TRISODIUM CITRATE

synonyms:
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2); 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, dihydrate; CITRATE, SODIUM, DIHYDRATE; CITRATE, TRISODIUM, 2-HYDRATE;
CITRIC ACID, TRISODIUM SALT; Citric acid, trisodium salt, dihydrate; N 1560; NATRIUMCITRAT-DIHYDRAT; Sodium citrate dihydrate; Trisodium citrate dihydrate; TRISODIUM-2-HYDROXYPROPANE-1,2,3-TRICARBOXYLATE DIHYDRATE (BP); Citric acid trisodium salt dihydrate, Sodium citrate tribasic dihydrate, Trisodium citrate dihydrate, Trisodium citrate dihydrate; 6132-04-3; Sodium citrate; tribasic dihydrate; Natriumcitrat-Dihydrat; Sodium citrate hydrate; 1,2,3-Propanetricarboxylic acid; 2-hydroxy-; trisodium salt; dihydrateUNII-B22547B95K; Citronensaeure-tri-na-salz-dihydrat; Citric acid trisodium salt dihydrateMFCD0015003Citric Acid; Trisodium Salt Dihydrate, B22547B95K; trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate; trisodium;2-hydroxypropane-1,2,3, tricarboxylate dihydrat, eNatrum citricum, ACMC-20ajao;Sodium citrate (TN), AC1Q1UPB, D05KTE, SODIUM CITRATE, ACS, AC1L2G8B, C6H9Na3O9, Soddium citrate [USP:JAN], tripotassium citrate dihydrate, KSC354K6T; Citrate-buffered saline (20X), DTXSID1049437, Sodium citrate hydrate (JP17), CHEBI:32142, CTK2F4569, Trisodium citrate dihydrate, ACS MolPort-003-928-581; NLJMYIDDQXHKNR UHFFFAOYSA-K, sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate(3:1:2), GK0137, MFCD00132371, AKOS025293920, Citric acid, trisodium salt; dihydrate, Citronensaeure, Trinatrium-Salz-Dihydrat, RTR-032650, Sodium citrate dihydrate, >=99%, FG, BP-31019, R385, Trisodium citrate dihydrate, 99% 500g; Citrate, 0.5M buffer solution, pH 2.5, Citrate, 0.5M buffer solution, pH 3.0, Citrate, 0.5M buffer solution, pH 3.5, Citrate, 0.5M buffer solution pH 4.0, Citrate; 0.5M buffer solution, pH 4.5, Citrate, 0.5M buffer solution, pH 5.0, Citrate, 0.5M buffer solution, pH 5.5, Citrate, 0.5M buffer solution, pH 6.0, Sodium citrate; tribasic dihydrate, >=98%, sODIUM CITRATE, DIHYDRATE, U.S C13249, D01781, Sodium citrate tribasic dihydrate, AR, >=99%, Sodium citrate tribasic dihydrate, LR, >=99%; paragraph signthornE(R) masculineIIi, Citric acid trisodium salt dihydrate ACS reagent, 124799-EP2287158A1, 124799-EP2295426A1, 124799-EP2295427A1, A835986; AuAEEaEyAAE paragraph signthornE(R) masculineIIi, AuAEEa EyAAENI paragraph, signthornE(R) masculineIIi, Sodium citrate tribasic dihydrate, USP, 99.0-100.5%; Sodium citrate tribasic dihydrate; ACS reagent; >=99.0% trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate, UNII-1Q73Q2JULR component; NLJMYIDDQXHKNR-UHFFFAOYSA-K; Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT) Sodium citrate tribasic dihydrate, insect cell culture tested, Sodium citrate; tribasic dihydrate, JIS special grade;>=99.0%, Sodium citrate tribasic, dihydrate, p.a., ACS reagent, 99.0%, Sodium citrate tribasic dihydrate, purum p.a., >=99.0%; (NT) Sodium citrate tribasic, dihydrate, SAJ first grade, >=99.0%, Sodium citrate tribasic dihydrate, tested according to Ph.Eur.; trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2), Trisodium citrate dihydrate, meets USP testing specifications, 2-hydroxy-1,2,3-propanetricarboxylic acid; trisodium salt dihydrate, Sodium citrate tribasic dihydrate; BioXtra, >=99.0% , Sodium citrate tribasic dihydrate, for molecular biology, >=99%; Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%, Sodium citrate, United States Pharmacopeia (USP) Reference Standard, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, sodium salt; dihydrate ; Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt; hydrate (1:3:2), Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT), Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent; >=99.0% (NT), Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%, Sodium Citrate, PharmaceuticaSecondarStandard; Certified Reference Material, 943143-17-7, Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, reag. ISO, reag., Ph. Eur., >=99.5%, Sodium citrate tribasic; dihydrate, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E331, 99-100.5% (calc. to the dried substance), Sodium citrate tribasic dihydrate; suitable for amino acid analysis, >=98% (titration), powder, NATRII CITRAS, Citratic acid, CITRIC ACID H2O, CITRIC ACID MON, CITRIC ACID MONO, CITRIC ACID BP93; SodiumCitrateBp93, SODIUM CITRATE USP, SODIUM CITRATE 2H2O, CITRIC ACID BP MONO, 106448 | tri-Sodium citrate dihydrate, C6H5Na³O7 * 2 H²O, ACS,ISO,Reag. Ph Eur; Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate, C6H5O7•2H2O•3Na, ?99%, 6132-04-3, Sodium Citrate, Dihydrate (CAS 6132-04-3), Sodium Tripolyphosphate; (STPP), 13573-18-7, Na5p3o10, Trisodium Citrate Dihydrate, Sodium Citrate (Trisodium Citrate) Chemical Formula, 6132-04-3, 200-675-3, Ph Eur,BP,JP,USP,E 331, 106446; tri-Sodium citrate dihydrate, powder EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP,E 331, C6H5Na³O7 * 2 H²O, Sodium citrate dihydrate, C6H9Na3O9, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, sodium salt, hydrate (1:3:2), 200-675-3, Citrate de sodium, hydrate (1:3:2), Citric acid trisodium salt dihydrate, ?99 %, [6132-04-3], Trisodium Citrate; Dihydrate, [Citric Acid, Trisodium Dihydrate], 6132-04-3, Citric Acid, Trisodium Dihydrate, sodium citrate dihydrate, 2-hydroxy-1,2,3-propane;tricarboxylic acid; trisodium salt dihydrate, 6132-04-3, trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, citratin citric acid, trisodium salt dihydrate, citrosodine; 2-hydroxy-1,2,3-propane, tricarboxylic acid, trisodium salt dihydrate, 2-hydroxy-1,2,3-propanetricarboxylic, trisodium salt dihydrate;, 1,2,3-propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2), sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate (3:1:2); sodium 2-hydroxy-1,2,3-propanetricarboxylate hydrate(3:1:2), sodium 2-hydroxypropane-1,2,3-tricarboxylate hydrate (3:1:2), sodium citrate dihydrate granular; sodium citrate dihydrate, powder, sodium citrate dihydrate USP/EP/JP, sodium citrate tribasic dihydrate, sodium citrate, dihydrate; trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate, trisodium citrate dihydrate, Sodium Citrate Tribasic Dihydrate, extrapure AR, 99%, Sodium citrate dihydrate; >99%, FG, 6132-04-3, HOC(COONa)(CH2COONa)2 · 2H2O, Trisodium citrate dihydrate, 6132-04-3, C6H9Na3O9, Sodium Citrate, Dihydrate, Granular, U.S.P., Multi-Compendial; TRISODIUM CITRATE DIHYDRATE, Sodium Citrate, Synonyms Citric Acid, Trisodium Salt Dihydrate, Trisodium citrate dihydrate, trisodium salt, dihydrate; Sodium citrate, tribasic dihydrate, Sodium Citrate, trisodium salt, 6132-04-3, 68-04-2, Sodium Citrate Dihydrate, 99.0 to 101.0 %, Tri-Sodium Citrate Dihydrate; Tri-Sodium Citrate Dihydrate, Certified AR for Analysis, meets analytical specification of Ph.Eur., BP, USP, Fisher Chemical, 6132-04-3, >300°C/572°F; Sodium Citrate, 6132-04-3, 6132-04-3, 612-118-5, Trisodium citrate dihydrate, trisodium citrate dihydrate, Sodium citrate hydrate; 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate, Trisodium Citrate Dihydrate, 6132-04-3, C6H5Na3O7·2H2O, 6132-04-3, ?99.0%; Trisodium 2 hydroxypropane-1,2,3-tricarboxylate dihydrate, Sodium Citrate, Sodium citrate (Trisodium citrate), 68-04-2, 1,2,3-Propanetricarboxylic acid; 2-hydroxy-, trisodium salt, Citric acid, trisodium salt, Sodium citrate, Sodium citrate anhydrous, Trisodium citrate, Citrato de trisodio, dihidrato; Citrate de trisodium, dihydrate, Trisodio citrato diidrato, Trinatriumcitraatdihydraat, Trisodium citrate dihydrate;2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, dihydrate, Trisodium citrate dihydrate, Sodium citrate dihydrat, 6132-04-3, Citnatin, Citreme, Citrosoedine, Citrosodna, Natrocitral; Trisodium citrate dihydrate, 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate, Citric acid, trisodium salt, dihydrate, 6132-04-3; Sodium citrate dihydrate, Citric acid tridosium salt dihydrate, Citric acid trisodium salt dihydrate, Sodium citrate dihydrate, Sodium citrate tribasic dihydrate; Trisodium citrate, Colorless or white solid, 6132-04-3, Sodium Citrate Dihydrate, 2-Hydroxy-1,2,3-Propanetricarboxylic Acid Trisodium Salt, Trisodium citrate dihydrate; 6132-04-3, 7758-29-4, Citrosodine, trisodium citrate, citric acid, trisodium salt, 2-hydroxy-1, 2, 3-propanetricarboxylic acid, trisodium salt, dehydrate, sodium citrate dihydrate, Trisodium Citrate Dihydrate, 6132-04-3, Trisodium citrate dihydrate, Sodium Citrate Dihydrate, 6132-04-3, 200-675-3; trisodium citrate dihydrate, Sodium citrate tribasic dihydrate, Citric acid trisodium salt dihydrate, Sodium citrate, tribasic dihydrate; Sodium 2-hydroxy-1, 2, 3-propanetricarboxylate hydrate (3:1:2), 1, 2, 3-propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2); sodium citratedihydrate, Sodium citrate hydrate, Sodium citrate, 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate,t exact copies, Citronensäure; Trinatrium-Salz-Dihydrat, trisodium citrate dihydrate, sodium citrate dihydrate, >99%, 6132-04-3, Sodium Citrate Dihydrate, 6132-04-3, Trisodium Citrate Dihydrate; 6132-04-3, 6132-04-3,Trisodium Citrate, Trisodium citrate dihydrate, SODIUM CITRATE, 6132-04-3, Sodium citrate dihydrate, 2-hydroxy-1,2,3-propanetricarboxylicacid; trisodium salt dihydrate, Sodium citrate hydrate, Trisodium citrate dihydrate, 6132-04-3, >99%, 6132-04-3, Trisodium citrate dihydrate, 6132 04 3, 200-675-3; SODIUM CITRATE, TRISODIUM CITRATE DIHYDRATE, Trisodium Citrate Dihydrate; tri; tirisodyum; tirisodıumsıtrate; sıtrat; SITRAT; SİTRAT; TİRİSODYUM; TRİSODYUM; trisodyum; TİRİSODİUMSITRAE, TIRISODIUMSITRATE; tırısodiumsitrate; trisodyumsitrat; TRİ SODYUM; tri sodyum; TRİ SODYUM SİTRAT; tri sodyum sitrat; TRİ SODYUM SİTRAT DİHİDRAT; tri sodyum sitrat dihidrat; trisodyum sitrat dihidrat; trisodyum sitrat dihidrate; TRİ SODYUM SİTRAT; tri sodyum sitrat; TRİ SODYUM SİTRAT; tri sodyum sitrat ; trisodyum sitrat ; trisodyum sitrat 

Trisodium citrate

Sodium citrate
Natriumcitrat V1.svg
Trisodium Citrate taken with my iPhone SE in my kitchen.jpg
Names
IUPAC names
Trisodium citrate
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
Other names
Citrosodine
Citric acid, trisodium salt
Sodium citrate
E331
Identifiers
CAS Number    
68-04-2 check
6132-04-3 (dihydrate) check
6858-44-2 (pentahydrate) check
3D model (JSmol)    
Interactive image
ChEMBL    
ChEMBL1355 ☒
ChemSpider    
5989 ☒
ECHA InfoCard    100.000.614 
E number    E331iii (antioxidants, ...)
PubChem CID    
6224
RTECS number    
GE8300000
UNII    
RS7A450LGA check
B22547B95K (dihydrate) check
CompTox Dashboard (EPA)    
DTXSID2026363
InChI[show]
SMILES[show]
Properties
Chemical formula    Na3C6H5O7
Molar mass    258.06 g/mol (anhydrous), 294.10 g/mol (dihydrate)
Appearance    White crystalline powder
Density    1.7 g/cm3
Melting point    > 300 °C (572 °F; 573 K) (hydrates lose water ca. 150 °C)
Boiling point    Decomposes
Solubility in water    Pentahydrate form: 92 g/100 g H2O (25 °C)[1]
Hazards
Main hazards    Irritant
Safety data sheet    External MSDS
NFPA 704 (fire diamond)    
NFPA 704 four-colored diamond
010
Lethal dose or concentration (LD, LC):
LD50 (median dose)    1548 mg/kg (intraperitoneal, rat)[2]
Related compounds
Related compounds    Monosodium citrate
Disodium citrate
Calcium citrate
Citric acid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Trisodium citrate has the chemical formula of Na3C6H5O7. It is sometimes referred to simply as "sodium citrate", though sodium citrate can refer to any of the three sodium salts of citric acid. It possesses a saline, mildly tart flavor. It is mildly basic and can be used along with citric acid to make biologically compatible buffers.

Applications
Foods
Sodium citrate is employed as a flavoring agent in certain varieties of club soda. It is common as an ingredient in bratwurst, and is also used in commercial ready-to-drink beverages and drink mixes, contributing a tart flavor. It is found in gelatin mix[clarification needed], ice cream, yogurt, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine[citation needed], amongst others.

Sodium citrate can be used as an emulsifying stabilizer when making cheese. It allows the cheese to melt without becoming greasy by stopping the fats from separating.

Buffer

Speciation diagram for a 10-millimolar solution of citric acid. The violet curve corresponds to the trisodium citrate.
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH. It is used to control acidity in some substances, such as gelatin desserts. It can be found in the milk minicontainers used with coffee machines. The compound is the product of antacids, such as Alka-Seltzer, when they are dissolved in water.[citation needed] The pH of a solution of 5 g/100 ml water at 25 °C is 7.5 – 9.0. It is added to many commercially packaged dairy products to control the PH impact of the gastrointestinal system of humans, mainly in processed products such as cheese and yogurt.

Medical uses
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining its correct concentration in 1915. It continues to be used today in blood-collection tubes and for the preservation of blood in blood banks. The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism. Recently, trisodium citrate has also been used as a locking agent in vascath and haemodialysis lines instead of heparin due to its lower risk of systemic anticoagulation.[3]

In 2003, Ööpik et al. showed the use of sodium citrate (0.5 g/kg body weight) improved running performance over 5 km by 30 seconds.[4]

Sodium citrate is used to relieve discomfort in urinary-tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. It is a major component of the WHO oral rehydration solution.

It is used as an antacid, especially prior to anaesthesia, for caesarian section procedures to reduce the risks associated with the aspiration of gastric contents.

Boiler descaling
Sodium citrate is a particularly effective agent for removal of carbonate scale from boilers without removing them from operation[5] and for cleaning automobile radiators.[6]

See also
Monosodium citrate
Disodium citrate
Citric acid
    
    Trisodium citrate dihydrate 
Trisodium citrate dihydrate has the chemical formula of Na3C6H5O7. It is sometimes referred to simply as "sodium citrate", though sodium citrate can refer to any of the three sodium salts of citric acid. Trisodium citrate dihydrate possesses a saline, mildly tart flavor. It is mildly basic and can be used along with citric acid to make biologically compatible buffers.

Applications
Foods
Trisodium citrate dihydrate is chiefly used as a food additive, usually for flavor or as a preservative. Its E number is E331. Trisodium citrate dihydrate is employed as a flavoring agent in certain varieties of club soda. It is common as an ingredient in bratwurst, and is also used in commercial ready-to-drink beverages and drink mixes, contributing a tart flavor. Trisodium citrate dihydrate is found in gelatin mix[clarification needed], ice cream, yogurt, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine[citation needed], amongst others.

Trisodium citrate dihydrate can be used as an emulsifying stabilizer when making cheese. It allows the cheese to melt without becoming greasy by stopping the fats from separating.

Medical uses
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used Trisodium citrate dihydrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining Trisodium citrate dihydrates correct concentration in 1915.Trisodium citrate dihydrate continues to be used today in blood-collection tubes and for the preservation of blood in blood banks. The Trisodium citrate dihydrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism. Recently, Trisodium citrate dihydrate has also been used as a locking agent in vascath and haemodialysis lines instead of heparin due to its lower risk of systemic anticoagulation.[3]
Trisodium citrate dihydrate is used to relieve discomfort in urinary-tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative. It is a major component of the WHO oral rehydration solution.

Trisodium citrate dihydrate is used as an antacid, especially prior to anaesthesia, for caesarian section procedures to reduce the risks associated with the aspiration of gastric contents.

Boiler descaling
Trisodium citrate dihydrate is a particularly effective agent for removal of carbonate scale from boilers without removing them from operation[5] and for cleaning automobile radiators.[6]

General information
Trisodium citrate dihydrate is a tribasic salt of citric acid. It is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation. Trisodium citrate dihydrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.

Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste. It is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).

Trisodium citrate dihydrate is a non-toxic, neutral salt with low reactivity. It is chemically stable if stored at ambient temperatures. Trisodium citrate dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.
Properties
    Dihydrate
    White
    Granular crystals or crystalline powder
    Typical, practically odourless
    Pleasantly salty
    Freely soluble in water
    Practically insoluble in ethanol (96 %)
    Non-toxic
    Low reactive
    Chemically and microbiologically stable
    Fully biodegradable
Main functions
    pH regulator
    Chelating agent
    Buffering agent
    Flavour enhancer
    Stabiliser
    Emulsifying agent
Legal aspects
In Europe, trisodium citrate is listed as generally permitted food additive (E331) and may be added to all foodstuffs, following the “quantum satis“ principle, as long as no special regulations restrict the use.

The US Food and Drug Administration (FDA) affirmed trisodium citrate as GRAS (generally recognised as safe) and permitted the use in food according to current GMP (CFR § 184.1751), without setting an upper limit.

Trisodium citrate dihydrate is a tribasic salt of citric acid. Trisodium citrate dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation. Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.Sodium citrate dihydrate is the most widely used emulsifying salt in sliced processed cheese products. It is commonly used as a buffering agent in combination with citric acid to provide precise pH control required in many food and beverage applications.Trisodium citrate is often referred to as sodium citrate, though sodium citrate can refer to any of the three sodium salts of citric acid. Sodium citrate has a saline, mildly tart flavor. It is mildly basic and can be used along with citric acid to make biologically compatible buffers. Sodium citrate is primarily used as a food additive, usually for flavor or as a preservative. In certain varieties of club soda, sodium citrate is employed as a flavoring agent. Sodium citrate is a common ingredient in Bratwurst, and is also used to contribute a tart flavor in commercial, ready-to- drink beverages and drink mixes. It is found in gelatin mix, ice-cream, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine.Sodium Citrate is also used as an emulsifier for oils in the cheesemaking process. Sodium citrate allows cheese to melt without becoming greasy. Historically, sodium phosphate was used to keep water and fat droplets mixed when cheese is melted.
 

Soy Products:
 
Bakery Flavors,Table Top Product Dairy Confectionery, Fruits, Vegetables Meat, Seafood , Cereals, Snacks Desserts, Ice Cream Ready Meals, Instant Food, Fruit Preparations, Sweet Spreads Baby Food, Infant Formula Sauces, Dressings, Seasoning The main functions of citric acid and the citrates in foods and beverages can be summarized as follows: as a flavor adjunct, to improve taste as a pH control agent, e.g., for gelation control, buffering and preservative enhancement as a chelating agent to improve the action of antioxidants and prevent spoilage of foods such as seafood Beverages, Alcoholic Beverages, Carbonated Soft Drinks, Instant Drinks, Syrups, Juice Drinks, Tea and Coffee, Sports and Energy Drinks, Waters Within this market, citric acid or its salts perform several functions. The dominant application is for flavor enhancement. Many of the lemon, lime or citrus soft drinks available today use citric acid as a way of enhancing the tangy, zesty flavor consumers associate with these tropical fruit flavors. Additionally, citric acid can help provide consistency in acidity and flavor of fruit juices or fruit cordials. If used together with sodium citrate, it is possible for citric acid to help maintain the flavor of other types of soft drinks without adding to the tanginess. Sodium citrate can also provide a cool saline taste.
 
 

Effervescent tablets and preparations:

The reaction of citric acid and bicarbonate liberates carbon dioxide, which aids the dissolution of active ingredients and improves palatability. Effervescent systems are widely used in denture-cleaning products, as well as pain relief and vitamin tablets. Pharmaceutically active substances - many are supplied as their citrate salt

pH control:

Citric acid, with sodium or potassium citrate, is an efficient buffering system used in a variety of pharmaceutical and cosmetic applications for improving stability and (where appropriate) enhancing the activity of preservatives.

Flavor: The sharp, acid taste of citric acid (which is often used to enhance fruit flavors) can help mask the unpleasant, medicinal taste of pharmaceuticals.

Antioxidant: The citrate ion is a powerful chelating agent for trace metal ions. Blood anticoagulant: The citrate ion will chelate calcium, thereby reducing the tendency for blood to clot. Diuretic - potassium citrate has diuretic properties. Clinical Nutrition Medical Devices OTC, Food Supplements Pharmaceutical Productscolor Cosmetics Deodorants, Fragrances Hair Care, Oral Care Skin Care Soap and Bath Products, Cleaners & Detergents, The major components of cleaning products are surfactants and builders. Other ingredients are added to provide a variety of functions, e.g., increasing cleaning performance for specific soils/surfaces, ensuring product stability, and supplying a unique identity to a product. Complex phosphates and sodium citrate are common sequestering builders. Builders enhance or maintain the cleaning efficiency of the surfactant. The primary function of builders is to reduce water hardness. This is done either by sequestration or chelation (holding hardness minerals in solution); by precipitation (forming an insoluble substance); or by ion exchange (trading electrically charged particles). Builders can also supply and maintain alkalinity, which assists cleaning, especially of acid soils; help keep removed soil from redepositing during washing, and emulsify oily and greasy soils. Dish Washing Industrial Cleaners, Laundry Care Surface Care. Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste. It is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).

Product Usage:

Mainly used as food additive and preservative, The anticoagulant in blood transfusions, Used to relieve discomfort in urinary tract infections, Trisodium citrate dihydrate also works as buffering agent in food and acidity regulator as antacid, As a sequestrant - to improve the quality and stability of the food p6132-04-3roducts, As a emulsifier - to stabilize processed foods like cheese. Sodium citrate material is derived from the citric acid (sodium salts). This material is available in the colorless granular form or powdery form. This is fragrance free material and generously mixed with water, but not in the alcohol. Trisodium citrate dihydrate is not contain any food allergens and it is suitable for consumption by vegans and vegetarians. Trisodium citrate dihydrate adds enjoyable flavor in food items. It is widely used as dehydrate salt, but it provides remarkable gain in dry products where long shelf life is needed to store it. Sodium Citrate Dihydrate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement. Sodium citrate. It is used as flavors, stabilizing agent, buffering agent, chelating agent, nutritional supplement of buttermilk, emulsifying agent and flavoring agent in food and beverage industry;it can be used as anti-blood clotting, apophlegmatisant and diuretics in phamaceutical industry;it can replace sodium tripolyphosphate as a non-toxic detergent additives in detergent industry;it can also be used in brewing, injection, photography drugs and electroplating etc. Contact us for more information. Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing agent. It works by neutralizing excess acid in the blood and urine. Trisodium citrate dihydrate has been indicated for the treatment of metabolic acidosis. Sodium citrate dihydrate (C6H5Na3O7•2H2O), also known as citric trisodium salt dihydrate, or trisodium citrate dehydrate is obtained from citric acid and is available in granular or powder form having a salty but pleasant taste. Sodium citrate dihydrate is odorless and freely soluble in water, marginally deliquescent in moist air, and insoluble in alcohol. Trisodium citrate dihydrate is prepared by completely neutralizing citric acid with high purity sodium hydroxide or carbonate followed by crystallization.

Global Sodium Citrate Dihydrate Market: Overview:

Trisodium citrate dihydrate is a non-toxic, neutral salt having low reactivity. Trisodium citrate dihydrate shows chemically stability when stored at ambient temperatures. Sodium citrate dihydrate is totally biodegradable and disposable with the regular waste or sewage. It is widely used in the food industry inpreservatives, and as a flavoring agent. According to the FDA Select Committee, sodium citrate are regarded as safe when used in normal quantities. In the pharmaceutical industry, it is used to resist changes in the pH. Sodium citrate dihydrate also finds its use as a buffering agent, alkalizing agent, emulsifying agent, or sequestering agent.

Global Sodium Citrate Dihydrate Market: Segmentation:

Global sodium citrate dihydrate market is segmented into types, forms, functions, applications, manufacturing methods, and region. Types of sodium citrate dehydrate can be segmented into monosodium citrate, disodium citrate, and trisodium citrate. The global sodium citrate dihydrate market can be segmented on the basis of form into granular and crystals. Functions include regulation of pH, chelating agent, buffering agent, flavor enhancer, and emulsifying agent. Application types include food and beverage industry, cleaners and detergents, industrial applications and healthcare industry. Global sodium citrate dihydrate market is also segmented on the basis of manufacturing methods. Region-wise, global sodium citrate dihydrate market is segmented into North America, Latin America, Europe, Asia-Pacific and MEA.

Global Trisodium Citrate Dihydrate Market: Region-wise Outlook:

The global sodium citrate dihydrate market is expected to witness a considerable growth in CAGR between 2015 and 2025. Owing to number of favorable conditions, the focus of the major chemical companies is gradually shifting towards the growing economies. China has graduated to become the largest base for producing chemicals worldwide in terms of capacity and output. Reason being the cost benefits over the western countries in terms of production of chemical products and a high demand within the country. Moreover, the licensing procedures are comparatively shorter and the construction costs being lower than in Europe.

Global Trisodium Citrate Dihydrate Market: Drivers & Restraints:

Seasonal factors for beverages and new detergent applications are the principal growth drivers for the global sodium citrate dihydrate market. Fluctuations in the raw materials prices hinders the steady growth of the global sodium citrate dihydrate market. Trisodium Citrate Dihydrate (TriSodium Citrate) is commonly used to improve exercise performance and as a food additive. Trisodium citrate dihydrate's naturally a strong source of antioxidants and typically used as a natural preservative. Some have also used the ingredient in beverages to increase acidity or to emulsify cheese during the aging process. This ingredient may be added to foods and beverages or smoothies and green drinks. It is a pure white powder and has no fillers or binders, additives or preservatives. Various sizes available for personal use and quantity discounts available on bulk-packed foods and food powders for commercial uses. Only the highest quality natural food and bulk ingredients are sourced through family-owned Prescribed For Life Nutrition. Thank you for shopping with us and please come again!

BENEFITS:

Promotes healthy circulation and blood flow, Balances the pH levels in the body, Odorless and tasteless, 100% food grade. We use only FDA GRAS rated ingredients (Generally Recognized as Safe) that are Non-GMO (Contains NO Genetically Modified Organisms). We have size options for individual use and in volume at wholesale pricing. Sodium citrate dihydrate with chemical formula C6H5Na3O7 - 2H2O is also known as citric trisodium salt dihydrate, or trisodium citrate dehydrate. Sodium citrate dihydrate is obtained from the reaction of citric acid, high purity sodium hydroxide or carbonate followed by crystallization. Sodium citrate dihydrate is characterised as odorless and freely soluble in water, marginally deliquescent in moist air, and insoluble in alcohol. Sodium citrate dihydrate is a non-toxic, neutral salt having low reactivity. Trisodium citrate dihydrate shows chemical stability when stored at ambient temperatures. Sodium citrate dihydrate is totally biodegradable and disposable with regular waste or sewage. Globally increasing demand from the end-use industries is expected to be the key growth driver for sodium citrate dehydrate during the period of study. Geographically, Asia-Pacific dominated trisodium citrate dihydrate market driven in terms of production and consumption driven by higher demand into major end-user industry in the region. Asia-Pacific was followed by North America and Europe as second and third largest market for sodium citrate dihydrate market. Asia Pacific is projected to have fastest growth, owing to increasing consumption into its increasing industrial base demanding higher sodium citrate dihydrate. Sodium citrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool.It will lose its crystal water at 150 °C and will be decomposed at even higher temperature. It also has slight deliquescence in wet air and has weathering property upon hot air. It is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents. Sodium citrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry. Sodium citrate has the greatest demand when being used as a food additive; As food additives, it is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives; in addition, combination between sodium citrate and citric acid can be used in a variety of jams, jelly,Sodium citrate is currently the most important citrate. Trisodium citrate dihydrate is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products. Sodium citrate has the following excellent performance: Safe and nontoxic properties; Since the basic raw material for the preparation of sodium citrate mainly comes from the food, it is absolutely safe and reliable without causing harm to human health. The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food. It is biodegradable. After subjecting to the dilution of a large amount of water, sodium citrate is partially converted into citrate, which coexists with sodium citrate in the same system. Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes. Its decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water.The ability of forming complex with metal ions. Sodium citrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, it also has a good complex-forming ability. Excellent solubility, and the solubility increases with increasing temperature of water. It has a good capability for pH adjustment and a good buffering property. Sodium citrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value. In addition, sodium citrate also has excellent retardation performance and stability. juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements. During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion; In the field of medicine, it is used for the in vitro anti-clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions; Trisodium citrate dihydrate can also used for cyanide-free electroplating industry; also used as developer for photographic industry. It can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry. Moreover, it is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application. Sodium citrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions; it is biodegradable and has a strong dispersing ability and anti- redeposition ability; Daily-applied chemical detergents use it as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent. Adding a certain amount sodium citrate to the detergent can significantly increase the cleaning ability of detergent cleaning. The large scale of application of sodium tripolyphosphate as a builder in detergents is an important discovery in synthetic detergent industry. It is non-toxic without environmental pollution; it can also be acted as a buffer for the production of cosmetics.It can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour; it also has effects on forming complex with metal ions. China rules that it can be applied to various types of food with appropriate usage according to the absolute necessity. It can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry, it is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry. It is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium; moreover, it can also be applied into pharmaceutical industry. The product can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry, it is used as anti-clotting agent, phlegm drugs and diuretics drugs. It can also be used in brewing, injection, newspaper and movies medicines.An anticoagulant also used as a biological buff. Sodium citrate is chiefly used as a food additive, usually for flavor or as a preservative. Anticoagulant for collection of blood. In photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.Sodium Citrate, Dihydrate, a conjugate base of a weak acid, can perform as a biological buffering agent because it resists changes in pH. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Trisodium Citrate Dihydrate is often used to prepare sodium citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies. Trisodium citrate dihydrate has anticoagulant activity and as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot.