CYCLAMATE

CAS NO:139-05-9
EC NO:205-348-9

Cyclamate is an artificial sweetener. 
Cyclamate is 30–50 times sweeter than sucrose (table sugar), making it the least potent of the commercially used artificial sweeteners. 
Cyclamate is often used with other artificial sweeteners, especially saccharin; the mixture of 10 parts cyclamate to 1 part saccharin is common and masks the off-tastes of both sweeteners.
Cyclamate is less expensive than most sweeteners, including sucralose, and is stable under heating. Safety concerns led to it being banned in a few countries, though the European Union considers it safe.

Properties:
Chemical formula:C6H12NNaO3S
Molar mass:201.22 g·mol−1

Chemistry
Cyclamate is the sodium or calcium salt of cyclamic acid (cyclohexanesulfamic acid), which itself is prepared by reacting freebase cyclohexylamine with either sulfamic acid or sulfur trioxide.

Prior to 1973, Abbott Laboratories produced sodium cyclamate (Sucaryl) by a mixture of ingredients including the addition of pure sodium (flakes or rods suspended in kerosene) with cyclohexylamine, chilled and filtered through a high speed centrifugal separator, dried, granulated and micro-pulverised for powder or tablet usage.

Cyclamate, odourless white crystalline powder that is used as a nonnutritive sweetener. The name usually denotes either calcium cyclamate or sodium cyclamate, both of which are salts of cyclohexylsulfamic acid (C6H11NHSO3H). These compounds are stable to heat and are readily soluble in water. 
Cyclamates have a very sweet taste, with about 30 times the sweetening power of sucrose. They are used as sweeteners in baked goods, confections, desserts, soft drinks, preserves, and salad dressings. They are often combined with saccharin to produce a synergistic sweetening effect.

Physicochemical Information:
pH value:5.5 - 7.5 (100 g/l, H₂O, 20 °C)
Bulk density:600 - 700 kg/m3
Solubility:200 g/l

Chemical Properties
Cyclamate occurs as white, odorless or almost odorless crystals, or as a crystalline powder with an intensely sweet taste.

Chemical Properties
White powder

Production Methods
Cyclamates are prepared by the sulfonation of cyclohexylamine in the presence of a base. Commercially, the sulfonation can involve sulfamic acid, a sulfate salt, or sulfur trioxide. Tertiary bases such as triethylamine or trimethylamine may be used as the condensing agent. The amine salts of cyclamate that are produced are converted to the sodium, calcium, potassium, or magnesium salt by treatment with the appropriate metal oxide.

Cyclamate is an artificial sweetener and is 30 times as saccharose's. 
Cyclamate is widely used in pickles, seasoning sauce, cakes, biscuits, bread, ice cream, frozen sucker, popsicles, drinks and so on, with a maximum amount of 0.65g/kg. Secondly, it is used in confect, with a maximum amount of 1.0g/kg. Thirdly, it is used in orange peel, preserved plum, dried arbutus and so on, with the largest amount of 8.0g/kg. 
Cyclamate is also used in cosmetics and pharmaceutical industry.

About Cyclamate
Helpful information
Cyclamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.

Cyclamate is used at industrial sites.

Consumer Uses
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which Cyclamate is most likely to be released to the environment.

Article service life
ECHA has no public registered data on the routes by which Cyclamate is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the types of manufacture using Cyclamate. ECHA has no public registered data on the routes by which Cyclamate is most likely to be released to the environment.

Formulation or re-packing
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which Cyclamate is most likely to be released to the environment.

Uses at industrial sites
Cyclamate is used in the following products: fillers, putties, plasters, modelling clay and lubricants and greases.
ECHA has no public registered data on the types of manufacture using Cyclamate. Release to the environment of Cyclamate can occur from industrial use: in the production of articles.

Manufacture
ECHA has no public registered data on the routes by which Cyclamate is most likely to be released to the environment.

Cyclamate is a new non-nutrition sweetener with delicious flavor ,which covers bitter taste.The sweet taste slowly but keeps for long time.
Cyclamate is no harm for human being and safe than sugar saccharin.
Cyclamate is kind of healthy food additives with sugar-free and low calorie.
Cyclamate is 30~50 times sweeter than sucrose without the effect of souring and fermentation like sucrose. 
Sweetness comes slowly, but keep long time.

Cyclamate is high sweetness,50 times than sugar ,harmless to health and stable.
Cyclamate does not absorb water from air.Resistant to heat,acid and alkaline.
Cyclamate is widely used in food production indusry ,daily living commodity,such as soft drink,seasoning sauce,cake,biscuits,ice cream,beverage and so on.

Cyclamate appears as odorless or almost odorless white crystals or crystalline powder. Intensely sweet taste, even in dilute solution. pH (10% solution in water): 5.5-7.5. Used as a non-nutritive sweetener.

Cyclamate is an organic molecular entity.
Salts and esters of cyclamic acid.

Cyclamate or cyclamates is the everyday name for the sweeteners cyclamic acid, calcium and cyclamate sodium which share the e‑number E 952. 
Cyclamates are viewed as non-energizing sweeteners. They are about 30 times sweeter than sugar and are often combined with saccharin (E 954).

To get a good sugar-like taste, manufacturers usually mix 1 part saccharin with 10 parts cyclamates (1:10). Of all the artificial sweeteners, this is the mixture that best mimics sugar dissolved in water.

Cyclamate is the solid form of the artificial sweetener cyclamate. Because of potential health concerns, cyclamate is currently banned by the U.S. Food and Drug Administration for consumption by humans. However, cyclamate is currently being considered for reapproval due to its safe use in other countries. Artificial sweeteners allow you to lower sugar in your diet, however, they should all be consumed in moderation.

Cyclamate is a synthetic artificial sweetener that is 30 to 50 times sweeter than sugar the least sweet of all artificial sweeteners. 
Cyclamate does leave an aftertaste, although less so than other artificial sweeteners such as saccharin. 
Cyclamate is stable under heating and is commonly used in baked goods where other artificial sweeteners cannot be used. 
Cyclamate is also combined with other sweeteners, particularly saccharin, to improve palatability.

Cyclamate is a white, crystal solid or powder with almost no odor and a very sweet taste.
Cyclamates sweetening power is about 30 times that of table sugar, the standard against which artificial sweeteners are measured. 

Cyclamate, discovered in 1937, is a non-caloric sweetener approximately 30 times as sweet as sucrose. Like other low-calorie sweeteners, cyclamate is of benefit to those seeking to control weight, manage diabetes, or help prevent tooth decay. 
Cyclamates, whether in the form of sodium cyclamate or calcium cyclamate, are stable and soluble. 
Cyclamate is used as a tabletop sweetener, in diet beverages, and in other low-calorie foods. In addition, cyclamate is useful as a flavor enhancer. 
Cyclamate’s heat stability, high order of sweetness and other technological advantages also make it a good flavoring agent for many pharmaceutical preparations and toiletries.

Benefits
When cyclamate is combined with other low-calorie sweeteners, a synergistic effect results–that is the two sweeteners in combination taste sweeter than what normally would be expected from the sum of the individual sweeteners. Additionally, the aftertaste sometimes associated with the use of a single sweetener can be masked by combining sweetening agents. For example, the mixture of 10 parts cyclamate to one part saccharin is a combination which was widely used in foods and beverages during the 1960s. 
Cyclamate can serve as an excellent complement to other low-calorie sweeteners which are available and, particularly because of its unique synergistic sweetening properties, makes possible a wider variety of good-tasting low-calorie products. 
Cyclamate is stable in heat and cold and has good shelf life. Its solubility in liquids enables use in beverages.

Cyclamate can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry. 
Cyclamate is the sodium salt of cyclamic acid. 
Cyclamate can be used as a sugar substitute in soft drinks, liquors, seasonings, cakes, biscuits, bread, and ice cream. 
Cyclamate appears as a white powder that is approximately 50 times the sweetness of table sugar.

Cyclamate is also combined with other low calorie sweeteners – particularly saccharin, aspartame and acesulfame-K – in food and beverage.

Cyclamate has found a variety of applications in beverage, food, confectionery, bakery, pharmaceutical, health and personal care industry. In some cases, it can also be blended with other artificial sweeteners to produce some special or favorable combinations of taste and sweetness.

Cyclamate used in Tabletop sweeteners, processed fruits like fruit juice, jam and canned fruit; chewing gum and confections, salad dressings, gelatin desserts, jellies, jams and toppings, candies, bakery products and dairy products; barbecued food, pasta, rice, breakfast cereal and other condiments.

Food industry : barbecued food, pasta, rice, breakfast cereal, canned food, vinegar sauce, ketchup and other condiments
Confectionery, bakery, desert and dairy products

Cyclamate is an artificial sweetener. 
Cyclamate is 30–50 times sweeter than sugar.
Cyclamate is often used synergistically with other artificial sweeteners, especially saccharin; the mixture of 10 parts cyclamate to 1 part saccharin is common and masks the off-tastes of both sweeteners. 
Cyclamate is less expensive than most sweeteners, including sucralose, and is stable under heating.

Cyclamate is a sugar substitute widely used as sweetener in food and beverage. As a sweetener, Cyclamate can be used in a wide variety of industries including: food production, beverage, cosmetics, and various other industries.

Cyclamate in Food Production
Cyclamate is widely used as sweetener in food production.
As sweetener: in cakes, baked foods, candied fruits and Pickles to improve sweetness.

Cyclamate in Beverage
Cyclamate is widely used as sweetener in beverage.
As sweetener: in soft drinks, juices and icecreams to improve sweetness.

Cyclamate in Pharmaceutical
Not enough is known about application of Cyclamate in Pharmaceutical.

Cyclamate in Cosmetics
Cyclamate is widely used as sweeteness in Cosmetics.
As sweeteness: in lipsticks to improve sweetness.

IUPAC names
Natriumcyclohexylamidosulfat
Sodium cyclamate
sodium cyclamate
sodium cyclohexylsulfamate
Sodium N-Cyclohexylsulfamate
sodium N-cyclohexylsulfamate
Sodium N-cyclohexylsulphamate.

SYNONYMS:
Sodium cyclamate [INN] [Wiki]
139-05-9 [RN]
168
1I6F42RME1
205-348-9 [EINECS]
61373-78-2 [RN]
aminocyclohexylsulfonic acid, sodium salt
ciclamato de sodio [Spanish] [INN]
cyclamate de sodium [French] [INN]
Cyclamate de sodium
Cyclamic acid sodium salt
Cyclohexanesulfamic acid sodium salt
Cyclohexanesulfamic acid, monosodium salt
Cyclohexylsulfamate de sodium [French] [ACD/IUPAC Name]
Cyclohexylsulfamic Acid Sodium Salt
GV7350000
MFCD00003827 [MDL number]
Monosodium cyclohexylsulfamate
natrii cyclamas [Latin] [INN]
Natriumcyclohexylsulfamat [German] [ACD/IUPAC Name]
N-Cyclohexylsulfamic acid sodium salt
SODIUM (SULFONATOAMINO)CYCLOHEXANE
Sodium cyclohexanesulfamate
Sodium cyclohexylsulfamate [ACD/IUPAC Name]
Sodium N-Cyclohexylsulfamate
Sucaryl Acid Sodium Salt
Sulfamic acid, cyclohexyl-, monosodium salt
Sulfamic acid, N-cyclohexyl-, sodium salt (1:1) [ACD/Index Name]
натрия цикламат [Russian] [INN]
سيكلامات صوديوم [Arabic] [INN]
环拉酸钠 [Chinese] [INN]
[139-05-9]