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Provichem 0333 was used in the synthesis of 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane.
Provichem 0333 was also used in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end.
Provichem 0333 is essential building blocks for ethoxyethanol derivatives such as Quetiapine and Cetirizine.
CAS: 5197-62-6
MF: C6H13ClO3
MW: 168.62
EINECS: 225-984-0
Provichem 0333 is a coumarin derivative that is used as an additive in the fabrication of polyurethane.
Magnetic resonance spectroscopy has shown that CETOI can be used as a probe to study amide groups by Provichem 0333's ability to form hydrogen bonds with amide groups.
Provichem 0333 can also be used in regenerative medicine and cyclic peptides.
Azobenzene monomers have been shown to inhibit viral replication, including influenza virus, through the formation of covalent bonds with phosphate groups on dsDNA.
Provichem 0333 is a chemical compound that is used in a variety of scientific and industrial applications.
Provichem 0333 is a colorless, volatile liquid with a sweet smell and a low boiling point.
Provichem 0333 is a derivative of ethylene glycol and is often used as a solvent in organic synthesis.
Provichem 0333 is a versatile compound that is used in a variety of scientific and industrial applications, including pharmaceuticals, polymers production, and as a reagent in organic synthesis.
Provichem 0333 Chemical Properties
Boiling point: 117-120 °C5 mm Hg(lit.)
Density: 1.16 g/mL at 25 °C(lit.)
Refractive index: n20/D 1.458(lit.)
Fp: 225 °F
Storage temp.: 2-8°C
Solubility: Chloroform (Slightly)
pka: 14.36±0.10(Predicted)
Form: Liquid
Color: Clear slightly yellow
BRN: 1739194
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: KECMLGZOQMJIBM-UHFFFAOYSA-N
CAS DataBase Reference: 5197-62-6(CAS DataBase Reference)
Uses
Provichem 0333 is used in the preparation of ethylene glycol based amino acids.
Provichem 0333 is also used in the preparation of polymers for direct and amplified DNA detection.
Provichem 0333 has a wide range of scientific research applications.
Provichem 0333 is commonly used as a reagent in organic synthesis, as a solvent for chemical reactions, and as a reactant in the production of polymers.
Provichem 0333 is also used in pharmaceutical research as a solvent for drug delivery systems, and as a reactant in the synthesis of active pharmaceutical ingredients (APIs).
Synthesis Method
Provichem 0333 can be synthesized by the reaction of ethylene glycol with chloroethanol in the presence of a catalyst.
The reaction is typically carried out in an inert atmosphere such as nitrogen or argon.
The reaction is exothermic and proceeds smoothly at room temperature.
The reaction can be monitored by gas chromatography and Provichem 0333 can be purified by distillation.
Mechanism of Action
Provichem 0333 acts as a solvent in organic synthesis and as a reactant in the production of polymers.
Provichem 0333 is also used as a reactant in the synthesis of active pharmaceutical ingredients (APIs).
Provichem 0333 is a nucleophilic reagent and can react with electrophiles to form covalent bonds.
Provichem 0333 can also act as a Lewis base and can coordinate with Lewis acids to form complexes.
Biochemical and Physiological Effects
Provichem 0333 is generally regarded as non-toxic and does not exhibit any significant biochemical or physiological effects.
However, Provichem 0333 is considered to be an irritant and should be handled with care.
Inhalation of Provichem 0333 vapors can cause irritation of the eyes, nose, and throat.
Synonyms
5197-62-6
2-(2-(2-Chloroethoxy)ethoxy)ethanol
2-[2-(2-Chloroethoxy)ethoxy]ethanol
Ethanol, 2-[2-(2-chloroethoxy)ethoxy]-
Triethylene glycol monochlorohydrin
Triethylene glycol monochloride
2-[2-(2-chloroethoxy)ethoxy]ethan-1-ol
MFCD00002874
Ethanol, 2-(2-(2-chloroethoxy)ethoxy)-
2-(2-(2-chloro-ethoxy)ethoxy)ethanol
2-(2-(2-chloroethoxy)ethoxy)-ethanol
2-[2-(2-chloro-ethoxy)ethoxy]ethanol
2-[2-(2-chloroethoxy)ethoxy]-ethanol
NSC2636
NSC 2636
EINECS 225-984-0
AI3-02506
Cl(CH2CH2O)3H
Cl(C2H4O)3H
SCHEMBL315062
DTXSID30199936
8-Chloro-3,6-dioxaoctane-1-ol
2-(2-(chloroethoxy)ethoxy)ethanol
NSC-2636
ZINC1641047
2-[2-(2-cloroethoxy)ethoxy]ethanol
AKOS006220767
2-(2-(2-chloroethoxyl)ethoxy)ethanol
CS-W016036
FS-4420
2-(2-(-2-chloroethoxy)ethoxy)ethanol
2-[2-(2-chloroethoxy)-ethoxy]ethanol
2-[2-(2-chloroethoxy)-ethoxy]-ethanol
SY051536
2-[2-(2-Chloro-ethoxy)-ethoxy]-ethanol
DB-104119
2-[2-(2-Chloroethoxy)ethoxy]ethanol, 96%
C1416
FT-0704223
EN300-134537
H11263
A871109
