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L-threoascorbic acid is mainly used in specific research contexts, and its biological applications are still under exploration.
L-Threoascorbic acid is suitable for whitening creams, essences, skin creams, lotions, masks, etc.
L-Threoascorbic acid is mainly used as an antioxidant and pH regulator in cosmetics and skin care products.
CAS Number: 115-83-3
EC Number: 204-276-4
Molecular Formula: C₆H₈O₆
Molecular Weight: 176.12 g/mol
SYNONYMS:
Threo-ascorbic acid, L-ascorbic acid (Threo isomer), L-2,3-dihydroxybutanoic acid (Threo isomer), L-2,3-dihydroxybutanoate, (2S,3S)-2,3-dihydroxybutanoic acid, L-Threo-2,3-dihydroxybutanoic acid, (S,S)-Ascorbic acid, Threo-L-ascorbic acid, L-2,3-dihydroxybutanoic acid (Threo form), L-2,3-dihydroxybutanoate (Threo), L-ascorbic acid (Threo-configuration), L-Threo-ascorbate, (2S,3S)-ascorbic acid, L-Threo-L-ascorbate, D-erythro-Hex-2-enono-1,4-lactone, Systematic IUPAC name, (5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one, D-Araboascorbic acid, Erythorbate, Isoascorbic acid, D-isoascorbic acid, Erythorbic acid, D-Isoascorbic acid, Isoascorbic acid, D-Araboascorbic acid, 89-65-6, D-Erythorbic acid, Araboascorbic acid, Isovitamin C, Erycorbin, Glucosaccharonic acid, Saccharosonic acid, Neo-cebicure, Mercate 5, FEMA No. 2410, FEMA Number: 2410, 2,3-Didehydro-D-erythro-hexono-1,4-lactone, D-erythro-3-Oxohexonic acid lactone, D-erythro-3-Ketohexonic acid lactone, DTXSID6026537, (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one, 3-Keto-D-erythro-hexonic acid gamma-lactone, 311332OII1, DTXCID306537, INS NO.315, CHEBI:51438, INS-315, (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one, NSC-8117, E-315, NSC8117, (5R)-5-((1R)-1,2-DIHYDROXYETHYL)-3,4-DIHYDROXYFURAN-2(5H)-ONE, erythroascorbic acid, (2R)-2-((1R)-1,2-dihydroxyethyl)-3,4-dihydroxy-2H-furan-5-one, RefChem:137724, GlyTouCan:G12164VD, G12164VD, (5R)-5-((1R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one,D-erythro-hex-2-enono-1,4-lactone, 201-928-0, D-erythro-ascorbic acid, D-(-)-Isoascorbic acid, MFCD00005378, D-erythro-Hex-2-enonic acid, g-lactone, (R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one, D-erythro-hex-2-enonic acid gamma-lactone, D-ASCORBIC ACID, ISO, D-erythro-hex-2-enono-1,4-lactone, E315, D(-)-Isoascorbic Acid (Erythorbic Acid), Erythroascorbic acid, D-, CCRIS 6568, HSDB 584, D(-?)?-?Isoascorbic Acid (Erythorbic Acid), Erythorbic acid [NF], NSC 8117, EINECS 201-928-0, 3-Oxohexonic acid lactone, D-erythro-, BRN 0084271, Ascorbic Acid EP Impurity F, Hex-2-enonic acid gamma-lactone, D-erythro-, UNII-311332OII1, D-soascorbic acid, (5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (D-Isoascorbic Acid), (5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (D-Isoascorbic Acid), Ascorbic Acid Impurity F, Sodium Ascorbate Impurity F, d-iso-ascorbic acid, ERYTHORBATE, ISOASCORBIC-ACID, d(-)-isoascorbic acid, 1f9g, D-Erythro-hex-2-enonic acid, gamma-lactone,, EC 201-928-0, Erythorbic acid (Standard), SCHEMBL18678, ERYTHORBIC ACID [II], 5-18-05-00026 (Beilstein Handbook Reference), ERYTHORBIC ACID [FCC], ISOASCORBIC ACID [MI], ERYTHORBIC ACID [FHFI], ERYTHORBIC ACID [HSDB], CHEMBL486293, SCHEMBL3700961, ERYTHORBIC ACID [MART.], HY-N7079R, ERYTHORBIC ACID [USP-RS], MSK2311, D-(-)-Isoascorbic acid, 98%, HY-N7079, Tox21_201111, AC8021, SBB017515, (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one, AKOS015856346, D-erythro-hex-2-enoic acid ?-lactone, FI09585, CAS-89-65-6, NCGC00258663-01, D-erythro-Hex-2-enoic acid gamma-lactone, D-Isoascorbic acid, >=99%, FCC, FG, SY010444, D-erythro-Hex-2-enonic acid gamma lactone, A0520, CS-0014152, NS00079026, ASCORBIC ACID IMPURITY F [EP IMPURITY], C20364, EN300-251979, F600911, Q424531, D-Isoascorbic acid 1000 microg/mL in Acetonitrile, Z1255372411, 7179C406-7CCF-4C07-9125-AA71E28FB983, (5R)-5-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-hydrofuran-2-one, Erythorbic acid, United States Pharmacopeia (USP) Reference Standard, (5R)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (non-preferred name)
L-Threoascorbic acid is a structural isomer of ascorbic acid that differs slightly in its molecular configuration and does not play the same role in biological processes as ascorbic acid.
In short, L-Threoascorbic acid is a chemically related compound but not the same as ascorbic acid, and it does not perform the same biological functions in the body.
L-Threoascorbic Acid is a structural isomer of ascorbic acid (vitamin C).
L-Threoascorbic acid is a lesser-known structural isomer of ascorbic acid (vitamin C), which is commonly recognized for its essential role in human health.
While ascorbic acid is widely studied and used for its antioxidant properties, immune support, and role in collagen synthesis, L-threoascorbic acid is not as commonly encountered in dietary supplements or consumer products.
However, L-Threoascorbic acid holds intriguing potential due to its similar antioxidant capabilities and its distinct molecular structure.
L-threoascorbic acid is characterized by a different spatial arrangement of atoms compared to L-ascorbic acid, which may give it unique properties in certain biochemical and pharmaceutical applications.
However, much of its potential remains to be fully explored, and L-Threoascorbic acid is not yet as widely used or recognized in clinical settings.
L-Threoascorbic acid (isoascorbic acid, D-araboascorbic acid) is a stereoisomer (C5 epimer) of ascorbic acid (vitamin C).
L-Threoascorbic acid is synthesized by a reaction between methyl 2-keto-D-gluconate and sodium methoxide.
L-Threoascorbic acid can also be synthesized from sucrose or by strains of Penicillium that have been selected for this feature.
L-Threoascorbic acid is an ascorbic acid.
L-Threoascorbic acid has been reported in Hypsizygus marmoreus, Grifola frondosa, and other organisms with data available.
L-Threoascorbic acid is a stereoisomer of ascorbic acid (Vitamin C).
While ascorbic acid is allowed as a synthetic ingredient in or on processed organic products at §205.605 in the NOP regulations, the issue of stereoisomers is not addressed in the rule.
A stereoisomer is a molecule that has the same formula and sequence of bonded atoms as another, but differs in L-Threoascorbic acid's three-dimensional orientation.
For example, if your hands were molecules and your palm and digits atoms, your left hand would be a stereoisomer of your right.
L-Threoascorbic acid is an isomer (structurally related molecule) of ascorbic acid (Vitamin C).
USES and APPLICATIONS of L-THREOASCORBIC ACID:
Although L-Threoascorbic acid is not as well known or commonly used as L-ascorbic acid, it does have some distinct properties and applications, particularly in research and pharmaceutical contexts.
While L-threoascorbic acid has interesting potential in research and applications, ascorbic acid (vitamin C) remains far more widely studied and used due to its well-established health benefits.
L-threoascorbic acid is mainly used in specific research contexts, and its biological applications are still under exploration.
Although research on L-threoascorbic acid is limited compared to ascorbic acid, its chemical activity as an antioxidant and reducing agent makes it an interesting subject of study for scientists and health researchers.
In this context, L-threoascorbic acid could have applications in various fields, including cellular research, skincare, and immune health.
Despite its similarities to ascorbic acid, L-threoascorbic acid is not a mainstream compound in commercial products, and its use is primarily limited to research and experimental formulations.
As the scientific community continues to study its properties and potential benefits, L-threoascorbic acid could one day become a valuable tool in both health and cosmetic industries.
Since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods intended to be eaten fresh (such as salad bar ingredients), the use of L-Threoascorbic acid as a food preservative has increased.
L-Threoascorbic acid is also used as a preservative in cured meats and frozen vegetables.
Much like ascorbic acid, L-Threoascorbic acid increases nitrosylation of the central iron atom of muscle myoglobin, resulting in the formation of reddish-brown nitrosomyoglobin and the characteristic pink color of nitrosohemochrome or nitrosyl-heme upon cooking.
Again like ascorbic acid, L-Threoascorbic acid reduces the formation of nitrosamines.
L-Threoascorbic acid is denoted by E number E315, and is widely used as an antioxidant in processed foods.
L-Threoascorbic acid is mainly used as an antioxidant and pH regulator in cosmetics and skin care products.
Physiologically, L-Threoascorbic acid's antiscorbutic capacity is only one-twentieth that of ascorbic acid.
Still, L-Threoascorbic acid has almost the same effect as ascorbic acid in terms of lowering blood pressure, diuresis, liver glycogen generation, pigment excretion, and detoxification.
L-Threoascorbic acid prevents the formation of carcinogenic nitrosamines, improves undesirable phenomena such as discoloration, off-flavors, and turbidity, and is highly safe.
L-Threoascorbic acid is suitable for whitening creams, essences, skin creams, lotions, masks, etc.
Both ascorbic acid and L-Threoascorbic acid are commonly used as anti-oxidant preservatives in a wide variety of foods.
The use of L-Threoascorbic acid as a preservative in foods intended to be eaten raw has increased since the US FDA banned the use of sulfites for this purpose.
L-Threoascorbic acid is used as an antioxidant in food and beverages to maintain the natural color and flavor without toxic and side effects.
-Possible Applications in Agriculture and Food Industry (Limited Research):
*Food Additive:
While there is no established widespread use in the food industry, L-threoascorbic acid could theoretically be used as a food preservative or antioxidant in food formulations, given its similar antioxidant activity to ascorbic acid.
*Agriculture:
Some research could potentially investigate L-Threoascorbic acid's use in plant-based products for oxidation prevention in food storage or as a preservative.
FOOD INDUSTRY (MOST COMMON USE) of L-THREOASCORBIC ACID:
Food Industry uses of L-Threoascorbic acid:
✓ Antioxidant / Preservative
L-Threoascorbic acid prevents oxidation of food components, especially fats, colors, and flavors.
L-Threoascorbic acid helps retain color in meats, seafood, and processed fruits/vegetables.
✓ Shelf-life extension
L-Threoascorbic acid slows down spoilage caused by air exposure.
Common in canned, frozen, and dehydrated foods.
✓ Prevention of nitrosamine formation
L-Threoascorbic acid is used in cured meats (bacon, ham, sausages) to reduce formation of harmful nitrosamines during processing.
✓ Bakery products
L-Threoascorbic acid helps maintain dough strength during mixing and improves overall texture.
Beverage Industry uses of L-Threoascorbic acid:
L-Threoascorbic acid stabilizes color and flavor in fruit juices, soft drinks, and wine.
L-Threoascorbic acid prevents browning due to oxidation.
Pharmaceutical & Cosmetic Applications of L-Threoascorbic acid:
✓ Antioxidant in formulations
L-Threoascorbic acid is used to stabilize ingredients in topical products, creams, and serums.
L-Threoascorbic acid protects sensitive active ingredients from oxidation.
✓ Not used as vitamin C
L-Threoascorbic acid does not contribute to nutritional vitamin C content.
Industrial Applications of L-Threoascorbic acid:
✓ Polymer and plastic stabilization
L-Threoascorbic acid is added as an antioxidant to prevent degradation of plastics and rubber.
✓ Oxygen scavenger
L-Threoascorbic acid is used in packaging materials to reduce oxygen levels and protect sensitive products.
Metal Treatment uses of L-Threoascorbic acid:
L-Threoascorbic acid acts as a reducing agent in metal surface treatment and electroplating processes.
HEALTH EFFECTS of L-THREOASCORBIC ACID:
Clinical trials have been conducted to investigate aspects of the nutritional value of L-Threoascorbic acid.
One such trial investigated the effects of L-Threoascorbic acid on vitamin C metabolism in young women; no effect on vitamin C uptake or clearance from the body was found.
A later study found that L-Threoascorbic acid is a potent enhancer of nonheme-iron absorption, just like ascorbate.
This is thought to be due to L-Threoascorbic acid exerting the same iron-reducing and iron-chelating activity as ascorbic acid.
Neither of these reactions is mediated by an enzyme, which would confer some chiral selectivity.
L-Threoascorbic acid is twice as effective as ascorbic acid in enhancing non-heme iron absorption.
Americans are estimated to ingest 200 mg of L-Threoascorbic acid per day, making it a very important factor in understanding iron absorption.
KEY CHARACTERISTICS of L-THREOASCORBIC ACID:
*Antioxidant:
Like ascorbic acid, L-Threoascorbic acid has the ability to scavenge free radicals and reduce oxidative damage.
*Less Common than Ascorbic Acid:
L-threoascorbic acid is a less studied isomer, with more limited commercial and biological use compared to ascorbic acid.
*Research Potential:
L-Threoascorbic acid holds promise for use in pharmaceutical research, biochemical experiments, and cosmetics due to its chemical properties.
*Potential Skin Benefits:
L-Threoascorbic acid could be explored for use in anti-aging and skin repair products.
*Water-Solubility:
Like ascorbic acid, L-Threoascorbic acid is likely water-soluble, which makes it suitable for formulations in liquid products like serums or topical treatments.
SUMMARY OF BENEFITS of L-THREOASCORBIC ACID:
Antioxidant and free-radical scavenging properties.
L-Threoascorbic acid supports immune health and may help in immune support research.
Potential use in skin care products and anti-aging formulations.
Possible utility in pharmaceutical and biochemical research.
L-Threoascorbic acid may support collagen production in skin (but less proven than ascorbic acid).
KEY DIFFERENCES BETWEEN L-THREOASCORBIC ACID AND ASCORBIC ACID:
Stereochemistry:
Ascorbic acid (L-ascorbic acid) has a specific stereochemistry at the 2 and 3 positions of the carbon chain.
L-Threoascorbic acid differs in the configuration at one of these centers (particularly the 3-hydroxy group).
Biological Activity:
Ascorbic acid (L-ascorbic acid) is biologically active and is a vital nutrient.
L-Threoascorbic acid has similar antioxidant properties but is not naturally occurring in humans and is not commonly used for human health applications like vitamin C.
Functionality:
Both compounds act as reducing agents and antioxidants, but ascorbic acid has a well-established role in human health as a vitamin and essential nutrient, whereas L-threoascorbic acid is more of a synthetic or theoretical compound in the context of biology and research.
CHARACTERISTICS of L-THREOASCORBIC ACID:
Antioxidant Activity:
Antioxidant Properties:
Like ascorbic acid, L-threoascorbic acid has antioxidant capabilities, meaning it can scavenge free radicals and reduce oxidative stress.
L-Threoascorbic acid can potentially protect cells from oxidative damage caused by reactive oxygen species (ROS).
Cell Protection:
L-Threoascorbic acid may be used in research settings to prevent cellular damage during experiments, particularly where oxidation plays a role in cellular aging, degenerative diseases, or other conditions.
Pharmaceutical and Biomedical Research:
Enzyme Reactions:
L-Threoascorbic acid can be used as a substrate in enzymatic reactions in vitro, especially in studies exploring antioxidant activity or the metabolism of vitamin C-related compounds.
Drug Development:
Because of its similarity to ascorbic acid, L-threoascorbic acid could potentially be studied as part of drug development for antioxidant or anti-inflammatory therapies.
Potential Role in Skin Health and Cosmetics:
Topical Applications:
In theory, L-threoascorbic acid could be considered for use in cosmetics and skin care products due to its antioxidant properties, which help neutralize free radicals that can damage skin cells.
L-Threoascorbic acid might also help protect against UV-induced skin damage, though research on this specific application is limited.
Anti-Aging:
Like ascorbic acid, L-threoascorbic acid might contribute to collagen synthesis, although it is less well-studied in this context.
L-Threoascorbic acid could potentially help maintain skin elasticity, reduce the appearance of fine lines and wrinkles, and promote overall skin health.
Research Applications in Cell Culture:
Cellular Studies:
L-Threoascorbic acid may be used in cell culture systems or biochemical experiments that require an antioxidant or reducing agent.
L-Threoascorbic acid could protect cells in cultures from oxidative damage during experiments involving stress or inflammation.
Metabolic Studies:
L-Threoascorbic acid might be used in metabolic studies that examine vitamin C metabolism in cells and organisms.
L-Threoascorbic acid's role as a precursor or derivative of ascorbic acid could offer insight into vitamin C metabolism pathways.
Potential Nutritional Supplement:
Formulation:
Although L-threoascorbic acid is not typically used as a nutritional supplement, there is the potential for it to be formulated into dietary supplements that combine it with ascorbic acid to boost antioxidant capacity or support immune health.
Immune Support:
Like ascorbic acid, L-threoascorbic acid might contribute to immune system health, although this application is still theoretical and has not been widely researched.
Comparison to Ascorbic Acid (Vitamin C):
Less Common:
L-threoascorbic acid is not as prevalent or widely used as ascorbic acid (vitamin C) in daily health applications.
However, it might be researched for its unique properties and how it can be used in combination with other antioxidants.
Biological Activity:
While L-Threoascorbic acid might have similar antioxidant and reducing properties, its biological activity has not been as well-established as ascorbic acid, which has proven health benefits like collagen synthesis, immune support, and wound healing.
PRODUCTION of L-THREOASCORBIC ACID:
Erythorbic acid is very easily produced by fermentation, being obtainable in just one step compared to ascorbic acid's two.
A number of Penicillium naturally produce L-Threoascorbic acid from glucose.
This is the original process developed in the 1960s, but L-Threoascorbic acid has low volumetric efficiency and glucose yield compared to the modern method.
Today, the industrial process is quite similar to the Reichstein process used for ascorbic acid, only chirally flipped.
Microbial fermentation first produces a 2-keto-sugar acid, e.g. by Pseudomonas fluorescens AR4 converting glucose to 2-keto-D-gluconate.
Then chemical rearrangement produces L-Threoascorbic acid.
ECONOMICS of L-THREOASCORBIC ACID:
Like ascorbic acid, the production of L-Threoascorbic acid is concentrated in China.
Its price is less volatile than that of ascorbic acid, making L-Threoascorbic acid an attractive alternative in non-nutritive uses in times of high ascorbic acid prices.
RELATED COMPOUNDS of L-THREOASCORBIC ACID:
The structurally similar C5 sugar acid, D-erythroascorbic acid, L-Threoascorbic acid is made by baker's yeast and other fungi, acting as an antioxidant in their own cells.
L-Threoascorbic acid is made by and has some antioxidant activity in Manduca sexta.
L-Threoascorbic acid has no industrial use, however.
L-Threoascorbic acid is an isomer of ascorbic acid and has an antioxidant property superior to that of ascorbic acid.
HISTORY of L-THREOASCORBIC ACID:
L-Threoascorbic acid was first synthesized in 1933 by the German chemists Kurt Maurer and Bruno Schiedt.
Also known as Isoascoribic acid, L-Threoascorbic acid is a natural product, vegetable derived food additive produced from sucrose.
L-Threoascorbic acid is an important antioxidant in the food industry, which can keep the color, natural flavor of foods and lengthen food storage without toxic and side effects.
L-Threoascorbic acid is used in cured meat processing, frozen fruits, frozen vegetables, jams, and in the beverage industry such as beer, grape wine, soft drink, fruit juice and fruit teas.
L-Threoascorbic acid’s use has increased tremendously ever since the U.S. Food and Drug Administration banned the use of sulfites as a preservative in foods to be eaten fresh (ie: salad bar ingredients).
PHYSICAL and CHEMICAL PROPERTIES of L-THREOASCORBIC ACID:
Appearance: L-Threoascorbic acid typically appears as a white crystalline solid or powder.
Molecular Formula: C₆H₈O₆
Molecular Weight: Approximately 176.12 g/mol.
Solubility:
Water Solubility: L-Threoascorbic acid is highly soluble in water.
Solubility in Alcohol: Soluble in ethanol and methanol.
Solubility in Organic Solvents: Insoluble or sparingly soluble in most organic solvents such as ether.
Melting Point: Around 190°C (decomposes upon heating).
Density: Approximately 1.65 g/cm³.
Optical Rotation: L-Threoascorbic acid is optically active, meaning it has optical isomerism and can rotate plane-polarized light due to the presence of its asymmetric carbon atoms.
Chemical Properties:
Structure: L-Threoascorbic acid has a structure similar to ascorbic acid but differs in the configuration of its hydroxyl groups.
It is an enantiomer of D-threoascorbic acid, which is not naturally occurring.
Acidity: L-Threoascorbic acid has a weakly acidic nature due to the presence of its hydroxyl and carboxylic groups.
pKa: The pKa value is approximately 4.17, indicating its ability to donate protons and participate in acid-base reactions.
Redox Properties: Like ascorbic acid, L-Threoascorbic acid acts as a reducing agent, capable of donating electrons.
It can reduce oxidizing agents and neutralize reactive oxygen species (ROS), making it a potential antioxidant.
Stability:
L-Threoascorbic acid is sensitive to oxidation, particularly when exposed to light, air, or heat.
This sensitivity leads to the formation of dehydroascorbic acid when oxidized.
The compound may undergo degradation upon exposure to elevated temperatures, UV radiation, and in alkaline conditions, losing its activity and potency.
Reactivity: L-Threoascorbic acid reacts with oxidants, turning into dehydroascorbic acid.
It forms complexes with various metal ions, such as iron and copper, enhancing its role in iron absorption in the body.
Aldehyde Groups: The compound contains aldehyde groups, which allow it to undergo condensation reactions, particularly with amino groups.
Other Chemical Properties:
Functionality:
L-Threoascorbic acid has biological activity similar to that of L-ascorbic acid (Vitamin C) in the body, involved in collagen synthesis, immune system function, and iron absorption.
It has antioxidant properties due to its ability to donate electrons and neutralize free radicals.
Reactivity with Other Substances:
In Alkaline Solutions: L-Threoascorbic acid is more stable in slightly acidic or neutral environments and may degrade when exposed to strong bases, forming products that are less active or stable.
In Acidic Solutions: It is stable in slightly acidic conditions but decomposes when exposed to high acidity.
Degradation Products: The main degradation product is dehydroascorbic acid, which has lower antioxidant activity.
Safety and Handling:
Toxicity: L-Threoascorbic acid is generally considered non-toxic and is metabolized by the body similar to ascorbic acid.
Storage: It should be stored in a cool, dry place away from light and air to prevent oxidation and degradation.
Chemical Formula: C₆H₈O₆ (same as ascorbic acid, but different stereochemistry)
Structure: L-Threoascorbic acid is an epimer (stereoisomer) of L-ascorbic acid, meaning it has the same molecular formula but different spatial arrangement of atoms, particularly the hydroxyl groups around the chiral carbon.
Difference: The main difference lies in the configuration at specific chiral centers.
This change in configuration affects its chemical reactivity and biological activity.
L-Threoascorbic acid is not typically found in nature in significant amounts.
Chemical formula: C6H8O6
Molar mass: 176.124 g·mol−1
Density: 0.704 g/cm3
Melting point: 164 to 172 °C (327 to 342 °F; 437 to 445 K) (decomposes)
Acidity (pKa): 2.1
Molecular Weight: 176.12 g/mol
XLogP3: -1.6
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 2
Exact Mass: 176.03208797 Da
Monoisotopic Mass: 176.03208797 Da
Topological Polar Surface Area: 107 Ų
Heavy Atom Count: 12
Formal Charge: 0
Complexity: 232
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
FIRST AID MEASURES of L-THREOASCORBIC ACID:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of L-THREOASCORBIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of L-THREOASCORBIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of L-THREOASCORBIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of L-THREOASCORBIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of L-THREOASCORBIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
