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RED 2G

CAS NO:3734-67-6
EC NO:223-098-9

Red 2G is a synthetic red azo dye. 
Red 2G is soluble in water and slightly soluble in glycerol. 
Red 2G usually comes as a disodium salt of 8-acetamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulfonate.

Uses
Food dye
In the European Union, Red 2G was used as a food dye (E number E128). However, it was only permitted for use in breakfast sausages with a minimum cereal content of 6% and burger meat with a minimum vegetable and/or cereal content of 4%.

Red 2G is also banned in Australia, Canada, Japan, Norway, and Malaysia. 
It was banned in Israel in July 2007[citation needed].

Red 2G is relatively insensitive to the bleaching effect of sulfur dioxide (E220) and sodium metabisulfite (E223). In the intestines, Red 2G can be converted to the toxic compound aniline,so there are concerns Red 2G may ultimately interfere with blood haemoglobin, as well as cause cancer.

Inks
Red 2G is also used as a dye for coatings, inks, paper, crepe paper, and fine tissue.

Histology
Red 2G can be also used for staining in histology, though rarely, e.g. as a component of Masson's trichrome.

Properties
Chemical formula    C18H13N3O8S2
Molar mass    463.44 g·mol−1
Solubility in water    18 g/100 mL (20 °C)
Solubility    1 g/ 100 mL glycerol
Negligible in ethanol

General description
Red 2G is a compound, which belongs to the azo family of dyes, generally used in textile industry.
Red 2G can mainly find applications in non-linear optical studies.
Red 2G (E-128) is used for the quality control in food products. 
Red 2G belongs to the class of water-soluble synthetically prepared, food color additives, reportedly banned by the European and United states union. These synthetic food colors are commonly used to compensate for the loss of natural colors of food, destroyed during processing and storage. They also maintain and improve the color appearance in food products. 
Red 2G is a mono azo dye, reported to cause increased iron deposition in the human kidney. 
Red 2G finds applications as a color additive in burger meat and sausages.

Application
Red 2G may be used as an analytical reference standard for the quantification of the analyte in:
Drinks and candies using reversed-phase high-performance liquid chromatography with photodiode array detection (RP-HPLC-PDA).
Food products, beverages and water-soluble foods using reversed-phase high-performance liquid chromatography with diode array detection (RP-HPLC-DAD).

Red 2G (also known as CI Food Red 10; INS No. 128) is a synthetic dye commercially available as the sodium salt of the dye (water-soluble) or the aluminium lake (water-insoluble).
Red 2G imparts light red colour, producing cherry to blood-red shades in foods. 
Red 2G has excellent stability to heat, light, acids and sulphur dioxide.

Red 2G, food additive and synthetic dye find its suitability in water as well as ethanol and applies to paper, crepe paper, coatings, ink, fine tissue and staining in histology. Commonly used in food, pharma and cosmetic industries in black and granular form.

E-128 Red 2G is a red food colorant. Human health should be included in the content of participation in food. The additive should not bring new products by reacting with a fresh, packaged material of a part of the food, and should not show it as superior or superior to a product. Many processed foods such as ice cream, batter yoghurt, pudding, raw-cooked meat products, sausage, salami sausage are allowed in predictable rates in Turkish Food Codecs. 
E-128 Red 2G analysis is performed to detect that it is not used in products.

Red 2G Food Color or Red 2G Food Additive or Red 2G Food Dye finds application as synthetic red azo dye and finds solubility in water as well as slight solubility in ethanol. The dye normally comes as disodium salt of 8-acetamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulphonate and finds application as dye for paper, crepe paper, coatings, inks, fine tissue.

Further, it can also be used for staining in histology. Made available in black granular and powder form, its part of commonly used dyes in the food, pharmaceutical and cosmetic industries and comes with properties of water-insoluble matter, percent by mass (maximum) of 00.20; Dye intermediates, percent by mass (max) of 00.50 and subsidiary dyes, percent by mass (max) of 02.00.

Red 2G, Acid Red 1, Food Red 10, Amidonaphthol red G, azogeranine, azophloxine, azofloxin, or C.I. 18050, is a synthetic red azo dye. 
Red 2G is soluble in water and slightly soluble in ethanol. 
Red 2G usually comes as a disodium salt of 8-actamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulphonate.

Its CAS number is [3734-67-6] and its SMILES structure is CC(=O)Nc1cc(OS([O-])=O)cc2cc(OS([O-])=O)c(/N=N/c3ccccc3)c(O)c12.

Uses
In the European Union, Red 2G is used as a food dye (E number E128). However, it is only permitted for use in breakfast sausages with a minimum cereal content of 6% and burger meat with a minimum vegetable and/or cereal content of 4%. 

Red 2G is banned in Australia, Austria, Canada, Japan, Norway, Sweden, Malaysia[5] and the United States.
Red 2G was banned in Ireland, Israel and Greece in July 2007. .

Red 2G is relatively insensitive to the bleaching effect of sulfur dioxide (E220) and sodium metabisulfite (E223). In the intestines, Red 2G can be converted to the toxic compound aniline , so there are concerns Red 2G may ultimately interfere with blood haemoglobin, as well as cause cancer.

Red 2G is also used as a dye for coatings, inks, paper, crepe paper, and fine tissue.

Red 2G can be also used for staining in histology, though rarely, e.g. as a component of Masson's trichrome.

CI 18050. Red 2G by Neelikon Food Colours & Chemicals acts as an organic coloring pigment. 
Red 2G offers high quality, extremely low impurity and consistent tone. Moreover, it is non-GMO derived. 
Red 2G finds application in formulating toiletries and personal care products like shampoos, conditioners, bath soaps, hair gels, toothpastes (transparent, opaque, stripes), lotions, deodorants, liquid soaps, hand washes, hair oil, after-shave and skin creams. Complies with US FDA, Halal, Kosher, ISI and REACH.

Red 2G is a useful stain with color index of 18050.
Red 2G is a synthetic red azo dye used as food additive. Studies have shown that Red 2G is converted to toxic compound aniline and may ultimately interfere with blood haemoglobin.

Red 2G, tech. is a synthetic red azo dye used as food additive. Studies have shown that Red 2G is converted to toxic compound aniline and may ultimately interfere with blood haemoglobin. Dyes and metabolites, Environmental Testing.

About this substance
Helpful information
Red 2G is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.

Red 2G is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses
Red 2G is used in the following products: biocides (e.g. disinfectants, pest control products), plant protection products, air care products, fertilisers, inks and toners, laboratory chemicals, perfumes and fragrances, polishes and waxes, washing & cleaning products and cosmetics and personal care products.
Other release to the environment of Red 2G is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Article service life
Release to the environment of Red 2G can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Red 2G is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
Red 2G can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

Widespread uses by professional workers
Red 2G is used in the following products: textile treatment products and dyes, air care products, biocides (e.g. disinfectants, pest control products), fertilisers, inks and toners, laboratory chemicals, plant protection products, perfumes and fragrances, polishes and waxes, washing & cleaning products and cosmetics and personal care products.
Red 2G is used for the manufacture of: textile, leather or fur.
Other release to the environment of Red 2G is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing
Red 2G is used in the following products: inks and toners, leather treatment products, paper chemicals and dyes, textile treatment products and dyes, air care products, biocides (e.g. disinfectants, pest control products), fertilisers, laboratory chemicals, plant protection products, perfumes and fragrances, polishes and waxes, washing & cleaning products and cosmetics and personal care products.
Release to the environment of Red 2G can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites
Red 2G is used in the following products: paper chemicals and dyes, textile treatment products and dyes, inks and toners, polymers and leather treatment products.
Red 2G is used in the following areas: printing and recorded media reproduction.
Red 2G is used for the manufacture of: textile, leather or fur, pulp, paper and paper products, wood and wood products and plastic products.
Release to the environment of Red 2G can occur from industrial use: in the production of articles.

Manufacture
Release to the environment of Red 2G can occur from industrial use: manufacturing of the substance.

Red 2G is an organic sodium salt that is the disodium salt of 5-acetamido-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonic acid. 
Red 2G has a role as a histological dye. 
Red 2G contains a 5-acetamido-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonate.

Red 2G, also known as acid red 1 (AR1), is a member of synthetic red azo dye family.

Red 2G, also known as acid red 1 (AR 1), is a member of synthetic red azo dye family.
Red 2G is an organic dye with good photo-thermal stability, dissolvability and easy preparation feature. In addition, it also has noticeable third order nonlinearity and good optical power limiting properties. 
Red 2G has been used as a real acid counterstain in light and fluorescence microscopy. 
Red 2G also facilitates the determination of proteins and peptides. 
Red 2G has been used as a dye in Von Kossa staining and nonlinear optical studies. 
Red 2G is also used in photocatalytic tests.

Red 2G is a synthetic red azo dye. 
Red 2G is soluble in water and slightly soluble in glycerol. 
Red 2G usually comes as a disodium salt of 8-acetamido-1-hydroxy-2-phenylazonaphthalene-3,6 disulfonate.


IUPAC names
(3E)-5-acetamido-4-oxo-3-(phenylhydrazinylidene)naphthalene-2,7-disulfonic acid
5-acetamido-4-oxo-3-(phenylhydrazinylidene)naphthalene-2,7-disulfonic acid
C.I. Acid Red 1
disodium (3Z)-5-acetamido-4-oxo-3-(phenylhydrazinylidene)naphthalene-2,7-disulfonate
disodium 5-acetamido-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonate
disodium 5-acetamido-4-hydroxy-3-[(E)-2-phenyldiazen-1-yl]naphthalene-2,7-disulfonate
disodium 5-acetamido-4-oxo-3-(phenylhydrazinylidene)naphthalene-2,7-disulfonate
disodium 5-acetamido-4-oxo-3-(phenylhydraznylidene)naphthalene-2,7-disulphonate
Disodium 5-acetylamino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate
disodium 5-acetylamino-4-hydroxy-3-(phenylazo)naphthalene-2,7-disulphonate
Red 2G
sodium (E)-5-acetamido-4-hydroxy-3-(phenyldiazenyl)naphthalene-2,7-disulfonate

SYNONYMS:
(3Z)-5-Acétamido-4-oxo-3-(phénylhydrazono)-3,4-dihydro-2,7-naphtalènedisulfonate de disodium [French] [ACD/IUPAC Name]
2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-3,4-dihydro-4-oxo-3-(2-phenylhydrazinylidene)-, sodium salt, (3Z)- (1:2) [ACD/Index Name]
Dinatrium-(3Z)-5-acetamido-4-oxo-3-(phenylhydrazono)-3,4-dihydro-2,7-naphthalindisulfonat [German] [ACD/IUPAC Name]
Disodium (3Z)-5-acetamido-4-oxo-3-(phenylhydrazono)-3,4-dihydro-2,7-naphthalenedisulfonate [ACD/IUPAC Name]
Red 2G
1379 Red
2,7-Naphthalenedisulfonic acid, 5-(acetylamino)-4-hydroxy-3-(phenylazo)-, disodium salt
3734-67-6 [RN]
97502-49-3 [RN]
Acetyl Red G
Acetyl Red J
Acetyl Rose 2GL
Acid Bright Red
Acid Brilliant Red
Acid Fast Red 3G
Acid Fast Red EGG
Acid Leather Red KG
Acid Naftol Red G
Acid Phloxine GA
Acid Red 1
Acid Red 2G
Acid Red GA
Acid Rose 2GL


 

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