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Monosodium lactate has antimicrobial and antioxidant effects.
Monosodium lactate is used as a food additive as a safe organic preservative for fish, sausage, etc.
Monosodium lactate is a naturally occurring humectant that is an extremely effective moisturizer.
CAS: 72-17-3
MF: C3H5NaO3
MW: 112.06
EINECS: 200-772-0
Synonyms
LACTIC ACID SODIUM SALT;2-hydroxy-propanoicacimonosodiumsalt;(+/-)-2-HYDROXYPROPIONIC ACID SODIUM SALT;SODIUM DL-LACTATE SOLUTION;SODIUM DL-LACTATE;lacolin;lacticacid,monosodiumsalt;(±)-2-Hydroxypropionic acid sodium salt, DL-Lactic acid sodium salt
Monosodium lactate could be used in cosmetics, such as aftershave lotion.
Monosodium lactate is also advocated in the treatment of bradyeardia and asystole associated with complete heart block.
Monosodium lactate is the sodium salt of lactic acid that has a mild saline taste.
Monosodium lactate is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3
As early as 1836, Monosodium lactate was recognized as a salt of a weak acid rather than being a base, and it was then known that the lactate had to be metabolized in the liver before the sodium could have any titrating activity.
An organic Monosodium lactate having lactate as the counterion.
Monosodium lactate is an organic, sodium salt of lactic acid.
Monosodium lactate is a hygroscopic agent and a component of natural moisturizing factor (NMF).
Monosodium lactate is usually produced by fermentation.
Monosodium lactate is a liquid or powder salt of lactic acid produced by fermenting sugar sources like corn or beets.
Monosodium lactate acts as a preservative, pH regulator, and humectant in food (especially meats) and cosmetics.
Monosodium lactate is known for its high-performance moisturizing properties and antimicrobial action.
Monosodium lactate is the sodium salt of lactic acid, and has a mild saline taste.
Monosodium lactate is produced by fermentation of a sugar source, such as maize (corn) or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Monosodium lactate, in the form of Ringer's lactate solution, is used as a medication, and is included on the World Health Organization's List of Essential Medicines.
Monosodium lactate, with the CAS number 867-56-1, is the sodium salt of L-lactic acid, a compound that plays a significant role in various biochemical processes.
Monosodium lactate appears as a white, hygroscopic powder that is soluble in water, making it useful in various applications.
Monosodium lactate is often utilized in the food industry as a preservative and flavoring agent due to its ability to enhance the shelf life of products and impart a mild acidity.
In the pharmaceutical and cosmetic industries, Monosodium lactate serves as a moisturizer and pH regulator.
Biochemically, Monosodium lactate is involved in metabolic processes and can act as an electrolyte replenisher.
Monosodium lactate is generally recognized as safe (GRAS) when used in appropriate amounts.
Monosodium lactate's properties include a slightly sweet taste and a low toxicity profile, making it suitable for various applications in food, medicine, and personal care products.
Additionally, Monosodium lactate can be used in laboratory settings for cell culture and as a buffering agent.
Monosodium lactate Chemical Properties
Melting point: 17°C
Boiling point: 110°C
density: 1.33
vapor density: 0.7 (vs air)
vapor pressure: 17.535 mm of Hg (@ 20°C)
refractive index: 1.422-1.425
storage temp.: 2-8°C
solubility: Miscible with ethanol (95%), and with water.
form: syrup
color: Light Yellow
PH: pH (7→35, 25℃) : 6.5～7.5
Odor: Odorless
PH Range: 6.5 - 8.5
biological source: synthetic
Water Solubility: miscible
Merck: 14,8635
BRN: 4332999
Stability: Stable.
Cosmetics Ingredients Functions: KERATOLYTIC
BUFFERING
HUMECTANT
InChI: 1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1
InChIKey: NGSFWBMYFKHRBD-UHFFFAOYSA-M
LogP: -0.698 (est)
CAS DataBase Reference: 72-17-3(CAS DataBase Reference)
EPA Substance Registry System: Monosodium lactate (72-17-3)
Monosodium lactate occurs as a clear, colorless, slightly syrupy liquid.
Monosodium lactate is odorless, or has a slight odor with a characteristic saline taste.
Monosodium lactate is hygroscopic.
Monosodium lactate is an alkalinizing agent.
Monosodium lactate is a racemic salt; the l-isomer is oxidized in the liver to bicarbonate and the d-isomer is converted to glycogen.
Monosodium lactate solution is an aqueous solution containing not less than 50% w/w of monosodium lactate.
The solution occurs as a clear, colorless or practically colorless, slightly viscous liquid that has a slight, not unpleasant odor.
Monosodium lactate solution is miscible with water.
The solution has a pH of 5-9. Sodium lactate solution is used in the preparation of sodium lactate injection and lactated Ringer's injection.
Monosodium lactate injection is a sterile sodium lactate solution in water for injection, or a sterile solution of lactic acid in water for injection prepared with the aid of sodium hydroxide.
Monosodium lactate, sodium hydroxide, or hydrochloric acid may be added during the manufacture of the injection to adjust the pH to 6-7.3.
Monosodium lactate is also available as a small volume parenteral additive solution which provides 5.6 g of sodium lactate and 50 mEq each of sodium and lactate ions per 20 mL; diluting 50 mEq of Monosodium lactate to 300 mL with a nonelectrolyte solution or sterile water for injection results in a (1/6) M (approximately isotonic) sodium lactate (1.9%) solution.
One-sixth molar ((1/6) M) sodium lactate (1.9%) contains approximately 18.7 g/L or about 167 mEq of sodium and 167 mEq of lactate ions per liter, and about 55 calories/L.
(1/6) M Sodium lactate injection has a calculated osmolarity of about 330 mOsm/L.
Each liter of (1/6) M sodium lactate solution is potentially equivalent in acid-neutralizing effect to 340 mL of a 5% sodium bicarbonate solution.
Uses
The sodium salt of lactic acid (L113490).
Monosodium lactate acts as a preservative, acidity regulator, and bulking agent.
Instead of glycerol in calico printing; as a plasticizer for casein; as a corrosion inhibitor in alcohol antifreeze mixture.
As a food additive, Monosodium lactate has the E number E325 and is naturally a liquid product, but also is available in powder form.
Monosodium lactate acts as a preservative, acidity regulator, and bulking agent.
Monosodium lactate is sometimes used in shampoo products and other similar items such as liquid soaps as it is an effective humectant and moisturizer.
Monosodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension.
Monosodium lactate also can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously impaired.
However, the use in lactic acidosis is contraindicated.
Food industry
As a food additive, Monosodium lactate has the E number E325 and is naturally a liquid product, but also is available in powder form.
Monosodium lactate acts as a preservative, acidity regulator, and bulking agent.
Despite the similarity in name, Monosodium lactate itself is not chemically similar to lactose (milk sugar), so need not be restricted by those with lactose intolerance.
Cosmetics and personal care products
Monosodium lactate is sometimes used in shampoo products and other similar items such as liquid soaps, as it is an effective humectant and moisturizer.
Medical use
Monosodium lactate is used to treat arrhythmias caused by overdosing of class I antiarrythmics, as well as pressor sympathomimetics which can cause hypertension.
Monosodium lactate can be given intravenously as a source of bicarbonate for preventing or controlling mild to moderate metabolic acidosis in patients with restricted oral intake (for sodium bicarbonate) whose oxidative processes are not seriously impaired.
However, the use in lactic acidosis is contraindicated.
Monosodium lactate may induce panic attacks in persons with existing panic disorder; up to 72% of individuals with panic disorder experience a panic attack when administered sodium lactate intravenously.
Monosodium lactate may therefore also be used to confirm a diagnosis of panic disorder.
In 2022, it was the 287th most commonly prescribed medication in the United States, with more than 500,000 prescriptions.
Pharmaceutical Applications
Monosodium lactate is widely used in cosmetics, food products and pharmaceutical applications including parenteral and topical formulations.
Therapeutically, Monosodium lactate is used in infusions as a component of Ringer-lactate solution; as an alternative for sodium hydrogencarbonate in light acidosis; as a rehydrating agent; and as a carrier for electrolyte concentrates or medicines in perfusion/ infusion solutions.
Biochem/physiol Actions
Monosodium lactate functions as a buffer to maintain osmotic and charge balance.
Monosodium lactate serves as a humectant, especially in cosmetic preparations.
Monosodium lactate acts a flavoring agent in meat and poultry products.
Monosodium lactate also plays a role as a buffer. Sodium lactate could be an alternative source of energy and an oxidative substrate in case of lack of oxygen in brain cells.
Food additive
Monosodium lactate need not be restricted by someone avoiding milk or those with a milk allergy.
In general, lactates such as sodium, calcium, and potassium lactate are salts derived from the neutralization of lactic acid and most commercially used lactic acids are fermented from dairy - free products such as cornstarch, potatoes, or molasses.
Sugar or tapioca additionally may be used.
However some lactic acid is fermented from dairy products such as whey and lactose.
Whey is made of up 6.5 % solids of which 4.8% is solid lactose.
Waste whey typically is used to produce lactic acid when the whey itself is produced as waste during the manufacture of certain dairy products.
As a result, such dairy-type lactic acid generally goes back into dairy products, such as ice cream and cream cheese, rather than into non - dairy products.
Moreover, although the lacticacid starter culture to ferment corn or beets may contain milk, Monosodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy.
Production
In general, lactates such as sodium, calcium, and potassium lactate are salts derived from the neutralization of lactic acid and most commercially used lactic acids are fermented from dairy-free products such as cornstarch, potatoes, or molasses.
Sugar or tapioca additionally may be used.
In some rare instances, some Monosodium lactate is fermented from dairy products such as whey and lactose.
Whey is made of up 6.5% solids of which 4.8% is solid lactose.
Waste whey is infrequently used to produce Monosodium lactate when the whey itself is produced as waste during the manufacture of certain dairy products.
Such dairy-type lactic acid generally goes back into dairy products, such as ice cream and cream cheese, rather than into non-dairy products.
Moreover, although the lactic-acid starter culture to ferment corn or beets may contain milk, sodium lactate does not contain milk protein and need not be restricted by someone avoiding milk or those with a milk allergy.
