PRODUCTS

SODIUM GLUCONATE E576

Sodium Gluconate E576 is utilized across various industries with specific dosage rates depending on the application.
Sodium Gluconate E576 is often used in the food industry as a preservative and stabiliser.
Sodium Gluconate E576 is also used in the cosmetics industry as a humectant, i.e. a substance that prevents cosmetic products from drying out.

CAS Number: 527-07-1
EC Number: 208-407-7
MDL Number: MFCD00064210
IUPAC Name: Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
IUPAC Name: Sodium 2,3,4,5,6-pentahydroxyhexanoate
E number: E576 (acidity regulators, ...)
Chemical formula: C6H11NaO7
Molecular Weight: 218.14 g/mol

SYNONYMS:
Sodium Gluconate, D-Gluconic Acid Sodium Salt, Sodium D-Gluconate, Monosodium Gluconate, Gluconic Acid Sodium Salt, Sodium Salt of Gluconic Acid, E576, D-Gluconic acid sodium salt, Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, Gluconic acid, sodium salt, Sodium D-gluconate, E 576, Gluconic Acid Sodium Salt, Monosodium Gluconate, Sodium Fluconate, Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, Sodium D-gluconate, SODIUM GLUCONATE, 527-07-1, Sodium D-gluconate, D-Gluconic acid, monosodium salt, D-Gluconic acid sodium salt, Monosodium gluconate, gluconate sodium, Gluconic acid sodium salt, Glonsen, Monosodium D-gluconate, D-Gluconic acid, sodium salt, Gluconate (sodium), D-Gluconate sodium salt, D-Gluconic acid, sodium salt (1:1), Gluconic acid, monosodium salt, D-, Bvd addicrete, Clewat gl, Helshas a, Natrum gluconicum, sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, DTXSID7027170, CHEBI:84997, Sodium gluconate [USP], EINECS 238-976-7, MFCD00064210, 14906-97-9, D-Gluconic acid, sodium salt (1:?), R6Q3791S76, SODIUM GLUCONATE [II], SODIUM GLUCONATE [FCC], DTXCID007170, INS NO.576, sodium;(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, FEMA NO. 4934, SODIUM GLUCONATE [VANDF], SODIUM GLUCONATE [MART.], INS-576, GLUCONATE SODIUM [WHO-DD], 2,3,4,5,6-Pentahydroxycaproic acid sodium salt, SODIUM GLUCONATE [ORANGE BOOK], GLUCONIC ACID SODIUM SALT [MI], SODIUM GLUCONATE [USP MONOGRAPH], NCGC00164076-01, Sodium gluconate (USP), E-576, Gluconic acid, sodium salt, E-576-, NSC-759599, SODIUM GLUCONATE (II), C6H11NaO7, Pasexon 100T, SODIUM GLUCONATE (MART.), D-Gluconic acid sodium salt;Sodium D-gluconate;D-Gluconate sodium salt, SODIUM GLUCONATE (USP MONOGRAPH), Gluconato di sodio, Gluconato di sodio [Italian], EINECS 208-407-7, UNII-R6Q3791S76, Sodium Dgluconate, Monosodium Dgluconate, SCHEMBL23640, Sodium salt of D-gluconic acid, DGluconic acid, monosodium salt, SODIUM GLUCONATE [INCI], CHEMBL1200919, HY-B1092A, DTXSID00894961, Gluconic acid, monosodium salt, D, Tox21_112081, DGluconic acid, sodium salt (1:1), s4174, AKOS015899031, AKOS015951225, CCG-229938, CS-4777, NSC 759599, AS-11680, CAS-527-07-1, DA-57972, MG170849, G0041, NS00074302, D05862, Q264552, 208-407-7, 238-976-7, 692-539-9, D-Gluconic acid; monosodium salt, D-Gluconic acid sodium salt, D-Gluconic acid sodium salt, Sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate, Gluconic acid, sodium salt, Sodium D-gluconate, Sodium Citrate, Sodium Glucoheptonate, Lignosulfonates, Phosphonates (ATMP, HEDP)

Sodium Gluconate E576 is the sodium salt of gluconic acid, produced by fermentation of glucose.
Sodium Gluconate E576 is a white to tan, granular to fine, crystalline powder, very soluble in water.
Sodium Gluconate E576 is a non corrosive, non-toxic and readily biodegradable (98% after 2 days), Sodium Gluconate E576 is more and more appreciated as chelating agent.

The outstanding property of Sodium Gluconate E576 is its excellent chelating power, especially in alkaline and concentrated alkaline solutions.
Sodium Gluconate E576 forms stable chelates with calcium, iron, copper, aluminium and other heavy metals.
For highly alkaline solutions, Sodium Gluconate E576 surpasses all other chelating agents, such as EDTA, NTA and related compounds.

Aqueous solutions of Sodium Gluconate E576 are resistant to oxidation and reduction, even at high temperatures.
However, Sodium Gluconate E576 is easily degraded biologically (98% after 2 days), and thus presents no wastewater problem.
Sodium Gluconate E576 is also a highly efficient set retarder and a good plasticiser / water reducer for concrete, mortar and gypsum.

And last but not least, Sodium Gluconate E576 has the property to mask bitterness in food products.
Sodium Gluconate E576 is a polyhydroxy sodium carboxylate; it is also called sodium pentahydyoxy caproate.
The molecular formula of Sodium Gluconate E576 is C6H11O7Na; the molecular weight is 218.14; and it is white or light yellow crystalline particles or powder in appearance, easily soluble in water, slightly soluble in alcohol, and insoluble in ether.

Sodium Gluconate E576, also designated as E576, is the salt of gluconic acid and sodium.
Sodium Gluconate E576 is a white, crystalline substance with hygroscopic properties, meaning that it readily absorbs moisture from the environment.
Sodium Gluconate E576 is the sodium salt of gluconic acid, produced by fermentation of glucose.

Sodium Gluconate E576 is a white, granular to fine, crystalline powder, very soluble in water.
Sodium Gluconate E576 is a non-corrosive, non-toxic and readily biodegradable (98 % after 2 days), Sodium Gluconate E576 is more and more appreciated as chelating agent.
Sodium Gluconate E576 has a non-irritating, non-bitter, non sour, sligthly salty taste.

The outstanding property of Sodium Gluconate E576 is its excellent chelating power.
Sodium Gluconate E576 forms stable chelates with calcium, iron, copper, aluminium and other heavy metals, and surpasses all other chelating agents, such as EDTA, NTA and related compounds.

Aqueous solutions of Sodium Gluconate E576 are resistant to oxidation and reduction, even at high temperatures.
Sodium Gluconate E576 is an organic sodium salt with D-gluconate as the counter ion.
Sodium Gluconate E576 has a chelator role.

Sodium Gluconate E576 is the sodium salt of gluconic acid (E574).
Sodium Gluconate E576 is readily soluble and breaks down in the gastrointestinal tract into gluconic acid and sodium, both of which pass into the bloodstream and are metabolized without issue.

No adverse effects are associated with Sodium Gluconate E576.
Sodium Gluconate E576, or sodium d-gluconate, the sodium salt of gluconic acid with the European food additive number E576, is different with other gluconates that can be used as a nutrient, this ingredient is mainly used as a chelating agent and cleaner in food and industrial uses.

Physical Appearance: Sodium Gluconate E576 is a white to off-white powder or granules, highly soluble in water, non-toxic, biodegradable.
Sodium Gluconate E576 is a compound with formula NaC6H11O7.
Sodium Gluconate E576 is the sodium salt of gluconic acid.

Sodium Gluconate E576's E number is E576.
Sodium Gluconate E576 is a white powder that is very soluble in water.
Sodium Gluconate E576 is an organic compound that can be found in most of the products we consume every day.

Sodium Gluconate E576, also referred to as E576, is produced by the fermentation of sugar and takes the form of a white to pale yellow crystalline powder with a slightly salty taste.
Sodium Gluconate E576 is a salt of gluconic acid, which is naturally occurring in fruits such as berries or citrus fruits.

In humans, Sodium Gluconate E576 is found in the intestinal microflora.
Sodium Gluconate E576 is also an active ingredient in various cleaning products.
Sodium Gluconate E576 is a safe substance that has been assessed by the European Food Safety Authority (EFSA) as harmless to human health.

Nevertheless, care must be taken to consume Sodium Gluconate E576 in reasonable quantities, as is the case with all other additives.
Sodium Gluconate E576 is a stability agent.
Sodium Gluconate E576 is a yellow, gray, or light yellowish green color in powder or granules form.

Sodium Gluconate E576 has a caramel-like odor and has a aqueous solution of glucose which increases stability.
Sodium Gluconate E576 is the sodium salt of gluconic acid, produced by fermentation of glucose.
Sodium Gluconate E576 offers an outstanding chelating power.

Sodium Gluconate E576 is a compound with formula NaC6H11O7.
Sodium Gluconate E576 is the sodium salt of gluconic acid.
Sodium Gluconate E576's E number is E576.

This white, water-soluble powder, Sodium Gluconate E576, has a wide range of applications across industries.
Originally derived from gluconic acid in the 19th century, Sodium Gluconate E576 is known for its chelating properties and is utilized as a chelating agent in various processes.

Sodium Gluconate E576 is the sodium salt of gluconic acid, a naturally derived organic acid produced primarily through the fermentation of glucose using microorganisms such as Aspergillus niger.
Sodium Gluconate E576 is a highly effective biodegradable chelating agent, sequestrant, and water-conditioning additive widely used in industrial, food, pharmaceutical, personal care, and construction applications.

Sodium Gluconate E576 is valued for its exceptional ability to bind polyvalent metal ions such as calcium, magnesium, iron, aluminum, and heavy metals, thereby preventing undesirable chemical reactions and improving the stability and performance of formulations.
Due to its excellent environmental profile, low toxicity, and high water solubility, Sodium Gluconate E576 is frequently selected as an environmentally friendly alternative to less biodegradable chelating agents.

In the food industry, Sodium Gluconate E576 is approved as food additive E576, where it functions as a sequestrant, acidity regulator, and stabilizer.
In industrial applications, Sodium Gluconate E576 improves cleaning efficiency, enhances concrete performance, prevents scale formation, and increases the effectiveness of detergents and water treatment chemicals.

USES and APPLICATIONS of SODIUM GLUCONATE E576:
Sodium Gluconate E576 is utilized across various industries with specific dosage rates depending on the application.
Sodium Gluconate E576 is often used in the food industry as a preservative and stabiliser.
Sodium Gluconate E576 is added to foods as a salt to improve taste and extend shelf life.

Sodium Gluconate E576 is also used in the cosmetics industry as a humectant, i.e. a substance that prevents cosmetic products from drying out.
Sodium Gluconate E576 is extensively used in household and industrial cleaning products where it functions as a highly effective chelating agent that binds calcium, magnesium, iron, and other metal ions.

By softening water and preventing mineral interference, Sodium Gluconate E576 significantly enhances the cleaning performance of surfactants and detergents while reducing scale formation and residue deposits.
Textiles: In textile dyeing and printing, Sodium Gluconate E576 is utilized as a chelating agent to improve color fastness.

Metallurgy: Sodium Gluconate E576 is employed for metal surface treatment and cleaning, particularly for steel surfaces.
Cleaning Products: Sodium Gluconate E576 can be found in cleaning agents for glass bottles and as a chelating agent in various cleaning formulations.
In the construction industry, Sodium Gluconate E576 serves as a concrete admixture and set retarder.

Sodium Gluconate E576 delays cement hydration in a controlled manner, allowing improved workability, easier placement, enhanced finishing characteristics, and higher ultimate compressive strength.
Sodium Gluconate E576 also reduces water demand and contributes to more uniform concrete curing.

Sodium Gluconate E576 is used in cereal products, dairy, infant food, beverages, and black olives.
Sodium Gluconate E576 finds applications in textile, metal surface treatment, cement, and more.
Moreover, Sodium Gluconate E576's non-toxic nature and biodegradability contribute to its use in environmentally conscious practices.

Water treatment formulations utilize Sodium Gluconate E576 to prevent scale formation, control metal ion precipitation, and improve corrosion inhibition in cooling towers, boilers, and industrial water systems.
Sodium Gluconate E576's excellent calcium-binding capacity makes it highly effective in hard water treatment.

Applications: Sodium Gluconate E576 is used in construction as a concrete additive for retardation and plasticization.
Sodium Gluconate E576 functions as a chelating agent in cleaning and detergent formulations and as a food additive (E576) for buffering and stabilization.
Sodium Gluconate E576 is widely used in textile dyeing, printing and metal surface water treatment.

Sodium Gluconate E576 is also used as a chelating agent, a steel surface cleaning agent, a cleaning agent for glass bottles, and as a chelating agent for cement, plating and alumina dyeing industries.
Within the textile industry, Sodium Gluconate E576 functions as a bleaching stabilizer, dyeing auxiliary, metal ion sequestrant, and cleaning agent during textile processing.

Sodium Gluconate E576 improves dye uniformity and prevents unwanted metal-induced discoloration.
Sodium Gluconate E576 is widely used in agricultural products (non-pesticides), antifreeze and defrosting products, building/construction materials, cleaning and upholstery care products.

Sodium Gluconate E576 is used in electrical and electronic products, industrial cleaners, laundry and dishwashing products, metal products, paints and coatings, personal care products, plastic and rubber products, water treatment products.
Sodium Gluconate E576 is used as a cleaner in coating processes, as a paint stripper and for surface treatments.

Application of Sodium Gluconate E576: s Steel surface cleaning agent.
Sodium Gluconate E576 is used as a cement admixture.
Sodium Gluconate E576 is used in Electroplating, film industry.

Sodium Gluconate E576 is widely used in the construction industry(As water reducing agent or cement setting retarder).
Sodium Gluconate E576 is used as a special cleaning agent for glass bottles.
Sodium Gluconate E576 is used as a water quality stabilizer and softener.

Sodium Gluconate E576 is a sequestering agent used to improve the quality and stability of food products.
Sodium Gluconate E576 is also used in sweeteners to mask their bitter aftertaste.
The food industry employs Sodium Gluconate E576 (E576) as a sequestrant, stabilizer, acidity regulator, and processing aid.

Sodium Gluconate E576 improves product stability by binding trace metals that could otherwise promote oxidation or discoloration.
In the food industry, Sodium Gluconate E576 is widely used as a food additive.
Sodium Gluconate E576 is commonly used as an acidity regulator, anti-caking agent and stabilizer in many food products, such as cheese, beverages, canned goods and sausage products.

Additional applications of Sodium Gluconate E576 include pharmaceutical formulations, cosmetics, personal care products, electroplating solutions, bottle washing, metal surface cleaning, ceramic manufacturing, pulp and paper processing, agricultural formulations, oil field chemicals, and numerous specialty industrial formulations where efficient metal ion control is required.
Sodium Gluconate E576 is a multi-functional ingredient that can be used in a lot of fields, commonly used for its outstanding chelating property in food and industrial uses.

Also used for Sodium Gluconate E576's PH buffering and taste improvement in food.
Sodium Gluconate E576's early uses were primarily in medicine due to its mild and non-toxic properties.

Over time, Sodium Gluconate E576's applications expanded to various industries, including food, pharmaceuticals, construction, textiles, and more, as its versatile properties and safety profile became more widely recognized.
Food industry: Sodium Gluconate E576 is used as a food additive for various purposes, including as a sequestrant to prevent metal ions from affecting the color, flavor, or stability of food products.

-Textile and Printing Industry uses of Sodium Gluconate E576:
Application: Water Hardness Sequestrant (Masking Agent) in Dye Baths.
Typical Dosage Rate: 0.5 - 2.0 g/L based on dye bath volume.
Details: Prevents metal ions in hard water from reacting with reactive dyes, which would otherwise cause color deviations and dullness.

-Industrial Water Treatment (Cooling Towers & Closed Loops) uses of Sodium Gluconate E576:
Application: Corrosion Inhibitor and Scale Preventer.
Typical Dosage Rate: 10 - 50 ppm (mg/L) in circulating water.
Details: Highly effective in preventing iron and copper corrosion in closed-loop systems, especially in high alkalinity environments.

-Key applications of Sodium Gluconate E576:
Raw materials for the metallurgical industry,
Raw materials for the food industry,
Raw materials for the construction chemistry production,
Raw materials for household chemicals production,
Raw materials for the production of adhesives, oils, lubricants,
Raw materials for fertilizer production,
Raw materials for plastics production

-Construction uses of Sodium Gluconate E576:
Sodium Gluconate E576 is employed in the construction industry as a concrete admixture.
Sodium Gluconate E576 acts as a water reducer and retarder, enhancing the workability and performance of concrete.

-Sodium Gluconate E576 can be used as:
A sequestrant agent by chelating undesirable metal ions.
A PH buffer in drink.
A taste improver for beverage by masking off-notes or reducing the bitterness/aftertaste from artificial sweeteners, soybean protein, minerals or caffeine.
A stabilizer in meat products by increasing meat water-binding capacity and improving its firmness and sliceability.
Meanwhile, Sodium Gluconate E576 is a replacement of phosphates.

-Pharma & Nutraceutical uses of Sodium Gluconate E576:
Sodium Gluconate E576 can be used as an excipient as a buffer and pH adjuster in the following products:
Syrups
Suspension
Swallowable/orally dispersible tablets
Hard capsules
Others

-Cosmetics uses of Sodium Gluconate E576:
Sodium Gluconate E576 functions as a chelating and skin conditioning in cosmetic and personal care products.
And usually we can find Sodium Gluconate E576 in skin care products like face cream, soap, and toothpaste.

-Chelating agent uses of Sodium Gluconate E576:
With good sequestering power (over EDTA, NTA and some other related compounds) to combine with di- and trivalent metal ions, such as calcium, iron, copper, aluminium to form stable chelates and take them out of water or the solution at an alkaline pH, and with little effect on temperature.

Due to this property, Sodium Gluconate E576 is widely used in:
Water treatment
Bottle washing
Corrosion inhibition
Metal surface treatment
Industrial cleaning
Concrete retarder
In addition, Sodium Gluconate E576 can be used in the construction industry, as a retarding cement enhancing additive

-Construction and Building Chemicals uses of Sodium Gluconate E576:
Application: Concrete Admixture (Set Retarder and Water Reducer)
Typical Dosage Rate: 0.05% - 0.30% by weight of total cementitious material.
Details: For extending setting time during hot weather or long hauls, a dosage of 0.15% - 0.30% is preferred.
Lower dosages (approx. 0.05%) primarily function as a plasticizer/water reducer.

-Industrial Cleaning and Metal Surface Treatment uses of Sodium Gluconate E576:
Application: Alkaline Cleaners (Bottle Washing, Metal Parts Cleaning)
Usage Method: Added to solutions containing Caustic Soda (NaOH).
Typical Dosage Rate:
Light Soils / Hard Water: 2% - 5% (of total solution volume)
Heavy Soils / Descaling Formulations: 5% - 10%
Brewery and Beverage Bottle Washing (High Water Hardness): 10% - 12%

SODIUM GLUCONATE E576 AND ITS FUNCTIONS IN FOODS:
As a food additive, Sodium Gluconate E576 plays an important role in regulating acidity, preventing product clumping and stabilization.
Sodium Gluconate E576 is an essential ingredient in the production of many food products, helping to maintain their quality and shelf life.

PROPERTIES of SODIUM GLUCONATE E576:
Sodium Gluconate E576 is easily soluble in water, making it easy to use in the food industry.
Sodium Gluconate E576 has hygroscopic properties, meaning it can absorb moisture, which is important for keeping food products moist.

KEY FUNCTIONAL PROPERTIES AND APPLICATIONS of SODIUM GLUCONATE E576:
Sector / Application Function
***Construction & Building Chemicals Set Retarder:
Sodium Gluconate E576 extends the workability time of concrete and mortar.
Water Reducer:
Sodium Gluconate E576 acts as a dispersant in high-performance concrete admixtures.
Note:
Sodium Gluconate E576 is an economical alternative to Lithium-based chemicals.

***Industrial Water Treatment Chelating Agent & Corrosion Inhibitor:
Sodium Gluconate E576 binds Calcium, Magnesium, and Iron ions in closed-loop cooling systems, preventing scale formation and corrosion.
Sodium Gluconate E576 is a more stable and biodegradable alternative to EDTA in highly alkaline environments.

***Metal Surface Treatment & Cleaning Alkaline Cleaner:
Sodium Gluconate E576 is used in bottle washing and metal cleaning baths with caustic soda.
Sodium Gluconate E576 prevents re-deposition of soils by chelating ions released from the metal surface.
Electroplating:
Bath stabilizer.

***Food Additive (E576) Synergist & Bitterness Masking:
Sodium Gluconate E576 suppresses the metallic aftertaste of sweeteners (such as Stevia).
Stabilizer:
Sodium Gluconate E576 is used in dairy products and confectionery.

***Textile and Printing Color Developer & Masking Agent:
Sodium Gluconate E576 removes water hardness in dye baths, ensuring brighter and more homogeneous colors.

PROPERTIES of SODIUM GLUCONATE E576:
Excellent chelating agent
Highly effective sequestrant
Excellent metal ion complexing ability

Strong calcium-binding capacity
Strong magnesium-binding capacity

Effective heavy metal chelator
Highly water soluble

Readily biodegradable
Environmentally friendly

Low toxicity
Noncorrosive in most applications

Excellent scale inhibitor
Excellent corrosion inhibitor

Good buffering properties
High formulation stability

Broad pH compatibility
Good thermal stability

Good hydrolytic stability
Excellent compatibility with detergent ingredients

Improves cleaning efficiency
Prevents mineral deposits

Prevents soap scum formation
Improves surfactant performance

Enhances bleaching efficiency
Stabilizes peroxide formulations

Excellent dispersing aid
Prevents precipitation of metal salts

Improves rinse performance
Reduces water hardness effects

Food-grade additive (E576)
Suitable for environmentally responsible formulations

CHARACTERISTICS of SODIUM GLUCONATE E576:
Sodium Gluconate E576 is one of the most versatile biodegradable chelating agents used in modern industrial and consumer formulations.
Sodium Gluconate E576's molecular structure contains multiple hydroxyl groups and one carboxylate group, enabling the formation of highly stable complexes with numerous multivalent metal ions.
This metal-binding capability significantly improves formulation stability by preventing unwanted precipitation, discoloration, oxidation, and catalytic degradation caused by trace metal contaminants.

Unlike many conventional chelating agents, Sodium Gluconate E576 is readily biodegradable and exhibits very low environmental toxicity, making it particularly attractive for environmentally conscious formulations.
Sodium Gluconate E576 performs effectively across a broad pH range and remains stable under alkaline conditions where many other chelating agents become less effective.

Sodium Gluconate E576 is highly soluble in water, easy to formulate, and compatible with a wide variety of industrial chemicals.
Sodium Gluconate E576's excellent sequestration efficiency improves the effectiveness of detergents, cleaners, water treatment chemicals, concrete admixtures, textile auxiliaries, and numerous specialty chemical formulations.

FUNCTIONS of SODIUM GLUCONATE E576:
Sodium Gluconate E576 offers you the following excellent functions.
Bitterness masking agent
Buffering agent
Chelating agent
Chelation
Flavour modulation
Off-note masking
pH-regulation
Phosphate replacement

PRODUCTION of SODIUM GLUCONATE E576:
Sodium Gluconate E576 can be produced by chemical synthesis, an enzymatic process, or fermentation, the last of which is used commercially.
In the fermentation process, glucose is fermented by microorganisms yielding gluconic acid.
Aspergillus niger and Gluconobacter oxidans are used in industry.
Sodium Gluconate E576 is derived by neutralizing gluconic acid with sodium hydroxide.

IS SODIUM GLUCONATE E576 SAFE TO EAT?
Yes, Sodium Gluconate E576 has been approved safe by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

PROPERTIES of SODIUM GLUCONATE E576:
Appearance
Sodium Gluconate E576 is a white to tan powder or granular.

Solubility
Sodium Gluconate E576 is very soluble in water, sparingly soluble in ethanol.

PH
Between 6.5 and 7.5 (10 % solution)

BENEFITS of SODIUM GLUCONATE E576:
Sodium Gluconate E576 provides outstanding metal ion sequestration, allowing formulations to maintain stability and performance even in hard water or metal-contaminated environments.
Its excellent biodegradability and low toxicity make Sodium Gluconate E576 an environmentally preferred alternative to many conventional chelating agents.

Sodium Gluconate E576 significantly improves detergent efficiency by preventing interference from calcium and magnesium ions while enhancing surfactant performance and reducing scale formation.
In construction applications, Sodium Gluconate E576 improves concrete workability, extends setting time under controlled conditions, and contributes to higher long-term strength.

Sodium Gluconate E576's exceptional compatibility with a wide range of formulation ingredients allows flexible product development across numerous industries.
Sodium Gluconate E576 also improves corrosion protection, reduces mineral deposits, stabilizes peroxide bleaching systems, enhances cleaning efficiency, and extends equipment service life by minimizing scale accumulation.

PRODUCTION METHOD of SODIUM GLUCONATE E576:
Chemical Synthesis:
Gluconic Acid solution is obtained by reacting Calcium Gluconate with Sulfuric Acid.
It is subsequently neutralized with Sodium Carbonate (Na₂CO₃), filtered, and dried in a spray dryer.

Biotechnological Method:
Produced via controlled fermentation of Glucose (Corn sugar) using specific bacterial or fungal strains (Aspergillus niger).

PHYSICAL and CHEMICAL PROPERTIES of SODIUM GLUCONATE E576:
IUPAC Name: Sodium 2,3,4,5,6-pentahydroxyhexanoate
Common Name: Sodium Gluconate
CAS Number: 527-07-1
EC Number: 208-407-7
E Number: E576
MDL Number: MFCD00064210
HS Code: 2918 16 00
Molecular Formula: C₆H₁₁NaO₇
Empirical Formula (Hill Notation): C6H11NaO7
Molecular Weight: 218.14 g/mol

Appearance: White to light beige crystalline powder
/ White or almost white, fine crystalline powder
Odor: Practically odorless
Odorless
Physical State: Solid, powder
Density: 1.79 g/cm³ at 20 °C
Melting Point: 205–209 °C
Boiling Point: Decomposes at 196–198 °C
Initial boiling point (calculated): 613.1 °C
Flash Point: Not applicable

Autoignition Temperature: >200 °C
Decomposition Temperature: 196–198 °C
Solubility in Water: Very soluble (590 g/L at 25 °C or 58 g/100 mL)
Solubility in Ethanol: Sparingly/slightly soluble
Solubility in Diethyl Ether: Practically insoluble
pH (100 g/L in water at 20 °C): 6.5–7.5 / 7.0–8.0
Partition Coefficient (log Pow): −5.99 → Very low bioaccumulation potential
Vapor Pressure: <0.1 hPa at 25 °C
Viscosity: No data available
[α]D²⁰: +11° to +13° (c = 10, H₂O)

Explosive Properties: Not classified as explosive
Oxidizing Properties: None
Ignition Temperature: >200 °C
Flash Point: Not applicable
Residual Solvents: Excluded by manufacturing process (per ICH Q3C)
Chloride (Cl): ≤ 0.04%
Sulfate (SO₄): ≤ 0.02%
Lead (Pb): ≤ 1 ppm
Reducing Substances: ≤ 0.5%
Assay (Perchloric Acid Titration): 99.0–102.0%
Identity (Wet Chemistry & TLC): Passing test

Molecular Weight: 218.14 g/mol
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 5
Exact Mass: 218.04024697 Da
Monoisotopic Mass: 218.04024697 Da
Topological Polar Surface Area: 141 Å²
Heavy Atom Count: 14
Formal Charge: 0

Complexity: 176
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 4
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
CAS number: 527-07-1
EC number: 208-407-7
Grade: And 576

Hill Formula: C₆H₁₁NaO₇
Molar Mass: 218.14 g/mol
HS Code: 2918 16 90
Density: 1.79 g/cm3 (20 °C)
Ignition temperature: >200 °C
Melting Point: 205 - 209 °C
pH value: 6.5 - 7.5 (H₂O)
Vapor pressure: <0.1 hPa (25 °C)
Solubility: 590 g/l

Appearance: White crystalline powder or granular solid
Color: White
Odor: Odorless
Taste: Slightly salty
Physical State: Solid
Molecular Formula: C₆H₁₁NaO₇
Molecular Weight: 218.14 g/mol
Density: Approximately 1.76 g/cm³
Bulk Density: Varies depending on particle size and grade

Melting Point: Decomposes upon heating (no true melting point)
Decomposition Temperature: Above approximately 200°C
Boiling Point: Not applicable (decomposes before boiling)
pH (10% aqueous solution): Typically 6.5–8.0
Solubility in Water: Highly soluble
Solubility in Alcohol: Slightly soluble
Solubility in Organic Solvents: Practically insoluble in most nonpolar organic solvents
Hygroscopicity: Slightly hygroscopic
Chelating Ability: Excellent for calcium, magnesium, iron, aluminum, copper, and heavy metals

Buffering Capacity: Moderate
Thermal Stability: Good under normal processing conditions
Hydrolytic Stability: Excellent
Oxidation Stability: Good
Biodegradability: Readily biodegradable
Surface Activity: Non-surfactant
Corrosion Inhibition: Excellent when used in suitable formulations
Scale Prevention: Excellent

Water Hardness Control: Excellent
Compatibility: Compatible with most anionic, nonionic, amphoteric, and many cationic formulation components
Toxicity: Low
Volatility: Nonvolatile
Electrical Conductivity: Conductive in aqueous solution due to sodium ions
Metal Ion Sequestration: Very high efficiency over a broad pH range
Stability in Alkaline Solutions: Excellent
Stability in Neutral Solutions: Excellent
Shelf Stability: Excellent under dry storage conditions

FIRST AID MEASURES of SODIUM GLUCONATE E576:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of SODIUM GLUCONATE E576:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of SODIUM GLUCONATE E576:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM GLUCONATE E576:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of SODIUM GLUCONATE E576:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of SODIUM GLUCONATE E576:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available