PRODUCTS

SODIUM L-ASCORBATE

Sodium L-Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
Sodium L-Ascorbate is a form of Vitamin C.
Sodium L-Ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).
TAs the sodium salt of ascorbic acid, it is known as a mineral ascorbate.he molecular formula of this chemical compound is C6H7NaO6.

CAS Number: 134-03-2
EC Number: 205-126-1
IUPAC Name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one;molecular hydrogen;sodium
Chemical Formula: C6H7O6Na

Other names: 0134-03-02, L-ascorbic Acid Sodium Salt, (+)-Sodium L-ascorbate, 11140_fluka, 129940-98-3, 156683-68-0, 2,3-Didehydro-3-O-natrio-D-erythro-hexono-1,4-lacton, 3-Hydroxy-4-(sodiooxy)-5-(1,2-dihydroxyethyl)furan-2(5H)-one, 3-oxo-l-gulofuranolactone Sodium, 50-81-7 (parent), 58657-35-5, 73. 884311-57-3, 7317-67-1, 884311-57-3, A0539, A4034_sigma, A7631_sigma, A806721, Akos015895058, AKOS016373592, Aminofenitrooxon, Antiscorbutic vitamin, Ascorbate De Sodium, Ascorbato Sodico, Ascorbic Acid Sodium Derivative, Ascorbicin, Ascorbin, ASK-P 10KR, Bp-30077, C6h7o6.na, Cas-134-03-2, Ccris 3291, Cebitate, Cenolate; E 301, Cevitamic acid, Chembl591665, CK 40, CK 40 (ascorbate), Dsstox_cid_105, Dsstox_gsid_20105, Dsstox_rid_75369, E 301 (Antioxidant), E301, Einecs 205-126-1, FT-0627703, HBL 508, Hsdb 694, Iskia C, l-Ascorbate, sodium, L-ascorbic Acid, Monosodium Salt, L-ascorbic Acid, Sodium Salt (1:1), L()-ascorbic Acid Sodium Salt, L(+)-Ascorbic acid sodium salt, Limcee, Ls-107459, Ls-2375, M609, MCULE-8774510897, Molport-003-925-923, Monosodium Ascorbate, Monosodium L-Ascorbate, natrascorb, Natri-C, Natrii Ascorbas, Ncgc00254355-01, Rp23764, S033eh8359, SCHEMBL19378674, Sodascorbate, sodium (2R)-2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, Sodium (2r)-2-[(1s)-1,2-bis(oxidanyl)ethyl]-4-oxidanyl-5-oxidanylidene-2h-furan-3-olate, Sodium (2r)-2-[(1s)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2h-furan-3-olate, Sodium Ascorbate, Sodium Derivative Of 3-oxo-l-gulofuranolactone, Sodium Vitamin-c, Tox21_300556, Unii-s033eh8359, Vitamin C Sodium, Vitamin- C Sodium Salt

Sodium L-Ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of Sodium L-Ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).
Sodium L-Ascorbate is ascorbic acid with a sodium molecule attached to help lessen its natural acidity.
Sodium L-Ascorbate is an ideal alternative to ascorbic acid if you find the pure form of vitamin C causes heartburn or other stomach upset.

Sodium L- Ascorbate is a buffered form of Vitamin C and as such, it is located in nature.
Sodium L-Ascorbate is a six carbon compound related to glucose.
Sodium L-Ascorbate is found naturally in citrus fruits and many vegetables.
L-Ascorbic acid sodium salt (Sodium L-ascorbate), an electron donor, is an endogenous antioxidant agent.
Sodium L-Ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C).

Sodium L-Ascorbate consists of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry.
Sodium L-Ascorbate is a mineral salt of Ascorbic Acid [Vitamin C] (A786990), a physiological antioxidant.
L-Ascorbic acid sodium salt inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM.

L-Ascorbic acid (Vitamin C) is a water soluble molecule use in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress.
Sodium L-Ascorbate is a weak base.
Sodium L-ascorbate is a white, small-grained crystalline powder used as a food additive to provide levels of vitamin C with reduced acidity and to extend the longevity of the color, aroma and nutrient content of the final product.

Solubility in Water: almost transparency
Melting Point: 218 °C
Specific Rotation: 105.5°
Molecular Weight: 198.11

Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 2
Exact Mass: 198.01403222

Monoisotopic Mass: 198.01403222
Topological Polar Surface Area: 110 Å²
Heavy Atom Count: 13
Complexity: 237
Undefined Atom Stereocenter Count: 2

Covalently-Bonded Unit Count: 2
Compound Is Canonicalize: Yes
Storage: 4°C, protect from light
Appearance :Crystalline powder

Physical State :Solid
Solubility :Soluble in Water: 50 mg/mL
Storage :Store at room temperature
Melting Point :220° C

Turbidity 10% aq. solution: Clear
pH (10% aq. solution): 7.0 - 8.0
Specific rotation [α]: +103 to +108° [C=10,water]
Loss on drying: max. 0.5%
Melting point: 220 °C (dec.)(lit.)
alpha: 104 º (c=1, H2O 25 ºC)

Boiling point: 235 °C
mp: 220 °C (dec.)
Density: 1.66
refractive index: 105.5 ° (C=10, H2O)
storage temp.: 2-8°C
solubility H2O: 50 mg/mL

color white to slightly yellow
PHpH (20g/l, 25℃) : 6.5～8.0
Odorodorless
optical activity[α]20/D: +105±2°, c = 5% in H2O
Water Solubility: 620 g/L (20 ºC)
Merck: 14,830

Storage: 0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Description: White to light brownish powder
Assay: 99.0 - 101.0%
Specific optical rotation: +103° to +108°

pH of 10% solution: 7.0 – 8.0
Loss on drying at 60°C: Max. 0.25%
Heavy Metals (as Pb): Max. 0.002%
Melting Point [°C]: 200°C

APPLICATIONS AND USES
(+)-Sodium L-ascorbate has been used:
as a component of cutting solution for storing brain slices of rats
as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices.
as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator.
Sodium L-Ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand.
L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor.
L-Ascorbic acid sodium salt is used as an antioxidant, an acidity regulator and an antimicrobial in food stuff.
As a reductant, Sodium L-Ascorbate is involved in the isolation of chloroplasts.

Sodium L-Ascorbate acts as a coenzyme for many hydroxylation reactions.
Sodium L-Ascorbate plays a vital role to eliminate chronic and acute infections.
Sodium L-Ascorbate is a coenzyme for a number of hydroxylation reactions required for collagen synthesis.
Sodium L-Ascorbate is widely distributed in plants and animals.
Sodium L-Ascorbate is used as an antimicrobial and antioxidant in foodstuffs.
Sodium L-Ascorbate is soluble in water and provides a non acidic taste. a 10% aqueous solution has a ph of 7.3–7.6.

In water, Sodium L-Ascorbate readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant.
The resulting solutions of Sodium L-Ascorbate contain moderate concentrations of hydroxide ions and have pH greater than 7.0.
Sodium L-Ascorbate reacts as bases to neutralize acids.

Neutralizations like Sodium L-Ascorbate generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
Sodium L-Ascorbate is used as an antioxidant in pharmaceutical formulations, and also in food products where it increases the effectiveness of sodium nitrite against growth of Listeria monocytogenes in cooked meats.
Sodium L-Ascorbate improves gel cohesiveness and sensory firmness of fiberized products regardless of vacuum treatment.

Sodium L-Ascorbate is also used therapeutically as a source of vitamin C in tablets and parenteral preparations.
Sodium L-Ascorbate preserves nitric oxide (NO) which may help prevent endothelial dysfunction, helps prevent and reverse the oxidative damage done to proteins and lipids as a result of cigarette smoke.
cell culture
(+)-Sodium L-ascorbate has been used to produce H2O2 in cell culture media, as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD), and to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat.

Sodium L-Ascorbate is used for preparation of plant extracts; reductant for the isolation of chloroplasts.
(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid).
In addition, Sodium L-Ascorbate enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture.

Sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.
Sodium L-Ascorbate is used in Miscellaneous, Household Chemicals, Food and Feed Additives.
Sodium L-Ascorbate is an antioxidants; free Radical Scavenger.
Ascorbic acid and calcium and Sodium L-Ascorbates are used as antioxidants in pharmaceutical manufacturing and in the food industry.

Sodium L-Ascorbate is used in food, beverage and dietary supplement applications as a Vitamin C source.
Some applications include chewable vitamins, processed meats, nutrient enhanced beverages and foods.
Sodium L-Ascorbate is used in dietary supplement applications including hard shell capsules and tablets.
Occasionally, Sodium L-Ascorbate is used for preservation of diagnostic medicinals.

Function:
to maintain the intercellular material;
A specific role in the synthesis of collagen, that is in the synthesis of the hydroxyproline or proline; In oxidation-reduction systems: glutathione, cytochrome C, pyridine or flavin nucleotides nucleoproteins; in the metabolism of adrenal steroids;
In the metabolism of various drugs.
Sodium L-Ascorbate increases the effectiveness of the immune system.
Sodium L-Ascorbate is an antioxidant, anti-aging material used in skin treatments, to boost collagen synthesis.

Sodium L-Ascorbate increases immune function
Sodium L-Ascorbate helps white blood cells function more effectively
Sodium L-Ascorbate protects against cough and common cold
Sodium L-Ascorbate improve iron absorption
Sodium L-Ascorbate can be used both as a nutrient (vitamin C) and as an additive (antioxidant).
Sodium L-Ascorbate might be beneficial over ascorbic acid because it is buffered by the sodium, making it less acidic.

PHYSICAL AND CHEMICAL PROPERTIES
Sodium L-Ascorbate is white to almost white powder to crystal.
Sodium L-Ascorbate is freely soluble in water; very slightly soluble in ethanol.
Sodium L-Ascorbate is relatively stable in air, although it gradually darkens on exposure to light.
Aqueous solutions are unstable and subject to rapid oxidation in air at pH > 6.0.
The bulk material should be stored in a well-closed nonmetallic container, protected from light, in a cool, dry place.