MORFOLIN

MORFOLIN

CAS: 110-91-8
EC NUMARASI: 203-815-1

SINONIMY:
MORPHOLINE; 110-91-8; 1-Oxa-4-azacyclohexane; Tetrahydro-1,4-oxazine; Diethylene oximide; Diethylenimide oxide; Diethyleneimide oxide; Drewamine; Diethylene imidoxide; morpholin; Tetrahydro-2H-1,4-oxazine; Tetrahydro-p-oxazine; p-Isoxazine, tetrahydro-; Tetrahydro-1,4-isoxazine; BASF 238; Caswell No. 584; Morpholine, 4-soya alkyl derivs.; 2H-1,4-Oxazine, tetrahydro-; 4H-1,4-Oxazine, tetrahydro-; NSC 9376; UNII-8B2ZCK305O; CCRIS 2482; HSDB 102; EINECS 203-815-1; UN2054; C4H9NO; EPA Pesticide Chemical Code 054701; BRN 0102549; Tetrahydro-4H-1-4-oxazine; AI3-01231; 8B2ZCK305O; CHEBI:34856; MFCD00005972; 61791-40-0; Morpholine [UN2054] [Flammable liquid]; DSSTox_CID_5688; DSSTox_RID_77880; DSSTox_GSID_25688; Morpholine, 99+%, extra pure; Morpholine, 99+%, ACS reagent; CAS-110-91-8; MORPHOLINE,REAG; Tetrahydro-p-isoxazine; MORPHOLINE, PRACT; morphline; Morpholine, 99.5%, purified by redistillation, AcroSeal(R); morpho line; morpholine-; EINECS 263-172-8; 4H-1, tetrahydro-; PubChem15002; Morpholine Reagent Grade; Morpholine on Rasta Resin; WLN: T6M DOTJ; 1,4$l^{2}-oxazinane; EC 203-815-1; NCIMech_000154; Tetrahydro-1, 4-isoxazine; NCIOpen2_007748; Oprea1_317540; Tetryhydro-2H-1,4-oxazine; Tetrahydro-4H-1,4-Oxazine; 4-27-00-00015 (Beilstein Handbook Reference); KSC175A0J; BIDD:ER0297; ACMC-20997q; Morpholine, analytical standard; CHEMBL276518; DTXSID2025688; CTK0H5004; NSC9376; BCP24054; NSC-9376; STR00194; ZINC1699948; Tox21_202450; Tox21_303240; ANW-16212; STL182843; AKOS000118829; Morpholine, ACS reagent, >=99.0%; Morpholine, ReagentPlus(R), >=99%; DB13669; MCULE-4684386765; NA 2054; NE10420; UN 2054; KS-00000V97; NCGC00249227-01; NCGC00256942-01; NCGC00259999-01; SC-19088; Morpholine, p.a., ACS reagent, 99.0%; DB-030063; Morpholine [UN2054] [Flammable liquid]; FT-0628993; M0465; NS00010190; Morpholine purified by distillation from glass; 1031-EP2269992A1; 1031-EP2269993A1; 1031-EP2270004A1; 1031-EP2270006A1; 1031-EP2270010A1; 1031-EP2270113A1; 1031-EP2272509A1; 1031-EP2272517A1; 1031-EP2272813A2; 1031-EP2272817A1; 1031-EP2272827A1; 1031-EP2272832A1; 1031-EP2272834A1; 1031-EP2272835A1; 1031-EP2272839A1; 1031-EP2272840A1; 1031-EP2272841A1; 1031-EP2272844A1; 1031-EP2272848A1; 1031-EP2272849A1; 1031-EP2272935A1; 1031-EP2272972A1; 1031-EP2272973A1; 1031-EP2274983A1; 1031-EP2275102A1; 1031-EP2275395A2; 1031-EP2275401A1; 1031-EP2275403A1; 1031-EP2275404A1; 1031-EP2275410A1; 1031-EP2275411A2; 1031-EP2275413A1; 1031-EP2275422A1; 1031-EP2277848A1; 1031-EP2277858A1; 1031-EP2277872A1; 1031-EP2277877A1; 1031-EP2277880A1; 1031-EP2277881A1; 1031-EP2280001A1; 1031-EP2280004A1; 1031-EP2280005A1; 1031-EP2280006A1; 1031-EP2280008A2; morpholine; Morfolin; Morpholine; MORPHOLIN; morfoline; MorphoLine; 1031-EP2305219A1; 1031-EP2305250A1; 1031-EP2305629A1; 1031-EP2305633A1; 1031-EP2305648A1; 1031-EP2305651A1; 1031-EP2305652A2; 1031-EP2305672A1; 1031-EP2305674A1; 1031-EP2305675A1; 1031-EP2305677A1; 1031-EP2305679A1; 1031-EP2305682A1; 1031-EP2305687A1; 1031-EP2305695A2; 1031-EP2305696A2; 1031-EP2305697A2; 1031-EP2305698A2; 1031-EP2308479A2; 1031-EP2308509A1; 1031-EP2308510A1; 1031-EP2308562A2; 1031-EP2308812A2; 1031-EP2308833A2; 1031-EP2308838A1; 1031-EP2308839A1; 1031-EP2308840A1; 1031-EP2308849A1; 1031-EP2308850A1; 1031-EP2308854A1; 1031-EP2308857A1; 1031-EP2308861A1; 1031-EP2308867A2; 1031-EP2308868A1; 1031-EP2308870A2; 1031-EP2308879A1; 1031-EP2308880A1; 1031-EP2309584A1; 1031-EP2311451A1; 1031-EP2311455A1; 1031-EP2311464A1; 1031-EP2311796A1; 1031-EP2311797A1; 1031-EP2311798A1; 1031-EP2311799A1; 1031-EP2311802A1; 1031-EP2311803A1; 1031-EP2311808A1; 1031-EP2311810A1; 1031-EP2311815A1; 1031-EP2311825A1; 1031-EP2311827A1; 1031-EP2311829A1; 1031-EP2311842A2; 1031-EP2314295A1; 1031-EP2314574A1; 1031-EP2314575A1; 1031-EP2314586A1; 1031-EP2314587A1; 1031-EP2314588A1; 1031-EP2314590A1; 1031-EP2316450A1; 1031-EP2316459A1; 1031-EP2316470A2; 1031-EP2316831A1; 1031-EP2316832A1; 1031-EP2316833A1; 1031-EP2316974A1; 1031-EP2371811A2; 1031-EP2371831A1; 1031-EP2372804A1; 1031-EP2374454A1; 1031-EP2378585A1; 1031-EP2380872A1; 1031-EP2380874A2; C14452; 59619-EP2275422A1; 59619-EP2292589A1; 59619-EP2295436A1; 59619-EP2295439A1; 59619-EP2298076A1; 59619-EP2298077A1; 59619-EP2298305A1; 59619-EP2298762A2; 59619-EP2301353A1; 59619-EP2305031A1; 59619-EP2305034A1; 59619-EP2305035A1; 59619-EP2308852A1; 59619-EP2371823A1; Morpholine, purified by redistillation, >=99.5%; Q410243; J-522715; 1-Oxa-4-azacyclohexane ; Tetrahydro-2H-1,4-oxazine; F2190-0339; 6LR; Morpholine, polymer-bound, 200-400 mesh;

Morfolin - eto organicheskoye khimicheskoye soyedineniye, imeyushcheye khimicheskuyu formulu O (CH2CH2) 2NH. Etot geterotsikl soderzhit kak aminnyye, tak i prostyye efirnyye funktsional'nyye gruppy. Iz-za amina morfolin yavlyayetsya osnovaniyem; yego sopryazhennaya kislota nazyvayetsya morfoliniy. Naprimer, obrabotka morfolina solyanoy kislotoy privodit k obrazovaniyu soli khlorida morfoliniya.

Predpochtitel'noye nazvaniye IUPAC:
Morfolin
Drugiye imena:
Dietilenimid oksid
1,4-oksazinan
Tetragidro-1,4-oksazin
Dietilen imidoksid
Dietilenoksimid
Tetragidro-p-oksazin
Khimicheskaya formula:
C4H9NO
Molyarnaya massa:
87,122 g · mol' − 1
Vneshnost':
Bestsvetnaya zhidkost'
Zapakh:
Slabyy ammiachnyy ili rybnyy [2]
Plotnost':
1,007 g / sm3
Temperatura plavleniya:
-5 ° S (23 ° F, 268 K)
Tochka kipeniya:
129 ° S (264 ° F, 402 K)
Rastvorimost' v vode:
Smeshivayemyy

Prilozheniya

Morfolin chasto poluchayut promyshlennym sposobom putem degidratatsii dietanolamina sernoy kislotoy. Morfolin - obychnaya dobavka, v kontsentratsiyakh millionnykh doley, dlya regulirovaniya pH kak v iskopayemom toplive, tak i v parovykh sistemakh atomnykh elektrostantsiy. Morfolin ispol'zuyetsya, potomu chto yego letuchest' primerno takaya zhe, kak u vody, poetomu posle dobavleniya v vodu yego kontsentratsiya stanovitsya dovol'no ravnomerno raspredelennoy kak v vodnoy, tak i v parovoy fazakh. Zatem yego svoystva regulirovaniya pH raspredelyayutsya po vsey parovoy ustanovke, obespechivaya zashchitu ot korrozii. Morfolin chasto ispol'zuyetsya v sochetanii s gidrazinom ili ammiakom v nizkikh kontsentratsiyakh, chtoby obespechit' kompleksnuyu khimicheskuyu obrabotku letuchikh veshchestv dlya zashchity ot korrozii parovykh sistem takikh ustanovok. Morfolin razlagayetsya dostatochno medlenno v otsutstviye kisloroda pri vysokikh temperaturakh i davleniyakh v etikh parovykh sistemakh.

Organicheskiy sintez

Morfolin preterpevayet bol'shinstvo khimicheskikh reaktsiy, tipichnykh dlya drugikh vtorichnykh aminov, khotya prisutstviye kisloroda prostogo efira otnimayet u azota elektronnuyu plotnost', delaya yego meneye nukleofil'nym (i meneye osnovnym), chem strukturno podobnyye vtorichnyye aminy, takiye kak piperidin. Po etoy prichine on obrazuyet stabil'nyy khloramin. Obychno on ispol'zuyetsya dlya polucheniya yenaminov. Morfolin shiroko ispol'zuyetsya v organicheskom sinteze. Naprimer, on yavlyayetsya stroitel'nym blokom pri prigotovlenii antibiotika linezolida, protivorakovogo agenta gefitiniba (iressa) i obezbolivayushchego dekstromoramida. V issledovaniyakh i v promyshlennosti nizkaya stoimost' i polyarnost' morfolina obuslavlivayut yego shirokoye ispol'zovaniye v kachestve rastvoritelya dlya khimicheskikh reaktsiy.

sel'skoye khozyaystvo
Morfolin ispol'zuyetsya v kachestve khimicheskogo emul'gatora v protsesse voskovoy obrabotki fruktov. Yestestvenno, frukty proizvodyat vosk dlya zashchity ot nasekomykh i gribkovogo zarazheniya, no on mozhet byt' poteryan pri ochistke fruktov. Vmesto nego nanositsya nebol'shoye kolichestvo novogo voska. Morfolin ispol'zuyetsya v kachestve emul'gatora i sredstva dlya povysheniya rastvorimosti shellaka, kotoryy ispol'zuyetsya v kachestve voska dlya pokrytiya fruktov. Yevropeyskiy Soyuz zapretil ispol'zovaniye morfolina dlya pokrytiya fruktov.

Moyushcheye sredstvo morfolina
On ispol'zuyetsya v kachestve dobavki v opticheskikh otbelivatelyakh dlya otbelivaniya khlorom dlya ispol'zovaniya v moyushchikh sredstvakh.
Kosmetika morfolina
Ispol'zuyetsya v solyakh zhirnykh kislot dlya sozdaniya vodostoykikh emul'gatorov i plastifikatorov v kosmeticheskikh produktakh. On takzhe ispol'zuyetsya v kachestve promezhutochnogo soyedineniya v solyakh chetvertichnogo morfoliniya dlya konditsionerov dlya volos i dezodoriruyushchikh sredstv.
Lekarstvo morfolina
Lekarstvennyye preparaty (anal'getiki, anestetiki saranchi, antibiotiki, antimikotiki i antiplat) ispol'zuyutsya v kachestve promezhutochnykh produktov pri proizvodstve produktov.
Morfolin - boleye slaboye osnovaniye. Temperatura plavleniya sostavlyayet -5 ° C, a temperatura kipeniya sostavlyayet 129 ° C. Plotnost' sostavlyayet 0,999 g / ml. Morfolin - gigroskopichnaya zhidkost', kotoruyu mozhno smeshivat' s vodoy i mnogimi organicheskimi rastvoritelyami. Kharakternyy aminnyy zapakh Imeyet. V normal'nykh usloviyakh morfolin, obladayushchiy vysokoy stabil'nost'yu, razlagayetsya v kontse peregreva i vosplamenyayetsya, kogda obrazuyet oksid azota, vstupaya v tyazheluyu reaktsiyu s sil'nymi okislitelyami. Eto ochen' stabil'naya i poleznaya molekula.

Morfolin - prozrachnaya bestsvetnaya letuchaya gigroskopichnaya zhidkost' s kharakternym zapakhom amina. Smeshivayetsya s vodoy i bol'shinstvom organicheskikh rastvoriteley. Smes' morfolina i vody ne imeyet postoyannoy temperatury kipeniya. Sledovatel'no, morfolin v vodnom rastvore nelegko otdelit' otgonkoy ili unosom. Eto geterotsiklicheskoye khimicheskoye soyedineniye, kotoroye imeyet kak vtorichnuyu aminnuyu, tak i prostuyu efirnuyu funktsional'nuyu gruppu; yego molekula imeyet strukturu stula. Morfolin khimicheski stabilen i, kak ozhidayetsya, ne razlagayetsya v goryachey vode, rastvorakh kislot i shchelochey. Obrazuyet soli morfoliniya s mineral'nymi kislotami. On reagiruyet s al'degidami i ketonami s atomami vodoroda v al'fa-polozhenii s obrazovaniyem yenaminov.