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SODIUM BENZOIC ACID

Sodium benzoic acid works by disrupting the metabolic processes of microorganisms, thus preventing their growth and spoilage of food products.
Sodium benzoic acid is particularly effective in acidic conditions, which makes it suitable for use in acidic foods and beverages such as soft drinks, fruit juices, pickles, and condiments.
Sodium benzoic acid is considered safe for consumption when used within the approved limits set by regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).

CAS Number: 532-32-1
EC Number: 208-534-8
Molecular Formula: C7H5NaO2
Molecular Weight: 144.10317

Synonyms: Sodium benzenecarboxylate, 532-32-1, Sobenate, Antimol, Benzoic acid, sodium salt, Benzoic acid sodium salt, Benzoate sodium, Benzoate of soda, Benzoate, sodium, sodium;benzoate, Sodiumbenzoate, Natrium benzoicum, FEMA No. 3025, Fuminaru, Benzoan sodny, Caswell No. 746, Microcare sb, PUROX S, FEMA Number 3025, Benzoan sodny [Czech], CCRIS 3921, HSDB 696, Benzoesaeure (na-salz), UNII-OJ245FE5EU, EINECS 208-534-8, OJ245FE5EU, benzoic acid sodium, EPA Pesticide Chemical Code 009103, INS NO.211, DTXSID1020140, E211, AI3-07835, Benzoesaeure (na-salz) [German], INS-211, DTXCID90140, Sodium benzenecarboxylate [USAN:JAN], E-211, CHEBI:113455, Sodium benzenecarboxylate [USAN:JAN:NF], EC 208-534-8, AMMONUL COMPONENT Sodium benzenecarboxylate, UCEPHAN COMPONENT Sodium benzenecarboxylate, Sodium benzenecarboxylate COMPONENT OF AMMONUL, Sodium benzenecarboxylate COMPONENT OF UCEPHAN, Sodium benzoic acid, Sodium benzenecarboxylate (II), Sodium benzenecarboxylate [II], Sodium benzenecarboxylate (MART.), Sodium benzenecarboxylate [MART.], Sodium benzenecarboxylate (EP MONOGRAPH), Sodium benzenecarboxylate [EP MONOGRAPH], C7H5NaO2, MFCD00012463, BzONa, monoSodium benzenecarboxylate, Sodium benzenecarboxylate USP, Sodium benzenecarboxylate,(S), Sodium benzenecarboxylate (TN), SCHEMBL823, CHEMBL1356, Sodium benzenecarboxylate [MI], Sodium benzenecarboxylate (JP17/NF), Sodium benzenecarboxylate [FCC], Sodium benzenecarboxylate [JAN], C7-H6-O2.Na, Sodium benzenecarboxylate [FHFI], Sodium benzenecarboxylate [HSDB], Sodium benzenecarboxylate [INCI], Sodium benzenecarboxylate [USAN], Sodium benzenecarboxylate [VANDF], Sodium benzenecarboxylate [USP-RS], Sodium benzenecarboxylate [WHO-DD], Sodium benzenecarboxylate (Fragrance Grade), Benzoic acid, sodium salt (1:1), HY-Y1316, Tox21_300125, Sodium benzenecarboxylate [ORANGE BOOK], AKOS003053000, AKOS015890021, CCG-266169, LS-2390, NCGC00254072-01, CAS-532-32-1, CS-0017788, E 211, FT-0645126, S0593, D02277, A829462, Q423971, J-519752.

Sodium benzoic acid determination in fruit juices, sodas, soy sauce, ketchup, peanut butter, cream cheese and other foods by HPLC method has been proposed. 
Sodium benzoic acid is a Food and Drug Administration-approved nontoxic drug.

Sodium benzoic acid is used as a preservative in both cosmetics and food products, where it prevents both bacterial and fungal growth, though it is more active against the latter. 
Sodium benzoic acid is also used as a preservative in food and drink.

Sodium benzoic acid is a popular ingredient in cosmetics, not because of some amazing skin care property but because it works as a preservative.
Sodium benzoic acid an active ingredient in a skin care product like a nutrient or vitamin is used to nourish your skin cells, chances are the same nutrients also make good food for microbes in the air which can colonise your product and turn it mouldy. 

By including Sodium benzoic acid alongside the active ingredient, you can extend the life span of the product and fight off the growth of mould.
Sodium benzoic acid can be obtained via acid-base reaction between benzoic acid and sodium bicarbonate/sodium hydroxide solution.
Sodium benzoic acid is the salt of benzoic acid, an acid that is found naturally in foods like cranberries, apricots, mushrooms, and honey.

The U.S. Food and Drug Administration (FDA) has designated it a “generally recognised as safe” ingredient.
Sodium benzoic acid is a food additive used as preservative in acidic food and drinks – mostly those with a pH of less than 5.

Added as an anti-fungal, Sodium benzoic acid is used to balance the pH inside individual cells, raising the overall acidity of the product and creating an environment in which it is more difficult for fungi to grow. 
These fungi can invade food and cause Sodium benzoic acid to spoil, dramatically reducing its shelf life.

Sodium benzoic acid is a common food preservative and additive that is widely used in the food and beverage industry. 
Sodium benzoic acid is the sodium salt of benzoic acid and has the chemical formula C7H5NaO2. 

Sodium benzoic acid is a white, odorless, and crystalline powder that is highly soluble in water.
One of the primary reasons for using Sodium benzoic acid as a preservative is its ability to inhibit the growth of bacteria, yeast, and fungi. 
Sodium benzoic acid is particularly effective in acidic conditions, which makes it suitable for use in acidic foods and beverages such as soft drinks, fruit juices, pickles, and condiments. 

Sodium benzoic acid works by disrupting the metabolic processes of microorganisms, thus preventing their growth and spoilage of food products.
Sodium benzoic acid is important to note that Sodium benzoic acid is considered safe for consumption when used within the approved limits set by regulatory authorities, such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). 

Some individuals may be sensitive or allergic to Sodium benzoic acid, and in rare cases, Sodium benzoic acid can cause adverse reactions or exacerbate certain health conditions.
Sodium benzoic acid is always recommended to read food labels and consult with healthcare professionals if you have any concerns.

Sodium benzoic acid is the sodium salt form of benzoic acid, and is synthesized by reacting benzoic acid with sodium hydroxide. 
While Sodium benzoic acid must be manufactured, benzoic acid is found naturally in certain foods such as apples, prunes, plums, greengages, cloves and certain berries.

The independent Cosmetic Ingredient Review panel has ruled Sodium benzoic acid safe as used in cosmetics, where maximum usage levels range from 0.5–1%. 
In its raw form, Sodium benzoic acid is a white, crystalline solid that dissolves in water.

Sodium benzoic acid is the sodium salt of benzoic acid, widely used as a food preservative (with an E number of E211) and a pickling agent. 
Sodium benzoic acid appears as a white crystalline chemical with the formula C6H5COONa.

Glyceryl monostearate is not considered highly flammable. 
Sodium benzoic acid has a relatively high flash point and is not expected to contribute significantly to fire hazards. 

However, like any organic compound, Sodium benzoic acid can burn under certain conditions. 
Sodium benzoic acid is important to handle and store glyceryl monostearate away from open flames and ignition sources.

Sodium benzoic acid is generally stable under normal conditions.
Sodium benzoic acid can undergo decomposition at high temperatures, which may release potentially hazardous by-products. 

Sodium benzoic acid is important to avoid excessive heat or prolonged exposure to high temperatures.
While Sodium benzoic acid is considered safe for consumption and use in regulated concentrations, individuals with specific health conditions or allergies may experience adverse effects. 

If have a known sensitivity or allergy to glyceryl monostearate or related substances, Sodium benzoic acid is advisable to avoid products containing it and consult with a healthcare professional.
Sodium benzoic acid is subject to regulations and restrictions set by different regulatory bodies depending on the country or region. 

These regulations typically define the permitted concentrations, uses, and labeling requirements. 
Sodium benzoic acid is important for manufacturers and formulators to comply with these regulations to ensure the safe use of Sodium benzoic acid in consumer products.

Sodium benzoic acid is a sodium salt of benzoic acid, that is freely soluble in water compared to benzoic acid. 
Sodium benzoic acid is generally used as an antimicrobial preservative in cosmetics, food, and pharmaceuticals.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Sodium benzoic acid, also known as benzoic acid sodium, is commonly used as food preservatives in food industry, odorless or with slight smell of benzoin, and tastes sweet astringency. 

Stable in air, can absorb moisture in open air. 
Sodium benzoic acid’s naturally found in blueberry, apple, plum, cranberry, prunes, cinnamon and cloves, with weaker antiseptic performance than benzoic acid. 

Antiseptic performance of 1.180g Sodium benzoic acid is equivalent of about 1g benzoic acid. 
In acidic environment, Sodium benzoic acid have obvious inhibitory effect on a variety of microorganisms: when pH is at 3.5, 0.05% solution can completely inhibit the growth of yeast; while when pH is above 5.5, Sodium benzoic acid has poor effect on a lot of mold and yeast; hardly has any effect in alkaline solution. 

After Sodium benzoic acid enters into the body, in the process of biotransformation, it would combine with glycine to be uric acid, or combine with glucuronic acid to be glucosiduronic acid, and all to be eliminated from the body in urine, not to accumulate in the body. 
As long as Sodium benzoic acid is within the scope of the normal dosage, Sodium benzoic acid would be harmless to the human body, and it is a safe preservatives. 

Sodium benzoic acid also can be used for carbonated beverages, concentrated juice, margarine, chewing gum base, jam, jelly, soy sauce, etc. Human acceptable daily intake (ADI) < 5 mg/kg body weight (take benzoic acid as calculation basis).
Sodium benzoic acid has big lipophilicity, and it is easy to penetrate cell membrane into the cells, interfere in permeability of cell membrane, and inhibit cell membrane’s absorption of amino acids; cause Ionization acidification of alkaline storage in the cell when entering into, inhibit activity of respiratory enzymes, and stop condensation reaction of acetyl coenzyme A, and thereby achieve the purpose of food  antiseptic.

Sodium benzoic acid is commonly produced by the neutralization of sodium hydroxide (NaOH) with benzoic acid (C6H5COOH), which is itself produced commercially by partial oxidation of toluene with oxygen.
Sodium benzoic acid is a widely used food preservative, with an E number of E211. 

Sodium benzoic acid is the sodium salt of benzoic acid and exists in this form when dissolved in water. 
Sodium benzoic acid can be produced by reacting sodium hydroxide with benzoic acid.

Sodium benzoic acid is a salt made of sodium and benzoic acid.
Sodium benzoic acid can be found naturally in fruit and spices like apples, cranberries and cinnamon. 
Despite being naturally occurring, Sodium benzoic acid is usually synthesised in a lab when needed in large quantities for cosmetics. 

Sodium benzoic acid is a synthetic chemical produced when benzoic acid, which is found naturally in some fruits and spices, is combined with sodium hydroxide. 
Sodium benzoic acid is a preservative that can be found in acidic foods such as salad dressings, carbonated drinks, jams, juices, and condiments.

Sodium benzoic acid is also found in mouthwashes, silver polishes, cough syrups, soaps, and shampoos.
Sodium benzoic acid does not occur naturally, but benzoic acid is found in many plants, including cinnamon, cloves, tomatoes, berries, plums, apples, and cranberries (2Trusted Source).

Sodium benzoic acid is synthesised or artificially prepared from the substances benzoic acid and sodium hydroxide.
Additionally, certain bacteria produce benzoic acid when fermenting dairy products like yogurt (1, 3Trusted Source).

Sodium benzoic acid is used as an antifungal preservative in cosmetics and in food under the name E211. 
Sodium benzoic acid is therefore very effective against fungi, yeasts and bacteria. 

Sodium benzoic acid is made quite easily with soda, water and benzoic acid. 
Sodium benzoic acid is found naturally in some fruits such as plums, prunes or apples.

Sodium benzoic acid is an organic alcohol found in many fruits and teas. 
Sodium benzoic acid has a hydroxyl group (-OH), while the related compound, Benzoic Acid has a carboxyl group (-COOH). 

Sodium benzoic acid, Calcium Benzoate and Potassium Benzoate are salts of Benzoic Acid.
Sodium benzoic acid is an ester of Benzyl Alcohol and Benzoic Acid.

Sodium benzoic acid, also known as Benzoic acid sodium salt , can be made by chemically by reacting sodium hydroxide with Benzoic acid. 
Sodium benzoic acid is odorless or with a slight smell of Benzoin, and tastes sweet astringency. 

Stable in air Sodium benzoic acid can absorb moisture in open air as a preservative Sodium benzoic acid is bacteriostatic and fungistatic under acidic conditions. 
Sodium benzoic acid as a food additive, Sodium benzoic acid has the E number E211.

Since Sodium benzoic acid contains a natural ingredient, Sodium benzoic acid is probably safe, right? After all, the US Food and Drug Administration (FDA) and the Canadian Health Protection Branch have pronounced this chemical preservative to be acceptable when consumed in low amounts.
Sodium benzoic acid is a preservative added to some sodas, packaged foods, and personal care products to prolong shelf life.

Sodium benzoic acid is best known as a preservative used in processed foods and beverages to extend shelf life, though it has several other uses.
Sodium benzoic acid is a common food preservative and a mold inhibitor. 

Sodium benzoic acid is most effective in low acid foods and beverages and baked goods such as breads, cakes, pies, tortillas and many others.
Sodium benzoic acid’s an odorless, crystalline powder made by combining benzoic acid and sodium hydroxide. 

Sodium benzoic acid is a good preservative on its own, and combining it with sodium hydroxide helps it dissolve in products.
When Sodium benzoic acid is combined with ascorbic acid (vitamin C) in acidic conditions, such as in certain beverages, it can form Sodium benzoic acid. 

Sodium benzoic acid is a known carcinogen and may pose health risks if consumed in excessive amounts. 
There have been claims that Sodium benzoic acid, along with certain food colorings, may contribute to hyperactivity or attention deficit hyperactivity disorder (ADHD) symptoms in some susceptible individuals, particularly in children. 

Sodium benzoic acid, the scientific evidence regarding this link is limited and inconclusive.
While the risk is low when used within regulatory limits, under certain conditions (such as exposure to heat, light, or acidic conditions), Sodium benzoic acid can react with other ingredients to form benzene. 

Sodium benzoic acid is a potent carcinogen and should be minimized in food and beverage products. 
Regulatory authorities monitor and set limits on the amount of benzene allowed in consumer products.

Uses of Sodium benzoic acid:
Sodium benzoic acid is most widely used in acidic foods such as salad dressings (for example acetic acid in vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (acetic acid), condiments, and frozen yogurt toppings. 
Sodium benzoic acid helps maintain the freshness and quality of these beverages by preventing microbial spoilage.

Sodium benzoic acid can be found in certain dairy products like yogurt, cheese, and ice cream. 
Sodium benzoic acid helps prevent the growth of spoilage-causing microorganisms and extends the shelf life of these perishable products.

Many condiments and sauces, including ketchup, mayonnaise, mustard, and soy sauce, may contain Sodium benzoic acid as a preservative. 
Sodium benzoic acid helps prevent bacterial growth and maintains the flavor and quality of these products.

Sodium benzoic acid is sometimes used as a preservative in pet food and animal feed to ensure its safety and extend its shelf life. 
Sodium benzoic acid helps protect against the growth of bacteria and molds that can lead to spoilage and contamination.

In water treatment applications, Sodium benzoic acid can be used as a corrosion inhibitor and to control microbial growth in cooling towers and industrial water systems. 
Sodium benzoic acid helps prevent the formation of scale and biofilm, which can negatively impact system efficiency.

Sodium benzoic acid has been studied for its potential use as a plant growth regulator and for disease control in agriculture and horticulture. 
Sodium benzoic acid may have fungicidal properties and can be used to inhibit the growth of certain plant pathogens.

Sodium benzoic acid is sometimes used in fireworks compositions to produce green-colored flames when ignited. 
Sodium benzoic acid acts as a colorant and helps generate the desired visual effects.

Sodium benzoic acid is used in a variety of personal care products, including hair care products (shampoos, conditioners, styling products), skin care products (lotions, creams, cleansers), and oral care products (toothpaste, mouthwash). 
Sodium benzoic acid serves as a preservative to maintain the product's stability and prevent the growth of bacteria and fungi.

Sodium benzoic acid can be found in certain cleaning products, such as liquid soaps, detergents, and disinfectants. 
Sodium benzoic acid helps inhibit the growth of microorganisms and extends the shelf life of these products.

Sodium benzoic acid is utilized as a preservative in adhesives and sealants. 
Sodium benzoic acid helps prevent microbial growth, ensuring the integrity and stability of the product.

In the oil and gas sector, Sodium benzoic acid is sometimes used as a corrosion inhibitor in drilling fluids, production fluids, and pipeline systems. 
Sodium benzoic acid helps protect metal surfaces from corrosion caused by water, acids, and bacteria.

Sodium benzoic acid has been used in the photographic industry as a developing agent in certain photographic processes. 
with the advent of digital photography, its use in this industry has significantly declined.

Sodium benzoic acid can be used as a dye auxiliary in textile printing and dyeing processes. 
Sodium benzoic acid is also used as a preservative in medicines and cosmetics.

Sodium benzoic acid Under these conditions it is converted into benzoic acid (E210), which is bacteriostatic and fungistatic. 
Sodium benzoic acid is generally not used directly due to its poor water solubility. 

Concentration as a food preservative is limited by the FDA in the U.S. to 0.1% by weight.
Sodium benzoic acid is also allowed as an animal food additive at up to 0.1%, per the Association of American Feed Control Officials.

Sodium benzoic acid has been replaced by potassium sorbate in the majority of soft drinks in the United Kingdom.
Sodium benzoic acid is a preservative used in skincare products to prevent the overgrowth of microorganisms, Sodium benzoic acid is a mold inhibitor that helps to reduce the growth of mold and bacteria.

Sodium benzoic acid is widely used as a preservative in food, medicine, cosmetics and animal feeds. 
Sodium benzoic acid is used in the treatment of hyperammonemia and urea cycle disorders. 

Sodium benzoic acid is used in the fireworks as a fuel in whistle mix. 
Sodium benzoic acid is also used in the preparation of toothpaste and mouthwashes.

Sodium benzoic acid finds application in most of the acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments.
Sodium benzoic acid is produced by the neutralization of benzoic acid with sodium hydroxide.

Sodium benzoic acid also has applications beyond the food industry. 
Sodium benzoic acid is used in various personal care products, such as cosmetics, shampoos, and lotions, to inhibit the growth of bacteria and fungi. 

Sodium benzoic acid is employed as a corrosion inhibitor in automotive antifreeze and as a medication in certain pharmaceutical formulations.
Sodium benzoic acid is a also the preservative found in many foods and soft drinks.

Many soft drinks contain Sodium benzoic acid as both a preservative, and to enhance the flavour effect of their high-fructose corn syrup. 
Sodium benzoic acid is most commonly added to acidic foods like cider vinegars, pickles, condiments, jams and conserves, and soy sauce to control mold, bacteria, yeasts, and other microbes. 

Sodium benzoic acid interferes with their ability to make energy. 
Sodium benzoic acid only converts to benzoic acid in acidic environments, Sodium benzoic acid is not used for its anti-microbial action unless the pH is below about 3.6.

Sodium benzoic acid is commonly used as a preservative in non-alcoholic beverages such as soft drinks, energy drinks, sports drinks, and flavored water. 
Sodium benzoic acid is primarily used as a preservative in various food and beverage products. 

Sodium benzoic acid helps to prevent the growth of microorganisms, extending the shelf life of these products. 
Sodium benzoic acid is commonly found in carbonated drinks, fruit juices, jams, jellies, salad dressings, condiments, and processed foods.

Sodium benzoic acid is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited.
Sodium benzoic acid is also an important preservative of acid type food. 

Sodium benzoic acid transforms into effective form of benzoic acid during application. 
Sodium benzoic acid agent is a very important preservative of acid type fodder. 

Sodium benzoic acid transforms into effective form of benzoic acid during application. 
Sodium benzoic acid for application range and dosage.
In addition, Sodium benzoic acid also can be used as food preservative.

Sodium benzoic acid used in the research of pharmaceutical industry and plant genetic, also used as dye intermediates, fungicide and preservatives.
Sodium benzoic acid is used as food additive (preservative), fungicide in pharmaceutical industry, dye mordant, plasticizer in plastic industrial, and also used as organic synthetic intermediate of spices and others.

Sodium benzoic acid is a preservative. 
Sodium benzoic acid is bacteriostatic and fungistatic under acidic conditions. 

Sodium benzoic acid is most widely used in acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments. 
Sodium benzoic acid is also used as a preservative in medicines and cosmetics. 

As a food additive, Sodium benzoic acid has the E number E211.
Sodium benzoic acid is much better than benzoic acid at dissolving in water. 

Sodium benzoic acid is one of its most characteristic physical properties. 
Although the excipient Sodium benzoic acid conserves slightly better than Sodium benzoic acid, you can compensaté for this by either using a little more or lowering the pH by adding an acid to your product. 

Sodium benzoic acid is also used in fireworks as a fuel in whistle mix, a powder that emits a whistling noise when compressed into a tube and ignited. 
Sodium benzoic acid is also one of the fastest burning rocket fuels and provides a lot of thrust and smoke. 

Sodium benzoic acid does have its downsides: there is a high danger of explosion when the fuel is sharply compressed because of the fuel's sensitivity to impact.
Sodium benzoic acid can act as a food preservative. 

Production methods of Sodium benzoic acid:
Neutralized by benzoic acid and sodium bicarbonate. 
Put water and sodium bicarbonate into the neutralizing pot, boil Sodium benzoic acid and make it dissolved into sodium bicarbonate solution. 

Mix Sodium benzoic acid with benzoic acid until PH value of the reaction solution reaches to 7-7.5. 
Heat Sodium benzoic acid to emit over carbon dioxide, and then add active carbon to decolorize it for half an hour. 

Do suction filtration, after filtrate gets concentrated, put Sodium benzoic acid into flaker tray, dry it to be sheets in the drum, crush it, and then Sodium benzoic acid is made. 
Consumption rate of benzoic acid (99.5%) 1045kg/t and sodium bicarbonate (98%) 610kg/t.

Use 32% soda solution to neutralize benzoic acid in the pot to reach PH value of 7.5, and neutralization temperature is 70℃. 
Use 0.3% active carbon to decolorize the neutralized solution, vacuum filter it, concentrate, dry it and then it comes to powdered Sodium benzoic acid.
C6H5COOH+Na2CO3→C6H5COONa

To get it by toluene oxidation made benzoic acid reacting with sodium bicarbonate, sodium carbonate or sodium hydroxide.
Sodium benzoic acid is prepared by adding benzoic acid to a hot concentrated solution of sodium carbonate until effervescence ceases. 
The solution is then evaporated, cooled and allowed to crystallize or evaporate to dryness, and then granulated.

Safety Profile of Sodium benzoic acid:
Sodium benzoic acid is generally recognized as safe (GRAS) by regulatory authorities when used in accordance with approved limits.
The FDA and other regulatory agencies have set specific maximum levels for its use in food products. 

However, Sodium benzoic acid is worth noting that excessive consumption of foods and drinks containing Sodium benzoic acid, especially in combination with certain other substances, may have potential health effects. 
For instance, when Sodium benzoic acid is combined with ascorbic acid (vitamin C) or citric acid, Sodium benzoic acid can form benzene, a known carcinogen. 

To minimize the formation of benzene, manufacturers are required to limit the levels of these substances in products containing Sodium benzoic acid.
Ingested Sodium benzoic acid is conjugated with glycine in the liver to yield hippuric acid, which is excreted in the urine. 

Symptoms of systemic benzoate toxicity resemble those of salicylates. 
Whereas oral administration of the free-acid form may cause severe gastric irritation, benzoate salts are well tolerated in large quantities: e.g. 6 g of Sodium benzoic acid in 200mL of water is administered orally as a liver function test.

Clinical data have indicated that Sodium benzoic acid can produce nonimmunological contact urtcaria and nonimmunological immediate contact reactions. 
However, Sodium benzoic acid is also recognized that these reactions are strictly cutaneous, and Sodium benzoic acid can therefore be used safely at concentrations up to 5%. 

However, this nonimmunological phenomenon should be considered when designing formulations for infants and children.
Other adverse effects include anaphylaxis and urticarial reactions, although a controlled study has shown that the incidence of urticaria in patients given benzoic acid is no greater than that with a lactose  placebo.

Sodium benzoic acid has been recommended that caffeine and Sodium benzoic acid injection should not be used in neonates; however, Sodium benzoic acid has been used by others in the treatment of some neonatal metabolic disorders. 
Sodium benzoic acid has been suggested that there is a general adverse effect of benzoate preservatives on the behavior of 3-yearold children, which is detectable by parents, but not by a simple clinical assessment.

In combination with ascorbic acid (vitamin C, E300), Sodium benzoic acid and potassium benzoate form benzene, a known carcinogen. 
However, in most beverages that contain both, the benzene levels are below those considered dangerous for consumption. 

Heat, light and shelf life can affect the rate at which benzene is formed.
In the United States, Sodium benzoic acid is designated as generally recognized as safe (GRAS) by the Food and Drug Administration.

The International Programme on Chemical Safety found no adverse effects in humans at doses of 647–825 mg/kg of body weight per day.
Cats have a significantly lower tolerance against Sodium benzoic acid and its salts than rats and mice.

The human body rapidly clears Sodium benzoic acid by combining it with glycine to form hippuric acid which is then excreted.
The metabolic pathway for this begins with the conversion of benzoate by butyrate-CoA ligase into an intermediate product, benzoyl-CoA, which is then metabolized by glycine N-acyltransferase into hippuric acid.

Some individuals may be sensitive or allergic to Sodium benzoic acid. 
Allergic reactions can manifest as symptoms like skin rashes, itching, hives, swelling, respiratory difficulties, or gastrointestinal discomfort. 

Identifiers of Sodium benzoic acid:
CAS Number: 532-32-1 
CHEBI:113455
ChEMBL1356 
ChemSpider: 10305 
ECHA InfoCard: 100.007.760 
E number: E211 (preservatives)
PubChem CID: 517055
RTECS number: DH6650000
UNII: OJ245FE5EU 
DTXSID1020140 

CAS Number: 532-32-1
Molecular Weight: 144.10
EC Number: 208-534-8

CAS number: 532-32-1
EC number: 208-534-8
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code    2916: 31 00

SCAS Number:532-32-1
Molecular Weight:144.10
Beilstein:3572467
EC Number:208-534-8
MDL number:MFCD00012463
eCl@ss:39024301
PubChem Substance ID: 329751625
NACRES: NA.21o

Properties of Sodium benzoic acid:
Chemical formula: C7H5NaO2
Molar mass: 144.105 g·mol−1
Appearance: white or colorless crystalline powder
Odor: odorless
Density: 1.497 g/cm3
Melting point: 410 °C (770 °F; 683 K)
Solubility in water: 62.65 g/100 mL (0 °C)
62.84 g/100 mL (15 °C)
62.87 g/100 mL (30 °C)
74.2 g/100 mL (100 °C)[1]
Solubility: soluble in liquid ammonia, pyridine
Solubility in methanol: 8.22 g/100 g (15 °C)
7.55 g/100 g (66.2 °C)
Solubility in ethanol    
2.3 g/100 g (25 °C)
8.3 g/100 g (78 °C)
Solubility in 1,4-Dioxane: 0.818 mg/kg (25 °C

Density: 1.50 g/cm3 (20 °C)
Ignition temperature    >500 °C
Melting Point: 436 °C
pH value: 8 (100 g/l, H₂O, 20 °C)
Bulk density: 350 kg/m3
Solubility: 556 g/l

Computed Properties of E 211 (Sodium benzoic acid)
Molecular Weight: 144.10    
Hydrogen Bond Donor Count: 0    
Hydrogen Bond Acceptor Count: 2    
Rotatable Bond Count: 1    
Exact Mass: 144.01872368    
Monoisotopic Mass: 144.01872368    
Topological Polar Surface Area: 40.1 Ų    
Heavy Atom Count: 10    
Complexity: 108    
Isotope Atom Count: 0    
Defined Atom Stereocenter Count: 0    
Undefined Atom Stereocenter Count: 0    
Defined Bond Stereocenter Count: 0    
Undefined Bond Stereocenter Count: 0    
Covalently-Bonded Unit Count: 2    
Compound Is Canonicalized: Yes 

Specifications of Sodium benzoic acid:
Assay (acidimetric, calc. on anhydrous substance): 99.0 - 100.5 %
Assay (HPLC, calc. on anhydrous substance): 99.0 - 101.0 %
Identity: passes test
Appearance of solution (100 g/l, water)    passes test
Acidity or alkalinity: passes test
Chloride (Cl): ≤ 0.02 %
Sulphate (SO₄): ≤ 0.01 %
Total chlorine: ≤ 0.03 %
Heavy metals (as Pb): ≤ 10 ppm
As (Arsenic): ≤ 1 ppm
Cd (Cadmium): ≤ 10 ppm
Cu (Copper): ≤ 10 ppm
Hg (Mercury): ≤ 1 ppm
Pb (Lead): ≤ 2 ppm
Zn (Zinc): ≤ 10 ppm
Benzene: ≤ 2 ppm
Toluene: ≤ 890 ppm
Other residual solvents (ICH Q3C): excluded by production process
Multinuclear acids: passes test
Oxidizable matter: passes test
Water (according to Karl Fischer): ≤ 1.5 %Product Information
CAS number: 532-32-1
EC number: 208-534-8
Grade: Ph Eur,BP,NF,FCC,E 211
Hill Formula: C₇H₅NaO₂
Chemical formula: C₆H₅COONa
Molar Mass: 144.10 g/mol
HS Code: 2916 31 00
 

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