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E 954 Sodium Saccharin, also called saccharine, benzosulfimide, or used in saccharin sodium or saccharin calcium forms, is a non-nutritive artificial sweetener.
E 954 Sodium Saccharin is a sultam that is about 500 times sweeter than sucrose, but has a bitter or metallic aftertaste, especially at high concentrations.
E 954 Sodium Saccharin is used to sweeten products, such as drinks, candies, baked goods, tobacco products, excipients, and for masking the bitter taste of some medicines.
CAS Number: 128-44-9
Molecular Formula: C7H5NNaO3S
Molecular Weight: 206.17
EINECS Number: 204-886-1
Synonyms: SACCHARIN SODIUM, 128-44-9, Sodium saccharin, Saccharin, sodium, Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide, Saccharin sodium anhydrous, Sodium saccharine, Sodium saccharinate, Saccharinnatrium, Sucra, Soluble gluside, Crystallose, Kristallose, Willosetten, Dagutan, Madhurin, Sucromat, Saccharoidum natricum, Saccharin sodium, anhydrous, Sodium benzosulphimide, Sodium saccharin, anhydrous, Saccharine sodium salt, Saccharin soluble, Sodium saccharide, Saccharine soluble, Sodium o-benzosulphimide, FEMA No. 2997, Sodium 2-benzosulphimide, Cristallose, Saccharin sodium salt, Saccharin, sodium salt, Sodium o-benzosulfimide, CCRIS 706, Soluble saccharin, Benzoic acid sulfimide, sodium, Sulphobenzoic imide, sodium salt, NSC 4867, EINECS 204-886-1, Saccharin (sodium), 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt, DTXSID5021253, Saccharin, sodium salt (C7H5NO3S.xNa), 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt, o-Sulfonbenzoic acid imide sodium salt, Hermesetas original (TN), Sodium 1,2 benzisothiazolin-3-one 1,1-dioxide, Sodium 1,2 benzisothiazolin-3-one-1,1-dioxide, Sodium 1,2-benzisothiazolin-3-one 1,1-dioxide, I4807BK602, Sodium 1,2-benzisothiazol-3(2H)-one, 1,1-dioxide, Artificial sweetening substanz gendorf 450, 1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium salt, SODIUM SACCHARIN [FCC], DTXCID201253, Saccharin sodium dihydrate, CHEBI:32112, EC 204-886-1, SACCHARIN SODIUM [WHO-DD], SACCHARIN SODIUM [WHO-IP], NSC-4867, Sucredulcor, SACCHARIN SODIUM SALT [FHFI], 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide sodium salt, SACCHARIN SODIUM [EP MONOGRAPH], SACCHARIN SODIUM ANHYDROUS [II], o-Benzoic Sulfimide Sodium Salt, 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one, sodium salt, 1,2-Benzisothiazolin-3-one, 1,1-dioxide, sodium deriv., Gluside, Soluble, SACCHARINUM NATRICUM [WHO-IP LATIN], SACCHARIN SODIUM, ANHYDROUS [WHO-IP], Benzosulphinide Sodium, 6155-57-3, Saccharin sodium hydrate, sodium 3-oxo-3H-1,2-benzisothiazol-2-ide 1,1-dioxide, Saccharin sodium, dihydrate, 1,2-BENZISOTHIAZOLIN-3-ONE 1,1-DIOXIDE SODIUM SALT, sodium 1,1,3-trioxo-2,3-dihydro-1??,2-benzothiazol-2-ide, o-Sulfobenzimide sodium salt, 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1), sodium 1,1,3-trioxo-2,3-dihydro-1lambda6,2-benzothiazol-2-ide, Saccharinum natricum, dihydrate, INS NO.954(IV), SACCHARIN SODIUM (EP MONOGRAPH), SACCHARIN SODIUM ANHYDROUS (II), SACCHARIN SODIUM [VANDF], DTXSID60904757, NSC4867, SACCHARIN SODIUM (USP-RS), SACCHARIN SODIUM [USP-RS], o-Sulfobenzimide sodium salt dihydrate, SACCHARIN SODIUM HYDRATE [JAN], SACCHARIN SODIUM SALT DIHYDRATE, SACCHARIN SODIUM DIHYDRATE (II), SACCHARIN SODIUM DIHYDRATE [II], SACCHARIN SODIUM (USP MONOGRAPH), SACCHARIN SODIUM [USP MONOGRAPH], Saccharin, sodium deriv., SACCHARIN SODIUM SALT DIHYDRATE [MI], SACCHARIN SODIUM, DIHYDRATE [WHO-IP], o-Benzoylsulfimide sodium salt, 2-Sodio-1,2-benzo(d)isothiazol-3(2H)-one 1,1-dioxide dihydrate, 2-Sodio-1,2-benzo[d]isothiazol-3(2H)-one 1,1-dioxide dihydrate, UNII-I4807BK602, SACCHARINUM NATRICUM, DIHYDRATE [WHO-IP LATIN], Hermesetas original, Sodium obenzosulfimide, Sodium obenzosulphimide, Sodium 2benzosulphimide, Saccharin - sodium salt, C7H4NNaO3S, artificial sweetening substance gendorf 450, SACCHARINE, SOLUBLE, SACCHARINUM NATRICUM, SCHEMBL3372, sodium 1,2-benzisothiasolin-3-one-1,1-dioxide, sodium;1,1-dioxo-1,2-benzothiazol-2-id-3-one, SODIUM SACCHARIN [INCI], CHEMBL2219743, HY-B1390A, Saccharin sodium hydrate (JP17), DTXCID001333870, Tox21_200515, oSulfonbenzoic acid imide sodium salt, AKOS000121310, AKOS004110724, NCGC00258069-01, AC-11597, AS-69031, CAS-128-44-9, Sodium 1,2 benzisothiazolin3one1,1dioxide, Sodium 1,2benzisothiazolin3one 1,1dioxide, DB-041898, B0131, CS-0013680, NS00100138, Sodium 1,2-benzisothiazolin3one 1,1dioxide, EN300-20159, D08500, Sodium 1,2benzisothiazol3(2H)one, 1,1dioxide, 1,1Dioxide1,2benzisothiazol3(2H)one, sodium salt, 1,2Benzisothiazol-3(2H)one, 1,1-dioxide, sodium salt, 1,2Benzisothiazolin-3one, 1,1-dioxide, sodium deriv., 1,2Benzisothiazol3(2H)one, 1,1-dioxide, sodium salt, Q27094367, 612-173-5, 1,2-Benzothiazol-3(2H)-one 1,1-dioxide sodium salt;Sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one;2-Sodio-1,2-benzisothiazol-3(2H)-one 1,1-dioxide;o-Benzoic acid sulfimide sodium;204-886-1;kristallose;madhurin;o-sulfonbenzoicacidimidesodiumsalt
E 954 Sodium Saccharin appears as white crystals and is odorless.
E 954 Sodium Saccharin is an artificial sweetener that has been used in food and beverage products for over a century.
It is one of the oldest artificial sweeteners and is approximately 300 to 500 times sweeter than sucrose (table sugar), making it a very effective and low-calorie option for sweetening various products.
E 954 Sodium Saccharin is the sodium salt form of saccharin, which is a benzoic sulfonamide compound.
E 954 Sodium Saccharin itself is a white, crystalline powder with a bitter aftertaste, but when combined with sodium, it becomes more stable and suitable for use in food and drinks.
E 954 Sodium Saccharin is typically used in combination with other sweeteners to improve taste and reduce the aftertaste that some artificial sweeteners may have.
It is highly resistant to heat, making it suitable for use in baked goods and cooking.
This heat stability, along with its high sweetness intensity, makes it a popular choice for sugar-free and dietetic products, such as diet sodas, sugar-free gum, sugar-free candy, and sugar substitutes for coffee and tea.
E 954 Sodium Saccharin is a type of artificial or nonnutritive sweetener.
E 954 Sodium Saccharin is 200 to 700 times sweeter than sucrose but has a bitter aftertaste.
E 954 Sodium Saccharin and its salts do not occur naturally. Saccharin sodium is used in the production of various foods and pharmaceutical products including soft drinks, candy, biscuits, jams, chewing gum, tinned fruit, medicine and toothpaste.
E 954 Sodium Saccharin is a crystalline solid with a sweet taste (500 times sweeter than sugar).
E 954 Sodium Saccharin is commercially available in three forms : acid saccharin , sodium saccharin , and calcium saccharin .
These forms have been variously determined to be 200-800 times sweeter than sucrose , depending on the saccharin concentration.
E 954 Sodium Saccharin sodium salt has no odor, but has an intensly sweet taste. Aqueous solution is neutral or alkaline to litmus, but not alkaline to phenolphthalein.
E 954 Sodium Saccharin is intended to be used in feed, premixtures and water for drinking for piglets (suckling and weaned piglets), pigs for fattening and calves for rearing up to 4 months and for calves for fattening up to 6 months, with levels up to 150 mg/kg of complete feedingstuffs and water for drinking.
E 954 Sodium Saccharin is the oldest artificial sweetener, and was discovered in 1879.
The compound is prepared through reacting methyl anthranilate with nitrous acid sulfur dioxide, chlorine, and ammonia.
E 954 Sodium Saccharin is about 300 times sweeter than sucrose and is considered to be one of the most important and widely used sweeteners worldwide.
E 954 Sodium Saccharin is a water-soluble acid with a pKa of 1.8.
Its absorption is increased in animal species with lower stomach pH, such as rabbits and humans, relative to other mammals with higher stomach pHs such as rats.
Other forms of saccharin that are consumed include: calcium saccharin, potassium saccharin, and acid saccharin.
E 954 Sodium Saccharin is used most often due to its greater palatability.
E 954 Sodium Saccharin, in addition to being used as a table-top sweetener, is commonly used in soft drinks, baked foods, jams, canned fruit, candy, dessert toppings, and chewing gum.
Since saccharin’s sweetening power is not reduced when heated, it is an excellent candidate as an additive in low-calorie and sugar-free products.
E 954 Sodium Saccharin is chemically synthesised.
The manufacturing process described by the applicant uses either phthalic anhydride or methyl anthranilate as starting material.
Methyl anthranilate is diazotized to form 2-carbomethoxybenzene-diazonium chloride.
Sulfonation followed by oxidation yields 2-carbomethoxybenzenesulfonyl chloride.
Amidation of the sulfonylchloride followed by acidification will form insoluble acid saccharin.
Subsequent addition of sodium hydroxide produces the soluble saccharin sodium.
E 954 Sodium Saccharin derives its name from the word "saccharine", meaning "sugary".
The word saccharine is used figuratively, often in a derogative sense, to describe something "unpleasantly over-polite" or "overly sweet".
Both words are derived from the Greek word σάκχαρον (sakkharon) meaning "gravel".
E 954 Sodium Saccharin similarly, saccharose is an obsolete name for sucrose (table sugar).
E 954 Sodium Saccharin does not react chemically with other food ingredients; as such, it stores well. Blends of saccharin with other sweeteners are often used to compensate for each sweetener's weaknesses and faults.
A 10:1 cyclamate–saccharin blend is common in countries where both these sweeteners are legal; in this blend, each sweetener masks the other's offtaste.
E 954 Sodium Saccharin is often used with aspartame in diet carbonated soft drinks, so some sweetness remains should the fountain syrup be stored beyond aspartame's relatively short shelf life.
In its acid form, saccharin is not water-soluble.
The form used as an artificial sweetener is usually its sodium salt.
The calcium salt is also sometimes used, especially by people restricting their dietary sodium intake. Both salts are highly water-soluble: 0.67 g/ml in water at room temperature.
E 954 Sodium Saccharin is used as a sweetening and avoring agent in food products and beverages.
E 954 Sodium Saccharin is also used for masking unpleasant taste in pharmaceutical formulations such as tablets and powders.
Its sweetening power is approximately 300 times more than sucrose.
E 954 Sodium Saccharin may be used as a reference standard for the determination of the analyte in pharmaceuticals by continuous ow spectrophotometric technique.
These Secondary Standards are qualied as Certied Reference Materials.
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method
development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
E 954 Sodium Saccharin, is an articial sweetener which is about 400 times sweeter than sugar.
E 954 Sodium Saccharin is widely used in the food industry i.a. in soft drinks and sugar-free foods.
E 954 Sodium Saccharin is chemically prepared by the oxidation of o-toluenesulfonamide to form insoluble odourless white crystals.
Additionally, E 954 Sodium Saccharin is used to sweeten products such as drinks, candies, cookies, and medicines.
E 954 Sodium Saccharin has E number 954 and is approved to use as food additive in EU.
E 954 Sodium Saccharin, CAS# 128-44-9, is an articial sweetener, available as white crystal or powder.
As the rst articial sweetener discovered, E 954 Sodium Saccharin is still widely used as sweetener in food and beverage.
E 954 Sodium Saccharin is widely accepted as safe food additive in many countries with E number E954.
The pharmaceutical industry uses E 954 Sodium Saccharin as a coating on drugs.
Chewable multivitamin and calcium tablets often contain E 954 Sodium Saccharin to improve their taste.
E 954 Sodium Saccharin is also employed in the manufacture of toothpastes, personal health care products and cosmetics.
E 954 Sodium Saccharin can be used in toothpaste, mouthwash and used as a non-nutritive sweetener and stabilizer in a variety of food and drinks
E 954 Sodium Saccharin is an articial sweetener with eectively no nutritional value.
Furthermore, E 954 (Saccharin sodium) is about 550 times as sweet as sucrose but has a bitter or metallic aftertaste, especially at high concentrations.
E 954 (Saccharin sodium) is used to sweeten products such as drinks, candies, cookies, and especially for masking bitter taste of some medicines.
Saccharin derives its name from the word "saccharine", meaning "sugary".
The word saccharine is used guratively, often in a derogative sense, to describe something "unpleasantly over-polite" or "overly sweet".
Both words are derived from the Greek word σάκχαρον (sakkharon) meaning "gravel".
Similarly, E 954 Sodium Saccharin is an obsolete name for sucrose (table sugar).
E 954 Sodium Saccharin or saccharine, the oldest but controversial articial sweetener, which has been used as a low-calorie sweetener and sugar substitute in food and beverage for more than 100 years with the European food additive number E954.
With the advantage of lower price and heat stability (250°C, thus suitable for cooking and baking), E 954 Sodium Saccharin was widely used in food and beverage.
However, its food uses are not as popular as E 954 Sodium Saccharin used to be, but its market in toothpaste is big.
E 954 Sodium Saccharin is available in anhydrous and dihydrated forms, exist in granular, powder, and liquid appearance.
Its granular is often used in situations where E 954 Sodium Saccharin needs to be dissolved, and powder is usually used in dry mixes and pharmaceuticals.
E 954 Sodium Saccharin is one of the oldest articial sweeteners on the market.
In fact, E 954 Sodium Saccharin has been used to sweeten foods and drinks for over 100 years.
However, E 954 Sodium Saccharin wasn’t until the ’60s and ’70s that it became popular as a sugar replacement.
Some say that replacing sugar with E 954 Sodium Saccharin benets weight loss, diabetes, and dental health.
Others are skeptical about the safety of all articial sweeteners, including E 954 (Saccharin sodium).
E 954 Sodium Saccharin is a non-nutritive or articial sweetener.
E 954 Sodium Saccharin is made in a laboratory by oxidizing the chemicals o-toluene sulfonamide or phthalic anhydride.
E 954 Sodium Saccharin looks like white, crystalline powder.
E 954 Sodium Saccharin is commonly used as a sugar substitute because it doesn’t contain calories or carbs.
Humans can’t break down E 954 Sodium Saccharin leaves your body unchanged.
E 954 Sodium Saccharin is around 300–400 times sweeter than regular sugar, so you only need a small amount to get a sweet taste.
However, E 954 Sodium Saccharin can have an unpleasant, bitter aftertaste.
This is why E 954 Sodium Saccharin is often mixed with other low or zero-calorie sweeteners.
For example, E 954 Sodium Saccharin is sometimes combined with aspartame, another low-calorie sweetener commonly found in carbonated diet drinks.
Food manufacturers often use E 954 Sodium Saccharin because it’s fairly stable and has a long shelf life.
E 954 Sodium Saccharin is safe to consume even after years of storage.
In addition to carbonated diet drinks, E 954 Sodium Saccharin is used to sweeten low-calorie candies, jams, jellies, and cookies.
E 954 Sodium Saccharin is also used in many medicines.
E 954 Sodium Saccharin can be used similarly to table sugar to sprinkle onto food, such as cereal or fruit, or used as a sugar substitute in coee or when baking.
E 954 Sodium Saccharin is a white odorless sweet powder that exhibits excellent synergistic properties when blended with other high intensity sweeteners.
Moreover, E 954 Sodium Saccharin is also commercially available in Calcium and Acid forms.
E 954 Sodium Saccharin is freely soluble in water and is approximately 300-500 times sweeter than sucrose.
E 954 Sodium Saccharin is one of the most common and well-known synthetic sweeteners besides Sucralose and Acesulfame K.
Synthetic sweeteners are widely used in the food industry, and can appear on virtually any food.
In addition to the main eect of creating sweetness, E 954 Sodium Saccharin also acts as a sweetener for products and does not contain calories.
Melting point: >300°C
Density: 1.69[at 20℃]
vapor pressure: 0Pa at 25℃
FEMA: 2997 | SACCHARINE, SODIUM SALT
storage temp.: 0-6°C
solubility: H2O: 1 M at 20 °C, clear, colorless; sparingly soluble in ethanol.
pka: 0.003-0.003[at 20 ℃]
form: Solid
color: White crystals or a white, crystalline efflorescent powder
Odor: odourless or with a faint, aromatic odour
Water Solubility: >=10 g/100 mL at 20 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: WINXNKPZLFISPD-UHFFFAOYSA-M
LogP: -2.84-0.11 at 25℃
E 954 Sodium Saccharin has played a significant role in the world of artificial sweeteners for over a century.
Originally discovered in 1879, E 954 Sodium Saccharin is known for being much sweeter than sugar while containing no calories.
E 954 Sodium Saccharin is a food additive with a code E954.
Its widespread use in various food and beverage products highlights its importance in the quest for alternatives to sugar in the diet.
The appeal of E 954 Sodium Saccharin lies in its efficiency and versatility. Used in everything from soft drinks to toothpaste, it provides a sweet taste without adding to calorie counts.
E 954 Sodium Saccharin offers a solution for those seeking to reduce sugar intake without sacrificing sweetness.
Its safety has been extensively studied, leading to its approval by major health organizations.
Though past controversies over potential health risks have led to some caution, current scientific consensus supports its safety when consumed within recommended limits.
This history makes sodium saccharin a compelling subject for those interested in food science and nutrition.
E 954 Sodium Saccharin occurs as a white, odorless or faintly aromatic, efflorescent, crystalline powder.
It has an intensely sweet taste, with a metallic or bitter aftertaste that at normal levels of use can be detected by approximately 25% of the population.
The aftertaste can be masked by blending E 954 Sodium Saccharin with other sweeteners. Saccharin sodium can contain variable amounts of water.
E 954 Sodium Saccharin and toxicity are arguable.
Throughout the 1960s, various studies suggested that saccharin might be an animal carcinogen.
Most publications reference that saccharin increases the rate of bladder cancer in rats fed with large doses.
A few epidemiological studies also found relationships between saccharin and bladder cancer risk in humans, but the majority of studies found no association between saccharin and cancer.
E 954 Sodium Saccharin has shown tumorigenic effects in rats.
The compound was reported to produce hyperplastic response within a relatively short period of time when administered at high doses (≥2.5%).
E 954 Sodium Saccharin consumption has been associated with adverse effects on most of the biochemical and hematological blood indices in rats.
Chronic saccharin intake affects biochemical parameters, and reported findings reflect various metabolic, hormonal, and neural responses in male and female rats resulting from the prolonged use of this sweetener after a single dose in drinking water.
Consumption of large amounts of saccharin (135 mg) may result in hypoglycemia, reduced hyperinsulinemia, decreased insulin resistance, and improved glycemic control in hyperglycemic obese mice.
E 954 Sodium Saccharin is a flavoring agent and non-nutritive sweetener.
It is a salt of saccharin widely used as sweetener in food and beverage.
As a high-intensity sweetener, Saccharin Sodium can be used in a wide variety of industries including: food production, beverage, cosmetics, agriculture/animal feed, and various other industries.
E 954 Sodium Saccharin can be used for the purification of recombinant polypeptides, such as antibodies.
E 954 Sodium Saccharin appears as odorless white crystals or crystalline powder.
Aqueous solution is neutral or alkaline to litmus, but not alkaline to phenolphthalein.
The information provided has to do, primarily, with the manufacturing of saccharin.
E 954 Sodium Saccharin has been used as a nonnutritive sweetening agent.
At one point the United States consumption pattern for all forms of saccharin has been estimated as 45% in soft drinks; 18% in tabletop sweeteners; 14% in fruits, juices, sweets, chew- ing gum, and jellies; 10% in cosmetics and oral hygiene products; 7% in drugs, such as coating on pills; 2% in tobacco; 2% in electroplating; and 2% for miscellaneous uses.
Human exposure to saccharin occurs primarily through ingestion because of its use in many dietic foods and drinks and some personal hygiene products, including toothpastes and mouthwashes.
The general public is exposed to saccharin, especially by persons required to reduce sugar intake.
E 954 Sodium Saccharin is commonly used in personal care products such as toothpastes and mouthwash as a sweetening agent, which will not cause tooth decay.
E 954 Sodium Saccharin in the products with the functions of better taste, good stability and not contributing to the development of cavities.
Also, E 954 Sodium Saccharin is in some toothpaste, E 954 (Saccharin sodium) is used as a avor/sweetener to make uoride and abrasives in toothpaste taste delicious.
E 954 Sodium Saccharin is a sugar substitute for toothpaste, mouthwash, beverages, table-top sweeteners, confectionery, electroplating and etc.
From our observing, there is lot of toothpaste that contains E 954 (Saccharin sodium).
The use quantity in toothpaste is more than 50% of its total consumption in the market.
E 954 Sodium Saccharin does not promote tooth decay in toothpaste while sugar can.
Toothpaste must have thickeners to stay on the toothbrush and squeeze out of the tube.
E 954 Sodium Saccharin must have detergents to remove fatty lms, and water softeners to make the detergents work better, and sweeteners, preferably non-nutritive, so bacteria are not encouraged.
E 954 Sodium Saccharin is stable under the normal range of conditions employed in formulations.
Only when it is exposed to a high temperature (125℃) at a low pH (pH 2) for over 1 hour does significant decomposition occur.
The 84% grade is the most stable form of saccharin sodium since the 76% form will dry further under ambient conditions.
Solutions for injection can be sterilized by autoclave.
Dust may form explosive mixture with air.
Incompatible with strong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides.
Consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Generators of waste containing this contami- nant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal.
E 954 Sodium Saccharin continues to be important for a wide range of low-calorie and sugar-free food & beverage applications.
E 954 Sodium Saccharin is used in such products as soft drinks, tabletop sweeteners, baked goods, jams, chewing gum, canned fruit, candy, dessert toppings, and salad dressings.
Additionally, personal care products such as toothpaste, mouthwash, hygiene/cosmetic products, vitamins, and pharmaceuticals contain E 954 Sodium Saccharin.
E 954 Sodium Saccharin and other low-calorie sweeteners, such as aspartame, acesulfame potassium, neotame, and sucralose, allows manufacturers to utilize a “multiple sweetener approach” — using the most appropriate sweetener, or combination of sweeteners, for a given product.
Blending a variety of low-calorie sweeteners provides products with increased stability, improved taste, lower production costs, and more choices for the consumer.
Additionally, blendingE 954 Sodium Saccharin with one or more low calorie sweeteners can result in sweetness synergy (the resulting sweetness is greater than the sum of the sweetness of the individual sweeteners), which can decrease the total amount of sweetener.
E 954 Sodium Saccharin is stable when heated, even in the presence of acids, does not react chemically with other food ingredients, and stores well.
Although sodium saccharin has been used in many countries, it has been the subject of some controversy and health debates over the years.
Early studies in the 1970s raised concerns about its potential link to cancer in laboratory animals, leading to the temporary ban of saccharin in certain countries.
However, more recent studies and reviews by health authorities, including the U.S. Food and Drug Administration (FDA), the European Food Safety Authority (EFSA), and the World Health Organization (WHO), have concluded that saccharin is safe for human consumption when consumed within acceptable limits.
E 954 Sodium Saccharin was delisted as a potential carcinogen by the U.S. National Toxicology Program in the 2000s, and it is now generally recognized as a safe additive for food and drink.
E 954 Sodium Saccharin is used as a non-caloric sweetener, making it a popular choice for people who are looking to reduce calorie intake, manage weight, or control blood sugar levels, particularly for those with diabetes.
The European Union has set a maximum allowable intake for E 954 Sodium Saccharin in food products, which ensures its safe consumption without exceeding the recommended limits.
Despite its long history of use, saccharin is sometimes avoided by people who prefer natural or less controversial sweeteners.
Nonetheless, E 954 sodium saccharin remains a staple in the world of artificial sweeteners due to its efficacy, cost-effectiveness, and stability.
Uses Of E 954 Sodium Saccharin:
E 954 Sodium Saccharin is the salt most frequently used in formulating soluble forms of this sweetening agent.
It can be used in toothpaste, mouthwash, diet soft drinks, syrups, baked goods, ice cream, and other sweet foods and drinks.
While it is certainly most famously used in food products, sodium saccharin is also used in the chemical and agricultural industries as an aid in the production of herbicides and pesticides.
E 954 Sodium Saccharin is also used as part of a solution used to coat metals, such as gold and nickel.
Major application of Sodium saccharine is the food industry as an additive in different products.
E 954 Sodium Saccharin is used as a low calorie sweetener and stabilizer in a variety of food and drinks.
In bakeries it is used to sweeten baked goods, breads, cookies and muffins.
Due to its rapidly dissolving nature in water, it is used as an artificial sweetener in carbonated beverages and sodas.
E 954 Sodium Saccharin is a flavoring agent and non-nutritive sweetener.
E 954 Sodium Saccharin is a salt of saccharin widely used as sweetener in food and beverage.
As a high-intensity sweetener, E 954 Sodium Saccharin can be used in a wide variety of industries including: food production, beverage, cosmetics, agriculture/animal feed, and various other industries.
E 954 Sodium Saccharin can be used for the purification of recombinant polypeptides, such as antibodies.
E 954 Sodium Saccharin is an intense sweetening agent used in beverages, food products, table-top sweeteners, and pharmaceutical formulations such as tablets, powders, medicated confectionery, gels, suspensions, liquids, and mouthwashes.
It is also used in vitamin preparations.
E 954 Sodium Saccharin is considerably more soluble in water than saccharin, and is more frequently used in pharmaceutical formulations.
Its sweetening power is approximately 300–600 times that of sucrose.
E 954 Sodium Saccharin enhances flavor systems and may be used to mask some unpleasant taste characteristics.
Injection of E 954 Sodium Saccharin has been used to measure the armto- tongue circulation time.
One of the most common uses of sodium saccharin is in diet sodas, sugar-free soft drinks, and low-calorie beverages.
E 954 Sodium Saccharin is often combined with other sweeteners, such as aspartame or sucralose, to create a sweet taste while maintaining a zero-calorie or low-calorie profile.
This allows consumers to enjoy their favorite drinks without worrying about the sugar content or associated calories.
E 954 Sodium Saccharin is often chosen because of its heat stability, which means it retains sweetness even when the beverage is carbonated or exposed to heat.
E 954 Sodium Saccharin is frequently used in sugar-free gums, chewing gums, and candies.
As an intensely sweet compound, it allows manufacturers to create sugar-free options that still provide the desired sweet flavor without contributing to cavity formation or tooth decay.
E 954 Sodium Saccharin is particularly popular in sugar-free mints and sugar-free hard candies, which are marketed to people who are trying to avoid sugar for oral health reasons or those with diabetes.
E 954 Sodium Saccharin is often included in tabletop sweeteners, commonly used as a sugar substitute for coffee, tea, or other beverages.
As an easy-to-use and affordable alternative to sugar, it allows consumers to enjoy sweetened drinks without the added calories or sugar.
E 954 Sodium Saccharin is available in both tablet and powdered forms and is typically used in small quantities due to its high sweetness potency.
E 954 Sodium Saccharin's heat stability makes it ideal for use in baked goods, such as sugar-free cakes, cookies, and pastries, where it can withstand the high temperatures of baking without breaking down.
E 954 Sodium Saccharin is also commonly used in cooking, especially for preparing sugar-free sauces, dressings, and confectionery.
The ability to maintain its sweetness under heat allows consumers to enjoy sweet flavors in products that would otherwise be off-limits to those reducing their sugar intake.
E 954 Sodium Saccharin does not raise blood sugar levels, it is frequently used in diabetic-friendly foods and medications.
For individuals with diabetes, who need to manage their blood sugar levels carefully, E 954 Sodium Saccharin offers a way to add sweetness without causing glucose spikes.
It is often found in diabetic desserts, snacks, and sugar-free drinks, providing a safe alternative to traditional sugar.
E 954 Sodium Saccharin is a popular ingredient in low-calorie and weight-management foods.
Products like low-calorie yogurts, sugar-free ice creams, and diet-friendly snacks often rely on sodium saccharin to provide sweetness without adding significant calories.
E 954 Sodium Saccharin helps individuals reduce their overall caloric intake while still enjoying the familiar sweet taste in their foods.
E 954 Sodium Saccharin is also used in pharmaceutical formulations, particularly in liquid medicines and oral syrups, to mask the bitter taste of certain medications.
Many medications, especially antibiotics and painkillers, have an inherently bitter taste that can make them difficult to take, especially for children.
E 954 Sodium Saccharin helps improve the palatability of these medications, ensuring better compliance with treatment.
E 954 Sodium Saccharin is sometimes added to toothpaste and mouthwashes as a flavoring agent.
While saccharin does not contribute to dental decay, it can improve the overall taste of oral care products, encouraging their regular use.
Additionally, because E 954 Sodium Saccharin is non-fermentable by oral bacteria, it does not contribute to tooth plaque formation or cavity development, making it a safe choice for oral hygiene.
E 954 Sodium Saccharin is occasionally found in cosmetic products, including skin creams, lotions, and shampoos, where it serves as a sweetening agent or flavor enhancer.
In these products, saccharin helps to improve the sensory experience, giving the product a more pleasant fragrance or taste (especially in products like lip balms or mouthwash).
Safety Profile Of E 954 Sodium Saccharin:
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data.
Moderately toxic by ingestion and intraperitoneal routes.
Experimental reproductive effects human mutation data reported.
When heated to decomposition E 954 Sodium Saccharin emits very toxic fumes of SOx, Na2O, and NOx.
There has been considerable controversy concerning the safety of saccharin and saccharin sodium in recent years; however, it is now generally regarded as a safe, intense sweetener. See Saccharin for further information.
The WHO has set a temporary acceptable daily intake of up to 2.5 mg/kg body-weight for E 954 Sodium Saccharin, including its salts.
In the UK, the Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment (COT) has set an acceptable daily intake for saccharin and its salts (expressed as saccharin sodium) at up to 5 mg/kg body-weight.
In the 1970s, studies performed on laboratory rats found an association between consumption of high doses of E 954 Sodium Saccharin and the development of bladder cancer.
However, further study determined that this eect was due to a mechanism that is not relevant to humans.
Epidemiological studies have shown no evidence that E 954 Sodium Saccharin is associated with bladder cancer in humans.
The International Agency for Research on Cancer (IARC) originally classied saccharin in Group 2B ("possibly carcinogenic to humans") based on the rat studies, but downgraded it to Group 3 ("not classiable as to the carcinogenicity to humans") upon review of the subsequent research.
E 954 Sodium Saccharin has no food energy and no nutritional value.
E 954 Sodium Saccharin is safe to consume for individuals with diabetes.
People with sulfonamide allergies can experience allergic reactions to E 954 Sodium Saccharin, as it is a sulfonamide derivative and can cross-react.
E 954 Sodium Saccharin in toothpaste can cause burning sensations, swelling, and rashes of the mouth and lips in sensitive individuals.
E 954 Sodium Saccharin has been the subject of extensive scientic research.
E 954 Sodium Saccharin is one of the most studied ingredients in the food supply.
Although the totality of the available research indicates E 954 Sodium Saccharin is safe for human consumption, there has been controversy over its safety.
In the 1970s, studies performed on laboratory rats found an association between consumption of high doses of saccharin and the development of bladder cancer.
However, further study determined that this effect was due to a mechanism that is not relevant to humans (deposition of crystals; see § History section).
Epidemiological studies have shown no evidence that E 954 Sodium Saccharin is associated with bladder cancer in humans.
The International Agency for Research on Cancer (IARC) originally classified saccharin in Group 2B ("possibly carcinogenic to humans") based on the rat studies, but downgraded it to Group 3 ("not classifiable as to the carcinogenicity to humans") upon review of the subsequent research.
