N-DODECYL MERCAPTAN

N-DODECYL MERCAPTAN

CAS No. : 112-55-0
EC No. : 203-984-1

Synonyms:
1-Dodecanethiol; n-Dodecyl mercaptan; Dodecyl mercaptan; Lauryl mercaptan; Mercaptan C12; NDM; n dodecyl mercaptan; n-dodesil merkaptan; DDT; lauryl mercaptan; NDDM; 1-DODECANETHIOL; Dodecane-1-thiol; 112-55-0; Dodecyl mercaptan; Dodecanethiol; n-Dodecanethiol; Lauryl mercaptan; n-Dodecyl mercaptan; N-Dodecylmercaptan; 1-Mercaptododecane; n-Lauryl mercaptan; 1-Dodecyl mercaptan; Dodecylmercaptan; Pennfloat M; Pennfloat S; n-Dodecylthiol; 1-dodecylthiol; Lauryl mercaptide; M-Lauryl mercaptan; M-Dodecyl mercaptan; Dodecylthiol; Dodecyl mercaptan (VAN); NSC 814; NCI-C60935; UNII-S8ZJB6X253; CCRIS 743; HSDB 1074; EINECS 203-984-1; 1322-36-7; 1-Dodecanethiol, 98%; Tris(dodecylthio)antimony; CAS-112-55-0; 1-Dodecanethiol, antimony(3+) salt; dodecanthiol; laurylmercaptan; dodecane thiol; 1-dodecanthiol; dodecyl-mercaptan; 1-dodecane thiol; 1-dodecylmercaptan; n-dodecyl-mercaptan; Dodecanethiol-(1); normal dodecylmercaptan; normal dodecyl mercaptan; ACMC-1CUIY; EC 203-984-1; 1-Dodecanethiol, >=98%; ZINC59144932; WLN:; 1-Dodecanethiol, purum, >=97.0% (GC); 1-Dodecanethiol, telomer with 1,3-butadiene and ethenylbenzene; 1,3-Butadiene, styrene, telomer with 1-dodecanethiol; 2-Methylundecane-2-thiol; 10059-13-9; DDT; dodecane mercaptan; n-DDM; dodecane thiol EINECS 233-191-6; 2-Undecanethiol, 2-methyl-; tert-Dodecyl mercaptane; 2-Nonyl-2-propanethiol; 2-Methylundecyl-2-thiol; tertiary dodecyl mercaptan; 2-methyl-2-undecanethiol; 2-methyl-undecane-2-thiol; allyl mercaptan; amyl mercaptan; isoamyl mercaptan; sec-amyl mercaptan; tert-amyl mercaptan; benzyl mercaptan; buchu mercaptan; butyl mercaptan; isobutyl mercaptan; tert-butyl mercaptan; cetyl mercaptan; cyclohexyl mercaptan; cyclopentyl mercaptan; decyl mercaptan; 2-ethyl hexyl mercaptan; ethyl mercaptan; ethylene mercaptan; furfuryl mercaptan; grapefruit mercaptan; heptyl mercaptan; hexyl mercaptan; 1-Dodecanethiol; n-Dodecyl mercaptan; Dodecyl mercaptan; Lauryl mercaptan; Mercaptan C12; NDM; n dodecyl mercaptan; n-dodesil merkaptan; DDT; methyl mercaptan; 2-naphthyl mercaptan; nonyl mercaptan; octyl mercaptan; peach mercaptan; n-Dodecanethiol; n-Dodecyl mercaptan; n-Lauryl mercaptan; Dodecane-1-thiol; Dodecyl mercaptan; Lauryl mercaptan; 1-Dodecyl mercaptan; 1-Mercaptododecane; Dodecylthiol; Dodecanethiol-(1); NCI-C60935; Pennfloat M; Pennfloat S; n-Dodecylthiol; 1-Dodecylthiol; NSC 814; 1-phenethyl mercaptan; 2-phenethyl mercaptan; phenyl mercaptan; prenyl mercaptan; propyl mercaptan; isopropyl mercaptan; 2-thienyl mercaptan; 3-thienyl mercaptan; tridecyl mercaptan; undecyl mercaptan; Pennfloat M; Pennfloat S; n-Dodecylthiol; 1-dodecylthiol; Lauryl mercaptide; M-Lauryl mercaptan; M-Dodecyl mercaptan; Dodecylthiol; Dodecyl mercaptan; 2-Undecanethiol,2-methyl-; SCHEMBL21128; 1,1-Dimethyl-decyl-mercaptan; SCHEMBL564605; 1,1-Dimethyldecyl hydrosulfide #; Tert-dodecylmercaptan 25103-58-6; n-DDM

N-Dodecyl Mercaptan

N-Dodecyl mercaptan (DDT) is an alkyl thiol that forms a self-assembled monolayer (SAM) and can be used as an organic source of sulfur with balanced physio-chemical properties.
NDM (NORMAL DODECYL MERCAPTAN) is commonly used in the manufacturing process of polymers such as styrenics and acrylics (PMMA, ABS...).

Application
N-Dodecyl mercaptan can be used as a source of sulfur for the synthesis CdS quantum dots (QDs) and lead sulfide nanoparticles (PbS) which find potential applications in energy efficient lighting, solar cells and as ammonium gas sensing agents. N-Dodecyl mercaptan may be used to form a self-assembled monolayer (SAM) on copper surface as a corrosion resistant coating. Functionalization with N-Dodecyl mercaptan may form SAMs on geranium (Ge) to improve the surface characteristics for futuristic applications in microelectronics.
This molecule is used for the production of hydrophobic SAMs. N-Dodecyl mercaptan can also be used in mixed SAMs to give a hydrophobic background and act as a spacer to move other functional groups or domains farther apart.

Polymers and Rubber Applications
Normal dodecyl mercaptan (n-dodecyl mercaptan, 1-dodecanethiol, lauryl mercaptan, NDDM, CAS # 112-55-0) is used as reactants in the synthesis of antioxidants, which minimize undesirable effects from processes such as the stabilization of tin.
Applications
Additives
Antioxidants
Lubricants
Polymers

N-Dodecyl mercaptan is not soluble in water, slightly soluble in light alcohols and soluble in styrene and most organic solvents.
N-Dodecyl Mercaptan is used in lubricant intermediate to produce additives and final components. At the same time is it also used for polymers and rubber applications.
N-Dodecyl Mercaptan is used in lubricant intermediates to produce additives as well as final components to improve lubricant performance in base oils and metal working fluids. Moreover Normal Dodecyl Mercaptan ( 1-dodecanethiol, lauryl mercaptan, NDDM) is used as reactants in the synthesis of antioxidants, which minimize undesirable effects from processes such as the stabilization of tin.

Product Specifications
Physical state : Liquid
Color : Colorless
Odor : Repulsive
Flash point : 133 °C
Oxidizing properties : no
Autoignition temperature : 230 °C
Molecular formula : C12H26S
Molecular weight : 202,44 g/mol
pH : Not applicable
Boiling point/boiling range : 270 °C
Vapor pressure : 0,00 mbar at 25 °C
Water solubility : 0,0054 mg/l
Method: OECD Test Guideline 105
Viscosity, dynamic : 2,98 cP at 25 °C
Relative vapor density : 1 (Air = 1.0)
Primary Chemistry: N-DODECYL MERCAPTAN

Applications
Lubricant Additive, Pharmaceutical Additives, Antioxidant Intermediates, Polymer Modifiers
N-dodecyl mercaptan is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).

Teratogenicity was evaluated in pregnant female Charles River CD-1 mice (25/group) exposed by inhalation to n-dodecyl mercaptan at concentrations of 0 and 7.4 ppm for 6 hrs/day on gestation days (GD) 6-16. Cesarean sections were performed on all surviving mice on GD 17. Significant differences were observed between treated and control animals in the following: maternal mortality (19 mice died on GD 13-16, one was sacrificed in extremis on GD 16, remaining mice, which exhibited signs of extreme toxicity, were sacrificed on GD 15-16), necropsy observations (including black discoloration of the intestines, colored fluid in the stomach or intestines, and absence of stomach contents), and incidence of whole litter resorptions (7 of 20 gravid females). Since no treated animals survived to the end of the study, no comparisons between treated and control animals can be made with respect to: maternal body weight and weight gain (weight loss was observed in treated animals), GD 17 Cesarean observations, and fetal morphological examination (since the fetuses were obtained prematurely, the skeletons were partially- or non-ossified).

Teratogenicity was evaluated in pregnant female Charles River COBS CD rats (25/group) exposed by inhalation to n-dodecyl mercaptan at concentrations of 0 and 7.4 ppm for 6 hrs/day on gestation days (GD) 6-19. Cesarean sections were performed on all surviving mice on GD 20. Significant differences were observed between treated and control animals in the following: increased incidence of hair loss, reddened conjunctivae, dry brown or black material around the nose, dry, peeling skin, thinness, and a pronounced reduction in maternal body weight gain. No significant differences were observed between treated and control animals in the following: necropsy examination, mean number of viable fetuses, postimplantation loss, total implantations, corpora lutea, fetal body weight, fetal sex ratio, fetal malformations, and genetic and developmental variations.

Environmental Fate/Exposure Summary
N-dodecyl mercaptan's production and use in pharmaceuticals, insecticides, nonionic detergents, synthetic rubber processing, and as a froth flotation agent for metal refining may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 8.53X10-3 mm Hg at 25 °C indicates N-dodecyl mercaptan will exist solely as a vapor in the ambient atmosphere. Vapor-phase N-dodecyl mercaptan will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 7 hours. N-dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight. If released to soil, N-dodecyl mercaptan is expected to be immobile based upon an estimated Koc of 1.1X10+4. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 5.9X10-2 atm-cu m/mole. However, adsorption to soil is expected to attenuate volatilization. Biodegradation data were not available. If released into water, N-dodecyl mercaptan is expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 4 hours and 6 days, respectively. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 77 days if adsorption is considered. An estimated BCF of 360 suggests the potential for bioconcentration in aquatic organisms is moderate. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to N-dodecyl mercaptan may occur through inhalation and dermal contact with this compound at workplaces where N-dodecyl mercaptan is produced or used. The greatest potential for dermal and inhalation exposure to N-dodecyl mercaptan is expected at the packing station at the manufacturing site and to a lesser extent during activities at the consumer site.

N-dodecyl mercaptan's production and use in pharmaceuticals, insecticides, nonionic detergents, synthetic rubber processing, and as a froth flotation agent for metal refining(1) may result in its release to the environment through various waste streams(SRC).
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.1X10+4(SRC), determined from a structure estimation method(2), indicates that N-dodecyl mercaptan is expected to be immobile in soil(SRC). Volatilization of N-dodecyl mercaptan from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 5.9X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). However, adsorption to soil is expected to attenuate volatilization(SRC). N-dodecyl mercaptan is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 8.53X10-3 mm Hg(4). Biodegradation data were not available(SRC, 2005).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1.1X10+4(SRC), determined from a structure estimation method(2), indicates that N-dodecyl mercaptan is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 5.9X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 4 hours and 6 days, respectively(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 77 days if adsorption is considered(5). According to a classification scheme(6), an estimated BCF of 360(SRC), from an estimated log Kow of 6.2(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is moderate (SRC). Biodegradation data were not available(SRC, 2005).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), N-dodecyl mercaptan, which has a vapor pressure of 8.53X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase N-dodecyl mercaptan is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 7 hours(SRC), calculated from its rate constant of 5.5X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). N-dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of N-dodecyl mercaptan with photochemically-produced hydroxyl radicals has been estimated as 5.5X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 7 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). A half-life of 100 days was reported for N-dodecyl mercaptan reaction with ozone(2). N-dodecyl mercaptan is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3). N-dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 360 was calculated for N-dodecyl mercaptan(SRC), using an estimated log Kow of 6.18(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC), provided the compound is not metabolized by the organism(SRC).
Using a structure estimation method based on molecular connectivity indices(1), the Koc of N-dodecyl mercaptan can be estimated to be 1.1X10+4(SRC). According to a classification scheme(2), this estimated Koc value suggests that N-dodecyl mercaptan is expected to be immobile in soil.

The Henry's Law constant for N-dodecyl mercaptan is estimated as 5.9X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that N-dodecyl mercaptan is expected to volatilize rapidly from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 4 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 6 days(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 77 days if adsorption is considered(3). N-dodecyl mercaptan's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC); however, the compound is reported as having extremely low volatility(4). N-dodecyl mercaptan is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 8.53X10-3 mm Hg(5).

SEDIMENT: N-dodecyl mercaptan was detected from sites adjacent to the 102nd St. Dump site, Bloody Run Creek, and Gill Creek hazardous waste disposal areas in Niagara Falls, NY at concentrations of 3 ppm, not detected (detection limit = 0.5 ppm in sediment), and not detected, respectively, sampled in June and November, 1979(1). The dumps are in the vicinity of Love Canal(1).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 92,230 workers (17,777 of these are female) are potentially exposed to N-dodecyl mercaptan in the US(1). Occupational exposure to N-dodecyl mercaptan may occur through inhalation and dermal contact with this compound at workplaces where N-dodecyl mercaptan is produced or used(SRC). The greatest potential for dermal and inhalation exposure to N-dodecyl mercaptan is expected at the packing station at the manufacturing site and to a lesser extent during activities at the consumer site(SRC).

Applications of N-dodecyl mercaptan
N-dodecyl mercaptan is used in the preparation of hydrophobic or mixed self-assembled monolayers. N-dodecyl mercaptan is also employed as a chain transfer agent for radical polymerization. Further, it is utilized as a polymerization inhibitor in polyurethane and neoprene adhesives, which finds application in the footwear industry. In addition to this, it acts as a protein regenerating agent used for the regeneration of native proteins from mercuribenzoate.

Solubility of N-dodecyl mercaptan
Immiscible with water.
Notes
Air and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, oxidizing agents, reducing agents and alkali metals.

n-Dodecyl mercaptan transfer constant in polymerization of methyl methacrylate
This paper investigates the effect of n-dodecyl mercaptan (n-DDM) as a chain transfer agent on the molecular weight of poly(methyl methacrylate). The transfer constant of n-Dodecyl mercaptan was calculated at different temperatures; the activation energy and frequency factor for an Arrhenius equation of transfer constant were then obtained.

Kinetics of the styrene emulsion polymerization using n‐dodecyl mercaptan as chain‐transfer agent
The kinetics of the styrene emulsion polymerization using n‐dodecyl mercaptan as chain‐transfer agent was studied. n‐dodecyl mercaptan was found that the chain‐transfer agent (CTA) had no effect on polymerization rate but substantially affected the molecular weight distribution (MWD). The efficiency of the CTA in reducing the MWD was lowered by the mass‐transfer limitations. The process variables affecting CTA mass transfer were investigated. A mathematical model for the process was developed. The outputs of the model include monomer conversion, particle diameter, number of polymer particles, and number‐average and weight‐average molecular weights. The model was validated by fitting the experimental data.

Polymerization of methyl methacrylate by 2‐pyrrolidinone and n‐dodecyl mercaptan
The bulk polymerization of methyl methacrylate initiated with 2‐pyrrolidinone and n‐dodecyl mercaptan (R‐SH) has been explored. This polymerization system showed “living” characteristics; for example, the molecular weight of the resulting polymers increased with reaction time by gel permeation chromatographic analysis. Also, the polymer was characterized by Fourier transform infrared spectroscopy, 1H NMR, and 13C NMR techniques. The polymer end with the iniferter structures was found. By the initial‐rate method, the polymerization rate depended on [2‐pyrrolidinone]1.0 and [R‐SH]0. Combining the structure analysis and the polymerization‐rate expression, a possible mechanism was proposed. n‐Dodecyl mercaptan served dual roles—as a catalyst at low conversion and as a chain‐transfer agent at high conversion. Finally, the thermal properties were studied, and the glass‐transition temperature and thermal‐degradation temperature were, respectively, 25 and 80–100 °C higher than that of the azobisisobutyronitrile system.

General description of N-dodecyl mercaptan
1-Dodecanethiol (DDT) is an alkyl thiol that forms a self-assembled monolayer (SAM) and can be used as an organic source of sulfur with balanced physio-chemical properties.[2]

Application of N-dodecyl mercaptan
N-dodecyl mercaptan (DDT) can be used as a source of sulfur for the synthesis CdS quantum dots (QDs) and lead sulfide nanoparticles (PbS) which find potential applications in energy efficient lighting, solar cells and as ammonium gas sensing agents. N-dodecyl mercaptan may be used to form a self-assembled monolayer (SAM) on copper surface as a corrosion resistant coating. [6]Functionalization with DDT may form SAMs on geranium (Ge) to improve the surface characteristics for futuristic applications in microelectronics.[7]
This molecule is used for the production of hydrophobic SAMs. N-dodecyl mercaptan can also be used in mixed SAMs to give a hydrophobic background and act as a spacer to move other functional groups or domains farther apart.

Polymers and Rubber Applications
Normal dodecyl mercaptan (n-dodecyl mercaptan, 1-dodecanethiol, lauryl mercaptan, NDDM, CAS # 112-55-0) is used as reactants in the synthesis of antioxidants, which minimize undesirable effects from processes such as the stabilization of tin.
Applications
Additives
Antioxidants
Lubricants
Polymers

n-Dodecyl mercaptan's production and use in pharmaceuticals, insecticides, nonionic detergents, synthetic rubber processing, and as a froth flotation agent for metal refining may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 8.53X10-3 mm Hg at 25 °C indicates n-Dodecyl mercaptan will exist solely as a vapor in the ambient atmosphere. Vapor-phase n-Dodecyl mercaptan will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 7 hours. n-Dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight. If released to soil, n-Dodecyl mercaptan is expected to be immobile based upon an estimated Koc of 1.1X10+4. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 5.9X10-2 atm-cu m/mole. However, adsorption to soil is expected to attenuate volatilization. Biodegradation data were not available. If released into water, n-Dodecyl mercaptan is expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 4 hours and 6 days, respectively. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 77 days if adsorption is considered. An estimated BCF of 360 suggests the potential for bioconcentration in aquatic organisms is moderate. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to n-Dodecyl mercaptan may occur through inhalation and dermal contact with this compound at workplaces where n-Dodecyl mercaptan is produced or used. The greatest potential for dermal and inhalation exposure to n-Dodecyl mercaptan is expected at the packing station at the manufacturing site and to a lesser extent during activities at the consumer site. 

n-Dodecyl mercaptan's production and use in pharmaceuticals, insecticides, nonionic detergents, synthetic rubber processing, and as a froth flotation agent for metal refining(1) may result in its release to the environment through various waste streams(SRC).
Based on a classification scheme(1), an estimated Koc value of 1.1X10+4(SRC), determined from a structure estimation method(2), indicates that n-Dodecyl mercaptan is expected to be immobile in soil(SRC). Volatilization of n-Dodecyl mercaptan from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 5.9X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(3). However, adsorption to soil is expected to attenuate volatilization(SRC). n-Dodecyl mercaptan is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 8.53X10-3 mm Hg(4). Biodegradation data were not available(SRC, 2005).

According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), n-Dodecyl mercaptan, which has a vapor pressure of 8.53X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase n-Dodecyl mercaptan is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 7 hours(SRC), calculated from its rate constant of 5.5X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). n-Dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).
The rate constant for the vapor-phase reaction of n-Dodecyl mercaptan with photochemically-produced hydroxyl radicals has been estimated as 5.5X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 7 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). A half-life of 100 days was reported for n-Dodecyl mercaptan reaction with ozone(2). n-Dodecyl mercaptan is not expected to undergo hydrolysis in the environment due to the lack of hydrolyzable functional groups(3). n-Dodecyl mercaptan does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

The Henry's Law constant for n-Dodecyl mercaptan is estimated as 5.9X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that n-Dodecyl mercaptan is expected to volatilize rapidly from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 4 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 6 days(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 77 days if adsorption is considered(3). n-Dodecyl mercaptan's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC); however, the compound is reported as having extremely low volatility(4). n-Dodecyl mercaptan is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 8.53X10-3 mm Hg(5).
NIOSH (NOES Survey 1981-1983) has statistically estimated that 92,230 workers (17,777 of these are female) are potentially exposed to n-Dodecyl mercaptan in the US(1). Occupational exposure to n-Dodecyl mercaptan may occur through inhalation and dermal contact with this compound at workplaces where n-Dodecyl mercaptan is produced or used(SRC). The greatest potential for dermal and inhalation exposure to n-Dodecyl mercaptan is expected at the packing station at the manufacturing site and to a lesser extent during activities at the consumer site(SRC).

N-Dodecyl Mercaptan is used in lubricant intermediates to produce additives as well as final components to improve lubricant performance in base oils and metal working fluids. Moreover Normal Dodecyl Mercaptan ( 1-dodecanethiol, lauryl mercaptan, NDDM) is used as reactants in the synthesis of antioxidants, which minimize undesirable effects from processes such as the stabilization of tin.

n-Dodecyl mercaptan transfer constant in polymerization of methyl methacrylate
This paper investigates the effect of n-dodecyl mercaptan (n-DDM) as a chain transfer agent on the molecular weight of poly(methyl methacrylate). The transfer constant of n-Dodecyl mercaptan was calculated at different temperatures; the activation energy and frequency factor for an Arrhenius equation of transfer constant were then obtained.

Kinetics of the styrene emulsion polymerization using n‐dodecyl mercaptan as chain‐transfer agent
The kinetics of the styrene emulsion polymerization using n‐dodecyl mercaptan as chain‐transfer agent was studied. n‐dodecyl mercaptan was found that the chain‐transfer agent (CTA) had no effect on polymerization rate but substantially affected the molecular weight distribution (MWD). The efficiency of the CTA in reducing the MWD was lowered by the mass‐transfer limitations. The process variables affecting CTA mass transfer were investigated. A mathematical model for the process was developed. The outputs of the model include monomer conversion, particle diameter, number of polymer particles, and number‐average and weight‐average molecular weights. The model was validated by fitting the experimental data.
N-Dodecyl mercaptan is not soluble in water, slightly soluble in light alcohols and soluble in styrene and most organic solvents.
N-Dodecyl Mercaptan is used in lubricant intermediate to produce additives and final components. At the same time is it also used for polymers and rubber applications.
N-Dodecyl Mercaptan is used in lubricant intermediates to produce additives as well as final components to improve lubricant performance in base oils and metal working fluids. Moreover Normal Dodecyl Mercaptan ( 1-dodecanethiol, lauryl mercaptan, NDDM) is used as reactants in the synthesis of antioxidants, which minimize undesirable effects from processes such as the stabilization of tin.