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Sorbitan Monolaurate (E493) is a mixture of esters formed from the fatty acid lauric acid and polyols derived from sorbitol, including sorbitan and isosorbide.
As a food additive, Sorbitan Monolaurate (E493) is designated with the E number E493.
Sorbitan Monolaurate (E493) is a co-surfactant.
CAS: 1338-39-2
MF: C18H34O6
MW: 346.46
EINECS: 215-663-3
Synonyms
EmulsifierS20;radiasurf7125;Arlasel 20;emsorb2515;emulsifier(s20);Span 20 CAS NO.1338-39-2;Sorbitan Monolaurate (Span-20);Span #20 (Sorbitan monolaurate);Sorbitan monolaurate;Span 20;Sorbitan, monododecanoate;Anhydrosorbitol monolaurate;Arlacel 20;Sorbitan laurate;1338-39-2;6W9PS8B71J;INS NO.493;INS-493;1,4-Anhydro-D-glucitol, 6-dodecanoate;Sorbitan laurate [INN];E-493;(R)-2-((2R,3R,4S)-3,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl dodecanoate;SORBITAN MONODODECANOATE;[(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate;5959-89-7;Sorbitani lauras;Glycomul L;Glycomul LC;Alkamuls SML;Armotan ML;Dehymuls SML;Lonzest SML;Texnol SPT;1,4-anhydro-6-O-dodecanoyl-D-glucitol;Laurate de sorbitan;Arlacel-20;Montane 20;Alkamuls S 20;Laurato de sorbitano;Radiasurf 7125;Sorgen 90;Kemotan S 20;Sorbitan, monolaurate;Emasol L 10;Nonion LP 20R;Nonion LR 20R;Sorbon S 20;Emasol 110;Rheodol SP-L 10;Disponil SML 100;Value SP 20;Atmer 100;Emsorb 2515;Ionet S 20;Emasol L 10(F);Nissan Nonion LP 20R;L 250 (ester);Lauric acid sorbitan ester;Rheodol Super SP-L 10;Emasol Super L 10(F);SCHEMBL3833;UNII-6W9PS8B71J;CCRIS 709;Sorbitan lauric acid monoester;Sorbitani lauras [INN-Latin];CHEMBL3706389;DTXSID9027609;Sorbitan monolaurate [USAN:NF];NRF 201;SORBITAN LAURATE [MART.];SORBITAN MONOLAURATE [II];SP-L 10;Laurate de sorbitan [INN-French];SORBITAN MONOLAURATE [FCC];SORBITAN MONOLAURATE [USAN];EINECS 215-663-3;Laurato de sorbitano [INN-Spanish];SORBITAN MONOLAURATE [VANDF];HY-W129988;SORBITAN LAURATE [EP MONOGRAPH];CS-0188095;L 250;NS00081169;S0059;EC 215-663-3;8028-02-2
Sorbitan Monolaurate (E493) is a natural compound that can be isolated from the seeds of the Cucurbitaceae family.
Sorbitan Monolaurate (E493) is used in sample preparation for biocompatible polymers, as well as for detergent compositions.
Sorbitan Monolaurate (E493) has been shown to act as an absorption enhancer, which may be due to its ability to form hydrogen bonds with other molecules and its capacity to interact with sodium citrate.
Sorbitan Monolaurate (E493) also has biological properties such as the inhibition of autoimmune diseases, malonic acid production, and bacterial growth.
Sorbitan Monolaurate (E493) Chemical Properties
Boiling point: 401.18°C (rough estimate)
Density: 1.032 g/mL at 25 °C(lit.)
Vapor pressure: <1.3 hPa (20 °C)
Refractive index: n20/D 1.474(lit.)
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: Practically insoluble, but dispersible in water, miscible with alcohol.
Form: Liquid
Specific Gravity: 1.032
Color: Clear amber colour
Water Solubility: Soluble in 2-ethoxyethanol, ethanol and methanol. Not miscible or difficult to mix in water.
Merck: 14,8724
Hydrophilic-Lipophilic Balance (HLB): 8.6
LogP: 3.366 (est)
CAS DataBase Reference: 1338-39-2(CAS DataBase Reference)
EPA Substance Registry System: Sorbitan Monolaurate (E493) (1338-39-2)
Uses
Sorbitan Monolaurate (E493) is used as a lubricant and as an emulsifier.
Sorbitan Monolaurate (E493) is an emulsifier in cosmetic creams and lotions as well as a stabilizer of essential oils in water.
Sorbitan Monolaurate (E493) is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol.
Sorbitan Monolaurate (E493) has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole.
Sorbitan Monolaurate (E493) has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.
