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SODIUM BENZOATE

Sodium benzoate is a water-soluble preservative that helps inhibit yeasts, molds, and certain bacteria in acidic formulations.
Sodium benzoate is widely used in beverages, sauces, dressings, and pickled products to support shelf life and product stability.
Known as E211 in food applications, Sodium benzoate's effectiveness depends strongly on pH, with greater antimicrobial activity under acidic conditions.

CAS Number: 532-32-1
EC Number: 208-534-8
Molecular Formula: C7H5NaO2
Molecular Weight: 144.10317

Synonyms: Antimol, Benzoic acid, sodium salt, Benzoic acid sodium salt, Benzoate sodium, Benzoate of soda, Benzoate, sodium, sodium;benzoate, Sodiumbenzoate, Natrium benzoicum, FEMA No. 3025, Fuminaru, Benzoan sodny, Caswell No. 746, Microcare sb, PUROX S, FEMA Number 3025, Benzoan sodny [Czech], CCRIS 3921, HSDB 696, Benzoesaeure (na-salz), UNII-OJ245FE5EU, EINECS 208-534-8, OJ245FE5EU, benzoic acid sodium, EPA Pesticide Chemical Code 009103, INS NO.211, DTXSID1020140, E211, AI3-07835, Benzoesaeure (na-salz) [German], INS-211, DTXCID90140, Sodium benzoate [USAN:JAN], E-211, CHEBI:113455, Sodium benzoate [USAN:JAN:NF], EC 208-534-8, AMMONUL COMPONENT Sodium benzoate, UCEPHAN COMPONENT Sodium benzoate, Sodium benzoate COMPONENT OF AMMONUL, Sodium benzoate COMPONENT OF UCEPHAN, Sodium benzoic acid, Sodium benzoate (II), Sodium benzoate [II], Sodium benzoate (MART.), Sodium benzoate [MART.], Sodium benzoate (EP MONOGRAPH), Sodium benzoate [EP MONOGRAPH], C7H5NaO2, MFCD00012463, BzONa, monoSodium benzoate, Sodium benzoate USP, Sodium benzoate,(S), Sodium benzoate (TN), SCHEMBL823, CHEMBL1356, Sodium benzoate [MI], Sodium benzoate (JP17/NF), Sodium benzoate [FCC], Sodium benzoate [JAN], C7-H6-O2.Na, Sodium benzoate [FHFI], Sodium benzoate [HSDB], Sodium benzoate [INCI], Sodium benzoate [USAN], Sodium benzoate [VANDF], Sodium benzoate [USP-RS], Sodium benzoate [WHO-DD], Sodium benzoate (Fragrance Grade), Benzoic acid, sodium salt (1:1), HY-Y1316, Tox21_300125, Sodium benzoate [ORANGE BOOK], AKOS003053000, AKOS015890021, CCG-266169, LS-2390, NCGC00254072-01, CAS-532-32-1, CS-0017788, E 211, FT-0645126, S0593, D02277, A829462, Q423971, J-519752.

Sodium benzoate is the sodium salt of benzoic acid, widely used as a preservative in food, beverages, and other formulated products.
Sodium benzoate typically appears as a white crystalline powder or granules and dissolves readily in water.

Sodium benzoate's antimicrobial activity helps inhibit yeasts, molds, and certain bacteria, supporting product stability and shelf life.
Sodium benzoate works most effectively in acidic formulations, where a greater proportion is converted to undissociated benzoic acid.

Common applications include acidic beverages, sauces, pickled products, and fruit preparations.
Sodium benzoate's water solubility makes it convenient to incorporate into aqueous formulations.
In food applications, Sodium benzoate is identified as E211 or INS 211. 

Sodium benzoate is a common food preservative and additive that is widely used in the food and beverage industry. 
Sodium benzoate is the sodium salt of benzoic acid and has the chemical formula C7H5NaO2. 

Sodium benzoate is a white, odorless, and crystalline powder that is highly soluble in water.
One of the primary reasons for using Sodium benzoate as a preservative is its ability to inhibit the growth of bacteria, yeast, and fungi. 
Sodium benzoate is particularly effective in acidic conditions, which makes it suitable for use in acidic foods and beverages such as soft drinks, fruit juices, pickles, and condiments. 

Sodium benzoate works by disrupting the metabolic processes of microorganisms, thus preventing their growth and spoilage of food products.
Sodium benzoate is important to note that Sodium benzoate is considered safe for consumption when used within the approved limits set by regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). 

Some individuals may be sensitive or allergic to Sodium benzoate, and in rare cases, Sodium benzoate can cause adverse reactions or exacerbate certain health conditions.
Sodium benzoate is always recommended to read food labels and consult with healthcare professionals if you have any concerns.

Sodium benzoate is the sodium salt form of benzoic acid, and is synthesized by reacting benzoic acid with sodium hydroxide. 
While Sodium benzoate must be manufactured, benzoic acid is found naturally in certain foods such as apples, prunes, plums, greengages, cloves and certain berries.

Sodium benzoate is a sodium salt of benzoic acid, that is freely soluble in water compared to benzoic acid. 
Sodium benzoate is generally used as an antimicrobial preservative in cosmetics, food, and pharmaceuticals.

Sodium benzoate also can be used for carbonated beverages, concentrated juice, margarine, chewing gum base, jam, jelly, soy sauce, etc. Human acceptable daily intake (ADI) < 5 mg/kg body weight (take benzoic acid as calculation basis).
Sodium benzoate has big lipophilicity, and it is easy to penetrate cell membrane into the cells, interfere in permeability of cell membrane, and inhibit cell membrane’s absorption of amino acids; cause Ionization acidification of alkaline storage in the cell when entering into, inhibit activity of respiratory enzymes, and stop condensation reaction of acetyl coenzyme A, and thereby achieve the purpose of food  antiseptic.

Sodium benzoate is commonly produced by the neutralization of sodium hydroxide (NaOH) with benzoic acid (C6H5COOH), which is itself produced commercially by partial oxidation of toluene with oxygen.
Sodium benzoate is a widely used food preservative, with an E number of E211. 

Sodium benzoate is used as an antifungal preservative in cosmetics and in food under the name E211. 
Sodium benzoate is therefore very effective against fungi, yeasts and bacteria. 

Sodium benzoate is made quite easily with soda, water and benzoic acid. 
Sodium benzoate is found naturally in some fruits such as plums, prunes or apples.

Sodium benzoate is an organic alcohol found in many fruits and teas. 
Sodium benzoate has a hydroxyl group (-OH), while the related compound, Benzoic Acid has a carboxyl group (-COOH). 

Sodium benzoate, Calcium Benzoate and Potassium Benzoate are salts of Benzoic Acid.
Sodium benzoate is an ester of Benzyl Alcohol and Benzoic Acid.

Sodium benzoate, also known as Benzoic acid sodium salt , can be made by chemically by reacting sodium hydroxide with Benzoic acid. 
Sodium benzoate is odorless or with a slight smell of Benzoin, and tastes sweet astringency. 

Stable in air Sodium benzoate can absorb moisture in open air as a preservative Sodium benzoate is bacteriostatic and fungistatic under acidic conditions. 
Sodium benzoate as a food additive, Sodium benzoate has the E number E211.

Since Sodium benzoate contains a natural ingredient, Sodium benzoate is probably safe, right? After all, the US Food and Drug Administration (FDA) and the Canadian Health Protection Branch have pronounced this chemical preservative to be acceptable when consumed in low amounts.
Sodium benzoate is a preservative added to some sodas, packaged foods, and personal care products to prolong shelf life.

Sodium benzoate is best known as a preservative used in processed foods and beverages to extend shelf life, though it has several other uses.
Sodium benzoate is a common food preservative and a mold inhibitor. 

Applications of Sodium Benzoate:
Sodium benzoate is used as a preservative in acidic foods and beverages, including soft drinks, fruit preparations, sauces, dressings, and pickled products.
Sodium benzoate helps control yeasts, molds, and certain bacteria, supporting shelf life and product stability.

Sodium benzoate is also incorporated into pharmaceutical preparations, cosmetics, and personal care products to help protect suitable formulations against microbial spoilage.
Sodium benzoate's effectiveness depends on formulation pH and is greatest under acidic conditions.

Sodium benzoate is used in the fireworks as a fuel in whistle mix. 
Sodium benzoate is also used in the preparation of toothpaste and mouthwashes.

Sodium benzoate finds application in most of the acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments.
Sodium benzoate is produced by the neutralization of benzoic acid with sodium hydroxide.

Sodium benzoate also has applications beyond the food industry. 
Sodium benzoate is used in various personal care products, such as cosmetics, shampoos, and lotions, to inhibit the growth of bacteria and fungi. 

Sodium benzoate is employed as a corrosion inhibitor in automotive antifreeze and as a medication in certain pharmaceutical formulations.
Sodium benzoate is a also the preservative found in many foods and soft drinks.

Many soft drinks contain Sodium benzoate as both a preservative, and to enhance the flavour effect of their high-fructose corn syrup. 
Sodium benzoate is most commonly added to acidic foods like cider vinegars, pickles, condiments, jams and conserves, and soy sauce to control mold, bacteria, yeasts, and other microbes. 

Sodium benzoate interferes with their ability to make energy. 
Sodium benzoate only converts to benzoic acid in acidic environments, Sodium benzoate is not used for its anti-microbial action unless the pH is below about 3.6.

Sodium benzoate is commonly used as a preservative in non-alcoholic beverages such as soft drinks, energy drinks, sports drinks, and flavored water. 
Sodium benzoate is primarily used as a preservative in various food and beverage products. 

Sodium benzoate helps to prevent the growth of microorganisms, extending the shelf life of these products. 
Sodium benzoate is commonly found in carbonated drinks, fruit juices, jams, jellies, salad dressings, condiments, and processed foods.

Sodium benzoate is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited.
Sodium benzoate is also an important preservative of acid type food. 

Sodium benzoate transforms into effective form of benzoic acid during application. 
Sodium benzoate agent is a very important preservative of acid type fodder. 

Production Methods of Sodium benzoate:
Neutralized by benzoic acid and sodium bicarbonate. 
Put water and sodium bicarbonate into the neutralizing pot, boil Sodium benzoate and make it dissolved into sodium bicarbonate solution. 

Mix Sodium benzoate with benzoic acid until PH value of the reaction solution reaches to 7-7.5. 
Heat Sodium benzoate to emit over carbon dioxide, and then add active carbon to decolorize it for half an hour. 

Do suction filtration, after filtrate gets concentrated, put Sodium benzoate into flaker tray, dry it to be sheets in the drum, crush it, and then Sodium benzoate is made. 
Consumption rate of benzoic acid (99.5%) 1045kg/t and sodium bicarbonate (98%) 610kg/t.

Use 32% soda solution to neutralize benzoic acid in the pot to reach PH value of 7.5, and neutralization temperature is 70℃. 
Use 0.3% active carbon to decolorize the neutralized solution, vacuum filter it, concentrate, dry it and then it comes to powdered Sodium benzoate.
C6H5COOH+Na2CO3→C6H5COONa

To get it by toluene oxidation made benzoic acid reacting with sodium bicarbonate, sodium carbonate or sodium hydroxide.
Sodium benzoate is prepared by adding benzoic acid to a hot concentrated solution of sodium carbonate until effervescence ceases. 
The solution is then evaporated, cooled and allowed to crystallize or evaporate to dryness, and then granulated.

Stability and Reactivity of Sodium benzoate:

Chemical Stability:
Stable under normal conditions.

Reactivity:
Hazardous polymerization is not expected.

Conditions to Avoid:
Excessive heat, moisture, and dust generation.

Incompatible Materials:
Strong oxidizing agents and acids.

Hazardous Decomposition Products:
Carbon monoxide and carbon dioxide.

Handling and Storage of Sodium benzoate:

Safe Handling:
Ensure ventilation and avoid inhaling dust or contacting eyes and skin.

Storage Conditions:
Keep tightly closed in a cool, dry, ventilated place away from incompatible materials.

First Aid Measures of Sodium benzoate:

Inhalation:
Move to fresh air.
Seek medical attention if symptoms occur.

Skin Contact:
Rinse thoroughly with water.
Seek advice for persistent irritation.

Eye Contact:
Flush with water for at least 15 minutes and obtain medical attention.

Ingestion:
Rinse mouth and seek medical advice if symptoms develop.

Firefighting Measures of Sodium benzoate:

Suitable Extinguishing Media:
Water spray, carbon dioxide, dry chemical, or alcohol-resistant foam.

Specific Hazards:
Heating may release irritating gases.

Protective Equipment:
Use self-contained breathing apparatus and protective clothing.

Accidental Release Measures of Sodium benzoate:

Personal Precautions:
Wear protective equipment and minimize dust.

Environmental Precautions:
Avoid environmental release.

Cleanup Methods:
Collect carefully into closed waste containers.

Exposure Controls/Personal Protection of Sodium benzoate:

Engineering Controls:
Provide ventilation and accessible eyewash facilities.

Eye Protection:
Safety goggles.

Skin Protection:
Protective gloves and clothing.

Respiratory Protection:
Approved particulate respirator when exposure requires it.

Hygiene Measures:
Wash after handling.

Identifiers of Sodium Benzoate:
CAS Number: 532-32-1 
CHEBI:113455
ChEMBL1356 
ChemSpider: 10305 
ECHA InfoCard: 100.007.760 
E number: E211 (preservatives)
PubChem CID: 517055
RTECS number: DH6650000
UNII: OJ245FE5EU 
DTXSID1020140 

CAS Number: 532-32-1
Molecular Weight: 144.10
EC Number: 208-534-8

CAS number: 532-32-1
EC number: 208-534-8
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code    2916: 31 00

SCAS Number:532-32-1
Molecular Weight:144.10
Beilstein:3572467
EC Number:208-534-8
MDL number:MFCD00012463
eCl@ss:39024301
PubChem Substance ID: 329751625
NACRES: NA.21o

Properties of Sodium Benzoate:
Chemical formula: C7H5NaO2
Molar mass: 144.105 g·mol−1
Appearance: white or colorless crystalline powder
Odor: odorless
Density: 1.497 g/cm3
Melting point: 410 °C (770 °F; 683 K)
Solubility in water: 62.65 g/100 mL (0 °C)
62.84 g/100 mL (15 °C)
62.87 g/100 mL (30 °C)
74.2 g/100 mL (100 °C)[1]
Solubility: soluble in liquid ammonia, pyridine
Solubility in methanol: 8.22 g/100 g (15 °C)
7.55 g/100 g (66.2 °C)
Solubility in ethanol    
2.3 g/100 g (25 °C)
8.3 g/100 g (78 °C)
Solubility in 1,4-Dioxane: 0.818 mg/kg (25 °C

Density: 1.50 g/cm3 (20 °C)
Ignition temperature    >500 °C
Melting Point: 436 °C
pH value: 8 (100 g/l, H₂O, 20 °C)
Bulk density: 350 kg/m3
Solubility: 556 g/l

Computed Properties of E 211 (Sodium Benzoate)
Molecular Weight: 144.10    
Hydrogen Bond Donor Count: 0    
Hydrogen Bond Acceptor Count: 2    
Rotatable Bond Count: 1    
Exact Mass: 144.01872368    
Monoisotopic Mass: 144.01872368    
Topological Polar Surface Area: 40.1 Ų    
Heavy Atom Count: 10    
Complexity: 108    
Isotope Atom Count: 0    
Defined Atom Stereocenter Count: 0    
Undefined Atom Stereocenter Count: 0    
Defined Bond Stereocenter Count: 0    
Undefined Bond Stereocenter Count: 0    
Covalently-Bonded Unit Count: 2    
Compound Is Canonicalized: Yes 

Specifications of Sodium Benzoate:
Assay (acidimetric, calc. on anhydrous substance): 99.0 - 100.5 %
Assay (HPLC, calc. on anhydrous substance): 99.0 - 101.0 %
Identity: passes test
Appearance of solution (100 g/l, water)    passes test
Acidity or alkalinity: passes test
Chloride (Cl): ≤ 0.02 %
Sulphate (SO₄): ≤ 0.01 %
Total chlorine: ≤ 0.03 %
Heavy metals (as Pb): ≤ 10 ppm
As (Arsenic): ≤ 1 ppm
Cd (Cadmium): ≤ 10 ppm
Cu (Copper): ≤ 10 ppm
Hg (Mercury): ≤ 1 ppm
Pb (Lead): ≤ 2 ppm
Zn (Zinc): ≤ 10 ppm
Benzene: ≤ 2 ppm
Toluene: ≤ 890 ppm
Other residual solvents (ICH Q3C): excluded by production process
Multinuclear acids: passes test
Oxidizable matter: passes test
Water (according to Karl Fischer): ≤ 1.5 %Product Information
CAS number: 532-32-1
EC number: 208-534-8
Grade: Ph Eur,BP,NF,FCC,E 211
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code: 2916 31 00
 

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