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Sodium Propionate is the salt form of propionic acid, which is an organic acid that is produced during the chemical degradation of sugar.
Sodium propionate is a compound that is produced naturally in the body when certain fatty acids and amino acids are metabolized.
Sodium Propionate is metabolized by a series of enzymatic reactions that are dependent on the presence of vitamin B-12, according to a 1996 article in the "International Journal of Vitamin and Nutrition Research.
CAS Number: 137-40-6
Molecular Formula: C3H6O2.Na
Molecular Weight: 96.06
EINECS Number: 205-290-4
Synonyms: SODIUM PROPIONATE, 137-40-6, Sodium propanoate, Propionic acid sodium salt, Propanoic acid, sodium salt, SODIUMPROPIONATE, Propionic acid, sodium salt, sodium;propanoate, Propanoic acid, sodium salt (1:1), Sodium propionate anhydrous, Natriumpropionat, Sodium hydrogen dipropionate, Sodium dipropionate, Propanoic acid, sodium salt (2:1), DK6Y9P42IN, Mycoban, Napropion, Ocuseptine, Ocuseptine, DTXSID7021996, Napropion, 63785-15-9, EINECS 264-460-6, Deketon, E281, Impedex, Keenate, Propiofar, Propisol, Propi-ophtal, Whit-pro, Bioban-S, DTXCID001996, SODIUM PROPIONATE-2,3-13C2, 99 ATOM % 13 C, Caswell No. 707A, Propionan sodny, Propionan sodny [Czech], Natriumpropionat [German], CHEMBL500826, CAS-137-40-6, CCRIS 1896, HSDB 766, Propionic acid sodium, NCGC00159468-02, EINECS 205-290-4, EPA Pesticide Chemical Code 077703, Sodium propionate, Sodium propanoate, Propionic acid sodium salt, MFCD00002759, UNII-DK6Y9P42IN, SODIUM PROPIONATE [II], SODIUM PROPIONATE [MI], INS NO.281, SODIUM PROPIONATE [FCC], HY-B1773A, INS-281, SODIUM PROPIONATE [VANDF], ANHYDROUS SODIUM PROPIONATE, CHEBI:132106, SODIUM PROPIONATE [MART.], 391O0PO49R, SODIUM PROPIONATE [USP-RS], SODIUM PROPIONATE [WHO-DD], Natriumpropionat [veterinary] (TN), Tox21_113044, Tox21_202735, AKOS003051488, AKOS015892835, SODIUM PROPIONATE [EP MONOGRAPH], NCGC00260283-01, SODIUM PROPIONATE ANHYDROUS [HSDB], ANHYDROUS SODIUM PROPIONATE [MART.], CS-0013802, E-281, NS00079169, P0512, D08440, EN300-7399958, A807253, Q420130., bioban-s;component of Prophyllin;deketon;Impedex;propisol;sodiumpropanoate;Spac;whit-pro.
Sodium Propionate is a common food additive that is industrially manufactured but also occurs in nature.
Since it is toxic to mold and some species of bacteria, it is an especially effective additive in baked goods or other products that are susceptible to spoilage.
Sodium Propionate is an effective inhibitor of the growth of certain molds and some bacteria in bakery goods.
Sodium Propionate is usually preferred in non-yeast leavened bakery products because the calcium ions’ of calcium propionate interfere with the chemical leavening agents.
In those bakery products, such as cakes, tortillas, pie fillings etc., chemically leaved agents are used (e.g. baking powder).
Sodium Propionate is easy to handle and easy to incorporate into flour.
Sodium Propionate is a safe compound when encountered at the low levels found in food.
Sodium Propionate or sodium propionate is the sodium salt of propionic acid which has the chemical formula Na(C2H5COO).
This white crystalline solid is deliquescent in moist air.
Propionate is a short chain fatty acid, which is a major part of the luminal contents of the colon.
Sodium Propionate is associated with anti-inflammatory properties.
Sodium Propionate is not only effective in food preservation but also has a range of other notable uses, each capitalizing on its unique properties.
As a preservative, it is primarily utilized in baked goods, particularly in breads, cakes, and pastries, where it helps to extend freshness by preventing mold growth and spoilage caused by yeast and bacteria.
This is particularly important for commercial bakeries, where longer shelf life can reduce waste and improve product availability.
Sodium Propionate is also used in the production of cheese, where it inhibits the development of mold on the surface of the cheese, ensuring the product remains fresh during storage and transportation.
Sodium Propionate is the sodium salt of propionic acid, a naturally occurring fatty acid found in various biological systems.
It is commonly used as a preservative in food products due to its ability to inhibit the growth of molds, bacteria, and yeast, thereby extending the shelf life of items such as baked goods, cheese, and processed meats.
As a food additive, it is typically designated by the number E281 in the European Union and is recognized as safe for consumption within regulated limits by food safety authorities worldwide.
Sodium Propionate is a white crystalline powder or granule that is highly soluble in water, which contributes to its effectiveness as a preservative.
It works by lowering the pH in the food matrix, creating an acidic environment that disrupts the growth of microbial organisms.
This antimicrobial property makes sodium propionate an essential component in the preservation of food, particularly in products that are prone to spoilage due to mold and bacterial contamination.
Beyond its use in food preservation, Sodium Propionate also finds applications in agriculture, pharmaceuticals, and cosmetics.
In agriculture, it is sometimes used as a feed additive to prevent mold growth in animal feed, particularly in silage and stored grains.
In pharmaceutical and cosmetic formulations, sodium propionate serves as a stabilizer and preservative to enhance the shelf life and safety of products.
Additionally, Sodium Propionate is used in certain industrial applications, such as in the manufacturing of plastics and coatings.
Sodium Propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder.
It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent.
Its use as a food additive is also approved in Europe. Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide.
Sodium Propionate was previously approved in Canada as an active ingredient in Amino-Cerv (used to treat inflammation or injury of the cervix).
Sodium Propionate come from its ability to dissociate into propionic acid when exposed to acidic environments.
Sodium Propionate, in turn, interferes with the growth of various microorganisms by lowering the pH in their environment, which is particularly effective against certain molds and bacteria that thrive in more neutral conditions.
Its effectiveness as a preservative is highly valued in foods that are susceptible to microbial contamination, such as dairy products, meat products, and salad dressings.
Sodium Propionate is the sodium salt form of propionic acid, a short chain fatty acid (SCFA) and food additive, with potential gastrointestinal (GI) protective activity.
Upon oral administration of sodium propionate, it converts to propionic acid which may protect the GI tract and reduce incidence and severity of GI toxicity from radiation therapy.
Sodium propionate is an organic sodium salt comprising equal numbers of sodium and propionate ions.
Sodium propionate has a role as an antifungal drug and a food preservative.
Sodium Propionate contains a propionate.
Sodium propionate (C3H5NaO2) is the sodium salt of propionic acid and is available as a white, free-owing powder.
In the food industry it is used safely as a food preservative and prevents the growth of mold and some bacteria.
In pharmacy, Sodium propionate is used in the treatment of skin fungal infections, usually in combination with calcium propionate.
Sodium propionate is used as a food preservative, as a mold inhibitor in bakery products and in insect cell culture.
Sodium propionate is also used in pharmaceuticals, cosmetics, agriculture and animal feed as preservative.
Sodium propionate acts as a food additive. Further, it inhibits the growth of lactic acid bacteria.
Sodium propionate is a salt of propionic acid, well known for its anti-mold activity.
Sodium propionate is categorized as GRAS by the U.S. FDA, and is used for various applications, globally.
The ease of availability and economic price point, coupled with the ecacy of sodium propionate, has popularized its use in multiple segments.
On the basis of application, the sodium propionate market is segmented as bakery products, meat and meat products, cheese & cheese products, pharmaceuticals, personal care and agrochemicals, and others.
In terms of volume, the bakery products segment constitutes a much larger share in the sodium propionate market than any other segment.
The increased per capita expenditure on food, owing to the rise in disposable income in multiple developing countries, is surging the demand for sodium propionate.
Customer demand is focused on the quality and longevity of the products that they buy.
Therefore, articial GRAS preservatives have become an integral part of the bakery industry.
Sodium propionate, being recognized as GRAS by the FDA, and being an economically feasible and safe option for all manufacturers, has become the go-to preservative for bakery products.
Furthermore, the demand for bakery products has been on a constant rise from matured markets such as North America and Europe as well.
Sodium propionate is an integral component of modern bakery products.
Sodium Propionate should be used in accordance with recommended guidelines to avoid any potential adverse effects.
In excessive concentrations, it may cause irritation to the skin, eyes, or respiratory tract.
However, when used properly in food and other products, sodium propionate is considered safe and effective in preventing spoilage and ensuring product quality.
Melting point: 285-286 °C (lit.)
Density: 1.51 [at 20℃]
Vapor pressure: 0 Pa at 20℃
Storage temp.: Inert atmosphere, Room Temperature
Solubility: H2O: 0.1 g/mL, clear
Form: Crystalline Powder
Color: White
Odor: At 100.00% bland
PH: 8-9.5 (10g/L, H2O, 20℃)
Biological source: Synthetic (organic)
Water Solubility: 995 g/L (20 ºC)
Sensitive: Hygroscopic
Merck: 14,8669
BRN: 3566934
Stability: Stable. Incompatible with strong oxidizing agents. Hygroscopic.
LogP: -3.23 at 25℃
Sodium propionate appears as transparent particles or crystal with specific smelly odor.
It is easily subject to deliquescence in wet air.
Sodium propionate is soluble in water, slightly soluble in alcohol.
Sodium propionate and calcium propionate are good preservatives, especially in food because very low toxicity has great advantages, bread usually calcium propionate, because bread is yeast fermentation, the use of sodium propionate can So that d increases dough, affecting yeast growth, will extend the time to face.
According to the Material Safety Data Sheet for sodium proprionate, as reported, the pure chemical can irritate the skin if handled.
However, since the general public would not come in contact with sodium propionate in its pure form, it does not likely present a risk.
The risks of consuming sodium propionate are slight if you compare it to the possibility of consuming products that have mold or bacterial contamination.
Sodium propionate is also used in the agriculture industry as a mold inhibitor for animal feed, particularly in silage (fermented green fodder) and stored grains.
By preventing mold growth, sodium propionate helps to maintain the nutritional quality of the feed, ensuring it remains safe for livestock consumption.
It is also used in feed for poultry and livestock to prevent the growth of fungi that could produce mycotoxins, harmful substances that can affect the health of animals.
In the pharmaceutical and cosmetic industries, sodium propionate functions as a preservative and stabilizer.
In pharmaceuticals, it is sometimes included in topical formulations, creams, and ointments to extend their shelf life and prevent microbial contamination.
Sodium propionate is also used in personal care products, such as lotions and shampoos, to protect against the growth of unwanted bacteria and fungi that could compromise the product’s quality.
Sodium propionate is not just restricted to food and cosmetic products; it is also employed in industrial applications.
For instance, it plays a role in the production of plastics, coatings, and adhesives.
Its inclusion in such materials helps to prevent microbial growth during production and storage.
Sodium propionate’s ability to act as a stabilizer also makes it useful in the manufacturing of certain paints and coatings, where it helps to maintain consistency and reduce the risk of degradation over time.
If sodium propionate is ingested or applied topically in an acid media, it becomes propionic acid.
Sodium propionate oxidizes fatty acids, lowers pH values, and facilitates the citric acid cycle through interaction with coenzyme A.
There has been evidence of heightened production of insulin in cows and sheep; the insulin later settles to an overall lower level.
Sodium propionate inhibits 14CO2 production from palmitate in both control and methylmalonic fibroblasts; propionic acid also inhibited ureagenesis in rat liver slices.
These findings may explain the fatty degeneration of the liver and hyperammonemia in propionic and methylmalonic acidemia.
Sodium propionate is an autosomal recessive disorder caused by a defect of propionyl–coenzyme A carboxylase.
The main clinical findings are vomiting, lethargy, hypotonia, and metabolic ketoacidosis, and early clinical onset occurs during the neonatal period in ～80% of the patients.
Sodium propionate at levels of 0.1–5.0% delays the growth of Staphylococcus aureus, Sarcina lutea, Proteus vulgaris, Lactobacillus plantarum, Torula and Saccharomyces ellipsoideus by 5 days.
The bacteriostatic action of sodium propionate can be overcome by addition of small amounts of β-alanine for Escherichia coli, but not for other organisms such as Aspergillus clavatus, Bacillus subtilis, Pseudomonas spp. and Trichophyton mentagrophytes.
Sodium propionate is believed that the inhibitory action of sodium propionate against E. coli may be due to interference with β-alanine synthesis.
Sodium propionate is usually preferred in non-yeast leavened bakery products because the calcium ions’ of calcium propionate interfere with the chemical leavening agents.
In those bakery products, such as cakes, tortillas, pie llings etc., chemically leaved agents are used (e.g. baking powder).
Sodium propionate is easy to handle and easy to incorporate into our.
Sodium propionate is a safe compound when encountered at the low levels found in food.
Sodium Propionate is the sodium salt of propionic acid that is produced during the chemical degradation of sugar.
Sodium propionate is a safe compound that is toxic to mould and some bacteria, prolonging shelf life.
Sodium propionate is a food additive and has a food label of E281. Widely used in bakery products as its concentrations are commonly low enough that you can’t taste it in products.
Sodium propanoate E281 or sodium propionate is the sodium salt of propionic acid which has the chemical formula Na(C2H5COO).
Sodium propionate is used as a food preservative and is represented by the food labeling E number E281 in Europe; it is used primarily as a mold inhibitor in bakery products.
Sodium Propionate is approved for use as a food additive in the EU.
Sodium propionate is produced by the reaction of propionic acid and sodium carbonate or sodium hydroxide.
Anhydrous sodium propionate is a polymeric structure, featuring trigonal prismatic Na+ centers bonded to six oxygen ligands provided by the carboxylates.
A layered structure is observed, with the hydrophobic ethyl groups projecting into the layered galleries.
With hydrated sodium propionate, some of these Na-carboxylate linkages are displaced by water.
Sodium propionate has been used as a supplement in transgalacto-oligosaccharides (TOS) medium for the isolation of bidobacteria.
Sodium propionate has been used as a supplement in SCFA (short-chain fatty acid) diet prepared for mice.
Sodium propionate is used as a food preservative, as a mold inhibitor in bakery products and in insect cell culture.
Sodium propionate is also used in pharmaceuticals, cosmetics, agriculture and animal feed as preservative.
Sodium propionate acts as a food additive. Further, it inhibits the growth of lactic acid bacteria.
Primary uses: Antifungal agent, antiseptic agent (topical), disinfectant, food additive, ophthalmic agent.
Sodium propionate is used primarily as a mold inhibitor in bakery products.
Sodium propionate is approved for use as a food additive in the EU, USA and Australia and New Zealand (where it is listed by its INS number 281).
Chemically synthesized sodium propionate is most commonly used as a preservative in the food industry.
Sodium propionate prevents the growth of mold and some bacteria, thereby prolonging the shelf life of packaged baked goods.
According to the Code of Federal Regulations, sodium propionate is generally recognized as safe when used as a food additive.
Sodium propionate is also used to prevent mold growth in packaged and processed cheese products.
In addition, ammonium propionate is used as an additive in animal feed to prevent overgrowth of unwanted bacteria in the stomachs of livestock.
Sodium propionate can be used as preservatives; used for anti-mould for cakes, waxberry and other mildew, Sodium propionate can be used as germicide and antiseptic.
Uses:
Primary uses: Antifungal agent, antiseptic agent (topical), disinfectant, food additive, ophthalmic agent.
It is used primarily as a mold inhibitor in bakery products.
Sodium propionate is approved for use as a food additive in the EU, USA and Australia and New Zealand (where it is listed by its INS number 281).
Sodium propionate is most commonly used as a preservative in the food industry.
It prevents the growth of mold and some bacteria, thereby prolonging the shelf life of packaged baked goods.
According to the Code of Federal Regulations, sodium propionate is generally recognized as safe when used as a food additive.
Sodium propionate is also used to prevent mold growth in packaged and processed cheese products.
Sodium propionate is used as an additive in animal feed to prevent overgrowth of unwanted bacteria in the stomachs of livestock.
It can be used as preservatives; used for anti-mould for cakes, waxberry and other mildew
It can be used as germicide and antiseptic.
Sodium propionate wet acid preservative has its antibacterial effect be affected by the environmental PH.
The minimum inhibitory concentration was 0.01% at pH 5.0 and 0.5% at pH 6.5.
In acidic medium, it has a strong inhibitory effect against various types of mold, aerobic bacillus or Gram-negative bacteria.
It has special effect in prevention the production of aflatoxin while having no effect on the yeast.
In addition, it is also used as a food preservative.
In the leather, it can be used as masking agent in order to improve the alkali resistance of leather and tanning uniformity.
In the food industry, it can be used for pastry preservation with the usage amount of 2.5g/kg (based on propionic acid, the same as below); in 3% to 5% aqueous solution, the maximal amount for soaking waxberry is 50g/kg.
Sodium propionate can also be used as feed antiseptic.
Sodium propionate is used as a food preservative and is represented by the food labeling E number E281 in Europe; it is used primarily as a mold inhibitor in bakery products.
It is approved for use as a food additive in the EU, USA and Australia and New Zealand.
Sodium propionate is an antimicrobial agent that is the sodium salt of propionic acid.
Sodium propionate occurs as colorless, transparent crystals or a gran- ular crystalline powder.
Sodium propionate is odorless or has a faint acetic–butyric acid odor, and is deliquescent.
It is prepared by neutralizing propionic acid with sodium hydroxide.
Sodium propionate is used in baked goods; nonalcoholic beverages; cheeses; confections and frostings; gelatins, puddings, and fillings; jams and jellies; meat products; and soft candy.
Sodium propionate is most widely known for its use as a preservative in the food industry.
It is primarily used in baked goods such as bread, cakes, pastries, and other bakery products.
Its antimicrobial properties help to inhibit the growth of molds, yeast, and certain bacteria that cause food spoilage.
This extends the shelf life of bakery items, reducing waste and improving storage efficiency.
Sodium propionate is especially effective in preserving bread and other baked items, preventing mold growth that can occur during storage.
Sodium propionate helps keep products fresh for longer, reducing the need for preservatives that might alter the flavor or texture.
In cheese production, sodium propionate is added to prevent the growth of mold on the surface of the cheese.
This is particularly useful in cheese varieties that are stored for long periods, ensuring that the product remains safe and consumable without spoilage or mold contamination.
Sodium propionate is also used in the preservation of processed meats, such as sausages and lunch meats.
It prevents the growth of harmful bacteria and fungi, ensuring that the meat remains safe for consumption throughout its shelf life.
In salad dressings, sauces, and condiments, sodium propionate acts as an antimicrobial agent, preventing the growth of bacteria and extending the shelf life of these products without compromising their flavor or texture.
Sodium propionate can be included in the formulation of canned and packaged food products to prevent microbial contamination, particularly in acidic foods that may be more prone to mold growth.
Sodium propionate is widely used in the agriculture sector, particularly in animal feed.
It is added to feed for livestock, poultry, and other animals to prevent mold growth in silage (fermented plant material) and stored grains.
By preventing mold, sodium propionate ensures that animal feed remains safe for consumption and free from harmful toxins that could be produced by fungi, such as mycotoxins, which can negatively impact animal health.
Silage, which is often stored in large quantities to provide winter feed for livestock, can become a breeding ground for molds and fungi.
Sodium propionate helps to preserve the quality of silage and prevents spoilage, ensuring that it remains nutritious and safe for livestock.
Similarly, stored grains, such as wheat and corn, are susceptible to mold growth, and sodium propionate helps to protect these grains during storage.
Sodium propionate is also used in poultry and livestock feed to prevent the growth of fungi that could produce harmful mycotoxins, which are toxic to animals.
By controlling mold growth, sodium propionate ensures that the feed remains nutritionally sound and safe for consumption.
Sodium propionate is used in the pharmaceutical and cosmetic industries as a preservative and stabilizer.
Its role in these industries is primarily to extend the shelf life of products by preventing the growth of microorganisms that could spoil the product or make it unsafe to use.
Sodium propionate is included in some pharmaceutical formulations, particularly in topical creams, ointments, and lotions.
Sodium propionate helps preserve the product by preventing microbial contamination during storage and use.
This is especially important for products intended for long-term use or those that are applied directly to the skin, where contamination can lead to adverse reactions.
In cosmetics, such as lotions, shampoos, deodorants, and skin care products, sodium propionate serves as an effective preservative.
Sodium propionate prevents the growth of bacteria, mold, and yeast that could spoil the product and reduce its efficacy.
It is often used in personal care products that have a longer shelf life, ensuring that the product remains safe and effective for consumers.
In addition to food, agricultural, and cosmetic uses, sodium propionate also has industrial applications where it is valued for its ability to prevent microbial contamination in manufacturing processes and improve product quality.
Sodium propionate is used in the production of plastics, coatings, and adhesives.
In these industrial applications, sodium propionate acts as an antimicrobial agent, helping to prevent mold and bacteria growth during production, storage, and transportation.
It is also used to stabilize the material and extend the shelf life of the finished product.
Sodium propionate is sometimes used in the textile industry to prevent the growth of bacteria and fungi on fabrics during production or storage.
This helps to maintain the quality of fabrics and prevents unpleasant odors or degradation caused by microbial activity.
Sodium propionate is included in certain paints and coatings to prevent microbial contamination that could lead to the spoilage of the product during storage.
Sodium propionate helps to ensure that paints, especially those used in outdoor applications, retain their stability and do not degrade due to the growth of mold or bacteria.
Sodium propionate is also used as a feed additive in veterinary medicine, particularly in veterinary nutritional products.
It is included in animal feed supplements to prevent spoilage and improve the overall quality of the product.
Sodium propionate is added to certain veterinary supplements to ensure the integrity and safety of the product during storage.
It helps to prevent microbial contamination and extend the shelf life of the supplements, ensuring that animals receive the nutritional benefits without exposure to harmful microorganisms.
Sodium propionate can also be found in some types of paints and coatings, especially those that are used in environments prone to high humidity or moisture.
It works to prevent mold growth on the surface of the paint, ensuring that the paint remains intact and aesthetically pleasing over time.
In some regions, sodium propionate is added to road salts to prevent the growth of mold and bacteria in stored salt products, especially during the winter months when road salts are heavily used to prevent ice buildup on roadways.
Safety Profile:
Sodium propionate can cause mild to moderate irritation if it comes into direct contact with the skin or eyes.
Prolonged exposure or large amounts may lead to more severe irritation, redness, or discomfort.
This is particularly true in industrial settings where workers may handle the compound in large quantities or without proper protective gear.
Direct exposure to sodium propionate, especially in powder form, can cause dryness, redness, or irritation.
It may also lead to dermatitis in individuals with sensitive skin or prolonged exposure.
If sodium propionate comes into contact with the eyes, it may cause irritation, redness, and a stinging sensation.
In more severe cases, it could lead to eye damage if not promptly washed out.
Inhalation of sodium propionate dust or vapor can irritate the respiratory system.
In industrial settings where the compound is used in powder or granular form, inhaling dust may lead to coughing, sneezing, or shortness of breath.
Prolonged or repeated exposure to airborne particles could potentially result in more serious respiratory issues, such as chronic irritation or inflammation of the airways.
When sodium propionate is handled in large quantities, especially during manufacturing or processing, fine particles may become airborne. Workers without proper respiratory protection may experience irritation in the nose, throat, or lungs.
Although sodium propionate is generally not volatile, in cases where the material is heated or processed at high temperatures, exposure to vapor could irritate the respiratory tract.
