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E 122 CARMOISINE

E 122 Carmoisine is often added to products like beverages, candies, and processed foods to provide a bright red color. 
E 122 Carmoisine, is an azo dye consisting of two naphthalene subunits.
E 122 Carmoisine, is a synthetic red azo dye commonly used in food and cosmetics. 

CAS Number: 3567-69-9
Molecular Formula: C20H15N2NaO7S2
Molecular Weight: 482.46
EINECS Number: 222-657-4

Synonyms: Carmoisine, 3567-69-9, Chromotrope FB, Acid red 14, C.I. Acid Red 14, Azo Rubine, Azorubin, C.I. 14720, Acid Rubine, Brilliant Crimson Red, Poloxal Red 2B, azorubine, C.I. Food Red 3, CI Acid Red, Carmoisin [German], Karmesin, Nacarat, Nacarat (VAN), Carmoisine ba, Carmoisine bss, Carmoisine fu, Carmoisine ws, Carmoisin, Carmoisine S, Carmoisine supra, Carmoisine W, Solar Rubine, Chromotrop FB, CI Food Red 3, HD Carmoisine, Azo rubine af, Carmoisine GRN, Carmoisine LAS, Omega Chrome Blue FB, Azo Rubin Extra, Cilefa Rubine R, Acetacid Red B, Kiton Rubine R, Crimson EMBL, Erio Rubine B, Java Rubine N, Azo rubin XX, Eurocert Azorubine, Fenazo Red C, Hexacol Carmoisine, Nacarat A Export, Nacarat Extra Pure 1A, Azo Rubine LZ, Azo Rubine XX, Neklacid rubine W, Tertracid Red CA, Acid Rubine Extra, Airedale carmoisine, Hispacid Rubine F, Pontacyl Rubine R, C.I. Acid Red 14, Disodium Salt, Carmoisine BA-CF, Crimson 2EMBL, Kiton Crimson 2R, Bucacid Azo Rubine, Hidacid Azo Rubine, Standacol carmoisine, Amacid carmoisine B, Brilliant Carmoisine, Calcocid Rubine XX, Solochrome Blue FB, Acid Fast Red FB, Azo rubine extra lc, Cerven kysela 14, Kenachrome Blue 2R, Acid Red 2C, Food Red 5, HD Carmoisine Supra, Atul Crystal Red F, Neklacid Azorubine W, Azo Rubine for Food, Brilliant Crimson 2R. FQ, CI ACID RED 14, Tertrochrome Blue FB, Certicol Carmoisine S, Food Red 3, Acid Chrome Blue BA, Cerven kysela 14 [Czech], Amacid Chrome Blue R, Diadem Chrome Blue G, Diadem Chrome Blue R, Nacarat Extra Pure A, Acid Chrome Blue 2R, Chrome Fast Blue 2R, Acid Chrome Blue FBS, Atul Acid Crystal Red, CCRIS 163, Schultz Nr. 208, Cerven potravinarska 3, Nylomine Acid Red P4B, Schultz Nr. 208 [German], Brilliant Acid Rubine M, 11959 Red, Cerven potravinarska 3 [Czech], Ext D & C Red No. 10, Acid Chrome Blue BA-CF, Brasilan Azo Rubine 2NS, Brilliant Crimson 2R.FQ, Acid Brilliant Rubine 2G, CI Acid Red 14, disodium salt, Edicol Supra Carmoisine W, HSDB 4137, Lighthouse Chrome Blue 2R, Acid Brilliant Rubine 2GT, CI 14720, Edicol Supra Carmoisine WS, C.I. Mordant Blue 79, E122, Eniacid Brilliant Rubine 3B, Azo Rubine S Specially Pure, NSC 7807, EINECS 222-657-4, Azo rubine (biological stain), C.I. Acid Red No. 14, Ext D and C Red No. 10, Carmoisine aluminum lake, L. Red Z 3040, Hexacol carmoisine conc., Carmoisine Aluminium Lake, NCI-C53849, Fruit Red A Extra Yellowish Geigy, DR4641L47F, E 122, CARMOISINE E122, CARMOISINE [IARC], CI-FOOD RED 3, AZORUBINE [USP-RS], CARMOISINE [MART.], Acid Brilliant Rubine A2G conc., CARMOISINE (E122), 1-Naphthalenesulfonic acid, 4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-, disodium salt, INS NO.122, CHEBI:82414, Disodium 2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonate, 4-Hydroxy-3,4'-azodi-1-naphthalenesulfonic acid, disodium salt, 4-Hydroxy-3,4'-azodi-1-naphthalenesulphonic acid, disodium salt, INS-122, 1-Naphthalenesulfonic acid, 4-hydroxy-3,4'-azodi-, disodium salt, 2-(4-Sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid, disodium salt, Poloxal Red 2BRED #1411959 Red, 2-(4-Sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid, disodium salt, Disodium salt of 2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid, NSC-7807, C.I. ACID RED 14 [HSDB], MFCD00003978, 4-Hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-1-naphthalenesulfonic acid, disodium salt, 4-Hydroxy-3-((4-sulpho-1-naphthalenyl)azo)-1-naphthalenesulphonic acid, disodium salt, disodium;4-hydroxy-3-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, Disodium 2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonate, CI-(1975)NO.14720, CARMOISINE (IARC), E-122, Disodium 4-hydroxy-3-((4-sulphonatonaphthyl)azo)naphthalenesulphonate, Acid Red 2S, AZORUBINE (USP-RS), CARMOISINE (MART.), 1-Naphthalenesulfonic acid, 4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-, disodium salt, 1-Naphthalenesulfonic acid, 4-hydroxy-3-(2-(4-sulfo-1-naphthalenyl)diazenyl)-, sodium salt (1:2), Azo Rubine (Technical Grade), Disodium 4-hydroxy-3-[(4-sulphonatonaphthyl)azo]naphthalenesulphonate, disodium 4-hydroxy-3-[(E)-(4-sulfonato-1-naphthyl)diazenyl]naphthalene-1-sulfonate, Sodium 4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate, Red #14, Mordant Blue 79, 1-Naphthalenesulfonic acid, 4-hydroxy-3-[2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2), Azorubin (E122), L. Red Z 304C, UNII-DR4641L47F, Carmoisine B, Carmoisine BACF, CARMOISINE A, Acid Chrome Blue BACF, AZORUBINE [MI], 4-HYDROXY-3-, Azorubin (E122) 100 microg/mL in Acetonitrile, SCHEMBL42707, SCHEMBL342870, Carmoisine, analytical standard, ACID RED 14 [INCI], BRILLIANT CRIMSON 2R-FQ, CARMOISINE WNN 19153, CHEMBL1552837, DTXSID3021225, MSK2414, OJNIRNOPCQQNRY-JZFXEGLSSA-L, AR 14, CI 14720 [INCI], Chromotrope FB (C.I. 14720), Chromotrope FB, Dye content 50 %, AKOS004901410, AKOS040759294, Azo Rubine (50per cent Dye content), Disodium 4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenesulfonate, FF40984, NCGC00164088-01, DA-62072, C.I. Acid Red 14, disodium salt (8CI), A0580, C19358, D88283, Disodium 2(4sulfo1naphthylazo)1naphthol4sulfonate, Disodium salt of 2(4sulpho1naphthylazo)1naphthol4, Q409676, Disodium 2(4sulpho1naphthylazo)1naphthol4sulphonate, 1Naphthalenesulfonic acid, 4hydroxy3,4'azodi, disodium salt, 2(4Sulfo1naphthylazo)1naphthol4sulfonic acid, disodium salt, 4Hydroxy3,4'azodi1naphthalenesulfonic acid, disodium salt, 4Hydroxy3,4'azodi1naphthalenesulphonic acid, disodium salt, 2(4Sulpho1naphthylazo)1naphthol4sulphonic acid, disodium salt, 4-HYDROXY-3,4'-AZODI-1-NAPTHALENESULFONIC ACID, DISODIUM SALT, 4Hydroxy3((4sulfo1naphthalenyl)azo)1naphthalenesulfonic acid, disodium salt, 1Naphthalenesulfonic acid, 4hydroxy3((4sulfo1naphthalenyl)azo), disodium salt, 4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-1-naphthalenesulfonic acid disodium salt, 4-HYDROXY-3-((4-SULPHO-1-NAPHTHALENYL)AZO)-1-NAPHTHALENESULFONIC ACID DISODIUM SALT, 4Hydroxy3((4sulpho1naphthalenyl)azo)1naphthalenesulphonic acid, disodium salt, DISODIUM 4-HYDROXY-3-[2-(4-SULFONATONAPHTHALEN-1-YL)DIAZEN-1-YL]NAPHTHALENE-1-SULFONATE, Azo Rubine (50% Dye content);1-Naphthalenesulfonicacid, 4-hydroxy-3-[2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodiuM salt (1:2);ChroMe becoMes priMe FB;PONTACYL RUBINE R;MORDANT BLUE 79;CI 14720 Acid red 14;Disodium 4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenesulfonate;11959red

E 122 Carmoisine is a red solid. 
E 122 Carmoisine is mainly used in foods that are heat-treated after fermentation. 
The dye is also utilized in some cosmetic and pharmaceutical products, including lipsticks and oral medications. 

Chemically, E 122 Carmoisine is a disodium salt of a naphthalenesulfonic acid derivative, and its chemical formula is C16H12N2Na2O7S2.
This dye is primarily used because of its vivid red hue, but it has been a subject of controversy in some regions due to potential links to hyperactivity in children and allergic reactions in sensitive individuals. 

As a result, some countries have restricted or mandated warnings for products containing E 122. 
E 122 Carmoisine is important for consumers to be aware of such additives, especially those with sensitivities to food colorants.
Dark red powder, soluble in water, but soluble in ethanol red solution, slightly soluble in acetone. 

In a purple color of sulfuric acid, and it will dilute to product red precipitate; Nitric acid in deep red, turn red after yellow. 
Its water solution and strong hydrochloric acid red; Add sodium hydroxide fluid shows red orange brown. 
Dyeing copper ions in slightly dark color. 

Mainly used in strong acid dye in bath dyeing wool, wool fabrics can be in silk fabric, polyamide fiber and printing. 
The Barium salt can be used as organic pigment use. Also can be used in the manufacture color amylum, ink and used for leather, paper, soap, wood, electrical-controlled silver, medicine, biology and cosmetics shading.
Azorubine is a monoazo dye that occurs as red powder or granules. 

E 122 Carmoisine is principally the disodium salt of 4-hydroxy-3-(4-sulfonato-1-naphthylazo)- 1-naphthalenesulfonate and subsidiary coloring matters together with sodium chloride and/or sodium sulfate as the principal uncolored components. 
E 122 Carmoisine may be converted to the corresponding aluminum lake.
E 122 Carmoisine is an azo dye produced as a disodium salt. 

In its dry form, the product appears red to maroon. 
E 122 Carmoisine is mainly used in foods which are heat-treated after fermentation. 
It has E number E122.

E 122 Carmoisine was delisted in 1963 because no party was interested in supporting the studies needed to establish safety.
E 122 Carmoisine was not used in food in the US.
In the EU, azorubine is known as E 122 Carmoisine, and is authorized for use in certain foods and beverages, such as cheeses, dried fruit, and some alcoholic beverages, and is permitted for use as an excipient in medications.

There are no provisions for E 122 Carmoisine in the Codex Alimentarius.
E 122 Carmoisine is an azo dye consisting of two naphthalene subunits.
E 122 Carmoisine is a red solid.

E 122 Carmoisine is mainly used in foods that are heat-treated after fermentation.
It has E number E 122.
Azorubin is coded with the code E 122 Carmoisine.

E 122 Carmoisine may come up with names such as carmoicin or CI Food Red 3.
E 122 Carmoisine is an additive that gives red color to foods.
Also, E 122 Carmoisine is in the class of articial colorants.

E 122 Carmoisine can be found in powder or granule form.
Its good solubility in water increases the usage areas.
E 122 Carmoisine is slightly soluble in ethanol.

E 122 Carmoisine can cause skin reactions and problems such as hyperactivity and distractibility in children.
Considering that the daily intake is determined as 0-4 mg/kg, it is possible for children to exceed this value.
Because they are generally used in products preferred by children.

E 122 Carmoisine is a water soluble synthetic dye. Exhibits good light fastness. 
It is available in the form of red powder. 
It is used in decorative cosmetics. 

E 122 Carmoisine meets purity criteria and characteristics set by EC Food Directive 2008/128/EC.
E 122 Carmoisine dye is used to color products in red tones.
Most often, the additive E 122 can be found in jams, syrups, marmalades, confectionery, beverages and red juices.

Additive E 122 Carmoisine is often used in mixtures with other dyes to give products complex colors (green, brown, purple, etc.).
The World Health Organization, together with the FAO,daily rateConsumption of azorubin at the level of 4 mg / kg body weight.
E 122 Carmoisine is used in the food industry, as well as in cosmetics and perfumery.

The chemical properties of the dye E 122 Azorubin are determined by the composition of the synthetically obtained food additive, which dyes the food in a red-brown color scheme.
Other names for the E 122 food additive can also be found on the food packaging, for example Carmoisine or Azorubine.
E 122 Carmoisine dye contains coal tar, which may harm the human body.

Therefore, doctors advise women not to eat foods containing E 122 Azorubin dye during pregnancy and lactation.
The World Health Organization has determined the minimum daily intake of dietary supplement E 122 Carmoisine for a healthy adult body to be 4 mg.
It is better for children and people with weakened immune systems to completely exclude the E 122 Carmoisine food supplement from their daily diet.

The use of E 122 Carmoisine dye in food production is prohibited in countries such as Austria and Sweden.
E 122 Carmoisine, is a small granules or powder of red, burgundy or dark burgundy color, well soluble in water.
E 122 Carmoisine is a derivative of coal tar, which is dangerous for human health.

The food additive E 122 Carmoisine is recognized as a carcinogenic substance, it is dangerous for the body.
By chemical composition, E 122 Carmoisine is a derivative of coal tar.
Chemical formula C20H12N2Na2O7S2.

In the European Union, E 122 Carmoisine is regulated under the E number system, where it is listed as E 122. 
It is typically safe for consumption within the allowable limits set by food safety authorities, though individuals who experience adverse reactions are advised to avoid products containing this dye. 
Additionally, Carmoisine is used in various non-food applications, such as in the textile and leather industries, where it imparts color to materials.

Despite its widespread use, there are ongoing debates regarding the safety of E 122 Carmoisine and similar synthetic dyes, with some studies suggesting a possible link to hyperactivity in children, particularly when consumed in large amounts or in combination with other artificial colors. 
Therefore, consumer awareness and regulation continue to evolve in response to these concerns.

Melting point: 254–257°C
Boiling point: 907.49℃ [at 101,325 Pa]
Flash point (Fp): >225℃
Storage temp.: Amber vial, refrigerator
Solubility: DMSO (slightly, heated), methanol (slightly), water (slightly)
Colour Index: 14720
Form: Solid
Color: Red brown
Odor: Odorless
Water solubility: Soluble in water
λmax: 383 nm; 515 nm (2nd)
ε (extinction coefficient):
≥14500 at 513–519nm in H₂O at 0.03g/L
≥33000 at 214–220nm in H₂O at 0.03g/L
≥9000 at 320–326nm in H₂O at 0.03g/L
Stability: Light sensitive
LogP: -0.001
IARC: 3 (Vol. 8, Sup 7) 1987
EPA Substance Registry System: C.I. Acid Red 14, disodium salt (3567-69-9)

E 122 Carmoisine can improve the natural color of the product or restore it if it has been lost after thermal or other processing.
E 122 Carmoisine can also color food from pink to purple, and in combination with other dyes it gives orange, brown or purple hues.
E 122 Carmoisine is a synthetic substance that belongs to the group of food additives-dyes.

As a rule, E 122 Carmoisine is used for coloring or restoring the color of foods that have undergone heat treatment.
In the international classication of food additives Azorubin, carmoisine has the index E122.
It is used in marzipan, jams, jelly rolls, yoghurts, "brown" sauces, red drinks, fruit juices.

According to some scientic data, it aects the adrenal cortex.
Consumer organizations in Australia have listed it as a food allergen for asthmatics.
Azorubin (carmoisine, food additive E 122) belongs to the group of azo dyes - synthetic dyes of red shades.

The chemical formula of the additive E 122: C20H12N2Na2O7S2.
E 122 Carmoisine belongs to coal tar derivatives.
E 122 Carmoisine dye is usually supplied in the form of a disodium salt - a red to burgundy powder.

Additive E 122 can be used to color heat-treated products after fermentation.
E 122 dye has good light fastness.
As a result of numerous studies on the food additive E 122, a number of possible negative eects on the human body have been identied.

Eating E 122 Carmoisine in food can cause allergic reactions in the form of a skin rash.
People with bronchial asthma and intolerance to anti-inammatory and antipyretic drugs (aspirin asthma) should be especially careful when using products containing E122 dye.
Recent research conducted by the University of Southampton, commissioned by the UK Food Standards Agency (FSA), has shown that eating foods containing E 122 supplements leads to increased hyperactivity and decreased alertness in children.

As a result of these studies, it was decided to ban the use of six dyes in England as of 2010.
Also, E 122 Carmoisine dye is banned in Japan, Canada, Norway, Austria, Sweden and the USA.
In some countries, supplementation with E 122 is classied as carcinogens - substances that increase the likelihood of developing cancer.

E 122 Carmoisine, is an artificial azo dye that has been widely utilized in the food and beverage industry for decades to impart a red or pink color to a variety of products. 
It is known for its deep, intense red shade and is commonly found in items such as fruit juices, jams, candies, cakes, and processed snacks. 
E 122 Carmoisine is also used in non-food products such as cosmetics, particularly in products like lipstick, blush, and eye shadows, to provide a bright and consistent color.

E 122 Carmoisines vibrant hue and low cost make it a popular choice in the manufacturing of various consumer goods.
From a chemical standpoint, E 122 Carmoisine is classified as an azo dye, a group of synthetic dyes that contain an azo group (-N=N-), which is responsible for their color. 
The dye is derived from a combination of naphthalenesulfonic acid and a diazo compound, and its structure involves a sulfonic acid group and sodium salt. 

Its chemical name is 4-hydroxy-3-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonate, and it is often referred to as a disodium salt of a naphthalenesulfonic acid derivative.
The use of Carmoisine has sparked concerns, especially in relation to potential adverse health effects. 
Studies have linked artificial food colorants, including Carmoisine, to behavioral issues such as hyperactivity, particularly in children who are sensitive to these additives. 

As a result, food products containing Carmoisine and other azo dyes are sometimes required to carry a warning label in certain countries, indicating that they may have an adverse effect on activity and attention in children. 
Additionally, research has suggested that some individuals may have allergic reactions or sensitivities to Carmoisine, manifesting as skin rashes or gastrointestinal discomfort.
In terms of safety, E 122 Carmoisine is considered safe for consumption in regulated amounts by food safety authorities like the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA). 

However, regulatory bodies have set acceptable daily intake levels to minimize any potential health risks, and these limits can vary between countries based on their own research and standards.
Although E 122 Carmoisine is approved for use in food products in many countries, its inclusion in food products is banned or restricted in some regions, where natural alternatives are preferred. 
Some manufacturers have shifted toward plant-based dyes or other natural colorants to avoid controversy and cater to the growing demand for cleaner, more natural food ingredients.

Uses:
E 122 Carmoisine is an synthetic red food dye and is used for the purposes where food is heat-treated after fermentation.
In the US, this color was listed in 1939 as Ext. D&C Red No. 10 for use in externally applied drugs and cosmetics. 
E 122 Carmoisine was delisted in 1963 because no party was interested in supporting the studies needed to establish safety. 

E 122 Carmoisine was not used in food in the US.
In the EU, azorubine is known as E 122 Carmoisine, and is authorized for use in certain foods and beverages, such as cheeses, dried fruit, and some alcoholic beverages, and is permitted for use as an excipient in medications.
There are no provisions for azorubine in the Codex Alimentarius.

E 122 Carmoisine is a synthetic red azo dye that finds widespread use in a variety of industries, particularly in the food sector, where it is used to provide a vibrant red or pink color to a range of products. 
In the food industry, Carmoisine is commonly found in processed foods such as candies, sweets, gelatin desserts, and fruit-flavored beverages. 
E 122 Carmoisine is also used in products like jams, sauces, and baked goods, where its vivid color enhances the visual appeal of the product. 

The dye is especially popular in confectionery items like gummy bears, lollipops, and jelly beans, where its ability to deliver a bright, eye-catching red makes it an attractive choice for manufacturers aiming to attract consumers, especially children.
Beyond food, E 122 Carmoisine has applications in non-food products as well. 
It is used in the cosmetics industry, where its colorant properties make it suitable for products such as lipsticks, blushes, and eye shadows, providing a consistent and long-lasting red or pink hue. 

E 122 Carmoisine is also used in toiletries, including shampoos and shower gels, to enhance their appearance with a pleasing color. 
In addition, the dye is utilized in some pharmaceutical formulations, where it may be added to tablets and capsules to aid in their identification or to make them more visually appealing.
Moreover, E 122 Carmoisine is sometimes included in the manufacturing of textiles and in the production of certain inks, particularly in printing and coloring processes. 

Although its use in textiles and ink is less common compared to food and cosmetics, it still plays a role in providing color in specialized applications. 
However, due to potential health concerns related to artificial dyes, the use of E 122 Carmoisine is subject to regulation, and manufacturers must comply with guidelines that limit its concentration in products to ensure consumer safety.
Despite its widespread use, Carmoisine is not without its controversies. 

Concerns over its potential to cause allergic reactions or behavioral effects, particularly in children, have led to increased scrutiny and regulation in many countries. 
As a result, in some regions, E 122 Carmoisine is required to be labeled on food products, and there are warnings indicating that the dye may have an adverse effect on activity and attention in susceptible individuals. 
As such, while E 122 Carmoisine remains a popular colorant in many products, its inclusion in food and cosmetics has become increasingly subject to consumer demand for natural and safer alternatives.

E 122 Carmoisine, a synthetic red azo dye, also finds its way into a variety of medicinal and health-related products, where it functions as both a colorant and a means of distinguishing between different medicines. 
It can be found in some over-the-counter medications and prescription drugs, particularly those in tablet, capsule, and liquid forms. 
The dye helps to make the medication visually distinct, which can be particularly important in pharmaceutical applications where easy identification of products is essential. 

In these cases, Carmoisine aids in ensuring that patients can quickly recognize the correct dosage and medication, which helps to prevent errors in administration.
The use of E 122 Carmoisine in pharmaceuticals is strictly regulated, with specific limitations on the concentration and usage in different product categories. 
While the dye can be found in some medicines, its inclusion is closely monitored due to concerns over its potential impact on health, especially among sensitive individuals. 

Certain groups, such as those with allergies or sensitivities to artificial food colorants, may experience adverse reactions, which can range from skin rashes to more severe allergic responses. 
Therefore, E 122 Carmoisine’s presence in pharmaceutical products is carefully controlled to minimize the risk of side effects and to ensure that the benefits of its inclusion outweigh any potential risks.

In the broader consumer goods market, E 122 Carmoisine has seen some use in the production of novelty items and craft products, including items like play dough, art supplies, and certain types of fabric dye. 
While these applications may not be as widespread as those in food and cosmetics, they still contribute to the overall demand for the dye. 
In craft products, Carmoisine may be used to create vibrant colors in play materials or as a temporary pigment in crafting activities.

Despite its versatility in various industries, E 122 Carmoisine has faced increasing scrutiny in recent years, especially with growing consumer interest in natural or organic alternatives. 
As more consumers become aware of potential health risks associated with synthetic dyes, including Carmoisine, the demand for natural food colorants like beet juice powder or spirulina extract has risen. 
Many manufacturers are responding to this shift in consumer preferences by exploring alternatives to Carmoisine, as well as other synthetic dyes, in order to meet the demand for products that are perceived as safer and healthier.

Furthermore, research on E 122 Carmoisine’s potential effects on human health continues to shape public perception and regulation. 
In addition to its potential to cause allergic reactions, studies have raised concerns about the link between artificial food colorants like Carmoisine and hyperactivity or behavioral issues in children. 

In response, some countries have implemented policies that restrict or prohibit the use of certain synthetic dyes, including Carmoisine, in products marketed to children or in foods with a high consumption rate among young audiences. 
As a result, manufacturers have been exploring more sustainable, natural alternatives to replace Carmoisine in their products, particularly in the food and beverage sectors, where clean labeling and transparency have become increasingly important to consumers.

Safety Profile:
E 122 Carmoisine has shown no evidence of mutagenic or carcinogenic properties and an acceptable daily intake (ADI) of 0–4 mg/kg was established in 1983 by the WHO.
In rare instances, it may cause skin and respiratory allergic reactions even to FDA approved dosages.
No evidence supports broad claims that food coloring causes food intolerance and ADHD-like behavior in children.

E 122 Carmoisine is possible that certain food coloring may act as a trigger in those who are genetically predisposed, but the evidence is weak.
E 122 Carmoisine has been associated with several health concerns, particularly related to its use in food and other consumer products. 
The primary hazards linked to Carmoisine stem from potential allergic reactions, sensitivities, and other adverse effects on health, particularly in certain vulnerable populations

Some individuals may experience skin reactions such as rashes, itching, or hives after exposure to Carmoisine. 
These reactions are more likely in people with known sensitivities to azo dyes or food colorants.
There are documented cases where Carmoisine has triggered asthma symptoms, especially in individuals who are prone to respiratory issues. 

This can include shortness of breath, wheezing, and difficulty breathing after exposure to the dye.
E 122 Carmoisine is known to cause allergic reactions in sensitive individuals, leading to symptoms such as swelling, difficulty swallowing, or even anaphylaxis in severe cases. 
People who are allergic to other azo dyes may be at an increased risk of reacting to Carmoisine.

Some studies have suggested a potential link between artificial food colorants, including E 122 Carmoisine, and hyperactivity or behavioral issues in children, particularly in those with attention deficit hyperactivity disorder (ADHD). 
While the evidence is not definitive, some studies have indicated that reducing synthetic dyes from children’s diets may help alleviate these behavioral issues.


 

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