Quick Search

PRODUCTS

ASCORBYL ISOSTEARATE

CAS NUMBER: 30399-84-9 

Ascorbyl Isostearate (SpecWhite®AI) is an oil-soluble derivative of ascorbic acid. 
Ascorbyl Isostearate hydrolyzes into ascorbic acid under the action of an enzyme when absorbed into skin. 
This product overcomes the deficiency of ascorbic acid, which is easily oxidated and change colors.
Ascorbyl Isostearate can inhibit the generation of melanin and accelerate the synthesis of collagen. 
Ascorbyl Isostearate also has the function of anti-oxidation.
Ascorbyl Isostearate. 
Ascorbyl Isostearate is the oil resoluble derivative of the vitamin C. 
Inhibits the generation of melanin as well as blocks up the oxidizing chain in the course of melanin generation and thus reduces the melanin. 
Ascorbyl Isostearate accelerates the synthesis of collagen and scavenges the free oxygen radicals.

Ascorbyl Isostearate inhibits the oxidation of lipid, and has the function of anti-aging. 
Possesses good resistance to acid and heat. 
Ascorbyl Isostearate can be dissolved in various oily compounds.
Ascorbyl stearate (C24H42O7) is an ester formed from ascorbic acid and stearic acid. 
In addition to its use as a source of vitamin C, Ascorbyl Isostearate is used as an antioxidant food additive in margarine (E number E305). 
The USDA limits its use to 0.02% individually or in conjunction with other antioxidants.
Ascorbyl Isostearate is an oil resoluble derivative of the Vitamin C derived from condensation reaction of Ascorbic Acid and Stearoyl Chloride, with improved solubility in various oily ingredients. 
Ascorbyl Isostearate penetrates the skin and there it is metabolized to Ascorbic Acid.
Ascorbyl stearate is a fatty acid ester.
Ascorbyl Palmitate, Ascorbyl Dipalmitate and Ascorbyl Stearate are made from vitamin C (ascorbic acid). 
Erythorbic Acid and Sodium Erythorbate are substances with structures similar to vitamin C and the sodium salt of vitamin C. 

Ascorbyl Palmitate, Ascorbyl Dipalmitate and Ascorbyl Stearate are used primarily in makeup products. 
Erythorbic Acid and Sodium Erythorbate are used primarily in hair and nail products.
Ascorbyl stearate belongs to the class of organic compounds known as fatty acid esters.
These are carboxylic ester derivatives of a fatty acid. Ascorbyl stearate is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Ascorbyl Isostearate (SpecWhite®AI) is an oil-soluble derivative of Ascorbic Acid. 
Ascorbyl Isostearate hydrolyzes into ascorbic acid under the action of an enzyme when absorbed into skin.
This product overcomes the deficiency of ascorbic acid, which is easily oxidised and changes colour. 
Ascorbyl Isostearate can inhibit the generation of melanin and accelerate the synthesis of collagen. 
Ascorbyl Isostearate also has the function of anti-oxidation
Ascorbyl stearate (Asc-S) is a synthetic ester of ascorbic acid that has been shown to significantly reduce the mutagenic effects of alkylating agents and hepatocarcinogenesis in vivo. 
We have previous demonstrated that Asc-S inhibits glioblastoma cells proliferation probably through cell cycle modulation (J Neuroncol 2001; 54:15-22). 
Here, we showed that Asc-S inhibits cell growth by induction of G2/M cell cycle arrest in human ovarian surface epithelial cancer cells. 
After Asc-S treatment, both wild type p53-expressing cell lines (Ov2008 and C13) and a mutated p53-expressing cell line (Ovcar-3) were arrested in G2/M phase of the cell cycle, suggesting that Asc-S can arrest ovarian cancer cells to G2/M checkpoint arrest via p53 dependent and independent pathways. 
The expression of p53 downstream genes, P21, GADD45 were upregulated whereas 14-3-3σ was unaffected. 
Phosphorylation of cdc2 at residue tyrosine 15 was also induced by Asc-S. Moreover, cdc25c was upregulated and redistributed as evaluated by immunofluorescence. 
This data suggest that anti-tumor activity of Asc-S is redulted from G2/M arrest in p53 dependent and independent pathways in human ovarian cancer cells.

Ascorbyl Isostearate, a Vitamin C derivative and source, is made from ascorbic acid and isostearic acid. 
Ascorbyl Isostearate can be used as an antioxidant in cosmetic products in concentrations between 0.01 and 0.2%.
Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. 
In addition to its use as a source of vitamin C, it is also used as an antioxidant food additive -E number E304-. 
Ascorbyl Isostearate is approved for use as a food additive in the EU, the U.S., Canada, Australia, and New Zealand.
Ascorbyl palmitate is known to be broken down -through the digestive process- into ascorbic acid and palmitic acid -a saturated fatty acid- before being absorbed into the bloodstream. 
The main effect of Ascorbyl Isostearate for consumers is in the protection of skin cells against UVB and UVA radiation, and with regard to the formulation, the protection of vegetable oils against oxidation.
Ascorbyl Isostearate accelerates collagen synthesis in the skin and is therefore also suitable for use in anti-aging products

Ascorbyl Isostearate reduces melanin formation in the skin and is therefore used in skin whitening products. 
By an enzymatic reaction the Ascorbyl Isostearate is hydrolysed into ascorbic acid and fatty acid. 
The released ascorbic acid prevents the oxidation step from melanin and thus has a skin-lightening effect.
Ascorbyl stearate (C₂₄H₄₂O₇) is an ester formed from ascorbic acid and stearic acid. 
In addition to its use as a source of vitamin C, it is used as an antioxidant food additive in margarine (E number E305). 
The USDA limits its use to 0.02% individually or in conjunction with other antioxidants.
Ascorbyl stearate is a fat-soluble form of Vitamin C produced from ascorbic acid and stearic acid. 
Ascorbyl Isostearate is used primarily as an antioxidant in commercial food production. 

Ascorbyl stearate is particularly poular in margarine where it prevents fats from becoming rancid.
Ascorbyl Isostearate is an oil-soluble derivative of ascorbic acid. 
Ascorbyl Isostearate hydrolyzes into ascorbic acid under the action of an enzyme when absorbed into skin. 
This product overcomes the deficiency of ascorbic acid, which is easily oxidated and change colors. 
Ascorbyl Isostearate overcomes the deficiency of ascorbic acid which is easily oxidated and change colors.
Ascorbyl Isostearate can inhibit the generation of melanin and accelerate the synthesis of collagen. 
Ascorbyl Isostearate also has the function of anti-oxidation.

Ascorbyl stearate (C24H42O7) is an ester formed from ascorbic acid and stearic acid. 
In addition to its use as a source of vitamin C, it is used as an antioxidant food additive in margarine (E number E305). 
The USDA limits its use to 0.02% individually or in conjunction with other antioxidants.
L-ascorbic acid (3-keto-L-gulofuranolactan), also called vitamin C, an indispensable component for healthy development, teeth, bones and skin; It is a carbohydrate-like chemical substance involved in metabolic functions such as absorption of iron, synthesis of collagen, maintenance of the structural strength of blood vessels, metabolism of some amino acids, and hormone synthesis and secretion by the adrenal glands.
Ascorbic acid; Ascorbyl Isostearate is a white or slightly yellow, odorless, crystalline substance that is completely soluble in water, slightly soluble in ethanol, and completely insoluble in diethyl ether solution. 
While ascorbic acid is obtained in the traditional way, sorbitol is biotransformed with the Reichstein process, which is a seven-step chemical process, while a significant progress has been made by reducing the production costs of ketogulanic acid, which is an important component in this process, with the newly developed fermentation technology.
Although ascorbic acid is often used as an acidifier for pH control purposes, it imparts an acidic taste to food products. 
Ascorbic acid used as an antioxidant in the brewing industry; It improves the shelf life of beer by preventing turbidity, acts as a preservative for maintaining the color in the meat industry, is used as a developing agent in the bakery industry, and to prevent discoloration in fruit pulp and juices. 
Apart from this, products such as butter, frozen egg products, powdered and concentrated milk, frozen potatoes, etc. can perform similar tasks.
Ascorbic acid, which has two salts, sodium ascorbate and potassium ascorbate, is used as an oxygen scavenger especially in products with headspace such as canned or bottled products. 
Sodium and calcium salts of ascorbic acid; Since it is soluble in water, it cannot protect oils from oxidation. 
For this purpose, fatty acid esters ascorbyl palmital and ascorbyl steorate are used. 
These esters are in the form of white or yellowish white crystalline powder, with a slight odor similar to citrus odor, and have an oxygen-scavenging effect in foods. 
(The numbers of the relevant food additives are as follows: E300 ascorbic acid, E301 sodium ascorbate, E302 calcium ascorbate, E303 potassium ascorbate. , E304 fatty acid esters of ascorbic acid ? ascorbyl palmitate and ascorbyl stearate)
Ascorbic acid is converted to dehydroascorbic acid by a reversible reaction by absorbing oxygen. 

This important function prevents oxidative browning in fruits and vegetables, rancidity in meat and seafood, and the development of undesirable odors in milk.
Vitamin C as an additive; It is used in vitamin preparations, beverage products and animal feeds. 
During the enrichment of foods with vitamin C, ascorbic acid already acts as an antioxidant and the vitamin value is damaged. 
In order to prevent this, the stability of the products desired to be enriched with vitamin C is achieved by eliminating free oxygen.
In fruit and vegetable processing, in an ascorbic acid solution exposed to oxidation, ascorbic acid is broken down into 3-deoxy-L-pentose and furfuralin, which are oxidation and decomposition products. 
Thus, by reacting with oxygen itself, it prevents other components in the process from being oxidized with oxygen.
The degree of this oxidation increases in the presence of oxygen, temperature rise, exposure to sunlight and ultraviolet light, the presence of heavy metals such as copper and iron, and strong acid and alkaline conditions. 
Therefore, ascorbic acid; should be stored in the dark, cold and in non-metallic containers.


FUNCTION:

-Inhibit the formation of melanin: when it is absorbed into skin, it is decomposed into ascorbic acid under enzyme, which block the oxidation process during melanin formation.
-Promote the synthesis of collagen, inhibit the oxidation of lipid, and has the action of anti-senility.
-Antioxidation and eliminate oxygen free-radical
-Good solubility: it is soluble in several oil-like compounds
-It is acid-resistant and heat resistant, and is not easily to change color

BENEFITS:

-Ascorbyl Isostearate is an oil resoluble derivative of Vitamin C derived from condensation reaction of Ascorbic Acid and Stearoyl Chloride
-improved solubility: can be dissolved in various oily ingredients with comparative function to Ascorbyl Stearate
-decreases the generation of melanin by inhibition of tyrosinase activity
-acts as an antioxidant
-decreases wrinkle progression
-improves skin lightening
-improves radiance and an even skin tone
-increases collagen production


APPLICATION:

Ascorbylisostearate is an oil Misoluble antioxidants. 
Ascorbylisostearate is very color stable and easily miscible with most of the cosmetic emollients. 
No heating, as for ascorbylpalmitate, is needed.
In cosmetic products Ascorbyl Isostearate accelerates the synthesis of collagen and is therefore an excellent additive for antiaging products.
Ascorbyl Isostearate is useful for skin whitening products, it inhibits the generation of Melanin of the skin.
By enzymatic reaction Ascorbyl Isostearate splits in the skin to Vitamin C and blocks the oxidizing step of the melanin generation.

-Ascorbyl Isostearate is an active ingredient for sophisticated cosmetic skin-care products. 
-Ascorbyl Isostearate is a stable vitamin C derivative. 
-Ascorbyl Isostearate protects the skin, promotes its development and improves its appearance.
-Ascorbyl Isostearate is cleaved enzymatically in the skin to release active vitamin C. 
-Ascorbyl Isostearate is therefore an effective antioxidant which protects the cells against damage caused by free radicals.
-Ascorbyl Isostearate counteracts skin aging in promoting collagen formation. 
-Ascorbyl Isostearate also acts on the melanine formation process to prevent hyperpigmentation and senile keratosis. 
-Ascorbyl Isostearate therefore has skin lightening properties.


PROPERTIES:

-Appearance: pale yellow liquid pale yellow liquid
-Specific Gravity: g/cm3 0,850-0,950 0,890
-Refraction (25°C): 1,450 – 1,460 1,457
-Heavy metals (Pb): < 20ppm complies
-Arsenic (As): < 2ppm


SYNONYM:

L-Ascorbyl 6-Stearate
10605-09-1
25395-66-8
L-Ascorbic acid 6-stearate
UNII-7Z1QT341US
(S)-2-((R)-3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl stearate
7Z1QT341US
L-Ascorbic acid monostearate
6-O-Stearoyl-L-ascorbic Acid
6-(Stearoyloxy)-L-ascorbic acid

  • Share !
E-NEWSLETTER