POLYSORBATE 80 (E433)

Polysorbate 80 (E433) is a nonionic surfactant and emulsifier widely used in food, pharmaceuticals, cosmetics, and industrial formulations.
Polysorbate 80 (E433) stabilizes oil-in-water emulsions and enhances solubilization of lipophilic active ingredients.
Polysorbate 80 (E433) improves texture, consistency, and dispersibility in diverse aqueous systems.
Polysorbate 80 (E433) is derived from sorbitol and oleic acid and is suitable for applications requiring mild, non-irritating emulsification.

CAS Number: 9005-65-6
EC Number: 500-019-9
Molecular Formula: C64H124O26 (approx.)
Molecular Weight: ~1310 g/mol (average polymer distribution)

Synonyms: Tween 80, Polyoxyethylene (20) sorbitan monooleate, PEG-80 sorbitan oleate, Sorbitan monooleate ethoxylated, Food emulsifier E433, Polysorbate-80, Surfactant Tween 80, Cosmetic emulsifier 80, Solubilizer polysorbate, Nonionic oleate emulsifier, Polysorbate 80 (E433), Polysorbate 80, Tween 80, E433, PEG-80 Sorbitan Oleate, Polyoxyethylene (20) Sorbitan Monooleate, Polyoxyethylene Sorbitan Oleate, Sorbitan Monooleate Ethoxylated, Sorbitan Monooleate Polyoxyethylene, Polysorbate-80, Tween-80 Emulsifier, Tween-80 Surfactant, Tween 80 Food Grade, Tween 80 Pharmaceutical Grade, Tween 80 Cosmetic Grade, Tween 80 Laboratory Grade, Tween 80 Industrial Grade, Tween 80 Technical Grade, Polysorbate 80 Emulsifier, Polysorbate 80 Solubilizer, Polysorbate 80 Surfactant, Polysorbate 80 Dispersant, Polysorbate 80 Wetting Agent, Polysorbate 80 Solubilizing Agent, Polysorbate 80 Emulsifying Agent, Polysorbate 80 Stabilizer, Polysorbate 80 Food Emulsifier, Polysorbate 80 Food Additive, Polysorbate 80 Solvent, Polysorbate 80 Pharmaceutical Excipient, Polysorbate 80 Cosmetic Ingredient, Polysorbate 80 Personal Care Ingredient, Polysorbate 80 Oral Care Ingredient, Polysorbate 80 Injectable Excipient, Polysorbate 80 Vaccine Stabilizer, Polysorbate 80 Biopharmaceutical Excipient, Polysorbate 80 Biotech Grade, Polysorbate 80 High Purity

APPLICATIONS

Polysorbate 80 (E433) is used in food emulsions such as dressings and sauces.
Polysorbate 80 (E433) improves creaminess and stability in dairy products and beverages.
Polysorbate 80 (E433) enhances dispersion of flavors and colorants in food systems.

Polysorbate 80 (E433) is used in ice cream to improve overrun and texture.
Polysorbate 80 (E433) prevents ice crystal formation and enhances smoothness.
Polysorbate 80 (E433) stabilizes fat-air interfaces in frozen desserts.

Polysorbate 80 (E433) is applied in bakery mixes and whipped toppings.
Polysorbate 80 (E433) improves batter aeration and shelf stability.
Polysorbate 80 (E433) enhances foam structure and volume.

Polysorbate 80 (E433) is used in pharmaceutical formulations as a solubilizer.
Polysorbate 80 (E433) improves bioavailability of poorly soluble drugs.
Polysorbate 80 (E433) stabilizes injectable and oral suspensions.

Polysorbate 80 (E433) is used in vaccines as an emulsifier and stabilizer.
Polysorbate 80 (E433) supports antigen dispersion and formulation stability.
Polysorbate 80 (E433) improves syringeability and uniformity.

Polysorbate 80 (E433) is used in cosmetics such as lotions, creams, and serums.
Polysorbate 80 (E433) solubilizes essential oils and fragrances in aqueous bases.
Polysorbate 80 (E433) enhances spreadability and sensory profile.

Polysorbate 80 (E433) is used in shampoos and cleansers to improve surfactant mildness.
Polysorbate 80 (E433) reduces irritation and enhances foam performance.
Polysorbate 80 (E433) supports oil-cleansing formulations for sensitive skin.

Polysorbate 80 (E433) is used in oral and veterinary products.
Polysorbate 80 (E433) stabilizes suspensions and promotes uniform dosing.
Polysorbate 80 (E433) improves solubility of hydrophobic active ingredients.

Polysorbate 80 (E433) is used in biotechnology and cell-culture media.
Polysorbate 80 (E433) protects proteins from aggregation and denaturation.
Polysorbate 80 (E433) enhances recombinant protein stability.

Polysorbate 80 (E433) is used in industrial cleaners and defoamers.
Polysorbate 80 (E433) improves emulsification of oils and contaminants.
Polysorbate 80 (E433) maintains stable aqueous cleaning systems.

Polysorbate 80 (E433) is used as a nonionic emulsifier in food products.
Polysorbate 80 (E433) stabilizes oil-in-water emulsions in processed foods.
Polysorbate 80 (E433) improves mouthfeel and product stability in beverages and sauces.

Polysorbate 80 (E433) is applied in ice cream formulations.
Polysorbate 80 (E433) enhances aeration and smooth texture in frozen desserts.
Polysorbate 80 (E433) reduces ice crystal formation during storage.

Polysorbate 80 (E433) is used in baked goods and cake mixes.
Polysorbate 80 (E433) improves batter aeration and crumb structure.
Polysorbate 80 (E433) extends shelf life by maintaining moisture distribution.

Polysorbate 80 (E433) is applied in confectionery and chocolate coatings.
Polysorbate 80 (E433) improves viscosity control in chocolate systems.
Polysorbate 80 (E433) enhances gloss and flow during enrobing.

Polysorbate 80 (E433) is used in dairy and flavored milk drinks.
Polysorbate 80 (E433) helps disperse flavors and fats evenly.
Polysorbate 80 (E433) prevents creaming and phase separation.

Polysorbate 80 (E433) is incorporated in salad dressings and mayonnaise.
Polysorbate 80 (E433) stabilizes vinegar-oil systems and prevents separation.
Polysorbate 80 (E433) enhances smooth texture and uniform viscosity.

Polysorbate 80 (E433) is used in pharmaceutical formulations.
Polysorbate 80 (E433) solubilizes poorly soluble active ingredients.
Polysorbate 80 (E433) stabilizes injectable and vaccine emulsions.

Polysorbate 80 (E433) is applied in eye drops and ophthalmic solutions.
Polysorbate 80 (E433) improves drug dispersion and tear film compatibility.
Polysorbate 80 (E433) enhances stability and clarity in sterile solutions.

Polysorbate 80 (E433) is used in parenteral nutrition emulsions.
Polysorbate 80 (E433) enables emulsification of lipid-based nutrients.
Polysorbate 80 (E433) supports physiologically stable fat emulsions.

Polysorbate 80 (E433) is incorporated in cosmetic creams and lotions.
Polysorbate 80 (E433) stabilizes emulsions and enhances consistency.
Polysorbate 80 (E433) improves spreadability and texture in skin care products.

Polysorbate 80 (E433) is used in hair conditioners and serums.
Polysorbate 80 (E433) helps solubilize oils and silicones.
Polysorbate 80 (E433) improves softness and shine in hair formulations.

Polysorbate 80 (E433) is used in essential oil solubilization.
Polysorbate 80 (E433) disperses fragrance oils in aqueous systems.
Polysorbate 80 (E433) prevents cloudiness in scented sprays and toners.

Polysorbate 80 (E433) is applied in nutraceutical suspensions.
Polysorbate 80 (E433) enhances dispersion of botanical extracts and vitamins.
Polysorbate 80 (E433) maintains clarity and uniformity over shelf life.

Polysorbate 80 (E433) is used in biotechnology and protein solutions.
Polysorbate 80 (E433) protects proteins from denaturation and surface adsorption.
Polysorbate 80 (E433) stabilizes biologics during freeze-thaw cycles.

DESCRIPTION

Polysorbate 80 (E433) is a nonionic surfactant and emulsifier derived from sorbitol and oleic acid.
Polysorbate 80 (E433) is commonly used in food, pharmaceutical, and personal care formulations.
Polysorbate 80 (E433) helps solubilize hydrophobic ingredients in aqueous systems.

Polysorbate 80 (E433) has the CAS number 9005-65-6.
Polysorbate 80 (E433) has the chemical formula C64H124O26.
Polysorbate 80 (E433) is also known as Polyoxyethylene (20) Sorbitan Monooleate.

Polysorbate 80 (E433) appears as a yellow to amber viscous liquid.
Polysorbate 80 (E433) is soluble in water, ethanol, and vegetable oils.
Polysorbate 80 (E433) has a mild fatty odor and neutral taste when used in food applications.

Polysorbate 80 (E433) has a high hydrophilic-lipophilic balance (HLB ≈ 15).
Polysorbate 80 (E433) provides excellent stability in acidic and neutral pH systems.
Polysorbate 80 (E433) is heat-stable and suitable for pasteurization and sterilization.

Polysorbate 80 (E433) is widely recognized as safe for regulated food and pharma use.
Polysorbate 80 (E433) is compatible with proteins, oils, and bioactive compounds.
Polysorbate 80 (E433) should be stored tightly sealed away from heat, light, and oxidizing agents to maintain quality.

Polysorbate 80 (E433) is a viscous, yellow-brown to amber liquid.
Polysorbate 80 (E433) exhibits excellent solubilizing and emulsifying performance.
Polysorbate 80 (E433) disperses hydrophobic actives into aqueous media.

Polysorbate 80 (E433) is produced by ethoxylation of sorbitan monooleate.
Polysorbate 80 (E433) features polyoxyethylene groups for hydrophilicity.
Polysorbate 80 (E433) is nonionic and compatible with ionic and nonionic surfactants.

Polysorbate 80 (E433) is biodegradable and safe for regulated food and pharmaceutical use.
Polysorbate 80 (E433) remains stable across wide pH and temperature ranges.
Polysorbate 80 (E433) supports long-term formulation stability in emulsions and solubilized systems.

Polysorbate 80 (E433) does not significantly alter taste or color in foods.
Polysorbate 80 (E433) provides mild emulsification without greasy feel in cosmetics.

PROPERTIES

Appearance: Viscous amber-yellow liquid
Odor: Mild, slightly oily odor
Solubility: Completely miscible with water and alcohols
HLB Value: ~15
Density: ~1.07 g/cm³
Viscosity: High viscosity liquid
Boiling Point: Decomposes before boiling
pH: Neutral to slightly acidic
Stability: Stable under normal storage and pH conditions
Storage Temperature: Store at 15–30°C, protect from moisture and contamination

FIRST AID

Inhalation:
Move to fresh air if aerosol or vapor is inhaled.
Seek medical attention if symptoms develop.

Skin Contact:
Wash skin with soap and water.
Discontinue use if irritation occurs.

Eye Contact:
Rinse carefully with water for 15 minutes.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth and drink water.
Seek medical attention if discomfort develops.

Note to Physicians:
Treat symptomatically and provide supportive care.

HANDLING AND STORAGE

Handling:
Wear gloves and safety glasses when handling in concentrated form.
Avoid generating mists during processing.

Ventilation:
Use adequate ventilation in industrial environments.

Avoidance:
Avoid strong oxidizing agents.

Spill and Leak Procedures:
Wipe or absorb with inert material.
Wash area with water and mild detergent.

Storage:
Store tightly sealed in a cool, dry place.
Protect from heat and direct sunlight.

Handling Cautions:
Use sanitary equipment for food and pharmaceutical applications.
Avoid contamination during transfer and storage.