E 300 Ascorbic Acid is used to enhance the nutritional content and maintain the clarity and colour of beverages.
E 300 Ascorbic Acid acts as a dough conditioner and improves the quality and shelf life of baked goods.
E 300 Ascorbic Acid helps to retain colour and prevent oxidation in processed meats.
CAS Number: 50-81-7
EC Number: 200-066-2
E Number: E300
Molecular Formula: C₆H₈O₆
Molecular Weight: 176.12 g/mol
SYNONYMS:
l-ascorbic acid, ascorbic acid, ascorbate, IUPAC, l-threo-Hex-2-enono-1,4-lactone ((R)-3,4-Dihydroxy -5-((S)- 1,2-dihydroxyethyl)furan-2(5H)-one), Ascorbic Acid, L-Ascorbic Acid, Antiscorbutic Factor, Vitamin C, Antiscorbic Vitamin, L- Ascorbic Acid (Vitamin C), L-threi-hex-enoic acid, gamma lactone, 3-keto-L-gulofuranolactone, L-3-ketotreohexuronic acid lactone, 3-oxo-L-gulofuranolactone, Vitamin C, L-Xyloasuribic acid, Ascorbic Acid, L-Ascorbic Acid, Vitamin C, E300, L-(+)-Ascorbic Acid, Antiscorbutic Vitamin, L-threo-Hex-2-enonic Acid γ-Lactone, 2,3-Didehydro-L-threo-Hexono-1,4-Lactone, 3-Keto-L-gulofuranolactone, Cebion, Cantan, Redoxon
E 300 Ascorbic Acid is a water-soluble vitamin found in citrus and other fruits, berries and vegetables.
E 300 Ascorbic Acid is also a generic prescription medication and in some countries is sold as a non-prescription dietary supplement.
As a therapy, E 300 Ascorbic Acid is used to prevent and treat scurvy, a disease caused by vitamin C deficiency.
E 300 Ascorbic Acid is an essential nutrient involved in the repair of tissue, the formation of collagen, and the enzymatic production of certain neurotransmitters.
E 300 Ascorbic Acid is required for the functioning of several enzymes and is important for immune system function.
E 300 Ascorbic Acid also functions as an antioxidant.
E 300 Ascorbic Acid may be taken by mouth or by intramuscular, subcutaneous or intravenous injection.
Various health claims exist on the basis that moderate E 300 Ascorbic Acid deficiency increases disease risk, such as for the common cold, cancer or COVID-19.
There are also claims of benefits from E 300 Ascorbic Acid supplementation in excess of the recommended dietary intake for people who are not considered vitamin C deficient.
E 300 Ascorbic Acid is generally well tolerated.
Large doses of E 300 Ascorbic Acid may cause gastrointestinal discomfort, headache, trouble sleeping, and flushing of the skin.
The United States Institute of Medicine recommends against consuming large amounts of E 300 Ascorbic Acid.
Most animals are able to synthesize their own E 300 Ascorbic Acid.
However, apes (including humans) and monkeys (but not all primates), most bats, most fish, some rodents, and certain other animals must acquire it from dietary sources because a gene for a synthesis enzyme has mutations that render E 300 Ascorbic Acid dysfunctional.
E 300 Ascorbic Acid (Vitamin C) was discovered in 1912, isolated in 1928, and in 1933, was the first vitamin to be chemically produced.
Partly for E 300 Ascorbic Acid's discovery, Albert Szent-Györgyi was awarded the 1937 Nobel Prize in Physiology or Medicine.
E 300 Ascorbic Acid is a very pure vitamin C product specially selected for application in wine, champagne, and fruit juice that protects bottled beverages from oxidation.
By using stabilization products, the beverages are microbiologically and chemically/physically stabilized and their shelf life is increased.
E 300 Ascorbic Acid is a compound with the formula C6H8O6.
E 300 Ascorbic Acid is vitamin C, or ascorbic acid or ascorbate.
E 300 Ascorbic Acid is present in most plant products and is required for the synthesis of enzymes, neurotransmitters and for the proper functioning of the immune system.
E 300 Ascorbic Acid also has antioxidant properties.
E 300 Ascorbic Acid is the chemical name for vitamin C.
E 300 Ascorbic Acid is a water-soluble variant of vitamin C.
The addition of the E number ensures that E 300 Ascorbic Acid itself has a longer shelf life.
E 300 Ascorbic Acid, more commonly known as vitamin C, is a water-soluble vitamin.
Since E 300 Ascorbic Acid cannot be produced by the human body, it must be supplied externally.
The basic structure of E 300 Ascorbic Acid is shaped on a carbohydrate structure with a hexagonal ring.
Being a particularly powerful antioxidant, E 300 Ascorbic Acid protects cells from the harmful effects of free radicals.
To understand ascorbic acid, E 300 Ascorbic Acid is useful to know some of its basic properties.
E 300 Ascorbic Acid - Vitamin C, one of the most valuable nutrients offered by nature, has many important health benefits.
E 300 Ascorbic Acid, which is vital for the human body, is known for strengthening the immune system, accelerating the healing process of wounds and protecting skin health.
E 300 Ascorbic Acid is found in many fruits and vegetables that we frequently encounter in our daily lives.
However, E 300 Ascorbic Acid - Vitamin C deficiency can cause various health problems.
E 300 Ascorbic Acid is a premium quality product.
Also known as Vitamin C powder E 300 Ascorbic Acid can be used to prevent browning.
When used to strengthen dough whilst making bread E 300 Ascorbic Acid has a beneficial effect on the volume, crumb structure and softness.
E 300 Ascorbic Acid is a natural ingredient that is suitable for Vegans & Vegetarians, Non-GMO, Gluten Free, Non-Irradiated.
E 300 Ascorbic Acid is also known as Vitamin C powder.
E 300 Ascorbic Acid is geat for preventing oxidation (browning).
Suitable for Vegans, Non-GMO, Gluten Free, Non-Irradiated.
E 300 Ascorbic Acid is an additive approved by the EU (European Union) and used as a natural antioxidant in food and drink products.
The common name for E300 is E 300 Ascorbic Acid, which is also known as Vitamin C.
Although a natural antioxidant occurring in most fruits and vegetables, E 300 Ascorbic Acid can also be produced synthetically from the fermentation and oxidation of glucose.
USES and APPLICATIONS of E 300 ASCORBIC ACID:
Agricultural Industry: Leaf Spray: E 300 Ascorbic Acid helps protect crops from stress factors and increase yield.
Water Treatment: Reducing Agent: E 300 Ascorbic Acid is effective in removing chlorine and harmful substances from water.
Applications Food Preservation: E 300 Ascorbic Acid prevents oxidation and spoilage in a wide variety of food products, such as fruits and vegetables, juices, and processed foods.
Beverages: E 300 Ascorbic Acid is used to enhance the nutritional content and maintain the clarity and colour of beverages.
Bakery: E 300 Ascorbic Acid acts as a dough conditioner and improves the quality and shelf life of baked goods.
Meat Processing: E 300 Ascorbic Acid helps to retain colour and prevent oxidation in processed meats.
Nutritional Supplements: E 300 Ascorbic Acid is incorporated into dietary supplements for its health benefits and to support the immune system.
Confectionery: E 300 Ascorbic Acid is used to maintain the freshness and appearance of candies and other sweet products.
In the food industry, E 300 Ascorbic Acid is used as a means of stabilizing the color of a product, giving it a savory, acidic flavor that is not very strong but reminiscent of a slightly sour, tasty fruit.
E 300 Ascorbic Acid is very often found in sauces, condiments, gummies and fruit waters.
E 300 Ascorbic Acid-treated food should not be cooked, as it is lost in two ways: one when it leaves the product, the other when it becomes inactive, where it is not absorbed by the body.
In sports nutrition, E 300 Ascorbic Acid is used in a variety of forms, in tablets, capsules, powders and vitamin drinks.
The most common intakes range from 25 mg to 1500 mg per serving.
Amounts may vary if there is a high level of physical activity and frequent temperature changes (autumn, winter, early spring), as E 300
Ascorbic Acid is involved in respiration and energy release, and its consumption is higher in these conditions.
As E 300 Ascorbic Acid is a water-soluble vitamin, an overdose is virtually impossible.
E 300 Ascorbic Acid is considered to be one of the safest and most effective nutritional additives needed for human health.
In animal husbandry, the vitamin helps to protect against and treat diseases associated with ageing, cellular stress caused by physical activity or joint degeneration (arthritis).
E 300 Ascorbic Acid neutralizes free radicals in the body (antioxidant), and also helps the recovery of vitamin E, which is a powerful natural antioxidant, involved in iron metabolism and in some anti-infective immune reactions.
E 300 Ascorbic Acid improves the balance of alkalis and acids in the body and protects against and dissolves struvite bladder stones.
However, it is not recommended if the cat has been diagnosed with oxalate stones.
High concentrations of E 300 Ascorbic Acid in the body are found in areas of intense fibroplasia.
This demonstrates the involvement of vitamin C in tissue regeneration.
Vitamin C is involved in fat metabolism (inhibiting the action of the enzyme lipase) and in cholesterol metabolism - a deficiency of vitamin C leads to an increase in cholesterol levels in the liver and in the blood serum.
Sulphated metabolites of E 300 Ascorbic Acid cause the formation of cholesterol sulphate from cholesterol and excretion in the urine.
E 300 Ascorbic Acid also promotes the resorption of iron ions in the intestine.
These ions are further utilised by bone marrow cells, so that E 300 Ascorbic Acid is involved in erythrocyte production and hemoglobin synthesis.
E 300 Ascorbic Acid reduces the permeability of blood capillaries in atopic conditions and inflammation, and also protects the arteries against sclerosis by preventing the accumulation of cholesterol in the blood vessel walls.
Iron, copper, zinc, calcium ions and flavonoids enhance the biological effects of vitamin C.
E 300 Ascorbic Acid prevents the concentration of uric acid in heart muscle cells from rising and inhibits the formation of free radicals that damage heart muscle cells in the event of endotoxemia.
E 300 Ascorbic Acid is involved in the suppression of inflammatory processes due to its antioxidant and adrenal stimulating action.
E 300 Ascorbic Acid also helps birds and livestock to tolerate heat more easily, to maintain electrolyte balance and not to stunt their growth.
In medicine, E 300 Ascorbic Acid can maintain the acid-base balance in the human body and restore normal nerve function.
E 300 Ascorbic Acid can be used in the treatment of cancer to enhance the effects of chemotherapy.
People who get enough E 300 Ascorbic Acid from fruit and vegetables have a lower risk of developing lung, breast, and colon cancer.
Very high concentrations of E 300 Ascorbic Acid in the blood help tumors to shrink.
AMD (age-related macular degeneration) and cataracts.
These are the two main causes of sight loss in older age.
Studies show that E 300 Ascorbic Acid combined with other nutrients in the early stages of AMD can slow the progression of the disease.
People who take E 300 Ascorbic Acid regularly can alleviate their cold symptoms and recover faster.
In cosmetics E 300 Ascorbic Acid is used for its antioxidant and skin brightening properties.
E 300 Ascorbic Acid is most commonly found in products for mature skin, as well as in serums designed to brighten the skin and lighten pigmented spots, and can also be found in exfoliants.
E 300 Ascorbic Acid can be used as a preservative or as part of a preservative system.
E 300 Ascorbic Acid acts as a keratolytic, brightening the skin and lightening pigmented spots; stimulates collagen production, thereby reducing the wrinkle network; has anti-inflammatory properties.
E 300 Ascorbic Acid may cause skin irritation and should therefore be used in combination with soothing ingredients.
E 300 Ascorbic Acid is most effective on the skin when properly incorporated into the formula: in combination with other antioxidants, in a sufficiently high concentration (15-20%), with the right pH, and in appropriate packaging protected from oxygen and light.
E 300 Ascorbic Acid is a food acid used to extend the shelf life of a product.
E 300 Ascorbic Acid has multiple uses, but is most often used to ensure the quality of bread.
In the food industry, E 300 Ascorbic Acid is widely used in various products, such as fruit juices and confectionery.
In this way, the shelf life of E 300 Ascorbic Acid is extended and their fresh appearance is preserved.
E 300 Ascorbic Acid also has the potential to reduce the risk of anemia by increasing the body's absorption of iron.
E 300 Ascorbic Acid's usage areas are generally medical.
The purposes of use here are to use as a source of E 300 Ascorbic Acid.
E 300 Ascorbic Acid has antioxidant effects as a preservative in foods.
E 300 Ascorbic Acid helps prevent the color, texture and flavor of foods from changing.
If we add Vitamin C to dried meats, E 300 Ascorbic Acid keeps their red color.
E 300 Ascorbic Acid prevents the formation of reactions that cause the formation of nitrosamines, which are found in cured meats and can increase the risk of cancer.
E 300 Ascorbic Acid prevents the growth of bacteria as it will reduce food-borne diseases and food spoilage.
E 300 Ascorbic Acid is a natural food preservative.
In medicines produced for the common cold, 300 mg E 300 Ascorbic Acid is used together with pseudoepherine hydrochloride raw material.
At the same time, a thickening agent and filler are used in this application.
The binding agent, E 300 Ascorbic Acid, of this formula is polyvinyl alcohol.
E 300 Ascorbic Acid is used to delay the oxidative odor found in oils or that may occur.
As a curing agent to inhibit the formation of nitrosamines in meat processing systems.
E 300 Ascorbic Acid has been determined that it keeps the color quality at a stable level in meats cured with Sodium Nitrate and Sodium Nitrite.
E 300 Ascorbic Acid is used in bread baking processes, to improve the quality of wheat flour and dough.
E 300 Ascorbic Acid is used to protect against browning in processed fruits and vegetables due to enzyme reactions.
E 300 Ascorbic Acid is used in the alcohol sector to maintain the clarity of wine and beer.
E 300 Ascorbic Acid is used in the pharmaceutical sector in the manufacture of drugs used to treat patients with colds.
These drugs are applied in powder form and added to water.
Dietary Supplements: E 300 Ascorbic Acid is used to support the immune system and acts as an antioxidant.
Pharmaceuticals: E 300 Ascorbic Acid is used to treat vitamin C deficiency and included in various drug formulations.
Cosmetics: E 300 Ascorbic Acid is incorporated in skincare products for its antioxidant properties and skin-brightening effects.
Food Preservative: E 300 Ascorbic Acid prevents oxidation in food products.
E 300 Ascorbic Acid is a sugar acid that is most commonly used as a bread enhancer by acting as a flour-treating agent. E 300 Ascorbic Acid should be included in the diet every day because only a little is stored in the body.
Lack of E 300 Ascorbic Acid may lead to scurvy because vitamin C is important for the healthy development of bones, teeth and blood vessels.
E 300 Ascorbic Acid may also act to reduce wrinkles by aiding to production of collagen in the skin.
E 300 Ascorbic Acid is used to strengthen dough when making bread for a beneficial effect on the volume, crumb structure and softness.
-Bakery Products and E 300 Ascorbic Acid
Ascorbic acid is widely used in bakery products to improve dough quality, enhance the fermentation process, and improve product texture.
-Food Industry uses of E 300 Ascorbic Acid:
*Antioxidant:
E 300 Ascorbic Acid extends the freshness and shelf life of foods by preventing oxidation of fats.
*Preservative:
E 300 Ascorbic Acid prevents spoilage in fruit juices, canned fruits, and vegetables.
-Bakery Products uses of E 300 Ascorbic Acid:
*Dough Strengthening:
E 300 Ascorbic Acid strengthens the gluten network, improving dough workability.
*Volume Increase:
E 300 Ascorbic Acid enhances rising capacity during fermentation, resulting in fluffier and lighter products.
*Shelf Life Extension:
E 300 Ascorbic Acid delays staling by slowing down starch crystallization.
*Texture Improvement:
E 300 Ascorbic Acid helps achieve softer and more homogeneous products.
-Pharmaceutical Industry uses of E 300 Ascorbic Acid:
*Vitamin C Supplement:
E 300 Ascorbic Acid is used to prevent and treat scurvy.
*Immune System:
E 300 Ascorbic Acid helps prevent or alleviate colds and flu.
-Cosmetic Industry uses of E 300 Ascorbic Acid
*Skin Care:
E 300 Ascorbic Acid promotes collagen production, tightening the skin and providing protection against free radicals.
*Anti-Aging:
E 300 Ascorbic Acid offers skin brightening and spot-reducing properties.
IN WHICH FOODS AND DRINKS IS E 300 ASCORBIC ACID USED AS AN ADDITIVE?
E 300 Ascorbic Acid is found naturally in citrus fruits, mostly lemons, oranges and grapefruits.
However, E 300 Ascorbic Acid is also used as an additive in many processed foods and beverages.
For example, E 300 Ascorbic Acid is preferred in ready-made fruit juices and carbonated drinks to prevent oxidation of products and extend their shelf life.
In addition, E 300 Ascorbic Acid is frequently used in canned vegetables and fruits.
E 300 Ascorbic Acid is effective in preserving the color of foods.
E 300 Ascorbic Acid prevents flavor loss in advance, especially in frozen products.
FOOD PRESERVATION ADDITIVE, E 300 ASCORBIC ACID:
E 300 Ascorbic Acid and some of its salts and esters are common additives added to foods such as canned fruits, mostly to slow oxidation and enzymatic browning.
E 300 Ascorbic Acid may be used as a flour treatment agent used in breadmaking.
As food additives, they are assigned E numbers, with safety assessment and approval the responsibility of the European Food Safety Authority.
CHEMISTRY OF E 300 ASCORBIC ACID:
*Pharmacology
Pharmacodynamics is the study of how the drug – in this instance vitamin C – affects the organism, whereas pharmacokinetics is the study of how an organism affects the drug.
*Pharmacodynamics
Pharmacodynamics includes enzymes for which E 300 Ascorbic Acid is a cofactor, with function potentially compromised in a deficiency state, and any enzyme cofactor or other physiological function affected by administration of vitamin C, orally or injected, in excess of normal requirements.
At normal physiological concentrations, E 300 Ascorbic Acid serves as an enzyme substrate or cofactor and an electron donor antioxidant.
The enzymatic functions include the synthesis of collagen, carnitine, and neurotransmitters; the synthesis and catabolism of tyrosine; and the metabolism of microsomes.
In nonenzymatic functions E 300 Ascorbic Acid acts as a reducing agent, donating electrons to oxidized molecules and preventing oxidation in order to keep iron and copper atoms in their reduced states.
At non-physiological concentrations achieved by intravenous dosing, E 300 Ascorbic Acid may function as a pro-oxidant, with therapeutic toxicity against cancer cells.
WHAT IS THE ROLE OF E 300 ASCORBIC ACID IN THE FOOD INDUSTRY?
E 300 Ascorbic Acid is an important additive known in the food industry with the code E300.
E 300 Ascorbic Acid, often called vitamin C , functions to extend the shelf life of foods and preserve color.
However, E 300 Ascorbic Acid is also frequently used in the health field due to its positive effects on the immune system.
Food manufacturers often prefer E 300 Ascorbic Acid, especially in fruit juice and vegetable products.
In addition, E 300 Ascorbic Acid prevents spoilage by preventing the development of microorganisms because it creates an acidic environment.
Think of E 300 Ascorbic Acid like a star player; he takes the stage alone but is actually in perfect harmony with his teammates.
However, there may be confusion here; some may think that E 300 Ascorbic Acid only provides vitamin support, but the truth is much more complex.
In addition, E 300 Ascorbic Acid is available in natural and synthetic forms.
Which form is used stands out as a factor that determines the quality of E 300 Ascorbic Acid.
WHAT ARE THE ANTIOXIDANT PROPERTIES OF E 300 ASCORBIC ACID AND HOW DO THEY AFFECT THESE FOOD?
E 300 Ascorbic Acid, or vitamin C as we know it, plays an important role in our body as a powerful antioxidant.
E 300 Ascorbic Acid protects our cells by fighting free radicals and supports our immune system.
E 300 Ascorbic Acid, which is found abundantly in fruits and vegetables, plays an active role in many biological processes in our body.
For example, E 300 Ascorbic Acid reduces the risk of anemia by increasing the absorption of iron.
The potential of E 300 Ascorbic Acid makes it indispensable for skin health.
While repairing skin damage, E 300 Ascorbic Acid also delays the signs of aging by promoting collagen synthesis.
WHAT ARE THE HEALTH BENEFITS OF E 300 ASCORBIC ACID?
E 300 Ascorbic Acid, known as vitamin C , is a vital compound for human health.
E 300 Ascorbic Acid, which has many functions in the body, stands out for strengthening the immune system.
E 300 Ascorbic Acid is recommended to consume more, especially during cold and flu season.
However, E 300 Ascorbic Acid also helps protect cells from oxidative stress thanks to its antioxidant properties.
BENEFITS OF E 300 ASCORBIC ACID:
Some of the most important health benefits of E 300 Ascorbic Acid include:
*Immune support:
E 300 Ascorbic Acid protects the body against infections.
*Collagen production:
E 300 Ascorbic Acid improves skin health and contributes to rapid healing of wounds.
*Iron absorption:
E 300 Ascorbic Acid increases the absorption of iron from plant sources.
However, E 300 Ascorbic Acid should be noted that excessive vitamin C intake can lead to some side effects.
Therefore, taking E 300 Ascorbic Acid in a balanced way provides the most health efficiency.
E 300 Ascorbic Acid can be obtained from both sources and supplements.
E 300 Ascorbic Acid is possible to fully benefit from the potential benefits of Ascorbic Acid by making careful choices.
CHEMICAL PROPERTIES OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid is soluble in water as 400 g/L.
E 300 Ascorbic Acid's melting point is 374 °F- 378 °F.
In terms of solubility, E 300 Ascorbic Acid is insoluble in ether, chloroform, benzene ether, oils and some solvents.
E 300 Ascorbic Acid's density is 1.65 g/cm3.
E 300 Ascorbic Acid is a flammable chemical.
KEY INCI FUNCTIONS OF E 300 ASCORBIC ACID:
*Antioxidant:
E 300 Ascorbic Acid inhibits reactions stimulated by oxygen, preventing oxidation and rancidity
*pH regulator:
E 300 Ascorbic Acid stabilizes the pH of cosmetics
*Masking:
E 300 Ascorbic Acid reduces or suppresses the odor or main flavor of the product
*Skin conditioning:
E 300 Ascorbic Acid maintains good skin condition
FUNCTION & CHARACTERISTICS OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid is vitamin C; however, it cannot be added as a vitamin supplement when labelled E300.
When added to foods E 300 Ascorbic Acid functions as an anti-oxidant and bread enhancer.
E 300 Ascorbic Acid, commonly known as vitamin C, is a powerful antioxidant famous for its benefits on health and immune system.
In cooking, E 300 Ascorbic Acid is used to keep the green vivid colours of vegetables and stops the oxidation of peeled aliments (apple, pear, banana, artichoke,...).
In butchery and cooked meats, E 300 Ascorbic Acid maintains the meat colour.
In bakery, E 300 Ascorbic Acid is used as a flour ‘improver’ or dough conditioner.
In the presence of oxygen, E 300 Ascorbic Acid becomes an oxidising agent and the improvements to which it contributes include strengthened gluten, greater loaf volume, finer and increased tenderness of the crumb, faster rising.
E 300 Ascorbic Acid with a concentration range of 40-80 M, is a six-carbon compound related to glucose.
E 300 Ascorbic Acid is a high-purity, crystalline powder renowned for its potent antioxidant properties.
Commonly known as Vitamin C, E 300 Ascorbic Acid is widely used in the food and beverage industry for its health benefits and ability to preserve freshness and colour.
E 300 Ascorbic Acid is found naturally in citrus fruits and many vegetables.
E 300 Ascorbic Acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone.
With the E number 300, E 300 Ascorbic Acid cannot be produced or stored by humans and must be obtained in the diet.
CHEMISTRY OF E 300 ASCORBIC ACID:
The name "vitamin C" always refers to the l-enantiomer of E 300 Ascorbic Acid and its oxidized form, dehydroascorbate (DHA).
Therefore, unless written otherwise, "ascorbate" and "E 300 Ascorbic Acid" refer in the nutritional literature to l-ascorbate and l-ascorbic acid respectively.
E 300 Ascorbic Acid is a weak sugar acid structurally related to glucose.
In biological systems, E 300 Ascorbic Acid can be found only at low pH, but in solutions above pH 5 it is predominantly found in the ionized form, ascorbate.
Many analytical methods have been developed for E 300 Ascorbic Acid detection.
For example, E 300 Ascorbic Acid content of a food sample such as fruit juice can be calculated by measuring the volume of the sample required to decolorize a solution of dichlorophenolindophenol (DCPIP) and then calibrating the results by comparison with a known concentration of vitamin C.
BENEFITS OF E 300 ASCORBIC ACID:
*High-purity formulation for food and beverage use
*Meets European standard E 300 Ascorbic Acid ensuring quality and safety
*Potent antioxidant properties to prevent oxidation and preserve freshness
*E 300 Ascorbic Acid enhances nutritional value as a Vitamin C supplement
*E 300 Ascorbic Acid improves colour retention and stability in food products.
FUNCTIONS AS A COFACTOR, E 300 ASCORBIC ACID:
E 300 Ascorbic Acid functions as a cofactor for the following enzymes:
Three groups of enzymes (prolyl-3-hydroxylases, prolyl-4-hydroxylases, and lysyl hydroxylases) that are required for the hydroxylation of proline and lysine in the synthesis of collagen.
These reactions add hydroxyl groups to the amino acids proline or lysine in the collagen molecule via prolyl hydroxylase and lysyl hydroxylase, both requiring E 300 Ascorbic Acid as a cofactor.
The role of E 300 Ascorbic Acid as a cofactor is to oxidize prolyl hydroxylase and lysyl hydroxylase from Fe2+ to Fe3+ and to reduce it from Fe3+ to Fe2+.
Hydroxylation allows the collagen molecule to assume its triple helix structure, and thus E 300 Ascorbic Acid is essential to the development and maintenance of scar tissue, blood vessels, and cartilage.
Two enzymes (ε-N-trimethyl-L-lysine hydroxylase and γ-butyrobetaine hydroxylase) are necessary for synthesis of carnitine.
Carnitine is essential for the transport of fatty acids into mitochondria for ATP generation.
Hypoxia-inducible factor-proline dioxygenase enzymes (isoforms: EGLN1, EGLN2, and EGLN3) allows cells to respond physiologically to low concentrations of oxygen.
Dopamine beta-hydroxylase participates in the biosynthesis of norepinephrine from dopamine.
Peptidylglycine alpha-amidating monooxygenase amidates peptide hormones by removing the glyoxylate residue from their c-terminal glycine residues.
This increases peptide hormone stability and activity.
As an antioxidant, E 300 Ascorbic Acid scavenges reactive oxygen and nitrogen compounds, thus neutralizing the potential tissue damage of these free radical compounds.
Dehydroascorbate, the oxidized form, is then recycled back to E 300 Ascorbic Acid by endogenous antioxidants such as glutathione.
In the eye, E 300 Ascorbic Acid is thought to protect against photolytically generated free-radical damage; higher plasma E 300 Ascorbic Acid is associated with lower risk of cataracts.
E 300 Ascorbic Acid may also provide antioxidant protection indirectly by regenerating other biological antioxidants such as α-tocopherol back to an active state.
In addition, E 300 Ascorbic Acid also functions as a non-enzymatic reducing agent for mixed-function oxidases in the microsomal drug-metabolizing system that inactivates a wide variety of substrates such as drugs and environmental carcinogens.
*Pharmacokinetics
E 300 Ascorbic Acid is absorbed in the body by both active transport and passive diffusion.
Approximately 70%–90% of vitamin C is active-transport absorbed when intakes of 30–180 mg/day from a combination of food sources and moderate-dose dietary supplements such as a multi-vitamin/mineral product are consumed.
However, when large amounts are consumed, such as a vitamin C dietary supplement, the active transport system becomes saturated, and while the total amount being absorbed continues to increase with dose, absorption efficiency falls to less than 50%.
Active transport is managed by Sodium-E 300 Ascorbic Acid Co-Transporter proteins (SVCTs) and Hexose Transporter proteins (GLUTs).
SVCT1 and SVCT2 import E 300 Ascorbic Acid across plasma membranes.
The Hexose Transporter proteins GLUT1, GLUT3 and GLUT4 transfer only the oxydized dehydroascorbic acid (DHA) form of vitamin C.
The amount of DHA found in plasma and tissues under normal conditions is low, as cells rapidly reduce DHA to E 300 Ascorbic Acid.
SVCTs are the predominant system for vitamin C transport within the body.
In both vitamin C synthesizers (example: rat) and non-synthesizers (example: human) cells maintain ascorbic acid concentrations much higher than the approximately 50 micromoles/liter (μmol/L) found in plasma.
For example, the ascorbic acid content of pituitary and adrenal glands can exceed 2,000 μmol/L, and muscle is at 200–300 μmol/L.
The known coenzymatic functions of ascorbic acid do not require such high concentrations, so there may be other, as yet unknown functions.
A consequence of all this high concentration organ content is that plasma vitamin C is not a good indicator of whole-body status, and people may vary in the amount of time needed to show symptoms of deficiency when consuming a diet very low in vitamin C.
Excretion (via urine) is as ascorbic acid and metabolites.
The fraction that is excreted as unmetabolized ascorbic acid increases as intake increases.
In addition, ascorbic acid converts (reversibly) to DHA and from that compound non-reversibly to 2,3-diketogulonate and then oxalate.
These three metabolites are also excreted via urine.
During times of low dietary intake, vitamin C is reabsorbed by the kidneys rather than excreted.
This salvage process delays onset of deficiency.
Humans are better than guinea pigs at converting DHA back to E 300 Ascorbic Acid, and thus take much longer to become vitamin C deficient.
SYNTHESIS OF E 300 ASCORBIC ACID:
Most animals and plants are able to synthesize vitamin C through a sequence of enzyme-driven steps, which convert monosaccharides to vitamin C.
Yeasts do not make l-ascorbic acid but rather its stereoisomer, erythorbic acid.
In plants, synthesis is accomplished through the conversion of mannose or galactose to ascorbic acid.
In animals, the starting material is glucose.
In some species that synthesize E 300 Ascorbic Acid in the liver (including mammals and perching birds), the glucose is extracted from glycogen;
E 300 Ascorbic Acid synthesis is a glycogenolysis-dependent process.
In humans and in animals that cannot synthesize vitamin C, the enzyme l-gulonolactone oxidase (GULO), which catalyzes the last step in the biosynthesis, is highly mutated and non-functional.
PROPERTIES OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid, also known as vitamin C, is a water-soluble vitamin that is vital for the body.
As the human body cannot synthesize E 300 Ascorbic Acid, this vitamin must be obtained through food or supplements.
E 300 Ascorbic Acid has strong antioxidant properties and protects cells from the harmful effects of free radicals.
E 300 Ascorbic Acid also plays an important role in collagen production and contributes to strengthening the immune system.
PRESERVATIVE, ANTIOXIDANT AND FOOD SUPPLEMENT OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid acts as a preservative and prevents the browning of fruit juices and fruit, among other things.
Apart from that E 300 Ascorbic Acid is also an important antioxidant.
This means that E 300 Ascorbic Acid helps neutralise harmful substances in your body.
E 300 Ascorbic Acid also promotes digestion and supports your immune system.
E 300 Ascorbic Acid offers natural protection against various diseases.
You can therefore call E 300 Ascorbic Acid a healthy excipient.
E 300 Ascorbic Acid does not contain any flavourings, odours or colourings.
E 300 Ascorbic Acid can be used by vegetarians and vegans.
As a supplement you should take E 300 Ascorbic Acid in a daily quantity of between 2000 - 4000 mg (one teaspoon).
Mix with yoghurt or add to dinner.
THE DIFFERENCE BETWEEN E 300 ASCORBIC ACID AND CITRIC ACID:
Vitamin C, and therefore E 300 Ascorbic Acid, is sometimes confused with citric acid.
Not so strange, because both have a connection with citrus fruit.
In terms of composition, the two also resemble each other.
The difference, however, is that citric acid is produced synthetically and E 300 Ascorbic Acid is not.
Citric acid is used to improve the taste of certain products.
Think, for example, of fruit-flavoured sweets.
E 300 Ascorbic Acid or vitamin C is a preservative, whereas citric acid is a flavour additive.
E 300 Ascorbic Acid is the functional compound of what we know and use as vitamin C.
Citric acid is used in, for example, E 300 Ascorbic Acid tablets, but this is only for flavour and has little nutritional value itself.
A pill from the drugstore or supermarket contains less than 100 mg.
Mix it with the yoghurt at breakfast or add it to dinner.
E 300 Ascorbic Acid is an additive.
E 300 Ascorbic Acid can be produced synthetically from the fermentation and oxidation of glucose.
E 300 Ascorbic Acid is used as a natural anti-oxidant in food and drink products.
E 300 Ascorbic Acid is also added to products like cured meat, breakfast cereals, frozen fish and wine.
HEALTH BENEFITS OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid (E300) helps to reduce wrinkles by aiding to production of collagen in the skin.
E 300 Ascorbic Acid is important for the healthy development of bones, teeth and blood vessels.
E 300 Ascorbic Acid is a white or slightly yellow crystals or powder,a little acid.m.p.190°C-192°C,easily soluble in water,a little soluble in alcohol and uneasily soluble in Ether and chlorofom and other organic solvent.In solid state it is stable in air.
E 300 Ascorbic Acid's water solution is easliy mutated when it meets with air.
E 300 Ascorbic Acid, or vitamin C, a water-soluble dietary supplement.
E 300 Ascorbic Acid is not only an important nutrient but is also used as an antioxidant in various foods.
However, E 300 Ascorbic Acid is not soluble in fat and is unstable under basic conditions.
The name ascorbic means antiscurvy and denotes the ability of ascorbic to combat this disease.
Vitamin C can prevent scurvy, also known as "E 300 Ascorbic Acid."
Over the years, animal experiments and clinical studies have found that E 300 Ascorbic Acid can lower blood cholesterol levels, enhance immunity, increase capillary elasticity, promote healing of wounds and surgical incisions, prevent colds, promote growth and development, and prevent chronic metal poisoning such as mercury and lead.
E 300 Ascorbic Acid is used to prevent aging, prevent tumors, etc.
Therefore, in addition to treatment, there are many people who are consciously taking E 300 Ascorbic Acid, especially some middle-aged and older people prefer to take it regularly or for a long time.
BENEFITS OF E 300 ASCORBIC ACID:
*Flexibility and Durability:
E 300 Ascorbic Acid allows for better dough processing.
*Anti-Staling:
E 300 Ascorbic Acid keeps products fresh longer by reducing retrogradation.
*Cost Advantage:
E 300 Ascorbic Acid offers an economical solution as an alternative to more expensive dough improvers.
ADVANTAGES OF E 300 ASCORBIC ACID:
As a natural antioxidant, E 300 Ascorbic Acid provides protection against oxidation for food products.
E 300 Ascorbic Acid is a versatile component with a wide range of applications.
E 300 Ascorbic Acid is also widely used in different sectors such as healthcare and cosmetics.
MAIN POINTS OF E 300 ASCORBIC ACID:
*E 300 Ascorbic Acid strengthens the immune system.
*Adequate intake supports skin health.
*E 300 Ascorbic Acid has positive effects on weight control.
*E 300 Ascorbic Acid'deficiency leads to various health problems.
SOME POINTS OF E 300 ASCORBIC ACID:
Here are some points that can help you better understand this vitamin:
Benefits of E 300 Ascorbic Acid:
E 300 Ascorbic Acid strengthens the immune system and helps wounds heal quickly.
Where to find E 300 Ascorbic Acid:
E 300 Ascorbic Acid is abundant in fruits such as citrus fruits, green leafy vegetables and red peppers.
Symptoms of vitamin C deficiency:
E 300 Ascorbic Acid manifests itself with symptoms such as fatigue, weakness and weakening of the immune system.
In conclusion, E 300 Ascorbic Acid is a compound that is critical for many biological processes.
E 300 Ascorbic Acid's deficiency can cause serious health problems.
Therefore, E 300 Ascorbic Acid is necessary to ensure that this vitamin is taken in sufficient amounts.
WHAT IS E 300 ASCORBIC ACID AND WHAT IS E 300 ASCORBIC ACID USED FOR?
E 300 Ascorbic Acid, commonly known as Vitamin C, is known by its code E300.
As a food additive, E 300 Ascorbic Acid plays both a preservative and flavor enhancer role in food products.
Although E 300 Ascorbic Acid is found naturally in fruits and vegetables, it is also widely used in processed foods.
SO WHY IS E 300 ASCORBIC ACID SO IMPORTANT?
Because E 300 Ascorbic Acid is a basic antioxidant for the body and plays a critical role in strengthening the immune system.
SOURCES OF E 300 ASCORBIC ACID:
In terms of nutrition, foods that are sources of Vitamin C, such as citrus fruits, strawberries, and green leafy vegetables, contain plenty of E 300 Ascorbic Acid.
Consuming such foods in our daily lives is very beneficial for our health.
HEALTH EFFECTS OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid helps the body fight free radicals, preventing cellular damage.
E 300 Ascorbic Acid also supports skin health and helps wounds heal faster.
Therefore, getting enough E 300 Ascorbic Acid is extremely valuable for improving overall health.
EVOLUTION OF ANIMAL SYNTHESIS OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid is a common enzymatic cofactor in mammals used in the synthesis of collagen, as well as a powerful reducing agent capable of rapidly scavenging a number of reactive oxygen species (ROS).
Given that E 300 Ascorbic Acid has these important functions, it is surprising that the ability to synthesize this molecule has not always been conserved.
In fact, anthropoid primates, Cavia porcellus (guinea pigs), teleost fishes, most bats, and some passerine birds have all independently lost the ability to internally synthesize vitamin C in either the kidney or the liver.
In all of the cases where genomic analysis was done on an E 300 Ascorbic Acid auxotroph, the origin of the change was found to be a result of loss-of-function mutations in the gene that encodes L-gulono-γ-lactone oxidase, the enzyme that catalyzes the last step of the E 300 Ascorbic Acid pathway outlined above.
One explanation for the repeated loss of the ability to synthesize vitamin C is that it was the result of genetic drift; assuming that the diet was rich in vitamin C, natural selection would not act to preserve it.
In the case of the simians, it is thought that the loss of the ability to make vitamin C may have occurred much farther back in evolutionary history than the emergence of humans or even apes, since it evidently occurred soon after the appearance of the first primates, yet sometime after the split of early primates into the two major suborders Haplorrhini (which cannot make vitamin C) and its sister suborder of non-tarsier prosimians, the Strepsirrhini ("wet-nosed" primates), which retained the ability to make vitamin C.
According to molecular clock dating, these two suborder primate branches parted ways about 63 to 60 million years ago.
Approximately three to five million years later (58 million years ago), only a short time afterward from an evolutionary perspective, the infraorder Tarsiiformes, whose only remaining family is that of the tarsier (Tarsiidae), branched off from the other haplorrhines.
Since tarsiers also cannot make vitamin C, this implies the mutation had already occurred, and thus must have occurred between these two marker points (63 to 58 million years ago).
It has also been noted that the loss of the ability to synthesize E 300 Ascorbic Acid strikingly parallels the inability to break down uric acid, also a characteristic of primates.
Uric acid and E 300 Ascorbic Acid are both strong reducing agents.
This has led to the suggestion that, in higher primates, uric acid has taken over some of the functions of E 300 Ascorbic Acid.
PLANT SYNTHESIS OF E 300 ASCORBIC ACID:
There are many different biosynthesis pathways to E 300 Ascorbic Acid in plants.
Most proceed through products of glycolysis and other metabolic pathways.
For example, one pathway utilizes plant cell wall polymers.
The principal plant E 300 Ascorbic Acid biosynthesis pathway seems to be via l-galactose.
The enzyme l-galactose dehydrogenase catalyzes the overall oxidation to the lactone and isomerization of the lactone to the C4-hydroxyl group, resulting in l-galactono-1,4-lactone.
l-Galactono-1,4-lactone then reacts with the mitochondrial flavoenzyme l-galactonolactone dehydrogenase to produce E 300 Ascorbic Acid.
l-E 300 Ascorbic Acid has a negative feedback on l-galactose dehydrogenase in spinach.
E 300 Ascorbic Acid efflux by embryos of dicot plants is a well-established mechanism of iron reduction and a step obligatory for iron uptake.
All plants synthesize E 300 Ascorbic Acid.
E 300 Ascorbic Acid functions as a cofactor for enzymes involved in photosynthesis, synthesis of plant hormones, as an antioxidant and regenerator of other antioxidants.
Plants use multiple pathways to synthesize vitamin C.
The major pathway starts with glucose, fructose or mannose (all simple sugars) and proceeds to l-galactose, l-galactonolactone and E 300 Ascorbic Acid.
This biosynthesis is regulated following a diurnal rhythm.
Enzyme expression peaks in the morning to supporting biosynthesis for when mid-day sunlight intensity demands high E 300 Ascorbic Acid concentrations.
Minor pathways may be specific to certain parts of plants; these can be either identical to the vertebrate pathway (including the GLO enzyme), or start with inositol and get to E 300 Ascorbic Acid via l-galactonic acid to l-galactonolactone.
INDUSTRIAL SYNTHESIS OF E 300 ASCORBIC ACID:
E 300 Ascorbic Acid can be produced from glucose by two main routes.
The no longer utilized Reichstein process, developed in the 1930s, used a single fermentation followed by a purely chemical route.
The modern two-step fermentation process, originally developed in China in the 1960s, uses additional fermentation to replace part of the later chemical stages.
The Reichstein process and the modern two-step fermentation processes both use glucose as the starting material, convert that to sorbitol, and then to sorbose using fermentation.
The two-step fermentation process then converts sorbose to 2-keto-l-gulonic acid (KGA) through another fermentation step, avoiding an extra intermediate.
Both processes yield approximately 60% E 300 Ascorbic Acid from the glucose starting point.
Researchers are exploring means for one-step fermentation.
HISTORY OF E 300 ASCORBIC ACID:
Scurvy was known to Hippocrates, described in book two of his Prorrheticorum and in his Liber de internis affectionibus, and cited by James Lind.
Symptoms of scurvy were also described by Pliny the Elder: (i) Pliny. "49". Naturalis historiae. Vol. 3.; and (ii) Strabo, in Geographicorum, book 16, cited in the 1881 International Encyclopedia of Surgery
*Scurvy at sea
In the 1497 expedition of Vasco da Gama, the curative effects of citrus fruit were known.
In the 1500s, Portuguese sailors put in to the island of Saint Helena to avail themselves of planted vegetable gardens and wild-growing fruit trees.
Authorities occasionally recommended plant food to prevent scurvy during long sea voyages.
John Woodall, the first surgeon to the British East India Company, recommended the preventive and curative use of lemon juice in his 1617 book, The Surgeon's Mate.
In 1734, the Dutch writer Johann Bachstrom gave the firm opinion, "scurvy is solely owing to a total abstinence from fresh vegetable food, and greens."
Scurvy had long been a principal killer of sailors during the long sea voyages.
According to Jonathan Lamb, "In 1499, Vasco da Gama lost 116 of his crew of 170; In 1520, Magellan lost 208 out of 230; ... all mainly to scurvy.
The first attempt to give scientific basis for the cause of this disease was by a ship's surgeon in the Royal Navy, James Lind.
While at sea in May 1747, Lind provided some crew members with two oranges and one lemon per day, in addition to normal rations, while others continued on cider, vinegar, sulfuric acid or seawater, along with their normal rations, in one of the world's first controlled experiments.
The results showed that citrus fruits prevented the disease.
Lind published his work in 1753 in his Treatise on the Scurvy.
Fresh fruit was expensive to keep on board, whereas boiling it down to juice allowed easy storage, but destroyed the vitamin (especially if it was boiled in copper kettles).
It was 1796 before the British navy adopted lemon juice as standard issue at sea.
In 1845, ships in the West Indies were provided with lime juice instead, and in 1860 lime juice was used throughout the Royal Navy, giving rise to the American use of the nickname "limey" for the British.
Captain James Cook had previously demonstrated the advantages of carrying "Sour krout" on board by taking his crew on a 1772–75 Pacific Ocean voyage without losing any of his men to scurvy.
For his report on his methods the British Royal Society awarded him the Copley Medal in 1776.
The name antiscorbutic was used in the eighteenth and nineteenth centuries for foods known to prevent scurvy.
These foods included lemons, limes, oranges, sauerkraut, cabbage, malt, and portable soup.
In 1928, the Canadian Arctic anthropologist Vilhjalmur Stefansson showed that the Inuit avoided scurvy on a diet largely of raw meat.
Later studies on traditional food diets of the Yukon First Nations, Dene, Inuit, and Métis of Northern Canada showed that their daily intake of E 300 Ascorbic Acid averaged between 52 and 62 mg/day.
E 300 Ascorbic Acid was discovered in 1912, isolated in 1928 and synthesized in 1933, making it the first vitamin to be synthesized.
Shortly thereafter Tadeus Reichstein succeeded in synthesizing the vitamin in bulk by what is now called the Reichstein process.
This made possible the inexpensive mass-production of vitamin C.
In 1934, Hoffmann–La Roche bought the Reichstein process patent, trademarked synthetic vitamin C under the brand name Redoxon, and began to market it as a dietary supplement.
In 1912, the Polish biochemist Casimir Funk developed the concept of vitamins.
One of these was thought to be the anti-scorbutic factor.
In 1928, this was referred to as "water-soluble C", although its chemical structure had not been determined.
From 1928 to 1932, Albert Szent-Györgyi and Joseph L. Svirbely's Hungarian team, and Charles Glen King's American team, identified the anti-scorbutic factor.
Szent-Györgyi isolated hexuronic acid from animal adrenal glands, and suspected it to be the antiscorbutic factor.
In late 1931, Szent-Györgyi gave Svirbely the last of his adrenal-derived hexuronic acid with the suggestion that it might be the anti-scorbutic factor.
By the spring of 1932, King's laboratory had proven this, but published the result without giving Szent-Györgyi credit for it.
This led to a bitter dispute over priority.
In 1933, Walter Norman Haworth chemically identified the vitamin as l-hexuronic acid, proving this by synthesis in 1933.
Haworth and Szent-Györgyi proposed that L-hexuronic acid be named a-scorbic acid, and chemically l-E 300 Ascorbic Acid, in honor of its activity against scurvy.
The term's etymology is from Latin, "a-" meaning away, or off from, while -scorbic is from Medieval Latin scorbuticus (pertaining to scurvy), cognate with Old Norse skyrbjugr, French scorbut, Dutch scheurbuik and Low German scharbock.
Partly for this discovery, Szent-Györgyi was awarded the 1937 Nobel Prize in Medicine, and Haworth shared that year's Nobel Prize in Chemistry.
In 1957, J. J. Burns showed that some mammals are susceptible to scurvy as their liver does not produce the enzyme l-gulonolactone oxidase, the last of the chain of four enzymes that synthesize vitamin C.
American biochemist Irwin Stone was the first to exploit vitamin C for its food preservative properties.
He later developed the idea that humans possess a mutated form of the l-gulonolactone oxidase coding gene.
Stone introduced Linus Pauling to the theory that humans needed to consume vitamin C in quantities far higher than what was considered a recommended daily intake in order to optimize health.
In 2008, researchers discovered that in humans and other primates the red blood cells have evolved a mechanism to more efficiently utilize the vitamin C present in the body by recycling oxidized l-dehydroascorbic acid (DHA) back into E 300 Ascorbic Acid for reuse by the body.
The mechanism was not found to be present in mammals that synthesize their own vitamin C.
HISTORY OF LARGE DOSE THERAPIES OF E 300 ASCORBIC ACID:
Vitamin C megadosage is a term describing the consumption or injection of vitamin C in doses comparable to or higher than the amounts produced by the livers of mammals which are able to synthesize vitamin C.
An argument for this, although not the actual term, was described in 1970 in an article by Linus Pauling.
Briefly, his position was that for optimal health, humans should be consuming at least 2,300 mg/day to compensate for the inability to synthesize vitamin C.
The recommendation also fell into the consumption range for gorillas — a non-synthesizing near-relative to humans.
A second argument for high intake is that serum E 300 Ascorbic Acid concentrations increase as intake increases until it plateaus at about 190 to 200 micromoles per liter (μmol/L) once consumption exceeds 1,250 milligrams.
As noted, government recommendations are a range of 40 to 110 mg/day and normal plasma is approximately 50 μmol/L, so "normal" is about 25% of what can be achieved when oral consumption is in the proposed megadose range.
Pauling popularized the concept of high dose vitamin C as prevention and treatment of the common cold in 1970.
A few years later he proposed that vitamin C would prevent cardiovascular disease, and that 10 grams/day, initially administered intravenously and thereafter orally, would cure late-stage cancer.
Mega-dosing with E 300 Ascorbic Acid has other champions, among them chemist Irwin Stone and the controversial Matthias Rath and Patrick Holford, who both have been accused of making unsubstantiated treatment claims for treating cancer and HIV infection.
The idea that large amounts of intravenous E 300 Ascorbic Acid can be used to treat late-stage cancer or ameliorate the toxicity of chemotherapy is — some forty years after Pauling's seminal paper — still considered unproven and still in need of high quality research.
PHYSICAL and CHEMICAL PROPERTIES of E 300 ASCORBIC ACID:
Formula: C6H8O6
Molar mass: 176.124 g·mol−1
Density: 1.694 g/cm3
Melting point: 190 to 192 °C (374 to 378 °F)
Boiling point: 552.7 °C (1,026.9 °F)
CAS Number: 50-81-7
as salt: 134-03-2
E number: E300 (antioxidants, ...)
Product Name: Ascorbic Acid (Vitamin C) E300
Chemical Name: L-Ascorbic Acid, Vitamin C, Ascorvit, Vicomin C
Chemical Formula: H₂C₆H₆O₆
Appearance: White crystalline or powder form, with a slightly acidic odor.
Chemical Name: L-Ascorbic Acid
IUPAC Name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
CAS Number: 50-81-7 2
EC Number: 200-066-2 3
E Number: E300
Molecular Formula: C₆H₈O₆
Molecular Weight: 176.12 g/mol
Appearance: White to off-white crystalline powder
Odour: Odourless
Taste: Sour
Solubility: Highly soluble in water (330 g/L at 24°C); slightly soluble in ethanol (20 g/L at 20°C)
pH (50 g/L solution): Approximately 2.2–2.5
Density: ~1.65 g/cm³
Melting Point: 190–192°C (decomposes)
Stability: Sensitive to light, heat, and air; degrades upon exposure
INCI: ASCORBIC ACID
CAS: 50-81-7
Molar mass: 176,12 g/mol
Density: 1,694 g/cm3
Solubility: In water 58 g/100 ml
Chemical Formula: C₆H₈O₆
Molecular Weight: 176.12 g/mol
Physical State: White or slightly yellow crystalline powder
Melting Point: 190-194°C (decomposes)
Solubility: Highly soluble in water
pH: 3.59 (1 mM solution)
Molecular Formula (Ascorbic Acid): C6H8O6
Molecular Weight: 176.174 g/mol
Chemical Name: Ascorbic Acid (Vitamin C)
CAS Number: 50-81-7
FIRST AID MEASURES of E 300 ASCORBIC ACID:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of E 300 ASCORBIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of E 300 ASCORBIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of E 300 ASCORBIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of E 300 ASCORBIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of E 300 ASCORBIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available