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Lauric Acid (Dodecanedioic acid) is a medium-length long-chain fatty acid, or lipid, that makes up about half of the fatty acids within coconut oil.
Lauric Acid (Dodecanedioic acid)’s a powerful substance that is sometimes extracted from the coconut for use in developing monolaurin.
Lauric Acid (Dodecanedioic acid) is an antimicrobial agent that is able to fight bacteria, viruses, yeasts, and other pathogens.
CAS: 143-07-7
MF: C12H24O2
MW: 200.32
EINECS: 205-582-1
Synonyms
Emery651;Dodecanoic Acid(C12:0);Lauric acid 98%;yeuguisuan;Laurosteaic acid;Lauric acid 98-101 % (acidimetric);lauric acid, pure;LAURIC ACID, 99.5+%
Because you can’t ingest lauric acid alone (Lauric Acid (Dodecanedioic acid)’s irritating and not found alone in nature), you’re most likely to get it in the form of coconut oil or from fresh coconuts.
Lauric Acid (Dodecanedioic acid) is being studied at a breakneck pace, much of the research doesn’t pinpoint what in the oil is responsible for its reported benefits.
Because Lauric Acid (Dodecanedioic acid) contains much more than just lauric acid, it would be a stretch to credit it with all of the coconut oil benefits.
Still, a 2015 analysis suggests that many of the benefits tied to Lauric Acid (Dodecanedioic acid) are directly linked to lauric acid.
Among the benefits, they suggest lauric acid could aid weight loss and even protect against Alzheimer’s disease.
Lauric Acid (Dodecanedioic acid)'s effects on blood cholesterol levels still need to be clarified.
This research suggests that the benefits of lauric acid are due to how the body uses Lauric Acid (Dodecanedioic acid).
The majority of Lauric Acid (Dodecanedioic acid) is sent directly to the liver, where it’s converted to energy rather than stored as fat.
When compared with other saturated fats, Lauric Acid (Dodecanedioic acid) contributes the least to fat storage.
Lauric Acid (Dodecanedioic acid), also known as dodecanoic acid, is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids, is a white crystalline carboxylic acid with a faint odor of bay oil or soap.
Lauric Acid (Dodecanedioic acid) has been found at high levels in coconut oil.
Lauric Acid (Dodecanedioic acid) induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.
Lauric Acid (Dodecanedioic acid) is a straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Lauric Acid (Dodecanedioic acid) has a role as a plant metabolite, an antibacterial agent and an algal metabolite.
Lauric Acid (Dodecanedioic acid) is a straight-chain saturated fatty acid and a medium-chain fatty acid.
Lauric Acid (Dodecanedioic acid) is a conjugate acid of a dodecanoate.
Lauric Acid (Dodecanedioic acid) derives from a hydride of a dodecane.
Lauric Acid (Dodecanedioic acid), also known as dodecanoic acid, is a saturated fatty acid with a 12-carbon atom chain, widely recognized for its versatile applications in various industries.
Lauric Acid (Dodecanedioic acid) is particularly valued in the food industry for its use in the production of coconut and palm kernel oils, where it contributes to flavor and texture.
Additionally, Lauric Acid (Dodecanedioic acid) is a key ingredient in the formulation of personal care products, such as soaps and cosmetics, due to its excellent emulsifying and surfactant properties.
Lauric Acid (Dodecanedioic acid)'s antimicrobial and antifungal characteristics make it a popular choice in the formulation of natural preservatives and health supplements, enhancing product stability and efficacy.
Lauric Acid (Dodecanedioic acid) Chemical Properties
Melting point: 44-46 °C (lit.)
Boiling point: 225 °C/100 mmHg (lit.)
density: 0.883 g/mL at 25 °C (lit.)
bulk density: 490kg/m3
vapor pressure: 1 mm Hg ( 121 °C)
refractive index: 1.4304
FEMA: 2614 | LAURIC ACID
Fp: >230 °F
storage temp.: 2-8°C
solubility: 4.81mg/l
form: Crystalline Powder of Flakes
pka: pKa 4.92(H2O,t =25.0) (Uncertain)
Specific Gravity: 0.883
color: White
Odor: at 100.00 %. mild fatty coconut bay oil
Odor Type: fatty
biological source: plant
explosive limit: 0.6%(V)
Water Solubility: insoluble
λmax: 207nm(MeOH)(lit.)
JECFA Number: 111
Merck: 14,5384
BRN: 1099477
Stability: Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.
Major Application: cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
Cosmetics Ingredients Functions: SURFACTANT - CLEANSING
CLEANSING
SURFACTANT - EMULSIFYING
Cosmetic Ingredient Review (CIR): Lauric acid (143-07-7)
InChI: 1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChIKey: POULHZVOKOAJMA-UHFFFAOYSA-N
LogP: 5
Dissociation constant: 5.3 at 20℃
CAS DataBase Reference: 143-07-7(CAS DataBase Reference)
Colorless needle-like crystals.
Soluble in methanol, slightly soluble in acetone and petroleum ether.
Like many other fatty acids, lauric acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.
Lauric Acid (Dodecanedioic acid) is mainly used for the production of soaps and cosmetics.
For these purposes, Lauric Acid (Dodecanedioic acid) is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.
Physical properties
Lauric Acid (Dodecanedioic acid) occurs as a white crystalline powder with a slight odor of bay oil or a fatty odor.
Lauric Acid (Dodecanedioic acid) is a common constituent of most diets; large doses may produce gastrointestinal upset.
Uses
1. Lauric Acid (Dodecanedioic acid) Used for the preparation of alkyd resins, as well as wetting agents, detergents and pesticides
2. Used for peeling vegetables and fruits with a maximum amount of 3.0g/kg.
3. Used as defoamer; GB 2760-86 provides for the spices allowed to use; used for the preparation of other food grade additives.
4. Lauric Acid (Dodecanedioic acid) is widely used in the surfactant industry and can be, according to the classification of surfactants, divided into cationic, anionic, non-ionic and amphoteric type.
The surfactants types of Lauric Acid (Dodecanedioic acid) are listed in the attached table of this item.
Some surfactants of the derivatives of dodecanoic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide).
The Lauric Acid (Dodecanedioic acid) in these derivatives can be used as citrus preservative.
Lauric Acid (Dodecanedioic acid) also has many applications in plastic additives, food additives, spices and pharmaceutical industries.
Lauric Acid (Dodecanedioic acid) is used in Butter flavors and in certain Citrus flavor types, mainly in Lemon.
The concentration used may vasy from 2 to 40 ppm, calculated upon the finished consumer product.
Given its foaming properties, the derivatives of Lauric Acid (Dodecanedioic acid) are widely used as a base in the manufacture of soaps, detergents, and lauryl alcohol.
Lauric Acid (Dodecanedioic acid) is a common constituent of vegetable fats, especially coconut oil and laurel oil.
Lauric Acid (Dodecanedioic acid) may have a synergistic effect in a formula to help fight against mircoorganisms.
Lauric Acid (Dodecanedioic acid) is a mild irritant but not a sensitizer, and some sources cite it as comedogenic.
Lauric Acid (Dodecanedioic acid) is a fatty acid obtained from coconut oil and other veg- etable fats.
Lauric Acid (Dodecanedioic acid) is practically insoluble in water but is soluble in alco- hol, chloroform, and ether.
Lauric Acid (Dodecanedioic acid) functions as a lubricant, binder, and defoaming agent.
Like many other fatty acids, Lauric Acid (Dodecanedioic acid) is inexpensive, has a long shelf-life, is nontoxic, and is safe to handle.
Lauric Acid (Dodecanedioic acid) is used mainly for the production of soaps and cosmetics.
For these purposes, Lauric Acid (Dodecanedioic acid) is reacted with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, Lauric Acid (Dodecanedioic acid) is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.
Lauric Acid (Dodecanedioic acid) is a precursor to dilauroyl peroxide, a commercial initiator of polymerizations.
Production methods
1. Industrial production methods can be grouped into two categories:
derived from the saponification or high temperature and pressure decomposition of natural vegetable oils and fats;
separated from the synthetic fatty acid.
Japan mainly uses coconut oil and palm kernel oil as the raw materials for the preparation of lauric acid.
The natural vegetable oils used to produce dodecanoic acid include coconut oil, litsea cubeba kernel oil, palm kernel oil and mountain pepper seed oil.
Other plants oil, such as palm kernel oil, tea tree seed oil and camphor tree seed oil, can also service industry to produce dodecanoic acid.
The residual C12 distillate from the extraction of dodecanoic acid, containing a large number of Lauric Acid (Dodecanedioic acid), can be hydrogenated at atmospheric pressure, without catalyst, to convert into dodecanoic acid with a yield of more than 86%.
2. Derived from the separation and purification of coconut oil and other vegetable oil.
3. Lauric Acid (Dodecanedioic acid) naturally exists in coconut oil, litsea cubeba kernel oil, palm kernel oil and pepper kernel oil in the form of glyceride.
Lauric Acid (Dodecanedioic acid) can be derived from the hydrolysis of natural oils and fats in industry.
The coconut oil, water and catalyst are added into the autoclave and hydrolyzed to glycerol and fatty acid at 250 ℃ under the pressure of 5MPa.
The content of dodecanoic acid is 45%~80%, and can be further distilled to obtain Lauric Acid (Dodecanedioic acid).
Production Methods
Lauric Acid (Dodecanedioic acid) is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Lauric Acid (Dodecanedioic acid).
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.
