CHLORHEXIDINE GLUCONATE CHG

Chlorhexidine Gluconate CHG is a broad-spectrum antimicrobial agent widely used for antiseptic, disinfectant, and preservative applications in medical, pharmaceutical, cosmetic, and industrial formulations.
Chlorhexidine Gluconate CHG is effective against Gram-positive and Gram-negative bacteria, yeasts, and some viruses, providing rapid and long-lasting antimicrobial activity.
Chlorhexidine Gluconate CHG is valued for its high efficacy, water solubility, and residual antimicrobial effect on skin and surfaces.

CAS Number: 18472-51-0
EC Number: 242-354-0
Molecular Formula: C₂₂H₃₀Cl₂N₁₀ · 2C₆H₁₂O₇
Molecular Weight: ~897.76 g/mol

Synonyms: Chlorhexidine Gluconate CHG, Chlorhexidine Digluconate, CHG Antiseptic, Chlorhexidine Gluconate Solution, Chlorhexidine Gluconate, CHG, Chlorhexidine Gluconate Solution, Chlorhexidine Digluconate, Chlorhexidine Gluconate Salt, Chlorhexidine Digluconate Solution, Chlorhexidine Gluconate Topical Solution, Chlorhexidine Gluconate Antiseptic, Chlorhexidine Gluconate Antimicrobial, Chlorhexidine Gluconate Disinfectant, Chlorhexidine Gluconate Bactericidal Agent, Chlorhexidine Gluconate Bacteriostatic Agent, Chlorhexidine Gluconate Surgical Scrub, Chlorhexidine Gluconate Surgical Antiseptic, Chlorhexidine Gluconate Preoperative Skin Prep, Chlorhexidine Gluconate Skin Antiseptic, Chlorhexidine Gluconate Wound Antiseptic, Chlorhexidine Gluconate Healthcare Antiseptic, Chlorhexidine Gluconate Hospital Antiseptic, Chlorhexidine Gluconate Infection Control Agent, Chlorhexidine Gluconate Broad-Spectrum Antiseptic, Chlorhexidine Gluconate Broad-Spectrum Antimicrobial, Chlorhexidine Gluconate Germicide, Chlorhexidine Gluconate Biocide, Chlorhexidine Gluconate Hygiene Antiseptic, Chlorhexidine Gluconate Medical Grade, Chlorhexidine Gluconate Pharmaceutical Grade, Chlorhexidine Gluconate API, Chlorhexidine Gluconate Active Ingredient, Chlorhexidine Gluconate Active Antiseptic, Chlorhexidine Gluconate Topical Antimicrobial, Chlorhexidine Gluconate Oral Antiseptic, Chlorhexidine Gluconate Mouth Rinse Active, Chlorhexidine Gluconate Dental Antiseptic, Chlorhexidine Gluconate Gingivitis Control Agent, Chlorhexidine Gluconate Dental Plaque Control Agent, Chlorhexidine Gluconate Veterinary Antiseptic, Chlorhexidine Gluconate Livestock Antiseptic, Chlorhexidine Gluconate Hand Scrub, Chlorhexidine Gluconate Hand Wash, Chlorhexidine Gluconate Surgical Hand Scrub, Chlorhexidine Gluconate Skin Cleaner, Chlorhexidine Gluconate Antimicrobial Cleanser, Chlorhexidine Gluconate Biocidal Cleaner, Chlorhexidine Gluconate Surface Disinfectant (contextual), Chlorhexidine Gluconate Wound Care Ingredient, Chlorhexidine Gluconate Healthcare Formulation Additive, Chlorhexidine Gluconate Pharmaceutical Excipient (functional), Chlorhexidine Gluconate Personal Care Antimicrobial, Chlorhexidine Gluconate Hygiene Ingredient, Chlorhexidine Gluconate Disinfection Chemical, Chlorhexidine Gluconate Fine Chemical, Chlorhexidine Gluconate Specialty Chemical, Chlorhexidine Gluconate Industrial Biocide, Chlorhexidine Gluconate Clinical Antiseptic, Chlorhexidine Gluconate Medical Antiseptic, Chlorhexidine Gluconate Hospital Disinfectant, Chlorhexidine Gluconate Topical Preparation, Chlorhexidine Gluconate Solution Concentrate, Chlorhexidine Gluconate Dilution Solution, Chlorhexidine Gluconate Raw Material, Chlorhexidine Gluconate Bulk Ingredient, Chlorhexidine Gluconate Process Chemical, Chlorhexidine Gluconate Controlled-Release Agent (pharma context), Chlorhexidine Gluconate Anti-Infective Agent, Chlorhexidine Gluconate Infection Prevention Agent

APPLICATIONS

Chlorhexidine Gluconate CHG is used in medical antiseptics.
Chlorhexidine Gluconate CHG is applied for skin disinfection before surgery and injections.
Chlorhexidine Gluconate CHG provides prolonged antimicrobial protection on skin.

Chlorhexidine Gluconate CHG is used in pharmaceutical products.
Chlorhexidine Gluconate CHG is formulated into topical solutions, gels, and sprays.
Chlorhexidine Gluconate CHG supports infection control in healthcare settings.

Chlorhexidine Gluconate CHG is widely used in oral care products.
Chlorhexidine Gluconate CHG is applied in mouthwashes for plaque and gingivitis control.
Chlorhexidine Gluconate CHG reduces oral bacterial load effectively.

Chlorhexidine Gluconate CHG is incorporated into personal care formulations.
Chlorhexidine Gluconate CHG functions as a preservative and antimicrobial booster.
Chlorhexidine Gluconate CHG supports product safety and shelf life.

Chlorhexidine Gluconate CHG is used in industrial and veterinary disinfectants.
Chlorhexidine Gluconate CHG ensures hygiene in equipment and surface sanitation.
Chlorhexidine Gluconate CHG maintains efficacy over a wide pH range.

Chlorhexidine Gluconate CHG is used as a broad-spectrum antiseptic in healthcare settings.
Chlorhexidine Gluconate CHG reduces microbial load on skin surfaces.
Chlorhexidine Gluconate CHG is used in hospital infection control protocols.
Chlorhexidine Gluconate CHG helps prevent healthcare-associated infections.

Chlorhexidine Gluconate CHG is used in preoperative skin disinfection.
Chlorhexidine Gluconate CHG lowers the risk of surgical site infections.

Chlorhexidine Gluconate CHG is used in wound cleansing solutions.
Chlorhexidine Gluconate CHG supports infection control in acute and chronic wounds.

Chlorhexidine Gluconate CHG is used in burn care preparations.
Chlorhexidine Gluconate CHG reduces microbial growth on damaged skin.

Chlorhexidine Gluconate CHG is used in hand antiseptic products.
Chlorhexidine Gluconate CHG provides long-lasting antimicrobial protection.
Chlorhexidine Gluconate CHG is used in intensive care unit hygiene.
Chlorhexidine Gluconate CHG supports strict infection prevention measures.

Chlorhexidine Gluconate CHG is used in catheter site antiseptics.
Chlorhexidine Gluconate CHG reduces microbial colonization on medical devices.

Chlorhexidine Gluconate CHG is used in oral hygiene formulations.
Chlorhexidine Gluconate CHG reduces dental plaque accumulation.
Chlorhexidine Gluconate CHG is used in medicated mouthwashes.

Chlorhexidine Gluconate CHG supports management of gingivitis.
Chlorhexidine Gluconate CHG is used in periodontal treatments.
Chlorhexidine Gluconate CHG controls oral bacterial populations.

Chlorhexidine Gluconate CHG is used in dental surgery aftercare.
Chlorhexidine Gluconate CHG reduces postoperative infection risk.

Chlorhexidine Gluconate CHG is used in veterinary antiseptic products.
Chlorhexidine Gluconate CHG treats bacterial skin infections in animals.

Chlorhexidine Gluconate CHG is used in animal wound care solutions.
Chlorhexidine Gluconate CHG supports hygienic healing processes.

Chlorhexidine Gluconate CHG is used in pharmaceutical antiseptic formulations.
Chlorhexidine Gluconate CHG functions as an active antimicrobial ingredient.
Chlorhexidine Gluconate CHG is used in cosmetic hygiene products.
Chlorhexidine Gluconate CHG helps control microbial contamination.

Chlorhexidine Gluconate CHG is used in personal care cleansing products.
Chlorhexidine Gluconate CHG enhances microbial safety of formulations.

Chlorhexidine Gluconate CHG is used in disinfectant sprays and wipes.
Chlorhexidine Gluconate CHG provides residual antimicrobial activity on treated surfaces.

Chlorhexidine Gluconate CHG is used in laboratory disinfection routines.
Chlorhexidine Gluconate CHG supports aseptic working environments.

Chlorhexidine Gluconate CHG is used in surgical hand scrub formulations.
Chlorhexidine Gluconate CHG reduces transient and resident skin flora.

Chlorhexidine Gluconate CHG is used in pre-injection skin antisepsis.
Chlorhexidine Gluconate CHG minimizes injection-related infections.
Chlorhexidine Gluconate CHG is used in central line insertion kits.
Chlorhexidine Gluconate CHG lowers catheter-related bloodstream infections.

Chlorhexidine Gluconate CHG is used in patient bathing solutions.
Chlorhexidine Gluconate CHG reduces colonization by multidrug-resistant organisms.

Chlorhexidine Gluconate CHG is used in ICU daily hygiene protocols.
Chlorhexidine Gluconate CHG supports infection prevention in critical care.

Chlorhexidine Gluconate CHG is used in neonatal skin care products.
Chlorhexidine Gluconate CHG provides controlled antimicrobial protection when properly diluted.

Chlorhexidine Gluconate CHG is used in obstetric antiseptic preparations.
Chlorhexidine Gluconate CHG reduces infection risk during childbirth procedures.

Chlorhexidine Gluconate CHG is used in gynecological cleansing products.
Chlorhexidine Gluconate CHG supports vaginal hygiene under medical guidance.

Chlorhexidine Gluconate CHG is used in urological antiseptic solutions.
Chlorhexidine Gluconate CHG reduces microbial contamination during procedures.
Chlorhexidine Gluconate CHG is used in dialysis access site care.
Chlorhexidine Gluconate CHG minimizes infection risk in dialysis patients.

Chlorhexidine Gluconate CHG is used in home healthcare antiseptic products.
Chlorhexidine Gluconate CHG supports infection control outside clinical settings.

Chlorhexidine Gluconate CHG is used in first aid antiseptic sprays.
Chlorhexidine Gluconate CHG helps prevent infection in minor injuries.

Chlorhexidine Gluconate CHG is used in emergency medical services.
Chlorhexidine Gluconate CHG provides rapid antimicrobial action in field conditions.

Chlorhexidine Gluconate CHG is used in antiseptic impregnated wipes.
Chlorhexidine Gluconate CHG maintains surface hygiene during patient care.

Chlorhexidine Gluconate CHG is used in hospital bed bathing wipes.
Chlorhexidine Gluconate CHG reduces skin colonization without rinsing.
Chlorhexidine Gluconate CHG is used in preoperative shower products.
Chlorhexidine Gluconate CHG reduces microbial load before surgery.

Chlorhexidine Gluconate CHG is used in surgical drape impregnation.
Chlorhexidine Gluconate CHG enhances antimicrobial barrier properties.

Chlorhexidine Gluconate CHG is used in medical glove coatings.
Chlorhexidine Gluconate CHG improves infection control during procedures.

Chlorhexidine Gluconate CHG is used in antiseptic lubricating gels.
Chlorhexidine Gluconate CHG reduces infection risk during catheter insertion.
Chlorhexidine Gluconate CHG is used in ENT antiseptic preparations.
Chlorhexidine Gluconate CHG helps manage microbial contamination in ear care.

Chlorhexidine Gluconate CHG is used in ophthalmic surface disinfection.
Chlorhexidine Gluconate CHG supports hygiene of periocular skin.

Chlorhexidine Gluconate CHG is used in podiatric antiseptic products.
Chlorhexidine Gluconate CHG helps manage foot infections and hygiene.

Chlorhexidine Gluconate CHG is used in cosmetic manufacturing sanitation.
Chlorhexidine Gluconate CHG controls microbial contamination during production.

Chlorhexidine Gluconate CHG is used in pharmaceutical equipment sanitation.
Chlorhexidine Gluconate CHG supports clean manufacturing environments.

Chlorhexidine Gluconate CHG is used in laboratory animal care.
Chlorhexidine Gluconate CHG reduces pathogen transmission in research facilities.

Chlorhexidine Gluconate CHG is used in livestock hygiene programs.
Chlorhexidine Gluconate CHG supports skin and wound sanitation in animals.

Chlorhexidine Gluconate CHG is used in teat disinfection solutions.
Chlorhexidine Gluconate CHG reduces mastitis-related bacterial contamination.
Chlorhexidine Gluconate CHG is used in poultry biosecurity measures.
Chlorhexidine Gluconate CHG helps control surface pathogens in farms.

Chlorhexidine Gluconate CHG is used in aquaculture hygiene systems.
Chlorhexidine Gluconate CHG reduces microbial load on equipment and tanks.

Chlorhexidine Gluconate CHG is used in cleanroom sanitation protocols.
Chlorhexidine Gluconate CHG supports controlled microbial environments.

Chlorhexidine Gluconate CHG is used in cosmetic packaging sanitation.
Chlorhexidine Gluconate CHG improves product safety during filling operations.

Chlorhexidine Gluconate CHG is used in personal protective equipment sanitation.
Chlorhexidine Gluconate CHG reduces contamination of reusable gear.

DESCRIPTION

Chlorhexidine Gluconate CHG is typically supplied as a clear to pale yellow aqueous solution.
Chlorhexidine Gluconate CHG has a faint characteristic odor.
Chlorhexidine Gluconate CHG is a salt of chlorhexidine and gluconic acid.

Chlorhexidine Gluconate CHG is highly soluble in water.
Chlorhexidine Gluconate CHG exhibits cationic character, allowing strong binding to skin and tissues.
Chlorhexidine Gluconate CHG provides sustained antimicrobial activity after application.

Chlorhexidine Gluconate CHG acts by disrupting microbial cell membranes.
Chlorhexidine Gluconate CHG causes leakage of intracellular components leading to cell death.
Chlorhexidine Gluconate CHG shows low systemic absorption when applied topically.

Chlorhexidine Gluconate CHG is stable under recommended storage conditions.
Chlorhexidine Gluconate CHG is incompatible with anionic surfactants and soaps.
Chlorhexidine Gluconate CHG should be formulated carefully to preserve activity.

Chlorhexidine Gluconate CHG is a water-soluble gluconate salt of chlorhexidine.
Chlorhexidine Gluconate CHG appears as a clear to pale yellow liquid.
Chlorhexidine Gluconate CHG exhibits strong antimicrobial activity.

Chlorhexidine Gluconate CHG is effective against Gram-positive bacteria.
Chlorhexidine Gluconate CHG is effective against Gram-negative bacteria.
Chlorhexidine Gluconate CHG shows limited activity against spores and some viruses.

Chlorhexidine Gluconate CHG acts by disrupting microbial cell membranes.
Chlorhexidine Gluconate CHG causes leakage of intracellular components.
Chlorhexidine Gluconate CHG binds to skin and mucous membranes.

Chlorhexidine Gluconate CHG provides prolonged residual antimicrobial action.
Chlorhexidine Gluconate CHG demonstrates good stability in aqueous formulations.
Chlorhexidine Gluconate CHG is widely used in medical, dental, and veterinary fields.

Chlorhexidine Gluconate CHG should be stored in tightly closed containers.
Chlorhexidine Gluconate CHG should be protected from light and contamination.
Chlorhexidine Gluconate CHG is valued for its effectiveness, persistence, and broad antimicrobial performance.

PROPERTIES

Chemical Formula: C₂₂H₃₀Cl₂N₁₀ · 2C₆H₁₂O₇
Molecular Weight: ~897.76 g/mol
Appearance: Clear to pale yellow liquid (aqueous solution)
Odor: Faint characteristic odor
Physical State: Typically supplied as 20% or lower aqueous solution
Density: ~1.06 g/cm³ at 25°C (20% solution)
Solubility in Water: Completely soluble
Solubility in Organic Solvents: Slightly soluble in alcohols; insoluble in nonpolar solvents
pH (5% solution): ~5.0–7.0
Ionic Character: Cationic
Melting Point: Not applicable (aqueous salt; decomposes before melting)
Thermal Stability: Stable under normal storage temperatures
Antimicrobial Spectrum: Broad-spectrum antibacterial and antifungal activity
Residual Activity: High; binds to skin and mucous membranes
Chemical Stability: Stable in neutral to mildly acidic conditions
Incompatibilities: Anionic surfactants, soaps, and strong oxidizing agents
Storage Stability: Good when protected from light and contamination

FIRST AID

Inhalation:
Move to fresh air if mist is inhaled.
Seek medical attention if irritation persists.

Skin Contact:
Generally safe for topical use.
Rinse with water if irritation occurs.

Eye Contact:
Rinse immediately with plenty of water for at least 15 minutes.
Seek medical attention promptly.

Ingestion:
Rinse mouth with water.
Do not induce vomiting.
Seek medical attention immediately.

Note to Physicians:
Treat symptomatically; supportive care as required.

HANDLING AND STORAGE

Handling:
Use protective gloves and eye protection during handling.
Avoid contact with eyes and incompatible materials.

Avoidance:
Avoid mixing with anionic surfactants or soaps.
Avoid contamination of product during use.

Spill Procedures:
Absorb with inert material and clean with water.
Dispose of according to local regulations.

Storage:
Store in tightly closed, properly labeled containers.
Keep in a cool, dry, well-ventilated area.
Protect from direct sunlight and freezing.