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LYSINE MONOHYDROCHLORIDE

Lysine monohydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.
Lysine monohydrochloride is an amino acid salt form of lysine, widely used as a nutritional supplement, food additive, and feed additive.
Lysine monohydrochlorides chemical formula is typically C₆H₁₄N₂O₂·HCl.

CAS Number: 657-27-2
Molecular Formula: C6H14N2O2.ClH
Molecular Weight: 182.65
EINECS Number: 211-519-9

Synonyms:L-Lysine hydrochloride, L-Lysine monohydrochloride, lysine hydrochloride, L-Lysine, monohydrochloride, L-(+)-Lysine Monohydrochloride, Lysine HCl, Lysine hcl, l-, Lysine, l-, monohydrochloride, (2S)-2,6-Diaminohexanoic acid monohydrochloride, L-lysine HCl, H-Lys-OH.HCl, (S)-2,6-Diaminohexanoic acid hydrochloride, L-Lysine monohydrocholoride, L-Lysine, hydrochloride, (2S)-2,6-Diaminohexanoic acid;hydrochloride, Lysine hydrochloride (VAN), L-Lysine hydrochloride (VAN), Lysine, monohydrochloride, L-, Lysine Hydrochloride (L-Lysine Hydrochloride), H-Lys-OH HCl, (S)-2,6-Diaminohexanoic acid monohydrochloride, L-Lysine, hydrochloride (1:1), l(+)-lysine monohydrochloride, Lysine hydrochloride [USAN:USP:JAN], L-lysine.hydrochloride, H-Lys-OH·HCl, L-Lysine-Hydrochloride, L-Lysine hydrochloride (Standard), L-Lysine hydrochloride (JP17), L-Lysine, hydrochloride (1:1), L-Lysine monohydrochloride (FCC), L-Lysine monohydrochloride, reagent grade, L-Lysine monohydrochloride, BioUltra, L-Lysine monohydrochloride, cell culture grade, monohydrochloride,l-lysin;L-Lysine HCl USP;L-Lysine HCl USP/FCC, Granular;L-Lysine HCl, Feed Grade, 98.5%;L-Lysine HCl, Powder;L-Lysine hydrochloride (feed grade);L-Lysine monohydrochloride (feed grade);L-LYSINEMONOHYDROCHLORIDE,FCC

Lysine monohydrochloride provides lysine in a stable and bioavailable form.
Lysine monohydrochloride consists of the essential amino acid lysine protonated with hydrochloric acid.
Lysine monohydrochloride contains an amino group, carboxyl group, and a basic side chain.

The hydrochloride form improves stability and solubility.
Physically, it appears as a white to off-white crystalline powder.
It is highly soluble in water.

Lysine monohydrochloride is generally odorless or has a slight characteristic smell.
Lysine monohydrochloride is an essential amino acid source, meaning it cannot be synthesized by the human body.
It must be obtained from diet or supplements.

Lysine monohydrochloride plays a key role in protein synthesis.
The compound exhibits basic amino acid behavior, due to its extra amino group in the side chain.
It can participate in acid–base interactions.

This influences its biological and chemical properties.
Lysine monohydrochloride is chemically stable under normal conditions, especially in dry form.
However, it may degrade under extreme heat or prolonged storage.

Lysine monohydrochloride is widely used in nutrition and feed applications to supplement lysine deficiency.
Lysine monohydrochloride improves protein quality in diets.
This is especially important in animal feed.

Lysine monohydrochloride is best described as a water-soluble essential amino acid salt used for nutritional supplementation and protein fortification, particularly in food and feed industries.
Lysine monohydrochloride is a white or nearly white, practically odorless, free-flowing, crys talline powder. 
It is freely soluble in water, but is almost insoluble in alcohol and in ether. 

Lysine monohydrochloride melts at about 260°C with decomposition.
Lysine monohydrochloride exhibits high hygroscopicity, meaning it can absorb moisture from the environment.
This can affect flow properties and storage stability.

Proper packaging and dry storage are important.
The compound shows good stability in aqueous solutions over a wide pH range, especially in acidic conditions.
It remains dissolved and available for biological use.

This supports its effectiveness in liquid formulations.
Lysine monohydrochloride plays a role in calcium absorption and utilization in the body.
Lysine monohydrochloride helps improve calcium uptake.

This supports bone health.
Lysine monohydrochloride is involved in collagen formation, contributing to skin, cartilage, and connective tissue structure.
This is important for tissue repair and maintenance.

Lysine monohydrochloride supports overall structural integrity.
Lysine monohydrochloride can influence flavor profiles in food systems, especially when involved in Maillard reactions.
It may contribute to browning and aroma development.

This is relevant in processed foods.
Lysine monohydrochloride is often used in fortification strategies to improve protein quality in plant-based diets.

Lysine monohydrochloride complements amino acid profiles in cereals and grains.
This enhances nutritional value.

Melting point: 263 °C (dec.) (lit.)
alpha: 21 º (c=8, 6N HCl)
Density: 1.28 g/cm³ (20℃)
bulk density: 360 kg/m³
vapor pressure: <1 Pa (20 °C)
FEMA: 3847 | L-LYSINE
storage temp.: 2–8°C
solubility: H2O: 100 mg/mL
form: powder
color: White to Off-white
Odor: odorless
pH: 5.5–6.0 (100 g/L, H2O, 20℃)
biological source: non-animal source
optical activity: [α]20/D +20.5±0.5°, c = 5% in 5 M HCl
Water Solubility: 65 g/100 mL (20 ºC)
λmax: λ: 260 nm Amax: 0.1; λ: 280 nm Amax: 0.1
Merck: 14,5636
BRN: 3563889
Stability: Stable. Incompatible with strong oxidizing agents
Major Application: pharmaceutical (small molecule)
Cosmetics Ingredients Functions: HAIR CONDITIONING; SKIN CONDITIONING
Cosmetic Ingredient Review (CIR): L-Lysine hydrochloride (657-27-2)
InChI: 1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1
InChIKey: BVHLGVCQOALMSV-JEDNCBNOSA-N
SMILES: OC(C@@H
CCCCN)=O.[H]Cl
LogP: -1.036 (est)

Lysine monohydrochloride contains a positively charged ammonium group under physiological conditions, making it highly soluble and reactive in aqueous environments.
This ionic nature enhances its bioavailability.
Lysine monohydrochloride is readily absorbed in biological systems.

The molecule has a long aliphatic side chain ending in an amino group, which distinguishes lysine from other amino acids.
This side chain contributes to its basic character.
Lysine monohydrochloride plays a role in protein structure and interactions.

Lysine monohydrochloride participates in protein synthesis as a building block of peptides and proteins.
It is incorporated into polypeptide chains during translation.
This is essential for growth and tissue repair.

Lysine monohydrochloride is involved in metabolic pathways, including carnitine synthesis.
Carnitine is important for fatty acid metabolism.
This supports energy production in cells.

Lysine monohydrochloride shows acid–base buffering behavior due to its amino and carboxyl groups.
Lysine monohydrochloride can interact with acids and bases in solution.
This is relevant in biochemical systems.

Lysine monohydrochloride may participate in Maillard reactions with sugars during heating.
This can affect color and flavor in food systems.
Lysine monohydrochloride is important in food processing.

The hydrochloride form provides improved stability and handling compared to free lysine.
Lysine monohydrochloride reduces volatility and enhances shelf life.
This makes it suitable for industrial use.

Lysine monohydrochloride is generally compatible with other nutrients and additives in formulations.
It can be combined with vitamins, minerals, and proteins.
This supports nutritional product design.

Lysine monohydrochloride is a bioavailable, water-soluble amino acid salt with essential roles in protein synthesis, metabolism, and nutritional supplementation, widely used in food and feed systems.
Lysine monohydrochloride is generally considered safe and well-tolerated at recommended levels.
Excess intake may lead to mild gastrointestinal effects.

Proper dosage is important.
Lysine monohydrochloride is produced industrially through fermentation processes using microorganisms.
This allows large-scale, cost-effective production.

Lysine monohydrochloride supports global feed and food industries.
Lysine monohydrochloride is a highly soluble, nutritionally essential amino acid salt with roles in metabolism, tissue formation, and food fortification, widely used in health and nutrition applications.

Uses Of Lysine monohydrochloride:
Lysine monohydrochloride is widely used as nutritional supplements in food and beverage industries. 
Lysine monohydrochloride can also be used in animal feed as source of L-Lysine. 
Lysine monohydrochloride can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Lysine monohydrochloride is widely used as a feed additive in animal nutrition.
It supplements lysine deficiency in diets, especially for poultry and swine.
This improves growth, feed efficiency, and protein utilization.

In food products, it is used as a nutritional fortifier.
Lysine monohydrochloride enhances the amino acid profile of cereals and plant-based foods.
This improves overall protein quality.

Lysine monohydrochloride is used in dietary supplements.
It provides essential lysine for human health.
This supports muscle growth, immune function, and tissue repair.

In pharmaceutical formulations, it is used as an active ingredient or excipient.
Lysine monohydrochloride supports therapeutic applications and formulation stability.
This contributes to health-related products.

Lysine monohydrochloride is applied in clinical nutrition and medical foods.
It helps address amino acid deficiencies.
This supports patient recovery and specialized diets.

In fortified beverages and functional foods, it is added to improve nutritional value.
Lysine monohydrochloride dissolves easily in water-based systems.
This supports convenient consumption.

Lysine monohydrochloride is used in fermentation and biotechnology processes as a nutrient source.
Lysine monohydrochloride supports microbial growth and metabolism.
This aids industrial production.

In cosmetic and personal-care formulations, it may be used as a conditioning or functional ingredient.
Lysine monohydrochloride contributes to skin and hair care benefits.
This enhances product performance.

Lysine monohydrochloride is also used in pet food formulations to ensure balanced nutrition.
It supports healthy growth and development in animals.
Lysine monohydrochloride is used wherever protein fortification, amino acid supplementation, and nutritional balance are required across food, feed, pharmaceutical, and biotechnology applications.

Lysine monohydrochloride is widely used as a feed additive in animal nutrition.
It supplements lysine deficiency in diets, especially for poultry and swine.
This improves growth, feed efficiency, and protein utilization.

In food products, it is used as a nutritional fortifier.
Lysine monohydrochloride enhances the amino acid profile of cereals and plant-based foods.
This improves overall protein quality.

Lysine monohydrochloride is used in dietary supplements.
It provides essential lysine for human health.
This supports muscle growth, immune function, and tissue repair.

In pharmaceutical formulations, it is used as an active ingredient or excipient.
Lysine monohydrochloride supports therapeutic applications and formulation stability.
This contributes to health-related products.

Lysine monohydrochloride is applied in clinical nutrition and medical foods.
It helps address amino acid deficiencies.
This supports patient recovery and specialized diets.

In fortified beverages and functional foods, it is added to improve nutritional value.
Lysine monohydrochloride dissolves easily in water-based systems.
This supports convenient consumption.

Lysine monohydrochloride is used in fermentation and biotechnology processes as a nutrient source.
It supports microbial growth and metabolism.
This aids industrial production.

In cosmetic and personal-care formulations, it may be used as a conditioning or functional ingredient.
Lysine monohydrochloride contributes to skin and hair care benefits.
This enhances product performance.

Lysine monohydrochloride is also used in pet food formulations to ensure balanced nutrition.
It supports healthy growth and development in animals.
Lysine monohydrochloride is used wherever protein fortification, amino acid supplementation, and nutritional balance are required across food, feed, pharmaceutical, and biotechnology applications.

Safety Profile Of Lysine monohydrochloride:
Lysine monohydrochloride is hazardous by inhalation. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Lysine monohydrochloride is generally considered to have low hazard potential, especially at levels used in food and feed applications.
It is an essential amino acid and widely regarded as safe.

However, handling of concentrated material requires standard precautions.
Skin contact is typically low risk, but prolonged exposure to powder may cause mild irritation or dryness.
Sensitive individuals may experience slight redness.

Protective gloves are recommended in industrial handling.
Eye contact may cause mild irritation.
Symptoms can include redness, watering, and discomfort.

Eyes should be rinsed with water if exposure occurs.
Inhalation of dust may cause respiratory irritation, particularly in powder-processing environments.
Symptoms can include coughing or throat irritation.

Adequate ventilation and dust control are recommended.
Ingestion is generally safe at normal dietary levels, but excessive intake may cause gastrointestinal discomfort.
Symptoms can include nausea or diarrhea.

Recommended intake levels should be followed.
Lysine monohydrochloride is not flammable under normal conditions, but fine powder may present a dust explosion risk in industrial settings.
Proper dust handling and explosion prevention measures are important.

Standard fire safety precautions should be applied.
The compound is chemically stable under normal storage conditions, but it is hygroscopic and may absorb moisture.

Lysine monohydrochloride should be stored in a cool, dry place.
Proper storage maintains quality and flow properties.

 

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