PRODUCTS

GLYCERYL MONOOLEATE

Glyceryl Monooleate is a biodegradable esterication product of Glycerin and Oleic Acid.
Glyceryl Monooleate is an amber liquid to be bonded at room temperature, it can be used as water-in-oil emulsier, pigment dispersant, lubricant and dispersing agent in chemical formulations.
Glycerol monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.

CAS Number: 25496-72-4
Molecular Formula: C21H40O4
Molecular Weight: 356.54
EINECS Number: 247-038-6

Synonyms: Monoolein, 111-03-5, Glyceryl monooleate, 2,3-Dihydroxypropyl oleate, 1-Monoolein, Glycerol 1-monooleate, Glyceryl oleate, Glycerin 1-monooleate, 1-Oleoylglycerol, 1-Glyceryl oleate, 1-Oleoyl-rac-glycerol, GLYCEROL MONOOLEATE, 1-Monooleoylglycerol, 1-Monooleoyl-rac-glycerol, Glyceryl 1-oleate, Aldo MO, Aldo HMO, alpha-Monoolein, Glycerol oleate, rac-1-Monooleoylglycerol, Olein, 1-mono-, Danisco MO 90, rac-1-Monoolein, Oleic monoglyceride, .alpha.-Monoolein, Glycerine monooleate, Oleoylglycerol, Olicine, Supeol, 1-Mono(cis-9-octacenoyl)glycerol, Sinnoester ogc, Oleylmonoglyceride, Dimodan LSQK, Emalsy MO, Emalsy OL, 2,3-dihydroxypropyl (Z)-octadec-9-enoate, Adchem GMO, Edenor GMO, Emcol O, Kessco GMO, Nikkol MGO, Oleic acid monoglyceride, Glycerin monooleate, Mazol GMO, Monoglyceryl oleate, Olein, mono-, Glycerol alpha-monooleate, Monoolein (VAN), 25496-72-4, Glycolube 100, monolein, Rikemal ol 100, Aldo MO-FG, Arlacel 129, Dimodan GMO 90, Rikemal O 71D, Sunsoft O 30B, Kemester 2000, Emasol MO 50, Loxiol G 10, Emerest 2421, Alkamuls GMO 45LG, Monomuls 90018, AJAX GMO, Excel O 95F, Excel O 95N, Excel O 95R, Aldo 40, Canamex Glicepol 182, Emrite 6009, Atmer 1007, Emuldan RYLO-MG 90, FEMA No. 2526, 1-Oleylglycerol, Dur-Em 204, Dur-EM 114, Glyceryl Monooleate (VAN), Oleic acid glycerol monoester, Emery oleic acid ester 2221, rac 1-Oleoyl Glycerol, HSDB 493, mono-olein, Oleoyl glycerol, Glycerol alpha-cis-9-octadecenate, Glyceryl monooleate [NF], 1-(9Z-octadecenoyl)-rac-glycerol, GMO 8903, Oleic acid, monoester with glycerol, EINECS 247-038-6, D3AEF6S35P, OL 100, Glycerol, 1-mono (9-octa-decenoate), glyceryl mono-oleate, NSC-406285, S 1096R, 9-OCTADECENOIC ACID (Z)-, 2,3-DIHYDROXYPROPYL ESTER, Monooleoylglycerol, CHEBI:75342, 9-Octadecenoic acid (9Z)-, 2,3-dihydroxypropyl ester, Glyceryl monooleate 90, Glyceryl monooleate 90%, EINECS 203-827-7, 1,2,3-Propanetriol mono((Z)-9-octadecenoate), 9-Octadecenoic acid (Z)-, monoester with 1,2,3-propanetriol, MFCD00042735, S 1096, S 1097, rac-Glycerol 1-monooleate, NSC 406285, Glycerol .alpha.-monooleate, C4YAD5F5G6, Glyceryl cis-9-octadecenoate, 1-(9Z)-octadecenoylglycerol, DTXSID3042003, 9-Octadecenoic acid, 2,3-dihydroxypropyl ester, GLYCERYL MONOOLEATE [FHFI], mono-oleoylglycerol, Glycerol .alpha.-cis-9-octadecenate, 1-(cis-9-Octadecenoyl)-rac-glycerol, 9-Octadecenoic acid, monoester with 1,2,3-propanetriol, Peceol, MG(18:1(9Z)/0:0/0:0)[rac], 9-Octadecenoicacid(Z)-,2,3-dihydroxypropylester, oleoyl-glycerol, 9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol, 9-Octadecenoic acid (Z)-, 2,3-dihydroxypropyl ester (9CI), 1-oleoyl glycerol, Glycerol 1-oleate, 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-oleoyl-2-glycerol, 1-oleoyl monoglyceride, myverol 18-99, Rylo MG 19, UNII-C4YAD5F5G6, UNII-D3AEF6S35P, Olein, mono, Ablunol GMO, DL-a-Monoolein, dl-alpha-Monoolein, Glycerol-1-oleate, Aldo MOFG, sn-1-O-(cis-9)octadecenylglycerol, Glycerol 1monooleate, Dimodan MO 90, Witconol 2421, dl-.alpha.-Monoolein, Emuldan RYLOMG 90, Glyceryl monooleate 40, Glyceryl monooleate 60, DurEm 114, DurEm 204, Glyceryl monooleate 40%, Olein, 1-mono-(8CI), Olein, 1-mono- (8CI), SCHEMBL15603, 1-GLYCERYL MONOOLEATE, Mazol 300 K (Salt/Mix), 1-(9Z-octadecenoyl)-glycerol, CHEMBL428593, GTPL5756, 1-Oleoyl-rac-glycerol - 50%, DTXCID1022003, DTXSID3027875, GLYCERYL MONOOLEATE [FCC], 1-Oleoyl-rac-glycerol, >=99%, Glycerol, 1mono (9octadecenoate), GLYCERYL MONOOLEATE [HSDB], ENDOCINE COMPONENT MONO-OLEIN, BDBM50529937, GLYCERYL MONOOLEATE [WHO-DD], LMGL01010005, NSC406285, AKOS015966695, BS-1088, DB13171, FO63124, 925-14-4, 1,2,3Propanetriol mono((Z)9octadecenoate), DB-208961, HY-128754, CS-0102558, G0082, 2,3-Dihydroxypropyl (9Z)-9-octadecenoate #, 1-Oleoyl-rac-glycerol, technical, ~40% (TLC), 9-Octadecenoic acid (Z)-,3-dihydroxypropyl ester, cis-9-Octadecenoic acid 2,3-dihydroxypropyl ester, MG (18:1/0:0/0:0), Q27071132, 9-Octadecenenoic acid (Z)-, 2,3-dihydroxypropyl ester, 9-octadecenoic acid, 2,3-dihydroxypropyl ester, (9Z)-, CFF6FE9F-EF1B-4B03-88B1-5421DCF14582, 9Octadecenoic acid (Z), monoester with 1,2,3propanetriol, 9-Octadecenoic acid (9Z)-, 2,3-dihydroxypropyl ester (9CI), 9-Octadecenoic acid (Z)-, monoester with 1,2,3-propanetriol (9CI), DL-ALPHA-MONOOLEIN;DELTA 9 CIS MONOOLEIN;GLYCERYL CIS-9-OCTADECENOATE;GLYCEROL MONOOLEATE;GLYCEROL ALPHA-MONOOLEATE;GLYCEROL-1-MONOOLEATE;oleic acid, monoester with glycerol;9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol.

Glyceryl Monooleate takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Glyceryl Monooleate is the glycerol ester of stearic acid. It is also used as hydration powder in exercise formulas.
Glyceryl Monooleate, generally referred to as monoolein (MO), is FDA approved amphiphilic lipid that is widely used during the synthesis of cubosomes.

Glyceryl Monooleate is a waxy material, but its physical form is dependent on the content of di- and triglyceride.
Glyceryl Monooleate is a polar unsaturated monoglyceride that can self-assemble in water into bicontinuous cubic structures.
The amphiphilic chemical structure of Glyceryl Monooleate with hydrophilic polar head (hydroxyl groups) and hydrophobic chains in the tail facilitates H-bond formation with water.

Glyceryl Monooleates are classified as GRAS (generally recognized as safe) due to their biodegradability, biocompatibility, and minimal toxicity.
The biodegradability was attributed to the lipolysis of Glyceryl Monooleates in different tissues via esterase activity.
The GMO-based systems, especially bicontinuous cubic and hexagonal LC phases, were highly reported as promising drug delivery.

Thanks to their unique features, which include their minimal toxicity, prolonged release rate, and thermodynamic stability upon exposure to excess water.
Glyceryl Monooleate, also known as monoglyceride of oleic acid or monoolein, is a compound formed when glycerol (a simple sugar alcohol) reacts with oleic acid (a monounsaturated fatty acid commonly found in various oils like olive and canola oil).
Glyceryl Monooleate is a type of monoester, meaning it consists of a single fatty acid molecule bonded to a glycerol molecule.

Glyceryl Monooleate is typically found as a clear, colorless to pale yellow oil and is used widely in the food, cosmetic, and pharmaceutical industries for its emulsifying and surfactant properties.
Glyceryl Monooleate is a polar lipid with a faint fatty odor.
It is a mixture of glycerides, primarily consisting of monooleate, derived from oleic acid and other fatty acids.

Glyceryl Monooleate is characterized by its ability to swell in water, forming several phases with varying rheological properties.
It is composed mainly of monoacylglycerols, with monooleoylglycerol being the predominant form, along with varying amounts of di- and triacylglycerols.
The composition is defined by the nominal content of monoacylglycerols and is typically obtained through partial glycerolysis of vegetable oils rich in triacylglycerols of oleic acid or by the esterification of glycerol with oleic acid, which can be sourced from either vegetable or animal origins.

Glyceryl Monooleates are often amber oily liquids that may be partially solid at room temperature and are known for their characteristic odor.
An appropriate antioxidant may be added to the formulation.
Glycerol monostearate exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.

Typically these are encountered as a mixture as many of their properties are similar.
Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.
Glycerol monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.

Glyceryl Monooleate is present at very low levels in certain seed oils.
Glycerol monooleate is a polar lipid that can exist in various liquid crystalline phases in the presence of dierent amounts of water.
Glycerol monooleate is considered a permeability enhancer due to its amphiphilic property.

Glycerol monooleate lyotropic mixtures can be applied to increase skin permeability in a variety of topical and transdermal formulations.
Glycerol monooleate is an amphiphilic lipid.
Glycerol monooleate is a polar unsaturated monoglyceride that can self-assemble into cubic structures.

Glyceryl monooleate is a common emulsifying agent.
Glycerol monooleate is a well-known molecule used as an additive.
Glycerol monooleate is considered a biodegradable and biocompatible material.

Glycerol monooleate is a polar lipid capable of forming various liquid crystalline phases in the presence of dierent amounts of water.
Glyceryl Monooleate is a sweetening agent prepared by esterifying commercial oleic acid derived from edible sources or long fatty acids.
Glycerol monooleate is a mixture with varying amounts of diglycerides and triglycerides.

Glycerol monooleate is a lipophilic glycerol fatty acid ester.
Glycerol monooleate has hemolytic properties.
Glycerol monooleate is an emulsier in combination with bile salts.

Glycerol monooleate is used as an absorption enhancer
Glyceryl monooleate is an unsaturated fatty acid ester of glycerol.
Glycerol monooleate is a monoglyceride with a single double bond.

Glycerol monooleate occurs naturally as a component of oils.
Glycerol monooleate is used as an ingredient in many food products.
Glycerol monooleate is a component of normal human nutrition.

Glycerol monooleate is part of animal and vegetable oils.
Glyceryl monooleate is water soluble requiring sustained release.
Glycerol monooleate is used in the synthesis of drug release.

Glycerol monooleate is used as a softener and emulsier for water emulsions.
Glycerol monooleate is also a stabilizer for oil-in-water emulsions.
Glyceryl Monooleate Food Grade is derived from edible sources or long fatty acids.

Glycerol monooleate is a pale yellow to yellow paste.
This product is used in baked goods, soft drinks.
Glyceryl monooleate is prepared by the esterification of glycerol with fatty acids, chiefly oleic acid.

As the fatty acids are not pure substances, but rather a mixture of fatty acids, the product obtained from the esterification will contain a mixture of esters, including stearic and palmitic.
The composition and, therefore, the physical properties of glyceryl monooleate may thus vary considerably from manufacturer to manufacturer; e.g. the melting point may vary from 10–35°C.
Glyceryl Monooleate is a clear amber or pale yellow liquid.

Glyceryl Monooleate is insoluble in water, very slightly soluble in cold alcohol, and soluble in hot alcohol, in chloroform, in ether, and in petroleum ether.
Glyceryl Monooleate is also oil soluble, giving it particularly desirable properties as a food emulsion.
Like other surfactants, its properties are distinct from those of the reactants.

Glyceryl Monooleate can form a micro-emulsion in water.
Glycerine is completely soluble in water, while oleic acid is 60 insoluble in water.
The hydrophilic-lipophilic balance (HLB) ofGlyceryl Monooleate is 3.8.

Glyceryl monooleate is incompatible with strong oxidizing agents. The self-emulsifying grade is incompatible with cationic surfactants.
Glyceryl Monooleate is classied by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS).
Glyceryl Monooleate, commonly known as Glyceryl monooleate (gliseril monooleat), is a monoglyceride commonly used as an emulsier in foods.

Glyceryl monooleate takes the form of a white, odorless, and sweet-tasting aky powder that is hygroscopic.
Chemically it is the glycerol ester of stearic acid.
Glyceryl Monooleate exists as three stereoisomers, the enantiomeric pair of 1-Glyceryl monooleate (gliseril monooleat) and 2-Glyceryl monooleate (gliseril monooleat).

Typically these are encountered as a mixture as many of their properties are similar.
Glyceryl Monooleate Food Grade is a pale yellow to yellow paste prepared by esterification of oleic acid that is derived either from edible sources or from tall oil fatty acids.
This product is used as a flavoring agent in baked goods, nonalcoholic beverages, and chewing gum.

Melting point: 35-37 °C
Boiling point: 449.35°C (rough estimate)
Density: 0.96 g/cm3 (25 ºC)
refractive index: 1.4626 (589.3 nm 40℃)
FEMA: 2526 | GLYCERYL MONOOLEATE
storage temp.: −20°C
solubility: chloroform: 50 mg/mL, clear, colorless
Water Solubility: <3.57mg/L(30 ºC)
Stability: Hygroscopic
InChI: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChIKey: RZRNAYUHWVFMIP-KTKRTIGZSA-N
SMILES: O(C(=O)CCCCCCC/C=CCCCCCCCC)CC(CO)O

Glyceryl Monooleate is a clear amber or pale yellow liquid.
It is an oil soluble surfactant and is classified as a monoglyceride.
Glyceryl Monooleate is used as an antifoam in juice processing and as a lipophilic emulsifier for water-in-oil applications.

Glyceryl Monooleate is a moisturizer, emulsifier, and flavoring agent. Various forms of glycerol oleate are widely used in cosmetics and it is also used as an excipient in antibiotics and other drugs.
Glyceryl Monooleate is classified by the U.S. Food and Drug Administration (FDA) as “generally recognized as safe” (GRAS).
Glyceryl Monooleate is a polar lipid that can exist in various liquid crystalline phases in the presence of dierent amounts of water.

Glyceryl monooleate is regarded as a permeation enhancer due to its amphiphilic property. Various phases of GMO/solvent system containing sodium uorescein were prepared to compare permeability using confocal laser scanning microscopy (CLSM).
Glyceryl monooleate (gliseril monooleat), commonly known as Glyceryl monooleate (gliseril monooleat), is a monoglyceride commonly used as an emulsier in foods.
Glyceryl monooleate takes the form of a white, odorless, and sweet-tasting aky powder that is hygroscopic. Chemically it is the glycerol ester of stearic acid.

Glyceryl Monooleate exists as three stereoisomers, the enantiomeric pair of 1-Glyceryl monooleate (gliseril monooleat) and 2-Glyceryl monooleate (gliseril monooleat).
Typically these are encountered as a mixture as many of their properties are similar.
Glyceryl Monooleate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.

Glyceryl monooleate is present at very low levels in certain seed oils.
Glyceryl Monooleate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidier and control release agent in pharmaceuticals; and a resin lubricant.
Glyceryl monooleate is also used in cosmetics and hair-care products.

Glyceryl Monooleate is largely used in baking preparations to add; to the food.
Glyceryl monooleate is somewhat responsible for giving ice cream and whipped cream their smooth texture.
Glyceryl monooleate is sometimes used as an antistaling agent in bread.

Glyceryl Monooleate is an oil soluble surfactant and is classied as a monoglyceride.
Glyceryl Monooleate is used as an antifoam in juice processing and as a lipophilic emulsier for water-in-oil applications
Glyceryl Monooleate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.

Glyceryl Monooleate is a clear amber or pale yellow liquid.
Glyceryl Monooleate is an oil soluble surfactant and is classied as a monoglyceride.
Glyceryl Monooleate is used as an antifoam in juice processing and as a lipophilic emulsier for water-in-oil applications.

Glyceryl Monooleate is a moisturizer, emulsier, and avoring agent. Various forms of glycerol oleate are widely used in cosmetics and it is also used as an excipient in antibiotics and other drugs
Glyceryl Monooleate serves as an emulsifier to help mix ingredients that would typically separate, such as oil and water.
This is especially useful in products like margarine, ice cream, and salad dressings, where smooth texture and consistency are essential.

In the cosmetic industry, it is used as an ingredient in creams, lotions, and other personal care products for its ability to improve the texture and enhance the spreadability of formulations.
Glyceryl Monooleate also has some potential medicinal applications, including use in drug delivery systems where it can help drugs dissolve in the body more easily. Additionally, glyceryl monooleate is recognized for its potential as a skin-conditioning agent.

Uses Of Glyceryl Monooleate:
Glycerol Monoleate is used to synthesize water soluble drugs in need of sustained-release for drug delivery.
Glyceryl Monooleate is a polar lipid that swells in water to give several phases with different rheological properties.
It is available in both nonemulsifying (n/e) and self-emulsifying (s/e) grades, the self-emulsifying grade containing about 5% of an anionic surfactant.

The nonemulsifying grade is used in topical formulations as an emollient and as an emulsifying agent for water-in-oil emulsions.
It is also a stabilizer for oil-in-water emulsions.
The self-emulsifying grade is used as a primary emulsifier for oil-in-water systems.

Glyceryl monooleate gels in excess water, forming a highly ordered cubic phase that can be used to sustain the release of various water-soluble drugs.
It is also the basis of mucoadhesive drug delivery systems.
Glyceryl monooleate is reported to enhance transdermal and buccal penetration.

Glyceryl Monooleate is used as an antifoam in juice processing and as a lipophilic emulsier for water-in-oil applications.
Glyceryl Monooleate also serves as a moisturizer, emulsier, and avoring agent. Various forms of glycerol oleate are widely used in cosmetics.
Glyceryl Monooleate is also widely used as an excipient in antibiotics and other drugs.

Glyceryl Monooleate has been used in liquid crystal studies and research shows that in the presence of monoolein, the penetration of the drug cisplatin is doubled.
Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.
Glyceryl Monooleate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.

Glyceryl Monooleate is also used in cosmetics and hair-care products.
Glyceryl Monooleate is largely used in baking preparations to add "body" to the food.
It is somewhat responsible for giving ice cream and whipped cream their smooth texture.

Glyceryl Monooleate is sometimes used as an antistaling agent in bread.
It can also be used as an additive in plastic, where GMS works as an antistatic and antifogging agent.
This is common in food packaging.

Glyceryl monooleate has a variety of uses across several industries due to its excellent emulsifying, surfactant, and skin-conditioning properties.
In the food industry, it is primarily used as an emulsifier to stabilize mixtures of water and oil in products like margarine, spreads, ice cream, and salad dressings.
Its ability to prevent ingredients from separating helps maintain smooth texture and consistency.

In the cosmetic and personal care industries, glyceryl monooleate is included in formulations for creams, lotions, shampoos, and conditioners, where it improves product texture, enhances spreadability, and helps moisturize the skin by forming a barrier to prevent moisture loss.
Additionally, it is used in the pharmaceutical field for controlled drug delivery systems, where it helps improve the solubility and bioavailability of certain active ingredients, allowing them to be absorbed more effectively by the body.
Glyceryl monooleate is also utilized in industrial applications such as lubrication and surface modification of materials, including in the production of certain types of emulsions and coatings.

In addition to its primary uses, glyceryl monooleate serves as a critical ingredient in various applications.
In the food processing industry, it is frequently found in bakery products, dairy items, and confectionery, helping to improve the texture, consistency, and shelf life of these products.
The compound’s emulsifying properties are especially beneficial in creating stable, uniform blends of ingredients that would otherwise separate, such as in chocolate and fillings.

Within the pharmaceutical industry, glyceryl monooleate is often employed in the preparation of liposomes and nanoparticles used in drug delivery systems, particularly for poorly water-soluble drugs.
This is because glyceryl monooleate helps form lipid bilayers that encapsulate the active pharmaceutical ingredients, allowing them to be delivered more efficiently to targeted areas in the body.
Glyceryl Monooleate can also be used as a surfactant in oral or topical drug formulations, aiding in the absorption of drugs through the skin or digestive system.

In personal care, beyond moisturizers and conditioners, it is a key ingredient in formulations like sunscreens and deodorants, where it serves both as an emulsifier and a stabilizer for active ingredients.
The compound also acts as a gentle cleanser and skin conditioning agent, enhancing the overall feel and performance of the product.

Furthermore, glyceryl monooleate plays a role in the textile industry, where it is used as a softener or lubricant in fabric treatments, as well as in the manufacturing of industrial lubricants that reduce friction and wear on machinery.
Its versatility and ability to interact with both hydrophobic and hydrophilic substances make it an essential component in many multi-phase systems, contributing to improved performance and stability across various formulations.

Safety Profile Of Glyceryl Monooleate:
When heated to decomposition it emits acrid smoke and irritating fumes.
Glyceryl monooleate is used in oral and topical pharmaceutical formulations and is generally regarded as a relatively nonirritant and nontoxic excipient.
Direct contact with the skin or eyes may cause mild irritation.

In some cases, prolonged or repeated exposure could lead to dermatitis or allergic reactions, especially in individuals with sensitive skin.
Although glyceryl monooleate is not typically considered to be a respiratory hazard, inhaling large amounts of dust or mist particles during manufacturing or processing could cause irritation to the respiratory system.
Glyceryl Monooleate is important to avoid inhaling any aerosolized product.

While glyceryl monooleate is used in food and pharmaceutical products, ingesting large quantities, especially from industrial sources, may lead to gastrointestinal discomfort, nausea, or other adverse effects.
Glyceryl Monooleate should not be consumed in large amounts outside of regulated products.
Glyceryl monooleate is generally considered to have low toxicity, but like many chemical compounds, it should be handled with care to avoid potential hazards.