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DISODIUM 5'-RIBONUCLEOTIDE

CAS NUMBER: 4691-65-0

EC NUMBER: 225-146-4

MOLECULAR FORMULA: C10H11N4Na2O8P

MOLECULAR WEIGHT: 392.17

IUPAC NAME: disodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate


Disodium 5'-Ribonucleotide, E number E635, is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. 
Disodium 5'-Ribonucleotide is a mixture of disodium inosinate (IMP) and Disodium 5'-Ribonucleotide (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added monosodium glutamate (MSG). 

Disodium 5'-Ribonucleotide, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). 
Disodium 5'-Ribonucleotide is a food additive with the E number E627. 
Disodium 5'-Ribonucleotide is commonly used in conjunction with glutamic acid. 

As Disodium 5'-Ribonucleotide is a fairly expensive additive, it is not used independently of glutamic acid; if Disodium 5'-Ribonucleotide is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. 

Disodium 5'-Ribonucleotide is produced from dried seaweed and is often added to instant noodles, potato chips.
Disodium 5'-Ribonucleotide may be safely used as a flavor enhancer in foods, at a level not in excess of that reasonably required to produce the intended effect.

Disodium 5'-Ribonucleotide is used as a flavor enhancer, in synergy with monosodium glutamate (MSG) to provide the umami taste. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with Disodium 5'-Ribonucleotide; the combination is known as disodium 5'-ribonucleotides.
Disodium 5'-Ribonucleotide is an organic sodium salt that is the disodium salt of GMP. 

Disodium 5'-Ribonucleotide has a role as a flavouring agent. 
Disodium 5'-Ribonucleotide contains a guanosine 5'-monophosphate(2-).

Disodium 5'-Ribonucleotide is primarily used in: 
-flavored noodles 

-snack foods 

-chips

-crackers 

-sauces

-fast foods

Disodium 5'-Ribonucleotide is produced by combining the sodium salts of the natural compounds guanylic acid (E626) and inosinic acid (E630).
Disodium 5'-Ribonucleotide is a mixture composed of 98% monosodium glutamate and 2% E635 has four times the flavor enhancing power of monosodium glutamate (MSG) alone.

Disodium 5'-Ribonucleotide, E number E635, is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. 
Disodium 5'-Ribonucleotide is a mixture of disodium inosinate (IMP) and Disodium 5'-Ribonucleotide (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added monosodium glutamate (MSG). 

Disodium 5'-Ribonucleotide is primarily used in flavored noodles, snack foods, chips, crackers, sauces and fast foods. It is produced by combining the sodium salts of the natural compounds guanylic acid (E626) and inosinic acid (E630).
Disodium 5'-Ribonucleotide, E number E635, is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. 

Disodium 5'-Ribonucleotide is a mixture of disodium inosinate (IMP) and Disodium 5'-Ribonucleotide (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added monosodium glutamate (MSG). 
Disodium 5'-Ribonucleotide is primarily used in flavored noodles, snack foods, chips, crackers, sauces and fast foods. 

Disodium 5'-Ribonucleotide is produced by combining the sodium salts of the natural compounds guanylic acid (E626) and inosinic acid (E630). 
Disodium 5'-Ribonucleotide is a mixture composed of 98% monosodium glutamate and 2% E635 has four times the flavor enhancing power of monosodium glutamate (MSG) alone.

Disodium 5'-Ribonucleotide (I + G) is one of the most popular food additives and ingredients in most countries.
Disodium 5'-Ribonucleotide is a premium line of nucleotides with the Ajinomoto touch which unlocks the taste characteristics of foods synergy with glutamates and other flavor enhancers nucleotides have.

Disodium 5'-Ribonucleotide, also known as I+G, is a flavor enhancer made of disodium inosinate and Disodium 5'-Ribonucleotide with the ratio 1:1. 
Disodium 5'-Ribonucleotide Consist if white or off-white crustals or Powder.

Disodium 5'-Ribonucleotide is a food additive manufactured through chemical synthesis of sodium salt of guanylic acid and inosinic acid, available as White to light yellow crystalline powder. 
Disodium 5'-Ribonucleotides is widely used as flavour enhancer as it can increase flavour significantly when using together with monosodium glutamate. 

Disodium 5'-Ribonucleotide is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E635. 
Disodium 5'-Ribonucleotide is a type of flavour enhancers
Disodium 5'-Ribonucleotide is essentially a mixture of disodium inosine-5'-monophosphate and disodium guanosine-5'-monophosphate

Multiply effect in delicate flavor. 
When Disodium 5'-Ribonucleotide is used with sodium glutamate, Disodium 5'-Ribonucleotide can form multiplied improving for delicate flavor so as to reduce the product cost. 
Enhance and improve food flavor; enhance the naturally delicious, strong, fragrant and sweet flavor. 

Disodium 5'-Ribonucleotide can make meat more delicious; when it mixed with monosodium glutamate and added into the meat, it can improve the meat original taste and enhance the meat delicate flavor, so that it can reduce meat consumption and reduce cost. 
Restrain too salty, bitter, sour and other objectionable flavor and reduce foreign taste (amino acid taste or flour taste)
Disodium 5'-Ribonucleotide is with good solubleness and stability in product.

APPLICATIONS:

Disodium 5'-Ribonucleotide is a new geneartonal nucleotide food taste agent. 
Disodium 5'-Ribonucleotide is prepared through the IMP (DISODIUMINOSINE5’—MONOPHOSPHATE) and GMP (DISODIUM GUANOSINE5’—MONOPHOSPHATE) are mixed with proportion of 1:1. 
Disodium 5'-Ribonucleotide can be directly added in food and act taste improving effect. 

Disodium 5'-Ribonucleotide is a kind of economic and best effective taste enhancer, and is also the main flavoring component in seasoning packet of instant noodles, seasoning, such as chicken extract, chicken powder, flavor enhancing soybean sauce and others. 
When mixing with sodium glutamate (monosodium glutamate), its dose is 2%-5% of monosodium glutamate, so that it also called “super monosodium glutamate”; in addition, it also have certain supportive therapeutic efficacy for motility hepatitis, chronic hepatitis, progressive muscular dystrophy and various kinds ophthalmic diseases. 

Disodium 5'-Ribonucleotide, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). 
Disodium 5'-Ribonucleotide is a food additive with the E number E627. 

Disodium 5'-Ribonucleotide is commonly used in conjunction with glutamic acid. 
As Disodium 5'-Ribonucleotide is a fairly expensive additive, it is not used independently of glutamic acid; if Disodium 5'-Ribonucleotide is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. 

Disodium 5'-Ribonucleotide is produced from dried seaweed and is often added to: 
-instant noodles 

-potato chips

-other snacks

-savory rice

-tinned vegetables

-cured meats

-packaged soup

Disodium 5'-Ribonucleotides(I+G) is a flavor enhancer which is synergistic with glutamates in creating the taste of umami. 
Disodium 5'-Ribonucleotide is a mixture of disodium Inosinate (IMP) and Disodium 5'-Ribonucleotide (GMP) and is often used where a food already contains natural glutamates (as in meat extract) or added Monosodium Glutamate (MSG). 
Disodium 5'-Ribonucleotide is primarily used in flavored noodles, snack foods, chips, crackers, sauces and fast foods

Disodium 5'-Ribonucleotide  is a food additive that is used as a flavor enhancer, that is, to artificially increase the taste of a product.
Disodium 5'-Ribonucleotide is inserted above all in products that have monosodium glutamate inside and it is labeled in the list of food additives with the number E635.
Disodium 5'-Ribonucleotide is in the list of food additives for which levels of use and / or concentration data are required.

PHYSICAL PROPERTIES:

-Molecular Weight: 407.18

-Exact Mass: 407.02188792    

-Monoisotopic Mass: 407.02188792    

-Topological Polar Surface Area: 207 Ų        

-Compound Is Canonicalized: Yes

-Physical Description: Odourless, colourless or white crystals or white crystalline powder

-Odor: Odourless

-Color: White/Colorless

-Form: White crystals

-Solubility: Soluble in water, sparingly soluble in ethanol, practically insoluble in ether

-pH: 7,0-8,5

-Boiling Point: 890.20 °C

-Flash Point: 492.20 °C

Disodium 5'-Ribonucleotide, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). 
Disodium 5'-Ribonucleotide is a food additive with the E number E627.
Disodium 5'-Ribonucleotide is commonly used in conjunction with glutamic acid.

As Disodium 5'-Ribonucleotide is a fairly expensive additive, it is not used independently of glutamic acid; if Disodium 5'-Ribonucleotide is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides.
Disodium 5'-Ribonucleotide is produced from dried seaweed


CHEMICAL PROPERTIES:

-Heavy Atom Count: 26    

-Formal Charge: 0    

-Complexity: 586    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 4    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 3

-Hydrogen Bond Donor Count: 4    

-Hydrogen Bond Acceptor Count: 10    

-Rotatable Bond Count: 3


However, this compound also occurs naturally in foods like fish and mushrooms. 
For instance, dried shiitake mushrooms pack 150 mg in every 3.5 ounces (100 grams)
Disodium 5'-Ribonucleotide may be listed as “yeast extract” or “natural flavors” in an ingredient list.

Disodium 5'-Ribonucleotide is added to prepackaged snacks, cereals, instant noodles, canned soups, and other processed goods
Though Disodium 5'-Ribonucleotide also occurs naturally in foods like fish and mushrooms.

Disodium 5'-Ribonucleotide and MSG are both used to add a meaty or savory flavor to foods. 
Disodium 5'-Ribonucleotide is produced by fermentation, usually of tapioca starch, although it can come from other vegetable sources as well. 
Disodium 5'-Ribonucleotide can be classified under "natural flavors" on a food label, so it isn't always easy to determine if a food contains this additive.

Substituents:    

*Carboxylic acid ester
*Enediol
*Lactone
*Alcohol
*Organic oxide
*Hydrocarbon derivative
*Organic cation
*Aliphatic heteromonocyclic compound
*2-furanone
*Enoate ester
*Alpha,beta-unsaturated carboxylic ester
*Vinylogous acid

Disodium 5'-Ribonucleotide or disodium 5′-guanylate, a flavor enhancer with the European food additive number E627. 
Disodium 5'-Ribonucleotide is a kind of nucleotide and usually added with another flavor enhancer disodium inosinate (E631) in food and the combination is known as disodium 5′-ribonucleotides (E635), which is an MSG substitute. 
Disodium 5'-Ribonucleotide is the organic disodium salt of guanylic acid powder or granular, the manufacturing processes are similar with that of producing disodium inosinate. 

Disodium 5′-guanylate is a flavor enhancer that can be used in many processed foods to strengthen the umami taste or generate a savory, meaty, or broth-like taste, commonly by the combination with MSG or conjunction with disodium inosinate.
Disodium 5'-Ribonucleotide's flavor-enhancing power is around 2 times of disodium 5′-inosinate.
The common applications include instant noodles, snack food, potato chips, sauces, tinned vegetables, cured meats and so on.

Disodium 5'-Ribonucleotide, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP). Disodium 5'-Ribonucleotide is a food additive with the E number E627. 
Disodium 5'-Ribonucleotide is commonly used in conjunction with glutamic acid. 

As Disodium 5'-Ribonucleotide is a fairly expensive additive, it is not used independently of glutamic acid; if Disodium 5'-Ribonucleotide is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. 
Disodium 5'-Ribonucleotide is produced from dried seaweed and is often added to instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats, and packaged soup.

Disodium 5'-Ribonucleotide (E627), also known as sodium 5'-guanylate and disodium 5'-guanylate, is the disodium salt of the flavor enhancer guanosine monophosphate (GMP). 
Disodium 5'-Ribonucleotide is a food additive and is usually used in synergy with glutamic acid.

As Disodium 5'-Ribonucleotide is a fairly expensive additive, it is not used independently of glutamic acid; if Disodium 5'-Ribonucleotide is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex. 
Disodium 5'-Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides.
Disodium 5'-Ribonucleotide is produced from dried fish or dried seaweed and is often added to instant noodles, potato chips and snacks, savoury rice, tinned vegetables, cured meats, packet soup.

Disodium 5'-Ribonucleotide is one of the most used food improvers that can be found in a wide variety of products. 
Disodium 5'-Ribonucleotide is often combined with other flavor enhancers such as monosodium glutamate.
Disodium 5'-Ribonucleotide is a widely used food additive. 
In fact, Disodium 5'-Ribonucleotide is a type of salt derived from guanosine monophosphate (GMP).


SYNONYMS:

disodium 5'-O-phosphonatoinosine
disodium 5'-ribonucleotide
disodium inosine 5'-monophosphate
disodium inosine 5'-phosphate
disodium inosine-5'-monophosphate
sodium 5'-ribonucleotides
sodium ribonucleotides
Guanosine 5'-monophosphate disodium salt
DISODIUM 5'-GUANYLATE
Disodium 5'-Ribonucleotide
5'-Guanylic acid, disodium salt
Disodium GMP
Disodium 5'-gmp
GMP disodium salt
Disodium guanosine-5'-monophosphate
5'-Gmp disodium salt
5-Guanylic acid disodium salt
5'-Guanylic acid disodium salt
Guanosine 5'-monophosphate, disodium salt
Disodium guanosine 5'-monophosphate
Guanosine 5'-phosphate disodium salt
Sodium guanylate
Sodium ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate
Guanosine-5'-monophosphate disodium salt
GMP sodium salt
Sodium GMP
Sodium 5'-guanylate
disodium;[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Guanylic acid sodium salt
Guanosine 5'-monophosphate disodium salt hydrate
Guanosine 5'-(disodium phosphate)
Guanosine 5'MP, disodium salt
Sodium guanosine 5'-monophosphate
Disodium 5'-guanylate (VAN)
CCRIS 6561
5'-Guanylic acid, sodium salt
5'-Guanylic acid, sodium salt (1:2)
disodium 5'--guanylate
GMP sodium salt hydrate
5'-GMP 2Na hydrate
GMP disodium salt hydrate
5'-guanylic acid disodium
5'-GMP 2Na
5'-GMP-Na2
Disodium 5'-guanylate hydrate
disodium 5'-O-phosphonatoguanosine
Guanosine-5'phosphate disodium salt
5'-Guanylic acid disodium salt hydrate

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