly those that are rich in saturated fatty acids.
Glyceryl Tristearate is an odourless, white powder.
Glyceryl Tristearate is a triglyceride derived from three units of stearic acid.
CAS Number: 68334-00-9
Molecular Formula: C57H110O6
Molecular Weight: 891.48
EINECS Number: 269-804-9
Synonyms:287100-84-9, Glyceryl tri(stearate-1-13C), Glyceryl tri(octadecanoate-1-13C), 2,3-di((113C)octadecanoyloxy)propyl (113C)octadecanoate, Glyceryltri(octadecanoate-1-13c), Tristearin-carboxyls-13C3, Tristearin-13C3, starbld0016621, DTXSID50584042, CS-0368415, Propane-1,2,3-triyl tri(1-13C)octadecanoate, Glyceryl tri(stearate-1-13C), 99 atom % 13C, 98% (CP), Cottonseedoil,hydrogenated, Cottonseedoil,partiallyhydrogenated, Partiallyhydrogenatedcottonseedoil, BATH WAX, GLYCERYL TRISTEARATE, GLYCEROL TRIOCTADECANOATE, 1,2,3-TRIOCTADECANOYLGLYCEROL, 1,2,3-TRIOCTADECANOYL-RAC-GLYCEROL
Glyceryl Tristearate is functionally related to an octadecanoic acid.
Glyceryl Tristearate is obtained from animal fats created as a byproduct of processing beef.
Glyceryl Tristearate can also be found in tropical plants such as palm.
Glyceryl Tristearate can be partially purified by dry fractionation by pressing tallow or other fatty mixtures, leading to separation of the higher melting stearin-rich material from the liquid, which is typically enriched in fats derived from oleic acid
Glyceryl Tristearate, also known as Tristearin, is a naturally occurring fat that belongs to the group of triglycerides, which are compounds formed when three molecules of fatty acids are esterified with one molecule of glycerol.
Glyceryl Tristearate can be partially purified by dry fractionation by pressing tallow or other fatty mixtures, leading to separation of the higher melting stearin-rich material from the liquid, which is typically enriched in fats derived from oleic acid.
Glyceryl Tristearate can be obtained by interesterification, again exploiting its higher melting point which allows the higher melting tristearin to be removed from the equilibrated mixture.
In the case of Glyceryl Tristearate, all three fatty acids are stearic acid molecules, which are long-chain saturated fatty acids containing 18 carbon atoms each.
Glyceryl Tristearate is a waxy, solid substance that is typically white or slightly yellowish in appearance, and it is insoluble in water but soluble in organic solvents such as ethanol, chloroform, and benzene.
Stearin is a side product obtained during the extraction of cod liver oil removed during the chilling process at temperatures below −5 °C.
Glyceryl Tristearate is a natural product found in Lysiphlebia japonica, Aphis forbesi, and other organisms with data available.
Glyceryl Tristearate is a triglyceride that is glycerol in which all three hydroxy groups have been formally esterified with stearic acid.
Glyceryl Tristearate has a role as a plant metabolite and a Caenorhabditis elegans metabolite.
Glyceryl Tristearate derives from an octadecanoic acid
Glyceryl Tristearate, commonly referred to as Tristearin, is a type of triglyceride that consists of a glycerol backbone fully esterified with three molecules of stearic acid, which is a long-chain saturated fatty acid.
Because all three positions of glycerol are occupied by the same fatty acid, it is considered a simple triglyceride.
This chemical structure gives it a very stable and non-polar nature, making it resistant to oxidation and chemical breakdown compared to unsaturated fats.
Glyceryl Tristearate colorless crystals or powder; odorless; tasteless.
Insoluble in water; soluble in alcohol, chloroform, carbon disulfide.
Glyceryl Tristearate is a triglyceride that is glycerol in which all three hydroxy groups have been formally esterified with stearic acid.
Glyceryl Tristearate has a role as a plant metabolite and a Caenorhabditis elegans metabolite.
Most triglycerides are derived from at least two and more commonly three different fatty acids.
Like other triglycerides, stearin can crystallise in three polymorphs.
For stearin, these melt at 54 (α-form), 65, and 72.5 °C (β-form).
Note that stearin is also used to mean the solid component of an oil or fat that can be separated into components that melt at higher (the stearin) and lower (the olein) temperatures.
This is the usage meant in an example such as palm stearin.
Glyceryl Tristearate is obtained from animal fats created as a byproduct of processing beef.
Glyceryl Tristearate can also be found in tropical plants such as palm.
Melting point: 72-75 °C
Boiling point: 260 °C
solubility: Practically insoluble in water; soluble in hexane and in hot propan-2-ol .
Dielectric constant: 2.3（Ambient）
InChIKey: DCXXMTOCNZCJGO-UHFFFAOYSA-N
SMILES: O(C(=O)CCCCCCCCCCCCCCCCC)CC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCC
Glyceryl Tristearate had significant promotion effects on the proliferation of HUVSMCs induced by oxidized‐LDL.
Glyceryl Tristearate is a triacylglycerol commonly found in dietary fats.
Glyceryl Tristearate increases serum cholesterol levels in rats.
Glyceryl Tristearate is also used to form the lipid matrices of solid lipid nanoparticles.
Formulations containing tristearin are used in cosmetic products to condition skin and as thickening agents.
Stearin or glycerol tristearate or tristearoylglycerol or Glycerol trioctadecanoate is a triglyceride that is composed of glycerol in which all three hydroxy groups have been esterified with stearic acid (octadecanoic acid).
Glycerol tristearate finds application as hardening agent in the manufacture of candles and soap.
Glyceryl Tristearate also has a role as a plant metabolite. glycerol tristearate is a common constituent of animal and vegetable fats.
Glyceryl Tristearate is used in a variety of industries.
In the food industry, it is often applied as an emulsifier, thickener, or stabilizer, helping to improve texture and consistency in products like margarine, chocolate, and baked goods.
In the cosmetic and pharmaceutical industries, it functions as an emollient, lubricant, and delivery agent for active ingredients in creams, ointments, and capsules.
From a biochemical perspective, Glyceryl Tristearate serves as a storage form of energy in living organisms, as triglycerides are the main form of fat stored in adipose tissue.
When broken down, it releases glycerol and stearic acid, which can be metabolized to produce energy.
Glyceryl Tristearate usually appears as a white, waxy crystalline solid at room temperature due to the high melting point of stearic acid residues.
Glyceryl Tristearate is hydrophobic, meaning it does not dissolve in water, but it is soluble in organic solvents such as chloroform, ether, and hot ethanol.
Because of its stability and solid consistency, it contributes to the hardness of fats in natural oils and butters, and it plays a role in giving products like cocoa butter and shea butter their solid form at room temperature.
Tristearin occurs naturally in animal fats such as beef tallow, lard, and dairy fats, as well as in certain plant oils like cocoa butter and shea butter, which are known for their high content of saturated fatty acids.
In living organisms, it acts as a major energy reserve, being stored in adipose tissues where it can be broken down into glycerol and free fatty acids during times of energy demand.
In the food industry, Glyceryl Tristearate is used as an emulsifier, stabilizer, and thickener, which improves the texture, consistency, and shelf life of processed foods.
Glyceryl Tristearate is commonly added to products such as margarine, chocolate, confectionery coatings, baked goods, and dairy substitutes to give them smoothness and to prevent fat separation.
In the pharmaceutical and cosmetic industries, it is valued for its role as an emollient and delivery agent.
It is frequently used in creams, lotions, ointments, and capsules because it improves skin feel, provides lubrication, and helps control the release of active ingredients.
Moreover, it is included in controlled-release formulations for drugs, as its slow breakdown in the body can be harnessed for extended medication delivery.
Glyceryl Tristearate is a chemical compound from the group of simple triglycerides.
All three hydroxy groups of glycerol are esterified with stearic acid.
Glyceryl Tristearate was shown that in tristearin treated human umbilical vein smooth muscle cells (HUVSMCs), the saturated fatty acid content was increased, and the compositions of polyunsaturated fatty acid (PUFA) and monounsaturated fatty acid were decreased
significantly.
Uses:
Glyceryl Tristearate is used in the following products: washing & cleaning products, polishes and waxes and plant protection products.
Glyceryl Tristearate is used for the manufacture of: chemicals, rubber products and plastic products.
Other release to the environment of Glyceryl Tristearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use. Formulation or re-packing
Glyceryl Tristearate is used in the following products: polymers, lubricants and greases and textile treatment products and dyes.
Release to the environment of Glyceryl Tristearate can occur from industrial use: formulation of mixtures and formulation in materials.
Glyceryl Tristearate is used in the following products: washing & cleaning products, metal surface treatment products, polymers, textile treatment products and dyes, pH regulators and water treatment products and leather treatment products.
Glyceryl Tristearate is used in the following areas: building & construction work.
Glyceryl Tristearate is used for the manufacture of: chemicals, rubber products, plastic products and electrical, electronic and optical equipment.
Release to the environment of Glyceryl Tristearate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Glyceryl Tristearate is widely used in the food industry because it functions as an emulsifier, stabilizer, and texture enhancer, which means it helps different ingredients that normally separate, such as oil and water, to blend smoothly and remain stable over time.
Glyceryl Tristearate is added to chocolates, margarine, confectionery coatings, and baked goods because it prevents fat from separating out, improves the smoothness of the product, and gives foods a desirable glossy appearance.
In addition, it helps extend the shelf life of processed foods by slowing down fat crystallization and maintaining product consistency during storage.
In the cosmetics and personal care industry, Glyceryl Tristearate is highly valued as an emollient, thickener, and skin-conditioning agent, which means it helps soften and smooth the skin while also giving creams and lotions a thicker, more luxurious texture.
It is used in a wide variety of products such as moisturizers, body lotions, sunscreens, lipsticks, and hair conditioners, where it not only provides a creamy consistency but also improves the product’s spreadability on the skin.
Because it is a relatively stable and non-irritating compound, it is suitable for use in formulations for sensitive skin and baby care products.
In the pharmaceutical field, Glyceryl Tristearate is often used as an excipient in tablets and capsules, meaning it serves as an inactive ingredient that helps hold the drug together, improves stability, or controls the release of the active medicine.
Glyceryl Tristearate is especially useful in controlled-release formulations, where its slow breakdown helps medications release gradually over time, providing a longer therapeutic effect.
Additionally, it can act as a lubricant and binding agent in tablet manufacturing, ensuring smooth production and consistent dosage forms.
Beyond food and healthcare, Glyceryl Tristearate also has industrial applications, particularly as a lubricant, surfactant, and coating material.
Glyceryl Tristearate is used in plastic manufacturing to improve the flexibility and processing of plastics, in paints and coatings to improve texture and application, and in biodegradable lubricants because it is both effective and environmentally safe.
Its role as a non-toxic, biodegradable material makes it a preferred ingredient in industries seeking sustainable alternatives to synthetic chemicals.
Soap, candles, candies, adhesive pastes, metal polishes, waterproofing paper, textile sizes, leather stuffing, manufacture of stearic acid.
Glyceryl Tristearate is used as a hardening agent in the manufacture of candles and soap.
Glyceryl Tristearate is mixed with a sodium hydroxide solution in water, creating a reaction which gives glycerin and sodium stearate, the main ingredient in most soap: C3H5(C18H35O2)3 + 3 NaOH → C3H5(OH)3 + 3 C18H35OONa
Glyceryl Tristearate is also added to aluminium flakes to help in the grinding process in making dark aluminium powder.
Glyceryl Tristearate is used in the following products: washing & cleaning products, plant protection products, adhesives and sealants, lubricants and greases, polishes and waxes, fertilisers and coating products.
Other release to the environment of Glyceryl Tristearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents,
automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems
with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Other release to the environment of Glyceryl Tristearate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products,treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Glyceryl Tristearate can be found in complex articles, with no release intended: vehicles.
Glyceryl Tristearate can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).
Glyceryl Tristearate is intended to be released from scented: clothes.
Safety Profile:
From a health perspective, Glyceryl Tristearate is considered to have a low hazard profile, and it is not classified as a dangerous substance under most chemical safety regulations.
When consumed in food products, it is metabolized in the body into glycerol and stearic acid, which are natural dietary components.
However, excessive intake of triglycerides, including Glyceryl Tristearate, can contribute to obesity, cardiovascular disease, and metabolic disorders, since overconsumption of saturated fats is linked to increased calorie intake and potential long-term health risks.
In terms of direct exposure, it is generally non-irritating to the skin and eyes, though in some sensitive individuals or with prolonged contact, it may cause mild irritation or allergic reactions.
If inhaled in the form of fine dust (for example, in an industrial manufacturing setting), it could cause mild respiratory irritation, although this is rare because the compound is usually handled as a solid fat or in formulated products.
Glyceryl Tristearate is generally recognized as a safe compound because it occurs naturally in many foods and is commonly used in the food, cosmetic, and pharmaceutical industries.
Unlike many industrial chemicals, it is non-toxic, biodegradable, and biocompatible, which means it can be broken down naturally in the environment and does not accumulate in living organisms.
